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Brian Gebelein - Publications

Affiliations: 
Cincinnati Children's Hospital, Cincinnati, OH, United States 
Area:
Drosophila development
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54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Webb JA, Farrow E, Cain B, Yuan Z, Yarawsky AE, Schoch E, Gagliani EK, Herr AB, Gebelein B, Kovall RA. Cooperative Gsx2-DNA Binding Requires DNA Bending and a Novel Gsx2 Homeodomain Interface. Biorxiv : the Preprint Server For Biology. PMID 38106145 DOI: 10.1101/2023.12.08.570805  0.354
2023 Cain B, Webb J, Yuan Z, Cheung D, Lim HW, Kovall RA, Weirauch MT, Gebelein B. Prediction of cooperative homeodomain DNA binding sites from high-throughput-SELEX data. Nucleic Acids Research. PMID 37114997 DOI: 10.1093/nar/gkad318  0.374
2022 Salomone J, Farrow E, Gebelein B. Homeodomain complex formation and biomolecular condensates in Hox gene regulation. Seminars in Cell & Developmental Biology. PMID 36517343 DOI: 10.1016/j.semcdb.2022.11.016  0.484
2022 Gagliani EK, Gutzwiller LM, Kuang Y, Odaka Y, Hoffmeister P, Hauff S, Turkiewicz A, Harding-Theobald E, Dolph PJ, Borggrefe T, Oswald F, Gebelein B, Kovall RA. A Drosophila Su(H) model of Adams-Oliver Syndrome reveals cofactor titration as a mechanism underlying developmental defects. Plos Genetics. 18: e1010335. PMID 35951645 DOI: 10.1371/journal.pgen.1010335  0.327
2021 Cain B, Gebelein B. Mechanisms Underlying Hox-Mediated Transcriptional Outcomes. Frontiers in Cell and Developmental Biology. 9: 787339. PMID 34869389 DOI: 10.3389/fcell.2021.787339  0.426
2021 Kuang Y, Pyo A, Eafergan N, Cain B, Gutzwiller LM, Axelrod O, Gagliani EK, Weirauch MT, Kopan R, Kovall RA, Sprinzak D, Gebelein B. Enhancers with cooperative Notch binding sites are more resistant to regulation by the Hairless co-repressor. Plos Genetics. 17: e1009039. PMID 34559800 DOI: 10.1371/journal.pgen.1009039  0.384
2020 Salomone J, Qin S, Fufa TD, Cain B, Farrow E, Guan B, Hufnagel RB, Nakafuku M, Lim HW, Campbell K, Gebelein B. Conserved Gsx2/Ind homeodomain monomer versus homodimer DNA binding defines regulatory outcomes in flies and mice. Genes & Development. PMID 33334823 DOI: 10.1101/gad.343053.120  0.47
2020 Kobia FM, Preusse K, Dai Q, Weaver N, Hass MR, Chaturvedi P, Stein SJ, Pear WS, Yuan Z, Kovall RA, Kuang Y, Eafergen N, Sprinzak D, Gebelein B, Brunskill EW, et al. Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation. Plos Biology. 18: e3000850. PMID 33017398 DOI: 10.1371/journal.pbio.3000850  0.354
2020 Elliott KH, Chen X, Salomone J, Chaturvedi P, Schultz PA, Balchand SK, Servetas JD, Zuniga A, Zeller R, Gebelein B, Weirauch MT, Peterson KA, Brugmann SA. Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks. Elife. 9. PMID 33006313 DOI: 10.7554/eLife.56450  0.397
2020 Kuang Y, Golan O, Preusse K, Cain B, Christensen CJ, Salomone J, Campbell I, Okwubido-Williams FV, Hass MR, Yuan Z, Eafergan N, Moberg KH, Kovall RA, Kopan R, Sprinzak D, ... Gebelein B, et al. Enhancer architecture sensitizes cell-specific responses to gene dose via a bind and discard mechanism. Elife. 9. PMID 32297857 DOI: 10.7554/Elife.53659  0.485
2020 Roychoudhury K, Salomone J, Qin S, Cain B, Adam M, Potter SS, Nakafuku M, Gebelein B, Campbell K. Physical interactions between Gsx2 and Ascl1 balance progenitor expansion versus neurogenesis in the mouse lateral ganglionic eminence. Development (Cambridge, England). PMID 32122989 DOI: 10.1242/Dev.185348  0.488
2020 Kuang Y, Golan O, Preusse K, Cain B, Christensen CJ, Salomone J, Campbell I, Okwubido-Williams FV, Hass MR, Yuan Z, Eafergan N, Moberg KH, Kovall RA, Kopan R, Sprinzak D, ... Gebelein B, et al. Author response: Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism Elife. DOI: 10.7554/Elife.53659.Sa2  0.373
2019 Zhang X, McGrath PS, Salomone J, Rahal M, McCauley HA, Schweitzer J, Kovall R, Gebelein B, Wells JM. A Comprehensive Structure-Function Study of Neurogenin3 Disease-Causing Alleles during Human Pancreas and Intestinal Organoid Development. Developmental Cell. PMID 31178402 DOI: 10.1016/J.Devcel.2019.05.017  0.347
2018 Zandvakili A, Uhl JD, Campbell I, Salomone J, Song YC, Gebelein B. The cis-regulatory logic underlying abdominal Hox-mediated repression versus activation of regulatory elements in Drosophila. Developmental Biology. PMID 30468713 DOI: 10.1016/J.Ydbio.2018.11.006  0.526
2018 Zandvakili A, Campbell I, Gutzwiller LM, Weirauch MT, Gebelein B. Degenerate Pax2 and Senseless binding motifs improve detection of low-affinity sites required for enhancer specificity. Plos Genetics. 14: e1007289. PMID 29617378 DOI: 10.1371/Journal.Pgen.1007289  0.471
2017 Wang G, Gutzwiller L, Li-Kroeger D, Gebelein B. A Hox complex activates and potentiates the Epidermal Growth Factor signaling pathway to specify Drosophila oenocytes. Plos Genetics. 13: e1006910. PMID 28715417 DOI: 10.1371/Journal.Pgen.1006910  0.436
2016 Uhl JD, Zandvakili A, Gebelein B. A Hox Transcription Factor Collective Binds a Highly Conserved Distal-less cis-Regulatory Module to Generate Robust Transcriptional Outcomes. Plos Genetics. 12: e1005981. PMID 27058369 DOI: 10.1371/Journal.Pgen.1005981  0.585
2015 Gresser AL, Gutzwiller LM, Gauck MK, Hartenstein V, Cook TA, Gebelein B. Rhomboid Enhancer Activity Defines a Subset of Drosophila Neural Precursors Required for Proper Feeding, Growth and Viability. Plos One. 10: e0134915. PMID 26252385 DOI: 10.1371/Journal.Pone.0134915  0.367
2014 Velu CS, Chaubey A, Phelan JD, Horman SR, Wunderlich M, Guzman ML, Jegga AG, Zeleznik-Le NJ, Chen J, Mulloy JC, Cancelas JA, Jordan CT, Aronow BJ, Marcucci G, Bhat B, ... Gebelein B, et al. Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity. The Journal of Clinical Investigation. 124: 222-36. PMID 24334453 DOI: 10.1172/Jci66005  0.452
2014 Velu CS, Chaubey A, Phelan JD, Meyer S, Horman SR, Wunderlich M, Guzman ML, Jegga AG, Zeleznik-Le NJ, Chen J, Mulloy JC, Cancelas JA, Jordan CT, Aronow BJ, Marcucci G, ... ... Gebelein B, et al. Abstract 979: microRNA-mediated leukemia-initiating cell activity Cancer Research. 74: 979-979. DOI: 10.1158/1538-7445.Am2014-979  0.366
2013 Jukam D, Xie B, Rister J, Terrell D, Charlton-Perkins M, Pistillo D, Gebelein B, Desplan C, Cook T. Opposite feedbacks in the Hippo pathway for growth control and neural fate. Science (New York, N.Y.). 342: 1238016. PMID 23989952 DOI: 10.1126/Science.1238016  0.357
2012 Fujioka M, Gebelein B, Cofer ZC, Mann RS, Jaynes JB. Engrailed cooperates directly with Extradenticle and Homothorax on a distinct class of homeodomain binding sites to repress sloppy paired. Developmental Biology. 366: 382-92. PMID 22537495 DOI: 10.1016/J.Ydbio.2012.04.004  0.643
2012 Li-Kroeger D, Cook TA, Gebelein B. Integration of an abdominal Hox complex with Pax2 yields cell-specific EGF secretion from Drosophila sensory precursor cells. Development (Cambridge, England). 139: 1611-9. PMID 22438572 DOI: 10.1242/Dev.077842  0.488
2012 Burns KA, Gutzwiller LM, Tomoyasu Y, Gebelein B. Oenocyte development in the red flour beetle Tribolium castaneum. Development Genes and Evolution. 222: 77-88. PMID 22382810 DOI: 10.1007/S00427-012-0390-Z  0.395
2012 Terrell D, Xie B, Workman M, Mahato S, Zelhof A, Gebelein B, Cook T. OTX2 and CRX rescue overlapping and photoreceptor-specific functions in the Drosophila eye. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 215-28. PMID 22113834 DOI: 10.1002/Dvdy.22782  0.425
2011 Johnston RJ, Otake Y, Sood P, Vogt N, Behnia R, Vasiliauskas D, McDonald E, Xie B, Koenig S, Wolf R, Cook T, Gebelein B, Kussell E, Nakagoshi H, Desplan C. Interlocked feedforward loops control cell-type-specific Rhodopsin expression in the Drosophila eye. Cell. 145: 956-68. PMID 21663797 DOI: 10.1016/J.Cell.2011.05.003  0.434
2011 Charlton-Perkins M, Whitaker SL, Fei Y, Xie B, Li-Kroeger D, Gebelein B, Cook T. Prospero and Pax2 combinatorially control neural cell fate decisions by modulating Ras- and Notch-dependent signaling. Neural Development. 6: 20. PMID 21539742 DOI: 10.1186/1749-8104-6-20  0.346
2010 Gutzwiller LM, Witt LM, Gresser AL, Burns KA, Cook TA, Gebelein B. Proneural and abdominal Hox inputs synergize to promote sensory organ formation in the Drosophila abdomen. Developmental Biology. 348: 231-43. PMID 20875816 DOI: 10.1016/J.Ydbio.2010.09.014  0.462
2010 McDonald EC, Xie B, Workman M, Charlton-Perkins M, Terrell DA, Reischl J, Wimmer EA, Gebelein BA, Cook TA. Separable transcriptional regulatory domains within Otd control photoreceptor terminal differentiation events. Developmental Biology. 347: 122-32. PMID 20732315 DOI: 10.1016/J.Ydbio.2010.08.016  0.427
2010 Phelan JD, Shroyer NF, Cook T, Gebelein B, Grimes HL. Gfi1-cells and circuits: unraveling transcriptional networks of development and disease. Current Opinion in Hematology. 17: 300-7. PMID 20571393 DOI: 10.1097/Moh.0B013E32833A06F8  0.429
2010 Witt LM, Gutzwiller LM, Gresser AL, Li-Kroeger D, Cook TA, Gebelein B. Atonal, Senseless, and Abdominal-A regulate rhomboid enhancer activity in abdominal sensory organ precursors. Developmental Biology. 344: 1060-70. PMID 20478292 DOI: 10.1016/J.Ydbio.2010.05.011  0.503
2010 Uhl JD, Cook TA, Gebelein B. Comparing anterior and posterior Hox complex formation reveals guidelines for predicting cis-regulatory elements. Developmental Biology. 343: 154-66. PMID 20398649 DOI: 10.1016/J.Ydbio.2010.04.004  0.528
2010 Lomberk GA, Imoto I, Gebelein B, Urrutia R, Cook TA. Conservation of the TGFbeta/Labial homeobox signaling loop in endoderm-derived cells between Drosophila and mammals. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 10: 74-84. PMID 20339309 DOI: 10.1159/000276895  0.434
2010 Chaubey A, Velu CS, Horman S, Jegga A, Guzman ML, Zeleznik-Le N, Jordan CT, Carroll M, Gebelein B, Grimes HL. Intrinsic Requirement of MicroRNA In Hox-Based Leukemia Initiating Cell Maintenance Blood. 116: 4192-4192. DOI: 10.1182/Blood.V116.21.4192.4192  0.395
2009 Horman SR, Velu CS, Chaubey A, Bourdeau T, Zhu J, Paul WE, Gebelein B, Grimes HL. Gfi1 integrates progenitor versus granulocytic transcriptional programming. Blood. 113: 5466-75. PMID 19346496 DOI: 10.1182/Blood-2008-09-179747  0.367
2009 Chaubey A, Velu CS, Horman S, Jegga A, Guzman ML, Risner L, Zeleznik-Le NJ, Jordan CT, Carroll M, Gebelein B, Grimes HL. Epigenetic Signaling Is Required for HoxA9-Based Leukemic Transformation. Blood. 114: 3966-3966. DOI: 10.1182/Blood.V114.22.3966.3966  0.458
2008 Gebelein B. The control of EGF signaling and cell fate in the Drosophila abdomen. Fly. 2: 257-8. PMID 20798606 DOI: 10.4161/Fly.7084  0.41
2008 Li-Kroeger D, Witt LM, Grimes HL, Cook TA, Gebelein B. Hox and senseless antagonism functions as a molecular switch to regulate EGF secretion in the Drosophila PNS. Developmental Cell. 15: 298-308. PMID 18694568 DOI: 10.1016/J.Devcel.2008.06.001  0.503
2008 Grimes HL, Velu CS, Horman S, Chaubey A, Bourdeau T, Xu H, Zhu J, Paul W, Colmenares C, Williams DA, Gebelein B. Gfi1 as a Regulator of Hematopoietic Differentiation. Blood. 112: sci-16-sci-16. DOI: 10.1182/Blood.V112.11.Sci-16.Sci-16  0.469
2008 Chaubey A, Hormon S, Velu CS, Bourdeau T, Zhu J, Paul W, Jegga A, Gebelein B, Grimes HL. GFI1 Is a Tumor Suppressor in Myeloid Progenitors Blood. 112: 2942-2942. DOI: 10.1182/Blood.V112.11.2942.2942  0.423
2007 Xie B, Charlton-Perkins M, McDonald E, Gebelein B, Cook T. Senseless functions as a molecular switch for color photoreceptor differentiation in Drosophila. Development (Cambridge, England). 134: 4243-53. PMID 17978002 DOI: 10.1242/Dev.012781  0.368
2007 Gebelein B, Mann RS. Compartmental modulation of abdominal Hox expression by engrailed and sloppy-paired patterns the fly ectoderm. Developmental Biology. 308: 593-605. PMID 17573068 DOI: 10.1016/J.Ydbio.2007.05.017  0.571
2007 Horman SR, Velu CS, Bourdeau T, Baktula A, Zhu J, Paul W, Jegga A, Caliguiri MA, Gebelein B, Grimes HL. A Conserved Mechanism of Transcription Factor Competition Controls Hematopoietic Progenitor Self-Renewal. Blood. 110: 91-91. DOI: 10.1182/Blood.V110.11.91.91  0.462
2004 Gebelein B, McKay DJ, Mann RS. Direct integration of Hox and segmentation gene inputs during Drosophila development. Nature. 431: 653-9. PMID 15470419 DOI: 10.1038/Nature02946  0.662
2002 Gebelein B, Culi J, Ryoo HD, Zhang W, Mann RS. Specificity of Distalless repression and limb primordia development by abdominal Hox proteins. Developmental Cell. 3: 487-98. PMID 12408801 DOI: 10.1016/S1534-5807(02)00257-5  0.617
2002 Bessa J, Gebelein B, Pichaud F, Casares F, Mann RS. Combinatorial control of Drosophila eye development by eyeless, homothorax, and teashirt. Genes & Development. 16: 2415-27. PMID 12231630 DOI: 10.1101/Gad.1009002  0.632
2001 Gebelein B, Urrutia R. Sequence-specific transcriptional repression by KS1, a multiple-zinc-finger-Krüppel-associated box protein. Molecular and Cellular Biology. 21: 928-39. PMID 11154279 DOI: 10.1128/Mcb.21.3.928-939.2001  0.448
1999 Cook T, Gebelein B, Belal M, Mesa K, Urrutia R. Three conserved transcriptional repressor domains are a defining feature of the TIEG subfamily of Sp1-like zinc finger proteins. The Journal of Biological Chemistry. 274: 29500-4. PMID 10506214 DOI: 10.1074/Jbc.274.41.29500  0.329
1999 Cook T, Gebelein B, Urrutia R. Sp1 and its likes: biochemical and functional predictions for a growing family of zinc finger transcription factors. Annals of the New York Academy of Sciences. 880: 94-102. PMID 10415854 DOI: 10.1111/J.1749-6632.1999.Tb09513.X  0.425
1998 Gebelein B, Fernandez-Zapico M, Imoto M, Urrutia R. KRAB-independent suppression of neoplastic cell growth by the novel zinc finger transcription factor KS1. The Journal of Clinical Investigation. 102: 1911-9. PMID 9835615 DOI: 10.1172/Jci1919  0.322
1998 Cook T, Gebelein B, Mesa K, Mladek A, Urrutia R. Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth. The Journal of Biological Chemistry. 273: 25929-36. PMID 9748269 DOI: 10.1074/Jbc.273.40.25929  0.366
1998 Cook T, Tachibana I, Mesa K, Imoto M, Gebelein B, Tuma A, Urrutia R. Characterization of a highly related family of SP1-like transcriptional repressor proteins from pancreatic epithelial cell populations Gastroenterology. 114: A581. DOI: 10.1016/S0016-5085(98)82365-2  0.339
1996 Gebelein B, Mesa K, Urrutia R. A novel profile of expressed sequence tags for zinc finger encoding genes from the poorly differentiated exocrine pancreatic cell line AR4IP. Cancer Letters. 105: 225-31. PMID 8697448 DOI: 10.1016/0304-3835(96)04286-3  0.385
1996 Mesa K, Gebelein B, Cook T, Urrutia R. Identification and characterization of zinc finger encoding genes from the tumoral exocrine pancreatic cell line AR42J. Cancer Letters. 103: 143-9. PMID 8635150 DOI: 10.1016/0304-3835(96)04204-8  0.41
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