Michael G. Caparon - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Microbiology Biology

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Year Citation  Score
2023 Caparon M, Xu W, Bradstreet T, Zou Z, Hickerson S, Zhou Y, He H, Edelson B. Reprogramming Short-Chain Fatty Acid Metabolism Mitigates Tissue Damage for Streptococcus pyogenes Necrotizing Skin Infection. Research Square. PMID 38196634 DOI: 10.21203/rs.3.rs-3689163/v1  0.3
2023 Molina JJ, Kohler KN, Gager C, Andersen MJ, Wongso E, Lucas ER, Paik A, Xu W, Donahue DL, Bergeron K, Klim A, Caparon MG, Hultgren SJ, Desai A, Ploplis VA, et al. Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI. Research Square. PMID 37790429 DOI: 10.21203/rs.3.rs-3263501/v1  0.324
2019 Walker JN, Flores-Mireles AL, Lynch AJL, Pinkner C, Caparon MG, Hultgren SJ, Desai A. High-resolution imaging reveals microbial biofilms on patient urinary catheters despite antibiotic administration. World Journal of Urology. PMID 31792577 DOI: 10.1007/S00345-019-03027-8  0.389
2019 Yu L, O'Brien VP, Livny J, Dorsey D, Bandyopadhyay N, Colonna M, Caparon MG, Roberson ED, Hultgren SJ, Hannan TJ. Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence. Elife. 8. PMID 31429405 DOI: 10.7554/Elife.46677  0.395
2019 Walker EA, Port GC, Caparon MG, Janowiak BE. Glutathione Synthesis Contributes to Virulence of in a Murine Model of Sepsis. Journal of Bacteriology. PMID 31331978 DOI: 10.1128/Jb.00367-19  0.419
2019 Yu L, O'Brien VP, Livny J, Dorsey D, Bandyopadhyay N, Colonna M, Caparon MG, Roberson ED, Hultgren SJ, Hannan TJ. Author response: Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence Elife. DOI: 10.7554/Elife.46677.027  0.312
2018 Paluscio E, Watson ME, Caparon MG. CcpA Coordinates Growth/Damage Balance for Streptococcus pyogenes Pathogenesis. Scientific Reports. 8: 14254. PMID 30250043 DOI: 10.1038/S41598-018-32558-0  0.391
2017 Xu W, Flores-Mireles AL, Cusumano ZT, Takagi E, Hultgren SJ, Caparon MG. Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection. Npj Biofilms and Microbiomes. 3: 28. PMID 29134108 DOI: 10.1038/s41522-017-0036-z  0.786
2017 Walker JN, Flores-Mireles AL, Pinkner CL, Schreiber HL, Joens MS, Park AM, Potretzke AM, Bauman TM, Pinkner JS, Fitzpatrick JAJ, Desai A, Caparon MG, Hultgren SJ. Catheterization alters bladder ecology to potentiate Staphylococcus aureus infection of the urinary tract. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973850 DOI: 10.1073/Pnas.1707572114  0.459
2017 Port GC, Cusumano ZT, Tumminello PR, Caparon MG. SpxA1 and SpxA2 Act Coordinately To Fine-Tune Stress Responses and Virulence in Streptococcus pyogenes. Mbio. 8. PMID 28351920 DOI: 10.1128/Mbio.00288-17  0.775
2016 Flores-Mireles AL, Walker JN, Potretzke A, Schreiber HL, Pinkner JS, Bauman TM, Park AM, Desai A, Hultgren SJ, Caparon MG. Antibody-Based Therapy for Enterococcal Catheter-Associated Urinary Tract Infections. Mbio. 7. PMID 27795399 DOI: 10.1128/Mbio.01653-16  0.434
2016 Chandrasekaran S, Caparon MG. The NADase-Negative Variant of the Streptococcus pyogenes Toxin NAD+ Glycohydrolase Induces JNK1-Mediated Programmed Cellular Necrosis. Mbio. 7. PMID 26838722 DOI: 10.1128/Mbio.02215-15  0.618
2016 Flores-Mireles AL, Walker JN, Bauman TM, Potretzke AM, Schreiber HL, Park AM, Pinkner JS, Caparon MG, Hultgren SJ, Desai A. Fibrinogen release and deposition on urinary catheters placed during urologic procedures. The Journal of Urology. PMID 26827873 DOI: 10.1016/J.Juro.2016.01.100  0.374
2015 Mozola CC, Caparon MG. Dual modes of membrane binding direct pore formation by Streptolysin O. Molecular Microbiology. 97: 1036-50. PMID 26059530 DOI: 10.1111/Mmi.13085  0.442
2015 Flores-Mireles AL, Walker JN, Caparon M, Hultgren SJ. Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nature Reviews. Microbiology. 13: 269-84. PMID 25853778 DOI: 10.1038/Nrmicro3432  0.385
2015 Chandrasekaran S, Caparon MG. The Streptococcus pyogenes NAD(+) glycohydrolase modulates epithelial cell PARylation and HMGB1 release. Cellular Microbiology. 17: 1376-90. PMID 25818652 DOI: 10.1111/Cmi.12442  0.594
2015 Cusumano ZT, Caparon MG. Citrulline protects Streptococcus pyogenes from acid stress using the arginine deiminase pathway and the F1Fo-ATPase. Journal of Bacteriology. 197: 1288-96. PMID 25645553 DOI: 10.1128/Jb.02517-14  0.774
2015 Paluscio E, Caparon MG. Streptococcus pyogenes malate degradation pathway links pH regulation and virulence. Infection and Immunity. 83: 1162-71. PMID 25583521 DOI: 10.1128/Iai.02814-14  0.467
2014 Flores-Mireles AL, Pinkner JS, Caparon MG, Hultgren SJ. EbpA vaccine antibodies block binding of Enterococcus faecalis to fibrinogen to prevent catheter-associated bladder infection in mice. Science Translational Medicine. 6: 254ra127. PMID 25232179 DOI: 10.1126/Scitranslmed.3009384  0.419
2014 Mozola CC, Magassa N, Caparon MG. A novel cholesterol-insensitive mode of membrane binding promotes cytolysin-mediated translocation by Streptolysin O. Molecular Microbiology. 94: 675-87. PMID 25196983 DOI: 10.1111/Mmi.12786  0.749
2014 Port GC, Vega LA, Nylander AB, Caparon MG. Streptococcus pyogenes polymyxin B-resistant mutants display enhanced ExPortal integrity. Journal of Bacteriology. 196: 2563-77. PMID 24794568 DOI: 10.1128/Jb.01596-14  0.686
2014 Cusumano ZT, Watson ME, Caparon MG. Streptococcus pyogenes arginine and citrulline catabolism promotes infection and modulates innate immunity. Infection and Immunity. 82: 233-42. PMID 24144727 DOI: 10.1128/Iai.00916-13  0.797
2013 Kandaswamy K, Liew TH, Wang CY, Huston-Warren E, Meyer-Hoffert U, Hultenby K, Schröder JM, Caparon MG, Normark S, Henriques-Normark B, Hultgren SJ, Kline KA. Focal targeting by human β-defensin 2 disrupts localized virulence factor assembly sites in Enterococcus faecalis. Proceedings of the National Academy of Sciences of the United States of America. 110: 20230-5. PMID 24191013 DOI: 10.1073/Pnas.1319066110  0.368
2013 Vega LA, Port GC, Caparon MG. An association between peptidoglycan synthesis and organization of the Streptococcus pyogenes ExPortal. Mbio. 4: e00485-13. PMID 24065630 DOI: 10.1128/Mbio.00485-13  0.687
2013 Port GC, Paluscio E, Caparon MG. Complete Genome Sequence of emm Type 14 Streptococcus pyogenes Strain HSC5. Genome Announcements. 1. PMID 23950122 DOI: 10.1128/Genomea.00612-13  0.322
2013 Nielsen HV, Flores-Mireles AL, Kau AL, Kline KA, Pinkner JS, Neiers F, Normark S, Henriques-Normark B, Caparon MG, Hultgren SJ. Pilin and sortase residues critical for endocarditis- and biofilm-associated pilus biogenesis in Enterococcus faecalis. Journal of Bacteriology. 195: 4484-95. PMID 23913319 DOI: 10.1128/Jb.00451-13  0.399
2013 Chandrasekaran S, Ghosh J, Port GC, Koh EI, Caparon MG. Analysis of polymorphic residues reveals distinct enzymatic and cytotoxic activities of the Streptococcus pyogenes NAD+ glycohydrolase. The Journal of Biological Chemistry. 288: 20064-75. PMID 23689507 DOI: 10.1074/Jbc.M113.481556  0.59
2013 Watson ME, Nielsen HV, Hultgren SJ, Caparon MG. Murine vaginal colonization model for investigating asymptomatic mucosal carriage of Streptococcus pyogenes. Infection and Immunity. 81: 1606-17. PMID 23460515 DOI: 10.1128/Iai.00021-13  0.414
2013 Cusumano Z, Caparon M. Adaptive evolution of the Streptococcus pyogenes regulatory aldolase LacD.1. Journal of Bacteriology. 195: 1294-304. PMID 23316044 DOI: 10.1128/Jb.01997-12  0.781
2013 Guiton PS, Hannan TJ, Ford B, Caparon MG, Hultgren SJ. Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urinary tract infections. Infection and Immunity. 81: 329-39. PMID 23132492 DOI: 10.1128/Iai.00856-12  0.784
2012 Nielsen HV, Guiton PS, Kline KA, Port GC, Pinkner JS, Neiers F, Normark S, Henriques-Normark B, Caparon MG, Hultgren SJ. The metal ion-dependent adhesion site motif of the Enterococcus faecalis EbpA pilin mediates pilus function in catheter-associated urinary tract infection. Mbio. 3: e00177-12. PMID 22829678 DOI: 10.1128/Mbio.00177-12  0.808
2012 Vega LA, Caparon MG. Cationic antimicrobial peptides disrupt the Streptococcus pyogenes ExPortal. Molecular Microbiology. 85: 1119-32. PMID 22780862 DOI: 10.1111/J.1365-2958.2012.08163.X  0.695
2012 Guiton PS, Cusumano CK, Kline KA, Dodson KW, Han Z, Janetka JW, Henderson JP, Caparon MG, Hultgren SJ. Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice. Antimicrobial Agents and Chemotherapy. 56: 4738-45. PMID 22733070 DOI: 10.1128/Aac.00447-12  0.793
2011 Sperry JB, Smith CL, Caparon MG, Ellenberger T, Gross ML. Mapping the protein-protein interface between a toxin and its cognate antitoxin from the bacterial pathogen Streptococcus pyogenes. Biochemistry. 50: 4038-45. PMID 21466233 DOI: 10.1021/Bi200244K  0.319
2011 Smith CL, Ghosh J, Elam JS, Pinkner JS, Hultgren SJ, Caparon MG, Ellenberger T. Structural basis of Streptococcus pyogenes immunity to its NAD+ glycohydrolase toxin. Structure (London, England : 1993). 19: 192-202. PMID 21300288 DOI: 10.1016/J.Str.2010.12.013  0.394
2011 Kietzman CC, Caparon MG. Distinct time-resolved roles for two catabolite-sensing pathways during Streptococcus pyogenes infection. Infection and Immunity. 79: 812-21. PMID 21098101 DOI: 10.1128/Iai.01026-10  0.796
2010 Guiton PS, Hung CS, Hancock LE, Caparon MG, Hultgren SJ. Enterococcal biofilm formation and virulence in an optimized murine model of foreign body-associated urinary tract infections. Infection and Immunity. 78: 4166-75. PMID 20696830 DOI: 10.1128/Iai.00711-10  0.798
2010 Riddle DJ, Bessen DE, Caparon MG. Variation in Streptococcus pyogenes NAD+ glycohydrolase is associated with tissue tropism. Journal of Bacteriology. 192: 3735-46. PMID 20494994 DOI: 10.1128/Jb.00234-10  0.414
2010 Kang SO, Caparon MG, Cho KH. Virulence gene regulation by CvfA, a putative RNase: the CvfA-enolase complex in Streptococcus pyogenes links nutritional stress, growth-phase control, and virulence gene expression. Infection and Immunity. 78: 2754-67. PMID 20385762 DOI: 10.1128/Iai.01370-09  0.437
2010 Kline KA, Dodson KW, Caparon MG, Hultgren SJ. A tale of two pili: assembly and function of pili in bacteria. Trends in Microbiology. 18: 224-32. PMID 20378353 DOI: 10.1016/J.Tim.2010.03.002  0.362
2010 Magassa N, Chandrasekaran S, Caparon MG. Streptococcus pyogenes cytolysin-mediated translocation does not require pore formation by streptolysin O. Embo Reports. 11: 400-5. PMID 20339385 DOI: 10.1038/Embor.2010.37  0.777
2010 Kline KA, Ingersoll MA, Nielsen HV, Sakinc T, Henriques-Normark B, Gatermann S, Caparon MG, Hultgren SJ. Characterization of a novel murine model of Staphylococcus saprophyticus urinary tract infection reveals roles for Ssp and SdrI in virulence. Infection and Immunity. 78: 1943-51. PMID 20176795 DOI: 10.1128/Iai.01235-09  0.427
2010 Ghosh J, Anderson PJ, Chandrasekaran S, Caparon MG. Characterization of Streptococcus pyogenes beta-NAD+ glycohydrolase: re-evaluation of enzymatic properties associated with pathogenesis. The Journal of Biological Chemistry. 285: 5683-94. PMID 20018886 DOI: 10.1074/Jbc.M109.070300  0.564
2010 Kietzman CC, Caparon MG. CcpA and LacD.1 affect temporal regulation of Streptococcus pyogenes virulence genes. Infection and Immunity. 78: 241-52. PMID 19841076 DOI: 10.1128/Iai.00746-09  0.795
2009 Lin A, Loughman JA, Zinselmeyer BH, Miller MJ, Caparon MG. Streptolysin S inhibits neutrophil recruitment during the early stages of Streptococcus pyogenes infection. Infection and Immunity. 77: 5190-201. PMID 19687200 DOI: 10.1128/Iai.00420-09  0.802
2009 Guiton PS, Hung CS, Kline KA, Roth R, Kau AL, Hayes E, Heuser J, Dodson KW, Caparon MG, Hultgren SJ. Contribution of autolysin and Sortase a during Enterococcus faecalis DNA-dependent biofilm development. Infection and Immunity. 77: 3626-38. PMID 19528211 DOI: 10.1128/Iai.00219-09  0.776
2009 Weston BF, Brenot A, Caparon MG. The metal homeostasis protein, Lsp, of Streptococcus pyogenes is necessary for acquisition of zinc and virulence. Infection and Immunity. 77: 2840-8. PMID 19398546 DOI: 10.1128/Iai.01299-08  0.387
2009 Kline KA, Kau AL, Chen SL, Lim A, Pinkner JS, Rosch J, Nallapareddy SR, Murray BE, Henriques-Normark B, Beatty W, Caparon MG, Hultgren SJ. Mechanism for sortase localization and the role of sortase localization in efficient pilus assembly in Enterococcus faecalis. Journal of Bacteriology. 191: 3237-47. PMID 19286802 DOI: 10.1128/Jb.01837-08  0.663
2008 Cho KH, Caparon MG. tRNA modification by GidA/MnmE is necessary for Streptococcus pyogenes virulence: a new strategy to make live attenuated strains. Infection and Immunity. 76: 3176-86. PMID 18426891 DOI: 10.1128/Iai.01721-07  0.427
2008 Rosch JW, Vega LA, Beyer JM, Lin A, Caparon MG. The signal recognition particle pathway is required for virulence in Streptococcus pyogenes. Infection and Immunity. 76: 2612-9. PMID 18411293 DOI: 10.1128/Iai.00239-07  0.772
2007 Cole JN, Aquilina JA, Hains PG, Henningham A, Sriprakash KS, Caparon MG, Nizet V, Kotb M, Cordwell SJ, Djordjevic SP, Walker MJ. Role of group A Streptococcus HtrA in the maturation of SpeB protease. Proteomics. 7: 4488-98. PMID 18072207 DOI: 10.1002/Pmic.200700626  0.365
2007 Loughman JA, Caparon MG. Comparative functional analysis of the lac operons in Streptococcus pyogenes. Molecular Microbiology. 64: 269-80. PMID 17371500 DOI: 10.1111/J.1365-2958.2007.05663.X  0.8
2007 Brenot A, Weston BF, Caparon MG. A PerR-regulated metal transporter (PmtA) is an interface between oxidative stress and metal homeostasis in Streptococcus pyogenes. Molecular Microbiology. 63: 1185-96. PMID 17238923 DOI: 10.1111/J.1365-2958.2006.05577.X  0.358
2007 Rosch JW, Hsu FF, Caparon MG. Anionic lipids enriched at the ExPortal of Streptococcus pyogenes. Journal of Bacteriology. 189: 801-6. PMID 17142392 DOI: 10.1128/Jb.01549-06  0.635
2007 Loughman JA, Caparon MG. Contribution of invariant residues to the function of Rgg family transcription regulators. Journal of Bacteriology. 189: 650-5. PMID 17098902 DOI: 10.1128/Jb.01437-06  0.781
2006 Loughman JA, Caparon MG. A novel adaptation of aldolase regulates virulence in Streptococcus pyogenes. The Embo Journal. 25: 5414-22. PMID 17066081 DOI: 10.1038/Sj.Emboj.7601393  0.801
2006 Ghosh J, Caparon MG. Specificity of Streptococcus pyogenes NAD(+) glycohydrolase in cytolysin-mediated translocation. Molecular Microbiology. 62: 1203-14. PMID 17042787 DOI: 10.1111/J.1365-2958.2006.05430.X  0.446
2006 Loughman JA, Caparon M. Regulation of SpeB in Streptococcus pyogenes by pH and NaCl: a model for in vivo gene expression. Journal of Bacteriology. 188: 399-408. PMID 16385029 DOI: 10.1128/Jb.188.2.399-408.2006  0.792
2005 Meehl MA, Pinkner JS, Anderson PJ, Hultgren SJ, Caparon MG. A novel endogenous inhibitor of the secreted streptococcal NAD-glycohydrolase. Plos Pathogens. 1: e35. PMID 16333395 DOI: 10.1371/Journal.Ppat.0010035  0.803
2005 Rosch JW, Caparon MG. The ExPortal: an organelle dedicated to the biogenesis of secreted proteins in Streptococcus pyogenes. Molecular Microbiology. 58: 959-68. PMID 16262783 DOI: 10.1111/J.1365-2958.2005.04887.X  0.664
2005 Cho KH, Caparon MG. Patterns of virulence gene expression differ between biofilm and tissue communities of Streptococcus pyogenes. Molecular Microbiology. 57: 1545-56. PMID 16135223 DOI: 10.1111/J.1365-2958.2005.04786.X  0.445
2005 Kau AL, Martin SM, Lyon W, Hayes E, Caparon MG, Hultgren SJ. Enterococcus faecalis tropism for the kidneys in the urinary tract of C57BL/6J mice. Infection and Immunity. 73: 2461-8. PMID 15784592 DOI: 10.1128/Iai.73.4.2461-2468.2005  0.37
2005 Brenot A, King KY, Caparon MG. The PerR regulon in peroxide resistance and virulence of Streptococcus pyogenes. Molecular Microbiology. 55: 221-34. PMID 15612930 DOI: 10.1111/J.1365-2958.2004.04370.X  0.448
2004 Meehl MA, Caparon MG. Specificity of streptolysin O in cytolysin-mediated translocation. Molecular Microbiology. 52: 1665-76. PMID 15186416 DOI: 10.1111/J.1365-2958.2004.04082.X  0.798
2004 Rosch J, Caparon M. A microdomain for protein secretion in Gram-positive bacteria. Science (New York, N.Y.). 304: 1513-5. PMID 15178803 DOI: 10.1126/Science.1097404  0.67
2004 Nyberg P, Sakai T, Cho KH, Caparon MG, Fässler R, Björck L. Interactions with fibronectin attenuate the virulence of Streptococcus pyogenes. The Embo Journal. 23: 2166-74. PMID 15103329 DOI: 10.1038/Sj.Emboj.7600214  0.41
2004 Lyon WR, Caparon MG. Role for serine protease HtrA (DegP) of Streptococcus pyogenes in the biogenesis of virulence factors SpeB and the hemolysin streptolysin S. Infection and Immunity. 72: 1618-25. PMID 14977969 DOI: 10.1128/Iai.72.3.1618-1625.2004  0.472
2004 Brenot A, King KY, Janowiak B, Griffith O, Caparon MG. Contribution of Glutathione Peroxidase to the Virulence of Streptococcus pyogenes Infection and Immunity. 72: 408-413. PMID 14688122 DOI: 10.1128/Iai.72.1.408-413.2004  0.415
2003 Neely MN, Lyon WR, Runft DL, Caparon M. Role of RopB in growth phase expression of the SpeB cysteine protease of Streptococcus pyogenes. Journal of Bacteriology. 185: 5166-74. PMID 12923089 DOI: 10.1128/Jb.185.17.5166-5174.2003  0.364
2003 Lyon WR, Caparon MG. Trigger factor-mediated prolyl isomerization influences maturation of the Streptococcus pyogenes cysteine protease. Journal of Bacteriology. 185: 3661-7. PMID 12775704 DOI: 10.1128/Jb.185.12.3661-3667.2003  0.408
2002 Neely MN, Pfeifer JD, Caparon M. Streptococcus-zebrafish model of bacterial pathogenesis. Infection and Immunity. 70: 3904-14. PMID 12065534 DOI: 10.1128/Iai.70.7.3904-3914.2002  0.385
2002 Gibson CM, Caparon MG. Alkaline phosphatase reporter transposon for identification of genes encoding secreted proteins in gram-positive microorganisms. Applied and Environmental Microbiology. 68: 928-32. PMID 11823238 DOI: 10.1128/Aem.68.02.928-932.2002  0.409
2001 Lyon WR, Madden JC, Levin JC, Stein JL, Caparon MG. Mutation of luxS affects growth and virulence factor expression in Streptococcus pyogenes Molecular Microbiology. 42: 145-157. PMID 11679074 DOI: 10.1046/J.1365-2958.2001.02616.X  0.512
2001 Francis KP, Yu J, Bellinger-Kawahara C, Joh D, Hawkinson MJ, Xiao G, Purchio TF, Caparon MG, Lipsitch M, Contag PR. Visualizing pneumococcal infections in the lungs of live mice using bioluminescent Streptococcus pneumoniae transformed with a novel gram-positive lux transposon Infection and Immunity. 69: 3350-3358. PMID 11292758 DOI: 10.1128/Iai.69.5.3350-3358.2001  0.388
2001 Madden JC, Ruiz N, Caparon M. Cytolysin-mediated translocation (CMT): A functional equivalent of type III secretion in Gram-positive bacteria Cell. 104: 143-152. PMID 11163247 DOI: 10.1016/S0092-8674(01)00198-2  0.423
2000 King KY, Horenstein JA, Caparon MG. Aerotolerance and peroxide resistance in peroxidase and PerR mutants of Streptococcus pyogenes Journal of Bacteriology. 182: 5290-5299. PMID 10986229 DOI: 10.1128/Jb.182.19.5290-5299.2000  0.38
2000 Granok AB, Parsonage D, Ross RP, Caparon MG. The RofA binding site in Streptococcus pyogenes is utilized in multiple transcriptional pathways Journal of Bacteriology. 182: 1529-1540. PMID 10692357 DOI: 10.1128/Jb.182.6.1529-1540.2000  0.406
2000 Gibson CM, Mallett TC, Claiborne A, Caparon MG. Contribution of NADH oxidase to aerobic metabolism of Streptococcus pyogenes Journal of Bacteriology. 182: 448-455. PMID 10629192 DOI: 10.1128/Jb.182.2.448-455.2000  0.384
1998 Okada N, Tatsuno L, Hanski E, Caparon M, Sasakawa C. Streptococcus pyogenes protein F promotes invasion of HeLa cells. Microbiology (Reading, England). 144: 3079-3086. PMID 9846743 DOI: 10.1099/00221287-144-11-3079  0.378
1998 Lyon WR, Gibson CM, Caparon MG. A role for Trigger Factor and an Rgg-like regulator in the transcription, secretion and processing of the cysteine proteinase of Streptococcus pyogenes Embo Journal. 17: 6263-6275. PMID 9799235 DOI: 10.1093/Emboj/17.21.6263  0.474
1998 Ruiz N, Wang B, Pentland A, Caparon M. Streptolysin O and adherence synergistically modulate proinflammatory responses of keratinocytes to group A streptococci. Molecular Microbiology. 27: 337-46. PMID 9484889 DOI: 10.1046/J.1365-2958.1998.00681.X  0.409
1997 Okada N, Watarai M, Ozeri V, Hanski E, Caparon M, Sasakawa C. A matrix form of fibronectin mediates enhanced binding of Streptococcus pyogenes to host tissue. The Journal of Biological Chemistry. 272: 26978-84. PMID 9341135 DOI: 10.1074/Jbc.272.43.26978  0.361
1997 Fogg GC, Caparon MG. Constitutive expression of fibronectin binding in Streptococcus pyogenes as a result of anaerobic activation of rofA Journal of Bacteriology. 179: 6172-6180. PMID 9324268 DOI: 10.1128/Jb.179.19.6172-6180.1997  0.414
1997 Wang B, Ruiz N, Pentland A, Caparon M. Keratinocyte proinflammatory responses to adherent and nonadherent group A streptococci. Infection and Immunity. 65: 2119-26. PMID 9169741 DOI: 10.1128/Iai.65.6.2119-2126.1997  0.378
1996 Jaffe J, Natanson-Yaron S, Caparon MG, Hanski E. Protein F2, a novel fibronectin-binding protein from Streptococcus pyogenes, possesses two binding domains Molecular Microbiology. 21: 373-384. PMID 8858591 DOI: 10.1046/J.1365-2958.1996.6331356.X  0.315
1996 Gibson CM, Caparon MG. Insertional inactivation of Streptococcus pyogenes sod suggests that prtF is regulated in response to a superoxide signal Journal of Bacteriology. 178: 4688-4695. PMID 8755901 DOI: 10.1128/Jb.178.15.4688-4695.1996  0.411
1996 Ozeri V, Tovi A, Burstein I, Natanson-Yaron S, Caparon MG, Yamada KM, Akiyama SK, Vlodavsky I, Hanski E. A two-domain mechanism for group A streptococcal adherence through protein F to the extracellular matrix Embo Journal. 15: 989-998. PMID 8605894 DOI: 10.1002/J.1460-2075.1996.Tb00435.X  0.333
1995 Kihlberg BM, Cooney J, Caparon MG, Olsén A, Björck L. Biological properties of a Streptococcus pyogenes mutant generated by Tn916 insertion in mga Microbial Pathogenesis. 19: 299-315. PMID 8778565 DOI: 10.1016/S0882-4010(96)80003-9  0.418
1995 Okada N, Liszewski MK, Atkinson JP, Caparon M. Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus. Proceedings of the National Academy of Sciences of the United States of America. 92: 2489-93. PMID 7708671 DOI: 10.1073/Pnas.92.7.2489  0.37
1995 Falk P, Borén T, Haslam D, Caparon M. Bacterial adhesion and colonization assays. Methods in Cell Biology. 45: 165-92. PMID 7707985 DOI: 10.1016/S0091-679X(08)61851-8  0.324
1995 Natanson S, Sela S, Moses AE, Musser JM, Caparon MG, Hanski E. Distribution of fibronectin-binding proteins among group a streptococci of different m types Journal of Infectious Diseases. 171: 871-878. PMID 7706813 DOI: 10.1093/Infdis/171.4.871  0.306
1995 Perez-Casal J, Okada N, Caparon MG, Scott JR. Role of the conserved C-repeat region of the M protein of Streptococcus pyogenes Molecular Microbiology. 15: 907-916. PMID 7596292 DOI: 10.1111/J.1365-2958.1995.Tb02360.X  0.353
1995 Hanski E, Fogg G, Tovi A, Okada N, Burstein I, Caparon M. Molecular analysis of Streptococcus pyogenes adhesion. Methods in Enzymology. 253: 269-305. PMID 7476392 DOI: 10.1016/S0076-6879(95)53025-8  0.423
1994 Fogg GC, Gibson CM, Caparon MG. The identification of rofA, a positive-acting regulatory component of prtF expression: Use of an mγδ-based shuttle mutagenesis strategy in Streptococcus pyogenes Molecular Microbiology. 11: 671-684. PMID 8196542 DOI: 10.1111/J.1365-2958.1994.Tb00345.X  0.429
1994 Okada N, Pentland AP, Falk P, Caparon MG. M protein and protein F act as important determinants of cell-specific tropism of Streptococcus pyogenes in skin tissue. The Journal of Clinical Investigation. 94: 965-77. PMID 8083381 DOI: 10.1172/Jci117463  0.378
1994 VanHeyningen T, Fogg G, Yates D, Hanski E, Caparon M. Adherence and fibronectin binding are environmentally regulated in the group A streptococci. Molecular Microbiology. 9: 1213-22. PMID 7934934 DOI: 10.1111/J.1365-2958.1993.Tb01250.X  0.4
1993 Okada N, Geist RT, Caparon MG. Positive transcriptional control of mry regulates virulence in the group A streptococcus Molecular Microbiology. 7: 893-903. PMID 8483419 DOI: 10.1111/J.1365-2958.1993.Tb01180.X  0.401
1993 Geist RT, Okada N, Caparon MG. Analysis of Streptococcus pyogenes promoters by using novel Tn916-based shuttle vectors for the construction of transcriptional fusions to chloramphenicol acetyltransferase Journal of Bacteriology. 175: 7561-7570. PMID 8244925 DOI: 10.1128/Jb.175.23.7561-7570.1993  0.412
1993 Hultgren SJ, Abraham S, Caparon M, Falk P, Geme JWS, Normark S. Pilus and nonpilus bacterial adhesins: Assembly and function in cell recognition Cell. 73: 887-901. PMID 8098994 DOI: 10.1016/0092-8674(93)90269-V  0.317
1993 Sela S, Aviv A, Tovi A, Burstein I, Caparon MG, Hanski E. Protein F: An adhesin of Streptococcus pyogenes binds fibronectin via two distinct domains Molecular Microbiology. 10: 1049-1055. PMID 7934855 DOI: 10.1111/J.1365-2958.1993.Tb00975.X  0.322
1993 Olsén AN, Hanski E, Normakr S, Caparon MG. Molecular characterization of fibronectin binding proteins in bacteria Journal of Microbiological Methods. 18: 213-226. DOI: 10.1016/0167-7012(93)90037-I  0.318
1992 Caparon MG, Geist RT, Perez-Casal J, Scott JR. Environmental regulation of virulence in group A streptococci: Transcription of the gene encoding M protein is stimulated by carbon dioxide Journal of Bacteriology. 174: 5693-5701. PMID 1512202 DOI: 10.1128/Jb.174.17.5693-5701.1992  0.39
1992 Perez-Casal J, Caparon MG, Scott JR. Introduction of the emm6 gene into an emm-deleted strain of Streptococcus pyogenes restores its ability to resist phagocytosis Research in Microbiology. 143: 549-558. PMID 1475516 DOI: 10.1016/0923-2508(92)90112-2  0.332
1992 Hanski E, Horwitz PA, Caparon MG. Expression of protein F, the fibronectin-binding protein of Streptococcus pyogenes JRS4, in heterologous streptococcal and enterococcal strains promotes their adherence to respiratory epithelial cells Infection and Immunity. 60: 5119-5125. PMID 1452345 DOI: 10.1128/Iai.60.12.5119-5125.1992  0.341
1992 Hanski E, Caparon M. Protein F, a fibronectin-binding protein, is an adhesin of the group A streptococcus Streptococcus pyogenes. Proceedings of the National Academy of Sciences of the United States of America. 89: 6172-6. PMID 1385871 DOI: 10.1073/Pnas.89.13.6172  0.359
1991 Perez-Casal J, Caparon MG, Scott JR. Mry, a trans-acting positive regulator of the M protein gene of Streptococcus pyogenes with similarity to the receptor proteins of two-component regulatory systems Journal of Bacteriology. 173: 2617-2624. PMID 1849511 DOI: 10.1128/Jb.173.8.2617-2624.1991  0.37
1991 Caparon MG, Scott JR. [26] Genetic manipulation of pathogenic streptococci Methods in Enzymology. 204: 556-586. PMID 1658571 DOI: 10.1016/0076-6879(91)04028-M  0.337
1988 Scott JR, Kirchman PA, Caparon MG. An intermediate in transposition of the conjugative transposon Tn916 Proceedings of the National Academy of Sciences of the United States of America. 85: 4809-4813. PMID 2838847 DOI: 10.1073/Pnas.85.13.4809  0.307
1987 Caparon MG, Scott JR. Identification of a gene that regulates expression of M protein, the major virulence determinant of group A streptococci Proceedings of the National Academy of Sciences of the United States of America. 84: 8677-8681. PMID 2446327 DOI: 10.1073/Pnas.84.23.8677  0.38
Low-probability matches (unlikely to be authored by this person)
1989 Caparon MG, Scott JR. Excision and insertion of the conjugative transposon Tn916 involves a novel recombination mechanism Cell. 59: 1027-1034. PMID 2557157 DOI: 10.1016/0092-8674(89)90759-9  0.293
1991 Caparon MG, Stephens DS, Olsen A, Scott JR. Role of M protein in adherence of group A streptococci Infection and Immunity. 59: 1811-1817. PMID 2019444 DOI: 10.1128/Iai.59.5.1811-1817.1991  0.292
2024 Zou Z, Obernuefemann CLP, Singh P, Pinkner JS, Xu W, Nye TM, Dodson KW, Almqvist F, Hultgren SJ, Caparon MG. Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat skin and soft tissue infection. Biorxiv : the Preprint Server For Biology. PMID 38260261 DOI: 10.1101/2024.01.02.573960  0.287
1995 Scott JR, Cleary P, Caparon MG, Kehoe M, Heden L, Musser JM, Hollingshead S, Podbielski A. New name for the positive regulator of the M protein of group A Streptococcus [1] Molecular Microbiology. 17: 799. PMID 8801432 DOI: 10.1111/J.1365-2958.1995.Mmi_17040799.X  0.285
2016 Carey AJ, Weinberg JB, Dawid SR, Venturini C, Lam AK, Nizet V, Caparon MG, Walker MJ, Watson ME, Ulett GC. Interleukin-17A Contributes to the Control of Streptococcus pyogenes Colonization and Inflammation of the Female Genital Tract. Scientific Reports. 6: 26836. PMID 27241677 DOI: 10.1038/Srep26836  0.274
2023 Merriman JA, Xu W, Caparon MG. Central carbon flux controls growth/damage balance for Streptococcus pyogenes. Plos Pathogens. 19: e1011481. PMID 37384800 DOI: 10.1371/journal.ppat.1011481  0.27
2015 Port GC, Paluscio E, Caparon MG. Complete Genome Sequences of emm6 Streptococcus pyogenes JRS4 and Parental Strain D471. Genome Announcements. 3. PMID 26139722 DOI: 10.1128/Genomea.00725-15  0.253
2017 Bauman TM, Potretzke AM, Flores-Mireles AL, Walker JN, Park AM, Schreiber HL, Pinkner JS, Caparon MG, Hultgren SJ, Desai A. MP23-19 FIBRINOGEN DEPOSITS ON URINARY CATHETERS IN A TIME-DEPENDENT MATTER AND CO-LOCALIZES WITH E. FAECALIS IN PATIENTS WITH POSITIVE E. FAECALIS URINE CULTURES Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.747  0.247
2017 Cervantes-Barragan L, Chai JN, Tianero MD, DiLuccia B, Ahern PP, Merriman J, Cortez VS, Caparon MG, Donia MS, Gilfillan S, Cella M, Gordon JI, Hsieh CS, Colonna M. Lactobacillus reuteri induces gut intraepithelial CD4(+)CD8αα(+) T cells. Science (New York, N.Y.). PMID 28775213 DOI: 10.1126/Science.Aah5825  0.244
2022 Urusova DV, Merriman JA, Gupta A, Chen L, Mathema B, Caparon MG, Khader SA. Rifampin resistance mutations in the rpoB gene of Enterococcus faecalis impact host macrophage cytokine production. Cytokine. 151: 155788. PMID 35030469 DOI: 10.1016/j.cyto.2021.155788  0.237
2022 Nye TM, Tükenmez H, Singh P, Flores-Mireles AL, Obernuefemann CLP, Pinkner JS, Sarkar S, Bonde M, Lindgren AEG, Dodson KW, Johansson J, Almqvist F, Caparon MG, Hultgren SJ. Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 119: e2210912119. PMID 36252016 DOI: 10.1073/pnas.2210912119  0.211
2024 Nye TM, Zou Z, Obernuefemann CLP, Pinkner JS, Lowry E, Kleinschmidt K, Bergeron K, Klim A, Dodson KW, Flores-Mireles AL, Walker JN, Wong DG, Desai A, Caparon MG, Hultgren SJ. Microbial co-occurrences on catheters from long-term catheterized patients. Nature Communications. 15: 61. PMID 38168042 DOI: 10.1038/s41467-023-44095-0  0.208
1997 Kaltwasser G, Diego J, Welby-Sellenriek PL, Ferrett R, Caparon M, Storch GA. Polymerase chain reaction for Streptococcus pyogenes used to evaluate an optical immunoassay for the detection of group A streptococci in children with pharyngitis. The Pediatric Infectious Disease Journal. 16: 748-53. PMID 9271035 DOI: 10.1097/00006454-199708000-00004  0.2
1988 Caparon M, Johnson W. Macrophage toxicity and complement sensitivity of virulent and avirulent strains of Legionella pneumophila. Reviews of Infectious Diseases. S377-81. PMID 3187322 DOI: 10.1093/cid/10.Supplement_2.S377  0.192
2023 Berna AZ, Merriman JA, Mellett L, Parchment DK, Caparon MG, Odom John AR. Volatile profiling distinguishes from other respiratory streptococcal species. Msphere. 8: e0019423. PMID 37791788 DOI: 10.1128/msphere.00194-23  0.175
2022 Urusova DV, Merriman JA, Gupta A, Chen L, Mathema B, Caparon MG, Khader SA. Corrigendum to "Rifampicin resistance mutations in the rpoB gene of Enterococcus faecalis affect the production of cytokines by host macrophages" Cytokine 151 (2022) 155788. Cytokine. 155845. PMID 35256256 DOI: 10.1016/j.cyto.2022.155845  0.169
1998 Okada N, Tatsuno L, Hanski E, Caparon M, Sasakawa C. A 1,3-beta-glucanosyltransferase isolated from the cell wall of Aspergillus fumigatus is a homologue of the yeast Bgl2p. Microbiology (Reading, England). 144: 3079-3086. PMID 9846753 DOI: 10.1099/00221287-144-11-3171  0.158
2019 Cho KH, Port GC, Caparon M. Genetics of Group A Streptococci. Microbiology Spectrum. 7. PMID 30825299 DOI: 10.1128/Microbiolspec.Gpp3-0056-2018  0.156
1989 Norgren M, Caparon MG, Scott JR. A method for allelic replacement that uses the conjugative transposon Tn916: Deletion of the emm6.1 allele in Streptococcus pyogenes JRS4 Infection and Immunity. 57: 3846-3850. PMID 2553613 DOI: 10.1128/Iai.57.12.3846-3850.1989  0.155
1997 Welply JK, Steininger CN, Caparon M, Michener ML, Howard SC, Pegg LE, Meyer DM, De Ciechi PA, Devine CS, Casperson GF. A peptide isolated by phage display binds to ICAM-1 and inhibits binding to LFA-1. Proteins. 26: 262-70. PMID 8953648 DOI: 10.1002/(SICI)1097-0134(199611)26:3<262::AID-PROT3>3.0.CO;2-G  0.153
1996 Lee JY, Caparon M. An oxygen-induced but protein F-independent fibronectin-binding pathway in Streptococcus pyogenes. Infection and Immunity. 64: 413-421. DOI: 10.1128/iai.64.2.413-421.1996  0.148
2022 Tükenmez H, Nye TM, Bonde M, Caparon MG, Almqvist F, Hultgren SJ, Johansson J. Complete Genome Sequence of the Uropathogenic Methicillin-Resistant Staphylococcus aureus Strain MRSA-1369. Microbiology Resource Announcements. 11: e0098122. PMID 36173194 DOI: 10.1128/mra.00981-22  0.13
1997 Wang B, Ruiz N, Pentland A, Caparon M. Keratinocyte proinflammatory responses to adherent and nonadherent group A streptococci. Infection and Immunity. 65: 2119-2126. DOI: 10.1128/iai.65.6.2119-2126.1997  0.069
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