| Year |
Citation |
Score |
| 2024 |
Raulin AC, Doss SV, Heckman MG, Craver EC, Li Z, Ikezu TC, Sekiya H, Liu CC, Martens YA, Rosenberg CL, Kuchenbecker LA, DeTure M, Reichard RR, Nguyen AT, Constantopoulos E, et al. Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer's disease. Acta Neuropathologica Communications. 12: 25. PMID 38336940 DOI: 10.1186/s40478-024-01731-0 |
0.604 |
|
| 2023 |
Liu CC, Wang N, Chen Y, Inoue Y, Shue F, Ren Y, Wang M, Qiao W, Ikezu TC, Li Z, Zhao J, Martens Y, Doss SV, Rosenberg CL, Jeevaratnam S, et al. Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease. Nature Immunology. PMID 37857825 DOI: 10.1038/s41590-023-01640-9 |
0.832 |
|
| 2023 |
Macyczko JR, Wang N, Lu W, Jeevaratnam S, Shue F, Martens Y, Liu CC, Kanekiyo T, Bu G, Li Y. Upregulation of sFRP1 Is More Profound in Female than Male 5xFAD Mice and Positively Associated with Amyloid Pathology. Journal of Alzheimer's Disease : Jad. PMID 37545238 DOI: 10.3233/JAD-230218 |
0.761 |
|
| 2023 |
Guo L, Cao J, Hou J, Li Y, Huang M, Zhu L, Zhang L, Lee Y, Duarte ML, Zhou X, Wang M, Liu CC, Martens Y, Chao M, Goate A, et al. Sex specific molecular networks and key drivers of Alzheimer's disease. Molecular Neurodegeneration. 18: 39. PMID 37340466 DOI: 10.1186/s13024-023-00624-5 |
0.546 |
|
| 2023 |
Qiao W, Chen Y, Zhong J, Madden BJ, Charlesworth CM, Martens YA, Liu CC, Knight J, Ikezu TC, Aishe K, Zhu Y, Meneses A, Rosenberg CL, Kuchenbecker LA, Vanmaele LK, et al. Correction: Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology. Molecular Neurodegeneration. 18: 28. PMID 37118783 DOI: 10.1186/s13024-023-00603-w |
0.762 |
|
| 2023 |
Oue H, Yamazaki Y, Qiao W, Yuanxin C, Ren Y, Kurti A, Shue F, Parsons TM, Perkerson RB, Kawatani K, Wang N, Starling SC, Roy B, Mosneag IE, Aikawa T, ... ... Liu CC, et al. LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4. Jci Insight. 8. PMID 37036005 DOI: 10.1172/jci.insight.163822 |
0.804 |
|
| 2023 |
Qiao W, Chen Y, Zhong J, Madden BJ, Charlesworth CM, Martens YA, Liu CC, Knight J, Ikezu TC, Aishe K, Zhu Y, Meneses A, Rosenberg CL, Kuchenbecker LA, Vanmaele LK, et al. Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology. Molecular Neurodegeneration. 18: 8. PMID 36721205 DOI: 10.1186/s13024-023-00599-3 |
0.797 |
|
| 2023 |
Oatman SR, Reddy JS, Quicksall Z, Carrasquillo MM, Wang X, Liu CC, Yamazaki Y, Nguyen TT, Malphrus K, Heckman M, Biswas K, Nho K, Baker M, Martens YA, Zhao N, et al. Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer's disease related proteins. Molecular Neurodegeneration. 18: 2. PMID 36609403 DOI: 10.1186/s13024-022-00592-2 |
0.602 |
|
| 2023 |
Raulin AC, Liu CC, Bu G. An assay to evaluate the capacity of cholesterol acceptors using BODIPY-cholesterol in cells. Star Protocols. 4: 101976. PMID 36598853 DOI: 10.1016/j.xpro.2022.101976 |
0.405 |
|
| 2022 |
Wang N, Wang M, Jeevaratnam S, Rosenberg C, Ikezu TC, Shue F, Doss SV, Alnobani A, Martens YA, Wren M, Asmann YW, Zhang B, Bu G, Liu CC. Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination. Molecular Neurodegeneration. 17: 75. PMID 36419137 DOI: 10.1186/s13024-022-00577-1 |
0.766 |
|
| 2022 |
Raulin AC, Doss SV, Trottier ZA, Ikezu TC, Bu G, Liu CC. ApoE in Alzheimer's disease: pathophysiology and therapeutic strategies. Molecular Neurodegeneration. 17: 72. PMID 36348357 DOI: 10.1186/s13024-022-00574-4 |
0.628 |
|
| 2022 |
Macyczko JR, Wang N, Zhao J, Ren Y, Lu W, Ikezu TC, Zhao N, Liu CC, Bu G, Li Y. Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer's Disease. Molecular Neurobiology. PMID 36215026 DOI: 10.1007/s12035-022-03065-1 |
0.565 |
|
| 2022 |
Zhao N, Qiao W, Li F, Ren Y, Zheng J, Martens YA, Wang X, Li L, Liu CC, Chen K, Zhu Y, Ikezu TC, Li Z, Meneses AD, Jin Y, et al. Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia. The Journal of Experimental Medicine. 219. PMID 36107206 DOI: 10.1084/jem.20212479 |
0.594 |
|
| 2022 |
Chen K, Martens YA, Meneses A, Ryu DH, Lu W, Raulin AC, Li F, Zhao J, Chen Y, Jin Y, Linares C, Goodwin M, Li Y, Liu CC, Kanekiyo T, et al. LRP1 is a neuronal receptor for α-synuclein uptake and spread. Molecular Neurodegeneration. 17: 57. PMID 36056345 DOI: 10.1186/s13024-022-00560-w |
0.458 |
|
| 2022 |
Liu CC, Zhao J, Fu Y, Inoue Y, Ren Y, Chen Y, Doss SV, Shue F, Jeevaratnam S, Bastea L, Wang N, Martens YA, Qiao W, Wang M, Zhao N, et al. Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function. Nature Neuroscience. 25: 1020-1033. PMID 35915180 DOI: 10.1038/s41593-022-01127-0 |
0.808 |
|
| 2022 |
Li Y, Macyczko JR, Liu CC, Bu G. ApoE4 reduction: An emerging and promising therapeutic strategy for Alzheimer's disease. Neurobiology of Aging. 115: 20-28. PMID 35453035 DOI: 10.1016/j.neurobiolaging.2022.03.011 |
0.645 |
|
| 2022 |
Li Z, Heckman MG, Kanekiyo T, Martens YA, Day GS, Vassilaki M, Liu CC, Bennett DA, Petersen RC, Zhao N, Bu G. Clinicopathologic Factors Associated With Reversion to Normal Cognition in Patients With Mild Cognitive Impairment. Neurology. PMID 35314499 DOI: 10.1212/WNL.0000000000200387 |
0.376 |
|
| 2022 |
Martens YA, Zhao N, Liu CC, Kanekiyo T, Yang AJ, Goate AM, Holtzman DM, Bu G. ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias. Neuron. PMID 35298921 DOI: 10.1016/j.neuron.2022.03.004 |
0.565 |
|
| 2021 |
Xie M, Liu YU, Zhao S, Zhang L, Bosco DB, Pang YP, Zhong J, Sheth U, Martens YA, Zhao N, Liu CC, Zhuang Y, Wang L, Dickson DW, Mattson MP, et al. TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration. Nature Neuroscience. PMID 34916658 DOI: 10.1038/s41593-021-00975-6 |
0.481 |
|
| 2021 |
Zhao J, Lu W, Ren Y, Fu Y, Martens YA, Shue F, Davis MD, Wang X, Chen K, Li F, Liu CC, Graff-Radford NR, Wszolek ZK, Younkin SG, Brafman DA, et al. Correction to: Apolipoprotein E regulates lipid metabolism and α‑synuclein pathology in human iPSC‑derived cerebral organoids. Acta Neuropathologica. PMID 34724591 DOI: 10.1007/s00401-021-02380-6 |
0.75 |
|
| 2021 |
Liu CC, Murray ME, Li X, Zhao N, Wang N, Heckman MG, Shue F, Martens Y, Li Y, Raulin AC, Rosenberg CL, Doss SV, Zhao J, Wren MC, Jia L, et al. -Jacksonville (V236E) variant reduces self-aggregation and risk of dementia. Science Translational Medicine. 13: eabc9375. PMID 34586832 DOI: 10.1126/scitranslmed.abc9375 |
0.742 |
|
| 2021 |
Zhao J, Lu W, Ren Y, Fu Y, Martens YA, Shue F, Davis MD, Wang X, Chen K, Li F, Liu CC, Graff-Radford NR, Wszolek ZK, Younkin SG, Brafman DA, et al. Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids. Acta Neuropathologica. PMID 34453582 DOI: 10.1007/s00401-021-02361-9 |
0.802 |
|
| 2021 |
Yamazaki A, Shue F, Yamazaki Y, Martens YA, Bu G, Liu CC. Preparation of single cell suspensions enriched in mouse brain vascular cells for single-cell RNA sequencing. Star Protocols. 2: 100715. PMID 34401781 DOI: 10.1016/j.xpro.2021.100715 |
0.744 |
|
| 2021 |
Martens YA, Xu S, Tait R, Li G, Zhao XC, Lu W, Liu CC, Kanekiyo T, Bu G, Zhao J. Generation and validation of knockout human iPSC-derived cerebral organoids. Star Protocols. 2: 100571. PMID 34151296 DOI: 10.1016/j.xpro.2021.100571 |
0.576 |
|
| 2021 |
Zhao J, Fu Y, Yamazaki Y, Ren Y, Davis MD, Liu CC, Lu W, Wang X, Chen K, Cherukuri Y, Jia L, Martens YA, Job L, Shue F, Nguyen TT, et al. Author Correction: APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids. Nature Communications. 12: 2707. PMID 33953196 DOI: 10.1038/s41467-021-23081-4 |
0.768 |
|
| 2020 |
Yamazaki Y, Liu CC, Yamazaki A, Shue F, Martens YA, Chen Y, Qiao W, Kurti A, Oue H, Ren Y, Li Y, Aikawa T, Cherukuri Y, Fryer JD, Asmann YW, et al. Vascular ApoE4 Impairs Behavior by Modulating Gliovascular Function. Neuron. PMID 33321072 DOI: 10.1016/j.neuron.2020.11.019 |
0.8 |
|
| 2020 |
Wojtas AM, Sens JP, Kang SS, Baker KE, Berry TJ, Kurti A, Daughrity L, Jansen-West KR, Dickson DW, Petrucelli L, Bu G, Liu CC, Fryer JD. Astrocyte-derived clusterin suppresses amyloid formation in vivo. Molecular Neurodegeneration. 15: 71. PMID 33246484 DOI: 10.1186/s13024-020-00416-1 |
0.625 |
|
| 2020 |
Zhao J, Fu Y, Yamazaki Y, Ren Y, Davis MD, Liu CC, Lu W, Wang X, Chen K, Cherukuri Y, Jia L, Martens YA, Job L, Shue F, Nguyen TT, et al. APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids. Nature Communications. 11: 5540. PMID 33139712 DOI: 10.1038/s41467-020-19264-0 |
0.808 |
|
| 2020 |
Hou X, Watzlawik JO, Cook C, Liu CC, Kang SS, Lin WL, DeTure M, Heckman MG, Diehl NN, Al-Shaikh FSH, Walton RL, Ross OA, Melrose HL, Ertekin-Taner N, Bu G, et al. Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33090691 DOI: 10.1002/alz.12198 |
0.537 |
|
| 2020 |
Liu CC, Yamazaki Y, Heckman MG, Martens YA, Jia L, Yamazaki A, Diehl NN, Zhao J, Zhao N, DeTure M, Davis MD, Felton LM, Qiao W, Li Y, Li H, et al. Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32827351 DOI: 10.1002/Alz.12104 |
0.646 |
|
| 2020 |
Rong Z, Cheng B, Zhong L, Ye X, Li X, Jia L, Li Y, Shue F, Wang N, Cheng Y, Huang X, Liu CC, Fryer JD, Wang X, Zhang YW, et al. Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ in triggering receptor expressed on myeloid cells 2 loss-of-function murine models. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32613609 DOI: 10.1096/Fj.202000550Rr |
0.799 |
|
| 2020 |
Zhao N, Ren Y, Yamazaki Y, Qiao W, Li F, Felton LM, Mahmoudiandehkordi S, Kueider-Paisley A, Sonoustoun B, Arnold M, Shue F, Zheng J, Attrebi ON, Martens YA, Li Z, ... ... Liu CC, et al. Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways. Neuron. PMID 32199103 DOI: 10.1016/J.Neuron.2020.02.034 |
0.796 |
|
| 2020 |
Zhao N, Attrebi ON, Ren Y, Qiao W, Sonustun B, Martens YA, Meneses AD, Li F, Shue F, Zheng J, Van Ingelgom AJ, Davis MD, Kurti A, Knight JA, Linares C, ... ... Liu CC, et al. APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid. Science Translational Medicine. 12. PMID 32024798 DOI: 10.1126/Scitranslmed.Aay1809 |
0.798 |
|
| 2019 |
Yamazaki Y, Zhao N, Caulfield TR, Liu CC, Bu G. Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies. Nature Reviews. Neurology. PMID 31367008 DOI: 10.1038/S41582-019-0228-7 |
0.677 |
|
| 2019 |
Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, ... ... Liu CC, et al. Author Correction: Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model. Nature Communications. 10: 2923. PMID 31266955 DOI: 10.1038/S41467-019-10950-2 |
0.504 |
|
| 2019 |
Shinohara M, Shinohara M, Zhao J, Fu Y, Liu CC, Kanekiyo T, Bu G. 5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 Pathway. International Journal of Molecular Sciences. 20. PMID 30934555 DOI: 10.3390/Ijms20061488 |
0.536 |
|
| 2019 |
Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, ... ... Liu CC, et al. Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model. Nature Communications. 10: 1365. PMID 30911003 DOI: 10.1038/S41467-019-09118-9 |
0.627 |
|
| 2019 |
Tachibana M, Holm ML, Liu CC, Shinohara M, Aikawa T, Oue H, Yamazaki Y, Martens YA, Murray ME, Sullivan PM, Weyer K, Glerup S, Dickson DW, Bu G, Kanekiyo T. APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1. The Journal of Clinical Investigation. PMID 30741718 DOI: 10.1172/Jci124853 |
0.671 |
|
| 2018 |
Li H, Liu CC, Zheng H, Huang TY. Amyloid, tau, pathogen infection and antimicrobial protection in Alzheimer's disease -conformist, nonconformist, and realistic prospects for AD pathogenesis. Translational Neurodegeneration. 7: 34. PMID 30603085 DOI: 10.1186/s40035-018-0139-3 |
0.373 |
|
| 2018 |
Zhao N, Liu CC, Van Ingelgom AJ, Linares C, Kurti A, Knight JA, Heckman MG, Diehl NN, Shinohara M, Martens YA, Attrebi ON, Petrucelli L, Fryer JD, Wszolek ZK, Graff-Radford NR, et al. APOE ε2 is associated with increased tau pathology in primary tauopathy. Nature Communications. 9: 4388. PMID 30348994 DOI: 10.1038/S41467-018-06783-0 |
0.589 |
|
| 2017 |
Liu CC, Zhao N, Fu Y, Wang N, Linares C, Tsai CW, Bu G. ApoE4 Accelerates Early Seeding of Amyloid Pathology. Neuron. 96: 1024-1032.e3. PMID 29216449 DOI: 10.1016/J.Neuron.2017.11.013 |
0.658 |
|
| 2017 |
Tachibana M, Yamazaki Y, Liu CC, Bu G, Kanekiyo T. Pericyte implantation in the brain enhances cerebral blood flow and reduces amyloid-β pathology in amyloid model mice. Experimental Neurology. 300: 13-21. PMID 29106980 DOI: 10.1016/J.Expneurol.2017.10.023 |
0.657 |
|
| 2017 |
Kang SS, Kurti A, Baker KE, Liu CC, Colonna M, Ulrich JD, Holtzman DM, Bu G, Fryer JD. Behavioral and transcriptomic analysis of Trem2-null mice: not all knockout mice are created equal. Human Molecular Genetics. PMID 29040522 DOI: 10.1093/Hmg/Ddx366 |
0.569 |
|
| 2017 |
Zhao N, Liu CC, Van Ingelgom AJ, Martens YA, Linares C, Knight JA, Painter MM, Sullivan PM, Bu G. Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes. Neuron. 96: 115-129.e5. PMID 28957663 DOI: 10.1016/J.Neuron.2017.09.003 |
0.562 |
|
| 2017 |
Wojtas AM, Kang SS, Olley BM, Gatherer M, Shinohara M, Lozano PA, Liu CC, Kurti A, Baker KE, Dickson DW, Yue M, Petrucelli L, Bu G, Carare RO, Fryer JD. Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways. Proceedings of the National Academy of Sciences of the United States of America. PMID 28701379 DOI: 10.1016/J.Jalz.2017.06.250 |
0.617 |
|
| 2017 |
Zhao N, Liu CC, Qiao W, Bu G. Apolipoprotein E, Receptors, and Modulation of Alzheimer's Disease. Biological Psychiatry. PMID 28434655 DOI: 10.1016/J.Biopsych.2017.03.003 |
0.669 |
|
| 2017 |
Liu CC, Hu J, Zhao N, Wang J, Na W, Cirrito JR, Kanekiyo T, Holtzman DM, Bu G. Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28275161 DOI: 10.1523/Jneurosci.3442-16.2017 |
0.618 |
|
| 2017 |
Rogers JT, Liu CC, Zhao N, Wang J, Putzke T, Yang L, Shinohara M, Fryer JD, Kanekiyo T, Bu G. Subacute ibuprofen treatment rescues the synaptic and cognitive deficits in advanced-aged mice. Neurobiology of Aging. 53: 112-121. PMID 28254590 DOI: 10.1016/J.Neurobiolaging.2017.02.001 |
0.481 |
|
| 2017 |
Zhong L, Chen XF, Wang T, Wang Z, Liao C, Wang Z, Huang R, Wang D, Li X, Wu L, Jia L, Zheng H, Painter M, Atagi Y, Liu CC, et al. Soluble TREM2 induces inflammatory responses and enhances microglial survival. The Journal of Experimental Medicine. PMID 28209725 DOI: 10.1084/Jem.20160844 |
0.543 |
|
| 2017 |
Zheng H, Jia L, Liu CC, Li Zhong ZR, Yang L, Chen XF, Fryer JD, Wang X, Zhang YW, Xu H, Bu G. TREM2 promotes microglial survival by activating Wnt/β-catenin pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28077724 DOI: 10.1523/Jneurosci.2459-16.2017 |
0.546 |
|
| 2017 |
Kang SS, Ren Y, Liu CC, Kurti A, Baker KE, Bu G, Asmann Y, Fryer JD. Lipocalin-2 protects the brain during inflammatory conditions. Molecular Psychiatry. PMID 28070126 DOI: 10.1038/Mp.2016.243 |
0.312 |
|
| 2016 |
Yang L, Liu CC, Zheng H, Kanekiyo T, Atagi Y, Jia L, Wang D, N'songo A, Can D, Xu H, Chen XF, Bu G. LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways. Journal of Neuroinflammation. 13: 304. PMID 27931217 DOI: 10.1186/S12974-016-0772-7 |
0.562 |
|
| 2016 |
Kang SS, Kurti A, Wojtas A, Baker KE, Liu CC, Kanekiyo T, Deming Y, Cruchaga C, Estus S, Bu G, Fryer JD. Identification of Plexin A4 as a novel Clusterin receptor links two Alzheimer's disease risk genes. Human Molecular Genetics. PMID 27378688 DOI: 10.1093/Hmg/Ddw188 |
0.626 |
|
| 2016 |
Shinohara M, Murray ME, Frank RD, Shinohara M, DeTure M, Yamazaki Y, Tachibana M, Atagi Y, Davis MD, Liu CC, Zhao N, Painter MM, Petersen RC, Fryer JD, Crook JE, et al. Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease. Acta Neuropathologica. PMID 27179972 DOI: 10.1007/S00401-016-1580-Y |
0.603 |
|
| 2016 |
Huang YN, Lin CI, Liao H, Liu CY, Chen YH, Chiu WC, Lin SH. Cholesterol overload induces apoptosis in SH-SY5Y human neuroblastoma cells through the up regulation of flotillin-2 in the lipid raft and the activation of BDNF/Trkb signaling. Neuroscience. PMID 27155148 DOI: 10.1016/j.neuroscience.2016.04.043 |
0.364 |
|
| 2016 |
Fu Y, Zhao J, Atagi Y, Nielsen HM, Liu CC, Zheng H, Shinohara M, Kanekiyo T, Bu G. Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycan. Molecular Neurodegeneration. 11: 37. PMID 27151330 DOI: 10.1186/S13024-016-0099-Y |
0.612 |
|
| 2016 |
Zheng H, Liu CC, Atagi Y, Chen XF, Jia L, Yang L, He W, Zhang X, Kang SS, Rosenberry TL, Fryer JD, Zhang YW, Xu H, Bu G. Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation. Neurobiology of Aging. 42: 132-41. PMID 27143430 DOI: 10.1016/J.Neurobiolaging.2016.03.004 |
0.635 |
|
| 2016 |
Zhang X, Hu J, Zhong L, Wang N, Yang L, Liu CC, Li H, Wang X, Zhou Y, Zhang Y, Xu H, Bu G, Zhuang J. Quercetin stabilizes apolipoprotein E and reduces brain Aβ levels in amyloid model mice. Neuropharmacology. PMID 27114256 DOI: 10.1016/J.Neuropharm.2016.04.032 |
0.634 |
|
| 2016 |
Sakae N, Liu CC, Shinohara M, Frisch-Daiello J, Ma L, Yamazaki Y, Tachibana M, Younkin L, Kurti A, Carrasquillo MM, Zou F, Sevlever D, Bisceglio G, Gan M, Fol R, et al. ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3848-59. PMID 27030769 DOI: 10.1523/Jneurosci.3757-15.2016 |
0.597 |
|
| 2016 |
Liu CC, Zhao N, Yamaguchi Y, Cirrito JR, Kanekiyo T, Holtzman DM, Bu G. Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease. Science Translational Medicine. 8: 332ra44. PMID 27030596 DOI: 10.1126/Scitranslmed.Aad3650 |
0.655 |
|
| 2016 |
Yamazaki Y, Baker DJ, Tachibana M, Liu CC, van Deursen JM, Brott TG, Bu G, Kanekiyo T. Vascular Cell Senescence Contributes to Blood-Brain Barrier Breakdown. Stroke; a Journal of Cerebral Circulation. PMID 26883501 DOI: 10.1161/Strokeaha.115.010835 |
0.461 |
|
| 2016 |
Zheng H, Liu CC, Atagi Y, Chen XF, Jia L, Yang L, He W, Zhang X, Kang SS, Rosenberry TL, Fryer JD, Zhang YW, Xu H, Bu G. Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation Neurobiology of Aging. 42: 132-141. DOI: 10.1016/j.neurobiolaging.2016.03.004 |
0.587 |
|
| 2015 |
Tachibana M, Shinohara M, Yamazaki Y, Liu CC, Rogers J, Bu G, Kanekiyo T. Rescuing Effects of RXR Agonist Bexarotene on Aging-related Synapse Loss Depend on Neuronal LRP1. Experimental Neurology. PMID 26688581 DOI: 10.1016/j.expneurol.2015.12.003 |
0.48 |
|
| 2015 |
Atagi Y, Liu CC, Painter MM, Chen XF, Verbeeck C, Zheng H, Li X, Rademakers R, Kang SS, Xu H, Younkin S, Das P, Fryer JD, Bu G. Apolipoprotein E is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2). The Journal of Biological Chemistry. PMID 26374899 DOI: 10.1074/Jbc.M115.679043 |
0.585 |
|
| 2015 |
Wren MC, Zhao J, Liu CC, Murray ME, Atagi Y, Davis MD, Fu Y, Okano HJ, Ogaki K, Strongosky AJ, Tacik P, Rademakers R, Ross OA, Dickson DW, Wszolek ZK, et al. Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells. Molecular Neurodegeneration. 10: 46. PMID 26373282 DOI: 10.1186/S13024-015-0042-7 |
0.484 |
|
| 2015 |
Painter MM, Atagi Y, Liu CC, Rademakers R, Xu H, Fryer JD, Bu G. TREM2 in CNS homeostasis and neurodegenerative disease. Molecular Neurodegeneration. 10: 43. PMID 26337043 DOI: 10.1186/S13024-015-0040-9 |
0.494 |
|
| 2015 |
Harriott AM, Heckman MG, Rayaprolu S, Soto-Ortolaza AI, Diehl NN, Kanekiyo T, Liu CC, Bu G, Malik R, Cole JW, Meschia JF, Ross OA. Low density lipoprotein receptor related protein 1 and 6 gene variants and ischaemic stroke risk. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 22: 1235-41. PMID 26031789 DOI: 10.1111/Ene.12735 |
0.393 |
|
| 2015 |
Hu J, Liu CC, Chen XF, Zhang YW, Xu H, Bu G. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice. Molecular Neurodegeneration. 10: 6. PMID 25871773 DOI: 10.1186/S13024-015-0001-3 |
0.671 |
|
| 2015 |
Liu CC, Hu J, Tsai CW, Yue M, Melrose HL, Kanekiyo T, Bu G. Neuronal LRP1 regulates glucose metabolism and insulin signaling in the brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5851-9. PMID 25855193 DOI: 10.1523/Jneurosci.5180-14.2015 |
0.533 |
|
| 2014 |
Liu CC, Tsai CW, Deak F, Rogers J, Penuliar M, Sung YM, Maher JN, Fu Y, Li X, Xu H, Estus S, Hoe HS, Fryer JD, Kanekiyo T, Bu G. Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease. Neuron. 84: 63-77. PMID 25242217 DOI: 10.1016/J.Neuron.2014.08.048 |
0.643 |
|
| 2014 |
Liu CC, Kanekiyo T, Roth B, Bu G. Tyrosine-based signal mediates LRP6 receptor endocytosis and desensitization of Wnt/β-catenin pathway signaling. The Journal of Biological Chemistry. 289: 27562-70. PMID 25143377 DOI: 10.1074/Jbc.M113.533927 |
0.423 |
|
| 2014 |
Zhao J, Fu Y, Liu CC, Shinohara M, Nielsen HM, Dong Q, Kanekiyo T, Bu G. Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway. The Journal of Biological Chemistry. 289: 11282-92. PMID 24599963 DOI: 10.1074/Jbc.M113.526095 |
0.517 |
|
| 2013 |
Kanekiyo T, Cirrito JR, Liu CC, Shinohara M, Li J, Schuler DR, Shinohara M, Holtzman DM, Bu G. Neuronal clearance of amyloid-β by endocytic receptor LRP1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 19276-83. PMID 24305823 DOI: 10.1523/Jneurosci.3487-13.2013 |
0.57 |
|
| 2013 |
Liu CC, Liu CC, Kanekiyo T, Xu H, Bu G. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nature Reviews. Neurology. 9: 106-18. PMID 23296339 DOI: 10.1038/Nrneurol.2012.263 |
0.601 |
|
| 2013 |
Bu G, Liu C, Kanekiyo T. Vascular hypothesis of Alzheimer’s disease: role of apoE and apoE receptors Molecular Neurodegeneration. 8. DOI: 10.1186/1750-1326-8-S1-O20 |
0.662 |
|
| 2012 |
Kanekiyo T, Liu CC, Shinohara M, Li J, Bu G. LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16458-65. PMID 23152628 DOI: 10.1523/Jneurosci.3987-12.2012 |
0.571 |
|
| 2012 |
Liu C, Hoe H, Bu G. Wnt signaling receptor LRP6 interacts with amyloid precursor protein and regulates its trafficking and processing Molecular Neurodegeneration. 7: O5. DOI: 10.1186/1750-1326-7-S1-O5 |
0.634 |
|
| 2011 |
Chen J, Liu CC, Li Q, Nowak C, Bu G, Wang J. Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6. Structure (London, England : 1993). 19: 313-23. PMID 21397183 DOI: 10.1016/J.Str.2011.01.010 |
0.359 |
|
| 2011 |
Kanekiyo T, Zhang J, Liu Q, Liu CC, Zhang L, Bu G. Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1644-51. PMID 21289173 DOI: 10.1523/Jneurosci.5491-10.2011 |
0.551 |
|
| 2010 |
Li Y, Lu W, King TD, Liu CC, Bijur GN, Bu G. Dkk1 stabilizes Wnt co-receptor LRP6: implication for Wnt ligand-induced LRP6 down-regulation. Plos One. 5: e11014. PMID 20543981 DOI: 10.1371/Journal.Pone.0011014 |
0.428 |
|
| 2010 |
Chen J, Li Q, Liu CC, Zhou P, Zhou B, Bu G, Wang J. NMR structure note: solution structure of the core domain of MESD that is essential for proper folding of LRP5/6. Journal of Biomolecular Nmr. 47: 283-8. PMID 20506034 DOI: 10.1007/s10858-010-9426-8 |
0.318 |
|
| 2010 |
Lu W, Liu CC, Thottassery JV, Bu G, Li Y. Mesd is a universal inhibitor of Wnt coreceptors LRP5 and LRP6 and blocks Wnt/beta-catenin signaling in cancer cells. Biochemistry. 49: 4635-43. PMID 20446724 DOI: 10.1021/Bi1001486 |
0.393 |
|
| 2010 |
Liu CC, Prior J, Piwnica-Worms D, Bu G. LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy. Proceedings of the National Academy of Sciences of the United States of America. 107: 5136-41. PMID 20194742 DOI: 10.1073/Pnas.0911220107 |
0.357 |
|
| 2009 |
Liu CC, Pearson C, Bu G. Cooperative folding and ligand-binding properties of LRP6 beta-propeller domains. The Journal of Biological Chemistry. 284: 15299-307. PMID 19339249 DOI: 10.1074/jbc.M807285200 |
0.383 |
|
| 2008 |
Bu G, Lu W, Liu CC, Selander K, Yoneda T, Hall C, Keller ET, Li Y. Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases. International Journal of Cancer. Journal International Du Cancer. 123: 1034-42. PMID 18546262 DOI: 10.1002/Ijc.23625 |
0.352 |
|
| 2006 |
Yamazaki Y, Liu C, Oue H, Kurti A, Yamazaki A, Fryer JD, Kanekiyo T, Bu G. P4-065: APOE4 CONDITIONALLY EXPRESSED IN CEREBROVASCULATURE IMPAIRS ENDOTHELIAL FUNCTIONS AND INDUCES COGNITIVE DEFICITS Alzheimer's & Dementia. 14: P1457-P1458. DOI: 10.1016/J.Jalz.2018.06.2468 |
0.474 |
|
| 2001 |
Liu CX, Li Y, Obermoeller-McCormick LM, Schwartz AL, Bu G. The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein. The Journal of Biological Chemistry. 276: 28889-96. PMID 11384978 DOI: 10.1074/jbc.M102727200 |
0.404 |
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