Kenneth W. Witwer, Ph.D. - Publications

2010 Johns Hopkins University, Baltimore, MD 
Molecular Biology, Virology Biology, Cell Biology

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Beck SE, Queen SE, Metcalf Pate KA, Mangus LM, Abreu CM, Gama L, Witwer KW, Adams RJ, Zink MC, Clements JE, Mankowski JL. An SIV/macaque model targeted to study HIV-associated neurocognitive disorders. Journal of Neurovirology. PMID 28975505 DOI: 10.1007/S13365-017-0582-4  0.8
2016 McCall MN, Baras AS, Crits-Christoph A, Ingersoll R, McAlexander MA, Witwer KW, Halushka MK. A benchmark for microRNA quantification algorithms using the OpenArray platform. Bmc Bioinformatics. 17: 138. PMID 27000067 DOI: 10.1186/S12859-016-0987-8  0.8
2016 Aragon Han P, Kim HS, Cho S, Fazeli R, Najafian A, Khawaja H, McAlexander M, Dy B, Sorensen M, Aronova A, Sebo TJ, Giordano TJ, Fahey TJ, Thompson GB, Gauger PG, ... ... Witwer KW, et al. Association of BRAF(V600E) Mutation and MicroRNA Expression with Central Lymph Node Metastases in Papillary Thyroid Cancer: A Prospective Study from Four Endocrine Surgery Centers. Thyroid : Official Journal of the American Thyroid Association. PMID 26950846 DOI: 10.1089/Thy.2015.0378  0.8
2016 Buchanan EL, Espinoza DA, McAlexander MA, Myers SL, Moyer A, Witwer KW. SAMHD1 transcript upregulation during SIV infection of the central nervous system does not associate with reduced viral load. Scientific Reports. 6: 22629. PMID 26936683 DOI: 10.1038/Srep22629  0.8
2015 Witwer KW. Contamination or artifacts may explain reports of plant miRNAs in humans. The Journal of Nutritional Biochemistry. 26: 1685. PMID 26456566 DOI: 10.1016/J.Jnutbio.2015.09.004  0.8
2015 Sherman JH, Munyikwa T, Chan SY, Petrick JS, Witwer KW, Choudhuri S. RNAi Technologies in Agricultural Biotechnology: The Toxicology Forum 40(th) Annual Summer Meeting. Regulatory Toxicology and Pharmacology : Rtp. PMID 26361858 DOI: 10.1016/J.Yrtph.2015.09.001  0.8
2015 Witwer KW, Buchanan EL, Myers SL, McAlexander MA. miRNAs and SAMHD1 regulation in vitro and in a model of HIV CNS disease. Journal of Neuroinflammation. 12: 159. PMID 26337901 DOI: 10.1186/S12974-015-0380-Y  0.8
2015 Lee YJ, Kim V, Muth DC, Witwer KW. Validated MicroRNA Target Databases: An Evaluation. Drug Development Research. 76: 389-96. PMID 26286669 DOI: 10.1002/Ddr.21278  0.8
2015 Muth DC, McAlexander MA, Ostrenga LJ, Pate NM, Izzi JM, Adams RJ, Pate KA, Beck SE, Karim BO, Witwer KW. Potential role of cervicovaginal extracellular particles in diagnosis of endometriosis. Bmc Veterinary Research. 11: 187. PMID 26253321 DOI: 10.1186/S12917-015-0513-7  0.8
2015 El-Diwany R, Wasilewski L, Witwer KW, Bailey JR, Page K, Ray SC, Cox AL, Thomas DL, Balagopal A. Acute Hepatitis C Virus Infection Induces Consistent Changes in Circulating miRNAs that are Associated with Non-Lytic Hepatocyte Release. Journal of Virology. PMID 26157120 DOI: 10.1128/Jvi.00955-15  0.8
2015 Tosar JP, Gámbaro F, Sanguinetti J, Bonilla B, Witwer KW, Cayota A. Assessment of small RNA sorting into different extracellular fractions revealed by high-throughput sequencing of breast cell lines. Nucleic Acids Research. 43: 5601-16. PMID 25940616 DOI: 10.1093/Nar/Gkv432  0.8
2015 Beck SE, Queen SE, Witwer KW, Metcalf Pate KA, Mangus LM, Gama L, Adams RJ, Clements JE, Christine Zink M, Mankowski JL. Paving the path to HIV neurotherapy: Predicting SIV CNS disease. European Journal of Pharmacology. 759: 303-12. PMID 25818747 DOI: 10.1016/J.Ejphar.2015.03.018  0.8
2015 Drewes JL, Meulendyke KA, Liao Z, Witwer KW, Gama L, Ubaida-Mohien C, Li M, Notarangelo FM, Tarwater PM, Schwarcz R, Graham DR, Zink MC. Quinolinic acid/tryptophan ratios predict neurological disease in SIV-infected macaques and remain elevated in the brain under cART. Journal of Neurovirology. PMID 25776527 DOI: 10.1007/S13365-015-0334-2  0.8
2015 Witwer KW. Circulating microRNA biomarker studies: pitfalls and potential solutions. Clinical Chemistry. 61: 56-63. PMID 25391989 DOI: 10.1373/Clinchem.2014.221341  0.8
2015 Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, Kim JH, Go G, Nhung D, Hong K, Jang SC, Kim SH, Park KS, Kim OY, Park HT, Seo JH, ... ... Witwer K, et al. EVpedia: a community web portal for extracellular vesicles research. Bioinformatics (Oxford, England). 31: 933-9. PMID 25388151 DOI: 10.1093/Bioinformatics/Btu741  0.8
2015 Buchanan EL, McAlexander MA, Witwer KW. SAMHD1 expression in blood cells of HIV-1 elite suppressors and viraemic progressors. The Journal of Antimicrobial Chemotherapy. 70: 954-6. PMID 25344600 DOI: 10.1093/Jac/Dku428  0.8
2014 Witwer KW. Diet-responsive mammalian miRNAs are likely endogenous. The Journal of Nutrition. 144: 1880-1. PMID 25332488 DOI: 10.3945/Jn.114.202523  0.8
2014 Christofidou-Solomidou M, Pietrofesa R, Arguiri E, McAlexander MA, Witwer KW. Dietary flaxseed modulates the miRNA profile in irradiated and non-irradiated murine lungs: a novel mechanism of tissue radioprotection by flaxseed. Cancer Biology & Therapy. 15: 930-7. PMID 24755684 DOI: 10.4161/Cbt.28905  0.8
2014 Witwer KW, Gama L, Mankowski JL, Zink MC, Clements JE. TRIM19-positive and TRIM19-negative cells in and around a perivascular cuff of CD68-positive macrophages. Aids Research and Human Retroviruses. 30: 333-4. PMID 24697643 DOI: 10.1089/Aid.2014.0029  0.8
2014 Meulendyke KA, Ubaida-Mohien C, Drewes JL, Liao Z, Gama L, Witwer KW, Graham DR, Zink MC. Elevated brain monoamine oxidase activity in SIV- and HIV-associated neurological disease. The Journal of Infectious Diseases. 210: 904-12. PMID 24688074 DOI: 10.1093/Infdis/Jiu194  0.8
2014 Witwer KW. HIV-1 Tat- and Vpr-responsive microRNAs of neuronal cells. The Journal of Biological Chemistry. 289: 3104. PMID 24489003 DOI: 10.1074/Jbc.L113.541755  0.8
2014 Witwer KW, Hirschi KD. Transfer and functional consequences of dietary microRNAs in vertebrates: concepts in search of corroboration: negative results challenge the hypothesis that dietary xenomiRs cross the gut and regulate genes in ingesting vertebrates, but important questions persist. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 36: 394-406. PMID 24436255 DOI: 10.1002/Bies.201300150  0.8
2014 Yu IW, Espinoza DA, McAlexander MA, Witwer KW. OpenArray profiling reveals no differential modulation of miRNA by positive and negative CD4+ T cell immunoselection. Experimental Hematology. 42: 11-3. PMID 24096121 DOI: 10.1016/J.Exphem.2013.09.011  0.8
2013 Liu J, Sisk JM, Gama L, Clements JE, Witwer KW. Tristetraprolin expression and microRNA-mediated regulation during simian immunodeficiency virus infection of the central nervous system. Molecular Brain. 6: 40. PMID 24103357 DOI: 10.1186/1756-6606-6-40  0.8
2013 Sisk JM, Witwer KW, Tarwater PM, Clements JE. SIV replication is directly downregulated by four antiviral miRNAs. Retrovirology. 10: 95. PMID 23988154 DOI: 10.1186/1742-4690-10-95  0.8
2013 Witwer KW, McAlexander MA, Queen SE, Adams RJ. Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs: limited evidence for general uptake of dietary plant xenomiRs. Rna Biology. 10: 1080-6. PMID 23770773 DOI: 10.4161/Rna.25246  0.8
2013 McAlexander MA, Phillips MJ, Witwer KW. Comparison of Methods for miRNA Extraction from Plasma and Quantitative Recovery of RNA from Cerebrospinal Fluid. Frontiers in Genetics. 4: 83. PMID 23720669 DOI: 10.3389/Fgene.2013.00083  0.8
2013 Witwer KW. Data submission and quality in microarray-based microRNA profiling. Clinical Chemistry. 59: 392-400. PMID 23358751 DOI: 10.1373/Clinchem.2012.193813  0.8
2012 Sisk JM, Clements JE, Witwer KW. miRNA profiles of monocyte-lineage cells are consistent with complicated roles in HIV-1 restriction. Viruses. 4: 1844-64. PMID 23202444 DOI: 10.3390/V4101844  0.8
2012 Witwer KW. XenomiRs and miRNA homeostasis in health and disease: evidence that diet and dietary miRNAs directly and indirectly influence circulating miRNA profiles. Rna Biology. 9: 1147-54. PMID 22951590 DOI: 10.4161/Rna.21619  0.8
2012 Witwer KW, Clements JE. Evidence for miRNA expression differences of HIV-1-positive, treatment-naive patients and elite suppressors: a re-analysis. Blood. 119: 6395-6. PMID 22745299 DOI: 10.1182/Blood-2012-02-412742  0.8
2012 Witwer KW, Watson AK, Blankson JN, Clements JE. Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients. Retrovirology. 9: 5. PMID 22240256 DOI: 10.1186/1742-4690-9-5  0.8
2012 Watson AK, Witwer KW. Do platform-specific factors explain microRNA profiling disparities? Clinical Chemistry. 58: 472-4; author reply . PMID 22048406 DOI: 10.1373/Clinchem.2011.175281  0.8
2011 Co JG, Witwer KW, Gama L, Zink MC, Clements JE. Induction of innate immune responses by SIV in vivo and in vitro: differential expression and function of RIG-I and MDA5. The Journal of Infectious Diseases. 204: 1104-14. PMID 21881126 DOI: 10.1093/Infdis/Jir469  0.8
2011 Witwer KW, Sarbanes SL, Liu J, Clements JE. A plasma microRNA signature of acute lentiviral infection: biomarkers of central nervous system disease. Aids (London, England). 25: 2057-67. PMID 21857495 DOI: 10.1097/Qad.0B013E32834B95Bf  0.8
2010 Witwer KW, Sisk JM, Gama L, Clements JE. MicroRNA regulation of IFN-beta protein expression: rapid and sensitive modulation of the innate immune response. Journal of Immunology (Baltimore, Md. : 1950). 184: 2369-76. PMID 20130213 DOI: 10.4049/Jimmunol.0902712  0.8
2009 Witwer KW, Gama L, Li M, Bartizal CM, Queen SE, Varrone JJ, Brice AK, Graham DR, Tarwater PM, Mankowski JL, Zink MC, Clements JE. Coordinated regulation of SIV replication and immune responses in the CNS. Plos One. 4: e8129. PMID 20019816 DOI: 10.1371/Journal.Pone.0008129  0.8
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