Nidhi Sahni, Ph.D. - Publications

2010 Biology University of Iowa, Iowa City, IA 
Microbiology Biology, Cell Biology, Molecular Biology

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Li Y, McGrail DJ, Xu J, Li J, Liu NN, Sun M, Lin R, Pancsa R, Zhang J, Lee JS, Wang H, Mills GB, Li X, Yi S, Sahni N. MERIT: Systematic analysis and characterization of Mutational Effect on RNA Interactome Topology. Hepatology (Baltimore, Md.). PMID 30153342 DOI: 10.1002/hep.30242  0.88
2018 Li Y, McGrail DJ, Xu J, Mills GB, Sahni N, Yi S. Gene Regulatory Network Perturbation by Genetic and Epigenetic Variation. Trends in Biochemical Sciences. PMID 29941230 DOI: 10.1016/j.tibs.2018.05.002  0.88
2018 Li Y, McGrail DJ, Latysheva N, Yi S, Babu MM, Sahni N. Pathway perturbations in signaling networks: Linking genotype to phenotype. Seminars in Cell & Developmental Biology. PMID 29738884 DOI: 10.1016/j.semcdb.2018.05.001  0.88
2018 McGrail DJ, Federico L, Li Y, Dai H, Lu Y, Mills GB, Yi S, Lin SY, Sahni N. Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers. Nature Communications. 9: 1317. PMID 29615613 DOI: 10.1038/s41467-018-03730-x  0.88
2018 Ng PK, Li J, Jeong KJ, Shao S, Chen H, Tsang YH, Sengupta S, Wang Z, Bhavana VH, Tran R, Soewito S, Minussi DC, Moreno D, Kong K, Dogruluk T, ... ... Sahni N, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 33: 450-462.e10. PMID 29533785 DOI: 10.1016/j.ccell.2018.01.021  0.88
2018 Li Y, Li L, Wang Z, Pan T, Sahni N, Jin X, Wang G, Li J, Zheng X, Zhang Y, Xu J, Yi S, Li X. LncMAP: Pan-cancer atlas of long noncoding RNA-mediated transcriptional network perturbations. Nucleic Acids Research. PMID 29325141 DOI: 10.1093/nar/gkx1311  0.88
2017 Li Y, Sahni N, Pancsa R, McGrail DJ, Xu J, Hua X, Coulombe-Huntington J, Ryan M, Tychhon B, Sudhakar D, Hu L, Tyers M, Jiang X, Lin SY, Babu MM, et al. Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer. Cell Reports. 21: 798-812. PMID 29045845 DOI: 10.1016/j.celrep.2017.09.071  0.88
2017 Yi S, Liu NN, Hu L, Wang H, Sahni N. Base-resolution stratification of cancer mutations using functional variomics. Nature Protocols. 12: 2323-2341. PMID 28981122 DOI: 10.1038/nprot.2017.086  0.88
2017 Yi S, Sahni N. Regulome Networks and Mutational Landscape in Liver Cancer: An Informative Path to Precision Medicine. Hepatology (Baltimore, Md.). PMID 28422313 DOI: 10.1002/hep.29220  0.88
2017 Yi S, Lin S, Li Y, Zhao W, Mills GB, Sahni N. Functional variomics and network perturbation: connecting genotype to phenotype in cancer. Nature Reviews. Genetics. PMID 28344341 DOI: 10.1038/nrg.2017.8  0.88
2017 Karras GI, Yi S, Sahni N, Fischer M, Xie J, Vidal M, D'Andrea AD, Whitesell L, Lindquist S. HSP90 Shapes the Consequences of Human Genetic Variation. Cell. PMID 28215707 DOI: 10.1016/j.cell.2017.01.023  0.88
2017 Chung CY, Khurana V, Yi S, Sahni N, Loh KH, Auluck PK, Baru V, Udeshi ND, Freyzon Y, Carr SA, Hill DE, Vidal M, Ting AY, Lindquist S. In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons. Cell Systems. PMID 28131823 DOI: 10.1016/j.cels.2017.01.002  0.88
2016 Li Y, Sahni N, Yi S. Comparative analysis of protein interactome networks prioritizes candidate genes with cancer signatures. Oncotarget. PMID 27791983 DOI: 10.18632/oncotarget.12879  0.88
2016 Yi S, Chen S, Zhang L, Sahni N. Signal Transduction and Regulation: Insights into Evolution. Biomed Research International. 2016: 8604245. PMID 27525280 DOI: 10.1155/2016/8604245  0.88
2016 Lin S, Yin YA, Jiang X, Sahni N, Yi S. Multi-OMICs and Genome Editing Perspectives on Liver Cancer Signaling Networks. Biomed Research International. 2016: 6186281. PMID 27403431 DOI: 10.1155/2016/6186281  0.88
2016 Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, et al. Pooled-matrix protein interaction screens using Barcode Fusion Genetics. Molecular Systems Biology. 12: 863. PMID 27107012  0.88
2016 Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, et al. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science (New York, N.Y.). 351: 1450-4. PMID 27013732 DOI: 10.1126/science.aad2257  0.88
2016 Sun S, Yang F, Tan G, Costanzo M, Oughtred R, Hirschman J, Theesfeld C, Bansal P, Sahni N, Yi S, Yu A, Tyagi T, Tie C, Hill DE, Vidal M, et al. An extended set of yeast-based functional assays accurately identifies human disease mutations. Genome Research. PMID 26975778 DOI: 10.1101/gr.192526.115  0.88
2016 Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, ... ... Sahni N, et al. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell. 164: 805-817. PMID 26871637 DOI: 10.1016/j.cell.2016.01.029  0.88
2016 Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, et al. Pooled-matrix protein interaction screens using Barcode Fusion Genetics Molecular Systems Biology. 12. DOI: 10.15252/msb.20156660  0.88
2015 Fuxman Bass JI, Sahni N, Shrestha S, Garcia-Gonzalez A, Mori A, Bhat N, Yi S, Hill DE, Vidal M, Walhout AJ. Human gene-centered transcription factor networks for enhancers and disease variants. Cell. 161: 661-73. PMID 25910213 DOI: 10.1016/j.cell.2015.03.003  0.88
2015 Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, et al. Widespread macromolecular interaction perturbations in human genetic disorders. Cell. 161: 647-60. PMID 25910212 DOI: 10.1016/j.cell.2015.04.013  0.88
2015 Sharma A, Menche J, Huang CC, Ort T, Zhou X, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Ghiassian SD, Gulbahce N, Baribaud F, Tocker J, Dobrin R, et al. A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma. Human Molecular Genetics. 24: 3005-20. PMID 25586491 DOI: 10.1093/hmg/ddv001  0.88
2015 Wang Y, Sahni N, Vidal M. Global Edgetic Rewiring in Cancer Networks Cell Systems. 1: 251-253. DOI: 10.1016/j.cels.2015.10.006  0.88
2014 Rolland T, TaÅŸan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, et al. A proteome-scale map of the human interactome network. Cell. 159: 1212-26. PMID 25416956 DOI: 10.1016/j.cell.2014.10.050  0.88
2014 Hill SJ, Rolland T, Adelmant G, Xia X, Owen MS, Dricot A, Zack TI, Sahni N, Jacob Y, Hao T, McKinney KM, Clark AP, Reyon D, Tsai SQ, Joung JK, et al. Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage. Genes & Development. 28: 1957-75. PMID 25184681 DOI: 10.1101/gad.241620.114  0.88
2014 Dittmer TA, Sahni N, Kubben N, Hill DE, Vidal M, Burgess RC, Roukos V, Misteli T. Systematic identification of pathological lamin A interactors. Molecular Biology of the Cell. 25: 1493-510. PMID 24623722 DOI: 10.1091/mbc.E14-02-0733  0.88
2013 Sahni N, Yi S, Zhong Q, Jailkhani N, Charloteaux B, Cusick ME, Vidal M. Edgotype: a fundamental link between genotype and phenotype. Current Opinion in Genetics & Development. 23: 649-57. PMID 24287335 DOI: 10.1016/j.gde.2013.11.002  0.88
2012 Srikantha T, Daniels KJ, Pujol C, Sahni N, Yi S, Soll DR. Nonsex genes in the mating type locus of Candida albicans play roles in a/α biofilm formation, including impermeability and fluconazole resistance. Plos Pathogens. 8: e1002476. PMID 22253594 DOI: 10.1371/journal.ppat.1002476  0.88
2011 Yi S, Sahni N, Daniels KJ, Lu KL, Srikantha T, Huang G, Garnaas AM, Soll DR. Alternative mating type configurations (a/α versus a/a or α/α) of Candida albicans result in alternative biofilms regulated by different pathways. Plos Biology. 9: e1001117. PMID 21829325 DOI: 10.1371/journal.pbio.1001117  0.88
2011 Yi S, Sahni N, Daniels KJ, Lu KL, Huang G, Srikantha T, Soll DR. Self-induction of a/a or alpha/alpha biofilms in Candida albicans is a pheromone-based paracrine system requiring switching. Eukaryotic Cell. 10: 753-60. PMID 21498642 DOI: 10.1128/EC.05055-11  0.88
2011 Yi S, Sahni N, Daniels KJ, Lu KL, Huang G, Garnaas AM, Pujol C, Srikantha T, Soll DR. Utilization of the mating scaffold protein in the evolution of a new signal transduction pathway for biofilm development. Mbio. 2: e00237-10. PMID 21221248 DOI: 10.1128/mBio.00237-10  0.88
2010 Sahni N, Yi S, Daniels KJ, Huang G, Srikantha T, Soll DR. Tec1 mediates the pheromone response of the white phenotype of Candida albicans: insights into the evolution of new signal transduction pathways. Plos Biology. 8: e1000363. PMID 20454615 DOI: 10.1371/journal.pbio.1000363  0.88
2010 Huang G, Yi S, Sahni N, Daniels KJ, Srikantha T, Soll DR. N-acetylglucosamine induces white to opaque switching, a mating prerequisite in Candida albicans. Plos Pathogens. 6: e1000806. PMID 20300604 DOI: 10.1371/journal.ppat.1000806  0.88
2009 Sahni N, Yi S, Daniels KJ, Srikantha T, Pujol C, Soll DR. Genes selectively up-regulated by pheromone in white cells are involved in biofilm formation in Candida albicans. Plos Pathogens. 5: e1000601. PMID 19798425 DOI: 10.1371/journal.ppat.1000601  0.88
2009 Huang G, Srikantha T, Sahni N, Yi S, Soll DR. CO(2) regulates white-to-opaque switching in Candida albicans. Current Biology : Cb. 19: 330-4. PMID 19200725 DOI: 10.1016/j.cub.2009.01.018  0.88
2009 Yi S, Sahni N, Pujol C, Daniels KJ, Srikantha T, Ma N, Soll DR. A Candida albicans-specific region of the alpha-pheromone receptor plays a selective role in the white cell pheromone response. Molecular Microbiology. 71: 925-47. PMID 19170873 DOI: 10.1111/j.1365-2958.2008.06575.x  0.88
2009 Sahni N, Yi S, Pujol C, Soll DR. The white cell response to pheromone is a general characteristic of Candida albicans strains. Eukaryotic Cell. 8: 251-6. PMID 19074600 DOI: 10.1128/EC.00320-08  0.88
2008 Srikantha T, Daniels KJ, Wu W, Lockhart SR, Yi S, Sahni N, Ma N, Soll DR. Dark brown is the more virulent of the switch phenotypes of Candida glabrata. Microbiology (Reading, England). 154: 3309-18. PMID 18957584 DOI: 10.1099/mic.0.2008/020578-0  0.88
2008 Yi S, Sahni N, Daniels KJ, Pujol C, Srikantha T, Soll DR. The same receptor, G protein, and mitogen-activated protein kinase pathway activate different downstream regulators in the alternative white and opaque pheromone responses of Candida albicans. Molecular Biology of the Cell. 19: 957-70. PMID 18162580 DOI: 10.1091/mbc.E07-07-0688  0.88
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