Patrick Hearing - Publications

Stony Brook University, Stony Brook, NY, United States 
Genetics, Molecular Biology, Microbiology Biology

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Avgousti DC, Herrmann C, Kulej K, Pancholi NJ, Sekulic N, Petrescu J, Molden RC, Blumenthal D, Paris AJ, Reyes ED, Ostapchuk P, Hearing P, Seeholzer SH, Worthen GS, Black BE, et al. A core viral protein binds host nucleosomes to sequester immune danger signals. Nature. PMID 27362237 DOI: 10.1038/nature18317  1
2016 Bridges RG, Sohn SY, Wright J, Leppard KN, Hearing P. The Adenovirus E4-ORF3 Protein Stimulates SUMOylation of General Transcription Factor TFII-I to Direct Proteasomal Degradation. Mbio. 7. PMID 26814176 DOI: 10.1128/mBio.02184-15  1
2016 Zheng Y, Stamminger T, Hearing P. E2F/Rb Family Proteins Mediate Interferon Induced Repression of Adenovirus Immediate Early Transcription to Promote Persistent Viral Infection. Plos Pathogens. 12: e1005415. PMID 26809031 DOI: 10.1371/journal.ppat.1005415  1
2016 Guimet D, Hearing P. Adenovirus Replication Adenoviral Vectors For Gene Therapy: Second Edition. 59-84. DOI: 10.1016/B978-0-12-800276-6.00003-6  1
2015 Vink EI, Zheng Y, Yeasmin R, Stamminger T, Krug LT, Hearing P. Impact of Adenovirus E4-ORF3 Oligomerization and Protein Localization on Cellular Gene Expression. Viruses. 7: 2428-49. PMID 25984715 DOI: 10.3390/v7052428  1
2015 Sohn SY, Bridges RG, Hearing P. Proteomic analysis of ubiquitin-like posttranslational modifications induced by the adenovirus E4-ORF3 protein. Journal of Virology. 89: 1744-55. PMID 25410875 DOI: 10.1128/JVI.02892-14  1
2014 Zheng Y, Hearing P. The use of chromatin immunoprecipitation (ChIP) to study the binding of viral proteins to the adenovirus genome in vivo. Methods in Molecular Biology (Clifton, N.J.). 1089: 79-87. PMID 24132479 DOI: 10.1007/978-1-62703-679-5_6  1
2013 Guimet D, Hearing P. The adenovirus L4-22K protein has distinct functions in the posttranscriptional regulation of gene expression and encapsidation of the viral genome. Journal of Virology. 87: 7688-99. PMID 23637408 DOI: 10.1128/JVI.00859-13  1
2013 Wu K, Guimet D, Hearing P. The adenovirus L4-33K protein regulates both late gene expression patterns and viral DNA packaging. Journal of Virology. 87: 6739-47. PMID 23552425 DOI: 10.1128/JVI.00652-13  1
2012 Wu K, Orozco D, Hearing P. The adenovirus L4-22K protein is multifunctional and is an integral component of crucial aspects of infection. Journal of Virology. 86: 10474-83. PMID 22811519 DOI: 10.1128/JVI.01463-12  1
2012 Sohn SY, Hearing P. Adenovirus regulates sumoylation of Mre11-Rad50-Nbs1 components through a paralog-specific mechanism. Journal of Virology. 86: 9656-65. PMID 22740413 DOI: 10.1128/JVI.01273-12  1
2012 Patsalo V, Yondola MA, Luan B, Shoshani I, Kisker C, Green DF, Raleigh DP, Hearing P. Biophysical and functional analyses suggest that adenovirus E4-ORF3 protein requires higher-order multimerization to function against promyelocytic leukemia protein nuclear bodies. The Journal of Biological Chemistry. 287: 22573-83. PMID 22573317 DOI: 10.1074/jbc.M112.344234  1
2012 Vink EI, Yondola MA, Wu K, Hearing P. Adenovirus E4-ORF3-dependent relocalization of TIF1α and TIF1γ relies on access to the Coiled-Coil motif. Virology. 422: 317-25. PMID 22123502 DOI: 10.1016/j.virol.2011.10.033  1
2011 Sitaraman V, Hearing P, Ward CB, Gnatenko DV, Wimmer E, Mueller S, Skiena S, Bahou WF. Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector. Proceedings of the National Academy of Sciences of the United States of America. 108: 14294-9. PMID 21844368 DOI: 10.1073/pnas.1102883108  1
2011 Greer AE, Hearing P, Ketner G. The adenovirus E4 11 k protein binds and relocalizes the cytoplasmic P-body component Ddx6 to aggresomes. Virology. 417: 161-8. PMID 21700307 DOI: 10.1016/j.virol.2011.05.017  1
2011 Ma HC, Hearing P. Adenovirus structural protein IIIa is involved in the serotype specificity of viral DNA packaging. Journal of Virology. 85: 7849-55. PMID 21632753 DOI: 10.1128/JVI.00467-11  1
2011 Banerjee PS, Ostapchuk P, Hearing P, Carrico IS. Unnatural amino acid incorporation onto adenoviral (Ad) coat proteins facilitates chemoselective modification and retargeting of Ad type 5 vectors. Journal of Virology. 85: 7546-54. PMID 21613404 DOI: 10.1128/JVI.00118-11  1
2011 Alba R, Cots D, Ostapchuk P, Bosch A, Hearing P, Chillon M. Altering the Ad5 packaging domain affects the maturation of the Ad particles. Plos One. 6: e19564. PMID 21611162 DOI: 10.1371/journal.pone.0019564  1
2011 Sohn SY, Hearing P. Adenovirus sequesters phosphorylated STAT1 at viral replication centers and inhibits STAT dephosphorylation. Journal of Virology. 85: 7555-62. PMID 21593149 DOI: 10.1128/JVI.00513-11  1
2011 Ostapchuk P, Almond M, Hearing P. Characterization of Empty adenovirus particles assembled in the absence of a functional adenovirus IVa2 protein. Journal of Virology. 85: 5524-31. PMID 21450831 DOI: 10.1128/JVI.02538-10  1
2011 Karen KA, Hearing P. Adenovirus core protein VII protects the viral genome from a DNA damage response at early times after infection. Journal of Virology. 85: 4135-42. PMID 21345950 DOI: 10.1128/JVI.02540-10  1
2010 Banerjee PS, Ostapchuk P, Hearing P, Carrico I. Chemoselective attachment of small molecule effector functionality to human adenoviruses facilitates gene delivery to cancer cells. Journal of the American Chemical Society. 132: 13615-7. PMID 20831164 DOI: 10.1021/ja104547x  1
2010 Tang M, Naidu D, Hearing P, Handwerger S, Tabibzadeh S. LEFTY, a member of the transforming growth factor-beta superfamily, inhibits uterine stromal cell differentiation: a novel autocrine role. Endocrinology. 151: 1320-30. PMID 20056823 DOI: 10.1210/en.2009-1081  1
2009 Karen KA, Hoey PJ, Young CS, Hearing P. Temporal regulation of the Mre11-Rad50-Nbs1 complex during adenovirus infection. Journal of Virology. 83: 4565-73. PMID 19244322 DOI: 10.1128/JVI.00042-09  1
2009 Hearing P. Adenovirus transformation Dna Tumor Viruses. 145-162. DOI: 10.1007/978-0-387-68945-6_7  1
2008 Ullman AJ, Hearing P. Cellular proteins PML and Daxx mediate an innate antiviral defense antagonized by the adenovirus E4 ORF3 protein. Journal of Virology. 82: 7325-35. PMID 18480450 DOI: 10.1128/JVI.00723-08  1
2008 Wohl BP, Hearing P. Role for the L1-52/55K protein in the serotype specificity of adenovirus DNA packaging. Journal of Virology. 82: 5089-92. PMID 18337584 DOI: 10.1128/JVI.00040-08  1
2007 Yang J, Hearing P. Chromatin immunoprecipitation to study the binding of proteins to the adenovirus genome in vivo. Methods in Molecular Medicine. 131: 113-21. PMID 17656779  1
2007 Alba R, Hearing P, Bosch A, Chillon M. Differential amplification of adenovirus vectors by flanking the packaging signal with attB/attP-PhiC31 sequences: implications for helper-dependent adenovirus production. Virology. 367: 51-8. PMID 17560622 DOI: 10.1016/j.virol.2007.05.014  1
2007 Ullman AJ, Reich NC, Hearing P. Adenovirus E4 ORF3 protein inhibits the interferon-mediated antiviral response. Journal of Virology. 81: 4744-52. PMID 17301128 DOI: 10.1128/JVI.02385-06  1
2007 Yondola MA, Hearing P. The adenovirus E4 ORF3 protein binds and reorganizes the TRIM family member transcriptional intermediary factor 1 alpha. Journal of Virology. 81: 4264-71. PMID 17287283 DOI: 10.1128/JVI.02629-06  1
2006 Ostapchuk P, Anderson ME, Chandrasekhar S, Hearing P. The L4 22-kilodalton protein plays a role in packaging of the adenovirus genome. Journal of Virology. 80: 6973-81. PMID 16809303 DOI: 10.1128/JVI.00123-06  1
2006 Mikhailik A, Tang M, Hearing P, Ravishankar V, Tabibzadeh S. Tet responsive and adenovirus based constructs for regulated in vivo expression of Lefty. Frontiers in Bioscience : a Journal and Virtual Library. 11: 883-8. PMID 16146778 DOI: 10.2741/1844  1
2005 Ostapchuk P, Hearing P. Control of adenovirus packaging. Journal of Cellular Biochemistry. 96: 25-35. PMID 15988756 DOI: 10.1002/jcb.20523  1
2005 Tang M, Hearing P, Tabibzadeh S. Modeling gene expression in the mouse uterine horn by in vivo adenovirus-mediated gene delivery. Frontiers in Bioscience : a Journal and Virtual Library. 10: 2904-7. PMID 15970544  1
2005 Evans JD, Hearing P. Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication. Journal of Virology. 79: 6207-15. PMID 15858005 DOI: 10.1128/JVI.79.10.6207-6215.2005  1
2005 Ostapchuk P, Yang J, Auffarth E, Hearing P. Functional interaction of the adenovirus IVa2 protein with adenovirus type 5 packaging sequences. Journal of Virology. 79: 2831-8. PMID 15709002 DOI: 10.1128/JVI.79.5.2831-2838.2005  1
2005 Schaley JE, Polonskaia M, Hearing P. The adenovirus E4-6/7 protein directs nuclear localization of E2F-4 via an arginine-rich motif. Journal of Virology. 79: 2301-8. PMID 15681431 DOI: 10.1128/JVI.79.4.2301-2308.2005  1
2004 McDonald C, Vanscoy S, Hearing P, Reich NC. Induction of genes involved in cell cycle progression by interleukin-4. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 24: 729-38. PMID 15684740 DOI: 10.1089/jir.2004.24.729  1
2004 Gnatenko DV, Wu Y, Jesty J, Damon AL, Hearing P, Bahou WF. Expression of therapeutic levels of factor VIII in hemophilia A mice using a novel adeno/adeno-associated hybrid virus. Thrombosis and Haemostasis. 92: 317-27. PMID 15269828 DOI: 10.1160/TH04-02-0068  1
2003 Ostapchuk P, Hearing P. Regulation of adenovirus packaging Current Topics in Microbiology and Immunology. 272: 165-185. PMID 12747550  1
2003 Lang SE, Hearing P. The adenovirus E1A oncoprotein recruits the cellular TRRAP/GCN5 histone acetyltransferase complex. Oncogene. 22: 2836-41. PMID 12743606 DOI: 10.1038/sj.onc.1206376  1
2003 Erturk E, Ostapchuk P, Wells SI, Yang J, Gregg K, Nepveu A, Dudley JP, Hearing P. Binding of CCAAT displacement protein CDP to adenovirus packaging sequences. Journal of Virology. 77: 6255-64. PMID 12743282 DOI: 10.1128/JVI.77.11.6255-6264.2003  1
2003 Evans JD, Hearing P. Distinct roles of the Adenovirus E4 ORF3 protein in viral DNA replication and inhibition of genome concatenation. Journal of Virology. 77: 5295-304. PMID 12692231 DOI: 10.1128/JVI.77.9.5295-5304.2003  1
2003 Ostapchuk P, Hearing P. Minimal cis-acting elements required for adenovirus genome packaging. Journal of Virology. 77: 5127-35. PMID 12692215 DOI: 10.1128/JVI.77.9.5127-5135.2003  1
2002 Xiao W, Warrington KH, Hearing P, Hughes J, Muzyczka N. Adenovirus-facilitated nuclear translocation of adeno-associated virus type 2. Journal of Virology. 76: 11505-17. PMID 12388712 DOI: 10.1128/JVI.76.22.11505-11517.2002  1
2001 Lang SE, McMahon SB, Cole MD, Hearing P. E2F transcriptional activation requires TRRAP and GCN5 cofactors. The Journal of Biological Chemistry. 276: 32627-34. PMID 11418595 DOI: 10.1074/jbc.M102067200  1
2001 O'Connor RJ, Schaley JE, Feeney G, Hearing P. The p107 tumor suppressor induces stable E2F DNA binding to repress target promoters. Oncogene. 20: 1882-91. PMID 11313936 DOI: 10.1038/sj.onc.1204278  1
2001 Ostapchuk P, Hearing P. Pseudopackaging of adenovirus type 5 genomes into capsids containing the hexon proteins of adenovirus serotypes B, D, or E Journal of Virology. 75: 45-51. PMID 11119572 DOI: 10.1128/JVI.75.1.45-51.2001  1
2000 Sandalon Z, Gnatenko DV, Bahou WF, Hearing P. Adeno-associated virus (AAV) rep protein enhances the generation of a recombinant mini-adenovirus (Ad) utilizing an Ad/AAV hybrid virus Journal of Virology. 74: 10381-10389. PMID 11044082 DOI: 10.1128/JVI.74.22.10381-10389.2000  1
2000 Taylor LJ, Walsh AB, Hearing P, Bar-Sagi D. Single cell assays for Rac activity Methods in Enzymology. 325: 327-334. PMID 11036615  1
2000 O'Connor RJ, Hearing P. The E4-6/7 protein functionally compensates for the loss of E1A expression in adenovirus infection Journal of Virology. 74: 5819-5824. PMID 10846061 DOI: 10.1128/JVI.74.13.5819-5824.2000  1
2000 Schaley J, O'Connor RJ, Taylor LJ, Bar-Sagi D, Hearing P. Induction of the cellular E2F-1 promoter by the adenovirus E4-6/7 protein Journal of Virology. 74: 2084-2093. PMID 10666238 DOI: 10.1128/JVI.74.5.2084-2093.2000  1
1999 Gnatenko DV, Saenko EL, Jesty J, Cao LX, Hearing P, Bahou WF. Human factor VIII can be packaged and functionally expressed in an adeno-associated virus background: Applicability to haemophilia A gene therapy British Journal of Haematology. 104: 27-36. PMID 10027708 DOI: 10.1046/j.1365-2141.1999.01137.x  1
1998 Schmid SI, Hearing P. Cellular components interact with adenovirus type 5 minimal DNA packaging domains Journal of Virology. 72: 6339-6347. PMID 9658073  1
1998 Garry RT, Hearing P, Cosper EM. Characterization of a lytic virus infectious to the bloom-forming microalga Aureococcus anophagefferens (Pelagophyceae) Journal of Phycology. 34: 616-621.  1
1997 Schmid SI, Hearing P. Bipartite structure and functional independence of adenovirus type 5 packaging elements Journal of Virology. 71: 3375-3384. PMID 9094606  1
1995 David E, Garcia AD, Hearing P. Interaction of EF-C/RFX-1 with the inverted repeat of viral enhancer regions is required for transactivation Journal of Biological Chemistry. 270: 8353-8360. PMID 7713944 DOI: 10.1074/jbc.270.14.8353  1
1995 Schmid SI, Hearing P. Selective encapsidation of adenovirus DNA Current Topics in Microbiology and Immunology. 199: 67-80. PMID 7555061  1
1994 Obert S, O'Connor RJ, Schmid S, Hearing P. The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complex Molecular and Cellular Biology. 14: 1333-1346. PMID 8289811  1
1994 Ostapchuk P, Hearing P, Ganem D. A dramatic shift in the transmembrane topology of a viral envelope glycoprotein accompanies hepatitis B viral morphogenesis Embo Journal. 13: 1048-1057. PMID 8131739  1
1994 O'Connor RJ, Hearing P. Mutually exclusive interaction of the adenovirus E4-6/7 protein and the retinoblastoma gene product with internal domains of E2F-1 and DP-1 Journal of Virology. 68: 6848-6862. PMID 7933066  1
1994 Fujisawa H, Hearing P. Structure, function and specificity of the DNA packaging signals in double-stranded DNA viruses Seminars in Virology. 5: 5-13. DOI: 10.1006/smvy.1994.1002  1
1993 Hatfield L, Hearing P. The NFIII/OCT-1 binding site stimulates adenovirus DNA replication in vivo and is functionally redundant with adjacent sequences Journal of Virology. 67: 3931-3939. PMID 8510211  1
1993 Siegrist CA, Durand B, Emery P, David E, Hearing P, Mach B, Reith W. RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer Molecular and Cellular Biology. 13: 6375-6384. PMID 8413236  1
1993 Garcia AD, Ostapchuk P, Hearing P. Functional interaction of nuclear factors EF-C, HNF-4, and RXRα with hepatitis B virus enhancer I Journal of Virology. 67: 3940-3950. PMID 8389913  1
1992 Gräble M, Hearing P. Cis and trans requirements for the selective packaging of adenovirus type 5 DNA Journal of Virology. 66: 723-731. PMID 1731109  1
1992 Bolwig GM, Bruder JT, Hearing P. Different binding site requirements for binding and activation for the bipartite enhancer factor EF-1A. Nucleic Acids Research. 20: 6555-64. PMID 1336180 DOI: 10.1093/nar/20.24.6555  1
1991 Garcia AD, Ostapchuk P, Hearing P. Methylation-dependent and -independent DNA binding of nuclear factor EF-C Virology. 182: 857-860. PMID 1850932 DOI: 10.1016/0042-6822(91)90629-P  1
1991 Bolwig GM, Hearing P. Interaction of nuclear factor EF-1A with the polyomavirus enhancer region. Journal of Virology. 65: 1884-92. PMID 1848308  1
1991 O'connor RJ, Hearing P. The C-terminal 70 amino acids of the adenovirus E4-ORF6/7 protein are essential and sufficient for E2F complex formation Nucleic Acids Research. 19: 6579-6586. PMID 1836562 DOI: 10.1093/nar/19.23.6579  1
1991 Bruder JT, Hearing P. Cooperative binding of EF-1A to the E1A enhancer region mediates synergistic effects on E1A transcription during adenovirus infection Journal of Virology. 65: 5084-5087. PMID 1651424  1
1990 Grable M, Hearing P. Adenovirus type 5 packaging domain is composed of a repeated element that is functionally redundant Journal of Virology. 64: 2047-2056. PMID 2325200  1
1989 Huang MM, Hearing P. Adenovirus early region 4 encodes two gene products with redundant effects in lytic infection Journal of Virology. 63: 2605-2615. PMID 2724411  1
1989 Bruder JT, Hearing P. Nuclear factor EF-1A binds to the adenovirus E1A core enhancer element and to other transcriptional control regions Molecular and Cellular Biology. 9: 5143-5153. PMID 2601713  1
1989 Ostapchuk P, Scheirle G, Hearing P. Binding of nuclear factor EF-C to a functional domain of the hepatitis B virus enhancer region Molecular and Cellular Biology. 9: 2787-2797. PMID 2550788  1
1989 Leza MA, Hearing P. Independent cyclic AMP and E1A induction of adenovirus early region 4 expression Journal of Virology. 63: 3057-3064. PMID 2542614  1
1989 Huang MM, Hearing P. The adenovirus early region 4 open reading frame 6/7 protein regulates the DNA binding activity of the cellular transcription factor, E2F, through a direct complex Genes &Amp; Development. 3: 1699-1710. PMID 2532611  1
1988 Cortes P, Buckbinder L, Leza MA, Rak N, Hearing P, Merino A, Reinberg D. EivF, a factor required for transcription of the adenovirus EIV promoter, binds to an element involved in EIa-dependent activation and cAMP induction Genes &Amp; Development. 2: 975-990. PMID 2844626  1
1988 Leza MA, Hearing P. Cellular transcription factor binds to adenovirus early region promoters and to a cyclic AMP response element Journal of Virology. 62: 3003-3013. PMID 2839717  1
1988 Weisinger G, Remmers EF, Hearing P, Marcu KB. Multiple negative elements upstream of the murine c-myc gene share nuclear factor binding sites with SV40 and polyoma enhancers Oncogene. 3: 635-646. PMID 2577865  1
1987 Hearing P, Samulski RJ, Wishart WL, Shenk T. Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome Journal of Virology. 61: 2555-2558. PMID 3599182  1
1987 Cutt JR, Shenk T, Hearing P. Analysis of adenovirus early region 4-encoded polypeptides synthesized in productively infected cells Journal of Virology. 61: 543-552. PMID 2949089  1
1986 Ostapchuk P, Diffley JF, Bruder JT, Stillman B, Levine AJ, Hearing P. Interaction of a nuclear factor with the polyomavirus enhancer region. Proceedings of the National Academy of Sciences of the United States of America. 83: 8550-4. PMID 3022296 DOI: 10.1073/pnas.83.22.8550  1
1986 Hearing P, Shenk T. The adenovirus type 5 E1A enhancer contains two functionally distinct domains: One is specific for E1A and the other modulates all early units in cis Cell. 45: 229-236. PMID 2938742 DOI: 10.1016/0092-8674(86)90387-9  1
1985 Hearing P, Shenk T. Sequence-independent autoregulation of the adenovirus type 5 E1A transcription unit Molecular and Cellular Biology. 5: 3214-3221. PMID 2943984  1
1984 Sarnow P, Hearing P, Anderson CW, Halbert DN, Shenk T, Levine AJ. Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells. Journal of Virology. 49: 692-700. PMID 6699935  1
1983 Hearing P, Shenk T. The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element Cell. 33: 695-703. PMID 6871991 DOI: 10.1016/0092-8674(83)90012-0  1
1982 Sarnow P, Hearing P, Anderson CW, Reich N, Levine AJ. Identification and characterization of an immunologically conserved adenovirus early region 11,000 Mr protein and its association with the nuclear matrix. Journal of Molecular Biology. 162: 565-83. PMID 7166756 DOI: 10.1016/0022-2836(82)90389-8  1
1979 Rundell K, Hearing P, Yang YC. SV40 17K protein is associated with two cellular proteins Symposia On Quantitative Biology. 44: 211-214. PMID 6253134  1
1979 Yang YC, Hearing P, Rundell K. Cellular proteins associated with simian virus 40 early gene products in newly infected cells Journal of Virology. 32: 147-154. PMID 232167  1
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