Yanping Zhang - Publications

Affiliations: 
Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Genetics

125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sanford JD, Franklin D, Grois GA, Jin A, Zhang Y. Carnitine o-octanoyltransferase (CROT) is a p53 target that promotes oxidative metabolism and cell survival following nutrient starvation. The Journal of Biological Chemistry. 104908. PMID 37307919 DOI: 10.1016/j.jbc.2023.104908  0.363
2022 Sanford JD, Jin A, Grois GA, Zhang Y. A role of cytoplasmic p53 in the regulation of metabolism shown by bat-mimicking p53 NLS mutant mice. Cell Reports. 42: 111920. PMID 36640361 DOI: 10.1016/j.celrep.2022.111920  0.421
2022 Franklin DA, Liu S, Jin A, Cui P, Guo Z, Arend KC, Moorman NJ, He S, Wang GG, Wan YY, Zhang Y. Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway. The Journal of Biological Chemistry. 102739. PMID 36435197 DOI: 10.1016/j.jbc.2022.102739  0.419
2022 Wang B, Gao J, Zhao Z, Zhong X, Cui H, Hou H, Zhang Y, Zheng J, Di J, Liu Y. Identification of a small-molecule RPL11 mimetic that inhibits tumor growth by targeting MDM2-p53 pathway. Molecular Medicine (Cambridge, Mass.). 28: 109. PMID 36071402 DOI: 10.1186/s10020-022-00537-x  0.363
2021 Sanford JD, Yang J, Han J, Tollini LA, Jin A, Zhang Y. MDMX is essential for the regulation of p53 protein levels in the absence of a functional MDM2 C-terminal tail. Bmc Molecular and Cell Biology. 22: 46. PMID 34551723 DOI: 10.1186/s12860-021-00385-3  0.825
2021 Yang J, Zhang Y. New insight into the role of MDMX in MDM2-mediated p53 degradation and anti-cancer drug development. Oncoscience. 8: 94-96. PMID 34386548 DOI: 10.18632/oncoscience.542  0.393
2021 Di J, Zhao G, Wang H, Wu Y, Zhao Z, Zhu B, Zhang Y, Zheng J, Liu Y, Hu Y. A p53/CPEB2 negative feedback loop regulates renal cancer cell proliferation and migration. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 34362680 DOI: 10.1016/j.jgg.2021.05.011  0.363
2020 Yang J, Jin A, Han J, Chen X, Zheng J, Zhang Y. MDMX recruits UbcH5c to facilitate MDM2 E3 ligase activity and subsequent p53 degradation in vivo. Cancer Research. PMID 33277368 DOI: 10.1158/0008-5472.CAN-20-0790  0.413
2018 Franklin D, Zhang Y. Nutrient availability dictates the regulation of metabolism by the ribosomal protein-MDM2-p53 pathway. Molecular & Cellular Oncology. 5: e1302904. PMID 30250882 DOI: 10.1080/23723556.2017.1302904  0.461
2018 Leslie PL, Franklin DA, Liu Y, Zhang Y. p53 Regulates the Expression of LRP1 and Apoptosis through a Stress Intensity-Dependent MicroRNA Feedback Loop. Cell Reports. 24: 1484-1495. PMID 30089260 DOI: 10.1016/J.Celrep.2018.07.010  0.417
2018 Liu Y, Leslie PL, Jin A, Itahana K, Graves LM, Zhang Y. p32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701004RR. PMID 29465311 DOI: 10.1096/Fj.201701004Rr  0.407
2017 Tian H, Tackmann NR, Jin A, Zheng J, Zhang Y. Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice. The Journal of Biological Chemistry. PMID 29123033 DOI: 10.1074/Jbc.Ra117.000122  0.495
2017 Di J, Tang J, Qian H, Franklin DA, Deisenroth C, Itahana Y, Zheng J, Zhang Y. p53 upregulates PLCε-IP3-Ca(2+) pathway and inhibits autophagy through its target gene Rap2B. Oncotarget. 8: 64657-64669. PMID 29029384 DOI: 10.18632/Oncotarget.18112  0.786
2017 Liu Y, Leslie PL, Jin A, Itahana K, Graves LM, Zhang Y. p32 heterozygosity protects against age- and diet-induced obesity by increasing energy expenditure. Scientific Reports. 7: 5754. PMID 28720899 DOI: 10.1038/S41598-017-06209-9  0.354
2017 Di J, Tang J, Qian H, Franklin DA, Deisenroth C, Itahana Y, Zheng J, Zhang Y. p53 upregulates PLCε-IP3-Ca2+ pathway and inhibits autophagy through its target gene Rap2B. Oncotarget. PMID 28586307 DOI: 10.18632/oncotarget.18112  0.375
2017 Okumu DO, East MP, Levine M, Herring LE, Zhang R, Gilbert TSK, Litchfield DW, Zhang Y, Graves LM. BIRC6 mediates imatinib resistance independently of Mcl-1. Plos One. 12: e0177871. PMID 28520795 DOI: 10.1371/Journal.Pone.0177871  0.33
2017 Liu S, Kim TH, Franklin DA, Zhang Y. Protection against High-Fat-Diet-Induced Obesity in MDM2(C305F) Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure. Cell Reports. 18: 1005-1018. PMID 28122227 DOI: 10.1016/J.Celrep.2016.12.086  0.374
2017 Tackmann NR, Zhang Y. Mouse modeling of the MDM2/MDMX-p53 signaling axis. Journal of Molecular Cell Biology. PMID 28096294 DOI: 10.1093/jmcb/mjx006  0.41
2016 Liu Y, Deisenroth C, Zhang Y. RP-MDM2-p53 Pathway: Linking Ribosomal Biogenesis and Tumor Surveillance. Trends in Cancer. 2: 191-204. PMID 28741571 DOI: 10.1016/J.Trecan.2016.03.002  0.772
2016 Deisenroth C, Franklin DA, Zhang Y. The Evolution of the Ribosomal Protein-MDM2-p53 Pathway. Cold Spring Harbor Perspectives in Medicine. 6. PMID 27908926 DOI: 10.1101/Cshperspect.A026138  0.775
2016 Franklin DA, He Y, Leslie PL, Tikunov AP, Fenger N, Macdonald JM, Zhang Y. p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway. Scientific Reports. 6: 38067. PMID 27901115 DOI: 10.1038/Srep38067  0.673
2016 Meng X, Tackmann NR, Liu S, Yang J, Dong J, Wu C, Cox AD, Zhang Y. RPL23 links oncogenic RAS signaling to p53-mediated tumor suppression. Cancer Research. PMID 27402081 DOI: 10.1158/0008-5472.Can-15-3420  0.363
2016 Pan W, Wang Q, Zhang Y, Zhang N, Qin J, Li W, Wang J, Wu F, Cao L, Xu G. Verteporfin can Reverse the Paclitaxel Resistance Induced by YAP Over-Expression in HCT-8/T Cells without Photoactivation through Inhibiting YAP Expression. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 481-490. PMID 27383277 DOI: 10.1159/000445640  0.375
2016 Zhang L, Zhang Y, Tai L, Jiang K, Xie C, Li Z, Lin YZ, Wei G, Lu W, Pan W. Functionalized cell nucleus-penetrating peptide combined with doxorubicin for synergistic treatment of glioma. Acta Biomaterialia. PMID 27370905 DOI: 10.1016/j.actbio.2016.06.031  0.446
2016 Zhang Y, Wang Y, Jiang Y, Pan W, Liu H, Yin J, Shen Y, Cao J. T follicular helper cells in patients with acute schistosomiasis. Parasites & Vectors. 9: 321. PMID 27266984 DOI: 10.1186/S13071-016-1602-6  0.371
2016 Kim J, Zhang Y, Pan W. Powerful and Adaptive Testing for Multi-trait and Multi-SNP Associations with GWAS and Sequencing Data. Genetics. PMID 27075728 DOI: 10.1534/genetics.115.186502  0.357
2016 Zhang Q, Sun Q, Zhang Y, Zhang H, Shan T, Han J, Pan W, Gu C, Xu R. Three-dimensional image fusion of CTA and angiography for real-time guidance during neurointerventional procedures. Journal of Neurointerventional Surgery. PMID 27048959 DOI: 10.1136/neurintsurg-2015-012216  0.324
2016 Kamio T, Gu BW, Olson TS, Zhang Y, Mason PJ, Bessler M. Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis. Plos One. 11: e0152263. PMID 27042854 DOI: 10.1371/Journal.Pone.0152263  0.488
2016 Pan W, Yang Y, Zhu H, Zhang Y, Zhou R, Sun X. KRAS mutation is a weak, but valid predictor for poor prognosis and treatment outcomes in NSCLC: A meta-analysis of 41 studies. Oncotarget. PMID 26840022 DOI: 10.18632/oncotarget.7080  0.379
2016 Ye R, Hu D, Zhang Y, Huang Y, Sun X, Wang J, Chen X, Zhou H, Zhang D, Mungthin M, Pan W. Distinctive origin of artemisinin-resistant Plasmodium falciparum on the China-Myanmar border. Scientific Reports. 6: 20100. PMID 26831371 DOI: 10.1038/srep20100  0.407
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... Zhang Y, ... Zhang Y, ... Zhang Y, ... Zhang Y, ... Zhang Y, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.452
2016 Liu XS, Chopp M, Pan WL, Wang XL, Fan BY, Zhang Y, Kassis H, Zhang RL, Zhang XM, Zhang ZG. MicroRNA-146a Promotes Oligodendrogenesis in Stroke. Molecular Neurobiology. PMID 26738853 DOI: 10.1007/S12035-015-9655-7  0.369
2016 Rezk MS, Abdel-Halim M, Keeton A, Franklin D, Bauer M, Boeckler FM, Engel M, Hartmann RW, Zhang Y, Piazza GA, Abadi AH. Synthesis and Optimization of New 3,6-Disubstitutedindole Derivatives and Their Evaluation as Anticancer Agents Targeting the MDM2/MDMx Complex. Chemical & Pharmaceutical Bulletin. 64: 34-41. PMID 26726742 DOI: 10.1248/Cpb.C15-00608  0.322
2015 Liu Y, Zhang Y. CHCHD2 connects mitochondrial metabolism to apoptosis. Molecular & Cellular Oncology. 2: e1004964. PMID 27308501 DOI: 10.1080/23723556.2015.1004964  0.329
2015 Zhang YL, Pan WQ. [Research Progress on Artemisinin Resistance in Plasmodium falciparum]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases. 33: 418-24. PMID 27089770  0.366
2015 Wienken M, Dickmanns A, Nemajerova A, Kramer D, Najafova Z, Weiss M, Karpiuk O, Kassem M, Zhang Y, Lozano G, Johnsen SA, Moll UM, Zhang X, Dobbelstein M. MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53. Molecular Cell. PMID 26748827 DOI: 10.1016/J.Molcel.2015.12.008  0.439
2015 He G, Zhou Y, Peng C, Zhang Y, Pan W. Dielectric and Ferroelectric Performance of Pb(Zr(x)Ti(1-x))O3 Thin Films with Compositional Gradients. Journal of Nanoscience and Nanotechnology. 15: 7099-103. PMID 26716290  0.323
2015 Wang X, Xu X, Lu X, Zhang Y, Pan W. Transcriptome Bioinformatical Analysis of Vertebrate Stages of Schistosoma japonicum Reveals Alternative Splicing Events. Plos One. 10: e0138470. PMID 26407301 DOI: 10.1371/journal.pone.0138470  0.402
2015 Zhang Y, Zhao J, Wang X, Xu X, Pan W. Evaluation of six novel antigens as potential biomarkers for the early immunodiagnosis of schistosomiasis. Parasites & Vectors. 8: 447. PMID 26338369 DOI: 10.1186/s13071-015-1048-2  0.392
2015 Wu XL, Mi ZP, Wang HS, Xu DM, Pei LX, Liu J, Shi W, Pan WC, Zhang LX, Chen LP, Zhang Y, Sun JH. [Effect of Acupuncture Combined Physical Training and Relearning on Stroke Rehabilitation: a Multi-center Randomized Controlled Clinical Study]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 35: 549-54. PMID 26159017  0.332
2015 Zhang Y, Zhao L, Guo R, Song N, Wang J, Cao Y, Orndorff W, Pan WP. Mercury adsorption characteristics of HBr-modified fly ash in an entrained-flow reactor. Journal of Environmental Sciences (China). 33: 156-62. PMID 26141888 DOI: 10.1016/J.Jes.2015.01.011  0.333
2015 Zhang B, Lu P, Liu H, Jiao L, Ye Z, Jaime M, Balakirev FF, Yuan H, Wu H, Pan W, Zhang Y. Quantum Oscillations in a Two-Dimensional Electron Gas at the Rocksalt/Zincblende Interface of PbTe/CdTe (111) Heterostructures. Nano Letters. 15: 4381-6. PMID 26046294 DOI: 10.1021/Acs.Nanolett.5B01605  0.339
2015 Fu W, Cheng Y, Zhang Y, Mo X, Li T, Liu Y, Wang P, Pan W, Chen Y, Xue Y, Ma D, Zhang Y, Han W. The Secreted Form of Transmembrane Protein 98 Promotes the Differentiation of T Helper 1 Cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. PMID 25946230 DOI: 10.1089/jir.2014.0110  0.424
2015 Ye R, Zhang D, Chen B, Zhu Y, Zhang Y, Wang S, Pan W. Transcription of the var genes from a freshly-obtained field isolate of Plasmodium falciparum shows more variable switching patterns than long laboratory-adapted isolates. Malaria Journal. 14: 66. PMID 25889871 DOI: 10.1186/s12936-015-0565-y  0.414
2015 Leslie PL, Ke H, Zhang Y. The MDM2 RING domain and central acidic domain play distinct roles in MDM2 protein homodimerization and MDM2-MDMX protein heterodimerization. The Journal of Biological Chemistry. 290: 12941-50. PMID 25809483 DOI: 10.1074/Jbc.M115.644435  0.389
2015 Bao L, Peng R, Wang Y, Ma R, Ren X, Meng W, Sun F, Fang J, Chen P, Wang Y, Chen Q, Cai J, Jin J, Guo J, Yang S, ... ... Zhang Y, et al. Significant reduction of antibiotic consumption and patients' costs after an action plan in China, 2010-2014. Plos One. 10: e0118868. PMID 25767891 DOI: 10.1371/Journal.Pone.0118868  0.337
2015 Zhen Y, Pan W, Hu F, Wu H, Feng J, Zhang Y, Chen J. Exogenous hydrogen sulfide exerts proliferation/anti-apoptosis/angiogenesis/migration effects via amplifying the activation of NF-κB pathway in PLC/PRF/5 hepatoma cells. International Journal of Oncology. 46: 2194-204. PMID 25738635 DOI: 10.3892/ijo.2015.2914  0.455
2015 Yang ZF, Mok CK, Liu XQ, Li XB, He JF, Guan WD, Xu YH, Pan WQ, Chen LY, Lin YP, Wu SG, Pan SH, Huang JC, Ding GY, Zheng K, ... Zhang YH, et al. Clinical, virological and immunological features from patients infected with re-emergent avian-origin human H7N9 influenza disease of varying severity in Guangdong province. Plos One. 10: e0117846. PMID 25723593 DOI: 10.1371/journal.pone.0117846  0.341
2015 Zhang Y, Pan W. Principal component regression and linear mixed model in association analysis of structured samples: competitors or complements? Genetic Epidemiology. 39: 149-55. PMID 25536929 DOI: 10.1002/gepi.21879  0.371
2015 Liu Y, Clegg HV, Leslie PL, Di J, Tollini LA, He Y, Kim TH, Jin A, Graves LM, Zheng J, Zhang Y. CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation. Cell Death and Differentiation. 22: 1035-46. PMID 25476776 DOI: 10.1038/cdd.2014.194  0.737
2015 He S, Zhang Y, Wang P, Xu X, Zhu K, Pan W, Liu W, Cai K, Sun J, Zhang W, Jiang X. Multiplexed microfluidic blotting of proteins and nucleic acids by parallel, serpentine microchannels. Lab On a Chip. 15: 105-12. PMID 25342223 DOI: 10.1039/C4Lc00901K  0.381
2015 Köck K, Pan WJ, Gow JM, Horner MJ, Gibbs JP, Colbert A, Goletz TJ, Newhall KJ, Rees WA, Sun Y, Zhang Y, O'Neill JC, Umble-Romero AN, Prokop SP, Krill CD, et al. Preclinical development of AMG 139, a human antibody specifically targeting IL-23. British Journal of Pharmacology. 172: 159-72. PMID 25205227 DOI: 10.1111/Bph.12904  0.351
2014 Yang ZF, He JF, Li XB, Guan WD, Ke CW, Wu SG, Pan SH, Li RF, Kang M, Wu J, Lin JY, Ding GY, Huang JC, Pan WQ, Zhou R, ... Zhang YH, et al. Epidemiological and viral genome characteristics of the first human H7N9 influenza infection in Guangdong Province, China. Journal of Thoracic Disease. 6: 1785-93. PMID 25589974 DOI: 10.3978/J.Issn.2072-1439.2014.12.09  0.334
2014 Zhang Y, Pan W. Adjusting for population stratification and relatedness with sequencing data. Bmc Proceedings. 8: S42. PMID 25519386 DOI: 10.1186/1753-6561-8-S1-S42  0.351
2014 Pan W, Shen Y, Han X, Wang Y, Liu H, Jiang Y, Zhang Y, Wang Y, Xu Y, Cao J. Transcriptome profiles of the protoscoleces of Echinococcus granulosus reveal that excretory-secretory products are essential to metabolic adaptation. Plos Neglected Tropical Diseases. 8: e3392. PMID 25500817 DOI: 10.1371/Journal.Pntd.0003392  0.433
2014 Meng X, Franklin DA, Dong J, Zhang Y. MDM2-p53 pathway in hepatocellular carcinoma. Cancer Research. 74: 7161-7. PMID 25477334 DOI: 10.1158/0008-5472.Can-14-1446  0.41
2014 Sun S, Sun M, Zhang Y, Cheng C, Waqas M, Yu H, He Y, Xu B, Wang L, Wang J, Yin S, Chai R, Li H. In vivo overexpression of X-linked inhibitor of apoptosis protein protects against neomycin-induced hair cell loss in the apical turn of the cochlea during the ototoxic-sensitive period. Frontiers in Cellular Neuroscience. 8: 248. PMID 25278835 DOI: 10.3389/Fncel.2014.00248  0.332
2014 Tollini LA, Jin A, Park J, Zhang Y. Regulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damage. Cancer Cell. 26: 235-47. PMID 25117711 DOI: 10.1016/J.Ccr.2014.06.006  0.824
2014 Liu Y, He Y, Jin A, Tikunov AP, Zhou L, Tollini LA, Leslie P, Kim TH, Li LO, Coleman RA, Gu Z, Chen YQ, Macdonald JM, Graves LM, Zhang Y. Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation. Proceedings of the National Academy of Sciences of the United States of America. 111: E2414-22. PMID 24872453 DOI: 10.1073/Pnas.1315605111  0.798
2014 Ren Y, Feng X, Zou Y, Pan W, Wang X, Pan J, Zhang M, Tao J, Zhang Y, Tan K, Li J, Ding X, Qian X, Da Z, Wang M, et al. [Clinical features and prognosis of patients with lupus nephritis]. Zhonghua Yi Xue Za Zhi. 94: 973-6. PMID 24851681  0.332
2014 Pan W, Kim J, Zhang Y, Shen X, Wei P. A powerful and adaptive association test for rare variants. Genetics. 197: 1081-95. PMID 24831820 DOI: 10.1534/genetics.114.165035  0.348
2014 He Y, Tollini L, Kim TH, Itahana Y, Zhang Y. The anaphase-promoting complex/cyclosome is an E3 ubiquitin ligase for Mdm2. Cell Cycle (Georgetown, Tex.). 13: 2101-9. PMID 24804778 DOI: 10.4161/Cc.29106  0.8
2014 Zhang Y, Xu Z, Shen X, Pan W. Testing for association with multiple traits in generalized estimation equations, with application to neuroimaging data. Neuroimage. 96: 309-25. PMID 24704269 DOI: 10.1016/j.neuroimage.2014.03.061  0.349
2014 Kim TH, Leslie P, Zhang Y. Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability. Oncotarget. 5: 860-71. PMID 24658219 DOI: 10.18632/Oncotarget.1784  0.488
2014 Xu X, Zhang Y, Lin D, Zhang J, Xu J, Liu YM, Hu F, Qing X, Xia C, Pan W. Serodiagnosis of Schistosoma japonicum infection: genome-wide identification of a protein marker, and assessment of its diagnostic validity in a field study in China. The Lancet. Infectious Diseases. 14: 489-97. PMID 24656567 DOI: 10.1016/S1473-3099(14)70067-2  0.393
2014 Li Z, Zhang Y, Ying X, Song J, Zhang R, Li Z, Chen H, Ye P, Shen Y, Pan W, Chen Z. The association between RAD23B Ala249Val polymorphism and cancer susceptibility: evidence from a meta-analysis. Plos One. 9: e91922. PMID 24643114 DOI: 10.1371/journal.pone.0091922  0.364
2014 Feng X, Zou Y, Pan W, Wang X, Wu M, Zhang M, Tao J, Zhang Y, Tan K, Li J, Chen Z, Ding X, Qian X, Da Z, Wang M, et al. Associations of clinical features and prognosis with age at disease onset in patients with systemic lupus erythematosus. Lupus. 23: 327-34. PMID 24297642 DOI: 10.1177/0961203313513508  0.367
2014 Kamio T, Gu B, Olson TS, Zhang Y, Mason PJ, Bessler M. Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop Bone Marrow Failure Blood. 124: 4381-4381. DOI: 10.1182/Blood.V124.21.4381.4381  0.455
2013 Duan Z, DU FY, Yuan YD, Zhang YP, Yang HS, Pan WS. [Effects of PM2.5 exposure on Klebsiella pneumoniae clearance in the lungs of rats]. Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases. 36: 836-40. PMID 24507396  0.337
2013 Yu C, Zhang YL, Pan WW, Li XM, Wang ZW, Ge ZJ, Zhou JJ, Cang Y, Tong C, Sun QY, Fan HY. CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. Science (New York, N.Y.). 342: 1518-21. PMID 24357321 DOI: 10.1126/Science.1244587  0.435
2013 He X, Sai X, Chen C, Zhang Y, Xu X, Zhang D, Pan W. Host serum miR-223 is a potential new biomarker for Schistosoma japonicum infection and the response to chemotherapy. Parasites & Vectors. 6: 272. PMID 24330517 DOI: 10.1186/1756-3305-6-272  0.374
2013 Kim T, Zhang Y. Abstract A29: Mdm2 E3 ubiquitin ligase function is dispensable for the degradation of Mdm2 itself Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-A29  0.475
2012 Tollini LA, Zhang Y. p53 Regulation Goes Live-Mdm2 and MdmX Co-Star: Lessons Learned from Mouse Modeling. Genes & Cancer. 3: 219-25. PMID 23150755 DOI: 10.1177/1947601912454732  0.832
2012 Clegg HV, Itahana Y, Itahana K, Ramalingam S, Zhang Y. Mdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction. Plos One. 7: e38212. PMID 22666487 DOI: 10.1371/Journal.Pone.0038212  0.823
2012 Pei D, Zhang Y, Zheng J. Regulation of p53: a collaboration between Mdm2 and Mdmx. Oncotarget. 3: 228-35. PMID 22410433 DOI: 10.18632/Oncotarget.443  0.524
2011 Sasaki M, Kawahara K, Nishio M, Mimori K, Kogo R, Hamada K, Itoh B, Wang J, Komatsu Y, Yang YR, Hikasa H, Horie Y, Yamashita T, Kamijo T, Zhang Y, et al. Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11. Nature Medicine. 17: 944-51. PMID 21804542 DOI: 10.1038/Nm.2392  0.486
2011 Deisenroth C, Zhang Y. The Ribosomal Protein-Mdm2-p53 Pathway and Energy Metabolism: Bridging the Gap between Feast and Famine. Genes & Cancer. 2: 392-403. PMID 21779508 DOI: 10.1177/1947601911409737  0.781
2011 Pan W, Issaq S, Zhang Y. The in vivo role of the RP-Mdm2-p53 pathway in signaling oncogenic stress induced by pRb inactivation and Ras overexpression. Plos One. 6: e21625. PMID 21747916 DOI: 10.1371/Journal.Pone.0021625  0.611
2011 Deisenroth C, Itahana Y, Tollini L, Jin A, Zhang Y. p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation. The Journal of Biological Chemistry. 286: 28343-56. PMID 21659514 DOI: 10.1074/Jbc.M111.254227  0.776
2011 Li DQ, Pakala SB, Reddy SD, Ohshiro K, Zhang JX, Wang L, Zhang Y, Moreno de Alborán I, Pillai MR, Eswaran J, Kumar R. Bidirectional autoregulatory mechanism of metastasis-associated protein 1-alternative reading frame pathway in oncogenesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 8791-6. PMID 21555589 DOI: 10.1073/Pnas.1018389108  0.448
2011 Miliani de Marval PL, Zhang Y. The RP-Mdm2-p53 pathway and tumorigenesis. Oncotarget. 2: 234-8. PMID 21406728 DOI: 10.18632/oncotarget.228  0.348
2011 Kawahara K, Sasaki M, Nishio M, Mimori K, Kogo R, Zhang Y, Maehama T, Mori M, Suzuki A. Abstract PR9: PICT1/GLTSCR2 is a critical nucleolar binding partner of RPL11 that regulates the MDM2-p53 pathway and tumor growth Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-Pr9  0.49
2010 Frum RA, Zhang Y. The RP-p53-Mdm2 pathway Cell Cycle. PMID 21135577 DOI: 10.4161/Cc.9.22.13606  0.448
2010 Macias E, Jin A, Deisenroth C, Bhat K, Mao H, Lindström MS, Zhang Y. An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction. Cancer Cell. 18: 231-43. PMID 20832751 DOI: 10.1016/J.Ccr.2010.08.007  0.802
2010 Deisenroth C, Thorner AR, Enomoto T, Perou CM, Zhang Y. Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53. Molecular and Cellular Biology. 30: 3981-93. PMID 20547751 DOI: 10.1128/Mcb.01284-09  0.792
2010 Clegg HV, Zhang Y. Regulation of the p53 tumor suppressor pathway: the problems and promises of studying Mdm2's E3 ligase function. Critical Reviews in Eukaryotic Gene Expression. 20: 77-86. PMID 20528739 DOI: 10.1615/Critreveukargeneexpr.V20.I1.60  0.824
2009 Zhang Y, Lu H. Signaling to p53: ribosomal proteins find their way. Cancer Cell. 16: 369-377. PMID 19878869 DOI: 10.1016/J.Ccr.2009.09.024  0.448
2009 Li DQ, Reddy SDN, Pakala SB, Wu X, Zhang Y, Rayala SK, Kumar R. MTA1 coregulator regulates p53 stability and function. Journal of Biological Chemistry. 284: 34545-34552. PMID 19837670 DOI: 10.1074/Jbc.M109.056499  0.434
2009 Fu W, Ma Q, Chen L, Li P, Zhang M, Ramamoorthy S, Nawaz Z, Shimojima T, Wang H, Yang Y, Shen Z, Zhang Y, Zhang X, Nicosia SV, Zhang Y, et al. MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation. The Journal of Biological Chemistry. 284: 13987-4000. PMID 19321440 DOI: 10.1074/Jbc.M901758200  0.48
2009 Huang M, Itahana K, Zhang Y, Mitchell BS. Depletion of guanine nucleotides leads to the Mdm2-dependent proteasomal degradation of nucleostemin. Cancer Research. 69: 3004-12. PMID 19318567 DOI: 10.1158/0008-5472.Can-08-3413  0.405
2009 Itahana Y, Ke H, Zhang Y. p53 Oligomerization is essential for its C-terminal lysine acetylation. The Journal of Biological Chemistry. 284: 5158-64. PMID 19106109 DOI: 10.1074/Jbc.M805696200  0.458
2008 Itahana K, Clegg HV, Zhang Y. ARF in the mitochondria: the last frontier? Cell Cycle (Georgetown, Tex.). 7: 3641-6. PMID 19033735 DOI: 10.4161/Cc.7.23.7105  0.812
2008 Ma LD, Zhang Y, Wen SH, He YJ, Liu XS, Kang GF, Jiang JK. [Enhancing effect of matrine on the tumor-inhibition by TIM2 gene-modified hepatocarcinoma H22 cells in mice]. Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]. 30: 255-8. PMID 18788626  0.529
2008 Ma LD, Zhang Y, Wen SH, He YJ, Liu XS, Kang GF, Jiang JK. [Effects of matrine on oncogenicity of H22 cells modified by TIM2 gene in vivo]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 33: 1175-9. PMID 18720871  0.521
2008 Itahana K, Zhang Y. Mitochondrial p32 Is a Critical Mediator of ARF-Induced Apoptosis Cancer Cell. 13: 542-553. PMID 18538737 DOI: 10.1016/J.Ccr.2008.04.002  0.467
2008 Lindström MS, Zhang Y. Ribosomal protein S9 is a novel B23/NPM-binding protein required for normal cell proliferation. Journal of Biological Chemistry. 283: 15568-15576. PMID 18420587 DOI: 10.1074/Jbc.M801151200  0.331
2008 Clegg HV, Itahana K, Zhang Y. Unlocking the Mdm2-p53 loop: ubiquitin is the key. Cell Cycle (Georgetown, Tex.). 7: 287-92. PMID 18235222 DOI: 10.4161/Cc.7.3.5358  0.819
2008 Huang M, Ji Y, Itahana K, Zhang Y, Mitchell B. Guanine nucleotide depletion inhibits pre-ribosomal RNA synthesis and causes nucleolar disruption. Leukemia Research. 32: 131-41. PMID 17462731 DOI: 10.1016/J.Leukres.2007.03.025  0.365
2007 Itahana K, Mao H, Jin A, Itahana Y, Clegg HV, Lindström MS, Bhat KP, Godfrey VL, Evan GI, Zhang Y. Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation. Cancer Cell. 12: 355-66. PMID 17936560 DOI: 10.1016/J.Ccr.2007.09.007  0.818
2007 Lindström MS, Deisenroth C, Zhang Y. Putting a Finger on Growth Surveillance Insight into MDM2 Zinc Finger-Ribosomal Protein Interactions Cell Cycle. 6: 434-437. PMID 17329973 DOI: 10.4161/Cc.6.4.3861  0.771
2007 Lindström MS, Jin A, Deisenroth C, White Wolf G, Zhang Y. Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation. Molecular and Cellular Biology. 27: 1056-68. PMID 17116689 DOI: 10.1128/Mcb.01307-06  0.781
2006 He YF, Zhang YJ, Li YH, Lin TY, Xia YF, Lu TX, Huang HQ, Jiang WQ, Xian CG, He YJ, Guan ZZ. [Primary non-Hodgkin's lymphoma of the nasal cavity at early stage: long-term treatment outcomes and prognostic analyses of 108 cases]. Ai Zheng = Aizheng = Chinese Journal of Cancer. 25: 1538-42. PMID 17166382  0.475
2006 Lindström MS, Zhang Y. B23 and ARF: friends or foes? Cell Biochemistry and Biophysics. 46: 79-90. PMID 16943625 DOI: 10.1385/Cbb:46:1:79  0.317
2006 Dai MS, Shi D, Jin Y, Sun XX, Zhang Y, Grossman SR, Lu H. Regulation of the MDM2-p53 pathway by ribosomal protein L11 involves a post-ubiquitination mechanism. The Journal of Biological Chemistry. 281: 24304-13. PMID 16803902 DOI: 10.1074/Jbc.M602596200  0.386
2006 Itahana Y, Yeh ET, Zhang Y. Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2. Molecular and Cellular Biology. 26: 4675-89. PMID 16738331 DOI: 10.1128/Mcb.01830-05  0.37
2006 Enomoto T, Lindström MS, Jin A, Ke H, Zhang Y. Essential role of the B23/NPM core domain in regulating ARF binding and B23 stability. The Journal of Biological Chemistry. 281: 18463-72. PMID 16679321 DOI: 10.1074/Jbc.M602788200  0.317
2005 Ma LD, Zhang Y, Wen SH, He YJ, Liu XS, Kang GF, Jiang JK. [Inhibition of tumor growth in tumor-bearing mice treated with matrine]. Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]. 27: 339-41. PMID 16117895  0.532
2005 He YJ, Ou YH, Zhang Y, Liu XS, Ma LD, Jiang JK. [Construction of eukaryotic expression vector of unknown KH gene and its effect on cell proliferation]. Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]. 27: 129-33. PMID 15946558  0.507
2005 Li HP, Zhang YP. [Nuclear import of p53 in relation to MDM2-mediated degradation and ubiquitination]. Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]. 27: 86-9. PMID 15946545  0.381
2004 Jin A, Itahana K, O'Keefe K, Zhang Y. Inhibition of HDM2 and activation of p53 by ribosomal protein L23 Molecular and Cellular Biology. 24: 7669-7680. PMID 15314174 DOI: 10.1128/Mcb.24.17.7669-7680.2004  0.383
2004 Zhang Y, Ma LD, He YJ, Jiang JK. [Gene expression profile in early differentiation of K562 cells induced by matrine]. Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi. 25: 342-5. PMID 15308011  0.516
2004 Bhat KP, Itahana K, Jin A, Zhang Y. Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation. The Embo Journal. 23: 2402-12. PMID 15152193 DOI: 10.1038/Sj.Emboj.7600247  0.387
2004 Zhang Y. The ARF-B23 connection: implications for growth control and cancer treatment. Cell Cycle (Georgetown, Tex.). 3: 259-62. PMID 14726681  0.359
2003 Itahana K, Bhat KP, Jin A, Itahana Y, Hawke D, Kobayashi R, Zhang Y. Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation. Molecular Cell. 12: 1151-64. PMID 14636574 DOI: 10.1016/S1097-2765(03)00431-3  0.432
2003 Zhang Y, Wolf GW, Bhat K, Jin A, Allio T, Burkhart WA, Xiong Y. Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway. Molecular and Cellular Biology. 23: 8902-12. PMID 14612427 DOI: 10.1128/Mcb.23.23.8902-8912.2003  0.515
2003 O'Keefe K, Li H, Zhang Y. Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination. Molecular and Cellular Biology. 23: 6396-405. PMID 12944468 DOI: 10.1128/Mcb.23.18.6396-6405.2003  0.482
2003 Schneiderhan N, Budde A, Zhang Y, Brüne B. Nitric oxide induces phosphorylation of p53 and impairs nuclear export. Oncogene. 22: 2857-68. PMID 12771937 DOI: 10.1038/sj.onc.1206431  0.396
2002 Liu BZ, Jiang JK, He YJ, Zhang Y, Liu XS. [Effects of matrine on the activity of protein tyrosine kinase and phosphatase in K562 cells]. Ai Zheng = Aizheng = Chinese Journal of Cancer. 21: 1292-5. PMID 12520733  0.514
2002 He YJ, Jiang JK, Ou YH, Liu BZ, Liu XS, Zhang Y, Ma LD, Tu ZG. [Matrine affects early expression of proto-oncogenes in K562 cells]. Ai Zheng = Aizheng = Chinese Journal of Cancer. 21: 369-72. PMID 12452013  0.539
2001 Zhang LP, Jiang JK, Tam JW, Zhang Y, Liu XS, Xu XR, Liu BZ, He YJ. Effects of Matrine on proliferation and differentiation in K-562 cells. Leukemia Research. 25: 793-800. PMID 11489473  0.54
2001 Zhang Y, Xiong Y. A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation Science. 292: 1910-1915. PMID 11397945 DOI: 10.1126/Science.1058637  0.466
2000 Furukawa M, Zhang Y, McCarville J, Ohta T, Xiong Y. The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1. Molecular and Cellular Biology. 20: 8185-97. PMID 11027288 DOI: 10.1128/Mcb.20.21.8185-8197.2000  0.357
1999 Stewart S, Sundaram M, Zhang Y, Lee J, Han M, Guan KL. Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization. Molecular and Cellular Biology. 19: 5523-34. PMID 10409742 DOI: 10.1128/Mcb.19.8.5523  0.335
1999 Zhang Y, Xiong Y. Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53. Molecular Cell. 3: 579-91. PMID 10360174 DOI: 10.1016/S1097-2765(00)80351-2  0.487
1998 Zhang Y, Xiong Y, Yarbrough WG. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell. 92: 725-34. PMID 9529249 DOI: 10.1016/S0092-8674(00)81401-4  0.516
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