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Peter O. Krutzik, Ph.D. - Publications

Affiliations: 
2006 Stanford University, Palo Alto, CA 
Area:
Immunology, Cell Biology, Pharmacology
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Estevam J, Krutzik P, Vander Tuig J, McAuliffe WJ, Smithson G. Development and validation of a high-parameter mass cytometry workflow to decipher immunomodulatory changes in celiac disease. Cytometry. Part B, Clinical Cytometry. 100: 92-102. PMID 33452759 DOI: 10.1002/cyto.b.21986  0.306
2020 Chen H, Schürch CM, Noble K, Kim K, Krutzik PO, O'Donnell E, Vander Tuig J, Nolan GP, McIlwain DR. Functional comparison of PBMCs isolated by Cell Preparation Tubes (CPT) vs. Lymphoprep Tubes. Bmc Immunology. 21: 15. PMID 32228458 DOI: 10.1186/S12865-020-00345-0  0.731
2019 Ding X, Krutzik PO, Ghaffari AA, Zhaozhi Y, Miranda D, Cheng G, Ho CM, Nolan GP, Sanchez DJ. Cellular Signaling Analysis shows antiviral, ribavirin-mediated ribosomal signaling modulation. Antiviral Research. 104598. PMID 31513822 DOI: 10.1016/J.Antiviral.2019.104598  0.524
2019 Hartmann FJ, Babdor J, Gherardini PF, Amir ED, Jones K, Sahaf B, Marquez DM, Krutzik P, O'Donnell E, Sigal N, Maecker HT, Meyer E, Spitzer MH, Bendall SC. Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy. Cell Reports. 28: 819-831.e4. PMID 31315057 DOI: 10.1016/J.Celrep.2019.06.049  0.761
2018 Knoerzer D, Teresk M, Krutzik P, O’Donnell E, DeCrescenzo G, Welsch D, Emery C. Abstract B085: Preclinical pharmacokinetic/pharmacodynamic (PK/PD) relationship demonstrated for BVD-723, a potent and selective phosphoinositide 3-kinase gamma (PI3Kγ) inhibitor Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B085  0.348
2017 Moraga I, Spangler JB, Mendoza JL, Gakovic M, Wehrman TS, Krutzik P, Garcia KC. Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers. Elife. 6. PMID 28498099 DOI: 10.7554/Elife.22882  0.32
2015 Moraga I, Wernig G, Wilmes S, Gryshkova V, Richter CP, Hong WJ, Sinha R, Guo F, Fabionar H, Wehrman TS, Krutzik P, Demharter S, Plo I, Weissman IL, Minary P, et al. Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands. Cell. 160: 1196-208. PMID 25728669 DOI: 10.1016/J.Cell.2015.02.011  0.308
2014 O'Donnell EA, Alvendia EL, Wehrman TS, Krutzik PO. Defining the Cell Surface Landscape in B-Cell Malignancies: Comprehensive Profiling of Surface Antigens for Biomarker Discovery and Patient Stratification Blood. 124: 5183-5183. DOI: 10.1182/Blood.V124.21.5183.5183  0.776
2014 Wehrman TS, O'Donnell EA, Lumpe MJ, Osetek BE, Krutzik PO. Abstract 5385: A novel cell-based kinase assay panel paired with high content phenotypic profiling to correlate kinase inhibitor specificity and cellular activity Cancer Research. 74: 5385-5385. DOI: 10.1158/1538-7445.Am2014-5385  0.756
2014 O'Donnell EA, Alvendia EL, Osetek BE, Wehrman TS, Krutzik PO. Abstract 2496: Defining the cell surface landscape in cancer: Comprehensive profiling of surface antigens for biomarker discovery and immune monitoring Cancer Research. 74: 2496-2496. DOI: 10.1158/1538-7445.Am2014-2496  0.777
2012 Kinoshita SM, Krutzik PO, Nolan GP. COP9 signalosome component JAB1/CSN5 is necessary for T cell signaling through LFA-1 and HIV-1 replication. Plos One. 7: e41725. PMID 22911848 DOI: 10.1371/Journal.Pone.0041725  0.496
2012 Bodenmiller B, Zunder ER, Finck R, Chen TJ, Savig ES, Bruggner RV, Simonds EF, Bendall SC, Sachs K, Krutzik PO, Nolan GP. Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators. Nature Biotechnology. 30: 858-67. PMID 22902532 DOI: 10.1038/Nbt.2317  0.745
2012 Schulz KR, Danna EA, Krutzik PO, Nolan GP. Single-cell phospho-protein analysis by flow cytometry. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 8.17.1-20. PMID 22314834 DOI: 10.1002/0471142735.Im0817S96  0.627
2011 Thomas C, Moraga I, Levin D, Krutzik PO, Podoplelova Y, Trejo A, Lee C, Yarden G, Vleck SE, Glenn JS, Nolan GP, Piehler J, Schreiber G, Garcia KC. Structural linkage between ligand discrimination and receptor activation by type I interferons. Cell. 146: 621-32. PMID 21854986 DOI: 10.1016/J.Cell.2011.06.048  0.504
2011 Bendall SC, Simonds EF, Qiu P, Amir el-AD, Krutzik PO, Finck R, Bruggner RV, Melamed R, Trejo A, Ornatsky OI, Balderas RS, Plevritis SK, Sachs K, Pe'er D, Tanner SD, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science (New York, N.Y.). 332: 687-96. PMID 21551058 DOI: 10.1126/Science.1198704  0.771
2011 Krutzik PO, Clutter MR, Trejo A, Nolan GP. Fluorescent cell barcoding for multiplex flow cytometry. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 6.31. PMID 21207359 DOI: 10.1002/0471142956.Cy0631S55  0.561
2011 Krutzik PO, Trejo A, Schulz KR, Nolan GP. Phospho flow cytometry methods for the analysis of kinase signaling in cell lines and primary human blood samples. Methods in Molecular Biology (Clifton, N.J.). 699: 179-202. PMID 21116984 DOI: 10.1007/978-1-61737-950-5_9  0.664
2010 Clutter MR, Heffner GC, Krutzik PO, Sachen KL, Nolan GP. Tyramide signal amplification for analysis of kinase activity by intracellular flow cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 1020-31. PMID 20824632 DOI: 10.1002/Cyto.A.20970  0.63
2010 O'Gorman WE, Sampath P, Simonds EF, Sikorski R, O'Malley M, Krutzik PO, Chen H, Panchanathan V, Chaudhri G, Karupiah G, Lewis DB, Thorne SH, Nolan GP. Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses. Cell Host & Microbe. 8: 174-85. PMID 20709294 DOI: 10.1016/J.Chom.2010.07.008  0.711
2010 Kotecha N, Krutzik PO, Irish JM. Web-based analysis and publication of flow cytometry experiments. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit10.17. PMID 20578106 DOI: 10.1002/0471142956.Cy1017S53  0.709
2010 Krutzik PO, Bendall SC, Hale MB, Irish JM, Nolan GP. Phospho Flow Cytometry: Single-Cell Signaling Networks in Next-Generation Drug Discovery and Patient Stratification Flow Cytometry in Drug Discovery and Development. 303-334. DOI: 10.1002/9780470910085.ch15  0.634
2009 Hale MB, Krutzik PO, Samra SS, Crane JM, Nolan GP. Stage dependent aberrant regulation of cytokine-STAT signaling in murine systemic lupus erythematosus. Plos One. 4: e6756. PMID 19707593 DOI: 10.1371/Journal.Pone.0006756  0.551
2009 O'Gorman WE, Dooms H, Thorne SH, Kuswanto WF, Simonds EF, Krutzik PO, Nolan GP, Abbas AK. The initial phase of an immune response functions to activate regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 332-9. PMID 19542444 DOI: 10.4049/Jimmunol.0900691  0.719
2009 Hammer MM, Kotecha N, Irish JM, Nolan GP, Krutzik PO. WebFlow: a software package for high-throughput analysis of flow cytometry data. Assay and Drug Development Technologies. 7: 44-55. PMID 19187010 DOI: 10.1089/Adt.2008.174  0.755
2008 Krutzik PO, Crane JM, Clutter MR, Nolan GP. High-content single-cell drug screening with phosphospecific flow cytometry. Nature Chemical Biology. 4: 132-42. PMID 18157122 DOI: 10.1038/Nchembio.2007.59  0.604
2007 Schulz KR, Danna EA, Krutzik PO, Nolan GP. Single-cell phospho-protein analysis by flow cytometry. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 8.17. PMID 18432997 DOI: 10.1002/0471142735.Im0817S78  0.627
2007 Hale M, Krutzik P, Nolan G. Cell-type Specific Changes in Cytokine-STAT Signal Transduction Stage Systemic Lupus Erythematosus Clinical Immunology. 123: S138-S139. DOI: 10.1016/J.Clim.2007.03.032  0.528
2006 Krutzik PO, Nolan GP. Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling. Nature Methods. 3: 361-8. PMID 16628206 DOI: 10.1038/Nmeth872  0.637
2006 Wehrman TS, von Degenfeld G, Krutzik PO, Nolan GP, Blau HM. Luminescent imaging of beta-galactosidase activity in living subjects using sequential reporter-enzyme luminescence. Nature Methods. 3: 295-301. PMID 16554835 DOI: 10.1038/Nmeth868  0.447
2005 Clutter MR, Krutzik PO, Nolan GP. Phospho-specific flow cytometry in drug discovery. Drug Discovery Today. Technologies. 2: 295-302. PMID 24981951 DOI: 10.1016/J.Ddtec.2005.08.010  0.532
2005 Krutzik PO, Hale MB, Nolan GP. Characterization of the murine immunological signaling network with phosphospecific flow cytometry. Journal of Immunology (Baltimore, Md. : 1950). 175: 2366-73. PMID 16081807 DOI: 10.4049/Jimmunol.175.4.2366  0.637
2005 Krutzik PO, Clutter MR, Nolan GP. Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry. Journal of Immunology (Baltimore, Md. : 1950). 175: 2357-65. PMID 16081806 DOI: 10.4049/Jimmunol.175.4.2357  0.595
2005 Stitz J, Krutzik PO, Nolan GP. Screening of retroviral cDNA libraries for factors involved in protein phosphorylation in signaling cascades. Nucleic Acids Research. 33: e39. PMID 15731332 DOI: 10.1093/Nar/Gni039  0.591
2005 Irish J, Hovland R, Krutzik P, Perez O, Bruserud O, Gjertsen B, Nolan G. Potentiated phospho-protein networks in cancer cells Breast Cancer Research. 7: 1-1. DOI: 10.1186/Bcr1194  0.669
2004 Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud Ø, Gjertsen BT, Nolan GP. Single cell profiling of potentiated phospho-protein networks in cancer cells Cell. 118: 217-228. PMID 15260991 DOI: 10.1016/J.Cell.2004.06.028  0.671
2004 Krutzik PO, Irish JM, Nolan GP, Perez OD. Analysis of protein phosphorylation and cellular signaling events by flow cytometry: Techniques and clinical applications Clinical Immunology. 110: 206-221. PMID 15047199 DOI: 10.1016/J.Clim.2003.11.009  0.701
2004 Perez OD, Krutzik PO, Nolan GP. Flow cytometric analysis of kinase signaling cascades. Methods in Molecular Biology (Clifton, N.J.). 263: 67-94. PMID 14976361 DOI: 10.1385/1-59259-773-4:067  0.617
2003 Krutzik PO, Nolan GP. Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 55: 61-70. PMID 14505311 DOI: 10.1002/Cyto.A.10072  0.609
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