Sheila A. Stewart - Publications

Affiliations: 
Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
Cell Biology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, ... ... Stewart S, et al. A framework for advancing our understanding of cancer-associated fibroblasts. Nature Reviews. Cancer. PMID 31980749 DOI: 10.1038/S41568-019-0238-1  0.31
2019 Faget DV, Ren Q, Stewart SA. Unmasking senescence: context-dependent effects of SASP in cancer. Nature Reviews. Cancer. PMID 31235879 DOI: 10.1038/S41568-019-0156-2  0.385
2018 Murali B, Ren Q, Luo X, Faget DV, Wang C, Johnson RM, Gruosso T, Flanagan KC, Fu Y, Leahy KM, Alspach E, Su X, Ross MH, Burnette B, Weilbaecher KN, ... ... Stewart SA, et al. Inhibition of the stromal p38MAPK/MK2 pathway limits breast cancer metastases and chemotherapy-induced bone loss. Cancer Research. PMID 30093561 DOI: 10.1158/0008-5472.Can-18-0234  0.35
2018 Flanagan KC, Alspach E, Pazolli E, Parajuli S, Ren Q, Arthur LL, Tapia R, Stewart SA. c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors. Oncotarget. 9: 21-36. PMID 29416593 DOI: 10.18632/Oncotarget.22940  0.724
2017 Nickless A, Cheruiyot A, Flanagan KC, Piwnica-Worms D, Stewart SA, You Z. p38 MAPK Inhibits Nonsense-mediated RNA Decay in Response to Persistent DNA Damage in Non-cycling Cells. The Journal of Biological Chemistry. PMID 28765281 DOI: 10.1074/Jbc.M117.787846  0.486
2017 Parajuli S, Tealsey DC, Murali B, Jackson J, Vindigni A, Stewart SA. Human Ribonuclease H1 resolves R loops and thereby enables progression of the DNA replication fork. The Journal of Biological Chemistry. PMID 28717002 DOI: 10.1074/Jbc.M117.787473  0.475
2016 Ruhland MK, Loza AJ, Capietto AH, Luo X, Knolhoff BL, Flanagan KC, Belt BA, Alspach E, Leahy K, Luo J, Schaffer A, Edwards JR, Longmore G, Faccio R, DeNardo DG, ... Stewart SA, et al. Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nature Communications. 7: 11762. PMID 27272654 DOI: 10.1038/Ncomms11762  0.388
2016 Marsh T, Wong I, Sceneay J, Barakat A, Qin Y, Sjödin A, Alspach E, Nilsson B, Stewart SA, McAllister SS. Hematopoietic Age at Onset of Triple-Negative Breast Cancer Dictates Disease Aggressiveness and Progression. Cancer Research. 76: 2932-2943. PMID 27197230 DOI: 10.1158/0008-5472.Can-15-3332  0.356
2016 D'Amico L, Mahajan S, Capietto AH, Yang Z, Zamani A, Ricci B, Bumpass DB, Meyer M, Su X, Wang-Gillam A, Weilbaecher K, Stewart SA, DeNardo DG, Faccio R. Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer. The Journal of Experimental Medicine. PMID 27045006 DOI: 10.1084/Jem.20150950  0.355
2016 Ruhland MK, Coussens LM, Stewart SA. Senescence and cancer: An evolving inflammatory paradox. Biochimica Et Biophysica Acta. 1865: 14-22. PMID 26453912 DOI: 10.1016/J.Bbcan.2015.10.001  0.361
2016 Stewart SA, Murali B, Su X, Flanagan K, Sponagel J, Luo X, Fu Y, Alspach E, Leahy K, Monahan J, Weilbeacher K. Abstract LB-270: Inhibition of the stromal p38MAPK pathway abrogates breast cancer metastases Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-270  0.336
2016 Sceneay J, Marsh T, Wong I, Qin Y, Sjödin A, Nilsson B, Stewart SA, McAllister SS. Abstract 4400: Hematopoietic age at onset of breast cancer dictates disease aggressiveness and progression Cancer Research. 76: 4400-4400. DOI: 10.1158/1538-7445.Am2016-4400  0.337
2015 Luo X, Fu Y, Loza AJ, Murali B, Leahy KM, Ruhland MK, Gang M, Su X, Zamani A, Shi Y, Lavine KJ, Ornitz DM, Weilbaecher KN, Long F, Novack DV, ... ... Stewart SA, et al. Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development. Cell Reports. PMID 26725121 DOI: 10.1016/J.Celrep.2015.12.016  0.317
2015 Teasley DC, Parajuli S, Nguyen M, Moore HR, Alspach E, Lock YJ, Honaker Y, Saharia A, Piwnica-Worms H, Stewart SA. Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand. The Journal of Biological Chemistry. 290: 15133-45. PMID 25922071 DOI: 10.1074/Jbc.M115.647388  0.742
2015 Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, Zellweger R, Moore H, Lee EH, Hendrickson EA, Cejka P, Stewart S, Lopes M, Vindigni A. DNA2 drives processing and restart of reversed replication forks in human cells. The Journal of Cell Biology. 208: 545-62. PMID 25733713 DOI: 10.1083/Jcb.201406100  0.489
2015 Tapia R, Flanagan K, Stewart S. The Role of Wip1 in Regulating the Protumorigenic Senescence-Associated Secretory Phenotype The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.Lb625  0.401
2014 Alspach E, Flanagan KC, Luo X, Ruhland MK, Huang H, Pazolli E, Donlin MJ, Marsh T, Piwnica-Worms D, Monahan J, Novack DV, McAllister SS, Stewart SA. p38MAPK plays a crucial role in stromal-mediated tumorigenesis. Cancer Discovery. 4: 716-29. PMID 24670723 DOI: 10.1158/2159-8290.Cd-13-0743  0.743
2013 Alspach E, Fu Y, Stewart SA. Senescence and the pro-tumorigenic stroma. Critical Reviews in Oncogenesis. 18: 549-58. PMID 24579734 DOI: 10.1615/Critrevoncog.2014010630  0.4
2013 Wildes TM, Paasch J, Fiala MA, Chen L, Vij R, Stockerl-Goldstein KE, Stewart S, Colditz GA, Tomasson M. The Senescence-Associated Secretory Phenotype In Multiple Myeloma Blood. 122: 5357-5357. DOI: 10.1182/Blood.V122.21.5357.5357  0.328
2012 Karanja KK, Cox SW, Duxin JP, Stewart SA, Campbell JL. DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network. Cell Cycle (Georgetown, Tex.). 11: 3983-96. PMID 22987153 DOI: 10.4161/Cc.22215  0.761
2012 Duxin JP, Moore HR, Sidorova J, Karanja K, Honaker Y, Dao B, Piwnica-Worms H, Campbell JL, Monnat RJ, Stewart SA. Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication. The Journal of Biological Chemistry. 287: 21980-91. PMID 22570476 DOI: 10.1074/Jbc.M112.359018  0.781
2012 Pazolli E, Alspach E, Milczarek A, Prior J, Piwnica-Worms D, Stewart SA. Chromatin remodeling underlies the senescence-associated secretory phenotype of tumor stromal fibroblasts that supports cancer progression. Cancer Research. 72: 2251-61. PMID 22422937 DOI: 10.1158/0008-5472.Can-11-3386  0.751
2011 Luo X, Ruhland MK, Pazolli E, Lind AC, Stewart SA. Osteopontin stimulates preneoplastic cellular proliferation through activation of the MAPK pathway. Molecular Cancer Research : McR. 9: 1018-29. PMID 21673011 DOI: 10.1158/1541-7786.Mcr-10-0472  0.744
2011 Lee S, Stewart S, Luo J, Medina D, Allred DC. Abstract A55: Genes regulating the progression of human ductal carcinoma in situ to invasive breast cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-A55  0.33
2010 Stewart SA, Bertuch AA. The role of telomeres and telomerase in cancer research. Cancer Research. 70: 7365-71. PMID 20841475 DOI: 10.1158/0008-5472.Can-10-1373  0.458
2010 Saharia A, Teasley DC, Duxin JP, Dao B, Chiappinelli KB, Stewart SA. FEN1 ensures telomere stability by facilitating replication fork re-initiation. The Journal of Biological Chemistry. 285: 27057-66. PMID 20551483 DOI: 10.1074/Jbc.M110.112276  0.763
2010 Nittis T, Guittat L, LeDuc RD, Dao B, Duxin JP, Rohrs H, Townsend RR, Stewart SA. Revealing novel telomere proteins using in vivo cross-linking, tandem affinity purification, and label-free quantitative LC-FTICR-MS. Molecular & Cellular Proteomics : McP. 9: 1144-56. PMID 20097687 DOI: 10.1074/Mcp.M900490-Mcp200  0.729
2009 Duxin JP, Dao B, Martinsson P, Rajala N, Guittat L, Campbell JL, Spelbrink JN, Stewart SA. Human Dna2 is a nuclear and mitochondrial DNA maintenance protein. Molecular and Cellular Biology. 29: 4274-82. PMID 19487465 DOI: 10.1128/Mcb.01834-08  0.754
2009 Pazolli E, Luo X, Brehm S, Carbery K, Chung JJ, Prior JL, Doherty J, Demehri S, Salavaggione L, Piwnica-Worms D, Stewart SA. Senescent stromal-derived osteopontin promotes preneoplastic cell growth. Cancer Research. 69: 1230-9. PMID 19155301 DOI: 10.1158/0008-5472.Can-08-2970  0.747
2009 Saharia A, Stewart SA. FEN1 contributes to telomere stability in ALT-positive tumor cells. Oncogene. 28: 1162-7. PMID 19137021 DOI: 10.1038/Onc.2008.458  0.731
2008 Saharia A, Guittat L, Crocker S, Lim A, Steffen M, Kulkarni S, Stewart SA. Flap endonuclease 1 contributes to telomere stability. Current Biology : Cb. 18: 496-500. PMID 18394896 DOI: 10.1016/J.Cub.2008.02.071  0.747
2008 Pazolli E, Stewart SA. Senescence: the good the bad and the dysfunctional. Current Opinion in Genetics & Development. 18: 42-7. PMID 18262406 DOI: 10.1016/J.Gde.2007.12.002  0.741
2008 Nittis T, Guittat L, Stewart SA. Alternative lengthening of telomeres (ALT) and chromatin: is there a connection? Biochimie. 90: 5-12. PMID 17935854 DOI: 10.1016/J.Biochi.2007.08.009  0.406
2006 Stewart SA, Weinberg RA. Telomeres: cancer to human aging. Annual Review of Cell and Developmental Biology. 22: 531-57. PMID 16824017 DOI: 10.1146/Annurev.Cellbio.22.010305.104518  0.463
2005 Zaehres H, Lensch MW, Daheron L, Stewart SA, Itskovitz-Eldor J, Daley GQ. High-efficiency RNA interference in human embryonic stem cells. Stem Cells (Dayton, Ohio). 23: 299-305. PMID 15749924 DOI: 10.1634/Stemcells.2004-0252  0.323
2003 Masutomi K, Yu EY, Khurts S, Ben-Porath I, Currier JL, Metz GB, Brooks MW, Kaneko S, Murakami S, DeCaprio JA, Weinberg RA, Stewart SA, Hahn WC. Telomerase maintains telomere structure in normal human cells. Cell. 114: 241-53. PMID 12887925 DOI: 10.1016/S0092-8674(03)00550-6  0.328
2003 Stewart SA, Ben-Porath I, Carey VJ, O'Connor BF, Hahn WC, Weinberg RA. Erosion of the telomeric single-strand overhang at replicative senescence. Nature Genetics. 33: 492-6. PMID 12652299 DOI: 10.1038/Ng1127  0.317
2002 Stewart SA. Multiple levels of telomerase regulation. Molecular Interventions. 2: 481-3. PMID 14993399 DOI: 10.1124/mi.2.8.481  0.319
2002 Stewart SA, Hahn WC, O'Connor BF, Banner EN, Lundberg AS, Modha P, Mizuno H, Brooks MW, Fleming M, Zimonjic DB, Popescu NC, Weinberg RA. Telomerase contributes to tumorigenesis by a telomere length-independent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 99: 12606-11. PMID 12193655 DOI: 10.1073/Pnas.182407599  0.304
2002 Stewart SA, Hahn WC. Prospects for anti-neoplastic therapies based on telomere biology. Current Cancer Drug Targets. 2: 1-17. PMID 12188917 DOI: 10.2174/1568009023334015  0.306
2002 Stewart SA, Weinberg RA. Senescence: does it all happen at the ends? Oncogene. 21: 627-30. PMID 11850788 DOI: 10.1038/Sj.Onc.1205062  0.313
2001 Johnson FB, Marciniak RA, McVey M, Stewart SA, Hahn WC, Guarente L. The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase. The Embo Journal. 20: 905-13. PMID 11179234 DOI: 10.1093/Emboj/20.4.905  0.345
2000 Stewart SA, Weinberg RA. Telomerase and human tumorigenesis Seminars in Cancer Biology. 10: 399-406. PMID 11170862 DOI: 10.1006/Scbi.2000.0339  0.436
1999 Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, Kurachi A, Beijersbergen RL, Knoll JH, Meyerson M, Weinberg RA. Inhibition of telomerase limits the growth of human cancer cells. Nature Medicine. 5: 1164-70. PMID 10502820 DOI: 10.1038/13495  0.349
1987 Thompson LH, Salazar EP, Brookman KW, Collins CC, Stewart SA, Busch DB, Weber CA. Recent progress with the DNA repair mutants of Chinese hamster ovary cells. Journal of Cell Science. Supplement. 6: 97-110. PMID 3477565 DOI: 10.1242/jcs.1984.Supplement_6.6  0.352
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