Vinayaka R. Prasad - Publications

Affiliations: 
Yeshiva University, New York, NY, United States 
Area:
Molecular Biology, Biochemistry, Microbiology Biology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ajasin DO, Rao VR, Wu X, Ramasamy S, Pujato M, Ruiz AP, Fiser A, Bresnick AR, Kalpana GV, Prasad VR. CCL2 mobilizes ALIX to facilitate Gag-p6 mediated HIV-1 virion release. Elife. 8. PMID 31172941 DOI: 10.7554/eLife.35546  0.4
2017 Prasad VR, Kalpana GV. FISHing Out the Hidden Enemy: Advances in Detecting and Measuring Latent HIV-Infected Cells. Mbio. 8. PMID 28928214 DOI: 10.1128/mBio.01433-17  0.4
2016 Rao VR, Eugenin EA, Prasad VR. Evaluating the Role of Viral Proteins in HIV-Mediated Neurotoxicity Using Primary Human Neuronal Cultures. Methods in Molecular Biology (Clifton, N.J.). 1354: 367-76. PMID 26714725 DOI: 10.1007/978-1-4939-3046-3_25  0.68
2016 Ruiz AP, Prasad VR. Measuring the Uptake and Transactivation Function of HIV-1 Tat Protein in a Trans-cellular Cocultivation Setup. Methods in Molecular Biology (Clifton, N.J.). 1354: 353-66. PMID 26714724 DOI: 10.1007/978-1-4939-3046-3_24  0.68
2015 Dara J, Dow A, Cromwell E, Sturdevant CB, Mallewa M, Swanstrom R, Van Rie A, Prasad VR. Multivariable analysis to determine if HIV-1 Tat dicysteine motif is associated with neurodevelopmental delay in HIV-infected children in Malawi. Behavioral and Brain Functions : Bbf. 11: 38. PMID 26678821 DOI: 10.1186/s12993-015-0083-7  0.68
2015 G Aralaguppe SP, Sharma S, Menon M, Prasad VR, Saravanan S, Murugavel KG, Solomon S, Ranga U. The evolving profile of the signature amino acid residues in HIV-1 subtype C Tat. Aids Research and Human Retroviruses. PMID 26678403 DOI: 10.1089/AID.2015.0208  0.68
2015 Duclair S, Gautam A, Ellington A, Prasad VR. High-affinity RNA Aptamers Against the HIV-1 Protease Inhibit Both In Vitro Protease Activity and Late Events of Viral Replication. Molecular Therapy. Nucleic Acids. 4: e228. PMID 25689224 DOI: 10.1038/mtna.2015.1  0.68
2014 Garforth SJ, Lwatula C, Prasad VR. The lysine 65 residue in HIV-1 reverse transcriptase function and in nucleoside analog drug resistance. Viruses. 6: 4080-94. PMID 25341667 DOI: 10.3390/v6104080  0.68
2014 Rao VR, Neogi U, Eugenin E, Prasad VR. The gp120 protein is a second determinant of decreased neurovirulence of Indian HIV-1C isolates compared to southern African HIV-1C isolates. Plos One. 9: e107074. PMID 25188269 DOI: 10.1371/journal.pone.0107074  0.68
2014 Neogi U, Rao SD, Bontell I, Verheyen J, Rao VR, Gore SC, Soni N, Shet A, Schülter E, Ekstrand ML, Wondwossen A, Kaiser R, Madhusudhan MS, Prasad VR, Sonnerborg A. Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure in Indian patients. Aids (London, England). 28: 2319-22. PMID 25102091 DOI: 10.1097/QAD.0000000000000419  0.68
2014 Prasad VR, Bukrinsky MI. New clues to understanding HIV nonprogressors: low cholesterol blocks HIV trans infection. Mbio. 5: e01396-14. PMID 24917601 DOI: 10.1128/mBio.01396-14  0.68
2014 Rao VR, Ruiz AP, Prasad VR. Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND). Aids Research and Therapy. 11: 13. PMID 24894206 DOI: 10.1186/1742-6405-11-13  0.68
2014 Hanna LE, Neogi U, Ranga U, Swaminathan S, Prasad VR. Phylogenetic characterization of six full-length HIV-1 subtype C molecular clones from three patients: identification of rare subtype C strains containing two NF-κB motifs in the long terminal repeat. Aids Research and Human Retroviruses. 30: 586-91. PMID 24387762 DOI: 10.1089/AID.2013.0275  0.68
2013 Mathew S, Nguyen M, Wu X, Pal A, Shah VB, Prasad VR, Aiken C, Kalpana GV. INI1/hSNF5-interaction defective HIV-1 IN mutants exhibit impaired particle morphology, reverse transcription and integration in vivo. Retrovirology. 10: 66. PMID 23799881 DOI: 10.1186/1742-4690-10-66  0.68
2013 Rao VR, Neogi U, Talboom JS, Padilla L, Rahman M, Fritz-French C, Gonzalez-Ramirez S, Verma A, Wood C, Ruprecht RM, Ranga U, Azim T, Joska J, Eugenin E, Shet A, ... ... Prasad VR, et al. Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence. Retrovirology. 10: 61. PMID 23758766 DOI: 10.1186/1742-4690-10-61  0.68
2012 Lwatula C, Garforth SJ, Prasad VR. Lys66 residue as a determinant of high mismatch extension and misinsertion rates of HIV-1 reverse transcriptase. The Febs Journal. 279: 4010-24. PMID 22925131 DOI: 10.1111/j.1742-4658.2012.08807.x  0.68
2012 Kim J, Wang L, Li Y, Becnel KD, Frey KM, Garforth SJ, Prasad VR, Schinazi RF, Liotta DC, Anderson KS. Pre-steady state kinetic analysis of cyclobutyl derivatives of 2′-deoxyadenosine 5′-triphosphate as inhibitors of HIV-1 reverse transcriptase Bioorganic and Medicinal Chemistry Letters. 22: 4064-4067. PMID 22595174 DOI: 10.1016/j.bmcl.2012.04.078  0.68
2011 Ramalingam D, Duclair S, Datta SA, Ellington A, Rein A, Prasad VR. RNA aptamers directed to human immunodeficiency virus type 1 Gag polyprotein bind to the matrix and nucleocapsid domains and inhibit virus production. Journal of Virology. 85: 305-14. PMID 20980522 DOI: 10.1128/JVI.02626-09  0.68
2010 Garforth SJ, Domaoal RA, Lwatula C, Landau MJ, Meyer AJ, Anderson KS, Prasad VR. K65R and K65A substitutions in HIV-1 reverse transcriptase enhance polymerase fidelity by decreasing both dNTP misinsertion and mispaired primer extension efficiencies. Journal of Molecular Biology. 401: 33-44. PMID 20538005 DOI: 10.1016/j.jmb.2010.06.001  0.68
2010 Drosopoulos WC, Prasad VR. The telomerase-specific T motif is a restrictive determinant of repetitive reverse transcription by human telomerase. Molecular and Cellular Biology. 30: 447-59. PMID 19917726 DOI: 10.1128/MCB.00853-09  0.68
2009 Rao VR, Eugenin EA, Berman JW, Prasad VR. Methods to study monocyte migration induced by HIV-infected cells. Methods in Molecular Biology (Clifton, N.J.). 485: 295-309. PMID 19020833 DOI: 10.1007/978-1-59745-170-3_20  0.68
2008 Rao VR, Sas AR, Eugenin EA, Siddappa NB, Bimonte-Nelson H, Berman JW, Ranga U, Tyor WR, Prasad VR. HIV-1 clade-specific differences in the induction of neuropathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10010-6. PMID 18829958 DOI: 10.1523/JNEUROSCI.2955-08.2008  0.68
2008 Garforth SJ, Parniak MA, Prasad VR. Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase. Plos One. 3: e2074. PMID 18446195 DOI: 10.1371/journal.pone.0002074  0.64
2008 Silverman AP, Garforth SJ, Prasad VR, Kool ET. Probing the active site steric flexibility of HIV-1 reverse transcriptase: different constraints for DNA- versus RNA-templated synthesis. Biochemistry. 47: 4800-7. PMID 18366188 DOI: 10.1021/bi702427y  0.68
2007 Braun SE, Shi X, Qiu G, Wong FE, Joshi PJ, Prasad VR, Johnson RP. Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter. Aids Research and Therapy. 4: 24. PMID 17941994 DOI: 10.1186/1742-6405-4-24  0.44
2007 Drosopoulos WC, Prasad VR. The active site residue Valine 867 in human telomerase reverse transcriptase influences nucleotide incorporation and fidelity. Nucleic Acids Research. 35: 1155-68. PMID 17264120 DOI: 10.1093/nar/gkm002  0.68
2007 Garforth SJ, Kim TW, Parniak MA, Kool ET, Prasad VR. Site-directed mutagenesis in the fingers subdomain of HIV-1 reverse transcriptase reveals a specific role for the beta3-beta4 hairpin loop in dNTP selection. Journal of Molecular Biology. 365: 38-49. PMID 17055529 DOI: 10.1016/j.jmb.2006.09.057  0.68
2006 Dash C, Fisher TS, Prasad VR, Le Grice SF. Examining interactions of HIV-1 reverse transcriptase with single-stranded template nucleotides by nucleoside analog interference. The Journal of Biological Chemistry. 281: 27873-81. PMID 16867979 DOI: 10.1074/jbc.M603970200  0.92
2006 Mandal D, Dash C, Le Grice SF, Prasad VR. Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function. Nucleic Acids Research. 34: 2853-63. PMID 16723431 DOI: 10.1093/nar/gkl360  0.32
2006 Garforth SJ, Wu YY, Prasad VR. Structural features of mouse telomerase RNA are responsible for the lower activity of mouse telomerase versus human telomerase. The Biochemical Journal. 397: 399-406. PMID 16669789 DOI: 10.1042/BJ20060456  0.64
2006 Curr K, Tripathi S, Lennerstrand J, Larder BA, Prasad VR. Influence of naturally occurring insertions in the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase on polymerase fidelity and mutation frequencies in vitro. The Journal of General Virology. 87: 419-28. PMID 16432030 DOI: 10.1099/vir.0.81458-0  0.4
2006 Hamburgh ME, Curr KA, Monaghan M, Rao VR, Tripathi S, Preston BD, Sarafianos S, Arnold E, Darden T, Prasad VR. Structural determinants of slippage-mediated mutations by human immunodeficiency virus type 1 reverse transcriptase. The Journal of Biological Chemistry. 281: 7421-8. PMID 16423828 DOI: 10.1074/jbc.M511380200  0.68
2005 Fisher TS, Joshi P, Prasad VR. HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors. Aids Research and Therapy. 2: 8. PMID 16207371 DOI: 10.1186/1742-6405-2-8  0.92
2005 Drosopoulos WC, Direnzo R, Prasad VR. Human telomerase RNA template sequence is a determinant of telomere repeat extension rate. The Journal of Biological Chemistry. 280: 32801-10. PMID 16061476 DOI: 10.1074/jbc.M506319200  0.68
2005 Joshi PJ, North TW, Prasad VR. Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 677-86. PMID 15851006 DOI: 10.1016/j.ymthe.2005.01.013  0.68
2004 Hehl EA, Joshi P, Kalpana GV, Prasad VR. Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins. Journal of Virology. 78: 5056-67. PMID 15113887 DOI: 10.1128/JVI.78.10.5056-5067.2004  0.68
2003 Joshi PJ, Fisher TS, Prasad VR. Anti-HIV inhibitors based on nucleic acids: emergence of aptamers as potent antivirals. Current Drug Targets. Infectious Disorders. 3: 383-400. PMID 14754437  0.92
2003 Fisher TS, Darden T, Prasad VR. Mutations proximal to the minor groove-binding track of human immunodeficiency virus type 1 reverse transcriptase differentially affect utilization of RNA versus DNA as template. Journal of Virology. 77: 5837-45. PMID 12719577 DOI: 10.1128/JVI.77.10.5837-5845.2003  0.68
2003 Fisher TS, Darden T, Prasad VR. Substitutions at Phe61 in the beta3-beta4 hairpin of HIV-1 reverse transcriptase reveal a role for the Fingers subdomain in strand displacement DNA synthesis. Journal of Molecular Biology. 325: 443-59. PMID 12498795 DOI: 10.1016/S0022-2836(02)01225-1  0.68
2002 Joshi P, Prasad VR. Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment). Journal of Virology. 76: 6545-57. PMID 12050367  0.48
2002 Fisher TS, Prasad VR. Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase. The Journal of Biological Chemistry. 277: 22345-52. PMID 11948182 DOI: 10.1074/jbc.M200282200  0.92
2002 Fisher TS, Joshi P, Prasad VR. Mutations that confer resistance to template-analog inhibitors of human immunodeficiency virus (HIV) type 1 reverse transcriptase lead to severe defects in HIV replication. Journal of Virology. 76: 4068-72. PMID 11907245  0.92
2000 Shah FS, Curr KA, Hamburgh ME, Parniak M, Mitsuya H, Arnez JG, Prasad VR. Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase. The Journal of Biological Chemistry. 275: 27037-44. PMID 10833521 DOI: 10.1074/jbc.M002881200  0.68
1998 Hamburgh ME, Drosopoulos WC, Prasad VR. The influence of 3TC-resistance mutations E89G and M184V in the human immunodeficiency virus reverse transcriptase on mispair extension efficiency. Nucleic Acids Research. 26: 4389-94. PMID 9742239 DOI: 10.1093/nar/26.19.4389  0.68
1996 Prasad VR, Drosopoulos WC, Hamburgh ME. Perspective: research highlights at the Albert Einstein College of Medicine Center for AIDS research. Approaches to control drug resistance in HIV: the role of increased polymerase fidelity. Aids Research and Human Retroviruses. 12: 959-63. PMID 8827210  0.68
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