Arturo Zychlinsky - Publications

New York University, New York, NY, United States 
Microbiology Biology

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jhelum H, Čerina D, Harbort CJ, Lindner A, Hanitsch LG, Leistner R, Schröder JT, von Bernuth H, Stegemann MS, Schürmann M, Zychlinsky A, Krüger R, Marsman G. Panton-Valentine leukocidin-induced neutrophil extracellular traps lack antimicrobial activity and are readily induced in patients with recurrent PVL+-Staphylococcus aureus infections. Journal of Leukocyte Biology. PMID 37943843 DOI: 10.1093/jleuko/qiad137  0.34
2021 Burn GL, Foti A, Marsman G, Patel DF, Zychlinsky A. The Neutrophil. Immunity. 54: 1377-1391. PMID 34260886 DOI: 10.1016/j.immuni.2021.06.006  0.349
2021 Burn GL, Foti A, Marsman G, Patel DF, Zychlinsky A. The Neutrophil. Immunity. 54: 1377-1391. PMID 34260886 DOI: 10.1016/j.immuni.2021.06.006  0.349
2021 Apel F, Andreeva L, Knackstedt LS, Streeck R, Frese CK, Goosmann C, Hopfner KP, Zychlinsky A. The cytosolic DNA sensor cGAS recognizes neutrophil extracellular traps. Science Signaling. 14. PMID 33688080 DOI: 10.1126/scisignal.aax7942  0.352
2019 Knackstedt SL, Georgiadou A, Apel F, Abu-Abed U, Moxon CA, Cunnington AJ, Raupach B, Cunningham D, Langhorne J, Krüger R, Barrera V, Harding SP, Berg A, Patel S, Otterdal K, ... ... Zychlinsky A, et al. Neutrophil extracellular traps drive inflammatory pathogenesis in malaria. Science Immunology. 4. PMID 31628160 DOI: 10.1126/Sciimmunol.Aaw0336  0.361
2018 Sollberger G, Choidas A, Burn GL, Habenberger P, Di Lucrezia R, Kordes S, Menninger S, Eickhoff J, Nussbaumer P, Klebl B, Krüger R, Herzig A, Zychlinsky A. Gasdermin D plays a vital role in the generation of neutrophil extracellular traps. Science Immunology. 3. PMID 30143555 DOI: 10.1126/sciimmunol.aar6689  0.326
2018 Sollberger G, Tilley DO, Zychlinsky A. Neutrophil Extracellular Traps: The Biology of Chromatin Externalization. Developmental Cell. 44: 542-553. PMID 29533770 DOI: 10.1016/j.devcel.2018.01.019  0.35
2018 Virreira Winter S, Zychlinsky A. The bacterial pigment pyocyanin inhibits the NLRP3 inflammasome through intracellular reactive oxygen and nitrogen species. The Journal of Biological Chemistry. PMID 29414783 DOI: 10.1074/jbc.RA117.001105  0.332
2018 Deigendesch N, Zychlinsky A, Meissner F. Copper Regulates the Canonical NLRP3 Inflammasome. Journal of Immunology (Baltimore, Md. : 1950). PMID 29358279 DOI: 10.4049/jimmunol.1700712  0.344
2016 Sollberger G, Amulic B, Zychlinsky A. Neutrophil Extracellular Trap Formation Is Independent of De Novo Gene Expression. Plos One. 11: e0157454. PMID 27310721 DOI: 10.1371/Journal.Pone.0157454  0.321
2015 Stephenson HN, Herzig A, Zychlinsky A. Beyond the grave: When is cell death critical for immunity to infection? Current Opinion in Immunology. 38: 59-66. PMID 26682763 DOI: 10.1016/j.coi.2015.11.004  0.403
2015 Xu D, Olson J, Cole JN, van Wijk XM, Brinkmann V, Zychlinsky A, Nizet V, Esko JD, Chang YC. Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity. Infection and Immunity. 83: 3648-56. PMID 26150541 DOI: 10.1128/Iai.00545-15  0.312
2014 Bardoel BW, Kenny EF, Sollberger G, Zychlinsky A. The balancing act of neutrophils. Cell Host & Microbe. 15: 526-36. PMID 24832448 DOI: 10.1016/j.chom.2014.04.011  0.325
2014 Brotcke Zumsteg A, Goosmann C, Brinkmann V, Morona R, Zychlinsky A. IcsA is a Shigella flexneri adhesin regulated by the type III secretion system and required for pathogenesis. Cell Host & Microbe. 15: 435-45. PMID 24721572 DOI: 10.1016/j.chom.2014.03.001  0.319
2012 Senerovic L, Tsunoda SP, Goosmann C, Brinkmann V, Zychlinsky A, Meissner F, Kolbe M. Spontaneous formation of IpaB ion channels in host cell membranes reveals how Shigella induces pyroptosis in macrophages. Cell Death & Disease. 3: e384. PMID 22951981 DOI: 10.1038/cddis.2012.124  0.37
2010 Eilers B, Mayer-Scholl A, Walker T, Tang C, Weinrauch Y, Zychlinsky A. Neutrophil antimicrobial proteins enhance Shigella flexneri adhesion and invasion. Cellular Microbiology. 12: 1134-43. PMID 20331641 DOI: 10.1111/J.1462-5822.2010.01459.X  0.356
2010 Brinkmann V, Laube B, Abu Abed U, Goosmann C, Zychlinsky A. Neutrophil extracellular traps: how to generate and visualize them. Journal of Visualized Experiments : Jove. PMID 20182410 DOI: 10.3791/1724  0.346
2009 Ermert D, Urban CF, Laube B, Goosmann C, Zychlinsky A, Brinkmann V. Mouse neutrophil extracellular traps in microbial infections. Journal of Innate Immunity. 1: 181-93. PMID 20375576 DOI: 10.1159/000205281  0.347
2009 Papayannopoulos V, Zychlinsky A. NETs: a new strategy for using old weapons. Trends in Immunology. 30: 513-21. PMID 19699684 DOI: 10.1016/J.It.2009.07.011  0.328
2009 Ermert D, Zychlinsky A, Urban C. Fungal and bacterial killing by neutrophils. Methods in Molecular Biology (Clifton, N.J.). 470: 293-312. PMID 19089391 DOI: 10.1007/978-1-59745-204-5_21  0.361
2008 Meissner F, Molawi K, Zychlinsky A. Superoxide dismutase 1 regulates caspase-1 and endotoxic shock. Nature Immunology. 9: 866-72. PMID 18604212 DOI: 10.1038/ni.1633  0.447
2007 de Diego JL, Gerold G, Zychlinsky A. Sensing, presenting, and regulating PAMPs Ernst Schering Foundation Symposium Proceedings. 83-95. PMID 18510100  0.322
2007 Paetzold S, Lourido S, Raupach B, Zychlinsky A. Shigella flexneri phagosomal escape is independent of invasion. Infection and Immunity. 75: 4826-30. PMID 17664266 DOI: 10.1128/Iai.00454-07  0.32
2007 Gerold G, Zychlinsky A, de Diego JL. What is the role of Toll-like receptors in bacterial infections? Seminars in Immunology. 19: 41-7. PMID 17280841 DOI: 10.1016/j.smim.2006.12.003  0.338
2007 Fuchs TA, Abed U, Goosmann C, Hurwitz R, Schulze I, Wahn V, Weinrauch Y, Brinkmann V, Zychlinsky A. Novel cell death program leads to neutrophil extracellular traps. The Journal of Cell Biology. 176: 231-41. PMID 17210947 DOI: 10.1083/jcb.200606027  0.329
2006 Urban CF, Lourido S, Zychlinsky A. How do microbes evade neutrophil killing? Cellular Microbiology. 8: 1687-96. PMID 16939535 DOI: 10.1111/J.1462-5822.2006.00792.X  0.37
2006 Raupach B, Peuschel SK, Monack DM, Zychlinsky A. Caspase-1-mediated activation of interleukin-1beta (IL-1beta) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection. Infection and Immunity. 74: 4922-6. PMID 16861683 DOI: 10.1128/Iai.00417-06  0.555
2006 Ingersoll MA, Zychlinsky A. ShiA abrogates the innate T-cell response to Shigella flexneri infection. Infection and Immunity. 74: 2317-27. PMID 16552062 DOI: 10.1128/Iai.74.4.2317-2327.2006  0.67
2006 Urban CF, Reichard U, Brinkmann V, Zychlinsky A. Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms. Cellular Microbiology. 8: 668-76. PMID 16548892 DOI: 10.1111/j.1462-5822.2005.00659.x  0.351
2005 Weiss DS, Takeda K, Akira S, Zychlinsky A, Moreno E. MyD88, but not toll-like receptors 4 and 2, is required for efficient clearance of Brucella abortus. Infection and Immunity. 73: 5137-43. PMID 16041030 DOI: 10.1128/IAI.73.8.5137-5143.2005  0.567
2004 Mayer-Scholl A, Averhoff P, Zychlinsky A. How do neutrophils and pathogens interact? Current Opinion in Microbiology. 7: 62-6. PMID 15036142 DOI: 10.1016/j.mib.2003.12.004  0.31
2004 Weiss DS, Raupach B, Takeda K, Akira S, Zychlinsky A. Toll-like receptors are temporally involved in host defense. Journal of Immunology (Baltimore, Md. : 1950). 172: 4463-9. PMID 15034062  0.559
2004 Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, Weinrauch Y, Zychlinsky A. Neutrophil extracellular traps kill bacteria. Science (New York, N.Y.). 303: 1532-5. PMID 15001782 DOI: 10.1126/science.1092385  0.512
2003 Ingersoll MA, Moss JE, Weinrauch Y, Fisher PE, Groisman EA, Zychlinsky A. The ShiA protein encoded by the Shigella flexneri SHI-2 pathogenicity island attenuates inflammation. Cellular Microbiology. 5: 797-807. PMID 14531895 DOI: 10.1046/J.1462-5822.2003.00320.X  0.774
2003 Järveläinen HA, Galmiche A, Zychlinsky A. Caspase-1 activation by Salmonella. Trends in Cell Biology. 13: 204-9. PMID 12667758 DOI: 10.1016/S0962-8924(03)00032-1  0.475
2002 Weinrauch Y, Drujan D, Shapiro SD, Weiss J, Zychlinsky A. Neutrophil elastase targets virulence factors of enterobacteria. Nature. 417: 91-4. PMID 12018205 DOI: 10.1038/417091A  0.373
2002 Ingersoll M, Groisman EA, Zychlinsky A. Pathogenicity islands of Shigella Current Topics in Microbiology and Immunology. 264: 49-65. PMID 12014181 DOI: 10.1007/978-3-642-56031-6_4  0.622
2002 Raqib R, Ekberg C, Sharkar P, Bardhan PK, Zychlinsky A, Sansonetti PJ, Andersson J. Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2. Infection and Immunity. 70: 3199-207. PMID 12011015 DOI: 10.1128/Iai.70.6.3199-3207.2002  0.37
2002 Weiss DS, Zychlinsky A. 24 Methods for studying bacteria-induced host cell death Methods in Microbiology. 31: 439-460.  0.388
2001 Aliprantis AO, Weiss DS, Zychlinsky A. Toll-like receptor-2 transduces signals for NF-kappa B activation, apoptosis and reactive oxygen species production. Journal of Endotoxin Research. 7: 287-91. PMID 11717583 DOI: 10.1179/096805101101532864  0.691
2001 Aliprantis AO, Weiss DS, Radolf JD, Zychlinsky A. Release of Toll-like receptor-2-activating bacterial lipoproteins in Shigella flexneri culture supernatants. Infection and Immunity. 69: 6248-55. PMID 11553567 DOI: 10.1128/Iai.69.10.6248-6255.2001  0.743
2001 Guichon A, Hersh D, Smith MR, Zychlinsky A. Structure-function analysis of the Shigella virulence factor IpaB Journal of Bacteriology. 183: 1269-1276. PMID 11157939 DOI: 10.1128/Jb.183.4.1269-1276.2001  0.795
2001 Aliprantis AO, Weiss DS, Zychlinsky A. Toll-like receptor-2 transduces signals for NF-κB activation, apoptosis and reactive oxygen species production Journal of Endotoxin Research. 7: 287-291. DOI: 10.1177/09680519010070041101  0.712
2000 Moss JE, Fisher PE, Vick B, Groisman EA, Zychlinsky A. The regulatory protein PhoP controls susceptibility to the host inflammatory response in Shigella flexneri. Cellular Microbiology. 2: 443-52. PMID 11207599 DOI: 10.1046/J.1462-5822.2000.00065.X  0.738
2000 Navarre WW, Zychlinsky A. Pathogen-induced apoptosis of macrophages: A common end for different pathogenic strategies Cellular Microbiology. 2: 265-273. PMID 11207583 DOI: 10.1046/J.1462-5822.2000.00056.X  0.778
2000 Hilbi H, Puro RJ, Zychlinsky A. Tripeptidyl peptidase II promotes maturation of caspase-1 in Shigella flexneri-induced macrophage apoptosis Infection and Immunity. 68: 5502-5508. PMID 10992446 DOI: 10.1128/Iai.68.10.5502-5508.2000  0.509
2000 Monack DM, Hersh D, Ghori N, Bouley D, Zychlinsky A, Falkow S. Salmonella exploits caspase-1 to colonize Peyer's patches in a murine typhoid model. The Journal of Experimental Medicine. 192: 249-58. PMID 10899911 DOI: 10.1084/Jem.192.2.249  0.765
2000 Aliprantis AO, Yang RB, Weiss DS, Godowski P, Zychlinsky A. The apoptotic signaling pathway activated by Toll-like receptor-2. The Embo Journal. 19: 3325-36. PMID 10880445 DOI: 10.1093/Emboj/19.13.3325  0.777
2000 Sansonetti PJ, Phalipon A, Arondel J, Thirumalai K, Banerjee S, Akira S, Takeda K, Zychlinsky A. Caspase-1 activation of IL-1β and IL-18 are essential for Shigella flexneri-induced inflammation Immunity. 12: 581-590. PMID 10843390 DOI: 10.1016/S1074-7613(00)80209-5  0.356
2000 Aliprantis AO, Weiss D, Zychlinsky A. Lipoproteins and recognition by toll-like receptors Biochemical Society Transactions. 28: A114-A114. DOI: 10.1042/Bst028A114A  0.666
1999 Weinrauch Y, Zychlinsky A. The induction of apoptosis by bacterial pathogens Annual Review of Microbiology. 53: 155-187. PMID 10547689 DOI: 10.1146/annurev.micro.53.1.155  0.485
1999 Arondel J, Singer M, Matsukawa A, Zychlinsky A, Sansonetti PJ. Increased interleukin-1 (IL-1) and imbalance between IL-1 and IL-1 receptor antagonist during acute inflammation in experimental shigellosis Infection and Immunity. 67: 6056-6066. PMID 10531267 DOI: 10.1128/Iai.67.11.6056-6066.1999  0.302
1999 Aliprantis AO, Yang RB, Mark MR, Suggett S, Devaux B, Radolf JD, Klimpel GR, Godowski P, Zychlinsky A. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science (New York, N.Y.). 285: 736-9. PMID 10426996 DOI: 10.1126/Science.285.5428.736  0.767
1999 Moss JE, Cardozo TJ, Zychlinsky A, Groisman EA. The selC-associated SHI-2 pathogenicity island of Shigella flexneri. Molecular Microbiology. 33: 74-83. PMID 10411725 DOI: 10.1046/J.1365-2958.1999.01449.X  0.685
1999 Moss JE, Aliprantis AO, Zychlinsky A. The regulation of apoptosis by microbial pathogens. International Review of Cytology. 187: 203-59. PMID 10212981 DOI: 10.1016/S0074-7696(08)62419-5  0.791
1999 Hersh D, Monack DM, Smith MR, Ghori N, Falkow S, Zychlinsky A. The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1. Proceedings of the National Academy of Sciences of the United States of America. 96: 2396-401. PMID 10051653 DOI: 10.1073/Pnas.96.5.2396  0.792
1999 Zychlinsky A, Sansonetti PJ. Shigella host cell invasion. significance in pathogenesis Advances in Cellular and Molecular Biology of Membranes and Organelles. 6: 181-200. DOI: 10.1016/S1874-5172(99)80012-1  0.365
1999 Sansonetti PJ, Zychlinsky A. Apoptose et pouvoir pathogène des bactéries Revue Francaise Des Laboratoires. 1999: 51-55. DOI: 10.1016/S0338-9898(99)80037-7  0.571
1998 Hersh D, Weiss J, Zychlinsky A. How bacteria initiate inflammation: Aspects of the emerging story Current Opinion in Microbiology. 1: 43-48. PMID 10066463 DOI: 10.1016/S1369-5274(98)80141-0  0.777
1998 Hilbi H, Moss JE, Hersh D, Chen Y, Arondel J, Banerjee S, Flavell RA, Yuan J, Sansonetti PJ, Zychlinsky A. Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB. The Journal of Biological Chemistry. 273: 32895-900. PMID 9830039 DOI: 10.1074/Jbc.273.49.32895  0.786
1998 Hilbi H, Zychlinsky A, Sansonetti PJ. Macrophage apoptosis in microbial infections. Parasitology. S79-87. PMID 9571693 DOI: 10.1017/S0031182097001790  0.593
1997 Hilbi H, Chen Y, Thirumalai K, Zychlinsky A. The interleukin 1β-converting enzyme, caspase 1, is activated during Shigella flexneri-induced apoptosis in human monocyte-derived macrophages Infection and Immunity. 65: 5165-5170. PMID 9393811 DOI: 10.1128/Iai.65.12.5165-5170.1997  0.512
1997 Zychlinsky A, Sansonetti P. Perspectives series: host/pathogen interactions. Apoptosis in bacterial pathogenesis The Journal of Clinical Investigation. 100: 493-495. PMID 9239394  0.371
1997 Guichon A, Zychlinsky A. Clinical isolates of Shigella species induce apoptosis in macrophages Journal of Infectious Diseases. 175: 470-473. PMID 9203676 DOI: 10.1093/Infdis/175.2.470  0.474
1997 Zychlinsky A, Sansonetti PJ. Apoptosis as a proinflammatory event: What can we learn from bacteria- induced cell death? Trends in Microbiology. 5: 201-204. PMID 9160509 DOI: 10.1016/S0966-842X(97)01044-5  0.574
1997 Thirumalai K, Kim KS, Zychlinsky A. IpaB, a Shigella flexneri invasin, colocalizes with interleukin-1β- converting enzyme in the cytoplasm of macrophages Infection and Immunity. 65: 787-793. PMID 9009343  0.329
1997 Hilbi H, Chen Y, Thirumalai K, Zychlinsky A. The interleukin 1beta-converting enzyme, caspase 1, is activated during Shigella flexneri-induced apoptosis in human monocyte-derived macrophages. Infection and Immunity. 65: 5165-5170. DOI: 10.1128/iai.65.12.5165-5170.1997  0.356
1997 Zychlinsky A, Sansonetti P. Apoptosis in bacterial pathogenesis Journal of Clinical Investigation. 100: S63-S65. DOI: 10.1042/Bst024591S  0.518
1996 Aliprantis AO, Diez-Roux G, Mulder LC, Zychlinsky A, Lang RA. Do macrophages kill through apoptosis? Immunology Today. 17: 573-6. PMID 8991289 DOI: 10.1016/S0167-5699(96)10071-2  0.718
1996 Guichon A, Zychlinsky A. Apoptosis as a trigger of inflammation in Shigella-induced cell death Biochemical Society Transactions. 24: 1051-1054. PMID 8968510 DOI: 10.1042/Bst0241051  0.497
1996 Zychlinsky A, Thirumalai K, Arondel J, Cantey JR, Aliprantis AO, Sansonetti PJ. In vivo apoptosis in Shigella flexneri infections. Infection and Immunity. 64: 5357-65. PMID 8945588 DOI: 10.1128/Iai.64.12.5357-5365.1996  0.71
1996 Chen Y, Smith MR, Thirumalai K, Zychlinsky A. A bacterial invasin induces macrophage apoptosis by binding directly to ICE Embo Journal. 15: 3853-3860. PMID 8670890 DOI: 10.1002/J.1460-2075.1996.Tb00759.X  0.489
1994 Zychlinsky A, Kenny B, Ménard R, Prévost MC, Holland IB, Sansonetti PJ. IpaB mediates macrophage apoptosis induced by Shigella flexneri Molecular Microbiology. 11: 619-627. PMID 8196540 DOI: 10.1111/J.1365-2958.1994.Tb00341.X  0.417
1994 Zychlinsky A, Perdomo JJ, Sansonetti PJ. Molecular and cellular mechanisms of tissue invasion by Shigella flexneri Annals of the New York Academy of Sciences. 730: 197-208. PMID 8080171 DOI: 10.1111/J.1749-6632.1994.Tb44249.X  0.361
1994 Chen Y, Zychlinsky A. Apoptosis induced by bacterial pathogens Microbial Pathogenesis. 17: 203-212. PMID 7715420 DOI: 10.1006/Mpat.1994.1066  0.544
1993 Khelef N, Zychlinsky A, Guiso N. Bordetella pertussis induces apoptosis in macrophages: Role of adenylate cyclase-hemolysin Infection and Immunity. 61: 4064-4071. PMID 8406793  0.471
1993 Zychlinsky A. Programmed cell death in infectious diseases Trends in Microbiology. 1: 114-117. PMID 8143119 DOI: 10.1016/0966-842X(93)90118-B  0.355
1992 Zychlinsky A, Prevost MC, Sansonetti PJ. Shigella flexneri induces apoptosis in infected macrophages Nature. 358: 167-169. PMID 1614548 DOI: 10.1038/358167A0  0.446
1991 Zychlinsky A, Zheng LM, Liu CC, Young JDE. Cytolytic lymphocytes induce both apoptosis and necrosis in target cells Journal of Immunology. 146: 393-400. PMID 1984450  0.332
1991 Zheng LM, Zychlinsky A, Liu CC, Ojcius DM, Young JDE. Extracellular APT as a trigger for apoptosis or programmed cell death Journal of Cell Biology. 112: 279-288. DOI: 10.1083/Jcb.112.2.279  0.3
1990 Zychlinsky A, Karim M, Nonacs R, Young JDE. A homogeneous population of lymphokine-activated killer (LAK) cells is incapable of killing virus-, bacteria-, or parasite-infected macrophages Cellular Immunology. 125: 261-267. PMID 2104576 DOI: 10.1016/0008-8749(90)90080-B  0.311
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