| Year |
Citation |
Score |
| 2015 |
Iyer RR, Pluciennik A, Napierala M, Wells RD. DNA triplet repeat expansion and mismatch repair. Annual Review of Biochemistry. 84: 199-226. PMID 25580529 DOI: 10.1146/Annurev-Biochem-060614-034010 |
0.709 |
|
| 2013 |
Polak U, McIvor E, Dent SY, Wells RD, Napierala M. Expanded complexity of unstable repeat diseases. Biofactors (Oxford, England). 39: 164-75. PMID 23233240 DOI: 10.1002/Biof.1060 |
0.343 |
|
| 2010 |
Berrington WR, Iyer R, Wells RD, Smith KD, Skerrett SJ, Hawn TR. NOD1 and NOD2 regulation of pulmonary innate immunity to Legionella pneumophila. European Journal of Immunology. 40: 3519-27. PMID 21108472 DOI: 10.1002/eji.201040518 |
0.496 |
|
| 2010 |
Lin Y, Dent SY, Wilson JH, Wells RD, Napierala M. R loops stimulate genetic instability of CTG.CAG repeats. Proceedings of the National Academy of Sciences of the United States of America. 107: 692-7. PMID 20080737 DOI: 10.1073/Pnas.0909740107 |
0.539 |
|
| 2010 |
Wells RD. Actinomycin Binding to DNA: Inability of a DNA Containing Guanine To Bind Actinomycin D. Science (New York, N.Y.). 165: 75-6. PMID 17840693 DOI: 10.1126/Science.165.3888.75 |
0.484 |
|
| 2009 |
Chuzhanova N, Chen JM, Bacolla A, Patrinos GP, Férec C, Wells RD, Cooper DN. Gene conversion causing human inherited disease: evidence for involvement of non-B-DNA-forming sequences and recombination-promoting motifs in DNA breakage and repair. Human Mutation. 30: 1189-98. PMID 19431182 DOI: 10.1002/Humu.21020 |
0.517 |
|
| 2009 |
Bacolla A, Wells RD. Non-B DNA conformations as determinants of mutagenesis and human disease. Molecular Carcinogenesis. 48: 273-85. PMID 19306308 DOI: 10.1002/Mc.20507 |
0.529 |
|
| 2009 |
Wells RD. Discovery of the role of non-B DNA structures in mutagenesis and human genomic disorders. The Journal of Biological Chemistry. 284: 8997-9009. PMID 19054760 DOI: 10.1074/Jbc.X800010200 |
0.539 |
|
| 2009 |
Wells RD. Mutation spectra in fragile X syndrome induced by deletions of CGG*CCG repeats. The Journal of Biological Chemistry. 284: 7407-11. PMID 18957433 DOI: 10.1074/jbc.R800024200 |
0.324 |
|
| 2008 |
Bacolla A, Larson JE, Collins JR, Li J, Milosavljevic A, Stenson PD, Cooper DN, Wells RD. Abundance and length of simple repeats in vertebrate genomes are determined by their structural properties. Genome Research. 18: 1545-53. PMID 18687880 DOI: 10.1101/Gr.078303.108 |
0.394 |
|
| 2008 |
Wells RD. DNA triplexes and Friedreich ataxia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1625-34. PMID 18211957 DOI: 10.1096/Fj.07-097857 |
0.531 |
|
| 2007 |
Kosmider B, Wells RD. Fragile X repeats are potent inducers of complex, multiple site rearrangements in flanking sequences in Escherichia coli. Dna Repair. 6: 1850-63. PMID 17851139 DOI: 10.1016/J.Dnarep.2007.07.014 |
0.466 |
|
| 2007 |
Wells RD. Non-B DNA conformations, mutagenesis and disease. Trends in Biochemical Sciences. 32: 271-8. PMID 17493823 DOI: 10.1016/J.Tibs.2007.04.003 |
0.531 |
|
| 2006 |
Kosmider B, Wells RD. Double-strand breaks in the myotonic dystrophy type 1 and the fragile X syndrome triplet repeat sequences induce different types of mutations in DNA flanking sequences in Escherichia coli. Nucleic Acids Research. 34: 5369-82. PMID 17012280 DOI: 10.1093/Nar/Gkl612 |
0.548 |
|
| 2006 |
Burnett R, Melander C, Puckett JW, Son LS, Wells RD, Dervan PB, Gottesfeld JM. DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia. Proceedings of the National Academy of Sciences of the United States of America. 103: 11497-502. PMID 16857735 DOI: 10.1073/Pnas.0604939103 |
0.528 |
|
| 2006 |
Bacolla A, Wojciechowska M, Kosmider B, Larson JE, Wells RD. The involvement of non-B DNA structures in gross chromosomal rearrangements. Dna Repair. 5: 1161-70. PMID 16807140 DOI: 10.1016/J.Dnarep.2006.05.032 |
0.494 |
|
| 2006 |
Wojciechowska M, Napierala M, Larson JE, Wells RD. Non-B DNA conformations formed by long repeating tracts of myotonic dystrophy type 1, myotonic dystrophy type 2, and Friedreich's ataxia genes, not the sequences per se, promote mutagenesis in flanking regions. The Journal of Biological Chemistry. 281: 24531-43. PMID 16793772 DOI: 10.1074/Jbc.M603888200 |
0.54 |
|
| 2006 |
Son LS, Bacolla A, Wells RD. Sticky DNA: in vivo formation in E. coli and in vitro association of long GAA*TTC tracts to generate two independent supercoiled domains. Journal of Molecular Biology. 360: 267-84. PMID 16764889 DOI: 10.1016/J.Jmb.2006.05.025 |
0.586 |
|
| 2006 |
Dere R, Wells RD. DM2 CCTG*CAGG repeats are crossover hotspots that are more prone to expansions than the DM1 CTG*CAG repeats in Escherichia coli. Journal of Molecular Biology. 360: 21-36. PMID 16753177 DOI: 10.1016/J.Jmb.2006.05.012 |
0.499 |
|
| 2006 |
Son LS, Wells RD. Triplexes, sticky DNA, and the (GAA·TTC) trinucleotide repeat associated with Friedreich's ataxia Genetic Instabilities and Neurological Diseases, Second Edition. 327-335. DOI: 10.1016/B978-012369462-1/50022-3 |
0.397 |
|
| 2005 |
Hebert ML, Wells RD. Roles of double-strand breaks, nicks, and gaps in stimulating deletions of CTG.CAG repeats by intramolecular DNA repair. Journal of Molecular Biology. 353: 961-79. PMID 16213518 DOI: 10.1016/J.Jmb.2005.09.023 |
0.512 |
|
| 2005 |
Napierala M, Bacolla A, Wells RD. Increased negative superhelical density in vivo enhances the genetic instability of triplet repeat sequences. The Journal of Biological Chemistry. 280: 37366-76. PMID 16166072 DOI: 10.1074/Jbc.M508065200 |
0.575 |
|
| 2005 |
Wells RD, Dere R, Hebert ML, Napierala M, Son LS. Advances in mechanisms of genetic instability related to hereditary neurological diseases. Nucleic Acids Research. 33: 3785-98. PMID 16006624 DOI: 10.1093/Nar/Gki697 |
0.551 |
|
| 2005 |
Wojciechowska M, Bacolla A, Larson JE, Wells RD. The myotonic dystrophy type 1 triplet repeat sequence induces gross deletions and inversions. The Journal of Biological Chemistry. 280: 941-52. PMID 15489504 DOI: 10.1074/Jbc.M410427200 |
0.478 |
|
| 2004 |
Bacolla A, Jaworski A, Larson JE, Jakupciak JP, Chuzhanova N, Abeysinghe SS, O'Connell CD, Cooper DN, Wells RD. Breakpoints of gross deletions coincide with non-B DNA conformations. Proceedings of the National Academy of Sciences of the United States of America. 101: 14162-7. PMID 15377784 DOI: 10.1073/Pnas.0405974101 |
0.527 |
|
| 2004 |
Bacolla A, Wells RD. Non-B DNA conformations, genomic rearrangements, and human disease. The Journal of Biological Chemistry. 279: 47411-4. PMID 15326170 DOI: 10.1074/Jbc.R400028200 |
0.577 |
|
| 2004 |
Mochmann LH, Wells RD. Transcription influences the types of deletion and expansion products in an orientation-dependent manner from GAC*GTC repeats. Nucleic Acids Research. 32: 4469-79. PMID 15317871 DOI: 10.1093/Nar/Gkh787 |
0.36 |
|
| 2004 |
Dere R, Napierala M, Ranum LP, Wells RD. Hairpin structure-forming propensity of the (CCTG.CAGG) tetranucleotide repeats contributes to the genetic instability associated with myotonic dystrophy type 2. The Journal of Biological Chemistry. 279: 41715-26. PMID 15292165 DOI: 10.1074/Jbc.M406415200 |
0.436 |
|
| 2004 |
Hebert ML, Spitz LA, Wells RD. DNA double-strand breaks induce deletion of CTG.CAG repeats in an orientation-dependent manner in Escherichia coli. Journal of Molecular Biology. 336: 655-72. PMID 15095979 DOI: 10.1016/J.Jmb.2003.12.038 |
0.554 |
|
| 2004 |
Vetcher AA, Wells RD. Sticky DNA formation in vivo alters the plasmid dimer/monomer ratio. The Journal of Biological Chemistry. 279: 6434-43. PMID 14625291 DOI: 10.1074/Jbc.M309595200 |
0.803 |
|
| 2004 |
Napierala M, Dere R, Vetcher A, Wells RD. Structure-dependent recombination hot spot activity of GAA.TTC sequences from intron 1 of the Friedreich's ataxia gene. The Journal of Biological Chemistry. 279: 6444-54. PMID 14625270 DOI: 10.1074/Jbc.M309596200 |
0.778 |
|
| 2003 |
Meservy JL, Sargent RG, Iyer RR, Chan F, McKenzie GJ, Wells RD, Wilson JH. Long CTG tracts from the myotonic dystrophy gene induce deletions and rearrangements during recombination at the APRT locus in CHO cells. Molecular and Cellular Biology. 23: 3152-62. PMID 12697816 DOI: 10.1128/Mcb.23.9.3152-3162.2003 |
0.671 |
|
| 2002 |
Tomita N, Fujita R, Kurihara D, Shindo H, Wells RD, Shimizu M. Effects of triplet repeat sequences on nucleosome positioning and gene expression in yeast minichromosomes. Nucleic Acids Research. Supplement (2001). 231-2. PMID 12903190 |
0.33 |
|
| 2002 |
Vetcher AA, Napierala M, Wells RD. Sticky DNA: effect of the polypurine.polypyrimidine sequence. The Journal of Biological Chemistry. 277: 39228-34. PMID 12161438 DOI: 10.1074/Jbc.M205210200 |
0.794 |
|
| 2002 |
Vetcher AA, Napierala M, Iyer RR, Chastain PD, Griffith JD, Wells RD. Sticky DNA, a long GAA.GAA.TTC triplex that is formed intramolecularly, in the sequence of intron 1 of the frataxin gene. The Journal of Biological Chemistry. 277: 39217-27. PMID 12161437 DOI: 10.1074/Jbc.M205209200 |
0.829 |
|
| 2002 |
Pluciennik A, Iyer RR, Napierala M, Larson JE, Filutowicz M, Wells RD. Long CTG.CAG repeats from myotonic dystrophy are preferred sites for intermolecular recombination. The Journal of Biological Chemistry. 277: 34074-86. PMID 12087090 DOI: 10.1074/Jbc.M202127200 |
0.72 |
|
| 2002 |
Napierala M, Parniewski P, Pluciennik A, Wells RD. Long CTG.CAG repeat sequences markedly stimulate intramolecular recombination. The Journal of Biological Chemistry. 277: 34087-100. PMID 12045198 DOI: 10.1074/Jbc.M202128200 |
0.447 |
|
| 2001 |
Shimizu M, Fujita R, Tomita N, Shindo H, Wells RD. Chromatin structure of yeast minichromosomes containing triplet repeat sequences associated with human hereditary neurological diseases. Nucleic Acids Research. Supplement (2001). 71-2. PMID 12836269 |
0.302 |
|
| 2001 |
Bacolla A, Pradhan S, Larson JE, Roberts RJ, Wells RD. Recombinant human DNA (cytosine-5) methyltransferase. III. Allosteric control, reaction order, and influence of plasmid topology and triplet repeat length on methylation of the fragile X CGG.CCG sequence. The Journal of Biological Chemistry. 276: 18605-13. PMID 11359795 DOI: 10.1074/Jbc.M100404200 |
0.49 |
|
| 2001 |
Sakamoto N, Ohshima K, Montermini L, Pandolfo M, Wells RD. Sticky DNA, a self-associated complex formed at long GAA*TTC repeats in intron 1 of the frataxin gene, inhibits transcription. The Journal of Biological Chemistry. 276: 27171-7. PMID 11340071 DOI: 10.1074/Jbc.M101879200 |
0.54 |
|
| 2001 |
Sakamoto N, Larson JE, Iyer RR, Montermini L, Pandolfo M, Wells RD. GGA*TCC-interrupted triplets in long GAA*TTC repeats inhibit the formation of triplex and sticky DNA structures, alleviate transcription inhibition, and reduce genetic instabilities. The Journal of Biological Chemistry. 276: 27178-87. PMID 11325966 DOI: 10.1074/Jbc.M101852200 |
0.728 |
|
| 2001 |
Bacolla A, Jaworski A, Connors TD, Wells RD. Pkd1 unusual DNA conformations are recognized by nucleotide excision repair. The Journal of Biological Chemistry. 276: 18597-604. PMID 11279140 DOI: 10.1074/Jbc.M100845200 |
0.474 |
|
| 2001 |
Bowater RP, Wells RD. The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders. Progress in Nucleic Acid Research and Molecular Biology. 66: 159-202. PMID 11051764 DOI: 10.1016/S0079-6603(00)66029-4 |
0.573 |
|
| 2000 |
Jakupciak JP, Wells RD. Genetic instabilities of triplet repeat sequences by recombination. Iubmb Life. 50: 355-9. PMID 11327307 DOI: 10.1080/713803749 |
0.45 |
|
| 2000 |
Jakupciak JP, Wells RD. Gene conversion (recombination) mediates expansions of CTG[middle dot]CAG repeats. The Journal of Biological Chemistry. 275: 40003-13. PMID 11005819 DOI: 10.1074/Jbc.M007153200 |
0.444 |
|
| 2000 |
Pluciennik A, Iyer RR, Parniewski P, Wells RD. Tandem duplication. A novel type of triplet repeat instability. The Journal of Biological Chemistry. 275: 28386-97. PMID 10877999 DOI: 10.1074/Jbc.M000154200 |
0.708 |
|
| 2000 |
Parniewski P, Jaworski A, Wells RD, Bowater RP. Length of CTG.CAG repeats determines the influence of mismatch repair on genetic instability. Journal of Molecular Biology. 299: 865-74. PMID 10843843 DOI: 10.1006/Jmbi.2000.3796 |
0.469 |
|
| 2000 |
Iyer RR, Pluciennik A, Rosche WA, Sinden RR, Wells RD. DNA polymerase III proofreading mutants enhance the expansion and deletion of triplet repeat sequences in Escherichia coli. The Journal of Biological Chemistry. 275: 2174-84. PMID 10636923 DOI: 10.1074/Jbc.275.3.2174 |
0.637 |
|
| 2000 |
Parniewski P, Jaworski A, Wells RD, Bowater RP. Effect of Repeat Tract Length on Expansions and Deletions of CTG.CAG Repeats Mediated by Mismatch Repair in Escherichia coli Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A168 |
0.395 |
|
| 1999 |
Ohshima K, Sakamoto N, Labuda M, Poirier J, Moseley ML, Montermini L, Ranum LP, Wells RD, Pandolfo M. A nonpathogenic GAAGGA repeat in the Friedreich gene: implications for pathogenesis. Neurology. 53: 1854-7. PMID 10563639 DOI: 10.1212/Wnl.53.8.1854 |
0.325 |
|
| 1999 |
Bacolla A, Pradhan S, Roberts RJ, Wells RD. Recombinant human DNA (cytosine-5) methyltransferase. II. Steady-state kinetics reveal allosteric activation by methylated dna. The Journal of Biological Chemistry. 274: 33011-9. PMID 10551869 DOI: 10.1074/Jbc.274.46.33011 |
0.52 |
|
| 1999 |
Pradhan S, Bacolla A, Wells RD, Roberts RJ. Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation. The Journal of Biological Chemistry. 274: 33002-10. PMID 10551868 DOI: 10.1074/Jbc.274.46.33002 |
0.433 |
|
| 1999 |
Jakupciak JP, Wells RD. Genetic instabilities in (CTG.CAG) repeats occur by recombination. The Journal of Biological Chemistry. 274: 23468-79. PMID 10438526 DOI: 10.1074/Jbc.274.33.23468 |
0.471 |
|
| 1999 |
Sakamoto N, Chastain PD, Parniewski P, Ohshima K, Pandolfo M, Griffith JD, Wells RD. Sticky DNA: self-association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich's ataxia. Molecular Cell. 3: 465-75. PMID 10230399 DOI: 10.1016/S1097-2765(00)80474-8 |
0.47 |
|
| 1999 |
Iyer RR, Wells RD. Expansion and deletion of triplet repeat sequences in Escherichia coli occur on the leading strand of DNA replication. The Journal of Biological Chemistry. 274: 3865-77. PMID 9920942 DOI: 10.1074/Jbc.274.6.3865 |
0.727 |
|
| 1999 |
Parniewski P, Bacolla A, Jaworski A, Wells RD. Nucleotide excision repair affects the stability of long transcribed (CTG*CAG) tracts in an orientation-dependent manner in Escherichia coli. Nucleic Acids Research. 27: 616-23. PMID 9862988 DOI: 10.1093/Nar/27.2.616 |
0.531 |
|
| 1999 |
Samadashwily GM, Raca G, Mirkin SM, Iyer RR, Wells RD. Trinucleotide repeats affect DNA replication in vivo Chemtracts. 12: 724-733. |
0.454 |
|
| 1998 |
Wells RD, Parniewski P, Pluciennik A, Bacolla A, Gellibolian R, Jaworski A. Small slipped register genetic instabilities in Escherichia coli in triplet repeat sequences associated with hereditary neurological diseases. The Journal of Biological Chemistry. 273: 19532-41. PMID 9677376 DOI: 10.1074/Jbc.273.31.19532 |
0.484 |
|
| 1998 |
Wells RD, Bacolla A, Bowater RP. Instabilities of triplet repeats: factors and mechanisms. Results and Problems in Cell Differentiation. 21: 133-65. PMID 9670316 DOI: 10.1007/978-3-540-69680-3_4 |
0.39 |
|
| 1998 |
Ohshima K, Montermini L, Wells RD, Pandolfo M. Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo. The Journal of Biological Chemistry. 273: 14588-95. PMID 9603975 DOI: 10.1074/Jbc.273.23.14588 |
0.379 |
|
| 1998 |
Wells RD. DNA structure, triplet repeats, and hereditary neurological diseases Journal of Biochemistry and Molecular Biology. 31: 2-19. |
0.39 |
|
| 1997 |
Bowater RP, Jaworski A, Larson JE, Parniewski P, Wells RD. Transcription increases the deletion frequency of long CTG.CAG triplet repeats from plasmids in Escherichia coli. Nucleic Acids Research. 25: 2861-8. PMID 9207036 DOI: 10.1093/Nar/25.14.2861 |
0.448 |
|
| 1997 |
Ohshima K, Wells RD. Hairpin formation during DNA synthesis primer realignment in vitro in triplet repeat sequences from human hereditary disease genes. The Journal of Biological Chemistry. 272: 16798-806. PMID 9201985 DOI: 10.1074/Jbc.272.27.16798 |
0.599 |
|
| 1997 |
Gellibolian R, Bacolla A, Wells RD. Triplet repeat instability and DNA topology: an expansion model based on statistical mechanics. The Journal of Biological Chemistry. 272: 16793-7. PMID 9201984 DOI: 10.1074/Jbc.272.27.16793 |
0.489 |
|
| 1997 |
Bacolla A, Gellibolian R, Shimizu M, Amirhaeri S, Kang S, Ohshima K, Larson JE, Harvey SC, Stollar BD, Wells RD. Flexible DNA: genetically unstable CTG.CAG and CGG.CCG from human hereditary neuromuscular disease genes. The Journal of Biological Chemistry. 272: 16783-92. PMID 9201983 DOI: 10.1074/Jbc.272.27.16783 |
0.522 |
|
| 1996 |
Bowater RP, Rosche WA, Jaworski A, Sinden RR, Wells RD. Relationship between Escherichia coli growth and deletions of CTG.CAG triplet repeats in plasmids. Journal of Molecular Biology. 264: 82-96. PMID 8950269 DOI: 10.1006/Jmbi.1996.0625 |
0.432 |
|
| 1996 |
Wang YH, Gellibolian R, Shimizu M, Wells RD, Griffith J. Long CCG triplet repeat blocks exclude nucleosomes: a possible mechanism for the nature of fragile sites in chromosomes. Journal of Molecular Biology. 263: 511-6. PMID 8918933 DOI: 10.1006/Jmbi.1996.0593 |
0.363 |
|
| 1996 |
Rosche WA, Jaworski A, Kang S, Kramer SF, Larson JE, Geidroc DP, Wells RD, Sinden RR. Single-stranded DNA-binding protein enhances the stability of CTG triplet repeats in Escherichia coli. Journal of Bacteriology. 178: 5042-4. PMID 8759875 DOI: 10.1128/Jb.178.16.5042-5044.1996 |
0.476 |
|
| 1996 |
Ohshima K, Kang S, Larson JE, Wells RD. TTA.TAA triplet repeats in plasmids form a non-H bonded structure. The Journal of Biological Chemistry. 271: 16784-91. PMID 8663378 DOI: 10.1074/Jbc.271.28.16784 |
0.364 |
|
| 1996 |
Ohshima K, Kang S, Larson JE, Wells RD. Cloning, characterization, and properties of seven triplet repeat DNA sequences. The Journal of Biological Chemistry. 271: 16773-83. PMID 8663377 DOI: 10.1074/Jbc.271.28.16773 |
0.529 |
|
| 1996 |
Shimizu M, Gellibolian R, Oostra BA, Wells RD. Cloning, characterization and properties of plasmids containing CGG triplet repeats from the FMR-1 gene. Journal of Molecular Biology. 258: 614-26. PMID 8636996 DOI: 10.1006/Jmbi.1996.0273 |
0.449 |
|
| 1996 |
Kang S, Ohshima K, Jaworski A, Wells RD. CTG triplet repeats from the myotonic dystrophy gene are expanded in Escherichia coli distal to the replication origin as a single large event. Journal of Molecular Biology. 258: 543-7. PMID 8636989 DOI: 10.1006/Jmbi.1996.0266 |
0.4 |
|
| 1996 |
Ohshima K, Kang S, Wells RD. CTG triplet repeats from human hereditary diseases are dominant genetic expansion products in Escherichia coli. The Journal of Biological Chemistry. 271: 1853-6. PMID 8567629 DOI: 10.1074/Jbc.271.4.1853 |
0.444 |
|
| 1995 |
Amirhaeri S, Wohlrab F, Wells RD. Differential effects of simple repeating DNA sequences on gene expression from the SV40 early promoter. The Journal of Biological Chemistry. 270: 3313-9. PMID 7852417 DOI: 10.1074/Jbc.270.7.3313 |
0.355 |
|
| 1995 |
Kang S, Jaworski A, Ohshima K, Wells RD. Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli. Nature Genetics. 10: 213-8. PMID 7663518 DOI: 10.1038/Ng0695-213 |
0.427 |
|
| 1995 |
Kang S, Ohshima K, Shimizu M, Amirhaeri S, Wells RD. Pausing of DNA synthesis in vitro at specific loci in CTG and CGG triplet repeats from human hereditary disease genes. The Journal of Biological Chemistry. 270: 27014-21. PMID 7592950 DOI: 10.1074/Jbc.270.45.27014 |
0.573 |
|
| 1995 |
Bacolla A, Ulrich MJ, Larson JE, Ley TJ, Wells RD. An intramolecular triplex in the human gamma-globin 5'-flanking region is altered by point mutations associated with hereditary persistence of fetal hemoglobin. The Journal of Biological Chemistry. 270: 24556-63. PMID 7592674 DOI: 10.1074/Jbc.270.41.24556 |
0.345 |
|
| 1995 |
Jaworski A, Rosche WA, Gellibolian R, Kang S, Shimizu M, Bowater RP, Sinden RR, Wells RD. Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases. Proceedings of the National Academy of Sciences of the United States of America. 92: 11019-23. PMID 7479928 DOI: 10.1073/Pnas.92.24.11019 |
0.524 |
|
| 1994 |
Kang S, Wells RD. Zinc destabilizes DNA Watson-Crick pairs at AGCT. The Journal of Biological Chemistry. 269: 9528-32. PMID 8144538 |
0.411 |
|
| 1994 |
Wang YH, Amirhaeri S, Kang S, Wells RD, Griffith JD. Preferential nucleosome assembly at DNA triplet repeats from the myotonic dystrophy gene. Science (New York, N.Y.). 265: 669-71. PMID 8036515 DOI: 10.1126/Science.8036515 |
0.409 |
|
| 1994 |
Lukomski S, Wells RD. Left-handed Z-DNA and in vivo supercoil density in the Escherichia coli chromosome. Proceedings of the National Academy of Sciences of the United States of America. 91: 9980-4. PMID 7937930 DOI: 10.1073/pnas.91.21.9980 |
0.413 |
|
| 1992 |
Rahmouni AR, Wells RD. Direct evidence for the effect of transcription on local DNA supercoiling in vivo Journal of Molecular Biology. 223: 131-144. PMID 1731065 DOI: 10.1016/0022-2836(92)90721-U |
0.43 |
|
| 1992 |
Panyutin IG, Wells RD. Nodule DNA in the (GA)37·(CT)37 insert in superhelical plasmids Journal of Biological Chemistry. 267: 5495-5501. PMID 1544923 |
0.338 |
|
| 1992 |
Kang S, Wohlrab F, Wells RD. GC-rich flanking tracts decrease the kinetics of intramolecular DNA triplex formation Journal of Biological Chemistry. 267: 19435-19442. PMID 1527063 |
0.458 |
|
| 1992 |
Sinden RR, Wells RD. DNA structure, mutations, and human genetic disease. Current Opinion in Biotechnology. 3: 612-22. PMID 1369117 DOI: 10.1016/0958-1669(92)90005-4 |
0.537 |
|
| 1992 |
Hartman DA, Kuo SR, Broker TR, Chow LT, Wells RD. Intermolecular triplex formation distorts the DNA duplex in the regulatory region of human papillomavirus type-11. The Journal of Biological Chemistry. 267: 5488-94. PMID 1312091 |
0.435 |
|
| 1991 |
Venditti S, Wells RD. A DNA conformational alteration induced by a neighboring oligopurine tract on GAATTA enables nicking by EcoRI Journal of Biological Chemistry. 266: 16786-16790. PMID 1885606 |
0.347 |
|
| 1991 |
Jaworski A, Higgins NP, Wells RD, Zacharias W. Topoisomerase mutants and physiological conditions control supercoiling and Z-DNA formation in vivo Journal of Biological Chemistry. 266: 2576-2581. PMID 1846630 |
0.431 |
|
| 1991 |
Wohlrab F, Chatterjee S, Wells RD. The herpes simplex virus 1 segment inversion site is specifically cleaved by a virus-induced nuclear endonuclease Proceedings of the National Academy of Sciences of the United States of America. 88: 6432-6436. PMID 1650468 DOI: 10.1073/Pnas.88.15.6432 |
0.36 |
|
| 1990 |
Wells RD. Multiple non-B-DNA conformations of polypurine-polypyrimidine sequences in plasmids Biochemistry ®. 29: 4704-4713. PMID 2372553 DOI: 10.1021/Bi00471A027 |
0.474 |
|
| 1990 |
Hanvey JC, Shimizu M, Wells RD. Site-specific inhibition of EcoRI restriction/modification enzymes by a DNA triple helix Nucleic Acids Research. 18: 157-161. PMID 2308821 DOI: 10.1093/nar/18.1.157 |
0.385 |
|
| 1990 |
Bianchi A, Wells RD, Heintz NH, Caddle MS. Sequences near the origin of replication of the DHFR locus of Chinese hamster ovary cells adopt left-handed Z-DNA and triplex structures. The Journal of Biological Chemistry. 265: 21789-96. PMID 2254331 |
0.407 |
|
| 1990 |
Rajagopalan M, Rahmouni AR, Wells RD. Flanking AT-rich tracts cause a structural distortion in Z-DNA in plasmids Journal of Biological Chemistry. 265: 17294-17299. PMID 2211626 |
0.38 |
|
| 1990 |
Zacharias W, Jaworski A, Wells RD. Cytosine methylation enhances Z-DNA formation in vivo Journal of Bacteriology. 172: 3278-3283. PMID 2188955 DOI: 10.1128/Jb.172.6.3278-3283.1990 |
0.474 |
|
| 1990 |
Negishi K, Yamashita T, Zacharias W, Wells RD, Bessho T, Hayatsu H. Probing salt-induced and supercoiling-induced B-Z junctions in DNA by bisulfitemethoxyamine Nucleic Acids Symposium Series. 109-110. PMID 2101885 |
0.404 |
|
| 1990 |
Weinreb A, Collier DA, Birshtein BK, Wells RD. Left-handed Z-DNA and intramolecular triplex formation at the site of an unequal sister chromatid exchange. Journal of Biological Chemistry. 265: 1352-1359. DOI: 10.1016/s0021-9258(19)40021-5 |
0.362 |
|
| 1989 |
Blaho JA, Wells RD. Left-handed Z-DNA and genetic recombination Progress in Nucleic Acid Research and Molecular Biology. 37: 107-126. PMID 2672108 DOI: 10.1016/S0079-6603(08)60696-0 |
0.551 |
|
| 1989 |
Jaworski A, Blaho JA, Larson JE, Shimizu M, Wells RD. Tetracycline promoter mutations decrease non-B DNA structural transitions, negative linking differences and deletions in recombinant plasmids in Escherichia coli Journal of Molecular Biology. 207: 513-526. PMID 2547968 DOI: 10.1016/0022-2836(89)90461-0 |
0.547 |
|
| 1988 |
Hanvey JC, Shimizu M, Wells RD. Intramolecular DNA triplexes in supercoiled plasmids. Proceedings of the National Academy of Sciences of the United States of America. 85: 6292-6. PMID 3413097 DOI: 10.1073/Pnas.85.17.6292 |
0.529 |
|
| 1988 |
Zacharias W, Caserta M, O'Connor TR, Larson JE, Wells RD. Cytosine methylation as an effector of right-handed to left-handed DNA structural transitions Gene. 74: 221-224. PMID 3266857 DOI: 10.1016/0378-1119(88)90291-0 |
0.482 |
|
| 1988 |
Jaworski A, Zacharias W, Hsieh WT, Blaho JA, Larson JE, Wells RD. In vivo existence of left-handed DNA. Gene. 74: 215-20. PMID 3248726 DOI: 10.1016/0378-1119(88)90290-9 |
0.489 |
|
| 1988 |
Zacharias W, Jaworski A, Larson JE, Wells RD. The B- to Z-DNA equilibrium in vivo is perturbed by biological processes Proceedings of the National Academy of Sciences of the United States of America. 85: 7069-7073. PMID 3050986 DOI: 10.1073/Pnas.85.19.7069 |
0.469 |
|
| 1988 |
McLean MJ, Wells RD. The role of sequence in the stabilization of left-handed DNA helices in vitro and in vivo Bba - Gene Structure and Expression. 950: 243-254. PMID 3048405 DOI: 10.1016/0167-4781(88)90120-0 |
0.503 |
|
| 1988 |
Amirhaeri S, Wohlrab F, Major EO, Wells RD. Unusual DNA structure in the regulatory region of the human papovavirus JC virus. Journal of Virology. 62: 922-31. PMID 2828687 DOI: 10.1128/Jvi.62.3.922-931.1988 |
0.498 |
|
| 1988 |
Wells RD, Collier DA, Hanvey JC, Shimizu M, Wohlrab F. The chemistry and biology of unusual DNA structures adopted by oligopurine.oligopyrimidine sequences. The Faseb Journal. 2: 2939-2949. DOI: 10.1096/Fasebj.2.14.3053307 |
0.549 |
|
| 1988 |
Hanvey JC, Klysik J, Wells RD. Influence of DNA sequence on the formation of non-B right-handed helices in oligopurine.oligopyrimidine inserts in plasmids. Journal of Biological Chemistry. 263: 7386-7396. DOI: 10.1016/s0021-9258(18)68654-5 |
0.415 |
|
| 1988 |
McLean MJ, Lee JW, Wells RD. Characteristics of Z-DNA helices formed by imperfect (purine-pyrimidine) sequences in plasmids. Journal of Biological Chemistry. 263: 7378-7385. DOI: 10.1016/s0021-9258(18)68653-3 |
0.468 |
|
| 1988 |
McLean MJ, Wells RD. The role of DNA sequence in the formation of Z-DNA versus cruciforms in plasmids. Journal of Biological Chemistry. 263: 7370-7377. DOI: 10.1016/s0021-9258(18)68652-1 |
0.48 |
|
| 1988 |
Blaho JA, Larson JE, McLean MJ, Wells RD. Multiple DNA secondary structures in perfect inverted repeat inserts in plasmids. Right-handed B-DNA, cruciforms, and left-handed Z-DNA. Journal of Biological Chemistry. 263: 14446-14455. DOI: 10.1016/s0021-9258(18)68240-7 |
0.456 |
|
| 1987 |
Porschke D, Zacharias W, Wells RD. B-Z DNA junctions are neither highly flexible nor strongly bent Biopolymers - Peptide Science Section. 26: 1971-1974. PMID 3689878 DOI: 10.1002/Bip.360261111 |
0.478 |
|
| 1987 |
Jaworski A, Hsieh WT, Blaho JA, Larson JE, Wells RD. Left-handed DNA in vivo. Science (New York, N.Y.). 238: 773-7. PMID 3313728 DOI: 10.1126/Science.3313728 |
0.427 |
|
| 1987 |
Mclean MJ, Larson JE, Wohlrab F, Wells RD. Reaction conditions affect the specificity of bromoacetaidehyde as a probe for DNA cruciforms and B - Z junctions Nucleic Acids Research. 15: 6917-6935. PMID 2821485 DOI: 10.1093/Nar/15.17.6917 |
0.392 |
|
| 1987 |
Whitson PA, Hsieh WT, Wells RD, Matthews KS. Influence of supercoiling and sequence context on operator DNA binding with lac repressor. Journal of Biological Chemistry. 262: 14592-14599. DOI: 10.1016/s0021-9258(18)47837-4 |
0.369 |
|
| 1987 |
Hsieh WT, Wells RD. Influence of negative supercoiling and of the proximity of left-handed Z-DNA on the Escherichia coli lactose repressor-operator interaction. Journal of Biological Chemistry. 262: 14576-14582. DOI: 10.1016/s0021-9258(18)47835-0 |
0.323 |
|
| 1987 |
Blaho J, Wells R. Left-handed Z-DNA binding by the recA protein of Escherichia coli. Journal of Biological Chemistry. 262: 6082-6088. DOI: 10.1016/s0021-9258(18)45540-8 |
0.328 |
|
| 1986 |
Lambert PF, Waring DA, Wells RD, Reznikoff WS. DNA requirements at the bacteriophage G4 origin of complementary-strand DNA synthesis. Journal of Virology. 58: 450-8. PMID 3754589 DOI: 10.1128/Jvi.58.2.450-458.1986 |
0.542 |
|
| 1986 |
McLean MJ, Blaho JA, Kilpatrick MW, Wells RD. Consecutive A·T pairs can adopt a left-handed DNA structure Proceedings of the National Academy of Sciences of the United States of America. 83: 5884-5888. PMID 3016726 DOI: 10.1073/Pnas.83.16.5884 |
0.499 |
|
| 1986 |
Fong D, Calhoun DH, Hsieh WT, Lee B, Wells RD. Isolation of a cDNA clone for the human lysosomal proteinase cathepsin B. Proceedings of the National Academy of Sciences of the United States of America. 83: 2909-13. PMID 3010323 |
0.308 |
|
| 1986 |
Galazka G, Palecek E, Wells RD, Klysik J. Site-specific OsO4 modification of the B-Z junctions formed at the (dA-dC)32 region in supercoiled DNA. Journal of Biological Chemistry. 261: 7093-7098. DOI: 10.1016/s0021-9258(19)62725-0 |
0.339 |
|
| 1986 |
Kilpatrick MW, Torri A, Kang DS, Engler JA, Wells RD. Unusual DNA structures in the adenovirus genome. Journal of Biological Chemistry. 261: 11350-11354. DOI: 10.1016/s0021-9258(18)67390-9 |
0.358 |
|
| 1986 |
Kitchin PA, Klein VA, Ryan KA, Gann KL, Rauch CA, Kang DS, Wells RD, Englund PT. A highly bent fragment of Crithidia fasciculata kinetoplast DNA. Journal of Biological Chemistry. 261: 11302-11309. DOI: 10.1016/s0021-9258(18)67383-1 |
0.463 |
|
| 1985 |
Wells RD. Biophysics of left-handed Z-DNA Advances in Biophysics. 20: 31-38. PMID 3010659 DOI: 10.1016/0065-227X(85)90029-2 |
0.527 |
|
| 1985 |
Kang DS, Harvey SC, Wells RD. Diepoxybutane forms a monoadduct with B-form (dG-dC)n.(dG-dC)n and a crosslinked diadduct with the left-handed Z-form. Nucleic Acids Research. 13: 5645-56. PMID 2994006 DOI: 10.1093/Nar/13.15.5645 |
0.44 |
|
| 1985 |
Kang DS, Wells RD. B-Z DNA junctions contain few, if any, nonpaired bases at physiological superhelical densities. Journal of Biological Chemistry. 260: 7783-7790. DOI: 10.1016/s0021-9258(17)39675-8 |
0.355 |
|
| 1984 |
Singleton CK, Kilpatrick MW, Wells RD. S1 nuclease recognizes DNA conformational junctions between left-handed helical (dT-dG n. dC-dA)n and contiguous right-handed sequences. The Journal of Biological Chemistry. 259: 1963-7. PMID 6319416 |
0.537 |
|
| 1984 |
Kilpatrick MW, Klysik J, Singleton CK, Zarling DA, Jovin TM, Hanau LH, Erlanger BF, Wells RD. Intervening sequences in human fetal globin genes adopt left-handed Z helices. The Journal of Biological Chemistry. 259: 7268-74. PMID 6202693 |
0.596 |
|
| 1984 |
Wells RD. High-performance liquid chromatography of DNA Journal of Chromatography B: Biomedical Sciences and Applications. 336: 3-14. PMID 6098596 DOI: 10.1016/S0378-4347(00)85125-7 |
0.417 |
|
| 1984 |
Unger B, Klock G, Hillen W, Wells RD. Nucleotide sequence of the repressor gene of the RA1 tetracycline resistance determinant: Structural and functional comparison with three related tet repressor genes Nucleic Acids Research. 12: 7693-7703. PMID 6093049 DOI: 10.1093/Nar/12.20.7693 |
0.337 |
|
| 1984 |
Zacharias W, Larson JE, Kilpatrick MW, Wells RD. Hhal methylase and restriction endonuclease as probes for B to Z DNA conformational changes in d(GCGC) sequences Nucleic Acids Research. 12: 7677-7692. PMID 6093048 DOI: 10.1093/nar/12.20.7677 |
0.309 |
|
| 1984 |
Marini JC, Effron PN, Goodman TC, Singleton CK, Wells RD, Wartell RM, Englund PT. Physical characterization of a kinetoplast DNA fragment with unusual properties. The Journal of Biological Chemistry. 259: 8974-9. PMID 6086618 |
0.564 |
|
| 1983 |
Zacharias W, Martin JC, Wells RD. Condensed form of (dG-dC)n·(dG-dC)n as an intermediate between the B- and Z-type conformations induced by sodium acetate Biochemistry. 22: 2398-2405. PMID 6860635 DOI: 10.1021/Bi00279A015 |
0.422 |
|
| 1983 |
Wells RD, Brennan R, Chapman KA, Goodman TC, Hart PA, Hillen W, Kellogg DR, Kilpatrick MW, Klein RD, Klysik J, Lambert PF, Larson JE, Miglietta JJ, Neuendorf SK, O'Connor TR, et al. Left-handed DNA helices, supercoiling, and the B-Z junction. Cold Spring Harbor Symposia On Quantitative Biology. 47: 77-84. PMID 6345066 DOI: 10.1101/Sqb.1983.047.01.010 |
0.645 |
|
| 1983 |
Klysik J, Stirdivant SM, Singleton CK, Zacharias W, Wells RD. Effects of 5 cytosine methylation on the B-Z transition in DNA restriction fragments and recombinant plasmids. Journal of Molecular Biology. 168: 51-71. PMID 6308270 DOI: 10.1016/S0022-2836(83)80322-2 |
0.649 |
|
| 1983 |
Kilpatrick MW, Wei CF, Gray HB, Wells RD. BAL 31 nuclease as a probe in concentrated salt for the B-Z DNA junction. Nucleic Acids Research. 11: 3811-22. PMID 6304643 DOI: 10.1093/Nar/11.11.3811 |
0.517 |
|
| 1983 |
Singleton CK, Klysik J, Wells RD. Conformational flexibility of junctions between contiguous B- and Z-DNAs in supercoiled plasmids. Proceedings of the National Academy of Sciences of the United States of America. 80: 2447-51. PMID 6302683 DOI: 10.1073/Pnas.80.9.2447 |
0.654 |
|
| 1983 |
O'Connor T, Kilpatrick MW, Klysik J, Larson JE, Martin JC, Singleton CK, Stirdivant SM, Zacharias W, Wells RD. Left-handed Z-DNA helices in polymers, restriction fragments, and recombinant plasmids. Journal of Biomolecular Structure & Dynamics. 1: 999-1009. PMID 6101088 DOI: 10.1080/07391102.1983.10507498 |
0.652 |
|
| 1983 |
Wartell RM, Harrell JT, Zacharias W, Wells RD. Raman spectroscopy study of the B-Z transition in (dG-dC)n.(dG-dC)n and a DNA restriction fragment. Journal of Biomolecular Structure & Dynamics. 1: 83-96. PMID 6101084 DOI: 10.1080/07391102.1983.10507427 |
0.45 |
|
| 1982 |
Wartell RM, Klysik J, Hillen W, Wells RD. Junction between Z and B conformations in a DNA restriction fragment: evaluation by Raman spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 79: 2549-53. PMID 7045865 DOI: 10.1073/Pnas.79.8.2549 |
0.434 |
|
| 1982 |
Diekmann S, Hillen W, Morgeneyer B, Wells RD, Pörschke D. Orientation relaxation of DNA restriction fragments and the internal mobility of the double helix. Biophysical Chemistry. 15: 263-70. PMID 6288135 DOI: 10.1016/0301-4622(82)80009-4 |
0.389 |
|
| 1982 |
Singleton CK, Wells RD. The facile generation of covalently closed, circular DNAs with defined negative superhelical densities. Analytical Biochemistry. 122: 253-7. PMID 6287878 DOI: 10.1016/0003-2697(82)90277-9 |
0.615 |
|
| 1982 |
Singleton CK, Klysik J, Stirdivant SM, Wells RD. Left-handed Z-DNA is induced by supercoiling in physiological ionic conditions. Nature. 299: 312-6. PMID 6287292 DOI: 10.1038/299312A0 |
0.657 |
|
| 1982 |
Diekmann S, Hillen W, Jung M, Wells RD, Pörschke D. Electric properties and structure of DNA-restriction fragments from measurements of the electric dichroism. Biophysical Chemistry. 15: 157-67. PMID 6284266 DOI: 10.1016/0301-4622(82)80028-8 |
0.406 |
|
| 1982 |
Singleton CK, Wells RD. Relationship between superhelical density and cruciform formation in plasmid pVH51. The Journal of Biological Chemistry. 257: 6292-5. PMID 6281266 |
0.476 |
|
| 1982 |
Stirdivant SM, Kłysik J, Wells RD. Energetic and structural inter-relationship between DNA supercoiling and the right- to left-handed Z helix transitions in recombinant plasmids. Journal of Biological Chemistry. 257: 10159-10165. DOI: 10.1016/s0021-9258(18)33998-x |
0.358 |
|
| 1982 |
Kłysik J, Stirdivant SM, Wells RD. Left-handed DNA. Cloning, characterization, and instability of inserts containing different lengths of (dC-dG) in Escherichia coli. Journal of Biological Chemistry. 257: 10152-10158. DOI: 10.1016/s0021-9258(18)33997-8 |
0.402 |
|
| 1982 |
Goodman TC, Klein RD, Wells RD. Effects of neighboring DNA homopolymers on the biochemical and physical properties of the Escherichia coli lactose promoter. III. High resolution thermal denaturation and circular dichroism studies. Journal of Biological Chemistry. 257: 12970-12978. DOI: 10.1016/s0021-9258(18)33610-x |
0.33 |
|
| 1982 |
Klein RD, Wells RD. Effects of Neighboring DNA homopolymers on the biochemical and physical properties of the Escherichia coli lactose promoter. II. In vitro transcription analyses. Journal of Biological Chemistry. 257: 12962-12969. DOI: 10.1016/s0021-9258(18)33609-3 |
0.313 |
|
| 1982 |
Klein RD, Wells RD. Effects of neighboring DNA homopolymers on the biochemical and physical properties of the Escherichia coli lactose promoter. I. Cloning and characterization studies. Journal of Biological Chemistry. 257: 12954-12961. DOI: 10.1016/s0021-9258(18)33608-1 |
0.379 |
|
| 1981 |
Panayotatos N, Wells RD. Cruciform structures in supercoiled DNA Nature. 289: 466-470. PMID 7464915 DOI: 10.1038/289466A0 |
0.493 |
|
| 1981 |
Hillen W, Goodman TC, Wells RD. Circular dichroism spectra of twelve short DNA restriction fragments of known sequence: A comparison of measured and calculated spectra Nucleic Acids Research. 9: 3029-3045. PMID 6269070 DOI: 10.1093/Nar/9.13.3029 |
0.382 |
|
| 1981 |
Hillen W, Klein RD, Wells RD. Preparation of milligram amounts of 21 deoxyribonucleic acid restriction fragments. Biochemistry. 20: 3748-56. PMID 6268143 DOI: 10.1021/Bi00516A013 |
0.502 |
|
| 1981 |
Kłysik J, Stirdivant SM, Larson JE, Hart PA, Wells RD. Left-handed DNA in restriction fragments and a recombinant plasmid Nature. 290: 672-677. PMID 6261149 DOI: 10.1038/290672A0 |
0.506 |
|
| 1981 |
Hillen W, Goodman TC, Wells RD. Salt dependence and thermodynamic interpretation of the thermal denaturation of small DNA restriction fragments Nucleic Acids Research. 9: 415-436. PMID 6259627 DOI: 10.1093/Nar/9.2.415 |
0.376 |
|
| 1981 |
Wells RD, Klein RD, Singleton CK. 10 Type II Restriction Enzymes Enzymes. 14: 157-191. DOI: 10.1016/S1874-6047(08)60336-4 |
0.591 |
|
| 1980 |
Wells RD, Goodman TC, Hillen W, Horn GT, Klein RD, Larson JE, Müller UR, Neuendorf SK, Panayotatos N, Stirdivant SM. DNA Structure and Gene Regulation Progress in Nucleic Acid Research and Molecular Biology. 24: 167-267. PMID 7005967 DOI: 10.1016/S0079-6603(08)60674-1 |
0.529 |
|
| 1980 |
Müller UR, Wells RD. Intercistronic regions in øX174 DNA. I. Construction of mutants with altered intercistronic regions between genes J and F Journal of Molecular Biology. 141: 1-24. PMID 6448926 DOI: 10.1016/S0022-2836(80)80026-X |
0.468 |
|
| 1980 |
Klein RD, Selsing E, Wells RD. A rapid microscale technique for isolation of recombinant plasmid DNA suitable for restriction enzyme analysis Plasmid. 3: 88-91. PMID 6278527 DOI: 10.1016/S0147-619X(80)90037-2 |
0.476 |
|
| 1980 |
Early TA, Kearns DR, Hillen W, Wells RD. A 300 MHz and 600 MHz proton NMR study of a 12 base pair restriction fragment: investigation of structure by relaxation measurements. Nucleic Acids Research. 8: 5795-812. PMID 6258152 DOI: 10.1093/Nar/8.23.5795 |
0.363 |
|
| 1980 |
Hillen W, Wells RD. Circular dichroism studies of the B→A conformational transition in seven small DNA restriction fragments containing the Escherichia coti lactose control region Nucleic Acids Research. 8: 5427-5444. PMID 6258144 DOI: 10.1093/Nar/8.22.5427 |
0.466 |
|
| 1980 |
Müller UR, Wells RD. Intercistronic regions in øX174 DNA. II. Biochemical and biological analysis of mutants with altered intercistronic regions between genes J and F Journal of Molecular Biology. 141: 25-41. PMID 6253647 DOI: 10.1016/S0022-2836(80)80027-1 |
0.363 |
|
| 1980 |
Wells RD, Hardies SC, Horn GT, Klein B, Larson JE, Neuendorf SK, Panayotatos N, Patient RK, Selsing E. [41] RPC-5 Column chromatography for the isolation of DNA fragments Methods in Enzymology. 65: 327-347. PMID 6246356 DOI: 10.1016/S0076-6879(80)65043-5 |
0.415 |
|
| 1979 |
Panayotatos N, Wells RD. Identification, cloning and characterization of three late promoters at 14.6, 14.8 and 15.9% of T7 DNA Journal of Molecular Biology. 135: 91-109. PMID 529292 DOI: 10.1016/0022-2836(79)90342-5 |
0.489 |
|
| 1979 |
Selsing E, Wells RD. Preparation of triple-block DNA polymers using recombinant DNA techniques Nucleic Acids Research. 6: 3025-3040. PMID 493133 DOI: 10.1093/Nar/6.9.3025 |
0.545 |
|
| 1979 |
Loucks E, Chaconas G, Blakesley RW, Wells RD, van de Sande JH. Antibiotic induced ekctrophoretic mobility shifts of DNA restriction fragments Nucleic Acids Research. 6: 1869-1879. PMID 450716 DOI: 10.1093/Nar/6.5.1869 |
0.732 |
|
| 1979 |
Hardies SC, Wells RD. Preparation and characterization of large amounts of restriction fragments containing the E. coli lac control elements Gene. 7: 1-14. PMID 387526 DOI: 10.1016/0378-1119(79)90039-8 |
0.398 |
|
| 1979 |
Panayotatos N, Wells RD. Recognition and initiation site for four late promoters of phage T7 is a 22-base pair DNA sequence Nature. 280: 35-39. DOI: 10.1038/280035A0 |
0.396 |
|
| 1979 |
Panayotatos N, Wells RD. Cloning and localization of the in vitro functional origin of replication of bacteriophage T7 DNA. Journal of Biological Chemistry. 254: 5555-5561. DOI: 10.1016/s0021-9258(18)50631-1 |
0.359 |
|
| 1979 |
Patient RK, Hardies SC, Larson JE, Inman RB, Maquat LE, Wells RD. Influence of A-T content on the fractionation of DNA restriction fragments by RPC-5 column chromatography. Journal of Biological Chemistry. 254: 5548-5554. DOI: 10.1016/s0021-9258(18)50630-x |
0.333 |
|
| 1979 |
Larson JE, Hardies SC, Patient RK, Wells RD. Factors influencing fractionation of DNA restriction fragments by RPC-5 column chromatography. Journal of Biological Chemistry. 254: 5535-5541. DOI: 10.1016/s0021-9258(18)50628-1 |
0.355 |
|
| 1979 |
Hardies SC, Patient RK, Klein RD, Ho F, Reznikoff WS, Wells RD. Construction and mapping of recombinant plasmids used for the preparation of DNA fragments containing the Escherichia coli lactose operator and promoter. Journal of Biological Chemistry. 254: 5527-5534. DOI: 10.1016/s0021-9258(18)50627-x |
0.338 |
|
| 1979 |
Selsing E, Wells RD, Alden CJ, Arnott S. Bent DNA: visualization of a base-paired and stacked A-B conformational junction. Journal of Biological Chemistry. 254: 5417-5422. DOI: 10.1016/s0021-9258(18)50612-8 |
0.317 |
|
| 1979 |
Selsing E, Wells RD. Polynucleotide block polymers consisting of a DNA.RNA hybrid joined to a DNA.DNA duplex. Synthesis and characterization of dGn.rCidCk duplexes. Journal of Biological Chemistry. 254: 5410-5416. DOI: 10.1016/s0021-9258(18)50611-6 |
0.444 |
|
| 1978 |
Selsing E, Wells RD, Early TA, Kearns DR. Two contiguous conformations in a nucleic acid duplex. Nature. 275: 249-50. PMID 692703 DOI: 10.1038/275249A0 |
0.551 |
|
| 1977 |
Jensen KF, Nes IF, Wells RD. Iodination as a probe for small regions of disrupted secondary structure in double-stranded DNAs. Nucleic Acids Research. 3: 3143-55. PMID 1087408 DOI: 10.1093/Nar/3.11.3143 |
0.569 |
|
| 1977 |
Chan HW, Dodgson JB, Wells RD. Influence of DNA structure on the lactose operator-repressor interaction. Biochemistry. 16: 2356-66. PMID 861213 DOI: 10.1021/Bi00630A008 |
0.682 |
|
| 1977 |
Early TA, Kearns DR, Burd JF, Larson JE, Wells RD. High resolution proton nuclear magnetic resonance investigation of the structural and dynamic properties of d(C15A15)-d(T15G15). Biochemistry. 16: 541-51. PMID 836800 DOI: 10.1021/Bi00622A031 |
0.393 |
|
| 1977 |
Wells RD, Blakesley RW, Hardies SC, Horn GT, Larson JE, Selsing E, Burd JF, Chan HW, Dodgson JB, Jensen KF, Nes IF, Wartell RM. The role of DNA structure in genetic regulation. Crc Critical Reviews in Biochemistry. 4: 305-40. PMID 319949 DOI: 10.3109/10409237709102561 |
0.695 |
|
| 1977 |
Dodgson JB, Wells RD. Action of single-strand specific nucleases on model DNA heteroduplexes of defined size and sequence Biochemistry. 16: 2374-2379. PMID 301043 DOI: 10.1021/Bi00630A010 |
0.715 |
|
| 1977 |
Dodgson JB, Wells RD. Synthesis and thermal melting behavior of oligomer·polymer complexes containing defined lengths of mismatched dA·dG and dG·dG nucleotides Biochemistry. 16: 2367-2374. PMID 301042 DOI: 10.1021/Bi00630A009 |
0.71 |
|
| 1977 |
Jones BB, Chan H, Rothstein S, Wells RD, Reznikoff WS. RNA polymerase binding sites in λ plac5 DNA Proceedings of the National Academy of Sciences of the United States of America. 74: 4914-4918. PMID 270725 DOI: 10.1073/Pnas.74.11.4914 |
0.346 |
|
| 1977 |
Blakesley RW, Dodgson JB, Nes IF, Wells RD. Duplex regions in "single-stranded" phiX174 DNA are cleaved by a restriction endonuclease from Haemophilus aegyptius. Journal of Biological Chemistry. 252: 7300-7306. DOI: 10.1016/s0021-9258(19)66969-3 |
0.719 |
|
| 1976 |
Hardies SC, Wells RD. Preparative fractionation of DNA restriction fragments by reversed phase column chromatography Proceedings of the National Academy of Sciences of the United States of America. 73: 3117-3121. PMID 1067607 DOI: 10.1073/Pnas.73.9.3117 |
0.442 |
|
| 1976 |
Ryan MJ, Wells RD. Coumermycin A1: A preferential inhibitor of replicative DNA synthesis in Escherichia coli. I. In vivo characterization. Biochemistry. 15: 3769-3777. PMID 782523 DOI: 10.1021/Bi00662A021 |
0.463 |
|
| 1976 |
Dodgson JB, Nes IF, Porter BW, Wells RD. Two new genetic assays for noninfectious fragments of phiX174 DNA. Virology. 69: 782-5. PMID 769307 DOI: 10.1016/0042-6822(76)90506-7 |
0.734 |
|
| 1975 |
Tamblyn TM, Wells RD. Comparative ability of RNA and DNA to prime DNA synthesis in vitro: Role of sequence, sugar, and structure of template • primer Biochemistry. 14: 1412-1425. PMID 1092334 DOI: 10.1021/Bi00678A011 |
0.462 |
|
| 1975 |
Blakesley RW, Wells RD. 'Single-stranded' DNA from φX174 and M13 is cleaved by certain restriction endonucleases Nature. 257: 421-422. PMID 809717 DOI: 10.1038/257421A0 |
0.543 |
|
| 1975 |
Burd JF, Wartell RM, Dodgson JB, Wells RD. Transmission of stability (telestability) in deoxyribonucleic acid. Physical and enzymatic studies on the duplex block polymer d(C15A15) - d(T15G15). Journal of Biological Chemistry. 250: 5109-5113. DOI: 10.1016/s0021-9258(19)41284-2 |
0.549 |
|
| 1974 |
Chan HW, Wells RD. Structural uniqueness of lactose operator Nature. 252: 205-209. PMID 4607802 DOI: 10.1038/252205A0 |
0.434 |
|
| 1974 |
Brewer LC, Wells RD. Mechanistic independence of avian myeloblastosis virus DNA polymerase and ribonuclease H Journal of Virology. 14: 1494-1502. PMID 4372408 DOI: 10.1128/Jvi.14.6.1494-1502.1974 |
0.459 |
|
| 1973 |
Flugel RM, Rapp U, Wells RD. RNA DNA covalent bonds between the RNA primers and the DNA products formed by RNA tumor virus DNA polymerase Journal of Virology. 12: 1491-1502. PMID 4357517 DOI: 10.1128/Jvi.12.6.1491-1502.1973 |
0.378 |
|
| 1972 |
Grant RC, Kodama M, Wells RD. Enzymatic and physical studies on (dI-dC)n·(dI-dC)n and (dG-dC)n·(dG-dC)n Biochemistry. 11: 805-815. PMID 4551095 DOI: 10.1021/Bi00755A020 |
0.419 |
|
| 1972 |
Riggs AD, Lin S, Wells RD. Lac repressor binding to synthetic DNAs of defined nucleotide sequence Proceedings of the National Academy of Sciences of the United States of America. 69: 761-764. PMID 4501591 DOI: 10.1073/PNAS.69.3.761 |
0.41 |
|
| 1972 |
Flügel RM, Wells RD. Nucleotides at the RNA-DNA covalent bonds formed in the endogenous reaction by the avian myeloblastosis virus DNA polymerase Virology. 48: 394-401. PMID 4337028 DOI: 10.1016/0042-6822(72)90050-5 |
0.49 |
|
| 1971 |
Miller LK, Wells RD. Nucleoside diphosphokinase activity associated with DNA polymerases Proceedings of the National Academy of Sciences of the United States of America. 68: 2298-2302. PMID 4332252 DOI: 10.1073/Pnas.68.9.2298 |
0.532 |
|
| 1970 |
Wells RD, Larson JE, Grant RC, Shortle BE, Cantor CR. Physicochemical studies on polydeoxyribonucleotides containing defined repeating nucleotide sequences Journal of Molecular Biology. 54: 465-497. PMID 5492018 DOI: 10.1016/0022-2836(70)90121-X |
0.541 |
|
| 1970 |
Wells RD, Larson JE. Studies on the binding of actinomycin D to DNA and DNA model polymers Journal of Molecular Biology. 49: 319-342. PMID 5464945 DOI: 10.1016/0022-2836(70)90248-2 |
0.383 |
|
| 1970 |
Harwood SJ, Schendel PF, Miller LK, Wells RD. Dinucleotides as products of an exonucleolytic activity association with the Micrococcus luteus DNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 66: 595-602. PMID 5269226 DOI: 10.1073/Pnas.66.3.595 |
0.492 |
|
| 1970 |
Burd JF, Wells RD. Effect of incubation conditions on the nucleotide sequence of DNA products of unprimed DNA polymerase reactions Journal of Molecular Biology. 53: 435-459. PMID 4924007 DOI: 10.1016/0022-2836(70)90076-8 |
0.485 |
|
| 1970 |
Mitsui Y, Langridge R, Shortle BE, Cantor CR, Grant RC, Kodama M, Wells RD. Physical and enzymatic studies on poly d(I-C)-poly d(I-C), an unusual double-helical DNA. Nature. 228: 1166-9. PMID 4321098 DOI: 10.1038/2281166A0 |
0.338 |
|
| 1969 |
Kössel H, Büchi H, Jacob TM, Morgan AR, Narang SA, Ohtsuka E, Wells RD, Khorana HG. Synthese von codierenden Polynucleotiden repetierender Basensequenz Angewandte Chemie. 81: 336-337. DOI: 10.1002/Ange.19690810922 |
0.728 |
|
| 1968 |
Morgan AR, Wells RD. Specificity of the three-stranded complex formation between double-stranded DNA and single-stranded RNA containing repeating nucleotide sequences Journal of Molecular Biology. 37: 63-80. PMID 5760495 DOI: 10.1016/0022-2836(68)90073-9 |
0.616 |
|
| 1967 |
Wells RD, Blair JE. Studies on polynucleotides. LXXI. Sedimentation and buoyant density studies of some DNA-like polymers with repeating nucleotide sequences Journal of Molecular Biology. 27: 273-288. PMID 6048983 DOI: 10.1016/0022-2836(67)90020-4 |
0.381 |
|
| 1967 |
Morgan AR, Wells RD, Khorana HG. Studies on polynucleotides. LXXIV. Direct translation in vitro of single-stranded DNA-like polymers with repeating nucleotide sequences in the presence of neomycin B. Journal of Molecular Biology. 26: 477-97. PMID 5339796 DOI: 10.1016/0022-2836(67)90316-6 |
0.643 |
|
| 1967 |
Wells RD, Büchi H, Kössel H, Ohtsuka E, Khorana HG. Studies on polynucleotides. LXX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating tetranucleotide sequences. Journal of Molecular Biology. 27: 265-72. PMID 4862296 |
0.778 |
|
| 1967 |
Wells RD, Jacob TM, Narang SA, Khorana HG. Studies on polynucleotides. LXIX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating trinucleotide sequences. Journal of Molecular Biology. 27: 237-63. PMID 4860495 DOI: 10.1016/0022-2836(67)90018-6 |
0.754 |
|
| 1966 |
Morgan AR, Wells RD, Khorana HG. Studies on polynucleotides, lix. Further codon assignments from amino Acid incorporations directed by ribopolynucleotides containing repeating trinucleotide sequences. Proceedings of the National Academy of Sciences of the United States of America. 56: 1899-906. PMID 16591436 DOI: 10.1073/Pnas.56.6.1899 |
0.629 |
|
| 1966 |
Khorana HG, Büchi H, Ghosh H, Gupta N, Jacob TM, Kössel H, Morgan R, Narang SA, Ohtsuka E, Wells RD. Polynucleotide synthesis and the genetic code. Cold Spring Harbor Symposia On Quantitative Biology. 31: 39-49. PMID 5237635 DOI: 10.1101/Sqb.1966.031.01.010 |
0.626 |
|
| 1965 |
HOFMANN K, SCHMIECHEN R, SMITHERS MJ, WELLS RD, WOLMAN Y, ZANETTI G. STUDIES ON POLYPEPTIDES. XXXII. SYNTHETIC PEPTIDES RELATED TO THE N-TERMINUS OF BOVINE PANCREATIC RIBONUCLEASE A (POSITIONS 1-13). Journal of the American Chemical Society. 87: 640-4. PMID 14263389 |
0.379 |
|
| 1965 |
HOFMANN K, HAAS W, SMITHERS MJ, WELLS RD, WOLMAN Y, YANAIHARA N, ZANETTI G. STUDIES ON POLYPEPTIDES. XXX. SYNTHETIC PEPTIDES RELATED TO THE N-TERMINUS OF BOVINE PANCREATIC RIBONUCLEASE (POSITIONS 8-13). Journal of the American Chemical Society. 87: 620-31. PMID 14263387 |
0.379 |
|
| 1965 |
HOFMANN K, SCHMIECHEN R, WELLS RD, WOLMAN Y, YANAIHARA N. STUDIES ON POLYPEPTIDES. XXIX. SYNTHETIC PEPTIDES RELATED TO THE N-TERMINUS OF BOVINE PANCREATIC RIBONUCLEASE A (POSITIONS 1-7). Journal of the American Chemical Society. 87: 611-9. PMID 14263386 |
0.379 |
|
| 1965 |
Wells RD, Ohtsuka E, Khorana HG. Studies on polynucleotides. L. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: a new double-stranded DNA-like polymer containing repeating dinucleotide sequences. Journal of Molecular Biology. 14: 221-37. PMID 5327651 DOI: 10.1016/S0022-2836(65)80242-X |
0.613 |
|
| 1963 |
Hofmann K, Wells RD, Yajima H, Rosenthaler J. Studies on Polypeptides. XXVII. Elimination of the Methionine Residue as an Essential Functional Unit forin vivoAdrenocorticotropic Activity1-3 Journal of the American Chemical Society. 85: 1546-1547. DOI: 10.1021/Ja00893A042 |
0.385 |
|
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