Garry P. Nolan - Publications

Stanford University, Palo Alto, CA 
Molecular Biology, Microbiology Biology

196 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Baskar R, Fienberg HG, Khair Z, Favaro P, Kimmey S, Green DR, Nolan GP, Plevritis S, Bendall SC. TRAIL-induced variation of cell signaling states provides nonheritable resistance to apoptosis. Life Science Alliance. 2. PMID 31704709 DOI: 10.26508/lsa.201900554  0.48
2019 Ding X, Krutzik PO, Ghaffari AA, Zhaozhi Y, Miranda D, Cheng G, Ho CM, Nolan GP, Sanchez DJ. Cellular Signaling Analysis shows antiviral, ribavirin-mediated ribosomal signaling modulation. Antiviral Research. 104598. PMID 31513822 DOI: 10.1016/j.antiviral.2019.104598  0.92
2019 Hartmann FJ, Simonds EF, Vivanco N, Bruce T, Borges L, Nolan GP, Spitzer MH, Bendall SC. Scalable Conjugation and Characterization of Immunoglobulins with Stable Mass Isotope Reporters for Single-Cell Mass Cytometry Analysis. Methods in Molecular Biology (Clifton, N.J.). 1989: 55-81. PMID 31077099 DOI: 10.1007/978-1-4939-9454-0_5  0.48
2019 Good Z, Borges L, Vivanco Gonzalez N, Sahaf B, Samusik N, Tibshirani R, Nolan GP, Bendall SC. Proliferation tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells. Nature Biotechnology. PMID 30742126 DOI: 10.1038/s41587-019-0033-2  0.48
2019 Knapp DJHF, Hammond CA, Wang F, Aghaeepour N, Miller PH, Beer PA, Pellacani D, VanInsberghe M, Hansen C, Bendall SC, Nolan GP, Eaves CJ. A topological view of human CD34+ cell state trajectories from integrated single-cell output and proteomic data. Blood. PMID 30622121 DOI: 10.1182/blood-2018-10-878025  0.48
2018 Han G, Spitzer MH, Bendall SC, Fantl WJ, Nolan GP. Metal-isotope-tagged monoclonal antibodies for high-dimensional mass cytometry. Nature Protocols. PMID 30258176 DOI: 10.1038/s41596-018-0016-7  0.48
2018 Aghaeepour N, Simonds EF, Knapp DJHF, Bruggner R, Sachs K, Culos A, Gherardini PF, Samusik N, Fragiadakis G, Bendall S, Gaudilliere B, Angst MS, Eaves CJ, Weiss WA, Fantl W, ... Nolan G, et al. GateFinder: Projection-based Gating Strategy Optimization for Flow and Mass Cytometry. Bioinformatics (Oxford, England). PMID 29850785 DOI: 10.1093/bioinformatics/bty430  0.32
2018 Anchang B, Davis KL, Fienberg HG, Williamson BD, Bendall SC, Karacosta LG, Tibshirani R, Nolan GP, Plevritis SK. DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity. Proceedings of the National Academy of Sciences of the United States of America. PMID 29654148 DOI: 10.1073/pnas.1711365115  0.48
2018 Porpiglia E, Samusik N, Van Ho AT, Cosgrove BD, Mai T, Davis KL, Jager A, Nolan GP, Bendall SC, Fantl WJ, Blau HM. Publisher Correction: High-resolution myogenic lineage mapping by single-cell mass cytometry. Nature Cell Biology. PMID 29507406 DOI: 10.1038/s41556-018-0043-1  0.48
2018 Good Z, Sarno J, Jager A, Samusik N, Aghaeepour N, Simonds EF, White L, Lacayo NJ, Fantl WJ, Fazio G, Gaipa G, Biondi A, Tibshirani R, Bendall SC, Nolan GP, et al. Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse. Nature Medicine. PMID 29505032 DOI: 10.1038/nm.4505  0.48
2017 Porpiglia E, Samusik N, Van Ho AT, Cosgrove BD, Mai T, Davis KL, Jager A, Nolan GP, Bendall SC, Fantl WJ, Blau HM. High-resolution myogenic lineage mapping by single-cell mass cytometry. Nature Cell Biology. PMID 28414312 DOI: 10.1038/ncb3507  0.48
2017 Spitzer MH, Carmi Y, Reticker-Flynn NE, Kwek SS, Madhireddy D, Martins MM, Gherardini PF, Prestwood TR, Chabon J, Bendall SC, Fong L, Nolan GP, Engleman EG. Systemic Immunity Is Required for Effective Cancer Immunotherapy. Cell. PMID 28111070 DOI: 10.1016/j.cell.2016.12.022  0.48
2016 Knapp DJ, Hammond CA, Aghaeepour N, Miller PH, Pellacani D, Beer PA, Sachs K, Qiao W, Wang W, Humphries RK, Sauvageau G, Zandstra PW, Bendall SC, Nolan GP, Hansen C, et al. Distinct signaling programs control human hematopoietic stem cell survival and proliferation. Blood. PMID 27827829 DOI: 10.1182/blood-2016-09-740654  0.48
2016 Inoue S, Li WY, Tseng A, Beerman I, Elia AJ, Bendall SC, Lemonnier F, Kron KJ, Cescon DW, Hao Z, Lind EF, Takayama N, Planello AC, Shen SY, Shih AH, ... ... Nolan GP, et al. Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2. Cancer Cell. PMID 27424808 DOI: 10.1016/j.ccell.2016.05.018  0.48
2016 Anchang B, Hart TD, Bendall SC, Qiu P, Bjornson Z, Linderman M, Nolan GP, Plevritis SK. Visualization and cellular hierarchy inference of single-cell data using SPADE. Nature Protocols. 11: 1264-1279. PMID 27310265 DOI: 10.1038/nprot.2016.066  0.48
2016 Spitzer MH, Nolan GP. Mass Cytometry: Single Cells, Many Features. Cell. 165: 780-91. PMID 27153492 DOI: 10.1016/j.cell.2016.04.019  1
2016 Hotson AN, Gopinath S, Nicolau M, Khasanova A, Finck R, Monack D, Nolan GP. Coordinate actions of innate immune responses oppose those of the adaptive immune system during Salmonella infection of mice. Science Signaling. 9: ra4. PMID 26758212 DOI: 10.1126/scisignal.aaa9303  1
2015 Spitzer MH, Gherardini PF, Fragiadakis GK, Bhattacharya N, Yuan RT, Hotson AN, Finck R, Carmi Y, Zunder ER, Fantl WJ, Bendall SC, Engleman EG, Nolan GP. IMMUNOLOGY. An interactive reference framework for modeling a dynamic immune system. Science (New York, N.Y.). 349: 1259425. PMID 26160952 DOI: 10.1126/science.1259425  1
2015 Levine JH, Simonds EF, Bendall SC, Davis KL, Amir ED, Tadmor MD, Litvin O, Fienberg HG, Jager A, Zunder ER, Finck R, Gedman AL, Radtke I, Downing JR, Pe'er D, ... Nolan GP, et al. Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis. Cell. PMID 26095251 DOI: 10.1016/j.cell.2015.05.047  1
2015 Behbehani GK, Samusik N, Bjornson ZB, Fantl WJ, Medeiros BC, Nolan GP. Mass Cytometric Functional Profiling of Acute Myeloid Leukemia Defines Cell-Cycle and Immunophenotypic Properties That Correlate with Known Responses to Therapy. Cancer Discovery. 5: 988-1003. PMID 26091827 DOI: 10.1158/2159-8290.CD-15-0298  1
2015 ElSohly AM, Netirojjanakul C, Aanei IL, Jager A, Bendall S, Farkas ME, Nolan GP, Francis MB. Synthetically Modified Viral Capsids as Versatile Carriers for Use in Antibody-based Cell Targeting. Bioconjugate Chemistry. PMID 26076186 DOI: 10.1021/acs.bioconjchem.5b00226  0.48
2015 O'Gorman WE, Hsieh EW, Savig ES, Gherardini PF, Hernandez JD, Hansmann L, Balboni IM, Utz PJ, Bendall SC, Fantl WJ, Lewis DB, Nolan GP, Davis MM. Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus. The Journal of Allergy and Clinical Immunology. PMID 26037552 DOI: 10.1016/j.jaci.2015.04.008  1
2015 Nair N, Mei HE, Chen SY, Hale M, Nolan GP, Maecker HT, Genovese M, Fathman CG, Whiting CC. Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy. Arthritis Research & Therapy. 17: 127. PMID 25981462 DOI: 10.1186/s13075-015-0644-z  1
2015 Kubagawa H, Carroll MC, Jacob CO, Lang KS, Lee KH, Mak T, McAndrews M, Morse HC, Nolan GP, Ohno H, Richter GH, Seal R, Wang JY, Wiestner A, Coligan JE. Nomenclature of Toso, Fas apoptosis inhibitory molecule 3, and IgM FcR. Journal of Immunology (Baltimore, Md. : 1950). 194: 4055-7. PMID 25888699 DOI: 10.4049/jimmunol.1500222  1
2015 Lujan E, Zunder ER, Ng YH, Goronzy IN, Nolan GP, Wernig M. Early reprogramming regulators identified by prospective isolation and mass cytometry. Nature. 521: 352-6. PMID 25830878 DOI: 10.1038/nature14274  1
2015 Nishikii H, Kanazawa Y, Umemoto T, Goltsev Y, Matsuzaki Y, Matsushita K, Yamato M, Nolan GP, Negrin R, Chiba S. Unipotent Megakaryopoietic Pathway Bridging Hematopoietic Stem Cells and Mature Megakaryocytes. Stem Cells (Dayton, Ohio). 33: 2196-207. PMID 25753067 DOI: 10.1002/stem.1985  1
2015 Zunder ER, Lujan E, Goltsev Y, Wernig M, Nolan GP. A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry. Cell Stem Cell. 16: 323-37. PMID 25748935 DOI: 10.1016/j.stem.2015.01.015  1
2015 Zunder ER, Finck R, Behbehani GK, Amir el-AD, Krishnaswamy S, Gonzalez VD, Lorang CG, Bjornson Z, Spitzer MH, Bodenmiller B, Fantl WJ, Pe'er D, Nolan GP. Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm. Nature Protocols. 10: 316-33. PMID 25612231 DOI: 10.1038/nprot.2015.020  1
2015 McIlwain DR, Grusdat M, Pozdeev VI, Xu HC, Shinde P, Reardon C, Hao Z, Beyer M, Bergthaler A, Häussinger D, Nolan GP, Lang KS, Lang PA. T-cell STAT3 is required for the maintenance of humoral immunity to LCMV. European Journal of Immunology. 45: 418-27. PMID 25393615 DOI: 10.1002/eji.201445060  1
2015 Gaudillière B, Ganio EA, Tingle M, Lancero HL, Fragiadakis GK, Baca QJ, Aghaeepour N, Wong RJ, Quaintance C, El-Sayed YY, Shaw GM, Lewis DB, Stevenson DK, Nolan GP, Angst MS. Implementing Mass Cytometry at the Bedside to Study the Immunological Basis of Human Diseases: Distinctive Immune Features in Patients with a History of Term or Preterm Birth Cytometry Part A. DOI: 10.1002/cyto.a.22720  1
2014 Mingueneau M, Krishnaswamy S, Spitzer MH, Bendall SC, Stone EL, Hedrick SM, Pe'er D, Mathis D, Nolan GP, Benoist C. Single-cell mass cytometry of TCR signaling: amplification of small initial differences results in low ERK activation in NOD mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 16466-71. PMID 25362052 DOI: 10.1073/pnas.1419337111  1
2014 Krishnaswamy S, Spitzer MH, Mingueneau M, Bendall SC, Litvin O, Stone E, Pe'er D, Nolan GP. Systems biology. Conditional density-based analysis of T cell signaling in single-cell data. Science (New York, N.Y.). 346: 1250689. PMID 25342659 DOI: 10.1126/science.1250689  0.48
2014 Sachs Z, LaRue RS, Nguyen HT, Sachs K, Noble KE, Mohd Hassan NA, Diaz-Flores E, Rathe SK, Sarver AL, Bendall SC, Ha NA, Diers MD, Nolan GP, Shannon KM, Largaespada DA. NRASG12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia. Blood. 124: 3274-83. PMID 25316678 DOI: 10.1182/blood-2013-08-521708  1
2014 Behbehani GK, Thom C, Zunder ER, Finck R, Gaudilliere B, Fragiadakis GK, Fantl WJ, Nolan GP. Transient partial permeabilization with saponin enables cellular barcoding prior to surface marker staining. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 85: 1011-9. PMID 25274027 DOI: 10.1002/cyto.a.22573  1
2014 Gaudillière B, Fragiadakis GK, Bruggner RV, Nicolau M, Finck R, Tingle M, Silva J, Ganio EA, Yeh CG, Maloney WJ, Huddleston JI, Goodman SB, Davis MM, Bendall SC, Fantl WJ, ... ... Nolan GP, et al. Clinical recovery from surgery correlates with single-cell immune signatures. Science Translational Medicine. 6: 255ra131. PMID 25253674 DOI: 10.1126/scitranslmed.3009701  1
2014 Fienberg HG, Nolan GP. High-dimensional cytometry. Preface. Current Topics in Microbiology and Immunology. 377: vii-viii. PMID 25118348  1
2014 Sen N, Mukherjee G, Sen A, Bendall SC, Sung P, Nolan GP, Arvin AM. Single-cell mass cytometry analysis of human tonsil T cell remodeling by varicella zoster virus. Cell Reports. 8: 633-45. PMID 25043183 DOI: 10.1016/j.celrep.2014.06.024  1
2014 Pyne S, Lee SX, Wang K, Irish J, Tamayo P, Nazaire MD, Duong T, Ng SK, Hafler D, Levy R, Nolan GP, Mesirov J, McLachlan GJ. Joint modeling and registration of cell populations in cohorts of high-dimensional flow cytometric data. Plos One. 9: e100334. PMID 24983991 DOI: 10.1371/journal.pone.0100334  1
2014 Bruggner RV, Bodenmiller B, Dill DL, Tibshirani RJ, Nolan GP. Automated identification of stratifying signatures in cellular subpopulations. Proceedings of the National Academy of Sciences of the United States of America. 111: E2770-7. PMID 24979804 DOI: 10.1073/pnas.1408792111  1
2014 Bendall SC, Davis KL, Amir el-AD, Tadmor MD, Simonds EF, Chen TJ, Shenfeld DK, Nolan GP, Pe'er D. Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. Cell. 157: 714-25. PMID 24766814 DOI: 10.1016/j.cell.2014.04.005  1
2014 Angelo M, Bendall SC, Finck R, Hale MB, Hitzman C, Borowsky AD, Levenson RM, Lowe JB, Liu SD, Zhao S, Natkunam Y, Nolan GP. Multiplexed ion beam imaging of human breast tumors. Nature Medicine. 20: 436-42. PMID 24584119 DOI: 10.1038/nm.3488  1
2014 Fienberg HG, Nolan GP. Mass cytometry to decipher the mechanism of nongenetic drug resistance in cancer. Current Topics in Microbiology and Immunology. 377: 85-94. PMID 24578267 DOI: 10.1007/82_2014_365  1
2014 Wolchinsky R, Hod-Marco M, Oved K, Shen-Orr SS, Bendall SC, Nolan GP, Reiter Y. Antigen-dependent integration of opposing proximal TCR-signaling cascades determines the functional fate of T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 192: 2109-19. PMID 24489091 DOI: 10.4049/jimmunol.1301142  1
2014 Krishnaswamy S, Spitzer MH, Mingueneau M, Bendall SC, Litvin O, Stone E, Pe'Er D, Nolan GP. Conditional density-based analysis of T cell signaling in single-cell data Science. 346. DOI: 10.1126/science/1250689  1
2013 Kinoshita SM, Kogure A, Taguchi S, Nolan GP. Snapin, positive regulator of stimulation- induced Ca²⁺ release through RyR, is necessary for HIV-1 replication in T cells. Plos One. 8: e75297. PMID 24130701 DOI: 10.1371/journal.pone.0075297  1
2013 Bjornson ZB, Nolan GP, Fantl WJ. Single-cell mass cytometry for analysis of immune system functional states. Current Opinion in Immunology. 25: 484-94. PMID 23999316 DOI: 10.1016/j.coi.2013.07.004  1
2013 Amir el-AD, Davis KL, Tadmor MD, Simonds EF, Levine JH, Bendall SC, Shenfeld DK, Krishnaswamy S, Nolan GP, Pe'er D. viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia. Nature Biotechnology. 31: 545-52. PMID 23685480 DOI: 10.1038/nbt.2594  1
2013 Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C, Best AJ, et al. The transcriptional landscape of αβ T cell differentiation. Nature Immunology. 14: 619-32. PMID 23644507 DOI: 10.1038/ni.2590  1
2013 Finck R, Simonds EF, Jager A, Krishnaswamy S, Sachs K, Fantl W, Pe'er D, Nolan GP, Bendall SC. Normalization of mass cytometry data with bead standards. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 483-94. PMID 23512433 DOI: 10.1002/cyto.a.22271  1
2013 Lang KS, Lang PA, Meryk A, Pandyra AA, Boucher LM, Pozdeev VI, Tusche MW, Göthert JR, Haight J, Wakeham A, You-Ten AJ, McIlwain DR, Merches K, Khairnar V, Recher M, ... Nolan GP, et al. Involvement of Toso in activation of monocytes, macrophages, and granulocytes. Proceedings of the National Academy of Sciences of the United States of America. 110: 2593-8. PMID 23359703 DOI: 10.1073/pnas.1222264110  1
2013 Sachs K, Itani S, Fitzgerald J, Schoeberl B, Nolan GP, Tomlin CJ. Single timepoint models of dynamic systems Interface Focus. 3. DOI: 10.1098/rsfs.2013.0019  1
2013 Krzywinski M, Savig E, Nolan GP. Points of view: Multidimensional data Nature Methods. 10: 595. DOI: 10.1038/nmeth.2531  1
2012 Kinoshita SM, Krutzik PO, Nolan GP. COP9 signalosome component JAB1/CSN5 is necessary for T cell signaling through LFA-1 and HIV-1 replication. Plos One. 7: e41725. PMID 22911848 DOI: 10.1371/journal.pone.0041725  1
2012 Bodenmiller B, Zunder ER, Finck R, Chen TJ, Savig ES, Bruggner RV, Simonds EF, Bendall SC, Sachs K, Krutzik PO, Nolan GP. Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators. Nature Biotechnology. 30: 858-67. PMID 22902532 DOI: 10.1038/nbt.2317  1
2012 Linderman MD, Bjornson Z, Simonds EF, Qiu P, Bruggner RV, Sheode K, Meng TH, Plevritis SK, Nolan GP. CytoSPADE: high-performance analysis and visualization of high-dimensional cytometry data. Bioinformatics (Oxford, England). 28: 2400-1. PMID 22782546 DOI: 10.1093/bioinformatics/bts425  1
2012 Bendall SC, Nolan GP. From single cells to deep phenotypes in cancer. Nature Biotechnology. 30: 639-47. PMID 22781693 DOI: 10.1038/nbt.2283  1
2012 Behbehani GK, Bendall SC, Clutter MR, Fantl WJ, Nolan GP. Single-cell mass cytometry adapted to measurements of the cell cycle. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 552-66. PMID 22693166 DOI: 10.1002/cyto.a.22075  1
2012 Fienberg HG, Simonds EF, Fantl WJ, Nolan GP, Bodenmiller B. A platinum-based covalent viability reagent for single-cell mass cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 467-75. PMID 22577098 DOI: 10.1002/cyto.a.22067  1
2012 Bendall SC, Nolan GP, Roederer M, Chattopadhyay PK. A deep profiler's guide to cytometry. Trends in Immunology. 33: 323-32. PMID 22476049 DOI: 10.1016/  1
2012 Schulz KR, Danna EA, Krutzik PO, Nolan GP. Single-cell phospho-protein analysis by flow cytometry. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 8.17.1-20. PMID 22314834 DOI: 10.1002/0471142735.im0817s96  1
2012 Gibbs KD, Jager A, Crespo O, Goltsev Y, Trejo A, Richard CE, Nolan GP. Decoupling of tumor-initiating activity from stable immunophenotype in HoxA9-Meis1-driven AML. Cell Stem Cell. 10: 210-7. PMID 22305570 DOI: 10.1016/j.stem.2012.01.004  1
2012 Newell EW, Sigal N, Bendall SC, Nolan GP, Davis MM. Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes. Immunity. 36: 142-52. PMID 22265676 DOI: 10.1016/j.immuni.2012.01.002  1
2012 Gibbs KD, Jager A, Crespo O, Goltsev Y, Trejo A, Richard CE, Nolan GP. Decoupling of tumor-initiating activity from stable immunophenotype in HoxA9-Meis1-driven AML (Cell Stem Cell (2012) 10, (210-217)) Cell Stem Cell. 10: 480. DOI: 10.1016/j.stem.2012.02.019  1
2011 Zhang B, Ng D, Jones C, Oh ST, Nolan GP, Salehi S, Wong W, Zehnder JL, Gotlib J. A novel splice donor mutation in the thrombopoietin gene leads to exon 2 skipping in a Filipino family with hereditary thrombocythemia. Blood. 118: 6988-90. PMID 22194398 DOI: 10.1182/blood-2011-10-386177  1
2011 Nolan GP. Flow cytometry in the post fluorescence era. Best Practice & Research. Clinical Haematology. 24: 505-8. PMID 22127312 DOI: 10.1016/j.beha.2011.09.005  1
2011 Palazzo AL, Evensen E, Huang YW, Cesano A, Nolan GP, Fantl WJ. Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells Plos One. 6. PMID 22016760 DOI: 10.1371/journal.pone.0024592  1
2011 Qiu P, Simonds EF, Bendall SC, Gibbs KD, Bruggner RV, Linderman MD, Sachs K, Nolan GP, Plevritis SK. Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. Nature Biotechnology. 29: 886-91. PMID 21964415 DOI: 10.1038/nbt.1991  1
2011 Knijnenburg TA, Roda O, Wan Y, Nolan GP, Aitchison JD, Shmulevich I. A regression model approach to enable cell morphology correction in high-throughput flow cytometry. Molecular Systems Biology. 7: 531. PMID 21952134 DOI: 10.1038/msb.2011.64  1
2011 Heffner GC, Clutter MR, Nolan GP, Weissman IL. Novel hematopoietic progenitor populations revealed by direct assessment of GATA1 protein expression and cMPL signaling events. Stem Cells (Dayton, Ohio). 29: 1774-82. PMID 21898686 DOI: 10.1002/stem.719  1
2011 Thomas C, Moraga I, Levin D, Krutzik PO, Podoplelova Y, Trejo A, Lee C, Yarden G, Vleck SE, Glenn JS, Nolan GP, Piehler J, Schreiber G, Garcia KC. Structural linkage between ligand discrimination and receptor activation by type I interferons. Cell. 146: 621-32. PMID 21854986 DOI: 10.1016/j.cell.2011.06.048  1
2011 Bendall SC, Simonds EF, Qiu P, Amir el-AD, Krutzik PO, Finck R, Bruggner RV, Melamed R, Trejo A, Ornatsky OI, Balderas RS, Plevritis SK, Sachs K, Pe'er D, Tanner SD, ... Nolan GP, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science (New York, N.Y.). 332: 687-96. PMID 21551058 DOI: 10.1126/science.1198704  1
2011 Gibbs KD, Gilbert PM, Sachs K, Zhao F, Blau HM, Weissman IL, Nolan GP, Majeti R. Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments. Blood. 117: 4226-33. PMID 21357764 DOI: 10.1182/blood-2010-07-298232  1
2011 Schadt EE, Linderman MD, Sorenson J, Lee L, Nolan GP. Cloud and heterogeneous computing solutions exist today for the emerging big data problems in biology. Nature Reviews. Genetics. 12: 224. PMID 21301474 DOI: 10.1038/nrg2857-c2  1
2011 Krutzik PO, Clutter MR, Trejo A, Nolan GP. Fluorescent cell barcoding for multiplex flow cytometry. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 6.31. PMID 21207359 DOI: 10.1002/0471142956.cy0631s55  1
2011 Krutzik PO, Trejo A, Schulz KR, Nolan GP. Phospho flow cytometry methods for the analysis of kinase signaling in cell lines and primary human blood samples. Methods in Molecular Biology (Clifton, N.J.). 699: 179-202. PMID 21116984 DOI: 10.1007/978-1-61737-950-5_9  1
2010 Sathaliyawala T, O'Gorman WE, Greter M, Bogunovic M, Konjufca V, Hou ZE, Nolan GP, Miller MJ, Merad M, Reizis B. Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling. Immunity. 33: 597-606. PMID 20933441 DOI: 10.1016/j.immuni.2010.09.012  1
2010 Katzman SD, O'Gorman WE, Villarino AV, Gallo E, Friedman RS, Krummel MF, Nolan GP, Abbas AK. Duration of antigen receptor signaling determines T-cell tolerance or activation. Proceedings of the National Academy of Sciences of the United States of America. 107: 18085-90. PMID 20921406 DOI: 10.1073/pnas.1010560107  1
2010 Clutter MR, Heffner GC, Krutzik PO, Sachen KL, Nolan GP. Tyramide signal amplification for analysis of kinase activity by intracellular flow cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 1020-31. PMID 20824632 DOI: 10.1002/cyto.a.20970  1
2010 Rosen DB, Putta S, Covey T, Huang YW, Nolan GP, Cesano A, Minden MD, Fantl WJ. Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia. Plos One. 5: e12405. PMID 20811632 DOI: 10.1371/journal.pone.0012405  1
2010 Schadt EE, Linderman MD, Sorenson J, Lee L, Nolan GP. Computational solutions to large-scale data management and analysis. Nature Reviews. Genetics. 11: 647-57. PMID 20717155 DOI: 10.1038/nrg2857  1
2010 O'Gorman WE, Sampath P, Simonds EF, Sikorski R, O'Malley M, Krutzik PO, Chen H, Panchanathan V, Chaudhri G, Karupiah G, Lewis DB, Thorne SH, Nolan GP. Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses. Cell Host & Microbe. 8: 174-85. PMID 20709294 DOI: 10.1016/j.chom.2010.07.008  1
2010 Irish JM, Myklebust JH, Alizadeh AA, Houot R, Sharman JP, Czerwinski DK, Nolan GP, Levy R. B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 107: 12747-54. PMID 20543139 DOI: 10.1073/pnas.1002057107  1
2010 Maecker HT, Nolan GP, Fathman CG. New technologies for autoimmune disease monitoring. Current Opinion in Endocrinology, Diabetes, and Obesity. 17: 322-8. PMID 20531181 DOI: 10.1097/MED.0b013e32833ada91  1
2010 Oh ST, Simonds EF, Jones C, Hale MB, Goltsev Y, Gibbs KD, Merker JD, Zehnder JL, Nolan GP, Gotlib J. Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms. Blood. 116: 988-92. PMID 20404132 DOI: 10.1182/blood-2010-02-270108  1
2010 Rauen KA, Schoyer L, McCormick F, Lin AE, Allanson JE, Stevenson DA, Gripp KW, Neri G, Carey JC, Legius E, Tartaglia M, Schubbert S, Roberts AE, Gelb BD, Shannon K, ... ... Nolan GP, et al. Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back. American Journal of Medical Genetics. Part A. 152: 4-24. PMID 20014119 DOI: 10.1002/ajmg.a.33183  1
2010 Linderman MD, Bruggner R, Athalye V, Meng TH, Bani Asadi N, Nolan GP. High-throughput Bayesian network learning using heterogeneous multicore computers Proceedings of the International Conference On Supercomputing. 95-104. DOI: 10.1145/1810085.1810101  1
2010 Bani Asadi N, Fletcher CW, Gibeling G, Wawrzynek J, Wong WH, Nolan GP, Glass EN, Sachs K, Burke D, Zhou Z. ParaLearn: A massively parallel, scalable system for learning interaction networks on FPGAs Proceedings of the International Conference On Supercomputing. 83-94. DOI: 10.1145/1810085.1810100  1
2010 Linderman MD, Ho M, Dill DL, Meng TH, Nolan GP. Towards program optimization through automated analysis of numerical precision Proceedings of the 2010 Cgo - the 8th International Symposium On Code Generation and Optimization. 230-237. DOI: 10.1145/1772954.1772987  1
2010 Krutzik PO, Bendall SC, Hale MB, Irish JM, Nolan GP. Phospho Flow Cytometry: Single-Cell Signaling Networks in Next-Generation Drug Discovery and Patient Stratification Flow Cytometry in Drug Discovery and Development. 303-334. DOI: 10.1002/9780470910085.ch15  1
2009 Sachs K, Gentles AJ, Youland R, Itani S, Irish J, Nolan GP, Plevritis SK. Characterization of patient specific signaling via augmentation of Bayesian networks with disease and patient state nodes. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 6624-7. PMID 19963681 DOI: 10.1109/IEMBS.2009.5332563  1
2009 Hale MB, Krutzik PO, Samra SS, Crane JM, Nolan GP. Stage dependent aberrant regulation of cytokine-STAT signaling in murine systemic lupus erythematosus. Plos One. 4: e6756. PMID 19707593 DOI: 10.1371/journal.pone.0006756  1
2009 O'Gorman WE, Dooms H, Thorne SH, Kuswanto WF, Simonds EF, Krutzik PO, Nolan GP, Abbas AK. The initial phase of an immune response functions to activate regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 332-9. PMID 19542444 DOI: 10.4049/jimmunol.0900691  1
2009 Hotson AN, Hardy JW, Hale MB, Contag CH, Nolan GP. The T cell STAT signaling network is reprogrammed within hours of bacteremia via secondary signals. Journal of Immunology (Baltimore, Md. : 1950). 182: 7558-68. PMID 19494279 DOI: 10.4049/jimmunol.0803666  1
2009 Shachaf CM, Elchuri SV, Koh AL, Zhu J, Nguyen LN, Mitchell DJ, Zhang J, Swartz KB, Sun L, Chan S, Sinclair R, Nolan GP. A novel method for detection of phosphorylation in single cells by surface enhanced Raman scattering (SERS) using composite organic-inorganic nanoparticles (COINs). Plos One. 4: e5206. PMID 19367337 DOI: 10.1371/journal.pone.0005206  1
2009 Almogy G, Nolan GP. Conditional protein stabilization via the small molecules Shld-1 and rapamycin increases the signal-to-noise ratio with tet-inducible gene expression. Biotechniques. 46: 44-50. PMID 19301621 DOI: 10.2144/000113030  1
2009 Sachs K, Itani S, Fitzgerald J, Wille L, Schoeberl B, Dahleh MA, Nolan GP. Learning cyclic signaling pathway structures while minimizing data requirements Pacific Symposium On Biocomputing 2009, Psb 2009. 63-74. PMID 19209696  1
2009 Sachs K, Itani S, Carlisle J, Nolan GP, Pe'er D, Lauffenburger DA. Learning signaling network structures with sparsely distributed data. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 16: 201-12. PMID 19193145 DOI: 10.1089/cmb.2008.07TT  1
2009 Hammer MM, Kotecha N, Irish JM, Nolan GP, Krutzik PO. WebFlow: a software package for high-throughput analysis of flow cytometry data. Assay and Drug Development Technologies. 7: 44-55. PMID 19187010 DOI: 10.1089/adt.2008.174  1
2008 Koh AL, Shachaf CM, Elchuri S, Nolan GP, Sinclair R. Electron microscopy localization and characterization of functionalized composite organic-inorganic SERS nanoparticles on leukemia cells. Ultramicroscopy. 109: 111-21. PMID 18995965 DOI: 10.1016/j.ultramic.2008.09.004  1
2008 Kotecha N, Flores NJ, Irish JM, Simonds EF, Sakai DS, Archambeault S, Diaz-Flores E, Coram M, Shannon KM, Nolan GP, Loh ML. Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell. 14: 335-43. PMID 18835035 DOI: 10.1016/j.ccr.2008.08.014  1
2008 Shachaf CM, Gentles AJ, Elchuri S, Sahoo D, Soen Y, Sharpe O, Perez OD, Chang M, Mitchel D, Robinson WH, Dill D, Nolan GP, Plevritis SK, Felsher DW. Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance Cancer Research. 68: 5132-5142. PMID 18593912 DOI: 10.1158/0008-5472.CAN-07-6192  1
2008 Lee AW, Sharp ER, O'Mahony A, Rosenberg MG, Israelski DM, Nolan GP, Nixon DF. Single-cell, phosphoepitope-specific analysis demonstrates cell type- and pathway-specific dysregulation of Jak/STAT and MAPK signaling associated with in vivo human immunodeficiency virus type 1 infection. Journal of Virology. 82: 3702-12. PMID 18216116 DOI: 10.1128/JVI.01582-07  1
2008 Krutzik PO, Crane JM, Clutter MR, Nolan GP. High-content single-cell drug screening with phosphospecific flow cytometry. Nature Chemical Biology. 4: 132-42. PMID 18157122 DOI: 10.1038/nchembio.2007.59  0.92
2008 Itani S, Sachs K, Nolan GP, Dahleh MA. Structure learning for biomolecular pathways containing cycles 8th Ieee International Conference On Bioinformatics and Bioengineering, Bibe 2008. DOI: 10.1109/BIBE.2008.4696729  1
2008 Koh AL, Shachaf CM, Elchuri S, Nolan GP, Sinclair R. Electron microscopy characterization of Composite Organic-Inorganic Nanoparticles (COINs) as Raman labels for extra-cellular analyses Microscopy and Microanalysis. 14: 670-671. DOI: 10.1017/S1431927608082664  1
2007 Schulz KR, Danna EA, Krutzik PO, Nolan GP. Single-cell phospho-protein analysis by flow cytometry. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 8.17. PMID 18432997 DOI: 10.1002/0471142735.im0817s78  0.92
2007 Shachaf CM, Perez OD, Youssef S, Fan AC, Elchuri S, Goldstein MJ, Shirer AE, Sharpe O, Chen J, Mitchell DJ, Chang M, Nolan GP, Steinman L, Felsher DW. Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis. Blood. 110: 2674-84. PMID 17622571 DOI: 10.1182/blood-2006-09-048033  1
2007 Nolan GP. What's wrong with drug screening today. Nature Chemical Biology. 3: 187-91. PMID 17372598 DOI: 10.1038/nchembio0407-187  1
2007 Lehár J, Zimmermann GR, Krueger AS, Molnar RA, Ledell JT, Heilbut AM, Short GF, Giusti LC, Nolan GP, Magid OA, Lee MS, Borisy AA, Stockwell BR, Keith CT. Chemical combination effects predict connectivity in biological systems. Molecular Systems Biology. 3: 80. PMID 17332758 DOI: 10.1038/msb4100116  1
2007 Perez OD, Mitchell D, Nolan GP. Differential role of ICAM ligands in determination of human memory T cell differentiation Bmc Immunology. 8. PMID 17233909 DOI: 10.1186/1471-2172-8-2  1
2007 Van Meter ME, Díaz-Flores E, Archard JA, Passegué E, Irish JM, Kotecha N, Nolan GP, Shannon K, Braun BS. K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells. Blood. 109: 3945-52. PMID 17192389 DOI: 10.1182/blood-2006-09-047530  1
2007 Zampieri CA, Fortin JF, Nolan GP, Nabel GJ. The ERK mitogen-activated protein kinase pathway contributes to Ebola virus glycoprotein-induced cytotoxicity. Journal of Virology. 81: 1230-40. PMID 17108034 DOI: 10.1128/JVI.01586-06  1
2007 Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT. Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53. Blood. 109: 2589-96. PMID 17105820 DOI: 10.1182/blood-2006-02-004234  1
2006 Nolan GP. Deeper insights into hematological oncology disorders via single-cell phospho-signaling analysis. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 123-7, 509. PMID 17124050 DOI: 10.1182/asheducation-2006.1.123  1
2006 He XS, Ji X, Hale MB, Cheung R, Ahmed A, Guo Y, Nolan GP, Pfeffer LM, Wright TL, Risch N, Tibshirani R, Greenberg HB. Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race. Hepatology (Baltimore, Md.). 44: 352-9. PMID 16871572 DOI: 10.1002/hep.21267  1
2006 Marks KM, Nolan GP. Chemical labeling strategies for cell biology. Nature Methods. 3: 591-6. PMID 16862131 DOI: 10.1038/nmeth906  1
2006 Irish JM, Czerwinski DK, Nolan GP, Levy R. Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry. Journal of Immunology (Baltimore, Md. : 1950). 177: 1581-9. PMID 16849466  1
2006 Irish JM, Czerwinski DK, Nolan GP, Levy R. Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells. Blood. 108: 3135-42. PMID 16835385 DOI: 10.1182/blood-2006-02-003921  1
2006 Hale MB, Nolan GP. Phospho-specific flow cytometry: intersection of immunology and biochemistry at the single-cell level. Current Opinion in Molecular Therapeutics. 8: 215-24. PMID 16774041  1
2006 Krutzik PO, Nolan GP. Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling. Nature Methods. 3: 361-8. PMID 16628206 DOI: 10.1038/nmeth872  1
2006 Perez OD, Nolan GP. Phospho-proteomic immune analysis by flow cytometry: From mechanism to translational medicine at the single-cell level Immunological Reviews. 210: 208-228. PMID 16623773 DOI: 10.1111/j.0105-2896.2006.00364.x  1
2006 Wehrman TS, von Degenfeld G, Krutzik PO, Nolan GP, Blau HM. Luminescent imaging of beta-galactosidase activity in living subjects using sequential reporter-enzyme luminescence. Nature Methods. 3: 295-301. PMID 16554835 DOI: 10.1038/nmeth868  1
2006 Irish JM, Kotecha N, Nolan GP. Mapping normal and cancer cell signalling networks: towards single-cell proteomics. Nature Reviews. Cancer. 6: 146-55. PMID 16491074 DOI: 10.1038/nrc1804  1
2006 Danna EA, Nolan GP. Transcending the biomarker mindset: deciphering disease mechanisms at the single cell level. Current Opinion in Chemical Biology. 10: 20-7. PMID 16406766 DOI: 10.1016/j.cbpa.2005.12.021  1
2006 Nolan GP. Proteomics and genomics: The emergent properties of biomarkers in mechanism and medicine Current Opinion in Chemical Biology. 10: 1-3. DOI: 10.1016/j.cbpa.2006.01.015  1
2005 Clutter MR, Krutzik PO, Nolan GP. Phospho-specific flow cytometry in drug discovery. Drug Discovery Today. Technologies. 2: 295-302. PMID 24981951 DOI: 10.1016/j.ddtec.2005.08.010  1
2005 Perez OD, Mitchell D, Campos R, Gao GJ, Li L, Nolan GP. Multiparameter analysis of intracellular phosphoepitopes in immunophenotyped cell populations by flow cytometry. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 6.20. PMID 18770823  1
2005 Schaap A, Fortin JF, Sommer M, Zerboni L, Stamatis S, Ku CC, Nolan GP, Arvin AM. T-cell tropism and the role of ORF66 protein in pathogenesis of varicella-zoster virus infection. Journal of Virology. 79: 12921-33. PMID 16188994 DOI: 10.1128/JVI.79.20.12921-12933.2005  1
2005 Krutzik PO, Hale MB, Nolan GP. Characterization of the murine immunological signaling network with phosphospecific flow cytometry. Journal of Immunology (Baltimore, Md. : 1950). 175: 2366-73. PMID 16081807  1
2005 Krutzik PO, Clutter MR, Nolan GP. Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry. Journal of Immunology (Baltimore, Md. : 1950). 175: 2357-65. PMID 16081806  1
2005 Sachs K, Perez O, Pe'er D, Lauffenburger DA, Nolan GP. Causal protein-signaling networks derived from multiparameter single-cell data. Science (New York, N.Y.). 308: 523-9. PMID 15845847 DOI: 10.1126/science.1105809  1
2005 Nolan GP. Tadpoles by the tail. Nature Methods. 2: 11-2. PMID 15782163 DOI: 10.1038/nmeth0105-11  1
2005 Berquin IM, Pang B, Dziubinski ML, Scott LM, Chen YQ, Nolan GP, Ethier SP. Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells. Oncogene. 24: 3177-86. PMID 15735691 DOI: 10.1038/sj.onc.1208504  1
2005 Stitz J, Krutzik PO, Nolan GP. Screening of retroviral cDNA libraries for factors involved in protein phosphorylation in signaling cascades. Nucleic Acids Research. 33: e39. PMID 15731332 DOI: 10.1093/nar/gni039  1
2005 Wolkowicz R, Nolan GP. Gene therapy progress and prospects: Novel gene therapy approaches for AIDS Gene Therapy. 12: 467-476. PMID 15703764 DOI: 10.1038/  1
2005 Wolkowicz R, Jager GC, Nolan GP. A random peptide library fused to CCR5 for selection of mimetopes expressed on the mammalian cell surface via retroviral vectors. The Journal of Biological Chemistry. 280: 15195-201. PMID 15657029 DOI: 10.1074/jbc.M500254200  1
2004 Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud Ø, Gjertsen BT, Nolan GP. Single cell profiling of potentiated phospho-protein networks in cancer cells Cell. 118: 217-228. PMID 15260991 DOI: 10.1016/j.cell.2004.06.028  1
2004 Condiotti R, Curran MA, Nolan GP, Giladi H, Ketzinel-Gilad M, Gross E, Galun E. Prolonged liver-specific transgene expression by a non-primate lentiviral vector. Biochemical and Biophysical Research Communications. 320: 998-1006. PMID 15240147 DOI: 10.1016/j.bbrc.2004.06.044  1
2004 Marks KM, Braun PD, Nolan GP. A general approach for chemical labeling and rapid, spatially controlled protein inactivation. Proceedings of the National Academy of Sciences of the United States of America. 101: 9982-7. PMID 15218100 DOI: 10.1073/pnas.0401609101  1
2004 Marks KM, Rosinov M, Nolan GP. In vivo targeting of organic calcium sensors via genetically selected peptides. Chemistry & Biology. 11: 347-56. PMID 15123264 DOI: 10.1016/j.chembiol.2004.03.004  1
2004 Perez OD, Mitchell D, Jager GC, Nolan GP. LFA-1 signaling through p44/42 is coupled to perforin degranulation in CD56+CD8+ natural killer cells Blood. 104: 1083-1093. PMID 15113754 DOI: 10.1182/blood-2003-08-2652  1
2004 Krutzik PO, Irish JM, Nolan GP, Perez OD. Analysis of protein phosphorylation and cellular signaling events by flow cytometry: Techniques and clinical applications Clinical Immunology. 110: 206-221. PMID 15047199 DOI: 10.1016/j.clim.2003.11.009  1
2004 Perez OD, Krutzik PO, Nolan GP. Flow cytometric analysis of kinase signaling cascades. Methods in Molecular Biology (Clifton, N.J.). 263: 67-94. PMID 14976361  1
2004 Wolkowicz R, Nolan GP, Curran MA. Lentiviral vectors for the delivery of DNA into mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 246: 391-411. PMID 14970606  1
2004 Hale MB, Nolan GP, Wolkowicz R. Oligonucleotide-directed site-specific integration of high complexity libraries into ssDNA templates. Nucleic Acids Research. 32: e22. PMID 14752044 DOI: 10.1093/nar/gnh021  1
2004 Sachs K, Perez OD, Pe'er D, Nolan GP, Gifford DK, Jaakkola TS, Lauffenburger DA. Analysis of signaling pathways in human T-cells using Bayesian network modeling of single cell data Proceedings - 2004 Ieee Computational Systems Bioinformatics Conference, Csb 2004. 644.  1
2003 Tarner IH, Slavin AJ, McBride J, Levicnik A, Smith R, Nolan GP, Contag CH, Fathman CG. Treatment of autoimmune disease by adoptive cellular gene therapy. Annals of the New York Academy of Sciences. 998: 512-9. PMID 14592922 DOI: 10.1196/annals.1254.067  1
2003 Perez OD, Mitchell D, Jager GC, South S, Murriel C, McBride J, Herzenberg LA, Kinoshita S, Nolan GP. Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1 Nature Immunology. 4: 1083-1092. PMID 14528303 DOI: 10.1038/ni984  1
2003 Krutzik PO, Nolan GP. Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 55: 61-70. PMID 14505311 DOI: 10.1002/cyto.a.10072  1
2003 Smith R, Tarner IH, Hollenhorst M, Lin C, Levicnik AU, Fathman CG, Nolan GP. Localized expression of an anti-TNF single-chain antibody prevents development of collagen-induced arthritis. Gene Therapy. 10: 1248-57. PMID 12858190 DOI: 10.1038/  1
2003 Scappaticci FA, Nolan GP. Induction of anti-tumor immunity in mice using a syngeneic endothelial cell vaccine Anticancer Research. 23: 1165-1172. PMID 12820367  1
2003 Wolkowicz R, Nolan GP. Retroviral technology--applications for expressed peptide libraries. Frontiers in Bioscience : a Journal and Virtual Library. 8: d603-19. PMID 12700115  1
2002 Price MA, Case SS, Carbonaro DA, Yu XJ, Petersen D, Sabo KM, Curran MA, Engel BC, Margarian H, Abkowitz JL, Nolan GP, Kohn DB, Crooks GM. Expression from second-generation feline immunodeficiency virus vectors is impaired in human hematopoietic cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 645-52. PMID 12409263 DOI: 10.1016/S1525-0016(02)90725-2  1
2002 Curran MA, Ochoa MS, Molano RD, Pileggi A, Inverardi L, Kenyon NS, Nolan GP, Ricordi C, Fenjves ES. Efficient transduction of pancreatic islets by feline immunodeficiency virus vectors1. Transplantation. 74: 299-306. PMID 12177606  1
2002 Fletcher BS, Dragstedt C, Notterpek L, Nolan GP. Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression. Leukemia. 16: 1507-18. PMID 12145692 DOI: 10.1038/sj.leu.2402557  1
2002 Fortin JF, Nolan GP. Recognizing a something when your library sees it. Chemistry & Biology. 9: 670-2. PMID 12079777 DOI: 10.1016/S1074-5521(02)00159-X  1
2002 Curran MA, Nolan GP. Recombinant feline immunodeficiency virus vectors. Preparation and use. Methods in Molecular Medicine. 69: 335-50. PMID 11987787  1
2002 Curran MA, Nolan GP. Nonprimate lentiviral vectors. Current Topics in Microbiology and Immunology. 261: 75-105. PMID 11892254  1
2002 Perez OD, Nolan GP, Magda D, Miller RA, Herzenberg LA. Motexafin gadolinium (Gd-Tex) selectively induces apoptosis in HIV-1 infected CD4+ T helper cells Proceedings of the National Academy of Sciences of the United States of America. 99: 2270-2274. PMID 11854523 DOI: 10.1073/pnas.261711499  1
2002 Perez OD, Kinoshita S, Hitoshi Y, Payan DG, Kitamura T, Nolan GP, Lorens JB. Activation of the PKB/AKT pathway by ICAM-2 Immunity. 16: 51-65. PMID 11825565 DOI: 10.1016/S1074-7613(02)00266-2  1
2002 Perez OD, Nolan GP. Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry Nature Biotechnology. 20: 155-162. PMID 11821861 DOI: 10.1038/nbt0202-155  1
2001 Swift S, Lorens J, Achacoso P, Nolan GP. Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 10.17C. PMID 18432682  1
2001 Scappaticci FA, Contreras A, Smith R, Bonhoure L, Lum B, Cao Y, Engleman EG, Nolan GP. Statin-AE: A novel angiostatin-endostatin fusion protein with enhanced antiangiogenic and antitumor activity Angiogenesis. 4: 263-268. PMID 12197471 DOI: 10.1023/A:1016067717433  1
2001 Perez OD, Nolan GP. Resistance is futile: Assimilation of cellular machinery by HIV-1 Immunity. 15: 687-690. PMID 11728331 DOI: 10.1016/S1074-7613(01)00238-2  1
2001 Berquin IM, Dziubinski ML, Nolan GP, Ethier SP. A functional screen for genes inducing epidermal growth factor autonomy of human mammary epithelial cells confirms the role of amphiregulin Oncogene. 20: 4019-4028. PMID 11494130 DOI: 10.1038/sj.onc.1204537  1
2001 Staal FJT, Meeldijk J, Moerer P, Jay P, Van De Weerdt BCM, Vainio S, Nolan GP, Clevers H. Strain-specific TCR repertoire selection of IL-4-producing Thy-1dull γδ thymocytes European Journal of Immunology. 31: 205-214. PMID 11265636 DOI: 10.1002/1521-4141(200101)31:1<205::AID-IMMU205>3.0.CO;2-8  1
2001 Scappaticci FA, Smith R, Pathak A, Schloss D, Lum B, Cao Y, Johnson F, Engleman EG, Nolan GP. Combination angiostatin and endostatin gene transfer induces synergistic antiangiogenic activity in vitro and antitumor efficacy in leukemia and solid tumors in mice Molecular Therapy. 3: 186-196. PMID 11237675 DOI: 10.1006/mthe.2000.0243  1
2001 Orentas RJ, Roskopf SJ, Nolan GP, Nishimura MI. Retroviral transduction of a T cell receptor specific for an Epstein-Barr virus-encoded peptide Clinical Immunology. 98: 220-228. PMID 11161978 DOI: 10.1006/clim.2000.4977  1
2001 Xu X, Leo C, Jang Y, Chan E, Padilla D, Huang BCB, Lin T, Gururaja T, Hitoshi Y, Lorens JB, Anderson DC, Sikic B, Luo Y, Payan DG, Nolan GP. Dominant effector genetics in mammalian cells Nature Genetics. 27: 23-29. PMID 11137994 DOI: 10.1038/83717  1
2000 Smith R, Nolan GP. Retroviral and lentiviral gene therapy for autoimmune disease Current Directions in Autoimmunity. 2: 167-188. PMID 11791455  1
2000 Rabizadeh S, Ye X, Sperandio S, Wang JJL, Ellerby HM, Ellerby LM, Giza C, Andrusiak RL, Frankowski H, Yaron Y, Moayeri NN, Rovelli G, Evans CJ, Butcher LL, Nolan GP, et al. Neurotrophin dependence domain: A domain required for the mediation of apoptosis by the p75 neurotrophin receptor Journal of Molecular Neuroscience. 15: 215-229. PMID 11303785 DOI: 10.1385/JMN:15:3:215  1
2000 Lorens JB, Bennett MK, Pearsall DM, Throndset WR, Rossi AB, Armstrong RJ, Fox BP, Chan EH, Luo Y, Masuda E, Ferrick DA, Anderson DC, Payan DG, Nolan GP. Retroviral delivery of peptide modulators of cellular functions. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 438-47. PMID 10933965 DOI: 10.1006/mthe.2000.0063  1
2000 Curran MA, Kaiser SM, Achacoso PL, Nolan GP. Efficient transduction of nondividing cells by optimized feline immunodeficiency virus vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 31-8. PMID 10933909 DOI: 10.1006/mthe.1999.0007  1
2000 Costa GL, Benson JM, Seroogy CM, Achacoso P, Fathman CG, Nolan GP. Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 164: 3581-90. PMID 10725713  1
1999 Foo SY, Nolan GP. NF-κB to the rescue: RELs, apoptosis and cellular transformation Trends in Genetics. 15: 229-235. PMID 10354583 DOI: 10.1016/S0168-9525(99)01719-9  1
1999 Yu PW, Huang BC, Shen M, Quast J, Chan E, Xu X, Nolan GP, Payan DG, Luo Y. Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB. Current Biology : Cb. 9: 539-42. PMID 10339433 DOI: 10.1016/S0960-9822(99)80239-5  1
1999 Vaziri H, Squire JA, Pandita TK, Bradley G, Kuba RM, Zhang H, Gulyas S, Hill RP, Nolan GP, Benchimol S. Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts Molecular and Cellular Biology. 19: 2373-2379. PMID 10022923  1
1999 Yang S, Delgado R, King SR, Woffendin C, Barker CS, Yang ZY, Xu L, Nolan GP, Nabel GJ. Generation of retroviral vector for clinical studies using transient transfection Human Gene Therapy. 10: 123-132. PMID 10022537 DOI: 10.1089/10430349950019255  1
1999 Park ST, Nolan GP, Sun XH. Growth inhibition and apoptosis due to restoration of E2A activity in T cell acute lymphoblastic leukemia cells Journal of Experimental Medicine. 189: 501-508. PMID 9927512 DOI: 10.1084/jem.189.3.501  1
1999 Dal Canto RA, Shaw MK, Nolan GP, Steinman L, Fathman CG. Local delivery of TNF by retrovirus-transduced T lymphocytes exacerbates experimental autoimmune encephalomyelitis. Clinical Immunology (Orlando, Fla.). 90: 10-4. PMID 9884347 DOI: 10.1006/clim.1998.4653  1
1999 Lorincz MC, Parente MK, Roederer M, Nolan GP, Diwu Z, Martin DIK, Herzenberg LA, Wolfe JH. Single cell analysis and selection of living retrovirus vector-corrected mucopolysaccharidosis VII cells using a fluorescence-activated cell sorting- based assay for mammalian β-glucuronidase enzymatic activity Journal of Biological Chemistry. 274: 657-665. PMID 9872999 DOI: 10.1074/jbc.274.2.657  1
1998 Rozinov MN, Nolan GP. Evolution of peptides that modulate the spectral qualities of bound, small-molecule fluorophores Chemistry and Biology. 5: 713-728. PMID 9862799  1
1998 Kinoshita S, Chen BK, Kaneshima H, Nolan GP. Host control of HIV-1 parasitism in T cells by the nuclear factor of activated T cells Cell. 95: 595-604. PMID 9845362  1
1998 Nolan GP, Shatzman AR. Expression vectors and delivery systems Current Opinion in Biotechnology. 9: 447-450. PMID 9821270 DOI: 10.1016/S0958-1669(98)80027-X  1
1998 Hitoshi Y, Lorens J, Kitada SI, Fisher J, LaBarge M, Ring HZ, Francke U, Reed JC, Kinoshita S, Nolan GP. Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells. Immunity. 8: 461-71. PMID 9586636 DOI: 10.1016/S1074-7613(00)80551-8  1
1998 Nolan GP. Transcription and the broken heart Nature. 392: 129-130. PMID 9515954 DOI: 10.1038/32290  1
1998 Grignani F, Kinsella T, Mencarelli A, Valtieri M, Riganelli D, Lanfrancone L, Peschle C, Nolan GP, Pelicci PG. High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein Cancer Research. 58: 14-19. PMID 9426049  1
1997 Kim DT, Mitchell DJ, Brockstedt DG, Fong L, Nolan GP, Fathman CG, Engleman EG, Rothbard JB. Introduction of soluble proteins into the MHC class I pathway by conjugation to an HIV tat peptide. Journal of Immunology (Baltimore, Md. : 1950). 159: 1666-8. PMID 9257826  1
1997 Shaw MK, Lorens JB, Dhawan A, DalCanto R, Tse HY, Tran AB, Bonpane C, Eswaran SL, Brocke S, Sarvetnick N, Steinman L, Nolan GP, Fathman CG. Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 185: 1711-4. PMID 9151908 DOI: 10.1084/jem.185.9.1711  1
1997 Kinoshita S, Su L, Amano M, Timmerman LA, Kaneshima H, Nolan GP. The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells Immunity. 6: 235-244. PMID 9075924 DOI: 10.1016/S1074-7613(00)80326-X  1
1996 Choate KA, Kinsella TM, Williams ML, Nolan GP, Khavari PA. Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes. Human Gene Therapy. 7: 2247-53. PMID 8953315 DOI: 10.1089/hum.1996.7.18-2247  1
1996 Montano MA, Kripke K, Norina CD, Achacoso P, Herzenberg LA, Roy AL, Nolan GP. NF-κB homodimer binding within the HIV-1 initiator region and interactions with TFII-I Proceedings of the National Academy of Sciences of the United States of America. 93: 12376-12381. PMID 8901589 DOI: 10.1073/pnas.93.22.12376  1
1996 Lorincz M, Roederer M, Diwu Z, Herzenberg LA, Nolan GP. Enzyme-generated intracellular fluorescence for single-cell resporter gene analysis utilizing Escherichia coli β-glucuronidase Cytometry. 24: 321-329. PMID 8866216 DOI: 10.1002/(SICI)1097-0320(19960801)24:4<321::AID-CYTO3>3.3.CO;2-3  1
1996 Kinsella TM, Nolan GP. Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. Human Gene Therapy. 7: 1405-13. PMID 8844199 DOI: 10.1089/hum.1996.7.12-1405  1
1996 Anderson MT, Tjioe IM, Lorincz MC, Parks DR, Herzenberg LA, Nolan GP. Simultaneous fluorescence-activated cell sorter analysis of two distinct transcriptional elements within a single cell using engineered green fluorescent proteins Proceedings of the National Academy of Sciences of the United States of America. 93: 8508-8511. PMID 8710900 DOI: 10.1073/pnas.93.16.8508  1
1996 Onishi M, Mui ALF, Morikawa Y, Cho L, Kinoshita S, Nolan GP, Gorman DM, Miyajima A, Kitamura T. Identification of an oncogenic form of the thrombopoietin receptor MPL using retrovirus-mediated gene transfer Blood. 88: 1399-1406. PMID 8695859  1
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