Year |
Citation |
Score |
2024 |
Vaughn H, Major H, Kadera E, Keck K, Dunham T, Qian Q, Brown B, Scott A, Bellizzi AM, Braun T, Breheny P, Quelle DE, Howe JR, Darbro B. Functional Copy-Number Alterations as Diagnostic and Prognostic Biomarkers in Neuroendocrine Tumors. International Journal of Molecular Sciences. 25. PMID 39062773 DOI: 10.3390/ijms25147532 |
0.334 |
|
2023 |
Tow DH, Tran CG, Borbon LC, Ridder M, Li G, Kaemmer CA, Abusada E, Mahalingam AH, Sadanandam A, Chandrasekaran C, Dillon J, Spitz DR, Quelle DE, Chan CHF, Bellizzi A, et al. Inhibition of serotonin biosynthesis in neuroendocrine neoplasm suppresses tumor growth . Biorxiv : the Preprint Server For Biology. PMID 37066322 DOI: 10.1101/2023.04.07.536013 |
0.388 |
|
2022 |
Kohlmeyer JL, Kaemmer CA, Lingo JJ, Voigt E, Leidinger MR, McGivney GR, Scherer A, Koppenhafer SL, Gordon DJ, Breheny P, Meyerholz DK, Tanas MR, Dodd RD, Quelle DE. Oncogenic RABL6A promotes NF1-associated MPNST progression in vivo. Neuro-Oncology Advances. 4: vdac047. PMID 35571990 DOI: 10.1093/noajnl/vdac047 |
0.323 |
|
2021 |
Maharjan CK, Umesalma S, Kaemmer CA, Muniz VP, Bauchle C, Mott SL, Zamba KD, Breheny P, Leidinger MR, Darbro BW, Stephens SB, Meyerholz DK, Quelle DE. RABL6A Promotes Pancreatic Neuroendocrine Tumor Angiogenesis and Progression In Vivo. Biomedicines. 9. PMID 34199469 DOI: 10.3390/biomedicines9060633 |
0.792 |
|
2021 |
Kohlmeyer JL, Kaemmer CA, Umesalma S, Gourronc FA, Klingelhutz AJ, Quelle DE. RABL6A Regulates Schwann Cell Senescence in an RB1-Dependent Manner. International Journal of Molecular Sciences. 22. PMID 34065204 DOI: 10.3390/ijms22105367 |
0.356 |
|
2021 |
Kaemmer CA, Umesalma S, Maharjan CK, Moose DL, Narla G, Mott SL, Zamba GKD, Breheny P, Darbro BW, Bellizzi AM, Henry MD, Quelle DE. Development and comparison of novel bioluminescent mouse models of pancreatic neuroendocrine neoplasm metastasis. Scientific Reports. 11: 10252. PMID 33986468 DOI: 10.1038/s41598-021-89866-1 |
0.335 |
|
2021 |
Desai C, Thomason J, Kohlmeyer JL, Reisetter AC, Ahirwar P, Jahanseir K, Leidinger M, Ofori-Amanfo G, Fritchie K, Velu SE, Breheny P, Quelle DE, Tanas MR. Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas. Oncotarget. 12: 740-755. PMID 33889298 DOI: 10.18632/oncotarget.27928 |
0.358 |
|
2021 |
Kohlmeyer JL, Gordon DJ, Tanas MR, Dodd RD, Monga V, Darbro BW, Quelle DE. Combination therapies for MPNSTs targeting RABL6A-RB1 signaling. Oncotarget. 12: 10-14. PMID 33456709 DOI: 10.18632/oncotarget.27862 |
0.31 |
|
2020 |
Kohlmeyer JL, Gordon DJ, Tanas MR, Monga V, Dodd RD, Quelle DE. CDKs in Sarcoma: Mediators of Disease and Emerging Therapeutic Targets. International Journal of Molecular Sciences. 21. PMID 32344731 DOI: 10.3390/Ijms21083018 |
0.472 |
|
2020 |
Kohlmeyer JL, Kaemmer CA, Pulliam C, Maharjan CK, Moreno Samayoa A, Major HJ, Cornick KE, Knepper-Adrian V, Khanna R, Sieren JC, Leidinger M, Meyerholz DK, Zamba KD, Weimer J, Dodd RD, ... ... Quelle DE, et al. RABL6A is an essential driver of MPNSTs that negatively regulates the RB1 pathway and sensitizes tumor cells to CDK4/6 inhibitors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32086342 DOI: 10.1158/1078-0432.Ccr-19-2706 |
0.479 |
|
2020 |
Scott AT, Weitz M, Breheny PJ, Ear PH, Darbro B, Brown BJ, Braun TA, Li G, Umesalma S, Kaemmer CA, Maharjan CK, Quelle DE, Bellizzi AM, Chandrasekharan C, Dillon JS, et al. Gene Expression Signatures Identify Novel Therapeutics for Metastatic Pancreatic Neuroendocrine Tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31937620 DOI: 10.1158/1078-0432.Ccr-19-2884 |
0.397 |
|
2020 |
Chau J, Dhungana N, Kohlmeyer J, Petronek M, Quelle D, Sato M, Darbro B, Jones K, Monga V. Genome-wide methylation analysis in long-term survivors of glioblastoma (GBM). Journal of Clinical Oncology. 38: 2552-2552. DOI: 10.1200/Jco.2020.38.15_Suppl.2552 |
0.37 |
|
2019 |
Umesalma S, Kaemmer CA, Kohlmeyer JL, Letney BL, Schab AM, Reilly JA, Sheehy RM, Hagen J, Tiwari N, Zhan F, Leidinger MR, O'Dorisio TM, Dillon JS, Merrill RA, Meyerholz DK, ... ... Quelle DE, et al. RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth. The Journal of Clinical Investigation. PMID 30721156 DOI: 10.1172/Jci123049 |
0.497 |
|
2018 |
Meng X, Yang S, Li Y, Li Y, Devor EJ, Bi J, Wang X, Umesalma S, Quelle DE, Thiel WH, Thiel KW, Leslie KK. Combination of Proteasome and Histone Deacetylase Inhibitors Overcomes the Impact of Gain-of-Function p53 Mutations. Disease Markers. 2018: 3810108. PMID 30647797 DOI: 10.1155/2018/3810108 |
0.436 |
|
2018 |
White KA, Swier VJ, Cain JT, Kohlmeyer JL, Meyerholz DK, Tanas MR, Uthoff J, Hammond E, Li H, Rohret FA, Goeken A, Chan CH, Leidinger MR, Umesalma S, Wallace MR, ... ... Quelle DE, et al. A porcine model of neurofibromatosis type 1 that mimics the human disease. Jci Insight. 3. PMID 29925695 DOI: 10.1172/Jci.Insight.120402 |
0.364 |
|
2017 |
Meyerholz DK, Ofori-Amanfo GK, Leidinger MR, Goeken JA, Khanna R, Sieren JC, Darbro BW, Quelle DE, Weimer JM. Immunohistochemical Markers for Prospective Studies in Neurofibromatosis-1 Porcine Models. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 22155417729357. PMID 28846462 DOI: 10.1369/0022155417729357 |
0.381 |
|
2017 |
Pardo M, Yu L, Shen S, Tate P, Bode D, Letney BL, Quelle DE, Skarnes W, Choudhary JS. Myst2/Kat7 histone acetyltransferase interaction proteomics reveals tumour-suppressor Niam as a novel binding partner in embryonic stem cells. Scientific Reports. 7: 8157. PMID 28811661 DOI: 10.1038/S41598-017-08456-2 |
0.387 |
|
2017 |
Salma SAU, Hagen J, Reilly J, Sheehy R, Tiwari N, Nteeba J, Sherman SK, O'Dorisio TM, Howe JR, Bellizzi AM, Darbro BW, Quelle DE. Abstract 1368: RABL6A, a novel critical regulator of Akt-mTOR signaling in pancreatic neuroendocrine tumor cells Cancer Research. 77: 1368-1368. DOI: 10.1158/1538-7445.Am2017-1368 |
0.446 |
|
2014 |
Sieren JC, Quelle D, Meyerholz DK, Rogers CS. Porcine cancer models for translational oncology. Molecular & Cellular Oncology. 1: e969626. PMID 27308376 DOI: 10.4161/23723548.2014.969626 |
0.31 |
|
2014 |
Reed SM, Quelle DE. p53 Acetylation: Regulation and Consequences. Cancers. 7: 30-69. PMID 25545885 DOI: 10.3390/Cancers7010030 |
0.549 |
|
2014 |
Reed SM, Hagen J, Muniz VP, Rosean TR, Borcherding N, Sciegienka S, Goeken JA, Naumann PW, Zhang W, Tompkins VS, Janz S, Meyerholz DK, Quelle DE. NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas. Plos One. 9: e112126. PMID 25393878 DOI: 10.1371/Journal.Pone.0112126 |
0.769 |
|
2014 |
Hagen J, Muniz VP, Falls KC, Reed SM, Taghiyev AF, Quelle FW, Gourronc FA, Klingelhutz AJ, Major HJ, Askeland RW, Sherman SK, O'Dorisio TM, Bellizzi AM, Howe JR, Darbro BW, ... Quelle DE, et al. RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner. Cancer Research. 74: 6661-70. PMID 25273089 DOI: 10.1158/0008-5472.Can-13-3742 |
0.819 |
|
2014 |
Sieren JC, Meyerholz DK, Wang XJ, Davis BT, Newell JD, Hammond E, Rohret JA, Rohret FA, Struzynski JT, Goeken JA, Naumann PW, Leidinger MR, Taghiyev A, Van Rheeden R, Hagen J, ... ... Quelle DE, et al. Development and translational imaging of a TP53 porcine tumorigenesis model. The Journal of Clinical Investigation. 124: 4052-66. PMID 25105366 DOI: 10.1172/Jci75447 |
0.44 |
|
2014 |
Reed SM, Quelle FW, Quelle DE. ARF sees Pdgfrβ through the miR. Cell Cycle (Georgetown, Tex.). 13: 1520-1. PMID 24755551 DOI: 10.4161/Cc.28900 |
0.404 |
|
2014 |
Reed SM, Hagen J, Tompkins VS, Thies K, Quelle FW, Quelle DE. Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53. Cell Cycle (Georgetown, Tex.). 13: 1288-98. PMID 24621507 DOI: 10.4161/Cc.28202 |
0.774 |
|
2014 |
Huang J, Stewart A, Maity B, Hagen J, Fagan RL, Yang J, Quelle DE, Brenner C, Fisher RA. RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 degradation and promoting apoptosis. Oncogene. 33: 3604-11. PMID 23995786 DOI: 10.1038/Onc.2013.324 |
0.384 |
|
2014 |
Sieren JC, Wang X, Davis B, Newell JD, Hammond E, Rohret J, Rohret F, Struzynski J, Goeken A, Naumann P, Leidinger M, Hagen J, Rheeden RV, Darbro BW, Quelle DE, et al. Abstract LB-162: Translational imaging of tumorigenesis in aTP53porcine cancer model Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-162 |
0.426 |
|
2013 |
Zhang X, Hagen J, Muniz VP, Smith T, Coombs GS, Eischen CM, Mackie DI, Roman DL, Van Rheeden R, Darbro B, Tompkins VS, Quelle DE. RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts. Plos One. 8: e80228. PMID 24282525 DOI: 10.1371/Journal.Pone.0080228 |
0.798 |
|
2013 |
Muniz VP, Askeland RW, Zhang X, Reed SM, Tompkins VS, Hagen J, McDowell BD, Button A, Smith BJ, Weydert JA, Mezhir JJ, Quelle DE. RABL6A Promotes Oxaliplatin Resistance in Tumor Cells and Is a New Marker of Survival for Resected Pancreatic Ductal Adenocarcinoma Patients. Genes & Cancer. 4: 273-84. PMID 24167655 DOI: 10.1177/1947601913501074 |
0.761 |
|
2012 |
Muniz VP, Zhang X, Reed SM, Tompkins VS, Smith T, Hagen JK, Fitzgerald M, Button A, Smith B, Zamba KD, Domann FE, Mezhir JJ, Weydert J, Askeland RA, Quelle DE. Abstract 712: Parf-1A (Partner of ARF isoform 1A) promotes oxaliplatin resistance and is a new prognostic marker of survival in pancreatic ductal adenocarcinoma Cancer Research. 72: 712-712. DOI: 10.1158/1538-7445.Am2012-712 |
0.767 |
|
2012 |
Reed S, Tompkins V, Hagen J, Thies K, Cryderman D, Wallrath L, Quelle D. Abstract 215: Mechanisms of p53 activation by NIAM, nuclear interactor of ARF and MDM2 Cancer Research. 72: 215-215. DOI: 10.1158/1538-7445.Am2012-215 |
0.76 |
|
2011 |
Muniz VP, Barnes JM, Paliwal S, Zhang X, Tang X, Chen S, Zamba KD, Cullen JJ, Meyerholz DK, Meyers S, Davis JN, Grossman SR, Henry MD, Quelle DE. The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis. Molecular Cancer Research : McR. 9: 867-77. PMID 21636682 DOI: 10.1158/1541-7786.Mcr-10-0475 |
0.804 |
|
2009 |
di Tommaso A, Hagen J, Tompkins V, Muniz V, Dudakovic A, Kitzis A, Ladeveze V, Quelle DE. Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activities. Experimental Cell Research. 315: 1326-35. PMID 19331830 DOI: 10.1016/J.Yexcr.2009.01.010 |
0.794 |
|
2008 |
Hagen J, Tompkins V, Dudakovic A, Weydert JA, Quelle DE. Generation and characterization of monoclonal antibodies to NIAM: a nuclear interactor of ARF and Mdm2. Hybridoma (2005). 27: 159-66. PMID 18582208 DOI: 10.1089/Hyb.2007.0533 |
0.735 |
|
2007 |
Groskreutz DJ, Monick MM, Yarovinsky TO, Powers LS, Quelle DE, Varga SM, Look DC, Hunninghake GW. Respiratory syncytial virus decreases p53 protein to prolong survival of airway epithelial cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 2741-7. PMID 17709487 DOI: 10.4049/Jimmunol.179.5.2741 |
0.507 |
|
2007 |
Tompkins VS, Hagen J, Frazier AA, Lushnikova T, Fitzgerald MP, di Tommaso A, Ladeveze V, Domann FE, Eischen CM, Quelle DE. A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability. The Journal of Biological Chemistry. 282: 1322-33. PMID 17110379 DOI: 10.1074/Jbc.M609612200 |
0.805 |
|
2006 |
Tompkins V, Hagen J, Zediak VP, Quelle DE. Identification of novel ARF binding proteins by two-hybrid screening. Cell Cycle (Georgetown, Tex.). 5: 641-6. PMID 16582619 DOI: 10.4161/Cc.5.6.2560 |
0.745 |
|
2006 |
Miller SJ, Rangwala F, Williams J, Ackerman P, Kong S, Jegga AG, Kaiser S, Aronow BJ, Frahm S, Kluwe L, Mautner V, Upadhyaya M, Muir D, Wallace M, Hagen J, ... Quelle DE, et al. Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues. Cancer Research. 66: 2584-91. PMID 16510576 DOI: 10.1158/0008-5472.Can-05-3330 |
0.432 |
|
2005 |
Datta A, Sen J, Hagen J, Korgaonkar CK, Caffrey M, Quelle DE, Hughes DE, Ackerson TJ, Costa RH, Raychaudhuri P. ARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF. Molecular and Cellular Biology. 25: 8024-36. PMID 16135794 DOI: 10.1128/Mcb.25.18.8024-8036.2005 |
0.806 |
|
2005 |
Korgaonkar C, Hagen J, Tompkins V, Frazier AA, Allamargot C, Quelle FW, Quelle DE. Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function. Molecular and Cellular Biology. 25: 1258-71. PMID 15684379 DOI: 10.1128/Mcb.25.4.1258-1271.2005 |
0.792 |
|
2003 |
Zhao L, Samuels T, Winckler S, Korgaonkar C, Tompkins V, Horne MC, Quelle DE. Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways. Molecular Cancer Research : McR. 1: 195-206. PMID 12556559 |
0.797 |
|
2002 |
Linggi B, Müller-Tidow C, van de Locht L, Hu M, Nip J, Serve H, Berdel WE, van der Reijden B, Quelle DE, Rowley JD, Cleveland J, Jansen JH, Pandolfi PP, Hiebert SW. The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia. Nature Medicine. 8: 743-50. PMID 12091906 DOI: 10.1038/Nm726 |
0.517 |
|
2002 |
Korgaonkar C, Zhao L, Modestou M, Quelle DE. ARF function does not require p53 stabilization or Mdm2 relocalization. Molecular and Cellular Biology. 22: 196-206. PMID 11739734 DOI: 10.1128/Mcb.22.1.196-206.2002 |
0.815 |
|
2001 |
Eapen AK, Henry MK, Quelle DE, Quelle FW. DNA damage-induced G1 arrest in hematopoietic cells is overridden following phosphatidylinositol 3-kinase-dependent activation of cyclin-dependent kinase 2 Molecular and Cellular Biology. 21: 6113-6121. PMID 11509654 DOI: 10.1128/Mcb.21.18.6113-6121.2001 |
0.393 |
|
2001 |
Modestou M, Puig-Antich V, Korgaonkar C, Eapen A, Quelle DE. The alternative reading frame tumor suppressor inhibits growth through p21-dependent and p21-independent pathways Cancer Research. 61: 3145-3150. PMID 11306500 |
0.504 |
|
1997 |
Kamijo T, Zindy F, Roussel MF, Quelle DE, Downing JR, Ashmun RA, Grosveld G, Sherr CJ. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell. 91: 649-59. PMID 9393858 DOI: 10.1016/S0092-8674(00)80452-3 |
0.57 |
|
1997 |
Zindy F, Quelle DE, Roussel MF, Sherr CJ. Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging. Oncogene. 15: 203-11. PMID 9244355 DOI: 10.1038/Sj.Onc.1201178 |
0.438 |
|
1997 |
Quelle DE, Cheng M, Ashmun RA, Sherr CJ. Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16(INK4a) but not by the alternative reading frame protein p19(ARF) Proceedings of the National Academy of Sciences of the United States of America. 94: 669-673. PMID 9012842 DOI: 10.1073/Pnas.94.2.669 |
0.404 |
|
1995 |
Quelle DE, Ashmun RA, Hannon GJ, Rehberger PA, Trono D, Richter KH, Walker C, Beach D, Sherr CJ, Serrano M. Cloning and characterization of murine p16INK4a and p15INK4b genes Oncogene. 11: 635-645. PMID 7651726 |
0.31 |
|
1995 |
Linardopoulos S, Street AJ, Quelle DE, Parry D, Peters G, Sherr CJ, Balmain A. Deletion and altered regulation p16INK4a and p15INK4b in undifferentiated mouse skin tumors Cancer Research. 55: 5168-5172. PMID 7585567 |
0.346 |
|
1994 |
Matsushime H, Quelle DE, Shurtleff SA, Shibuya M, Sherr CJ, Kato JY. D-type cyclin-dependent kinase activity in mammalian cells Molecular and Cellular Biology. 14: 2066-2076. PMID 8114738 DOI: 10.1128/Mcb.14.3.2066 |
0.329 |
|
1993 |
Quelle DE, Ashmun RA, Shurtleff SA, Kato JY, Bar-Sagi D, Roussel MF, Sherr CJ. Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts Genes and Development. 7: 1559-1571. PMID 8339933 DOI: 10.1101/Gad.7.8.1559 |
0.343 |
|
1992 |
Quelle DE, Quelle FW, Wojchowski DM. Mutations in the WSAWSE and Cytosolic Domains of the Erythropoietin Receptor Affect Signal Transduction and Ligand Binding and Internalization Molecular and Cellular Biology. 12: 4553-4561. PMID 1406645 DOI: 10.1128/Mcb.12.10.4553 |
0.307 |
|
1992 |
Quelle DE, Lynch KJ, Burkert-Smith RE, Weiss S, Whitford W, Wojchowski DM. Phosphorylatable and epitope-tagged human erythropoietins: Utility and purification of native baculovirus-derived forms Protein Expression and Purification. 3: 461-469. PMID 1283094 DOI: 10.1016/1046-5928(92)90063-3 |
0.349 |
|
1991 |
Quelle DE, Wojchowski DM. Localized cytosolic domains of the erythropoietin receptor regulate growth signaling and down-modulate responsiveness to granulocyte-macrophage colony-stimulating factor Proceedings of the National Academy of Sciences of the United States of America. 88: 4801-4805. PMID 1711211 DOI: 10.1073/Pnas.88.11.4801 |
0.361 |
|
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