Jacob S. Yount, Ph.D. - Publications

Affiliations: 
2012- Microbial Infection and Immunity The Ohio State University College of Medicine 
Area:
Immunology, Microbiology Biology

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Qin Z, Bonifati S, St Gelais C, Li TW, Kim SH, Antonucci JM, Mahboubi B, Yount JS, Xiong Y, Kim B, Wu L. The dNTPase activity of SAMHD1 is important for its suppression of innate immune responses in differentiated monocytic cells. The Journal of Biological Chemistry. PMID 31914403 DOI: 10.1074/jbc.RA119.010360  0.52
2019 Zani A, Zhang L, McMichael TM, Kenney AD, Chemudupati M, Kwiek JJ, Liu SL, Yount JS. Interferon-Induced Transmembrane Proteins Inhibit Cell Fusion Mediated by Trophoblast Syncytins. The Journal of Biological Chemistry. PMID 31735710 DOI: 10.1074/jbc.AC119.010611  1
2019 Kenney AD, McMichael TM, Imas A, Chesarino NM, Zhang L, Dorn LE, Wu Q, Alfaour O, Amari F, Chen M, Zani A, Chemudupati M, Accornero F, Coppola V, Rajaram MVS, ... Yount JS, et al. IFITM3 protects the heart during influenza virus infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 31451661 DOI: 10.1073/pnas.1900784116  1
2018 Zani A, Yount JS. Antiviral Protection by IFITM3 In Vivo. Current Clinical Microbiology Reports. 5: 229-237. PMID 30662816 DOI: 10.1007/s40588-018-0103-0  0.52
2018 Chemudupati M, Kenney AD, Bonifati S, Zani A, McMichael TM, Wu L, Yount JS. From APOBEC to ZAP: Diverse mechanisms used by cellular restriction factors to inhibit virus infections. Biochimica Et Biophysica Acta. Molecular Cell Research. PMID 30290238 DOI: 10.1016/j.bbamcr.2018.09.012  1
2018 McMichael TM, Zhang Y, Kenney AD, Zhang L, Zani A, Lu M, Chemudupati M, Li J, Yount JS. IFITM3 Restricts Human Metapneumovirus Infection. The Journal of Infectious Diseases. PMID 29917090 DOI: 10.1093/infdis/jiy361  1
2018 Chen S, Bonifati S, Qin Z, St Gelais C, Kodigepalli KM, Barrett BS, Kim SH, Antonucci JM, Ladner KJ, Buzovetsky O, Knecht KM, Xiong Y, Yount JS, Guttridge DC, Santiago ML, et al. SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways. Proceedings of the National Academy of Sciences of the United States of America. PMID 29610295 DOI: 10.1073/pnas.1801213115  0.52
2017 McMichael TM, Zhang L, Chemudupati M, Hach JC, Kenney AD, Hang HC, Yount JS. The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity. The Journal of Biological Chemistry. PMID 29079573 DOI: 10.1074/jbc.M117.800482  1
2017 Kenney AD, Dowdle JA, Bozzacco L, McMichael TM, St Gelais C, Panfil AR, Sun Y, Schlesinger LS, Anderson MZ, Green PL, López CB, Rosenberg BR, Wu L, Yount JS. Human Genetic Determinants of Viral Diseases. Annual Review of Genetics. PMID 28853921 DOI: 10.1146/annurev-genet-120116-023425  1
2017 Chesarino NM, Compton AA, McMichael TM, Kenney AD, Zhang L, Soewarna V, Davis M, Schwartz O, Yount JS. IFITM3 requires an amphipathic helix for antiviral activity. Embo Reports. PMID 28835547 DOI: 10.15252/embr.201744100  1
2017 McMichael TM, Chemudupati M, Yount JS. A balancing act between IFITM3 and IRF3. Cellular & Molecular Immunology. PMID 28435158 DOI: 10.1038/cmi.2017.18  1
2017 Tsou LK, Yount JS, Hang HC. Epigallocatechin-3-gallate inhibits bacterial virulence and invasion of host cells. Bioorganic & Medicinal Chemistry. PMID 28325635 DOI: 10.1016/j.bmc.2017.03.023  0.56
2016 St Gelais C, Kim SH, Ding L, Yount J, Ivanov D, Spearman P, Wu L. A Putative Cyclin-binding Motif in Human SAMHD1 Contributes to Protein Phosphorylation, Localization and Stability. The Journal of Biological Chemistry. PMID 27815502 DOI: 10.1074/jbc.M116.753947  0.52
2016 Antonucci JM, St Gelais C, de Silva S, Yount JS, Tang C, Ji X, Shepard C, Xiong Y, Kim B, Wu L. SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity. Nature Medicine. 22: 1072-1074. PMID 27711056 DOI: 10.1038/nm.4163  1
2016 Compton AA, Roy N, Porrot F, Billet A, Casartelli N, Yount JS, Liang C, Schwartz O. Natural mutations in IFITM3 modulate post-translational regulation and toggle antiviral specificity. Embo Reports. PMID 27601221 DOI: 10.15252/embr.201642771  1
2016 Percher A, Ramakrishnan S, Thinon E, Yuan X, Yount JS, Hang HC. Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27044110 DOI: 10.1073/pnas.1602244113  1
2016 Tsou LK, Lara-Tejero M, RoseFigura J, Zhang ZJ, Wang YC, Yount JS, Lefebre M, Dossa PD, Kato J, Guan F, Lam W, Cheng YC, Galan JE, Hang HC. Anti-bacterial flavonoids from medicinal plants covalently inactivate type III protein secretion substrates. Journal of the American Chemical Society. PMID 26847396 DOI: 10.1021/jacs.5b11575  1
2015 Wang F, St Gelais C, de Silva S, Zhang H, Geng Y, Shepard C, Kim B, Yount JS, Wu L. Phosphorylation of mouse SAMHD1 regulates its restriction of human immunodeficiency virus type 1 infection, but not murine leukemia virus infection. Virology. 487: 273-284. PMID 26580513 DOI: 10.1016/j.virol.2015.10.024  1
2015 Chesarino NM, McMichael TM, Yount JS. E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3. Plos Pathogens. 11: e1005095. PMID 26263374 DOI: 10.1371/journal.ppat.1005095  1
2015 Melvin WJ, McMichael TM, Chesarino NM, Hach JC, Yount JS. IFITMs from Mycobacteria Confer Resistance to Influenza Virus When Expressed in Human Cells. Viruses. 7: 3035-52. PMID 26075508 DOI: 10.3390/v7062759  1
2014 Chesarino NM, McMichael TM, Yount JS. Regulation of the trafficking and antiviral activity of IFITM3 by post-translational modifications. Future Microbiology. 9: 1151-63. PMID 25405885 DOI: 10.2217/fmb.14.65  1
2014 Chesarino NM, Hach JC, Chen JL, Zaro BW, Rajaram MV, Turner J, Schlesinger LS, Pratt MR, Hang HC, Yount JS. Chemoproteomics reveals Toll-like receptor fatty acylation. Bmc Biology. 12: 91. PMID 25371237 DOI: 10.1186/s12915-014-0091-3  1
2014 Chesarino NM, McMichael TM, Hach JC, Yount JS. Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination. The Journal of Biological Chemistry. 289: 11986-92. PMID 24627473 DOI: 10.1074/jbc.M114.557694  1
2014 St Gelais C, de Silva S, Hach JC, White TE, Diaz-Griffero F, Yount JS, Wu L. Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1. Journal of Virology. 88: 5834-44. PMID 24623419 DOI: 10.1128/JVI.00155-14  1
2013 Hach JC, McMichael T, Chesarino NM, Yount JS. Palmitoylation on conserved and nonconserved cysteines of murine IFITM1 regulates its stability and anti-influenza A virus activity. Journal of Virology. 87: 9923-7. PMID 23804635 DOI: 10.1128/JVI.00621-13  1
2013 Yount JS, Zhang MM, Hang HC. Emerging roles for protein S-palmitoylation in immunity from chemical proteomics. Current Opinion in Chemical Biology. 17: 27-33. PMID 23332315 DOI: 10.1016/j.cbpa.2012.11.008  1
2012 Yount JS, Karssemeijer RA, Hang HC. S-palmitoylation and ubiquitination differentially regulate interferon-induced transmembrane protein 3 (IFITM3)-mediated resistance to influenza virus. The Journal of Biological Chemistry. 287: 19631-41. PMID 22511783 DOI: 10.1074/jbc.M112.362095  1
2012 Yount JS, Charron G, Hang HC. Bioorthogonal proteomics of 15-hexadecynyloxyacetic acid chemical reporter reveals preferential targeting of fatty acid modified proteins and biosynthetic enzymes. Bioorganic & Medicinal Chemistry. 20: 650-4. PMID 21524915 DOI: 10.1016/j.bmc.2011.03.062  1
2011 Yount JS, Zhang MM, Hang HC. Visualization and Identification of Fatty Acylated Proteins Using Chemical Reporters. Current Protocols in Chemical Biology. 3: 65-79. PMID 23061028 DOI: 10.1002/9780470559277.ch100225  0.56
2011 Moltedo B, Li W, Yount JS, Moran TM. Unique type I interferon responses determine the functional fate of migratory lung dendritic cells during influenza virus infection. Plos Pathogens. 7: e1002345. PMID 22072965 DOI: 10.1371/journal.ppat.1002345  1
2011 Cotter CR, Kim WK, Nguyen ML, Yount JS, López CB, Blaho JA, Moran TM. The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling. Journal of Virology. 85: 12662-72. PMID 21937652 DOI: 10.1128/JVI.05557-11  1
2011 Charron G, Tsou LK, Maguire W, Yount JS, Hang HC. Alkynyl-farnesol reporters for detection of protein S-prenylation in cells. Molecular Biosystems. 7: 67-73. PMID 21107478 DOI: 10.1039/c0mb00183j  1
2010 Yount JS, Moltedo B, Yang YY, Charron G, Moran TM, López CB, Hang HC. Palmitoylome profiling reveals S-palmitoylation-dependent antiviral activity of IFITM3. Nature Chemical Biology. 6: 610-4. PMID 20601941 DOI: 10.1038/nchembio.405  1
2010 Yount JS, Tsou LK, Dossa PD, Kullas AL, van der Velden AW, Hang HC. Visible fluorescence detection of type III protein secretion from bacterial pathogens. Journal of the American Chemical Society. 132: 8244-5. PMID 20504019 DOI: 10.1021/ja102257v  1
2010 Cotter CR, Nguyen ML, Yount JS, López CB, Blaho JA, Moran TM. The virion host shut-off (vhs) protein blocks a TLR-independent pathway of herpes simplex virus type 1 recognition in human and mouse dendritic cells. Plos One. 5: e8684. PMID 20174621 DOI: 10.1371/journal.pone.0008684  1
2009 Charron G, Zhang MM, Yount JS, Wilson J, Raghavan AS, Shamir E, Hang HC. Robust fluorescent detection of protein fatty-acylation with chemical reporters. Journal of the American Chemical Society. 131: 4967-75. PMID 19281244 DOI: 10.1021/ja810122f  1
2008 Friedman CS, O'Donnell MA, Legarda-Addison D, Ng A, Cárdenas WB, Yount JS, Moran TM, Basler CF, Komuro A, Horvath CM, Xavier R, Ting AT. The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response. Embo Reports. 9: 930-6. PMID 18636086 DOI: 10.1038/embor.2008.136  1
2008 Yount JS, Gitlin L, Moran TM, López CB. MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to Sendai Virus defective interfering particles. Journal of Immunology (Baltimore, Md. : 1950). 180: 4910-8. PMID 18354215  1
2007 Yount JS, Moran TM, López CB. Cytokine-independent upregulation of MDA5 in viral infection. Journal of Virology. 81: 7316-9. PMID 17475649 DOI: 10.1128/JVI.00545-07  1
2006 Yount JS, Kraus TA, Horvath CM, Moran TM, López CB. A novel role for viral-defective interfering particles in enhancing dendritic cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 177: 4503-13. PMID 16982887  1
2006 López CB, Yount JS, Hermesh T, Moran TM. Sendai virus infection induces efficient adaptive immunity independently of type I interferons. Journal of Virology. 80: 4538-45. PMID 16611914 DOI: 10.1128/JVI.80.9.4538-4545.2006  1
2006 López CB, Yount JS, Moran TM. Toll-like receptor-independent triggering of dendritic cell maturation by viruses. Journal of Virology. 80: 3128-34. PMID 16537581 DOI: 10.1128/JVI.80.7.3128-3134.2006  1
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