James B. Konopka - Publications

Affiliations: 
Stony Brook University, Stony Brook, NY, United States 
Area:
Microbiology Biology

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Wang HX, Douglas LM, Veselá P, Rachel R, Malinsky J, Konopka JB. Eisosomes promote the ability of Sur7 to regulate plasma membrane organization in Candida albicans. Molecular Biology of the Cell. PMID 27009204 DOI: 10.1091/mbc.E16-01-0065  1
2016 Douglas LM, Konopka JB. Plasma membrane organization promotes virulence of the human fungal pathogen Candida albicans. Journal of Microbiology (Seoul, Korea). 54: 178-91. PMID 26920878 DOI: 10.1007/s12275-016-5621-y  1
2015 Li L, Naseem S, Sharma S, Konopka JB. Flavodoxin-Like Proteins Protect Candida albicans from Oxidative Stress and Promote Virulence. Plos Pathogens. 11: e1005147. PMID 26325183 DOI: 10.1371/journal.ppat.1005147  1
2015 Naseem S, Konopka JB. N-acetylglucosamine Regulates Virulence Properties in Microbial Pathogens. Plos Pathogens. 11: e1004947. PMID 26226264 DOI: 10.1371/journal.ppat.1004947  1
2015 Mor V, Rella A, Farnoud AM, Singh A, Munshi M, Bryan A, Naseem S, Konopka JB, Ojima I, Bullesbach E, Ashbaugh A, Linke MJ, Cushion M, Collins M, Ananthula HK, et al. Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids. Mbio. 6. PMID 26106079 DOI: 10.1128/mBio.00647-15  1
2015 Farnoud AM, Toledo AM, Konopka JB, Del Poeta M, London E. Raft-like membrane domains in pathogenic microorganisms. Current Topics in Membranes. 75: 233-68. PMID 26015285 DOI: 10.1016/bs.ctm.2015.03.005  1
2015 Guan G, Wang H, Liang W, Cao C, Tao L, Naseem S, Konopka JB, Wang Y, Huang G. The mitochondrial protein Mcu1 plays important roles in carbon source utilization, filamentation, and virulence in Candida albicans. Fungal Genetics and Biology : Fg & B. PMID 25626172 DOI: 10.1016/j.fgb.2015.01.006  1
2015 Naseem S, Araya E, Konopka JB. Hyphal growth in Candida albicans does not require induction of hyphal-specific gene expression. Molecular Biology of the Cell. 26: 1174-87. PMID 25609092 DOI: 10.1091/mbc.E14-08-1312  1
2015 Naseem S, Frank D, Konopka JB, Carpino N. Protection from Systemic Candida albicans infection by inactivation of the sts phosphatases Infection and Immunity. 83: 637-645. DOI: 10.1128/IAI.02789-14  1
2014 Douglas LM, Konopka JB. Fungal membrane organization: the eisosome concept. Annual Review of Microbiology. 68: 377-93. PMID 25002088 DOI: 10.1146/annurev-micro-091313-103507  1
2014 Okada H, Ohnuki S, Roncero C, Konopka JB, Ohya Y. Distinct roles of cell wall biogenesis in yeast morphogenesis as revealed by multivariate analysis of high-dimensional morphometric data. Molecular Biology of the Cell. 25: 222-33. PMID 24258022 DOI: 10.1091/mbc.E13-07-0396  1
2013 Douglas LM, Wang HX, Konopka JB. The MARVEL domain protein Nce102 regulates actin organization and invasive growth of Candida albicans. Mbio. 4: e00723-13. PMID 24281718 DOI: 10.1128/mBio.00723-13  1
2013 Gilmore SA, Naseem S, Konopka JB, Sil A. N-acetylglucosamine (GlcNAc) triggers a rapid, temperature-responsive morphogenetic program in thermally dimorphic fungi. Plos Genetics. 9: e1003799. PMID 24068964 DOI: 10.1371/journal.pgen.1003799  1
2013 Epp E, Nazarova E, Regan H, Douglas LM, Konopka JB, Vogel J, Whiteway M. Clathrin- and Arp2/3-independent endocytosis in the fungal pathogen Candida albicans. Mbio. 4: e00476-13. PMID 23982070 DOI: 10.1128/mBio.00476-13  1
2012 Li L, Zhang C, Konopka JB. A Candida albicans temperature-sensitive cdc12-6 mutant identifies roles for septins in selection of sites of germ tube formation and hyphal morphogenesis. Eukaryotic Cell. 11: 1210-8. PMID 22886998 DOI: 10.1128/EC.00216-12  1
2012 Naseem S, Parrino SM, Buenten DM, Konopka JB. Novel roles for GlcNAc in cell signaling. Communicative & Integrative Biology. 5: 156-9. PMID 22808320 DOI: 10.4161/cib.19034  1
2012 Douglas LM, Wang HX, Keppler-Ross S, Dean N, Konopka JB. Sur7 promotes plasma membrane organization and is needed for resistance to stressful conditions and to the invasive growth and virulence of Candida albicans. Mbio. 3. PMID 22202230 DOI: 10.1128/mBio.00254-11  1
2011 Douglas LM, Wang HX, Li L, Konopka JB. Membrane Compartment Occupied by Can1 (MCC) and Eisosome Subdomains of the Fungal Plasma Membrane. Membranes. 1: 394-411. PMID 22368779 DOI: 10.3390/membranes1040394  1
2011 Naseem S, Gunasekera A, Araya E, Konopka JB. N-acetylglucosamine (GlcNAc) induction of hyphal morphogenesis and transcriptional responses in Candida albicans are not dependent on its metabolism. The Journal of Biological Chemistry. 286: 28671-80. PMID 21700702 DOI: 10.1074/jbc.M111.249854  1
2011 Wang HX, Douglas LM, Aimanianda V, Latgé JP, Konopka JB. The Candida albicans Sur7 protein is needed for proper synthesis of the fibrillar component of the cell wall that confers strength. Eukaryotic Cell. 10: 72-80. PMID 21115741 DOI: 10.1128/EC.00167-10  1
2010 Dosil M, Konopka JB. Strategies for isolating constitutively active and dominant-negative pheromone receptor mutants in yeast. Methods in Enzymology. 485: 329-48. PMID 21050926 DOI: 10.1016/B978-0-12-381296-4.00019-1  1
2010 Keppler-Ross S, Douglas L, Konopka JB, Dean N. Recognition of yeast by murine macrophages requires mannan but not glucan. Eukaryotic Cell. 9: 1776-87. PMID 20833894 DOI: 10.1128/EC.00156-10  1
2010 Gunasekera A, Alvarez FJ, Douglas LM, Wang HX, Rosebrock AP, Konopka JB. Identification of GIG1, a GlcNAc-induced gene in Candida albicans needed for normal sensitivity to the chitin synthase inhibitor nikkomycin Z. Eukaryotic Cell. 9: 1476-83. PMID 20675577 DOI: 10.1128/EC.00178-10  1
2010 Zhang C, Konopka JB. A photostable green fluorescent protein variant for analysis of protein localization in Candida albicans. Eukaryotic Cell. 9: 224-6. PMID 19915075 DOI: 10.1128/EC.00327-09  1
2009 Alvarez FJ, Douglas LM, Konopka JB. The Sur7 protein resides in punctate membrane subdomains and mediates spatial regulation of cell wall synthesis in Candida albicans. Communicative & Integrative Biology. 2: 76-7. PMID 19704893  1
2009 Douglas LM, Martin SW, Konopka JB. BAR domain proteins Rvs161 and Rvs167 contribute to Candida albicans endocytosis, morphogenesis, and virulence. Infection and Immunity. 77: 4150-60. PMID 19596778 DOI: 10.1128/IAI.00683-09  1
2009 Wang HX, Konopka JB. Identification of amino acids at two dimer interface regions of the alpha-factor receptor (Ste2). Biochemistry. 48: 7132-9. PMID 19588927 DOI: 10.1021/bi900424h  1
2008 Alvarez FJ, Douglas LM, Rosebrock A, Konopka JB. The Sur7 protein regulates plasma membrane organization and prevents intracellular cell wall growth in Candida albicans. Molecular Biology of the Cell. 19: 5214-25. PMID 18799621 DOI: 10.1091/mbc.E08-05-0479  1
2008 Bharucha JP, Larson JR, Konopka JB, Tatchell K. Saccharomyces cerevisiae Afr1 protein is a protein phosphatase 1/Glc7-targeting subunit that regulates the septin cytoskeleton during mating. Eukaryotic Cell. 7: 1246-55. PMID 18552279 DOI: 10.1128/EC.00024-08  1
2008 Gladue DP, Konopka JB. Scanning mutagenesis of regions in the Galpha protein Gpa1 that are predicted to interact with yeast mating pheromone receptors. Fems Yeast Research. 8: 71-80. PMID 17892473 DOI: 10.1111/j.1567-1364.2007.00311.x  1
2007 Alvarez FJ, Douglas LM, Konopka JB. Sterol-rich plasma membrane domains in fungi. Eukaryotic Cell. 6: 755-63. PMID 17369440 DOI: 10.1128/EC.00008-07  1
2007 Eifler N, Duckely M, Sumanovski LT, Egan TM, Oksche A, Konopka JB, Lüthi A, Engel A, Werten PJ. Functional expression of mammalian receptors and membrane channels in different cells. Journal of Structural Biology. 159: 179-93. PMID 17368047 DOI: 10.1016/j.jsb.2007.01.014  1
2007 Alvarez FJ, Konopka JB. Identification of an N-acetylglucosamine transporter that mediates hyphal induction in Candida albicans. Molecular Biology of the Cell. 18: 965-75. PMID 17192409 DOI: 10.1091/mbc.E06-10-0931  1
2006 Choi Y, Konopka JB. Accessibility of cysteine residues substituted into the cytoplasmic regions of the alpha-factor receptor identifies the intracellular residues that are available for G protein interaction. Biochemistry. 45: 15310-7. PMID 17176053 DOI: 10.1021/bi0614939  1
2006 Ballon DR, Flanary PL, Gladue DP, Konopka JB, Dohlman HG, Thorner J. DEP-domain-mediated regulation of GPCR signaling responses. Cell. 126: 1079-93. PMID 16990133 DOI: 10.1016/j.cell.2006.07.030  1
2005 Douglas LM, Alvarez FJ, McCreary C, Konopka JB. Septin function in yeast model systems and pathogenic fungi. Eukaryotic Cell. 4: 1503-12. PMID 16151244 DOI: 10.1128/EC.4.9.1503-1512.2005  1
2005 Martin SW, Douglas LM, Konopka JB. Cell cycle dynamics and quorum sensing in Candida albicans chlamydospores are distinct from budding and hyphal growth. Eukaryotic Cell. 4: 1191-202. PMID 16002645 DOI: 10.1128/EC.4.7.1191-1202.2005  1
2005 Eilers M, Hornak V, Smith SO, Konopka JB. Comparison of class A and D G protein-coupled receptors: common features in structure and activation. Biochemistry. 44: 8959-75. PMID 15966721 DOI: 10.1021/bi047316u  1
2005 Yin D, Gavi S, Shumay E, Duell K, Konopka JB, Malbon CC, Wang HY. Successful expression of a functional yeast G-protein-coupled receptor (Ste2) in mammalian cells. Biochemical and Biophysical Research Communications. 329: 281-7. PMID 15721304 DOI: 10.1016/j.bbrc.2005.01.130  1
2005 Lin JC, Duell K, Saracino M, Konopka JB. Identification of residues that contribute to receptor activation through the analysis of compensatory mutations in the G protein-coupled alpha-factor receptor. Biochemistry. 44: 1278-87. PMID 15667221 DOI: 10.1021/bi048050u  1
2004 Martin SW, Konopka JB. SUMO modification of septin-interacting proteins in Candida albicans. The Journal of Biological Chemistry. 279: 40861-7. PMID 15277521 DOI: 10.1074/jbc.M406422200  1
2004 Martin SW, Konopka JB. Lipid raft polarization contributes to hyphal growth in Candida albicans. Eukaryotic Cell. 3: 675-84. PMID 15189988 DOI: 10.1128/EC.3.3.675-684.2004  1
2004 Lin JC, Duell K, Konopka JB. A microdomain formed by the extracellular ends of the transmembrane domains promotes activation of the G protein-coupled alpha-factor receptor. Molecular and Cellular Biology. 24: 2041-51. PMID 14966283 DOI: 10.1128/MCB.24.5.2041-2051.2004  1
2003 Warenda AJ, Kauffman S, Sherrill TP, Becker JM, Konopka JB. Candida albicans septin mutants are defective for invasive growth and virulence. Infection and Immunity. 71: 4045-51. PMID 12819094 DOI: 10.1128/IAI.71.7.4045-4051.2003  1
2003 Lin JC, Parrish W, Eilers M, Smith SO, Konopka JB. Aromatic residues at the extracellular ends of transmembrane domains 5 and 6 promote ligand activation of the G protein-coupled alpha-factor receptor. Biochemistry. 42: 293-301. PMID 12525156 DOI: 10.1021/bi026766o  1
2002 Osman MA, Konopka JB, Cerione RA. Iqg1p links spatial and secretion landmarks to polarity and cytokinesis. The Journal of Cell Biology. 159: 601-11. PMID 12446742 DOI: 10.1083/jcb.200205084  1
2002 Warenda AJ, Konopka JB. Septin function in Candida albicans morphogenesis. Molecular Biology of the Cell. 13: 2732-46. PMID 12181342 DOI: 10.1091/mbc.E02-01-0013  1
2002 Parrish W, Eilers M, Ying W, Konopka JB. The cytoplasmic end of transmembrane domain 3 regulates the activity of the Saccharomyces cerevisiae G-protein-coupled alpha-factor receptor. Genetics. 160: 429-43. PMID 11861550  1
2002 Mentesana PE, Dosil M, Konopka JB. Functional assays for mammalian G-protein-coupled receptors in yeast. Methods in Enzymology. 344: 92-111. PMID 11771426 DOI: 10.1016/S0076-6879(02)44708-8  1
2001 Mentesana PE, Konopka JB. Mutational analysis of the role of N-glycosylation in α-factor receptor function Biochemistry. 40: 9685-9694. PMID 11583169 DOI: 10.1021/bi0108507  1
2000 Crosby JA, Konopka JB, Fields S. Constitutive activation of the Saccharomyces cerevisiae transcriptional regulator ste12p by mutations at the amino-terminus Yeast. 16: 1365-1375. PMID 11054817 DOI: 10.1002/1097-0061(200011)16:15<1365::AID-YEA630>3.0.CO;2-S  1
2000 Dosil M, Schandel KA, Gupta E, Jenness DD, Konopka JB. The C terminus of the Saccharomyces cerevisiae α-factor receptor contributes to the formation of preactivation complexes with its cognate G protein Molecular and Cellular Biology. 20: 5321-5329. PMID 10866688 DOI: 10.1128/MCB.20.14.5321-5329.2000  1
2000 Dube P, DeCostanzo A, Konopka JB. Interaction between transmembrane domains five and six of the alpha -factor receptor. The Journal of Biological Chemistry. 275: 26492-9. PMID 10846179 DOI: 10.1074/jbc.M002767200  1
2000 DeMattei CR, Davis CP, Konopka JB. Point mutations identify a conserved region of the saccharomyces cerevisiae AFR1 gene that is essential for both the pheromone signaling and morphogenesis functions. Genetics. 155: 43-55. PMID 10790383  1
1999 Giot L, Demattei C, Konopka JB. Combining mutations in the incoming and outgoing pheromone signal pathways causes a synergistic mating defect in Saccharomyces cerevisiae Yeast. 15: 765-780. PMID 10398345 DOI: 10.1002/(SICI)1097-0061(19990630)15:9<765::AID-YEA418>3.0.CO;2-4  1
1998 Dube P, Konopka JB. Identification of a polar region in transmembrane domain 6 that regulates the function of the G protein-coupled α-factor receptor Molecular and Cellular Biology. 18: 7205-7215. PMID 9819407  1
1998 Dosil M, Giot L, Davis C, Konopka JB. Dominant-negative mutations in the G-protein-coupled α-factor receptor map to the extracellular ends of the transmembrane segments Molecular and Cellular Biology. 18: 5981-5991. PMID 9742115  1
1998 Davis C, Dube P, Konopka JB. Afr1p regulates the Saccharomyces cerevisiae α-factor receptor by a mechanism that is distinct from receptor phosphorylation and endocytosis Genetics. 148: 625-635. PMID 9504911  1
1997 Le S, Davis C, Konopka JB, Sternglanz R. Two new S-phase-specific genes from Saccharomyces cerevisiae Yeast. 13: 1029-1042. PMID 9290207 DOI: 10.1002/(SICI)1097-0061(19970915)13:11<1029::AID-YEA160>3.0.CO;2-1  1
1997 Giot L, Konopka JB. Functional analysis of the interaction between Afr1p and the Cdc12p septin, two proteins involved in pheromone-induced morphogenesis Molecular Biology of the Cell. 8: 987-998. PMID 9201710  1
1996 Konopka JB, Margarit SM, Dube P. Mutation of Pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled α-factor receptor Proceedings of the National Academy of Sciences of the United States of America. 93: 6764-6769. PMID 8692892 DOI: 10.1073/pnas.93.13.6764  1
1996 Chen Q, Konopka JB. Regulation of the G-protein-coupled α-factor pheromone receptor by phosphorylation Molecular and Cellular Biology. 16: 247-257. PMID 8524302  1
1995 Konopka JB, Demattei C, Davis C. AFR1 promotes polarized apical morphogenesis in Saccharomyces cerevisiae Molecular and Cellular Biology. 15: 723-730. PMID 7823940  1
1993 Konopka JB. AFR1 acts in conjunction with the α-factor receptor to promote morphogenesis and adaptation Molecular and Cellular Biology. 13: 6876-6888. PMID 8413281  1
1992 Konopka JB, Fields S. The pheromone signal pathway in Saccharomyces cerevisiae Antonie Van Leeuwenhoek. 62: 95-108. PMID 1444339 DOI: 10.1007/BF00584465  1
1991 Jackson CL, Konopka JB, Hartwell LH. S. cerevisiae alpha pheromone receptors activate a novel signal transduction pathway for mating partner discrimination. Cell. 67: 389-402. PMID 1655282 DOI: 10.1016/0092-8674(91)90190-A  1
1991 Konopka JB, Jenness DD. Genetic fine-structural analysis of the Saccharomyces cerevisiae alpha-pheromone receptor Cell Regulation. 2: 439-452. PMID 1653030  1
1991 Konopka JB, Jenness DD. Genetic fine-structural analysis of the Saccharomyces cerevisiae α-pheromone receptor Molecular Biology of the Cell. 2: 439-452.  1
1988 Cross F, Hartwell LH, Jackson C, Konopka JB. Conjugation in Saccharomyces cerevisiae. Annual Review of Cell Biology. 4: 429-57. PMID 2848554 DOI: 10.1146/annurev.cb.04.110188.002241  1
1988 Konopka JB, Jenness DD, Hartwell LH. The C-terminus of the S. cerevisiae alpha-pheromone receptor mediates an adaptive response to pheromone. Cell. 54: 609-20. PMID 2842059 DOI: 10.1016/S0092-8674(88)80005-9  1
1986 Kozbor D, Giallongo A, Sierzega ME, Konopka JB, Witte ON, Showe LC, Croce CM. Expression of a translocated c-abl gene in hybrids of mouse fibroblasts and chronic myelogenous leukaemia cells. Nature. 319: 331-3. PMID 3455750 DOI: 10.1038/319331a0  1
1986 Konopka JB, Clark S, McLaughlin J, Nitta M, Kato Y, Strife A, Clarkson B, Witte ON. Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients Proceedings of the National Academy of Sciences of the United States of America. 83: 4049-4052. PMID 3012546  1
1986 Schiff-Maker L, Burns MC, Konopka JB, Clark S, Witte ON, Rosenberg N. Monoclonal antibodies specific for v-abl- and c-abl-encoded molecules Journal of Virology. 57: 1182-1186. PMID 3005619  1
1985 Davis RL, Konopka JB, Witte ON. Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties Molecular and Cellular Biology. 5: 204-213. PMID 4039028  1
1985 Konopka JB, Witte ON. Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products Molecular and Cellular Biology. 5: 3116-3123. PMID 3879812  1
1985 Konopka JB, Watanabe SM, Singer JW, Collins SJ, Witte ON. Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration Proceedings of the National Academy of Sciences of the United States of America. 82: 1810-1814. PMID 3856862 DOI: 10.1073/pnas.82.6.1810  1
1985 Konopka JB, Witte ON. Activation of the abl oncogene in murine and human leukemias Bba - Reviews On Cancer. 823: 1-17. PMID 2996602 DOI: 10.1016/0304-419X(85)90012-5  1
1984 Konopka JB, Davis RL, Watanabe SM, Ponticelli AS, Schiff-Maker L, Rosenberg N, Witte ON. Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity Journal of Virology. 51: 223-232. PMID 6610061  1
1984 Konopka JB, Watanabe SM, Witte ON. An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity Cell. 37: 1035-1042. PMID 6204766 DOI: 10.1016/0092-8674(84)90438-0  1
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