Timothy L. Cover - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Microbiology Biology

222 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Caso GC, McClain MS, Erwin AL, Truelock MD, Campbell AM, Leasure CS, Nagel M, Schey KL, Lacy DB, Ohi MD, Cover TL. Functional properties of oligomeric and monomeric forms of VacA toxin. Infection and Immunity. IAI0034821. PMID 34543122 DOI: 10.1128/IAI.00348-21  1
2021 Harvey ML, Lin AS, Sun L, Koyama T, Shuman JHB, Loh JT, Scott Algood HM, Scholz MB, McClain MS, Cover TL. Enhanced fitness of a mutant in a murine model. Infection and Immunity. IAI0072520. PMID 34310886 DOI: 10.1128/IAI.00725-20  1
2021 Cover TL. Tracking bacterial effector protein delivery into host cells. Molecular Microbiology. PMID 34250669 DOI: 10.1111/mmi.14784  0.01
2021 Lo CH, Blot WJ, Teras LR, Visvanathan K, Le Marchand L, Haiman CA, Chen Y, Sesso HD, Wassertheil-Smoller S, Tinker LF, Peek RM, Potter JD, Cover TL, Zeleniuch-Jacquotte A, Berndt SI, et al. Prediagnostic antibody responses to Fusobacterium nucleatum proteins are not associated with risk of colorectal cancer in a large United States consortium. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 33737297 DOI: 10.1158/1055-9965.EPI-20-1471  1
2021 Loh JT, Shum MV, Jossart SDR, Campbell AM, Sawhney N, McDonald WH, Scholz MB, McClain MS, Forsyth MH, Cover TL. Delineation of the pH-responsive regulon controlled by the ArsRS two- component system. Infection and Immunity. PMID 33526561 DOI: 10.1128/IAI.00597-20  1
2021 Batcho EC, Miller S, Cover TL, McClain MS, Marasco C, Bell CS, Giorgio TD. Inertial-based Fluidic Platform for Rapid Isolation of Blood-borne Pathogens. Military Medicine. 186: 129-136. PMID 33499487 DOI: 10.1093/milmed/usaa442  1
2020 Dooyema SDR, Krishna US, Loh JT, Suarez G, Cover TL, Peek RM. Helicobacter pylori-induced TLR9 Activation and Injury are Associated with the Virulence-Associated Adhesin HopQ. The Journal of Infectious Diseases. PMID 33245103 DOI: 10.1093/infdis/jiaa730  1
2020 Epplein M, Le Marchand L, Cover TL, Song M, Blot WJ, Peek RM, Teras LR, Visvanathan K, Chen Y, Sesso HD, Zeleniuch-Jacquotte A, Berndt SI, Potter JD, Ryser MD, Haiman CA, et al. Association of Combined Sero-Positivity to and with Risk of Colorectal Cancer. Microorganisms. 8. PMID 33143263 DOI: 10.3390/microorganisms8111698  1
2020 Li P, Hu M, Wang C, Feng X, Zhao Z, Yang Y, Sahoo N, Gu M, Yang Y, Xiao S, Sah R, Cover TL, Chou J, Geha R, Benavides F, et al. LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses. Proceedings of the National Academy of Sciences of the United States of America. PMID 33139539 DOI: 10.1073/pnas.2016539117  0.01
2020 Sheedlo MJ, Chung JM, Sawhney N, Durie CL, Cover TL, Ohi MD, Lacy DB. Cryo-EM reveals species-specific components within the Cag type IV secretion system core complex. Elife. 9. PMID 32876048 DOI: 10.7554/Elife.59495  1
2020 Varga MG, Butt J, Blot WJ, Le Marchand L, Haiman CA, Chen Y, Wassertheil-Smoller S, Tinker LF, Peek RM, Potter JD, Cover TL, Hyslop T, Zeleniuch-Jacquotte A, Berndt SI, Hildesheim A, et al. Racial differences in Helicobacter pylori CagA sero-prevalence in a consortium of adult cohorts in the United States. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 32856604 DOI: 10.1158/1055-9965.Epi-20-0525  1
2020 Lin AS, McClain MS, Beckett AC, Caston RR, Harvey ML, Dixon BREA, Campbell AM, Shuman JHB, Sawhney N, Delgado AG, Loh JT, Piazuelo MB, Algood HMS, Cover TL. Temporal Control of the Helicobacter pylori Cag Type IV Secretion System in a Mongolian Gerbil Model of Gastric Carcinogenesis. Mbio. 11. PMID 32605987 DOI: 10.1128/Mbio.01296-20  1
2020 Cover TL, Lacy DB, Ohi MD. The Helicobacter pylori Cag Type IV Secretion System. Trends in Microbiology. PMID 32451226 DOI: 10.1016/J.Tim.2020.02.004  1
2020 McClain MS, Voss BJ, Cover TL. Lipoprotein Processing and Sorting in Helicobacter pylori. Mbio. 11. PMID 32430470 DOI: 10.1128/Mbio.00911-20  1
2020 Caston RR, Sierra JC, Foegeding NJ, Truelock MD, Campbell AM, Frick-Cheng AE, Bimczok D, Wilson KT, McClain MS, Cover TL. Functional properties of VacA toxin m1 and m2 variants. Infection and Immunity. PMID 32284370 DOI: 10.1128/Iai.00032-20  1
2019 Noto JM, Rose KL, Hachey AJ, Delgado AG, Romero-Gallo J, Wroblewski LE, Schneider BG, Shah SC, Cover TL, Wilson KT, Israel DA, Roa JC, Schey KL, Zavros Y, Piazuelo MB, et al. Carcinogenic Helicobacter pylori Strains Selectively Dysregulate the In Vivo Gastric Proteome, Which May Be Associated with Stomach Cancer Progression. Molecular & Cellular Proteomics : McP. 18: 352-371. PMID 33451441 DOI: 10.1074/mcp.RA118.001181  1
2019 Lin AS, Dooyema SDR, Frick-Cheng AE, Harvey ML, Suarez G, Loh JT, McDonald WH, McClain MS, Peek RM, Cover TL. Bacterial energetic requirements for Cag Type IV secretion system-dependent alterations in gastric epithelial cells. Infection and Immunity. PMID 31712269 DOI: 10.1128/Iai.00790-19  1
2019 Chung JM, Sheedlo MJ, Campbell AM, Sawhney N, Frick-Cheng AE, Lacy DB, Cover TL, Ohi MD. Structure of the Cag Type IV secretion system. Elife. 8. PMID 31210639 DOI: 10.7554/Elife.47644  1
2019 Hu B, Khara P, Song L, Lin AS, Frick-Cheng AE, Harvey ML, Cover TL, Christie PJ. Molecular Architecture of the Helicobacter pylori Cag Type IV Secretion System. Mbio. 10. PMID 31088930 DOI: 10.1128/Mbio.00849-19  1
2019 Caston RR, Loh JT, Voss BJ, McDonald WH, Scholz MB, McClain MS, Cover TL. Effect of environmental salt concentration on the Helicobacter pylori exoproteome. Journal of Proteomics. PMID 31063819 DOI: 10.1016/J.Jprot.2019.05.002  1
2019 Su M, Erwin AL, Campbell AM, Pyburn TM, Salay LE, Hanks JL, Lacy DB, Akey DL, Cover TL, Ohi MD. Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization. Journal of Molecular Biology. PMID 30954575 DOI: 10.1016/J.Jmb.2019.03.029  1
2019 Altobelli A, Bauer M, Velez K, Cover TL, Müller A. VacA Targets Myeloid Cells in the Gastric Lamina Propria To Promote Peripherally Induced Regulatory T-Cell Differentiation and Persistent Infection. Mbio. 10. PMID 30890606 DOI: 10.1128/Mbio.00261-19  1
2019 Foegeding NJ, Raghunathan K, Campbell AM, Kim SW, Lau KS, Kenworthy AK, Cover TL, Ohi MD. Intracellular degradation of VacA toxin as a determinant of gastric epithelial cell viability. Infection and Immunity. PMID 30692181 DOI: 10.1128/Iai.00783-18  1
2019 Chung JM, Sheedlo MJ, Campbell AM, Sawhney N, Frick-Cheng AE, Lacy DB, Cover TL, Ohi MD. Author response: Structure of the Helicobacter pylori Cag type IV secretion system Elife. DOI: 10.7554/Elife.47644.043  1
2018 Loh JT, Lin AS, Beckett AC, McClain MS, Cover TL. Role of a stem-loop structure in transcript stability. Infection and Immunity. PMID 30510104 DOI: 10.1128/Iai.00692-18  1
2018 Noto JM, Rose K, Hachey AJ, Delgado AG, Romero-Gallo J, Wroblewski LE, Schneider BG, Shah SC, Cover TL, Wilson KT, Israel DA, Roa JC, Schey KL, Zavros Y, Piazuelo MB, et al. Carcinogenic strains selectively dysregulate the gastric proteome, which may be associated with stomach cancer progression. Molecular & Cellular Proteomics : McP. PMID 30455363 DOI: 10.1074/Mcp.Ra118.001181  1
2018 Butt J, Varga MG, Blot WJ, Teras L, Visvanathan K, Le Marchand L, Haiman C, Chen Y, Bao Y, Sesso HD, Wassertheil-Smoller S, Ho GYF, Tinker LE, Peek RM, Potter JD, ... Cover TL, et al. Serological response to Helicobacter pylori proteins associate with risk of colorectal cancer among diverse populations in the United States. Gastroenterology. PMID 30296434 DOI: 10.1053/J.Gastro.2018.09.054  1
2018 Kyburz A, Fallegger A, Zhang X, Altobelli A, Artola-Boran M, Borbet T, Urban S, Paul P, Münz C, Floess S, Huehn J, Cover TL, Blaser MJ, Taube C, Müller A. Trans-maternal Helicobacter pylori exposure reduces allergic airway inflammation in offspring through regulatory T-cells. The Journal of Allergy and Clinical Immunology. PMID 30240703 DOI: 10.1016/J.Jaci.2018.07.046  1
2018 Beckett AC, Loh JT, Chopra A, Leary S, Lin AS, McDonnell WJ, Dixon BREA, Noto JM, Israel DA, Peek RM, Mallal S, Algood HMS, Cover TL. genetic diversification in the Mongolian gerbil model. Peerj. 6: e4803. PMID 29796347 DOI: 10.7717/Peerj.4803  1
2018 Raghunathan K, Foegeding NJ, Campbell AM, Cover TL, Ohi MD, Kenworthy AK. Determinants of raft partitioning of thepore-forming toxin VacA. Infection and Immunity. PMID 29531133 DOI: 10.1128/Iai.00872-17  1
2017 Bullock KK, Shaffer CL, Brooks AW, Secka O, Forsyth MH, McClain MS, Cover TL. Genetic signatures for Helicobacter pylori strains of West African origin. Plos One. 12: e0188804. PMID 29186206 DOI: 10.1371/Journal.Pone.0188804  1
2017 McClain MS, Beckett AC, Cover TL. Helicobacter pylori Vacuolating Toxin and Gastric Cancer. Toxins. 9. PMID 29023421 DOI: 10.3390/Toxins9100316  1
2017 Noto JM, Chopra A, Loh JT, Romero-Gallo J, Piazuelo MB, Watson M, Leary S, Beckett AC, Wilson KT, Cover TL, Mallal S, Israel DA, Peek RM. Pan-genomic analyses identify key Helicobacter pylori pathogenic loci modified by carcinogenic host microenvironments. Gut. PMID 28924022 DOI: 10.1136/Gutjnl-2017-313863  1
2017 Kyburz A, Urban S, Altobelli A, Floess S, Huehn J, Cover TL, Müller A. Helicobacter pylori and its secreted immunomodulator VacA protect against anaphylaxis in experimental models of food allergy. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. PMID 28802077 DOI: 10.1111/Cea.12996  1
2017 Feichtinger RG, Neureiter D, Skaria T, Wessler S, Cover TL, Mayr JA, Zimmermann FA, Posselt G, Sperl W, Kofler B. Oxidative Phosphorylation System in Gastric Carcinomas and Gastritis. Oxidative Medicine and Cellular Longevity. 2017: 1320241. PMID 28744336 DOI: 10.1155/2017/1320241  0.01
2017 Bell CS, Mejias R, Miller S, Greer J, McClain M, Cover TL, Giorgio TD. Magnetic Extraction of Acinetobacter baumannii using Colistin Functionalized γ-Fe2O3/Au Core/Shell Composite Nanoclusters. Acs Applied Materials & Interfaces. PMID 28696672 DOI: 10.1021/Acsami.7B07304  1
2016 Miller SE, Bell CS, Mejias R, McClain MS, Cover TL, Giorgio TD. Colistin-Functionalized Nanoparticles for the Rapid Capture of Acinetobacter baumannii. Journal of Biomedical Nanotechnology. 12: 1806-19. PMID 29345892 DOI: 10.1166/Jbn.2016.2273  1
2016 Miller SE, Bell CS, McClain MS, Cover TL, Giorgio TD. Dynamic Computational Model of Symptomatic Bacteremia to Inform Bacterial Separation Treatment Requirements. Plos One. 11: e0163167. PMID 27657881 DOI: 10.1371/Journal.Pone.0163167  1
2016 Beckett AC, Piazuelo MB, Noto JM, Peek RM, Washington MK, Algood HM, Cover TL. Dietary composition influences incidence of Helicobacter pylori-induced iron deficiency anemia and gastric ulceration. Infection and Immunity. PMID 27620719 DOI: 10.1128/Iai.00479-16  1
2016 Schmitz JE, Taniguchi T, Misawa N, Cover TL. Epithelial Co-Culture and L-Lactate Promote Growth of Helicobacter cinaedi under H2-free Aerobic Conditions. Applied and Environmental Microbiology. PMID 27613684 DOI: 10.1128/Aem.01943-16  0.01
2016 González-Rivera C, Campbell AM, Rutherford SA, Pyburn TM, Foegeding NJ, Barke TL, Spiller BW, McClain MS, Ohi MD, Lacy DB, Cover TL. A non-oligomerizing mutant form of Helicobacter pylori VacA allows structural analysis of the p33 domain. Infection and Immunity. PMID 27382020 DOI: 10.1128/Iai.00254-16  1
2016 Pyburn TM, Foegeding NJ, González-Rivera C, McDonald NA, Gould KL, Cover TL, Ohi MD. Structural organization of membrane-inserted hexamers formed by Helicobacter pylori VacA toxin. Molecular Microbiology. PMID 27309820 DOI: 10.1111/Mmi.13443  1
2016 Foegeding NJ, Caston RR, McClain MS, Ohi MD, Cover TL. An Overview of Helicobacter pylori VacA Toxin Biology. Toxins. 8. PMID 27271669 DOI: 10.3390/Toxins8060173  1
2016 Shaffer CL, Good JA, Kumar S, Krishnan KS, Gaddy JA, Loh JT, Chappell J, Almqvist F, Cover TL, Hadjifrangiskou M. Peptidomimetic Small Molecules Disrupt Type IV Secretion System Activity in Diverse Bacterial Pathogens. Mbio. 7. PMID 27118587 DOI: 10.1128/Mbio.00221-16  1
2016 Cover TL. Helicobacter pylori Diversity and Gastric Cancer Risk. Mbio. 7. PMID 26814181 DOI: 10.1128/Mbio.01869-15  1
2016 Frick-Cheng AE, Pyburn TM, Voss BJ, McDonald WH, Ohi MD, Cover TL. Molecular and Structural Analysis of the Helicobacter pylori cag Type IV Secretion System Core Complex. Mbio. 7. PMID 26758182 DOI: 10.1128/Mbio.02001-15  1
2016 Snider CA, Voss BJ, McDonald WH, Cover TL. Growth phase-dependent composition of the Helicobacter pylori exoproteome. Journal of Proteomics. 130: 94-107. PMID 26363098 DOI: 10.1016/J.Jprot.2015.08.025  1
2016 Miller SE, Bell CS, Mejias R, McClain MS, Cover TL, Giorgio TD. Colistin-functionalized nanoparticles for the rapid capture of acinetobacter baumannii Journal of Biomedical Nanotechnology. 12: 1806-1819. DOI: 10.1166/jbn.2016.2273  1
2015 Snider CA, Voss BJ, McDonald WH, Cover TL. Supporting data for analysis of the Helicobacter pylori exoproteome. Data in Brief. 5: 560-3. PMID 26958609 DOI: 10.1016/J.Dib.2015.10.008  1
2015 Voss BJ, Cover TL. Biotinylation and Purification of Surface-exposed Helicobacter pylori Proteins. Bio-Protocol. 5: e1455. PMID 26448963  1
2015 Loh JT, Gaddy JA, Algood HM, Gaudieri S, Mallal S, Cover TL. Helicobacter pylori Adaptation In Vivo in Response to a High-Salt Diet. Infection and Immunity. 83: 4871-83. PMID 26438795 DOI: 10.1128/Iai.00918-15  1
2015 Voss BJ, Loh JT, Hill S, Rose KL, McDonald WH, Cover TL. Alteration of the Helicobacter pylori membrane proteome in response to changes in environmental salt concentration. Proteomics. Clinical Applications. PMID 26109032 DOI: 10.1002/Prca.201400176  1
2015 Noto JM, Lee JY, Gaddy JA, Cover TL, Amieva MR, Peek RM. Regulation of Helicobacter pylori Virulence Within the Context of Iron Deficiency. The Journal of Infectious Diseases. 211: 1790-4. PMID 25505301 DOI: 10.1093/Infdis/Jiu805  1
2014 Gaddy JA, Radin JN, Loh JT, Piazuelo MB, Kehl-Fie TE, Delgado AG, Ilca FT, Peek RM, Cover TL, Chazin WJ, Skaar EP, Scott Algood HM. The host protein calprotectin modulates the Helicobacter pylori cag type IV secretion system via zinc sequestration. Plos Pathogens. 10: e1004450. PMID 25330071 DOI: 10.1371/Journal.Ppat.1004450  1
2014 Engler DB, Reuter S, van Wijck Y, Urban S, Kyburz A, Maxeiner J, Martin H, Yogev N, Waisman A, Gerhard M, Cover TL, Taube C, Müller A. Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10. Proceedings of the National Academy of Sciences of the United States of America. 111: 11810-5. PMID 25074917 DOI: 10.1073/Pnas.1410579111  1
2014 Voss BJ, Gaddy JA, McDonald WH, Cover TL. Analysis of surface-exposed outer membrane proteins in Helicobacter pylori. Journal of Bacteriology. 196: 2455-71. PMID 24769695 DOI: 10.1128/Jb.01768-14  1
2014 Kodaman N, Pazos A, Schneider BG, Piazuelo MB, Mera R, Sobota RS, Sicinschi LA, Shaffer CL, Romero-Gallo J, de Sablet T, Harder RH, Bravo LE, Peek RM, Wilson KT, Cover TL, et al. Human and Helicobacter pylori coevolution shapes the risk of gastric disease. Proceedings of the National Academy of Sciences of the United States of America. 111: 1455-60. PMID 24474772 DOI: 10.1073/Pnas.1318093111  1
2014 Radin JN, González-Rivera C, Frick-Cheng AE, Sheng J, Gaddy JA, Rubin DH, Algood HM, McClain MS, Cover TL. Role of connexin 43 in Helicobacter pylori VacA-induced cell death. Infection and Immunity. 82: 423-32. PMID 24191302 DOI: 10.1128/Iai.00827-13  1
2014 Cover TL, Blaser MJ. Helicobacter pylori and Other Gastric Helicobacter Species Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 2: 2494-2502.e4. DOI: 10.1016/B978-1-4557-4801-3.00219-8  1
2013 McClain MS, Duncan SS, Gaddy JA, Cover TL. Control of gene expression in Helicobacter pylori using the Tet repressor. Journal of Microbiological Methods. 95: 336-41. PMID 24113399 DOI: 10.1016/J.Mimet.2013.09.019  1
2013 Duncan SS, Bertoli MT, Kersulyte D, Valk PL, Tamma S, Segal I, McClain MS, Cover TL, Berg DE. Genome Sequences of Three hpAfrica2 Strains of Helicobacter pylori. Genome Announcements. 1. PMID 24072860 DOI: 10.1128/Genomea.00729-13  1
2013 Cover TL, Peek RM. Diet, microbial virulence, and Helicobacter pylori-induced gastric cancer. Gut Microbes. 4: 482-93. PMID 23989802 DOI: 10.4161/Gmic.26262  1
2013 Parekh VV, Wu L, Boyd KL, Williams JA, Gaddy JA, Olivares-Villagómez D, Cover TL, Zong WX, Zhang J, Van Kaer L. Impaired autophagy, defective T cell homeostasis, and a wasting syndrome in mice with a T cell-specific deletion of Vps34. Journal of Immunology (Baltimore, Md. : 1950). 190: 5086-101. PMID 23596309 DOI: 10.4049/Jimmunol.1202071  1
2013 Radin JN, Gaddy JA, González-Rivera C, Loh JT, Algood HM, Cover TL. Flagellar localization of a Helicobacter pylori autotransporter protein. Mbio. 4: e00613-12. PMID 23572556 DOI: 10.1128/Mbio.00613-12  1
2013 Gaddy JA, Radin JN, Loh JT, Zhang F, Washington MK, Peek RM, Algood HM, Cover TL. High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis. Infection and Immunity. 81: 2258-67. PMID 23569116 DOI: 10.1128/Iai.01271-12  1
2013 Barrozo RM, Cooke CL, Hansen LM, Lam AM, Gaddy JA, Johnson EM, Cariaga TA, Suarez G, Peek RM, Cover TL, Solnick JV. Functional plasticity in the type IV secretion system of Helicobacter pylori. Plos Pathogens. 9: e1003189. PMID 23468628 DOI: 10.1371/Journal.Ppat.1003189  1
2013 Duncan SS, Valk PL, McClain MS, Shaffer CL, Metcalf JA, Bordenstein SR, Cover TL. Comparative genomic analysis of East Asian and non-Asian Helicobacter pylori strains identifies rapidly evolving genes. Plos One. 8: e55120. PMID 23383074 DOI: 10.1371/Journal.Pone.0055120  1
2013 Serrano C, Wright SW, Bimczok D, Shaffer CL, Cover TL, Venegas A, Salazar MG, Smythies LE, Harris PR, Smith PD. Downregulated Th17 responses are associated with reduced gastritis in Helicobacter pylori-infected children. Mucosal Immunology. 6: 950-9. PMID 23299619 DOI: 10.1038/Mi.2012.133  1
2013 Noto JM, Gaddy JA, Lee JY, Piazuelo MB, Friedman DB, Colvin DC, Romero-Gallo J, Suarez G, Loh J, Slaughter JC, Tan S, Morgan DR, Wilson KT, Bravo LE, Correa P, ... Cover TL, et al. Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans. The Journal of Clinical Investigation. 123: 479-92. PMID 23257361 DOI: 10.1172/Jci64373  1
2013 Chambers MG, Pyburn TM, González-Rivera C, Collier SE, Eli I, Yip CK, Takizawa Y, Lacy DB, Cover TL, Ohi MD. Structural analysis of the oligomeric states of Helicobacter pylori VacA toxin. Journal of Molecular Biology. 425: 524-35. PMID 23178866 DOI: 10.1016/J.Jmb.2012.11.020  1
2012 Cover TL. Perspectives on methodology for in vitro culture of Helicobacter pylori. Methods in Molecular Biology (Clifton, N.J.). 921: 11-5. PMID 23015486 DOI: 10.1007/978-1-62703-005-2_3  1
2012 Conradi J, Tegtmeyer N, Woźna M, Wissbrock M, Michalek C, Gagell C, Cover TL, Frank R, Sewald N, Backert S. An RGD helper sequence in CagL of Helicobacter pylori assists in interactions with integrins and injection of CagA. Frontiers in Cellular and Infection Microbiology. 2: 70. PMID 22919661 DOI: 10.3389/Fcimb.2012.00070  1
2012 Johnson EM, Gaddy JA, Cover TL. Alterations in Helicobacter pylori triggered by contact with gastric epithelial cells. Frontiers in Cellular and Infection Microbiology. 2: 17. PMID 22919609 DOI: 10.3389/Fcimb.2012.00017  1
2012 Loh JT, Friedman DB, Piazuelo MB, Bravo LE, Wilson KT, Peek RM, Correa P, Cover TL. Analysis of Helicobacter pylori cagA promoter elements required for salt-induced upregulation of CagA expression. Infection and Immunity. 80: 3094-106. PMID 22710874 DOI: 10.1128/Iai.00232-12  0.52
2012 González-Rivera C, Algood HM, Radin JN, McClain MS, Cover TL. The intermediate region of Helicobacter pylori VacA is a determinant of toxin potency in a Jurkat T cell assay. Infection and Immunity. 80: 2578-88. PMID 22585965 DOI: 10.1128/Iai.00052-12  1
2012 Cover TL. Role of Helicobacter pylori CagL in modulating gastrin expression. Gut. 61: 965-6. PMID 22406936 DOI: 10.1136/Gutjnl-2012-302142  1
2012 Sicinschi LA, Correa P, Bravo LE, Peek RM, Wilson KT, Loh JT, Yepez MC, Gold BD, Thompson DT, Cover TL, Schneider BG. Non-invasive genotyping of Helicobacter pylori cagA, vacA, and hopQ from asymptomatic children. Helicobacter. 17: 96-106. PMID 22404439 DOI: 10.1111/J.1523-5378.2011.00919.X  1
2012 Duncan SS, Valk PL, Shaffer CL, Bordenstein SR, Cover TL. J-Western forms of Helicobacter pylori cagA constitute a distinct phylogenetic group with a widespread geographic distribution. Journal of Bacteriology. 194: 1593-604. PMID 22247512 DOI: 10.1128/Jb.06340-11  1
2011 Shaffer CL, Gaddy JA, Loh JT, Johnson EM, Hill S, Hennig EE, McClain MS, McDonald WH, Cover TL. Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface. Plos Pathogens. 7: e1002237. PMID 21909278 DOI: 10.1371/Journal.Ppat.1002237  1
2011 Loh JT, Shaffer CL, Piazuelo MB, Bravo LE, McClain MS, Correa P, Cover TL. Analysis of cagA in Helicobacter pylori strains from Colombian populations with contrasting gastric cancer risk reveals a biomarker for disease severity. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 20: 2237-49. PMID 21859954 DOI: 10.1158/1055-9965.Epi-11-0548  1
2011 Nagy TA, Wroblewski LE, Wang D, Piazuelo MB, Delgado A, Romero-Gallo J, Noto J, Israel DA, Ogden SR, Correa P, Cover TL, Peek RM. β-Catenin and p120 mediate PPARδ-dependent proliferation induced by Helicobacter pylori in human and rodent epithelia. Gastroenterology. 141: 553-64. PMID 21704622 DOI: 10.1053/J.Gastro.2011.05.004  1
2011 Yan F, Cao H, Cover TL, Washington MK, Shi Y, Liu L, Chaturvedi R, Peek RM, Wilson KT, Polk DB. Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism. The Journal of Clinical Investigation. 121: 2242-53. PMID 21606592 DOI: 10.1172/Jci44031  1
2011 Radin JN, González-Rivera C, Ivie SE, McClain MS, Cover TL. Helicobacter pylori VacA induces programmed necrosis in gastric epithelial cells. Infection and Immunity. 79: 2535-43. PMID 21482684 DOI: 10.1128/Iai.01370-10  1
2011 de Sablet T, Piazuelo MB, Shaffer CL, Schneider BG, Asim M, Chaturvedi R, Bravo LE, Sicinschi LA, Delgado AG, Mera RM, Israel DA, Romero-Gallo J, Peek RM, Cover TL, Correa P, et al. Phylogeographic origin of Helicobacter pylori is a determinant of gastric cancer risk. Gut. 60: 1189-95. PMID 21357593 DOI: 10.1136/Gut.2010.234468  1
2010 Gangwer KA, Shaffer CL, Suerbaum S, Lacy DB, Cover TL, Bordenstein SR. Molecular evolution of the Helicobacter pylori vacuolating toxin gene vacA. Journal of Bacteriology. 192: 6126-35. PMID 20870762 DOI: 10.1128/Jb.01081-10  1
2010 Shen F, Hobley L, Doherty N, Loh JT, Cover TL, Sockett RE, Hardie KR, Atherton JC. In Helicobacter pylori auto-inducer-2, but not LuxS/MccAB catalysed reverse transsulphuration, regulates motility through modulation of flagellar gene transcription. Bmc Microbiology. 10: 210. PMID 20691071 DOI: 10.1186/1471-2180-10-210  1
2010 González-Rivera C, Gangwer KA, McClain MS, Eli IM, Chambers MG, Ohi MD, Lacy DB, Cover TL. Reconstitution of Helicobacter pylori VacA toxin from purified components. Biochemistry. 49: 5743-52. PMID 20527875 DOI: 10.1021/Bi100618G  1
2010 Ivie SE, McClain MS, Algood HM, Lacy DB, Cover TL. Analysis of a beta-helical region in the p55 domain of Helicobacter pylori vacuolating toxin. Bmc Microbiology. 10: 60. PMID 20178613 DOI: 10.1186/1471-2180-10-60  1
2010 Loh JT, Gupta SS, Friedman DB, Krezel AM, Cover TL. Analysis of protein expression regulated by the Helicobacter pylori ArsRS two-component signal transduction system. Journal of Bacteriology. 192: 2034-43. PMID 20154125 DOI: 10.1128/Jb.01703-08  1
2009 Algood HM, Allen SS, Washington MK, Peek RM, Miller GG, Cover TL. Regulation of gastric B cell recruitment is dependent on IL-17 receptor A signaling in a model of chronic bacterial infection. Journal of Immunology (Baltimore, Md. : 1950). 183: 5837-46. PMID 19812196 DOI: 10.4049/Jimmunol.0901206  1
2009 Cover TL, Blaser MJ. Helicobacter pylori in health and disease. Gastroenterology. 136: 1863-73. PMID 19457415 DOI: 10.1053/J.Gastro.2009.01.073  1
2009 Yan F, Cao H, Chaturvedi R, Krishna U, Hobbs SS, Dempsey PJ, Peek RM, Cover TL, Washington MK, Wilson KT, Polk DB. Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis. Gastroenterology. 136: 1297-1307, e1-3. PMID 19250983 DOI: 10.1053/J.Gastro.2008.12.059  1
2009 McClain MS, Shaffer CL, Israel DA, Peek RM, Cover TL. Genome sequence analysis of Helicobacter pylori strains associated with gastric ulceration and gastric cancer. Bmc Genomics. 10: 3. PMID 19123947 DOI: 10.1186/1471-2164-10-3  1
2009 Gupta SS, Borin BN, Cover TL, Krezel AM. Structural analysis of the DNA-binding domain of the Helicobacter pylori response regulator ArsR. The Journal of Biological Chemistry. 284: 6536-45. PMID 19117956 DOI: 10.1074/Jbc.M804592200  1
2008 Loh JT, Torres VJ, Algood HM, McClain MS, Cover TL. Helicobacter pylori HopQ outer membrane protein attenuates bacterial adherence to gastric epithelial cells. Fems Microbiology Letters. 289: 53-8. PMID 19065710 DOI: 10.1111/J.1574-6968.2008.01368.X  1
2008 Wang F, Xia P, Wu F, Wang D, Wang W, Ward T, Liu Y, Aikhionbare F, Guo Z, Powell M, Liu B, Bi F, Shaw A, Zhu Z, Elmoselhi A, ... ... Cover TL, et al. Helicobacter pylori VacA disrupts apical membrane-cytoskeletal interactions in gastric parietal cells. The Journal of Biological Chemistry. 283: 26714-25. PMID 18625712 DOI: 10.1074/Jbc.M800527200  1
2008 Ding SZ, Olekhnovich IN, Cover TL, Peek RM, Smith MF, Goldberg JB. Helicobacter pylori and mitogen-activated protein kinases mediate activator protein-1 (AP-1) subcomponent protein expression and DNA-binding activity in gastric epithelial cells. Fems Immunology and Medical Microbiology. 53: 385-94. PMID 18625013 DOI: 10.1111/J.1574-695X.2008.00439.X  1
2008 Ivie SE, McClain MS, Torres VJ, Algood HM, Lacy DB, Yang R, Blanke SR, Cover TL. Helicobacter pylori VacA subdomain required for intracellular toxin activity and assembly of functional oligomeric complexes. Infection and Immunity. 76: 2843-51. PMID 18443094 DOI: 10.1128/Iai.01664-07  1
2008 Cover TL. Beta2 integrin mediates entry of a bacterial toxin into T lymphocytes. Cell Host & Microbe. 3: 5-6. PMID 18191787 DOI: 10.1016/J.Chom.2007.12.004  1
2007 Algood HM, Gallo-Romero J, Wilson KT, Peek RM, Cover TL. Host response to Helicobacter pylori infection before initiation of the adaptive immune response. Fems Immunology and Medical Microbiology. 51: 577-86. PMID 17919297 DOI: 10.1111/J.1574-695X.2007.00338.X  1
2007 Torres VJ, VanCompernolle SE, Sundrud MS, Unutmaz D, Cover TL. Helicobacter pylori vacuolating cytotoxin inhibits activation-induced proliferation of human T and B lymphocyte subsets. Journal of Immunology (Baltimore, Md. : 1950). 179: 5433-40. PMID 17911630 DOI: 10.4049/Jimmunol.179.8.5433  1
2007 Gangwer KA, Mushrush DJ, Stauff DL, Spiller B, McClain MS, Cover TL, Lacy DB. Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain. Proceedings of the National Academy of Sciences of the United States of America. 104: 16293-8. PMID 17911250 DOI: 10.1073/Pnas.0707447104  1
2007 Chaturvedi R, Asim M, Lewis ND, Algood HM, Cover TL, Kim PY, Wilson KT. L-arginine availability regulates inducible nitric oxide synthase-dependent host defense against Helicobacter pylori. Infection and Immunity. 75: 4305-15. PMID 17562760 DOI: 10.1128/Iai.00578-07  1
2007 Loh JT, Torres VJ, Cover TL. Regulation of Helicobacter pylori cagA expression in response to salt. Cancer Research. 67: 4709-15. PMID 17510398 DOI: 10.1158/0008-5472.Can-06-4746  1
2007 Ghose C, Perez-Perez GI, Torres VJ, Crosatti M, Nomura A, Peek RM, Cover TL, Francois F, Blaser MJ. Serological assays for identification of human gastric colonization by Helicobacter pylori strains expressing VacA m1 or m2. Clinical and Vaccine Immunology : Cvi. 14: 442-50. PMID 17267587 DOI: 10.1128/Cvi.00434-06  1
2007 McClain MS, Cover TL. Functional analysis of neutralizing antibodies against Clostridium perfringens epsilon-toxin. Infection and Immunity. 75: 1785-93. PMID 17261609 DOI: 10.1128/Iai.01643-06  1
2007 Yan F, Cao H, Cover TL, Whitehead R, Washington MK, Polk DB. Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology. 132: 562-75. PMID 17258729 DOI: 10.1053/J.Gastro.2006.11.022  1
2007 Algood HM, Torres VJ, Unutmaz D, Cover TL. Resistance of primary murine CD4+ T cells to Helicobacter pylori vacuolating cytotoxin. Infection and Immunity. 75: 334-41. PMID 17074854 DOI: 10.1128/Iai.01063-06  1
2006 Cover TL. Role of Helicobacter pylori outer membrane proteins in gastroduodenal disease. The Journal of Infectious Diseases. 194: 1343-5. PMID 17054062 DOI: 10.1086/508432  1
2006 Algood HM, Cover TL. Helicobacter pylori persistence: an overview of interactions between H. pylori and host immune defenses. Clinical Microbiology Reviews. 19: 597-613. PMID 17041136 DOI: 10.1128/Cmr.00006-06  1
2006 Oswald-Richter K, Torres VJ, Sundrud MS, VanCompernolle SE, Cover TL, Unutmaz D. Helicobacter pylori VacA toxin inhibits human immunodeficiency virus infection of primary human T cells. Journal of Virology. 80: 11767-75. PMID 17005643 DOI: 10.1128/Jvi.00213-06  1
2006 McClain MS, Czajkowsky DM, Torres VJ, Szabo G, Shao Z, Cover TL. Random mutagenesis of Helicobacter pylori vacA to identify amino acids essential for vacuolating cytotoxic activity. Infection and Immunity. 74: 6188-95. PMID 16954403 DOI: 10.1128/Iai.00915-06  1
2006 Lee WK, Ogura K, Loh JT, Cover TL, Berg DE. Quantitative effect of luxS gene inactivation on the fitness of Helicobacter pylori. Applied and Environmental Microbiology. 72: 6615-22. PMID 16936059 DOI: 10.1128/Aem.01291-06  1
2006 Busler VJ, Torres VJ, McClain MS, Tirado O, Friedman DB, Cover TL. Protein-protein interactions among Helicobacter pylori cag proteins. Journal of Bacteriology. 188: 4787-800. PMID 16788188 DOI: 10.1128/Jb.00066-06  1
2006 Loh JT, Cover TL. Requirement of histidine kinases HP0165 and HP1364 for acid resistance in Helicobacter pylori. Infection and Immunity. 74: 3052-9. PMID 16622250 DOI: 10.1128/Iai.74.5.3052-3059.2006  1
2006 Hennig EE, Allen JM, Cover TL. Multiple chromosomal loci for the babA gene in Helicobacter pylori. Infection and Immunity. 74: 3046-51. PMID 16622249 DOI: 10.1128/Iai.74.5.3046-3051.2006  1
2006 Torres VJ, McClain MS, Cover TL. Mapping of a domain required for protein-protein interactions and inhibitory activity of a Helicobacter pylori dominant-negative VacA mutant protein. Infection and Immunity. 74: 2093-101. PMID 16552038 DOI: 10.1128/Iai.74.4.2093-2101.2006  1
2006 McClain MS, Cover TL. Helicobacter pylori vacuolating toxin The Comprehensive Sourcebook of Bacterial Protein Toxins. 468-490. DOI: 10.1016/B978-012088445-2/50029-9  1
2005 Johansson M, Lehto M, Tanhuanpää K, Cover TL, Olkkonen VM. The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments. Molecular Biology of the Cell. 16: 5480-92. PMID 16176980 DOI: 10.1091/Mbc.E05-03-0189  1
2005 El-Bez C, Adrian M, Dubochet J, Cover TL. High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy. Journal of Structural Biology. 151: 215-28. PMID 16125415 DOI: 10.1016/J.Jsb.2005.07.001  1
2005 Cao P, Lee KJ, Blaser MJ, Cover TL. Analysis of hopQ alleles in East Asian and Western strains of Helicobacter pylori. Fems Microbiology Letters. 251: 37-43. PMID 16102915 DOI: 10.1016/J.Femsle.2005.07.023  1
2005 Czajkowsky DM, Iwamoto H, Szabo G, Cover TL, Shao Z. Mimicry of a host anion channel by a Helicobacter pylori pore-forming toxin. Biophysical Journal. 89: 3093-101. PMID 16100263 DOI: 10.1529/Biophysj.105.066746  1
2005 Terry CE, McGinnis LM, Madigan KC, Cao P, Cover TL, Liechti GW, Peek RM, Forsyth MH. Genomic Comparison of cag pathogenicity island (PAI)-positive and -negative Helicobacter pylori strains: identification of novel markers for cag PAI-positive strains. Infection and Immunity. 73: 3794-8. PMID 15908415 DOI: 10.1128/Iai.73.6.3794-3798.2005  1
2005 Torres VJ, Ivie SE, McClain MS, Cover TL. Functional properties of the p33 and p55 domains of the Helicobacter pylori vacuolating cytotoxin. The Journal of Biological Chemistry. 280: 21107-14. PMID 15817461 DOI: 10.1074/Jbc.M501042200  1
2005 Cover TL, Blanke SR. Helicobacter pylori VacA, a paradigm for toxin multifunctionality. Nature Reviews. Microbiology. 3: 320-32. PMID 15759043 DOI: 10.1038/Nrmicro1095  1
2004 Loh JT, Forsyth MH, Cover TL. Growth phase regulation of flaA expression in Helicobacter pylori is luxS dependent. Infection and Immunity. 72: 5506-10. PMID 15322055 DOI: 10.1128/Iai.72.9.5506-5510.2004  1
2004 Hennig EE, Mernaugh R, Edl J, Cao P, Cover TL. Heterogeneity among Helicobacter pylori strains in expression of the outer membrane protein BabA. Infection and Immunity. 72: 3429-35. PMID 15155649 DOI: 10.1128/Iai.72.6.3429-3435.2004  1
2004 Sundrud MS, Torres VJ, Unutmaz D, Cover TL. Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion. Proceedings of the National Academy of Sciences of the United States of America. 101: 7727-32. PMID 15128946 DOI: 10.1073/Pnas.0401528101  1
2004 Geisse NA, Cover TL, Henderson RM, Edwardson JM. Targeting of Helicobacter pylori vacuolating toxin to lipid raft membrane domains analysed by atomic force microscopy. The Biochemical Journal. 381: 911-7. PMID 15128269 DOI: 10.1042/Bj20031719  1
2004 Li Y, Wandinger-Ness A, Goldenring JR, Cover TL. Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin. Molecular Biology of the Cell. 15: 1946-59. PMID 14742715 DOI: 10.1091/Mbc.E03-08-0618  1
2004 Torres VJ, McClain MS, Cover TL. Interactions between p-33 and p-55 domains of the Helicobacter pylori vacuolating cytotoxin (VacA). The Journal of Biological Chemistry. 279: 2324-31. PMID 14593124 DOI: 10.1074/Jbc.M310159200  1
2003 Willhite DC, Cover TL, Blanke SR. Cellular vacuolation and mitochondrial cytochrome c release are independent outcomes of Helicobacter pylori vacuolating cytotoxin activity that are each dependent on membrane channel formation. The Journal of Biological Chemistry. 278: 48204-9. PMID 13129933 DOI: 10.1074/Jbc.M304131200  1
2003 Fonteneau JF, Kavanagh DG, Lirvall M, Sanders C, Cover TL, Bhardwaj N, Larsson M. Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells. Blood. 102: 4448-55. PMID 12933572 DOI: 10.1182/Blood-2003-06-1801  1
2003 McGowan CC, Necheva AS, Forsyth MH, Cover TL, Blaser MJ. Promoter analysis of Helicobacter pylori genes with enhanced expression at low pH. Molecular Microbiology. 48: 1225-39. PMID 12787351 DOI: 10.1046/J.1365-2958.2003.03500.X  1
2003 McClain MS, Cover TL. Expression of Helicobacter pylori vacuolating toxin in Escherichia coli. Infection and Immunity. 71: 2266-71. PMID 12654854 DOI: 10.1128/Iai.71.4.2266-2271.2003  1
2003 Cover TL, Krishna US, Israel DA, Peek RM. Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin. Cancer Research. 63: 951-7. PMID 12615708  1
2003 Marlink KL, Bacon KD, Sheppard BC, Ashktorab H, Smoot DT, Cover TL, Deveney CW, Rutten MJ. Effects of Helicobacter pylori on intracellular Ca2+ signaling in normal human gastric mucous epithelial cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G163-76. PMID 12606301 DOI: 10.1152/Ajpgi.00257.2002  1
2003 McClain MS, Iwamoto H, Cao P, Vinion-Dubiel AD, Li Y, Szabo G, Shao Z, Cover TL. Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin. The Journal of Biological Chemistry. 278: 12101-8. PMID 12562777 DOI: 10.1074/Jbc.M212595200  1
2003 Nabekura T, Morishima S, Cover TL, Mori S, Kannan H, Komune S, Okada Y. Recovery from lactacidosis-induced glial cell swelling with the aid of exogenous anion channels. Glia. 41: 247-59. PMID 12528180 DOI: 10.1002/Glia.10190  1
2002 Cao P, Cover TL. Two different families of hopQ alleles in Helicobacter pylori. Journal of Clinical Microbiology. 40: 4504-11. PMID 12454143 DOI: 10.1128/Jcm.40.12.4504-4511.2002  1
2002 Drake WP, Pei Z, Pride DT, Collins RD, Cover TL, Blaser MJ. Molecular analysis of sarcoidosis tissues for mycobacterium species DNA. Emerging Infectious Diseases. 8: 1334-41. PMID 12453366 DOI: 10.3201/Eid0811.020318  1
2002 Graham JE, Peek RM, Krishna U, Cover TL. Global analysis of Helicobacter pylori gene expression in human gastric mucosa. Gastroenterology. 123: 1637-48. PMID 12404238 DOI: 10.1053/Gast.2002.36589  1
2002 Ikonomov OC, Sbrissa D, Yoshimori T, Cover TL, Shisheva A. PIKfyve Kinase and SKD1 AAA ATPase define distinct endocytic compartments. Only PIKfyve expression inhibits the cell-vacoulating activity of Helicobacter pylori VacA toxin. The Journal of Biological Chemistry. 277: 46785-90. PMID 12213828 DOI: 10.1074/Jbc.M208068200  1
2002 Forsyth MH, Cao P, Garcia PP, Hall JD, Cover TL. Genome-wide transcriptional profiling in a histidine kinase mutant of Helicobacter pylori identifies members of a regulon. Journal of Bacteriology. 184: 4630-5. PMID 12142435 DOI: 10.1128/Jb.184.16.4630-4635.2002  1
2002 Schraw W, Li Y, McClain MS, van der Goot FG, Cover TL. Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts. The Journal of Biological Chemistry. 277: 34642-50. PMID 12121984 DOI: 10.1074/Jbc.M203466200  1
2002 Adrian M, Cover TL, Dubochet J, Heuser JE. Multiple oligomeric states of the Helicobacter pylori vacuolating toxin demonstrated by cryo-electron microscopy. Journal of Molecular Biology. 318: 121-33. PMID 12054773 DOI: 10.1016/S0022-2836(02)00047-5  1
2001 McClain MS, Cao P, Iwamoto H, Vinion-Dubiel AD, Szabo G, Shao Z, Cover TL. A 12-amino-acid segment, present in type s2 but not type s1 Helicobacter pylori VacA proteins, abolishes cytotoxin activity and alters membrane channel formation. Journal of Bacteriology. 183: 6499-508. PMID 11673417 DOI: 10.1128/Jb.183.22.6499-6508.2001  1
2001 Papini E, Zoratti M, Cover TL. In search of the Helicobacter pylori VacA mechanism of action Toxicon. 39: 1757-1767. PMID 11595638 DOI: 10.1016/S0041-0101(01)00162-3  1
2001 Vinion-Dubiel AD, McClain MS, Cao P, Mernaugh RL, Cover TL. Antigenic diversity among Helicobacter pylori vacuolating toxins. Infection and Immunity. 69: 4329-36. PMID 11401970 DOI: 10.1128/Iai.69.7.4329-4336.2001  1
2001 Tham KT, Peek RM, Atherton JC, Cover TL, Perez-Perez GI, Shyr Y, Blaser MJ. Helicobacter pylori genotypes, host factors, and gastric mucosal histopathology in peptic ulcer disease Human Pathology. 32: 264-273. PMID 11274634 DOI: 10.1053/Hupa.2001.21136  1
2001 McClain MS, Cao P, Cover TL. Amino-terminal hydrophobic region of Helicobacter pylori vacuolating cytotoxin (VacA) mediates transmembrane protein dimerization. Infection and Immunity. 69: 1181-4. PMID 11160018 DOI: 10.1128/Iai.69.2.1181-1184.2001  1
2001 Nguyen VQ, Caprioli RM, Cover TL. Carboxy-terminal proteolytic processing of Helicobacter pylori vacuolating toxin. Infection and Immunity. 69: 543-6. PMID 11119549 DOI: 10.1128/Iai.69.1.543-546.2001  1
2000 McClain MS, Schraw W, Ricci V, Boquet P, Cover TL. Acid activation of Helicobacter pylori vacuolating cytotoxin (VacA) results in toxin internalization by eukaryotic cells Molecular Microbiology. 37: 433-442. PMID 10931337 DOI: 10.1046/J.1365-2958.2000.02013.X  1
2000 Forsyth MH, Cover TL. Intercellular communication in Helicobacter pylori: luxS is essential for the production of an extracellular signaling molecule Infection and Immunity. 68: 3193-3199. PMID 10816463 DOI: 10.1128/Iai.68.6.3193-3199.2000  1
2000 Hotchin NA, Cover TL, Akhtar N. Cell vacuolation induced by the VacA cytotoxin of Helicobacter pylori is regulated by the Rac1 GTPase Journal of Biological Chemistry. 275: 14009-14012. PMID 10747859 DOI: 10.1074/Jbc.C000153200  1
1999 Peek RM, Blaser MJ, Mays DJ, Forsyth MH, Cover TL, Song SY, Krishna U, Pietenpol JA. Helicobacter pylori strain-specific genotypes and modulation of the gastric epithelial cell cycle Cancer Research. 59: 6124-6131. PMID 10626802  1
1999 Vinion-Dubiel AD, McClain MS, Czajkowsky DM, Iwamoto H, Ye D, Cao P, Schraw W, Szabo G, Blanke SR, Shao Z, Cover TL. A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation. The Journal of Biological Chemistry. 274: 37736-42. PMID 10608833 DOI: 10.1074/Jbc.274.53.37736  1
1999 Schraw W, McClain MS, Cover TL. Kinetics and mechanisms of extracellular protein release by Helicobacter pylori Infection and Immunity. 67: 5247-5252. PMID 10496902 DOI: 10.1128/Iai.67.10.5247-5252.1999  1
1999 Atherton JC, Sharp PM, Cover TL, Gonzalez-Valencia G, Peek RM, Thompson SA, Hawkey CJ, Blaser MJ. Vacuolating cytotoxin (vacA) alleles of Helicobacter pylori comprise two geographically widespread types, m1 and m2, and have evolved through limited recombination Current Microbiology. 39: 211-218. PMID 10486057 DOI: 10.1007/S002849900447  1
1999 Atherton JC, Cover TL, Twells RJ, Morales MR, Hawkey CJ, Blaser MJ. Simple and accurate PCR-based system for typing vacuolating cytotoxin alleles of Helicobacter pylori Journal of Clinical Microbiology. 37: 2979-2982. PMID 10449485 DOI: 10.1128/Jcm.37.9.2979-2982.1999  1
1999 Pai R, Cover TL, Tarnawski AS. Helicobacter pylori vacuolating cytotoxin (VacA) disorganizes the cytoskeletal architecture of gastric epithelial cells Biochemical and Biophysical Research Communications. 262: 245-250. PMID 10448099 DOI: 10.1006/Bbrc.1999.1194  1
1999 Fiocca R, Necchi V, Sommi P, Ricci V, Telford J, Cover TL, Solcia E. Release of Helicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and vesicles by gastric epithelium Journal of Pathology. 188: 220-226. PMID 10398168 DOI: 10.1002/(Sici)1096-9896(199906)188:2<220::Aid-Path307>3.0.Co;2-C  1
1999 Perez-Perez GI, Peek RM, Atherton JC, Blaser MJ, Cover TL. Detection of anti-vacA antibody responses in serum and gastric juice samples using type s1/m1 and s2/m2 Helicobacter pylori vacA antigens Clinical and Diagnostic Laboratory Immunology. 6: 489-493. PMID 10391848 DOI: 10.1128/Cdli.6.4.489-493.1999  1
1999 Cover TL, Blaser MJ. Helicobacter pylori factors associated with disease Gastroenterology. 117: 257-260. PMID 10381935 DOI: 10.1016/S0016-5085(99)70575-5  1
1999 Iwamoto H, Czajkowsky DM, Cover TL, Szabo G, Shao Z. VacA from Helicobacter pylori: A hexameric chloride channel Febs Letters. 450: 101-104. PMID 10350065 DOI: 10.1016/S0014-5793(99)00474-3  1
1999 Forsyth MH, Cover TL. Mutational analysis of the vacA promoter provides insight into gene transcription in Helicobacter priori Journal of Bacteriology. 181: 2261-2266. PMID 10094707 DOI: 10.1128/Jb.181.7.2261-2266.1999  1
1999 Czajkowsky DM, Iwamoto H, Cover TL, Shao Z. The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH Proceedings of the National Academy of Sciences of the United States of America. 96: 2001-2006. PMID 10051584 DOI: 10.1073/Pnas.96.5.2001  1
1998 McGowan CC, Necheva A, Thompson SA, Cover TL, Blaser MJ. Acid-induced expression of an LPS-associated gene in Helicobacter pylori. Molecular Microbiology. 30: 19-31. PMID 9786182 DOI: 10.1046/J.1365-2958.1998.T01-1-01079.X  1
1998 Pagliaccia C, De Bernard M, Lupetti P, Ji X, Burroni D, Cover TL, Papini E, Rappuoli R, Telford JL, Reyrat JM. The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity Proceedings of the National Academy of Sciences of the United States of America. 95: 10212-10217. PMID 9707626 DOI: 10.1073/Pnas.95.17.10212  1
1998 Lehmann FS, Schiller N, Cover T, Hatch R, Seensalu R, Kato K, Walsh JH, Soll AH. H. pylori stimulates gastrin release from canine antral cells in primary culture. The American Journal of Physiology. 274: G992-6. PMID 9696722 DOI: 10.1152/Ajpgi.1998.274.6.G992  1
1998 Forsyth MH, Atherton JC, Blaser MJ, Cover TL. Heterogeneity in levels of vacuolating cytotoxin gene (vacA) transcription among Helicobacter pylori strains Infection and Immunity. 66: 3088-3094. PMID 9632570 DOI: 10.1128/Iai.66.7.3088-3094.1998  1
1998 Pai R, Wyle FA, Cover TL, Itani RM, Domek MJ, Tarnawski AS. Helicobacter pylori culture supernatant interferes with epidermal growth factor-activated signal transduction in human gastric KATO III cells American Journal of Pathology. 152: 1617-1624. PMID 9626065  1
1998 Cao P, McClain MS, Forsyth MH, Cover TL. Extracellular release of antigenic proteins by Helicobacter pylori Infection and Immunity. 66: 2984-2986. PMID 9596777 DOI: 10.1128/Iai.66.6.2984-2986.1998  1
1998 Cover TL. An intracellular target for Helicobacter pylori vacuolating toxin Trends in Microbiology. 6: 127-128; discussion . PMID 9587185 DOI: 10.1016/S0966-842X(98)01231-1  1
1998 Romano M, Ricci V, Di Popolo A, Sommi P, Del Vecchio Blanco C, Bruni CB, Ventura U, Cover TL, Blaser MJ, Coffey RJ, Zarrilli R. Helicobacter pylori upregulates expression of epidermal growth factor- related peptides, but inhibits their proliferative effect in MKN 28 gastric mucosal cells Journal of Clinical Investigation. 101: 1604-1613. PMID 9541490 DOI: 10.1172/Jci1174  1
1997 Cover TL. Genetic diversity in Helicobacter pylori Helicobacter. 2: 108-109. PMID 9432328  1
1997 Cover TL. Commentary: Helicobacter pylori transmission, host factors, and bacterial factors Gastroenterology. 113: S29-30. PMID 9394756 DOI: 10.1016/S0016-5085(97)80007-8  1
1997 Mobley HLT, Cover TL. Helicobacter pylori factors associated with disease development Gastroenterology. 113: S21-S30. PMID 9394755 DOI: 10.1016/S0016-5085(97)80006-6  1
1997 Cover TL, Hanson PI, Heuser JE. Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals its pattern of assembly. The Journal of Cell Biology. 138: 759-69. PMID 9265644 DOI: 10.1083/Jcb.138.4.759  1
1997 Eaton KA, Cover TL, Tummuru MKR, Blaser MJ, Krakowka S. Role of vacuolating cytotoxin in gastritis due to Helicobacter pylori in gnotobiotic piglets Infection and Immunity. 65: 3462-3464. PMID 9234813 DOI: 10.1128/Iai.65.8.3462-3464.1997  1
1997 McGowan CC, Cover TL, Blaser MJ. Analysis of F1F0-ATPase from Helicobacter pylori. Infection and Immunity. 65: 2640-7. PMID 9199431 DOI: 10.1128/Iai.65.7.2640-2647.1997  1
1997 Cao P, Cover TL. High-level genetic diversity in the vapD chromosomal region of Helicobacter pylori Journal of Bacteriology. 179: 2852-2856. PMID 9139899 DOI: 10.1128/Jb.179.9.2852-2856.1997  1
1997 Atherton JC, Peek J, Tham KT, Cover TL, Blaser MJ. Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori Gastroenterology. 112: 92-99. PMID 8978347 DOI: 10.1016/S0016-5085(97)70223-3  1
1997 Cao P, Cover TL. Cloning and expression of a pilB homolog from Helicobacler pylori Clinical Infectious Diseases. 25: 427.  1
1996 Smoot DT, Resau JH, Earlington MH, Simpson M, Cover TL. Effects of Helicobacter pylori vacuolating cytotoxin on primary cultures of human gastric epithelial cells Gut. 39: 795-799. PMID 9038659 DOI: 10.1136/Gut.39.6.795  1
1996 Garner JA, Cover TL. Binding and internalization of the Helicobacter pylori vacuolating cytotoxin by epithelial cells. Infection and Immunity. 64: 4197-203. PMID 8926088 DOI: 10.1128/Iai.64.10.4197-4203.1996  1
1996 Cover TL, Blaser MJ. Helicobacter pylori Infection, a paradigm for chronic mucosal inflammation: Pathogenesis and implications for eradication and prevention Advances in Internal Medicine. 41: 85-117. PMID 8903587  1
1996 Harris PR, Cover TL, Crowe DR, Orenstein JM, Graham MF, Blaser MJ, Smith PD. Helicobacter pylori cytotoxin induces vacuolation of primary human mucosal epithelial cells. Infection and Immunity. 64: 4867-71. PMID 8890255 DOI: 10.1128/Iai.64.11.4867-4871.1996  1
1996 Waldum HL, Sandvik AK, Brenna E, Kleveland PM, McGowan CC, Cover TL, Blaser MJ. The gastrin-histamine sequence [5] Gastroenterology. 111: 838-839. PMID 8780600  1
1996 Atherton JC, Tham KT, Peek RM, Cover TL, Blaser MJ. Density of Helicobacter pylori infection in vivo as assessed by quantitative culture and histology Journal of Infectious Diseases. 174: 552-556. PMID 8769613 DOI: 10.1093/Infdis/174.3.552  1
1996 Cover TL. The vacuolating cytotoxin of helicobacter pylori Molecular Microbiology. 20: 241-246. PMID 8733223 DOI: 10.1111/J.1365-2958.1996.Tb02612.X  1
1996 Ricci V, Ciacci C, Zarrilli R, Sommi P, Tummuru MKR, Del Vecchio Blanco C, Bruni CB, Cover TL, Blaser MJ, Romano M. Effect of Helicobacter pylori on gastric epithelial cell migration and proliferation in vitro: Role of VacA and CagA Infection and Immunity. 64: 2829-2833. PMID 8698518 DOI: 10.1128/Iai.64.7.2829-2833.1996  1
1996 McGowan CC, Cover TL, Blaser MJ. Helicobacter pylori and gastric acid: biological and therapeutic implications. Gastroenterology. 110: 926-38. PMID 8608904 DOI: 10.1053/Gast.1996.V110.Pm8608904  1
1995 Garner JA, Cover TL. Analysis of genetic diversity in cytotoxin-producing and non-cytotoxin-producing Helicobacter pylori strains. The Journal of Infectious Diseases. 172: 290-3. PMID 7797934 DOI: 10.1093/Infdis/172.1.290  1
1995 Blaser MJ, Perez-Perez GI, Cover TL, Peek RM, Kleanthous H, Chyou PH, Stemmermann GN, Nomura A. Infection with Helicobacter pylori Strains Possessing cagA Is Associated with an Increased Risk of Developing Adenocarcinoma of the Stomach Cancer Research. 55: 2111-2115. PMID 7743510  1
1995 Peek RM, Miller GG, Tham KT, Perez-Perez GI, Cover TL, Atherton JC, Dunn GD, Blaser MJ. Detection of Helicobacter pylori gene expression in human gastric mucosa Journal of Clinical Microbiology. 33: 28-32. PMID 7699060 DOI: 10.1128/Jcm.33.1.28-32.1995  1
1995 Cover TL, Glupczynski Y, Lage AP, Burette A, Tummuru MK, Perez-Perez GI, Blaser MJ. Serologic detection of infection with cagA+ Helicobacter pylori strains. Journal of Clinical Microbiology. 33: 1496-500. PMID 7650174 DOI: 10.1128/Jcm.33.6.1496-1500.1995  1
1995 Atherton JC, Cao P, Peek RM, Tummuru MKR, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration Journal of Biological Chemistry. 270: 17771-17777. PMID 7629077 DOI: 10.1074/Jbc.270.30.17771  1
1995 Ghiara P, Marchetti M, Blaser MJ, Tummuru MK, Cover TL, Segal ED, Tompkins LS, Rappuoli R. Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease. Infection and Immunity. 63: 4154-60. PMID 7558333 DOI: 10.1128/Iai.63.10.4154-4160.1995  1
1994 Tummuru MKR, Cover TL, Blaser MJ. Mutation of the cytotoxin-associated cagA gene does not affect the vacuolating cytotoxin activity of Helicobacter pylori Infection and Immunity. 62: 2609-2613. PMID 8188385 DOI: 10.1128/Iai.62.6.2609-2613.1994  1
1994 Cover TL, Tummuru MKR, Cao P, Thompson SA, Blaser MJ. Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains Journal of Biological Chemistry. 269: 10566-10573. PMID 8144644  1
1994 McGowan CC, Cover TL, Blaser MJ. The proton pump inhibitor omeprazole inhibits acid survival of Helicobacter pylori by a urease-independent mechanism. Gastroenterology. 107: 738-43. PMID 8076759 DOI: 10.1016/0016-5085(94)90121-X  1
1994 McGowan CC, Cover TL, Blaser MJ. The proton pump inhibitor omeprazole inhibits acid survival of Helicobacter pylori by a urease-independent mechanism. Gastroenterology. 107: 1573-8. PMID 7926527 DOI: 10.1016/0016-5085(94)90582-7  1
1994 Pérez-Pérez GI, Brown WR, Cover TL, Dunn BE, Cao P, Blaser MJ. Correlation between serological and mucosal inflammatory responses to Helicobacter pylori. Clinical and Diagnostic Laboratory Immunology. 1: 325-9. PMID 7496970 DOI: 10.1128/Cdli.1.3.325-329.1994  1
1993 Tummuru MKR, Cover TL, Blaser MJ. Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: Evidence of linkage to cytotoxin production Infection and Immunity. 61: 1799-1809. PMID 8478069 DOI: 10.1128/Iai.61.5.1799-1809.1993  1
1993 Cover TL, Reddy LY, Blaser MJ. Effects of ATPase inhibitors on the response of HeLa cells to Helicobacter pylori vacuolating toxin. Infection and Immunity. 61: 1427-31. PMID 8454346 DOI: 10.1128/Iai.61.4.1427-1431.1993  1
1993 Blaser MJ, Kobayashi K, Cover TL, Cao P, Feurer ID, Perez-Perez GI. Helicobacter pylori infection in Japanese patients with adenocarcinoma of the stomach International Journal of Cancer. 55: 799-802. PMID 8244577 DOI: 10.1002/Ijc.2910550518  1
1993 Cover TL, Cao P, Lind CD, Tham KT, Blaser MJ. Correlation between vacuolating cytotoxin production by Helicobacter pylori isolates in vitro and in vivo Infection and Immunity. 61: 5008-5012. PMID 8225576 DOI: 10.1128/Iai.61.12.5008-5012.1993  1
1992 Cover TL, Blaser MJ. Purification and characterization of the vacuolating toxin from Helicobacter pylori Journal of Biological Chemistry. 267: 10570-10575. PMID 1587837  1
1992 Cover TL, Blaser MJ. Helicobacter pylori and gastroduodenal disease Annual Review of Medicine. 43: 135-145. PMID 1580578 DOI: 10.1146/Annurev.Me.43.020192.001031  1
1992 Cover TL, Cao P, Murthy UK, Sipple MS, Blaser MJ. Serum neutralizing antibody response to the vacuolating cytotoxin of Helicobacter pylori Journal of Clinical Investigation. 90: 913-918. PMID 1522241 DOI: 10.1172/Jci115967  1
1992 Perez-Perez GI, Olivares AZ, Cover TL, Blaser MJ. Characteristics of Helicobacter pylori variants selected for urease deficiency Infection and Immunity. 60: 3658-3663. PMID 1500174 DOI: 10.1128/Iai.60.9.3658-3663.1992  1
1992 Cover TL, Vaughn SG, Cao P, Blaser MJ. Potentiation of Helicobacter pylori vacuolating toxin activity by nicotine and other weak bases Journal of Infectious Diseases. 166: 1073-1078. PMID 1402018 DOI: 10.1093/Infdis/166.5.1073  1
1992 Cover TL, Halter SA, Blaser MJ. Characterization of Hela cell vacuoles induced by Helicobacter pylori broth culture supernatant Human Pathology. 23: 1004-1010. PMID 1381332 DOI: 10.1016/0046-8177(92)90261-Z  1
1992 Cheng RT, Mc Dermott HJ, Gia GM, Cover TL, Duda MM. ExDosures to Refractorv Ceramic Fiber in Refineries and Chemical Plants Applied Occupational and Environmental Hygiene. 7: 361-367. DOI: 10.1080/1047322X.1992.10390173  1
1991 Cover TL, Puryear W, Perez-Perez GI, Blaser MJ. Effect of urease on HeLa cell vacuolation induced by Helicobacter pylori cytotoxin Infection and Immunity. 59: 1264-1270. PMID 2004808 DOI: 10.1128/Iai.59.4.1264-1270.1991  1
1990 Cover TL, Dooley CP, Blaser MJ. Characterization of and human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity Infection and Immunity. 58: 603-610. PMID 2307514 DOI: 10.1128/Iai.58.3.603-610.1990  1
1990 Cover TL, Perez-Perez GI, Blaser MJ. Evaluation of cytotoxic activity in fecal filtrates from patients with Campylobacter jejuni or Campylobacter coli enteritis Fems Microbiology Letters. 70: 301-304. PMID 2227365 DOI: 10.1111/J.1574-6968.1990.Tb13993.X  1
1989 Cover TL, Aber RC. Yersinia enterocolitica New England Journal of Medicine. 321: 16-24. PMID 2659991  1
1989 Cover TL, Blaser MJ. The pathobiology of Campylobacter infections in humans Annual Review of Medicine. 40: 269-285. PMID 2658752 DOI: 10.1146/Annurev.Me.40.020189.001413  1
1988 Cover TL, Appelbaum PC, Aber RC. Pseudomonas paucimobilis empyema after cardiac transplantation Southern Medical Journal. 81: 796-798. PMID 3287645  1
1973 Cover TL. STEAM-HYDRAULIC LOCOMOTIVE. (A PRACTICAL MEANS OF RE-EMPLOYING COAL AS A TRANSPORTATION INDUSTRY FUEL) American Society of Mechanical Engineers (Paper) 1
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