Douglas H. Smith - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 

234 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Song H, Tomasevich A, Acheampong KK, Schaff DL, Shaffer SM, Dolle JP, Johnson VE, Mikytuck B, Lee EB, Nolan A, Keene CD, Weiss SR, Stewart W, Smith DH. Detection of blood-brain barrier disruption in brains of patients with COVID-19, but no evidence of brain penetration by SARS-CoV-2. Acta Neuropathologica. PMID 37624381 DOI: 10.1007/s00401-023-02624-7  0.701
2023 Harris JP, Mietus CJ, Browne KD, Wofford KL, Keating CE, Brown DP, Johnson BN, Wolf JA, Smith DH, Cohen AS, Duda JE, Cullen DK. Neuronal somatic plasmalemmal permeability and dendritic beading caused by head rotational traumatic brain injury in pigs-An exploratory study. Frontiers in Cellular Neuroscience. 17: 1055455. PMID 37519631 DOI: 10.3389/fncel.2023.1055455  0.732
2023 Culkin MC, Bele P, Georges AP, Lopez AJ, Niziolek G, Jacovides CL, Song H, Johnson VE, Kaplan LJ, Smith DH, Pascual JL. EARLY POST-TRAUMATIC BRAIN INJURY TXA PREVENTS BLOOD BRAIN BARRIER HYPERPERMEABILITY AND SURROGATES OF NEUROCLINICAL RECOVERY. The Journal of Trauma and Acute Care Surgery. PMID 37038259 DOI: 10.1097/TA.0000000000003971  0.746
2022 Smith DH, Burrell JC, Browne KD, Katiyar KS, Ezra MI, Dutton JL, Morand JP, Struzyna LA, Laimo FA, Chen HI, Wolf JA, Kaplan HM, Rosen JM, Ledebur HC, Zager EL, et al. Tissue-engineered grafts exploit axon-facilitated axon regeneration and pathway protection to enable recovery after 5-cm nerve defects in pigs. Science Advances. 8: eabm3291. PMID 36332027 DOI: 10.1126/sciadv.abm3291  0.802
2022 Song H, McEwan PP, Ameen-Ali KE, Tomasevich A, Kennedy-Dietrich C, Palma A, Arroyo EJ, Dolle JP, Johnson VE, Stewart W, Smith DH. Concussion leads to widespread axonal sodium channel loss and disruption of the node of Ranvier. Acta Neuropathologica. PMID 36107227 DOI: 10.1007/s00401-022-02498-1  0.765
2022 Lopez AJ, ElSaadani M, Culkin MC, Jacovides CL, Georges AP, Song H, Kaplan LJ, Kumar MA, Smith DH, Pascual JL. Persistent Blunting of Penumbral Leukocyte Mobilization by Beta Blockade Administered for 2 Weeks After TBI. The Journal of Surgical Research. 280: 196-203. PMID 35994981 DOI: 10.1016/j.jss.2022.06.069  0.74
2022 Song H, Chen C, Kelley B, Tomasevich A, Lee H, Dolle JP, Cheng J, Garcia B, Meaney DF, Smith DH. Traumatic brain injury recapitulates developmental changes of axons. Progress in Neurobiology. 217: 102332. PMID 35870679 DOI: 10.1016/j.pneurobio.2022.102332  0.757
2022 Jgamadze D, Johnson VE, Wolf JA, Cullen DK, Song H, Ming GL, Smith DH, Chen HI. Modeling traumatic brain injury with human brain organoids. Current Opinion in Biomedical Engineering. 14: 52-58. PMID 35434439 DOI: 10.1016/j.cobme.2020.05.004  0.714
2022 Mayer AR, Ling JM, Patton DA, Stephenson DD, Dodd AB, Dodd RJ, Rannou-Latella JG, Smith DH, Johnson VE, Cullen DK, Meier TB, Kinsler RE. Non-Linear Device Head Coupling and Temporal Delays in Large Animal Acceleration Models of Traumatic Brain Injury. Annals of Biomedical Engineering. PMID 35366746 DOI: 10.1007/s10439-022-02953-w  0.476
2022 Lopez AJ, ElSaadani M, Jacovides CL, George A, Culkin MC, Ahmed S, Kumar MA, Kaplan LJ, Smith DH, Pascual JL. BETABLOCKADE IN TBI: DOSE DEPENDENT REDUCTIONS IN BBB LEUKOCYTE MOBILIZATION AND PERMEABILITY IN VIVO. The Journal of Trauma and Acute Care Surgery. PMID 35045056 DOI: 10.1097/TA.0000000000003537  0.326
2021 Kant A, Johnson VE, Arena JD, Dollé JP, Smith DH, Shenoy VB. Modeling links softening of myelin and spectrin scaffolds of axons after a concussion to increased vulnerability to repeated injuries. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34234016 DOI: 10.1073/pnas.2024961118  0.407
2021 Smith DH, Kochanek PM, Rosi S, Meyer R, Ferland-Beckham C, Prager EM, Ahlers S, Crawford FC. Roadmap for Advancing Preclinical Science in Traumatic Brain Injury. Journal of Neurotrauma. PMID 34210174 DOI: 10.1089/neu.2021.0094  0.325
2021 Mayer AR, Ling JM, Dodd AB, Rannou-Latella JG, Stephenson DD, Dodd RJ, Mehos CJ, Patton DA, Cullen DK, Johnson VE, Pabbathi Reddy S, Robertson-Benta CR, Gigliotti AP, Meier TB, Vermillion MS, ... Smith DH, et al. Reproducibility and Characterization of Head Kinematics During a Large Animal Acceleration Model of Traumatic Brain Injury. Frontiers in Neurology. 12: 658461. PMID 34177763 DOI: 10.3389/fneur.2021.658461  0.565
2021 Smith DH, Dollé JP, Ameen-Ali KE, Bretzin A, Cortes E, Crary JF, Dams-O'Connor K, Diaz-Arrastia R, Edlow BL, Folkerth R, Hazrati LN, Hinds SR, Iacono D, Johnson VE, Keene CD, et al. COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI). Acta Neuropathologica Communications. 9: 32. PMID 33648593 DOI: 10.1186/s40478-021-01122-9  0.351
2021 Katiyar K, Burrell JC, Laimo F, Browne K, Bianchi J, Walters A, Ayares DL, Smith DH, Ali Z, Ledebur HC, Cullen DK. Biomanufacturing of axon-based tissue engineered nerve grafts using porcine GalSafe® neurons. Tissue Engineering. Part A. PMID 33514288 DOI: 10.1089/ten.TEA.2020.0303  0.813
2021 Zadnik Sullivan P, Albayar A, Burrell JC, Browne K, Arena J, Johnson V, Smith DH, Cullen DK, Ozturk AK. Implantation Of Engineered Axon Tracts To Bridge Spinal Cord Injury Beyond The Glial Scar In Rats. Tissue Engineering. Part A. PMID 33430694 DOI: 10.1089/ten.TEA.2020.0233  0.772
2020 Arena JD, Johnson VE, Lee EB, Gibbons GS, Smith DH, Trojanowski JQ, Stewart W. Astroglial tau pathology alone preferentially concentrates at sulcal depths in chronic traumatic encephalopathy neuropathologic change. Brain Communications. 2: fcaa210. PMID 33426528 DOI: 10.1093/braincomms/fcaa210  0.315
2020 LaPlaca MC, Huie JR, Alam HB, Bachstetter AD, Bayir H, Bellgowan PSF, Cummings D, Dixon CE, Ferguson AR, Ferland-Beckham C, Floyd C, Friess S, Galanopoulou A, Hall ED, Harris NG, ... ... Smith DH, et al. Preclinical Common Data Elements for Traumatic Brain Injury Research: Progress and Use Cases. Journal of Neurotrauma. PMID 33297844 DOI: 10.1089/neu.2020.7328  0.803
2020 ElSaadani M, Ahmed SM, Jacovides C, Lopez A, Johnson VE, Kaplan LJ, Schwab CW, Smith DH, Pascual JL. ANTITHROMBIN-III AMELIORATES POST-TBI CEREBRAL LEUKOCYTE MOBILIZATION ENHANCING RECOVERY OF BLOOD BRAIN BARRIER INTEGRITY. The Journal of Trauma and Acute Care Surgery. PMID 33093292 DOI: 10.1097/TA.0000000000003000  0.34
2020 Alisafaei F, Gong Z, Johnson VE, Dollé JP, Smith DH, Shenoy VB. Mechanisms of Local Stress Amplification in Axons near the Gray-White Matter Interface. Biophysical Journal. 119: 1290-1300. PMID 33027609 DOI: 10.1016/j.bpj.2020.08.024  0.41
2020 Mayer AR, Dodd AB, Ling JM, Stephenson DD, Rannou-Latella JG, Vermillion MS, Mehos CJ, Johnson VE, Gigliotti AP, Dodd RJ, Chaudry IH, Meier TB, Smith DH, Bragin DE, Lai C, et al. Survival Rates and Biomarkers in A Large Animal Model of Traumatic Brain Injury Combined with Two Different Levels of Blood Loss. Shock (Augusta, Ga.). PMID 32881755 DOI: 10.1097/Shk.0000000000001653  0.492
2020 Smith DH, Stewart W. 'Concussion' is not a true diagnosis. Nature Reviews. Neurology. PMID 32647140 DOI: 10.1038/S41582-020-0382-Y  0.401
2020 Katiyar KS, Struzyna LA, Morand JP, Burrell JC, Clements B, Laimo FA, Browne KD, Kohn J, Ali Z, Ledebur HC, Smith DH, Cullen DK. Tissue Engineered Axon Tracts Serve as Living Scaffolds to Accelerate Axonal Regeneration and Functional Recovery Following Peripheral Nerve Injury in Rats. Frontiers in Bioengineering and Biotechnology. 8: 492. PMID 32523945 DOI: 10.3389/Fbioe.2020.00492  0.807
2020 Burrell JC, Browne KD, Dutton JL, Laimo FA, Das S, Brown DP, Roberts S, Petrov D, Ali Z, Ledebur HC, Rosen JM, Kaplan HM, Wolf JA, Smith DH, Chen HI, et al. A Porcine Model of Peripheral Nerve Injury Enabling Ultra-Long Regenerative Distances: Surgical Approach, Recovery Kinetics, and Clinical Relevance. Neurosurgery. PMID 32392341 DOI: 10.1093/Neuros/Nyaa106  0.813
2020 Arena JD, Smith DH, Lee EB, Gibbons GS, Irwin DJ, Robinson JL, Lee VM, Trojanowski JQ, Stewart W, Johnson VE. Tau immunophenotypes in chronic traumatic encephalopathy recapitulate those of ageing and Alzheimer's disease. Brain : a Journal of Neurology. PMID 32390044 DOI: 10.1093/Brain/Awaa071  0.32
2020 Siman R, Cui H, Wewerka SS, Hamel L, Smith DH, Zwank MD. Serum SNTF, a Surrogate Marker of Axonal Injury, Is Prognostic for Lasting Brain Dysfunction in Mild TBI Treated in the Emergency Department. Frontiers in Neurology. 11: 249. PMID 32322237 DOI: 10.3389/Fneur.2020.00249  0.523
2020 Jgamadze D, Johnson VE, Wolf JA, Kacy Cullen D, Song H, Ming G, Smith DH, Isaac Chen H. Modeling traumatic brain injury with human brain organoids Current Opinion in Biomedical Engineering. 14: 52-58. DOI: 10.1016/J.Cobme.2020.05.004  0.669
2019 Ezra Sadik M, Ozturk AK, Albayar A, Branche M, Zadnik Sullivan P, Schlosser L, Dolle JP, Browne K, Jaye A, Smith DH. A Strategy Towards Bridging A Complete Spinal Cord Lesion Using Stretch-Grown Axons. Tissue Engineering. Part A. PMID 31852361 DOI: 10.1089/Ten.Tea.2019.0230  0.435
2019 Xu ZX, Albayar A, Dollé JP, Hansel G, Bianchini J, Sullivan PZ, Kacy Cullen D, Smith DH, Ozturk AK. Dorsal root ganglion axons facilitate and guide cortical neural outgrowth: In vitro modeling of spinal cord injury axonal regeneration. Restorative Neurology and Neuroscience. PMID 31594262 DOI: 10.3233/Rnn-190933  0.444
2019 Jacovides CL, Ahmed S, Suto Y, Paris AJ, Leone R, McCarry J, Christofidou-Solomidou M, Kaplan LJ, Smith DH, Holena DN, Schwab CW, Pascual JL. An Inflammatory Pulmonary Insult Post-TBI Worsens Subsequent Spatial Learning and Neurological Outcomes. The Journal of Trauma and Acute Care Surgery. PMID 31205212 DOI: 10.1097/Ta.0000000000002403  0.443
2019 Lee EB, Kinch K, Johnson VE, Trojanowski JQ, Smith DH, Stewart W. Chronic traumatic encephalopathy is a common co-morbidity, but less frequent primary dementia in former soccer and rugby players. Acta Neuropathologica. PMID 31152201 DOI: 10.1007/S00401-019-02030-Y  0.305
2019 Gan ZS, Stein SC, Swanson R, Guan S, Garcia L, Mehta D, Smith DH. Blood Biomarkers for Traumatic Brain Injury: A Quantitative Assessment of Diagnostic and Prognostic Accuracy. Frontiers in Neurology. 10: 446. PMID 31105646 DOI: 10.3389/Fneur.2019.00446  0.405
2019 Carteri RB, Kopczynski A, Rodolphi MS, Strogulski NR, Sartor M, Feldmann M, De Bastiani MA, Duval Wannmacher CM, Franceschini ID, Hansel G, Smith DH, Portela LVC. Testosterone administration after traumatic brain injury reduces mitochondrial dysfunction and neurodegeneration. Journal of Neurotrauma. PMID 30794079 DOI: 10.1089/Neu.2018.6266  0.459
2019 Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O'Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, ... ... Smith DH, et al. Primum non nocere: a call for balance when reporting on CTE. The Lancet. Neurology. 18: 231-233. PMID 30784550 DOI: 10.1016/S1474-4422(19)30020-1  0.635
2019 Albayar AA, Roche A, Swiatkowski P, Antar S, Ouda N, Emara E, Smith DH, Ozturk AK, Awad BI. Biomarkers in Spinal Cord Injury: Prognostic Insights and Future Potentials. Frontiers in Neurology. 10: 27. PMID 30761068 DOI: 10.3389/Fneur.2019.00027  0.416
2019 Smith DH, Johnson VE, Trojanowski JQ, Stewart W. Chronic traumatic encephalopathy - confusion and controversies. Nature Reviews. Neurology. PMID 30664683 DOI: 10.1038/S41582-018-0114-8  0.388
2019 Chen HI, Jgamadze D, Lim J, Mensah-Brown K, Wolf JA, Mills JA, Smith D. Functional cortical axon tracts generated from human stem cell-derived neurons. Tissue Engineering. Part A. PMID 30648482 DOI: 10.1089/Ten.Tea.2018.0270  0.659
2018 Su YS, Schuster JM, Smith DH, Stein SC. Cost Effectiveness of Biomarker Screening for Traumatic Brain Injury. Journal of Neurotrauma. PMID 30547708 DOI: 10.1089/Neu.2018.6020  0.336
2018 Ulyanova AV, Koch PF, Cottone C, Grovola MR, Adam CD, Browne KD, Weber MT, Russo RJ, Gagnon KG, Smith DH, Isaac Chen H, Johnson VE, Kacy Cullen D, Wolf JA. Electrophysiological Signature Reveals Laminar Structure of the Porcine Hippocampus. Eneuro. 5. PMID 30229132 DOI: 10.1523/ENEURO.0102-18.2018  0.505
2018 Smith DH, Stewart W. Traumatic brain injury: a platform for studies in Aβ processing: Commentary on: "Rapid Aβ oligomer and protofibril accumulation in traumatic brain injury". Brain Pathology (Zurich, Switzerland). 28: 463-465. PMID 30133864 DOI: 10.1111/Bpa.12534  0.487
2018 Zanier ER, Bertani I, Sammali E, Pischiutta F, Chiaravalloti MA, Vegliante G, Masone A, Corbelli A, Smith DH, Menon DK, Stocchetti N, Fiordaliso F, De Simoni MG, Stewart W, Chiesa R. Induction of a transmissible tau pathology by traumatic brain injury. Brain : a Journal of Neurology. PMID 30084913 DOI: 10.1093/Brain/Awy193  0.479
2018 Suto Y, Nagata K, Ahmed S, Jacovides C, Browne KD, Cognetti J, Johnson VE, Leone R, Kaplan LJ, Smith DH, Pascual JL. CEREBRAL EDEMA AND NEUROLOGICAL RECOVERY AFTER TRAUMATIC BRAIN INJURY IS WORSENED IF ACCOMPANIED BY A CONCOMITANT LONG BONE FRACTURE. Journal of Neurotrauma. PMID 30084745 DOI: 10.1089/Neu.2018.5812  0.355
2018 Knoll RM, Reinshagen KL, Barber SR, Ghanad I, Swanson R, Smith DH, Abdullah KG, Jung DH, Remenschneider AK, Kozin ED. Computed Tomography Atlas of the Porcine Temporal Bone and Skull Base: Anatomical Correlates for Traumatic Brain Injury Research. Journal of Neurotrauma. PMID 29969939 DOI: 10.1089/Neu.2018.5808  0.373
2018 Kovacs GG, Xie SX, Robinson JL, Lee EB, Smith DH, Schuck T, Lee VM, Trojanowski JQ. Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain. Acta Neuropathologica Communications. 6: 50. PMID 29891013 DOI: 10.1186/S40478-018-0552-Y  0.312
2018 Suto Y, Nagata K, Ahmed SM, Jacovides C, Browne KD, Cognetti J, Weber MT, Johnson VE, Leone R, Kaplan LJ, Smith DH, Pascual JL. A CONCOMITANT BONE FRACTURE DELAYS COGNITIVE RECOVERY FROM TRAUMATIC BRAIN INJURY. The Journal of Trauma and Acute Care Surgery. PMID 29787539 DOI: 10.1097/Ta.0000000000001957  0.422
2018 DeWitt D, Hawkins BE, Dixon CE, Kochanek PM, Armstead WM, Bass C', Bramlett HM, Büki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds Ii CSR, LaPlaca M, Long J, ... ... Smith DH, et al. Preclinical Testing of Therapies for Traumatic Brain Injury. Journal of Neurotrauma. PMID 29756522 DOI: 10.1089/Neu.2018.5778  0.75
2018 Johnson VE, Weber MT, Xiao R, Cullen DK, Meaney DF, Stewart W, Smith DH. Mechanical disruption of the blood-brain barrier following experimental concussion. Acta Neuropathologica. PMID 29460006 DOI: 10.1007/S00401-018-1824-0  0.667
2018 Nagata K, Suto Y, Cognetti J, Browne KD, Kumasaka K, Johnson VE, Kaplan L, Marks J, Smith DH, Pascual JL. Early Non-anticoagulant Desulfated Heparin After TBI: Reduced Brain Edema and Leukocyte Mobilization is Associated with Improved Watermaze Learning Ability Weeks After Injury. The Journal of Trauma and Acute Care Surgery. PMID 29373460 DOI: 10.1097/Ta.0000000000001819  0.46
2018 Ahmed S, Suto Y, Jacovides C, Nagata K, Cognetti J, Browne K, Weber M, Johnson V, Leone R, Kaplan L, Smith D, Pascual J. 834: DOACS AND ASA REDUCE BRAIN LEUKOCYTE RECRUITMENT AND EDEMA AFTER TBI AND MAY IMPROVE RECOVERY Critical Care Medicine. 46: 401-401. DOI: 10.1097/01.Ccm.0000528843.43625.52  0.411
2018 Jacovides CL, Ahmed SM, Suto Y, Kaplan LJ, Schwab CW, Smith DH, Sielecki T, Christofidou-Solomidou M, Pascual-Lopez JL. Synthetic Lignan Secoisolariciresinol Diglucoside Reduces Cerebral Leukocyte Mobilization after Traumatic Brain Injury Journal of the American College of Surgeons. 227: e64-e65. DOI: 10.1016/J.Jamcollsurg.2018.08.181  0.474
2018 Ahmed SM, Jacovides CL, Suto Y, Leone RM, Roche A, Weber MT, Johnson VE, Kaplan LJ, Smith DH, Pascual JL. Low-Anticoagulant Heparin Improves Outcomes after Traumatic Brain Injury: Balancing Inflammation Mitigation and Bleeding Potentiation Journal of the American College of Surgeons. 227: S267. DOI: 10.1016/J.Jamcollsurg.2018.07.551  0.451
2017 Dollé JP, Jaye A, Anderson SA, Ahmadzadeh H, Shenoy VB, Smith DH. Newfound sex differences in axonal structure underlie differential outcomes from in vitro traumatic axonal injury. Experimental Neurology. PMID 29104114 DOI: 10.1016/J.Expneurol.2017.11.001  0.451
2017 Cernak I, Stein DG, Elder GA, Ahlers S, Curley K, DePalma RG, Duda J, Ikonomovic M, Iverson GL, Kobeissy F, Koliatsos VE, Leggieri MJ, Pacifico AM, Smith DH, Swanson R, et al. Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions. Brain Injury. 31: 1168-1176. PMID 28981339 DOI: 10.1080/02699052.2016.1274779  0.437
2017 Agoston D, Arun P, Bellgowan P, Broglio S, Cantu R, Cook D, da Silva UO, Dickstein D, Elder G, Fudge E, Gandy S, Gill J, Glenn JF, Gupta RK, Hinds S, ... ... Smith D, et al. Military Blast Injury and Chronic Neurodegeneration: Research Presentations from the 2015 International State-of-the-Science Meeting. Journal of Neurotrauma. 34: S6-S17. PMID 28937955 DOI: 10.1089/Neu.2017.5220  0.427
2017 Johnson VE, Stewart W, Arena JD, Smith DH. Traumatic Brain Injury as a Trigger of Neurodegeneration. Advances in Neurobiology. 15: 383-400. PMID 28674990 DOI: 10.1007/978-3-319-57193-5_15  0.473
2017 Stefani MA, Modkovski R, Hansel G, Zimmer ER, Kopczynski A, Muller AP, Strogulski NR, Rodolphi MS, Carteri RK, Schmidt AP, Oses JP, Smith DH, Portela LV. Elevated glutamate and lactate predict brain death after severe head trauma. Annals of Clinical and Translational Neurology. 4: 392-402. PMID 28589166 DOI: 10.1002/Acn3.416  0.401
2017 Nagata K, Browne KD, Suto Y, Kumasaka K, Cognetti J, Johnson VE, Marks J, Smith DH, Pascual JL. Early Heparin Administration After TBI: Prolonged Cognitive Recovery Associated With Reduced Cerebral Edema and Neutrophil Sequestration. The Journal of Trauma and Acute Care Surgery. PMID 28538627 DOI: 10.1097/Ta.0000000000001590  0.444
2017 Wolf JA, Johnson BN, Johnson VE, Putt ME, Browne KD, Mietus CJ, Brown DP, Wofford KL, Smith DH, Grady MS, Cohen AS, Cullen DK. Concussion Induces Hippocampal Circuitry Disruption in Swine. Journal of Neurotrauma. PMID 28298170 DOI: 10.1089/neu.2016.4848  0.729
2017 Chen HI, Wolf J, Smith D. Multichannel activity propagation across an engineered axon network. Journal of Neural Engineering. PMID 28140365 DOI: 10.1088/1741-2552/Aa5Ccd  0.634
2016 Smith DH. Neuromechanics and Pathophysiology of Diffuse Axonal Injury in Concussion. Bridge (Washington, D.C. : 1969). 46: 79-84. PMID 28867874  0.377
2016 Purohit PK, Smith DH. A model for stretch growth of neurons. Journal of Biomechanics. PMID 27890538 DOI: 10.1016/J.Jbiomech.2016.11.045  0.385
2016 Cullen DK, Harris JP, Browne KD, Wolf JA, Duda JE, Meaney DF, Margulies SS, Smith DH. A Porcine Model of Traumatic Brain Injury via Head Rotational Acceleration. Methods in Molecular Biology (Clifton, N.J.). 1462: 289-324. PMID 27604725 DOI: 10.1007/978-1-4939-3816-2_17  0.731
2016 Nagata K, Kumasaka K, Browne KD, Li S, St-Pierre J, Cognetti J, Marks J, Johnson VE, Smith DH, Pascual JL. Unfractionated heparin after TBI reduces in vivo cerebrovascular inflammation, brain edema and accelerates cognitive recovery. The Journal of Trauma and Acute Care Surgery. PMID 27533909 DOI: 10.1097/Ta.0000000000001215  0.437
2016 Stewart W, Smith DH. Time to be blunt about blast traumatic brain injury. The Lancet. Neurology. PMID 27291519 DOI: 10.1016/S1474-4422(16)30058-8  0.484
2016 Chen HI, Jgamadze D, Serruya MD, Cullen DK, Wolf JA, Smith DH. Neural Substrate Expansion for the Restoration of Brain Function. Frontiers in Systems Neuroscience. 10: 1. PMID 26834579 DOI: 10.3389/Fnsys.2016.00001  0.697
2016 Hay J, Johnson VE, Smith DH, Stewart W. Chronic Traumatic Encephalopathy: The Neuropathological Legacy of Traumatic Brain Injury. Annual Review of Pathology. PMID 26772317 DOI: 10.1146/Annurev-Pathol-012615-044116  0.495
2016 Rabinowitz AR, Smith DH. Traumatic Brain Injury and Rationale for a Neuropsychological Diagnosis of Diffuse Axonal Injury Genes, Environment and Alzheimer's Disease. 267-293. DOI: 10.1016/B978-0-12-802851-3.00009-7  0.36
2015 Ali ZS, Johnson VE, Stewart W, Zager EL, Xiao R, Heuer GG, Weber MT, Mallela AN, Smith DH. Neuropathological Characteristics of Brachial Plexus Avulsion Injury With and Without Concomitant Spinal Cord Injury. Journal of Neuropathology and Experimental Neurology. PMID 26671984 DOI: 10.1093/Jnen/Nlv002  0.412
2015 Li S, Eisenstadt R, Kumasaka K, Johnson VE, Marks J, Nagata K, Browne KD, Smith DH, Pascual JL. Does enoxaparin interfere with HMGB1 signalling after TBI? A potential mechanism for reduced cerebral edema and neurologic recovery. The Journal of Trauma and Acute Care Surgery. PMID 26670109 DOI: 10.1097/Ta.0000000000000935  0.431
2015 Ahmadzadeh H, Smith DH, Shenoy VB. Mechanical Effects of Dynamic Binding between Tau Proteins on Microtubules during Axonal Injury. Biophysical Journal. 109: 2328-2337. PMID 26636944 DOI: 10.1016/J.Bpj.2015.09.010  0.4
2015 Johnson VE, Stewart W, Weber MT, Cullen DK, Siman R, Smith DH. SNTF immunostaining reveals previously undetected axonal pathology in traumatic brain injury. Acta Neuropathologica. PMID 26589592 DOI: 10.1007/S00401-015-1506-0  0.669
2015 Hay JR, Johnson VE, Young AM, Smith DH, Stewart W. Blood-Brain Barrier Disruption Is an Early Event That May Persist for Many Years After Traumatic Brain Injury in Humans. Journal of Neuropathology and Experimental Neurology. 74: 1147-1157. PMID 26574669 DOI: 10.1097/Nen.0000000000000261  0.477
2015 Struzyna LA, Wolf JA, Mietus CJ, Adewole DO, Chen HI, Smith D, Cullen DK. Rebuilding brain circuitry with living micro-tissue engineered neural networks. Tissue Engineering. Part A. PMID 26414439 DOI: 10.1089/ten.TEA.2014.0557  0.707
2015 Li S, Marks JA, Eisenstadt R, Kumasaka K, Samadi D, Johnson VE, Holena DN, Allen SR, Browne KD, Smith DH, Pascual JL. Enoxaparin ameliorates post-traumatic brain injury edema and neurologic recovery, reducing cerebral leukocyte endothelial interactions and vessel permeability in vivo. The Journal of Trauma and Acute Care Surgery. 79: 78-84. PMID 26091318 DOI: 10.1097/Ta.0000000000000697  0.471
2015 Smith DH, Hicks M, Johnson VE, Bergstrom D, Cummings D, Noble-Haeusslein L, Hovda D, Whalen M, Ahlers S, LaPlaca M, Tortella F, Duhaime AC, Dixon CE. Preclinical Traumatic Brain Injury Common Data Elements: Towards a Common Language Across Laboratories. Journal of Neurotrauma. PMID 26058402 DOI: 10.1089/Neu.2014.3861  0.658
2015 Johnson VE, Meaney DF, Cullen DK, Smith DH. Animal models of traumatic brain injury. Handbook of Clinical Neurology. 127: 115-28. PMID 25702213 DOI: 10.1016/B978-0-444-52892-6.00008-8  0.627
2015 Meaney DF, Smith DH. Cellular biomechanics of central nervous system injury. Handbook of Clinical Neurology. 127: 105-14. PMID 25702212 DOI: 10.1016/B978-0-444-52892-6.00007-6  0.431
2015 Siman R, Shahim P, Tegner Y, Blennow K, Zetterberg H, Smith DH. Serum SNTF Increases in Concussed Professional Ice Hockey Players and Relates to the Severity of Postconcussion Symptoms. Journal of Neurotrauma. PMID 25419578 DOI: 10.1089/Neu.2014.3698  0.423
2014 Kumasaka K, Marks JA, Eisenstadt R, Murcy MA, Samadi D, Li S, Johnson V, Browne KD, Smith DH, Schwab CW, Pascual JL. In vivo leukocyte-mediated brain microcirculatory inflammation: a comparison of osmotherapies and progesterone in severe traumatic brain injury. American Journal of Surgery. 208: 961-8; discussion 96. PMID 25305798 DOI: 10.1016/J.Amjsurg.2014.08.004  0.496
2014 Ahmadzadeh H, Smith DH, Shenoy VB. Viscoelasticity of tau proteins leads to strain rate-dependent breaking of microtubules during axonal stretch injury: predictions from a mathematical model. Biophysical Journal. 106: 1123-33. PMID 24606936 DOI: 10.1016/J.Bpj.2014.01.024  0.413
2014 Chen HI, Attiah M, Baltuch G, Smith DH, Hamilton RH, Lucas TH. Harnessing plasticity for the treatment of neurosurgical disorders: an overview. World Neurosurgery. 82: 648-59. PMID 24518888 DOI: 10.1016/J.Wneu.2014.02.003  0.385
2014 McCauley SR, Wilde EA, Barnes A, Hanten G, Hunter JV, Levin HS, Smith DH. Patterns of early emotional and neuropsychological sequelae after mild traumatic brain injury. Journal of Neurotrauma. 31: 914-25. PMID 24344952 DOI: 10.1089/Neu.2012.2826  0.352
2013 Siman R, Giovannone N, Hanten G, Wilde EA, McCauley SR, Hunter JV, Li X, Levin HS, Smith DH. Evidence That the Blood Biomarker SNTF Predicts Brain Imaging Changes and Persistent Cognitive Dysfunction in Mild TBI Patients. Frontiers in Neurology. 4: 190. PMID 24302918 DOI: 10.3389/Fneur.2013.00190  0.363
2013 Pascual JL, Murcy MA, Li S, Gong W, Eisenstadt R, Kumasaka K, Sims C, Smith DH, Browne K, Allen S, Baren J. Neuroprotective effects of progesterone in traumatic brain injury: blunted in vivo neutrophil activation at the blood-brain barrier. American Journal of Surgery. 206: 840-5; discussion 84. PMID 24112683 DOI: 10.1016/J.Amjsurg.2013.07.016  0.461
2013 Smith DH, Johnson VE, Stewart W. Chronic neuropathologies of single and repetitive TBI: substrates of dementia? Nature Reviews. Neurology. 9: 211-21. PMID 23458973 DOI: 10.1038/Nrneurol.2013.29  0.434
2013 Zetterberg H, Smith DH, Blennow K. Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood. Nature Reviews. Neurology. 9: 201-10. PMID 23399646 DOI: 10.1038/Nrneurol.2013.9  0.472
2013 Johnson VE, Stewart JE, Begbie FD, Trojanowski JQ, Smith DH, Stewart W. Inflammation and white matter degeneration persist for years after a single traumatic brain injury. Brain : a Journal of Neurology. 136: 28-42. PMID 23365092 DOI: 10.1093/Brain/Aws322  0.504
2013 Cullen DK, Smith DH. Bionic connections. Scientific American. 308: 52-7. PMID 23342452 DOI: 10.1038/scientificamerican0113-52  0.382
2013 Smith DH, Hicks R, Povlishock JT. Therapy development for diffuse axonal injury. Journal of Neurotrauma. 30: 307-23. PMID 23252624 DOI: 10.1089/Neu.2012.2825  0.735
2013 Levin H, Smith D. Traumatic brain injury: Networks and neuropathology The Lancet Neurology. 12: 15-16. PMID 23237894 DOI: 10.1016/S1474-4422(12)70300-9  0.453
2013 Hanten G, Li X, Ibarra A, Wilde EA, Barnes A, McCauley SR, McCarthy J, Hoxhaj S, Mendez D, Hunter JV, Levin HS, Smith DH. Updating memory after mild traumatic brain injury and orthopedic injuries. Journal of Neurotrauma. 30: 618-24. PMID 23227898 DOI: 10.1089/Neu.2012.2392  0.371
2013 Tong J, Liu W, Wang X, Han X, Hyrien O, Samadani U, Smith DH, Huang JH. Inhibition of Nogo-66 receptor 1 enhances recovery of cognitive function after traumatic brain injury in mice. Journal of Neurotrauma. 30: 247-58. PMID 22967270 DOI: 10.1089/Neu.2012.2493  0.457
2013 Johnson VE, Stewart W, Smith DH. Axonal pathology in traumatic brain injury. Experimental Neurology. 246: 35-43. PMID 22285252 DOI: 10.1016/J.Expneurol.2012.01.013  0.547
2012 Marks JA, Li S, Gong W, Sanati P, Eisenstadt R, Sims C, Smith DH, Reilly PM, Pascual JL. Similar effects of hypertonic saline and mannitol on the inflammation of the blood-brain barrier microcirculation after brain injury in a mouse model. The Journal of Trauma and Acute Care Surgery. 73: 351-7; discussion 35. PMID 22846939 DOI: 10.1097/Ta.0B013E3182592F76  0.389
2012 Ducheyne P, Mauck RL, Smith DH. Biomaterials in the repair of sports injuries. Nature Materials. 11: 652-4. PMID 22825010 DOI: 10.1038/Nmat3392  0.36
2012 Cullen DK, Tang-Schomer MD, Struzyna LA, Patel AR, Johnson VE, Wolf JA, Smith DH. Microtissue engineered constructs with living axons for targeted nervous system reconstruction. Tissue Engineering. Part A. 18: 2280-9. PMID 22702955 DOI: 10.1089/Ten.Tea.2011.0534  0.713
2012 Armstead WM, Riley J, Yarovoi S, Cines DB, Smith DH, Higazi AA. tPA-S481A prevents neurotoxicity of endogenous tPA in traumatic brain injury. Journal of Neurotrauma. 29: 1794-802. PMID 22435890 DOI: 10.1089/Neu.2012.2328  0.423
2012 von Reyn CR, Mott RE, Siman R, Smith DH, Meaney DF. Mechanisms of calpain mediated proteolysis of voltage gated sodium channel α-subunits following in vitro dynamic stretch injury. Journal of Neurochemistry. 121: 793-805. PMID 22428606 DOI: 10.1111/J.1471-4159.2012.07735.X  0.478
2012 Liu W, Ren Y, Bossert A, Wang X, Dayawansa S, Tong J, He X, Smith DH, Gelbard HA, Huang JH. Allotransplanted neurons used to repair peripheral nerve injury do not elicit overt immunogenicity. Plos One. 7: e31675. PMID 22347502 DOI: 10.1371/Journal.Pone.0031675  0.376
2012 Tang-Schomer MD, Johnson VE, Baas PW, Stewart W, Smith DH. Partial interruption of axonal transport due to microtubule breakage accounts for the formation of periodic varicosities after traumatic axonal injury. Experimental Neurology. 233: 364-72. PMID 22079153 DOI: 10.1016/J.Expneurol.2011.10.030  0.479
2012 Johnson VE, Stewart W, Smith DH. Widespread Ï„ and amyloid-β pathology many years after a single traumatic brain injury in humans. Brain Pathology (Zurich, Switzerland). 22: 142-9. PMID 21714827 DOI: 10.1111/J.1750-3639.2011.00513.X  0.446
2011 Johnson VE, Stewart W, Trojanowski JQ, Smith DH. Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans. Acta Neuropathologica. 122: 715-26. PMID 22101322 DOI: 10.1007/S00401-011-0909-9  0.428
2011 Cullen DK, Browne KD, Xu Y, Adeeb S, Wolf JA, McCarron RM, Yang S, Chavko M, Smith DH. Blast-induced color change in photonic crystals corresponds with brain pathology. Journal of Neurotrauma. 28: 2307-18. PMID 22082449 DOI: 10.1089/Neu.2011.1718  0.697
2011 Cullen DK, Wolf JA, Smith DH, Pfister BJ. Neural tissue engineering for neuroregeneration and biohybridized interface microsystems in vivo (Part 2). Critical Reviews in Biomedical Engineering. 39: 241-59. PMID 21967304 DOI: 10.1615/Critrevbiomedeng.V39.I3.40  0.783
2011 Browne KD, Chen XH, Meaney DF, Smith DH. Mild traumatic brain injury and diffuse axonal injury in swine. Journal of Neurotrauma. 28: 1747-55. PMID 21740133 DOI: 10.1089/Neu.2011.1913  0.535
2011 Han X, Tong J, Zhang J, Farahvar A, Wang E, Yang J, Samadani U, Smith DH, Huang JH. Imipramine treatment improves cognitive outcome associated with enhanced hippocampal neurogenesis after traumatic brain injury in mice. Journal of Neurotrauma. 28: 995-1007. PMID 21463148 DOI: 10.1089/Neu.2010.1563  0.479
2011 Meaney DF, Smith DH. Biomechanics of concussion. Clinics in Sports Medicine. 30: 19-31, vii. PMID 21074079 DOI: 10.1016/J.Csm.2010.08.009  0.466
2011 Cullen DK, Xu Y, Reneer DV, Browne KD, Geddes JW, Yang S, Smith DH. Color changing photonic crystals detect blast exposure. Neuroimage. 54: S37-44. PMID 21040795 DOI: 10.1016/J.Neuroimage.2010.10.076  0.539
2010 Haacke EM, Duhaime AC, Gean AD, Riedy G, Wintermark M, Mukherjee P, Brody DL, DeGraba T, Duncan TD, Elovic E, Hurley R, Latour L, Smirniotopoulos JG, Smith DH. Common data elements in radiologic imaging of traumatic brain injury. Journal of Magnetic Resonance Imaging : Jmri. 32: 516-43. PMID 20815050 DOI: 10.1002/Jmri.22259  0.362
2010 Monnerie H, Tang-Schomer MD, Iwata A, Smith DH, Kim HA, Le Roux PD. Dendritic alterations after dynamic axonal stretch injury in vitro. Experimental Neurology. 224: 415-23. PMID 20478308 DOI: 10.1016/J.Expneurol.2010.05.001  0.519
2010 Armstead WM, Ganguly K, Kiessling JW, Riley J, Chen XH, Smith DH, Stein SC, Higazi AA, Cines DB, Bdeir K, Zaitsev S, Muzykantov VR. Signaling, delivery and age as emerging issues in the benefit/risk ratio outcome of tPA For treatment of CNS ischemic disorders. Journal of Neurochemistry. 113: 303-12. PMID 20405577 DOI: 10.1111/J.1471-4159.2010.06613.X  0.309
2010 Johnson VE, Stewart W, Smith DH. Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease? Nature Reviews. Neuroscience. 11: 361-70. PMID 20216546 DOI: 10.1038/Nrn2808  0.454
2010 Tang-Schomer MD, Patel AR, Baas PW, Smith DH. Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly, and axon degeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1401-10. PMID 20019243 DOI: 10.1096/Fj.09-142844  0.435
2009 Pfister BJ, Chickola L, Smith DH. Head motions while riding roller coasters: implications for brain injury. The American Journal of Forensic Medicine and Pathology. 30: 339-45. PMID 19901817 DOI: 10.1097/Paf.0B013E318187E0C9  0.704
2009 von Reyn CR, Spaethling JM, Mesfin MN, Ma M, Neumar RW, Smith DH, Siman R, Meaney DF. Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10350-6. PMID 19692609 DOI: 10.1523/Jneurosci.2339-09.2009  0.392
2009 Smith DH. Stretch growth of integrated axon tracts: extremes and exploitations. Progress in Neurobiology. 89: 231-9. PMID 19664679 DOI: 10.1016/J.Pneurobio.2009.07.006  0.377
2009 Yuen TJ, Browne KD, Iwata A, Smith DH. Sodium channelopathy induced by mild axonal trauma worsens outcome after a repeat injury. Journal of Neuroscience Research. 87: 3620-5. PMID 19565655 DOI: 10.1002/Jnr.22161  0.516
2009 Armstead WM, Ganguly K, Kiessling JW, Chen XH, Smith DH, Higazi AA, Cines DB, Bdeir K, Zaitsev S, Muzykantov VR. Red blood cells-coupled tPA prevents impairment of cerebral vasodilatory responses and tissue injury in pediatric cerebral hypoxia/ischemia through inhibition of ERK MAPK activation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1463-74. PMID 19436314 DOI: 10.1038/Jcbfm.2009.61  0.331
2009 Chen YC, Smith DH, Meaney DF. In-vitro approaches for studying blast-induced traumatic brain injury. Journal of Neurotrauma. 26: 861-76. PMID 19397424 DOI: 10.1089/Neu.2008.0645  0.444
2009 Stein SC, Ganguly K, Belfield CM, Xu X, Swanson EW, Chen XH, Browne KD, Johnson VE, Smith DH, LeBold DG, Cines DB, Muzykantov VR, Muzykhantov VR. Erythrocyte-bound tissue plasminogen activator is neuroprotective in experimental traumatic brain injury. Journal of Neurotrauma. 26: 1585-92. PMID 19331516 DOI: 10.1089/neu.2008-0720  0.489
2009 Johnson VE, Stewart W, Graham DI, Stewart JE, Praestgaard AH, Smith DH. A neprilysin polymorphism and amyloid-beta plaques after traumatic brain injury. Journal of Neurotrauma. 26: 1197-202. PMID 19326964 DOI: 10.1089/neu.2008-0843  0.39
2009 Huang JH, Cullen DK, Browne KD, Groff R, Zhang J, Pfister BJ, Zager EL, Smith DH. Long-term survival and integration of transplanted engineered nervous tissue constructs promotes peripheral nerve regeneration. Tissue Engineering. Part A. 15: 1677-85. PMID 19231968 DOI: 10.1089/Ten.Tea.2008.0294  0.753
2009 Chen XH, Johnson VE, Uryu K, Trojanowski JQ, Smith DH. A lack of amyloid beta plaques despite persistent accumulation of amyloid beta in axons of long-term survivors of traumatic brain injury. Brain Pathology (Zurich, Switzerland). 19: 214-23. PMID 18492093 DOI: 10.1111/J.1750-3639.2008.00176.X  0.457
2008 Kameswaran N, Cullen DK, Pfister BJ, Ranalli NJ, Huang JH, Zager EL, Smith DH. A novel neuroprosthetic interface with the peripheral nervous system using artificially engineered axonal tracts. Neurological Research. 30: 1063-7. PMID 19079981 DOI: 10.1179/174313208X362541  0.782
2008 Cullen DK, R Patel A, Doorish JF, Smith DH, Pfister BJ. Developing a tissue-engineered neural-electrical relay using encapsulated neuronal constructs on conducting polymer fibers. Journal of Neural Engineering. 5: 374-84. PMID 18827311 DOI: 10.1088/1741-2560/5/4/002  0.695
2008 Zhang J, Groff RF, Chen XH, Browne KD, Huang J, Schwartz ED, Meaney DF, Johnson VE, Stein SC, Rojkjaer R, Smith DH. Hemostatic and neuroprotective effects of human recombinant activated factor VII therapy after traumatic brain injury in pigs. Experimental Neurology. 210: 645-55. PMID 18291370 DOI: 10.1016/J.Expneurol.2007.12.019  0.532
2008 Huang JH, Zager EL, Zhang J, Groff RF, Pfister BJ, Cohen AS, Grady MS, Maloney-Wilensky E, Smith DH. Harvested human neurons engineered as live nervous tissue constructs: implications for transplantation. Laboratory investigation. Journal of Neurosurgery. 108: 343-7. PMID 18240932 DOI: 10.3171/Jns/2008/108/2/0343  0.674
2007 Uryu K, Chen XH, Martinez D, Browne KD, Johnson VE, Graham DI, Lee VM, Trojanowski JQ, Smith DH. Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans. Experimental Neurology. 208: 185-92. PMID 17826768 DOI: 10.1016/J.Expneurol.2007.06.018  0.471
2007 Pfister BJ, Huang JH, Kameswaran N, Zager EL, Smith DH. Neural engineering to produce in vitro nerve constructs and neurointerface. Neurosurgery. 60: 137-41; discussion 1. PMID 17228262 DOI: 10.1227/01.Neu.0000249197.61280.1D  0.77
2007 James B, Neese S, Banz W, Meyers C, Hou Y, Tan A, Smith D, Clough R. Enantiomers of Z‐Bisdehydrodoisynolic Acid: Effects on Traumatic Brain Injury in Young Adult Male Rats The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A598-D  0.413
2007 Armstead WM, Chen XH, Smith DH. NOC/oFQ antagonist post injury treatment protects against cerebral circulatory collapse and histopathology after combined prolonged hypotension and brain injury Journal of Cerebral Blood Flow and Metabolism. 27: BO01-04.  0.381
2006 Armstead WM, Nassar T, Akkawi S, Smith DH, Chen XH, Cines DB, Higazi AA. Neutralizing the neurotoxic effects of exogenous and endogenous tPA. Nature Neuroscience. 9: 1150-5. PMID 16936723 DOI: 10.1038/Nn1757  0.365
2006 Stein SC, Browne KD, Chen XH, Smith DH, Graham DI. Thromboembolism and delayed cerebral ischemia after subarachnoid hemorrhage: an autopsy study. Neurosurgery. 59: 781-7; discussion 78. PMID 16915120 DOI: 10.1227/01.Neu.0000227519.27569.45  0.301
2006 Maxwell WL, MacKinnon MA, Smith DH, McIntosh TK, Graham DI. Thalamic nuclei after human blunt head injury. Journal of Neuropathology and Experimental Neurology. 65: 478-88. PMID 16772871 DOI: 10.1097/01.Jnen.0000229241.28619.75  0.572
2006 Browne KD, Iwata A, Putt ME, Smith DH. Chronic ibuprofen administration worsens cognitive outcome following traumatic brain injury in rats. Experimental Neurology. 201: 301-7. PMID 16764859 DOI: 10.1016/J.Expneurol.2006.04.008  0.451
2006 Pfister BJ, Bonislawski DP, Smith DH, Cohen AS. Stretch-grown axons retain the ability to transmit active electrical signals. Febs Letters. 580: 3525-31. PMID 16730003 DOI: 10.1016/J.Febslet.2006.05.030  0.687
2006 Iwata A, Browne KD, Pfister BJ, Gruner JA, Smith DH. Long-term survival and outgrowth of mechanically engineered nervous tissue constructs implanted into spinal cord lesions. Tissue Engineering. 12: 101-10. PMID 16499447 DOI: 10.1089/Ten.2006.12.101  0.688
2006 Pfister BJ, Iwata A, Taylor AG, Wolf JA, Meaney DF, Smith DH. Development of transplantable nervous tissue constructs comprised of stretch-grown axons. Journal of Neuroscience Methods. 153: 95-103. PMID 16337007 DOI: 10.1016/J.Jneumeth.2005.10.012  0.767
2006 Jette N, Coderre E, Nikolaeva MA, Enright PD, Iwata A, Smith DH, Jiang Q, Stys PK. Spatiotemporal distribution of spectrin breakdown products induced by anoxia in adult rat optic nerve in vitro. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 777-86. PMID 16163297 DOI: 10.1038/Sj.Jcbfm.9600226  0.389
2006 Ganguly K, Stein SC, Groff RF, Zhang J, Smith DH, Cines DB, Muzykantov VR. Erythrocyte Coupled tPA Improves Outcomes of Percussion Brain Trauma in Rats. Blood. 108: 897-897. DOI: 10.1182/Blood.V108.11.897.897  0.446
2005 Iwata A, Browne KD, Chen XH, Yuguchi T, Smith DH. Traumatic brain injury induces biphasic upregulation of ApoE and ApoJ protein in rats. Journal of Neuroscience Research. 82: 103-14. PMID 16118797 DOI: 10.1002/Jnr.20607  0.479
2005 Stein SC, Graham DI, Chen XH, Dunn L, Smith DH. Apo E genotype not associated with intravascular coagulation in traumatic brain injury. Neuroscience Letters. 387: 28-31. PMID 16084020 DOI: 10.1016/J.Neulet.2005.07.011  0.431
2004 Stein SC, Smith DH. Coagulopathy in traumatic brain injury. Neurocritical Care. 1: 479-88. PMID 16174954 DOI: 10.1385/Ncc:1:4:479  0.473
2004 Lusardi TA, Rangan J, Sun D, Smith DH, Meaney DF. A device to study the initiation and propagation of calcium transients in cultured neurons after mechanical stretch. Annals of Biomedical Engineering. 32: 1546-58. PMID 15636114 DOI: 10.1114/B:Abme.0000049038.75368.75  0.362
2004 Maxwell WL, Pennington K, MacKinnon MA, Smith DH, McIntosh TK, Wilson JT, Graham DI. Differential responses in three thalamic nuclei in moderately disabled, severely disabled and vegetative patients after blunt head injury. Brain : a Journal of Neurology. 127: 2470-8. PMID 15456707 DOI: 10.1093/Brain/Awh294  0.563
2004 Pfister BJ, Iwata A, Meaney DF, Smith DH. Extreme stretch growth of integrated axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7978-83. PMID 15356212 DOI: 10.1523/Jneurosci.1974-04.2004  0.692
2004 Browne KD, Leoni MJ, Iwata A, Chen XH, Smith DH. Acute treatment with MgSO4 attenuates long-term hippocampal tissue loss after brain trauma in the rat. Journal of Neuroscience Research. 77: 878-83. PMID 15334605 DOI: 10.1002/Jnr.20215  0.469
2004 Chen XH, Siman R, Iwata A, Meaney DF, Trojanowski JQ, Smith DH. Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma. The American Journal of Pathology. 165: 357-71. PMID 15277212 DOI: 10.1016/S0002-9440(10)63303-2  0.459
2004 Iwata A, Stys PK, Wolf JA, Chen XH, Taylor AG, Meaney DF, Smith DH. Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4605-13. PMID 15140932 DOI: 10.1523/Jneurosci.0515-03.2004  0.653
2004 Stein SC, Graham DI, Chen XH, Smith DH. Association between intravascular microthrombosis and cerebral ischemia in traumatic brain injury. Neurosurgery. 54: 687-91; discussion 6. PMID 15028145 DOI: 10.1227/01.Neu.0000108641.98845.88  0.48
2004 Lusardi TA, Wolf JA, Putt ME, Smith DH, Meaney DF. Effect of acute calcium influx after mechanical stretch injury in vitro on the viability of hippocampal neurons. Journal of Neurotrauma. 21: 61-72. PMID 14987466 DOI: 10.1089/089771504772695959  0.591
2004 Chen X, Graham DI, Uryu K, Trojanowski JQ, Smith DH. P3-370 Long-term accumulations of amyloid-β in axons without prolonged amyloid plaque formation after brain trauma in humans Neurobiology of Aging. 25: S460. DOI: 10.1016/S0197-4580(04)81519-7  0.391
2004 Uryu K, Chen X, Graham DI, Martinez D, Smith DH, Trojanowski JQ. P2-250 Short-term accumulation of beta amyloid in axonal pathology following traumatic brain injury in human Neurobiology of Aging. 25: S303. DOI: 10.1016/S0197-4580(04)80996-5  0.491
2003 Smith DH, Meaney DF, Shull WH. Diffuse axonal injury in head trauma. The Journal of Head Trauma Rehabilitation. 18: 307-16. PMID 16222127 DOI: 10.1097/00001199-200307000-00003  0.52
2003 Smith DH, Uryu K, Saatman KE, Trojanowski JQ, McIntosh TK. Protein accumulation in traumatic brain injury. Neuromolecular Medicine. 4: 59-72. PMID 14528053 DOI: 10.1385/Nmm:4:1-2:59  0.756
2003 Chen XH, Iwata A, Nonaka M, Browne KD, Smith DH. Neurogenesis and glial proliferation persist for at least one year in the subventricular zone following brain trauma in rats. Journal of Neurotrauma. 20: 623-31. PMID 12908924 DOI: 10.1089/089771503322144545  0.48
2003 Smith DH, Chen XH, Iwata A, Graham DI. Amyloid beta accumulation in axons after traumatic brain injury in humans. Journal of Neurosurgery. 98: 1072-7. PMID 12744368 DOI: 10.3171/Jns.2003.98.5.1072  0.447
2003 Maxwell WL, Dhillon K, Harper L, Espin J, MacIntosh TK, Smith DH, Graham DI. There is differential loss of pyramidal cells from the human hippocampus with survival after blunt head injury. Journal of Neuropathology and Experimental Neurology. 62: 272-9. PMID 12638731 DOI: 10.1093/Jnen/62.3.272  0.345
2003 Saatman KE, Abai B, Grosvenor A, Vorwerk CK, Smith DH, Meaney DF. Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 34-42. PMID 12500089 DOI: 10.1097/01.Wcb.0000035040.10031.B0  0.704
2003 Lusardi TA, Smith DH, Wolf JA, Meaney DF. The separate roles of calcium and mechanical forces in mediating cell death in mechanically injured neurons. Biorheology. 40: 401-9. PMID 12454433  0.515
2002 Stein SC, Chen XH, Sinson GP, Smith DH. Intravascular coagulation: a major secondary insult in nonfatal traumatic brain injury. Journal of Neurosurgery. 97: 1373-7. PMID 12507136 DOI: 10.3171/Jns.2002.97.6.1373  0.439
2002 Iwata A, Chen XH, McIntosh TK, Browne KD, Smith DH. Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes. Journal of Neuropathology and Experimental Neurology. 61: 1056-68. PMID 12484568 DOI: 10.1093/Jnen/61.12.1056  0.65
2002 Smith DH, Meaney DF. Roller coasters, g forces, and brain trauma: on the wrong track? Journal of Neurotrauma. 19: 1117-20. PMID 12427321 DOI: 10.1089/08977150260337921  0.385
2001 Meaney DF, Margulies SS, Smith DH. Diffuse axonal injury. Journal of Neurosurgery. 95: 1108-10. PMID 11765833  0.353
2001 Smith DH, Wolf JA, Meaney DF. A new strategy to produce sustained growth of central nervous system axons: continuous mechanical tension. Tissue Engineering. 7: 131-9. PMID 11304449 DOI: 10.1089/107632701300062714  0.639
2001 Wolf JA, Stys PK, Lusardi T, Meaney D, Smith DH. Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1923-30. PMID 11245677 DOI: 10.1523/Jneurosci.21-06-01923.2001  0.629
2001 Smith DH, Wolf JA, Meaney DF. Tissue engineering of CNS axonal tracts using mechanically induced growth American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 413-414.  0.566
2001 Lusardi TA, Smith DH, Wolf JA, DeRidder MN, Meaney DF. Mechanical stretch of cultured neurons: Relationships between acute cytosolic calcium changes and cell death American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 615-616.  0.484
2000 Leoni MJ, Chen XH, Mueller AL, Cheney J, McIntosh TK, Smith DH. NPS 1506 attenuates cognitive dysfunction and hippocampal neuron death following brain trauma in the rat. Experimental Neurology. 166: 442-9. PMID 11085909 DOI: 10.1006/Exnr.2000.7513  0.567
2000 Smith DH, Nonaka M, Miller R, Leoni M, Chen XH, Alsop D, Meaney DF. Immediate coma following inertial brain injury dependent on axonal damage in the brainstem. Journal of Neurosurgery. 93: 315-22. PMID 10930019 DOI: 10.3171/Jns.2000.93.2.0315  0.528
2000 Nakagawa Y, Reed L, Nakamura M, McIntosh TK, Smith DH, Saatman KE, Raghupathi R, Clemens J, Saido TC, Lee VM, Trojanowski JQ. Brain trauma in aged transgenic mice induces regression of established abeta deposits. Experimental Neurology. 163: 244-52. PMID 10785464 DOI: 10.1006/Exnr.2000.7375  0.77
2000 Smith DH, Meaney DF. Axonal damage in traumatic brain injury Neuroscientist. 6: 483-495. DOI: 10.1177/107385840000600611  0.496
1999 Nonaka M, Chen XH, Pierce JE, Leoni MJ, McIntosh TK, Wolf JA, Smith DH. Prolonged activation of NF-kappaB following traumatic brain injury in rats. Journal of Neurotrauma. 16: 1023-34. PMID 10595819 DOI: 10.1089/Neu.1999.16.1023  0.704
1999 Smith DH, Chen XH, Nonaka M, Trojanowski JQ, Lee VM, Saatman KE, Leoni MJ, Xu BN, Wolf JA, Meaney DF. Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig. Journal of Neuropathology and Experimental Neurology. 58: 982-92. PMID 10499440  0.744
1999 Nakagawa Y, Nakamura M, McIntosh TK, Rodriguez A, Berlin JA, Smith DH, Saatman KE, Raghupathi R, Clemens J, Saido TC, Schmidt ML, Lee VM, Trojanowski JQ. Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging. The Journal of Comparative Neurology. 411: 390-8. PMID 10413774 DOI: 10.1002/(Sici)1096-9861(19990830)411:3<390::Aid-Cne3>3.0.Co;2-#  0.761
1999 Chen XH, Meaney DF, Xu BN, Nonaka M, McIntosh TK, Wolf JA, Saatman KE, Smith DH. Evolution of neurofilament subtype accumulation in axons following diffuse brain injury in the pig. Journal of Neuropathology and Experimental Neurology. 58: 588-96. PMID 10374749 DOI: 10.1097/00005072-199906000-00003  0.793
1999 Smith DH, Wolf JA, Lusardi TA, Lee VM, Meaney DF. High tolerance and delayed elastic response of cultured axons to dynamic stretch injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4263-9. PMID 10341230 DOI: 10.1523/Jneurosci.19-11-04263.1999  0.707
1999 McGowan JC, McCormack TM, Grossman RI, Mendonça R, Chen XH, Berlin JA, Meaney DF, Xu BN, Cecil KM, McIntosh TK, Smith DH. Diffuse axonal pathology detected with magnetization transfer imaging following brain injury in the pig. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 41: 727-33. PMID 10332848 DOI: 10.1002/(Sici)1522-2594(199904)41:4<727::Aid-Mrm11>3.0.Co;2-6  0.589
1999 Shreiber DI, Bain AC, Ross DT, Smith DH, Gennarelli TA, McIntosh TK, Meaney DF. Experimental investigation of cerebral contusion: histopathological and immunohistochemical evaluation of dynamic cortical deformation. Journal of Neuropathology and Experimental Neurology. 58: 153-64. PMID 10029098 DOI: 10.1097/00005072-199902000-00005  0.668
1999 Shreiber DI, Smith DH, Meaney DF. Immediate in vivo response of the cortex and the blood-brain barrier following dynamic cortical deformation in the rat. Neuroscience Letters. 259: 5-8. PMID 10027542 DOI: 10.1016/S0304-3940(98)00853-2  0.489
1999 Miller RT, Smith DH, Chen X, Xu BN, Leoni M, Nonaka M, Meaney DF. Comparing experimental data to traumatic brain injury finite element models Stapp Car Crash Conference Proceedings. 303-311. DOI: 10.4271/99Sc20  0.407
1999 Meaney DF, Ewoterai I, Wolf JA, Lusardi TG, Smith DH. Mechanical recovery of cultured axons after dynamic stretch: correlation to cytoskeletal changes American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 44: 45-49.  0.543
1998 McIntosh TK, Saatman KE, Raghupathi R, Graham DI, Smith DH, Lee VM, Trojanowski JQ. The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms. Neuropathology and Applied Neurobiology. 24: 251-67. PMID 9775390 DOI: 10.1046/J.1365-2990.1998.00121.X  0.798
1998 Smith DH, Cecil KM, Meaney DF, Chen XH, McIntosh TK, Gennarelli TA, Lenkinski RE. Magnetic resonance spectroscopy of diffuse brain trauma in the pig. Journal of Neurotrauma. 15: 665-74. PMID 9753214 DOI: 10.1089/Neu.1998.15.665  0.641
1998 Pierce JE, Smith DH, Trojanowski JQ, McIntosh TK. Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats. Neuroscience. 87: 359-69. PMID 9740398 DOI: 10.1016/S0306-4522(98)00142-0  0.669
1998 Smith DH, Nakamura M, McIntosh TK, Wang J, Rodríguez A, Chen XH, Raghupathi R, Saatman KE, Clemens J, Schmidt ML, Lee VM, Trojanowski JQ. Brain trauma induces massive hippocampal neuron death linked to a surge in beta-amyloid levels in mice overexpressing mutant amyloid precursor protein. The American Journal of Pathology. 153: 1005-10. PMID 9736050 DOI: 10.1016/S0002-9440(10)65643-X  0.774
1998 Okiyama K, Smith DH, White WF, McIntosh TK. Effects of the NMDA antagonist CP-98,113 on regional cerebral edema and cardiovascular, cognitive, and neurobehavioral function following experimental brain injury in the rat. Brain Research. 792: 291-8. PMID 9593949 DOI: 10.1016/S0006-8993(98)00158-9  0.589
1998 Zhang C, Raghupathi R, Saatman KE, Smith DH, Stutzmann JM, Wahl F, McIntosh TK. Riluzole attenuates cortical lesion size, but not hippocampal neuronal loss, following traumatic brain injury in the rat. Journal of Neuroscience Research. 52: 342-9. PMID 9590442 DOI: 10.1002/(Sici)1097-4547(19980501)52:3<342::Aid-Jnr10>3.0.Co;2-8  0.808
1998 Cecil KM, Hills EC, Sandel ME, Smith DH, McIntosh TK, Mannon LJ, Sinson GP, Bagley LJ, Grossman RI, Lenkinski RE. Proton magnetic resonance spectroscopy for detection of axonal injury in the splenium of the corpus callosum of brain-injured patients. Journal of Neurosurgery. 88: 795-801. PMID 9576245 DOI: 10.3171/Jns.1998.88.5.0795  0.662
1998 Cecil KM, Lenkinski RE, Meaney DF, McIntosh TK, Smith DH. High-field proton magnetic resonance spectroscopy of a swine model for axonal injury. Journal of Neurochemistry. 70: 2038-44. PMID 9572290 DOI: 10.1046/J.1471-4159.1998.70052038.X  0.657
1998 Murai H, Pierce JE, Raghupathi R, Smith DH, Saatman KE, Trojanowski JQ, Lee VM, Loring JF, Eckman C, Younkin S, McIntosh TK. Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury. The Journal of Comparative Neurology. 392: 428-38. PMID 9514508 DOI: 10.1002/(Sici)1096-9861(19980323)392:4<428::Aid-Cne2>3.0.Co;2-2  0.784
1998 Miller RT, Margulies SS, Leoni M, Nonaka M, Chen X, Smith DH, Meaney DF. Finite element modeling approaches for predicting injury in an experimental model of severe diffuse axonal injury Sae Technical Papers. DOI: 10.4271/983154  0.432
1997 Smith DH, Chen XH, Pierce JE, Wolf JA, Trojanowski JQ, Graham DI, McIntosh TK. Progressive atrophy and neuron death for one year following brain trauma in the rat. Journal of Neurotrauma. 14: 715-27. PMID 9383090 DOI: 10.1089/Neu.1997.14.715  0.762
1997 Saatman KE, Contreras PC, Smith DH, Raghupathi R, McDermott KL, Fernandez SC, Sanderson KL, Voddi M, McIntosh TK. Insulin-like growth factor-1 (IGF-1) improves both neurological motor and cognitive outcome following experimental brain injury. Experimental Neurology. 147: 418-27. PMID 9344566 DOI: 10.1006/Exnr.1997.6629  0.788
1997 Smith DH, Perri BR, Raghupathi R, Saatman KE, McIntosh TK. Remacemide hydrochloride reduces cortical lesion volume following brain trauma in the rat. Neuroscience Letters. 231: 135-8. PMID 9300640 DOI: 10.1016/S0304-3940(97)00551-X  0.772
1997 Rubin Y, Cecil K, Wehrli S, McIntosh TK, Lenkinski RE, Smith DH. High-resolution 1H NMR spectroscopy following experimental brain trauma. Journal of Neurotrauma. 14: 441-9. PMID 9257662 DOI: 10.1089/Neu.1997.14.441  0.639
1997 McIntosh TK, Garde E, Saatman KE, Smith DH. Central nervous system resuscitation. Emergency Medicine Clinics of North America. 15: 527-50. PMID 9255131 DOI: 10.1016/S0733-8627(05)70316-3  0.74
1997 Smith DH, Chen XH, Xu BN, McIntosh TK, Gennarelli TA, Meaney DF. Characterization of diffuse axonal pathology and selective hippocampal damage following inertial brain trauma in the pig. Journal of Neuropathology and Experimental Neurology. 56: 822-34. PMID 9210879 DOI: 10.1097/00005072-199756070-00009  0.686
1997 Okiyama K, Smith DH, White WF, Richter K, McIntosh TK. Effects of the novel NMDA antagonists CP-98,113, CP-101,581 and CP-101,606 on cognitive function and regional cerebral edema following experimental brain injury in the rat. Journal of Neurotrauma. 14: 211-22. PMID 9151770 DOI: 10.1089/Neu.1997.14.211  0.595
1997 McDermott KL, Raghupathi R, Fernandez SC, Saatman KE, Protter AA, Finklestein SP, Sinson G, Smith DH, McIntosh TK. Delayed administration of basic fibroblast growth factor (bFGF) attenuates cognitive dysfunction following parasagittal fluid percussion brain injury in the rat. Journal of Neurotrauma. 14: 191-200. PMID 9151768 DOI: 10.1089/Neu.1997.14.191  0.811
1997 Perri BR, Smith DH, Murai H, Sinson G, Saatman KE, Raghupathi R, Bartus RT, McIntosh TK. Metabolic quantification of lesion volume following experimental traumatic brain injury in the rat. Journal of Neurotrauma. 14: 15-22. PMID 9048307 DOI: 10.1089/Neu.1997.14.15  0.81
1996 McIntosh TK, Smith DH, Voddi M, Perri BR, Stutzmann JM. Riluzole, a novel neuroprotective agent, attenuates both neurologic motor and cognitive dysfunction following experimental brain injury in the rat. Journal of Neurotrauma. 13: 767-80. PMID 9002062 DOI: 10.1089/Neu.1996.13.767  0.615
1996 Fan L, Young PR, Barone FC, Feuerstein GZ, Smith DH, McIntosh TK. Experimental brain injury induces differential expression of tumor necrosis factor-alpha mRNA in the CNS. Brain Research. Molecular Brain Research. 36: 287-91. PMID 8965649 DOI: 10.1016/0169-328X(95)00274-V  0.583
1996 Alsop DC, Murai H, Detre JA, McIntosh TK, Smith DH. Detection of acute pathologic changes following experimental traumatic brain injury using diffusion-weighted magnetic resonance imaging. Journal of Neurotrauma. 13: 515-21. PMID 8913968 DOI: 10.1089/Neu.1996.13.515  0.636
1996 Hicks R, Soares H, Smith D, McIntosh T. Temporal and spatial characterization of neuronal injury following lateral fluid-percussion brain injury in the rat Acta Neuropathologica. 91: 236-246. PMID 8834535 DOI: 10.1007/S004010050421  0.831
1996 McIntosh TK, Smith DH, Garde E. Therapeutic approaches for the prevention of secondary brain injury. European Journal of Anaesthesiology. 13: 291-309. PMID 8737120 DOI: 10.1046/J.1365-2346.1996.00981.X  0.657
1996 Kimura H, Meaney DF, McGowan JC, Grossman RI, Lenkinski RE, Ross DT, McIntosh TK, Gennarelli TA, Smith DH. Magnetization transfer imaging of diffuse axonal injury following experimental brain injury in the pig: characterization by magnetization transfer ratio with histopathologic correlation. Journal of Computer Assisted Tomography. 20: 540-6. PMID 8708052 DOI: 10.1097/00004728-199607000-00007  0.666
1996 Saatman KE, Murai H, Bartus RT, Smith DH, Hayward NJ, Perri BR, McIntosh TK. Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat. Proceedings of the National Academy of Sciences of the United States of America. 93: 3428-33. PMID 8622952 DOI: 10.1073/Pnas.93.8.3428  0.725
1996 Pierce JE, Trojanowski JQ, Graham DI, Smith DH, McIntosh TK. Immunohistochemical characterization of alterations in the distribution of amyloid precursor proteins and beta-amyloid peptide after experimental brain injury in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 1083-90. PMID 8558237 DOI: 10.1523/Jneurosci.16-03-01083.1996  0.668
1996 Smith D, Meaney D, Lenkinski R. New magnetic resonance imaging techniques for the evaluation of traumatic brain injury Journal of Head Trauma Rehabilitation. 11: 100-101. DOI: 10.1097/00001199-199612000-00015  0.392
1995 Raghupathi R, McIntosh TK, Smith DH. Cellular responses to experimental brain injury. Brain Pathology (Zurich, Switzerland). 5: 437-42. PMID 8974626 DOI: 10.1111/J.1750-3639.1995.Tb00622.X  0.735
1995 Meaney DF, Smith DH, Shreiber DI, Bain AC, Miller RT, Ross DT, Gennarelli TA. Biomechanical analysis of experimental diffuse axonal injury. Journal of Neurotrauma. 12: 689-94. PMID 8683620 DOI: 10.1089/Neu.1995.12.689  0.534
1995 Smith DH, Meaney DF, Lenkinski RE, Alsop DC, Grossman R, Kimura H, McIntosh TK, Gennarelli TA. New magnetic resonance imaging techniques for the evaluation of traumatic brain injury. Journal of Neurotrauma. 12: 573-7. PMID 8683608 DOI: 10.1089/Neu.1995.12.573  0.606
1995 Rubin Y, LaPlaca MC, Smith DH, Thibault LE, Lenkinski RE. The effect of N-acetylaspartate on the intracellular free calcium concentration in NTera2-neurons. Neuroscience Letters. 198: 209-12. PMID 8552323 DOI: 10.1016/0304-3940(95)12014-U  0.569
1995 Okiyama K, Smith DH, Gennarelli TA, Simon RP, Leach M, McIntosh TK. The sodium channel blocker and glutamate release inhibitor BW1003C87 and magnesium attenuate regional cerebral edema following experimental brain injury in the rat. Journal of Neurochemistry. 64: 802-9. PMID 7830074 DOI: 10.1046/J.1471-4159.1995.64020802.X  0.651
1995 Smith DH, Soares HD, Pierce JS, Perlman KG, Saatman KE, Meaney DF, Dixon CE, McIntosh TK. A model of parasagittal controlled cortical impact in the mouse: cognitive and histopathologic effects. Journal of Neurotrauma. 12: 169-78. PMID 7629863 DOI: 10.1089/Neu.1995.12.169  0.832
1995 Hicks RR, Smith DH, McIntosh TK. Temporal response and effects of excitatory amino acid antagonism on microtubule-associated protein 2 immunoreactivity following experimental brain injury in rats. Brain Research. 678: 151-60. PMID 7620884 DOI: 10.1016/0006-8993(95)00179-T  0.765
1995 Fan L, Young PR, Barone FC, Feuerstein GZ, Smith DH, McIntosh TK. Experimental brain injury induces expression of interleukin-1 beta mRNA in the rat brain. Brain Research. Molecular Brain Research. 30: 125-30. PMID 7609633 DOI: 10.1016/0169-328X(94)00287-O  0.613
1995 Smith DH, Gennarelli TA, McIntosh TK. The Potential of 21-Aminosteroids (Lazaroids) as Neuroprotective Therapies in CNS Injury Cns Drugs. 3: 159-164. DOI: 10.2165/00023210-199503030-00001  0.572
1995 Soares H, Hicks R, Smith D, McIntosh T. Inflammatory leukocytic recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury The Journal of Neuroscience. 15: 8223-8233. DOI: 10.1523/Jneurosci.15-12-08223.1995  0.478
1995 Okiyama K, Smith DH, Gennarelli TA, Simon RP, Leach M, Mclntosh TK. The sodium channel blocker and glutamate release inhibitor BW1003C87 and magnesium attenuate regional cerebral edema following experimental brain injury in the rat Journal of Neurosurgical Anesthesiology. 7: 198. DOI: 10.1097/00008506-199507000-00011  0.397
1994 Okiyama K, Rosenkrantz TS, Smith DH, Gennarelli TA, McIntosh TK. (S)-emopamil attenuates acute reduction in regional cerebral blood flow following experimental brain injury. Journal of Neurotrauma. 11: 83-95. PMID 8201628 DOI: 10.1089/Neu.1994.11.83  0.635
1994 Smith DH, Lowenstein DH, Gennarelli TA, McIntosh TK. Persistent memory dysfunction is associated with bilateral hippocampal damage following experimental brain injury. Neuroscience Letters. 168: 151-4. PMID 8028769 DOI: 10.1016/0304-3940(94)90438-3  0.609
1994 Ross DT, Meaney DF, Sabol MK, Smith DH, Gennarelli TA. Distribution of forebrain diffuse axonal injury following inertial closed head injury in miniature swine. Experimental Neurology. 126: 291-9. PMID 7925827 DOI: 10.1006/Exnr.1994.1067  0.528
1994 Hicks RR, Smith DH, Gennarelli TA, McIntosh T. Kynurenate is neuroprotective following experimental brain injury in the rat. Brain Research. 655: 91-6. PMID 7812795 DOI: 10.1016/0006-8993(94)91601-2  0.784
1993 Smith DH, Okiyama K, Thomas MJ, McIntosh TK. Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 5383-92. PMID 8254381 DOI: 10.1523/Jneurosci.13-12-05383.1993  0.602
1993 Pierce JE, Smith DH, Eison MS, McIntosh TK. The nootropic compound BMY-21502 improves spatial learning ability in brain injured rats. Brain Research. 624: 199-208. PMID 8252392 DOI: 10.1016/0006-8993(93)90078-2  0.629
1993 Smith DH, Okiyama K, Gennarelli TA, McIntosh TK. Magnesium and ketamine attenuate cognitive dysfunction following experimental brain injury. Neuroscience Letters. 157: 211-4. PMID 8233056 DOI: 10.1016/0304-3940(93)90739-8  0.593
1993 Hicks RR, Smith DH, Lowenstein DH, Saint Marie R, McIntosh TK. Mild experimental brain injury in the rat induces cognitive deficits associated with regional neuronal loss in the hippocampus. Journal of Neurotrauma. 10: 405-14. PMID 8145264 DOI: 10.1089/Neu.1993.10.405  0.771
1992 McIntosh TK, Thomas M, Smith D, Banbury M. The novel 21-aminosteroid U74006F attenuates cerebral edema and improves survival after brain injury in the rat. Journal of Neurotrauma. 9: 33-46. PMID 1619674 DOI: 10.1089/Neu.1992.9.33  0.644
1992 Okiyama K, Smith DH, Thomas MJ, McIntosh TK. Evaluation of a novel calcium channel blocker, (S)-emopamil, on regional cerebral edema and neurobehavioral function after experimental brain injury. Journal of Neurosurgery. 77: 607-15. PMID 1527621 DOI: 10.3171/Jns.1992.77.4.0607  0.642
1992 Prasad MR, Tzigaret CM, Smith D, Soares H, McIntosh TK. Decreased alpha 1-adrenergic receptors after experimental brain injury. Journal of Neurotrauma. 9: 269-79. PMID 1335519 DOI: 10.1089/Neu.1992.9.269  0.764
1992 Lowenstein DH, Thomas MJ, Smith DH, McIntosh TK. Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head trauma and disorders of the hippocampus The Journal of Neuroscience. 12: 4846-4853. DOI: 10.1523/Jneurosci.12-12-04846.1992  0.462
1991 Smith DH, Okiyama K, Thomas MJ, Claussen B, McIntosh TK. Evaluation of memory dysfunction following experimental brain injury using the Morris water maze. Journal of Neurotrauma. 8: 259-69. PMID 1803034 DOI: 10.1089/Neu.1991.8.259  0.633
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