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Jonathan L. Linehan, Ph.D. - Publications

Affiliations: 
2012 Microbiology, Immunology and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Immunology
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bhattacharjee A, Burr AHP, Overacre-Delgoffe AE, Tometich JT, Yang D, Huckestein BR, Linehan JL, Spencer SP, Hall JA, Harrison OJ, Morais da Fonseca D, Norton EB, Belkaid Y, Hand TW. Environmental enteric dysfunction induces regulatory T cells that inhibit local CD4+ T cell responses and impair oral vaccine efficacy. Immunity. PMID 34348118 DOI: 10.1016/j.immuni.2021.07.005  0.446
2020 Hurabielle C, Link VM, Bouladoux N, Han SJ, Merrill ED, Lightfoot YL, Seto N, Bleck CKE, Smelkinson M, Harrison OJ, Linehan JL, Tamoutounour S, Lionakis MS, Kaplan MJ, Nakajima S, et al. Immunity to commensal skin fungi promotes psoriasiform skin inflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32601220 DOI: 10.1073/Pnas.2003022117  0.371
2019 Tamoutounour S, Han SJ, Deckers J, Constantinides MG, Hurabielle C, Harrison OJ, Bouladoux N, Linehan JL, Link VM, Vujkovic-Cvijin I, Perez-Chaparro PJ, Rosshart SP, Rehermann B, Lazarevic V, Belkaid Y. Keratinocyte-intrinsic MHCII expression controls microbiota-induced Th1 cell responses. Proceedings of the National Academy of Sciences of the United States of America. PMID 31672911 DOI: 10.1073/Pnas.1912432116  0.49
2019 Linehan JL, Delamarre L. Teamwork by different T-cell types boosts tumour destruction by immunotherapy. Nature. 574: 639-640. PMID 31659314 DOI: 10.1038/D41586-019-03106-1  0.633
2019 Constantinides MG, Link VM, Tamoutounour S, Wong AC, Perez-Chaparro PJ, Han SJ, Chen YE, Li K, Farhat S, Weckel A, Krishnamurthy SR, Vujkovic-Cvijin I, Linehan JL, Bouladoux N, Merrill ED, et al. MAIT cells are imprinted by the microbiota in early life and promote tissue repair. Science (New York, N.Y.). 366. PMID 31649166 DOI: 10.1126/Science.Aax6624  0.488
2019 Kotov JA, Kotov DI, Linehan JL, Bardwell VJ, Gearhart MD, Jenkins MK. BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors. The Journal of Experimental Medicine. PMID 31053612 DOI: 10.1084/Jem.20182376  0.7
2019 Constantinides MG, Tamoutounour S, Linehan JL, Sen S, Shaik J, Roy S, Adams EJ, Belkaid Y. Abstract PR16: Mucosal-associated invariant T-cells respond to the cutaneous microbiota and promote skin immunity Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-Pr16  0.551
2018 Harrison OJ, Linehan JL, Shih HY, Bouladoux N, Han SJ, Smelkinson M, Sen SK, Byrd AL, Enamorado M, Yao C, Tamoutounour S, Van Laethem F, Hurabielle C, Collins N, Paun A, et al. Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury. Science (New York, N.Y.). PMID 30523076 DOI: 10.1126/Science.Aat6280  0.516
2018 Linehan JL, Harrison OJ, Han SJ, Byrd AL, Vujkovic-Cvijin I, Villarino AV, Sen SK, Shaik J, Smelkinson M, Tamoutounour S, Collins N, Bouladoux N, Dzutsev A, Rosshart SP, Arbuckle JH, et al. Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair. Cell. PMID 29358051 DOI: 10.1016/J.Cell.2017.12.033  0.413
2016 Kalekar LA, Schmiel SE, Nandiwada SL, Lam WY, Barsness LO, Zhang N, Stritesky GL, Malhotra D, Pauken KE, Linehan JL, O'Sullivan MG, Fife BT, Hogquist KA, Jenkins MK, Mueller DL. CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors. Nature Immunology. PMID 26829766 DOI: 10.1038/Ni.3331  0.759
2016 Malhotra D, Linehan JL, Dileepan T, Lee YJ, Purtha WE, Lu JV, Nelson RW, Fife BT, Orr HT, Anderson MS, Hogquist KA, Jenkins MK. Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns. Nature Immunology. PMID 26726812 DOI: 10.1038/Ni.3327  0.717
2015 Linehan JL, Dileepan T, Kashem SW, Kaplan DH, Cleary P, Jenkins MK. Generation of Th17 cells in response to intranasal infection requires TGF-β1 from dendritic cells and IL-6 from CD301b+ dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 12782-7. PMID 26417101 DOI: 10.1073/Pnas.1513532112  0.698
2015 Naik S, Bouladoux N, Linehan JL, Han SJ, Harrison OJ, Wilhelm C, Conlan S, Himmelfarb S, Byrd AL, Deming C, Quinones M, Brenchley JM, Kong HH, Tussiwand R, Murphy KM, et al. Commensal-dendritic-cell interaction specifies a unique protective skin immune signature. Nature. 520: 104-8. PMID 25539086 DOI: 10.1038/Nature14052  0.421
2014 King C, Garza EN, Mazor R, Linehan JL, Pastan I, Pepper M, Baker D. Removing T-cell epitopes with computational protein design. Proceedings of the National Academy of Sciences of the United States of America. 111: 8577-82. PMID 24843166 DOI: 10.1073/Pnas.1321126111  0.495
2014 Yang Y, Torchinsky MB, Gobert M, Xiong H, Xu M, Linehan JL, Alonzo F, Ng C, Chen A, Lin X, Sczesnak A, Liao JJ, Torres VJ, Jenkins MK, Lafaille JJ, et al. Focused specificity of intestinal TH17 cells towards commensal bacterial antigens. Nature. 510: 152-6. PMID 24739972 DOI: 10.1038/Nature13279  0.735
2013 Pauken KE, Linehan JL, Spanier JA, Sahli NL, Kalekar LA, Binstadt BA, Moon JJ, Mueller DL, Jenkins MK, Fife BT. Cutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice. Journal of Immunology (Baltimore, Md. : 1950). 191: 4913-7. PMID 24123682 DOI: 10.4049/Jimmunol.1301927  0.663
2013 Tubo NJ, Pagán AJ, Taylor JJ, Nelson RW, Linehan JL, Ertelt JM, Huseby ES, Way SS, Jenkins MK. Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell. 153: 785-96. PMID 23663778 DOI: 10.1016/J.Cell.2013.04.007  0.694
2011 Dileepan T, Linehan JL, Moon JJ, Pepper M, Jenkins MK, Cleary PP. Robust antigen specific th17 T cell response to group A Streptococcus is dependent on IL-6 and intranasal route of infection. Plos Pathogens. 7: e1002252. PMID 21966268 DOI: 10.1371/Journal.Ppat.1002252  0.698
2010 Pepper M, Linehan JL, Pagán AJ, Zell T, Dileepan T, Cleary PP, Jenkins MK. Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells. Nature Immunology. 11: 83-9. PMID 19935657 DOI: 10.1038/Ni.1826  0.727
2007 Wilber A, Linehan JL, Tian X, Woll PS, Morris JK, Belur LR, McIvor RS, Kaufman DS. Efficient and stable transgene expression in human embryonic stem cells using transposon-mediated gene transfer. Stem Cells (Dayton, Ohio). 25: 2919-27. PMID 17673526 DOI: 10.1634/Stemcells.2007-0026  0.42
2007 Woll PS, Cameron C, Wilber A, Linehan JL, Kaufman DS. Cellular and genetic advances in analysis of hematopoietic development from human embryonic stem cells Blood Cells, Molecules, and Diseases. 38: 148. DOI: 10.1016/J.Bcmd.2006.10.069  0.351
2006 Tian X, Woll PS, Morris JK, Linehan JL, Kaufman DS. Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity. Stem Cells (Dayton, Ohio). 24: 1370-80. PMID 16456127 DOI: 10.1634/Stemcells.2005-0340  0.535
2006 Wilber A, Linehan JL, Tian X, McIvor RS, Kaufman DS. 95. Effective Genetic Engineering of Human Embryonic Stem Cells Using the Sleeping Beauty Transposon System Molecular Therapy. 13: S39. DOI: 10.1016/J.Ymthe.2006.08.114  0.43
2005 Schwartz RE, Linehan JL, Painschab MS, Hu WS, Verfaillie CM, Kaufman DS. Defined conditions for development of functional hepatic cells from human embryonic stem cells. Stem Cells and Development. 14: 643-55. PMID 16433619 DOI: 10.1089/Scd.2005.14.643  0.475
2005 Linehan JL, Tian X, Morris JK, Kaufman DS. Improved Analysis of Hematopoietic Engraftment by Non-Invasive In Vivo Bioluminescent Imaging of Transplanted Human Embryonic Stem Cell-Derived Hematopoietic Cells. Blood. 106: 1270-1270. DOI: 10.1182/Blood.V106.11.1270.1270  0.529
2004 Tian X, Morris JK, Linehan JL, Kaufman DS. Cytokine requirements differ for stroma and embryoid body-mediated hematopoiesis from human embryonic stem cells Experimental Hematology. 32: 1000-1009. PMID 15504555 DOI: 10.1016/J.Exphem.2004.06.013  0.472
2004 Lakshmipathy U, Pelacho B, Sudo K, Linehan JL, Coucouvanis E, Kaufman DS, Verfaillie CM. Efficient transfection of embryonic and adult stem cells. Stem Cells (Dayton, Ohio). 22: 531-43. PMID 15277699 DOI: 10.1634/Stemcells.22-4-531  0.422
2004 Kaufman DS, Woll PS, Martin CH, Linehan JL, Tian X. CD34+ Cells Derived from Human Embryonic Stem Cells Demonstrate Hematopoietic Stem Cell Potential In Vitro and in Vivo. Blood. 104: 564-564. DOI: 10.1182/Blood.V104.11.564.564  0.58
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