Year |
Citation |
Score |
2023 |
Covert JD, Grice BA, Thornburg MG, Kaur M, Ryan AP, Tackett L, Bhamidipati T, Stull ND, Kim T, Habegger KM, McClain DA, Brozinick JT, Elmendorf JS. An early, reversible cholesterolgenic etiology of diet-induced insulin resistance. Molecular Metabolism. 72: 101715. PMID 37019209 DOI: 10.1016/j.molmet.2023.101715 |
0.791 |
|
2022 |
Merz KE, Tunduguru R, Ahn M, Salunkhe VA, Veluthakal R, Hwang J, Bhattacharya S, McCown EM, Garcia PA, Zhou C, Oh E, Yoder SM, Elmendorf JS, Thurmond DC. Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis. Frontiers in Endocrinology. 13: 821849. PMID 35222279 DOI: 10.3389/fendo.2022.821849 |
0.749 |
|
2019 |
Grice BA, Barton KJ, Covert JD, Kreilach AM, Tackett L, Brozinick JT, Elmendorf JS. Excess Membrane Cholesterol is an Early Contributing Reversible Aspect of Skeletal Muscle Insulin Resistance in C57BL/6NJ Mice Fed a Western-Style High-Fat Diet. American Journal of Physiology. Endocrinology and Metabolism. PMID 31237447 DOI: 10.1152/Ajpendo.00396.2018 |
0.619 |
|
2019 |
GRICE BA, COVERT JD, KREILACH AM, THORNBURG M, TACKETT L, MCCLAIN D, ELMENDORF JS. 266-LB: Evidence for a Hexosamine Biosynthesis Pathway-Mediated Sp1 Cholesterolgenic Response Being an Early Etiological Factor of Insulin Resistance Diabetes. 68: 266-LB. DOI: 10.2337/Db19-266-Lb |
0.617 |
|
2017 |
Tunduguru R, Zhang J, Aslamy A, Salunkhe VA, Brozinick JT, Elmendorf JS, Thurmond DC. The actin-related p41ARC subunit contributes to p21-activated kinase-1 (PAK1)-mediated glucose uptake into skeletal muscle cells. The Journal of Biological Chemistry. PMID 28972183 DOI: 10.1074/Jbc.M117.801340 |
0.788 |
|
2017 |
Ambery AG, Tackett L, Penque BA, Brozinick JT, Elmendorf JS. Exercise training prevents skeletal muscle plasma membrane cholesterol accumulation, cortical actin filament loss, and insulin resistance in C57BL/6J mice fed a western-style high-fat diet. Physiological Reports. 5. PMID 28811359 DOI: 10.14814/Phy2.13363 |
0.836 |
|
2017 |
Grice BA, Elmendorf JS. New Aspects of Cellular Cholesterol Regulation on Blood Glucose Control—Review and Perspective on the Impact of Statin Medications on Metabolic Health Us Endocrinology. 13: 63-68. DOI: 10.17925/Use.2017.13.02.63 |
0.385 |
|
2014 |
Ambery AG, Tackett L, Penque BA, Hickman DL, Elmendorf JS. Effect of Corncob bedding on feed conversion efficiency in a high-fat diet-induced prediabetic model in C57Bl/6J mice. Journal of the American Association For Laboratory Animal Science : Jaalas. 53: 449-51. PMID 25255066 |
0.75 |
|
2014 |
Tunduguru R, Chiu TT, Ramalingam L, Elmendorf JS, Klip A, Thurmond DC. Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells. Biochemical Pharmacology. 92: 380-8. PMID 25199455 DOI: 10.1016/J.Bcp.2014.08.033 |
0.817 |
|
2014 |
Hoffman NJ, Penque BA, Habegger KM, Sealls W, Tackett L, Elmendorf JS. Chromium enhances insulin responsiveness via AMPK. The Journal of Nutritional Biochemistry. 25: 565-72. PMID 24725432 DOI: 10.1016/J.Jnutbio.2014.01.007 |
0.87 |
|
2013 |
Penque BA, Hoggatt AM, Herring BP, Elmendorf JS. Hexosamine biosynthesis impairs insulin action via a cholesterolgenic response. Molecular Endocrinology (Baltimore, Md.). 27: 536-47. PMID 23315940 DOI: 10.1210/Me.2012-1213 |
0.87 |
|
2013 |
Penque BA, Tackett L, Elmendorf JS. Trivalent Chromium Modulates Hexosamine Biosynthesis Pathway Transcriptional Activation of Cholesterol Synthesis and Insulin Resistance Open Journal of Endocrine and Metabolic Diseases. 3: 1-8. DOI: 10.4236/Ojemd.2013.34A1001 |
0.878 |
|
2012 |
Elmendorf JS. Fretting about fat: a new look at the lipid droplet surface and the roundabout role of Plin2 in cellular lipid storage: focus on "Direct interaction of Plin2 with lipids on the surface of lipid droplets: a live cell FRET analysis". American Journal of Physiology. Cell Physiology. 303: C713-4. PMID 22855294 DOI: 10.1152/Ajpcell.00250.2012 |
0.31 |
|
2012 |
Habegger KM, Hoffman NJ, Ridenour CM, Brozinick JT, Elmendorf JS. AMPK enhances insulin-stimulated GLUT4 regulation via lowering membrane cholesterol. Endocrinology. 153: 2130-41. PMID 22434076 DOI: 10.1210/En.2011-2099 |
0.89 |
|
2012 |
Habegger KM, Penque BA, Sealls W, Tackett L, Bell LN, Blue EK, Gallagher PJ, Sturek M, Alloosh MA, Steinberg HO, Considine RV, Elmendorf JS. Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle. Diabetologia. 55: 457-67. PMID 22002007 DOI: 10.1007/S00125-011-2334-Y |
0.874 |
|
2011 |
Bhonagiri P, Pattar GR, Habegger KM, McCarthy AM, Tackett L, Elmendorf JS. Evidence coupling increased hexosamine biosynthesis pathway activity to membrane cholesterol toxicity and cortical filamentous actin derangement contributing to cellular insulin resistance. Endocrinology. 152: 3373-84. PMID 21712361 DOI: 10.1210/En.2011-1295 |
0.866 |
|
2011 |
Jewell JL, Oh E, Ramalingam L, Kalwat MA, Tagliabracci VS, Tackett L, Elmendorf JS, Thurmond DC. Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis. The Journal of Cell Biology. 193: 185-99. PMID 21444687 DOI: 10.1083/Jcb.201007176 |
0.755 |
|
2011 |
Sealls W, Penque BA, Elmendorf JS. Evidence that chromium modulates cellular cholesterol homeostasis and ABCA1 functionality impaired by hyperinsulinemia--brief report. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1139-40. PMID 21311039 DOI: 10.1161/Atvbaha.110.222158 |
0.783 |
|
2011 |
Hoffman NJ, Elmendorf JS. Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis. Trends in Endocrinology and Metabolism: Tem. 22: 110-6. PMID 21216617 DOI: 10.1016/J.Tem.2010.12.001 |
0.815 |
|
2010 |
Horvath EM, Tackett L, McCarthy AM, Raman P, Brozinick JT, Elmendorf JS. Antidiabetogenic effects of chromium mitigate hyperinsulinemia-induced cellular insulin resistance via correction of plasma membrane cholesterol imbalance (Molecular Endocrinology (2008) 22, (937-950) DOI: 10.1210/me.2007-0410) Molecular Endocrinology. 24: 1308. DOI: 10.1210/Me.2010-0167 |
0.779 |
|
2010 |
Bhonagiri P, Pattar GR, Horvath EM, Habegger KM, McCarthy AM, Elmendorf JS. Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin (Endocrinology (2009) 150, (1636-1645) DOI: 10.1210/en.2008-1102) Endocrinology. 151: 2967. DOI: 10.1210/En.2010-0489 |
0.843 |
|
2009 |
Bhonagiri P, Pattar GR, Horvath EM, Habegger KM, McCarthy AM, Elmendorf JS. Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin. Endocrinology. 150: 1636-45. PMID 19036880 DOI: 10.1210/En.2008-1102 |
0.865 |
|
2008 |
Horvath EM, Tackett L, Elmendorf JS. A novel membrane-based anti-diabetic action of atorvastatin. Biochemical and Biophysical Research Communications. 372: 639-43. PMID 18514061 DOI: 10.1016/J.Bbrc.2008.05.095 |
0.693 |
|
2008 |
Horvath EM, Tackett L, McCarthy AM, Raman P, Brozinick JT, Elmendorf JS. Antidiabetogenic effects of chromium mitigate hyperinsulinemia-induced cellular insulin resistance via correction of plasma membrane cholesterol imbalance. Molecular Endocrinology (Baltimore, Md.). 22: 937-50. PMID 18165437 DOI: 10.1210/Me.2007-0410 |
0.834 |
|
2007 |
Brozinick JT, Berkemeier BA, Elmendorf JS. "Actin"g on GLUT4: membrane & cytoskeletal components of insulin action. Current Diabetes Reviews. 3: 111-22. PMID 18220662 DOI: 10.2174/157339907780598199 |
0.727 |
|
2007 |
McCarthy AM, Elmendorf JS. GLUT4's itinerary in health & disease. The Indian Journal of Medical Research. 125: 373-88. PMID 17496362 |
0.803 |
|
2006 |
Strawbridge AB, Elmendorf JS, Mather KJ. Interactions of endothelin and insulin: expanding parameters of insulin resistance. Current Diabetes Reviews. 2: 317-27. PMID 18220636 DOI: 10.2174/157339906777950642 |
0.851 |
|
2006 |
Pattar GR, Tackett L, Liu P, Elmendorf JS. Chromium picolinate positively influences the glucose transporter system via affecting cholesterol homeostasis in adipocytes cultured under hyperglycemic diabetic conditions. Mutation Research. 610: 93-100. PMID 16870493 DOI: 10.1016/J.Mrgentox.2006.06.018 |
0.844 |
|
2006 |
McCarthy AM, Spisak KO, Brozinick JT, Elmendorf JS. Loss of cortical actin filaments in insulin-resistant skeletal muscle cells impairs GLUT4 vesicle trafficking and glucose transport. American Journal of Physiology. Cell Physiology. 291: C860-8. PMID 16774991 DOI: 10.1152/Ajpcell.00107.2006 |
0.833 |
|
2006 |
Chen G, Liu P, Pattar GR, Tackett L, Bhonagiri P, Strawbridge AB, Elmendorf JS. Chromium activates glucose transporter 4 trafficking and enhances insulin-stimulated glucose transport in 3T3-L1 adipocytes via a cholesterol-dependent mechanism. Molecular Endocrinology (Baltimore, Md.). 20: 857-70. PMID 16339278 DOI: 10.1210/Me.2005-0255 |
0.857 |
|
2006 |
Strawbridge AB, Elmendorf JS. Endothelin-1 impairs glucose transporter trafficking via a membrane-based mechanism. Journal of Cellular Biochemistry. 97: 849-56. PMID 16240321 DOI: 10.1002/Jcb.20687 |
0.877 |
|
2006 |
Habegger KM, Horvath EM, Elmendorf JS. DNP-Stimulated GLUT4 Translocation via 5???-AMP Activated Protein Kinase is Dependent on Plasma Membrane Cholesterol and Potentially Coupled Phosphoinositide-Regulated Actin Polymerization Events Medicine & Science in Sports & Exercise. 38: S8. DOI: 10.1249/00005768-200611001-00031 |
0.711 |
|
2005 |
Strawbridge AB, Elmendorf JS. Phosphatidylinositol 4,5-bisphosphate reverses endothelin-1-induced insulin resistance via an actin-dependent mechanism. Diabetes. 54: 1698-705. PMID 15919791 DOI: 10.2337/Diabetes.54.6.1698 |
0.882 |
|
2004 |
Chen G, Raman P, Bhonagiri P, Strawbridge AB, Pattar GR, Elmendorf JS. Protective effect of phosphatidylinositol 4,5-bisphosphate against cortical filamentous actin loss and insulin resistance induced by sustained exposure of 3T3-L1 adipocytes to insulin. The Journal of Biological Chemistry. 279: 39705-9. PMID 15277534 DOI: 10.1074/Jbc.C400171200 |
0.859 |
|
2004 |
Brozinick JT, Hawkins ED, Strawbridge AB, Elmendorf JS. Disruption of cortical actin in skeletal muscle demonstrates an essential role of the cytoskeleton in glucose transporter 4 translocation in insulin-sensitive tissues. The Journal of Biological Chemistry. 279: 40699-706. PMID 15247264 DOI: 10.1074/Jbc.M402697200 |
0.883 |
|
2004 |
Elmendorf JS. Fluidity of insulin action. Molecular Biotechnology. 27: 127-38. PMID 15208455 DOI: 10.1385/Mb:27:2:127 |
0.703 |
|
2004 |
Liu P, Leffler BJ, Weeks LK, Chen G, Bouchard CM, Strawbridge AB, Elmendorf JS. Sphingomyelinase activates GLUT4 translocation via a cholesterol-dependent mechanism. American Journal of Physiology. Cell Physiology. 286: C317-29. PMID 14522816 DOI: 10.1152/Ajpcell.00073.2003 |
0.835 |
|
2003 |
Lakshmanan J, Elmendorf JS, Ozcan S. Analysis of insulin-stimulated glucose uptake in differentiated 3T3-L1 adipocytes. Methods in Molecular Medicine. 83: 97-103. PMID 12619720 DOI: 10.1385/1-59259-377-1:097 |
0.595 |
|
2003 |
Chen G, Liu P, Thurmond DC, Elmendorf JS. Glucosamine-induced insulin resistance is coupled to O-linked glycosylation of Munc18c. Febs Letters. 534: 54-60. PMID 12527361 DOI: 10.1016/S0014-5793(02)03774-2 |
0.829 |
|
2002 |
Kralik SF, Liu P, Leffler BJ, Elmendorf JS. Ceramide and glucosamine antagonism of alternate signaling pathways regulating insulin- and osmotic shock-induced glucose transporter 4 translocation. Endocrinology. 143: 37-46. PMID 11751589 DOI: 10.1210/Endo.143.1.8606 |
0.672 |
|
2000 |
Yang C, Watson RT, Elmendorf JS, Sacks DB, Pessin JE. Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes. Molecular Endocrinology (Baltimore, Md.). 14: 317-26. PMID 10674403 DOI: 10.1210/Mend.14.2.0425 |
0.855 |
|
1999 |
Elmendorf JS, Boeglin DJ, Pessin JE. Temporal separation of insulin-stimulated GLUT4/IRAP vesicle plasma membrane docking and fusion in 3T3L1 adipocytes Journal of Biological Chemistry. 274: 37357-37361. PMID 10601305 DOI: 10.1074/Jbc.274.52.37357 |
0.691 |
|
1999 |
Elmendorf JS, Pessin JE. Insulin signaling regulating the trafficking and plasma membrane fusion of GLUT4-containing intracellular vesicles Experimental Cell Research. 253: 55-62. PMID 10579911 DOI: 10.1006/Excr.1999.4675 |
0.807 |
|
1999 |
Min J, Okada S, Kanzaki M, Elmendorf JS, Coker KJ, Ceresa BP, Syu LJ, Noda Y, Saltiel AR, Pessin JE. Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes. Molecular Cell. 3: 751-60. PMID 10394363 DOI: 10.1016/S1097-2765(01)80007-1 |
0.872 |
|
1999 |
Pessin JE, Thurmond DC, Elmendorf JS, Coker KJ, Okada S. Molecular basis of insulin-stimulated GLUT4 vesicle trafficking. Location! Location! Location! Journal of Biological Chemistry. 274: 2593-2596. PMID 9915783 DOI: 10.1074/Jbc.274.5.2593 |
0.809 |
|
1998 |
Thurmond DC, Ceresa BP, Okada S, Elmendorf JS, Coker K, Pessin JE. Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes Journal of Biological Chemistry. 273: 33876-33883. PMID 9837979 DOI: 10.1074/Jbc.273.50.33876 |
0.874 |
|
1998 |
Elmendorf JS, Chen D, Pessin JE. Guanosine 5'-O-(3-thiotriphosphate) (GTPγS) stimulation of GLUT4 translocation is tyrosine kinase-dependent Journal of Biological Chemistry. 273: 13289-13296. PMID 9582374 DOI: 10.1074/Jbc.273.21.13289 |
0.687 |
|
1997 |
Chen D, Elmendorf JS, Olson AL, Li X, Earp HS, Pessin JE. Osmotic shock stimulates GLUT4 translocation in 3T3L1 adipocytes by a novel tyrosine kinase pathway Journal of Biological Chemistry. 272: 27401-27410. PMID 9341192 DOI: 10.1074/Jbc.272.43.27401 |
0.8 |
|
1997 |
Turinsky J, Damrau-Abney A, Elmendorf JS, Smith TR. Effect of monensin of 2-deoxyglucose uptake, the insulin receptor and phosphatidylinositol 3-kinase activity in rat muscle Journal of Endocrinology. 154: 85-91. PMID 9246941 DOI: 10.1677/Joe.0.1540085 |
0.613 |
|
1997 |
Smith TR, Elmendorf JS, David TS, Turinsky J. Growth hormone-induced insulin resistance: Role of the insulin receptor, IRS-1, GLUT-1, and GLUT-4 American Journal of Physiology - Endocrinology and Metabolism. 272: E1071-E1079. PMID 9227454 DOI: 10.1152/Ajpendo.1997.272.6.E1071 |
0.685 |
|
1997 |
Elmendorf JS, Damrau-Abney A, Smith TR, David TS, Turinsky J. Phosphatidylinositol 3-kinase and dynamics of insulin resistance in denervated slow and fast muscles in vivo American Journal of Physiology - Endocrinology and Metabolism. 272: E661-E670. PMID 9142889 DOI: 10.1152/Ajpendo.1997.272.4.E661 |
0.583 |
|
1997 |
Smith TR, Elmendorf JS, David TS, Turinsky J. Growth hormone-induced insulin resistance: Role of the insulin receptor, IRS-1, GLUT-1 and GLUT-4 Faseb Journal. 11: A507. |
0.625 |
|
1996 |
Turinsky J, Nagel GW, Elmendorf JS, Damrau-Abney A, Smith TR. Sphingomyelinase stimulates 2-deoxyglucose uptake by skeletal muscle Biochemical Journal. 313: 215-222. PMID 8546686 DOI: 10.1042/Bj3130215 |
0.642 |
|
1996 |
Smith TR, Elmendorf JS, David TS, Turinsky J. GROWTH HORMONE AND POST-TRAUMATIC INSULIN RESISTANCE. Shock. 5: 51. DOI: 10.1097/00024382-199606002-00163 |
0.53 |
|
1995 |
Elmendorf JS, Damrauabney A, Smith TR, David TS, Turinsky J. Insulin-Stimulated Phosphatidylinositol 3-Kinase Activity and 2-Deoxy-D-Glucose Uptake in Rat Skeletal Muscles Biochemical and Biophysical Research Communications. 208: 1147-1153. PMID 7702613 DOI: 10.1006/Bbrc.1995.1453 |
0.649 |
|
1994 |
Turinsky J, Damrau-Abney A, Elmendorf JS. 188; INCREASED INTRACELLULAR SODIUM CONCENTRATION CAUSES INSULIN RESISTANCE IN SKELETAL MUSCLE Shock. 1: 53. DOI: 10.1097/00024382-199401001-00189 |
0.531 |
|
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