Insuk Lee, Ph.D. - Publications

2002 University of Texas at Austin, Austin, Texas, U.S.A. 
Molecular Biology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Cho A, Shim JE, Kim E, Supek F, Lehner B, Lee I. MUFFINN: cancer gene discovery via network analysis of somatic mutation data. Genome Biology. 17: 129. PMID 27333808 DOI: 10.1186/s13059-016-0989-x  1
2016 Shim JE, Lee I. Weighted mutual information analysis substantially improves domain-based functional network models. Bioinformatics (Oxford, England). PMID 27207946 DOI: 10.1093/bioinformatics/btw320  1
2016 Hwang S, Kim CY, Ji SG, Go J, Kim H, Yang S, Kim HJ, Cho A, Yoon SS, Lee I. Network-assisted investigation of virulence and antibiotic-resistance systems in Pseudomonas aeruginosa. Scientific Reports. 6: 26223. PMID 27194047 DOI: 10.1038/srep26223  1
2015 Lee I, Kim E, Marcotte EM. Modes of interaction between individuals dominate the topologies of real world networks. Plos One. 10: e0121248. PMID 25793969 DOI: 10.1371/journal.pone.0121248  1
2015 Kim H, Jung KW, Maeng S, Chen YL, Shin J, Shim JE, Hwang S, Janbon G, Kim T, Heitman J, Bahn YS, Lee I. Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans. Scientific Reports. 5: 8767. PMID 25739925 DOI: 10.1038/srep08767  1
2015 Kim T, Dreher K, Nilo-Poyanco R, Lee I, Fiehn O, Lange BM, Nikolau BJ, Sumner L, Welti R, Wurtele ES, Rhee SY. Patterns of metabolite changes identified from large-scale gene perturbations in Arabidopsis using a genome-scale metabolic network. Plant Physiology. 167: 1685-98. PMID 25670818 DOI: 10.1104/pp.114.252361  1
2014 Hwang S, Kim E, Yang S, Marcotte EM, Lee I. MORPHIN: a web tool for human disease research by projecting model organism biology onto a human integrated gene network. Nucleic Acids Research. 42: W147-53. PMID 24861622 DOI: 10.1093/nar/gku434  1
2013 Lee I. Network approaches to the genetic dissection of phenotypes in animals and humans Animal Cells and Systems. 17: 75-79. DOI: 10.1080/19768354.2013.789076  1
2012 Wang PI, Hwang S, Kincaid RP, Sullivan CS, Lee I, Marcotte EM. RIDDLE: reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene network. Genome Biology. 13: R125. PMID 23268829 DOI: 10.1186/gb-2012-13-12-r125  1
2012 Quanbeck SM, Brachova L, Campbell AA, Guan X, Perera A, He K, Rhee SY, Bais P, Dickerson JA, Dixon P, Wohlgemuth G, Fiehn O, Barkan L, Lange I, Lange BM, ... Lee I, et al. Metabolomics as a Hypothesis-Generating Functional Genomics Tool for the Annotation of Arabidopsis thaliana Genes of "Unknown Function". Frontiers in Plant Science. 3: 15. PMID 22645570 DOI: 10.3389/fpls.2012.00015  1
2012 Chae L, Lee I, Shin J, Rhee SY. Towards understanding how molecular networks evolve in plants. Current Opinion in Plant Biology. 15: 177-84. PMID 22280840 DOI: 10.1016/j.pbi.2012.01.006  1
2011 Lee I, Seo YS, Coltrane D, Hwang S, Oh T, Marcotte EM, Ronald PC. Genetic dissection of the biotic stress response using a genome-scale gene network for rice. Proceedings of the National Academy of Sciences of the United States of America. 108: 18548-53. PMID 22042862 DOI: 10.1073/pnas.1110384108  1
2011 Hwang S, Rhee SY, Marcotte EM, Lee I. Systematic prediction of gene function in Arabidopsis thaliana using a probabilistic functional gene network. Nature Protocols. 6: 1429-42. PMID 21886106 DOI: 10.1038/nprot.2011.372  1
2011 Lee I, Blom UM, Wang PI, Shim JE, Marcotte EM. Prioritizing candidate disease genes by network-based boosting of genome-wide association data. Genome Research. 21: 1109-21. PMID 21536720 DOI: 10.1101/gr.118992.110  1
2011 Seo YS, Chern M, Bartley LE, Han M, Jung KH, Lee I, Walia H, Richter T, Xu X, Cao P, Bai W, Ramanan R, Amonpant F, Arul L, Canlas PE, et al. Towards establishment of a rice stress response interactome. Plos Genetics. 7: e1002020. PMID 21533176 DOI: 10.1371/journal.pgen.1002020  1
2011 Lee I. Probabilistic functional gene societies. Progress in Biophysics and Molecular Biology. 106: 435-42. PMID 21281658 DOI: 10.1016/j.pbiomolbio.2011.01.003  1
2010 Huang N, Lee I, Marcotte EM, Hurles ME. Characterising and predicting haploinsufficiency in the human genome. Plos Genetics. 6: e1001154. PMID 20976243 DOI: 10.1371/journal.pgen.1001154  1
2010 Lee I, Lehner B, Vavouri T, Shin J, Fraser AG, Marcotte EM. Predicting genetic modifier loci using functional gene networks. Genome Research. 20: 1143-53. PMID 20538624 DOI: 10.1101/gr.102749.109  1
2010 Lee I, Ambaru B, Thakkar P, Marcotte EM, Rhee SY. Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana. Nature Biotechnology. 28: 149-56. PMID 20118918 DOI: 10.1038/nbt.1603  1
2009 Li Z, Lee I, Moradi E, Hung NJ, Johnson AW, Marcotte EM. Rational extension of the ribosome biogenesis pathway using network-guided genetics. Plos Biology. 7: e1000213. PMID 19806183 DOI: 10.1371/journal.pbio.1000213  1
2009 Gray RS, Abitua PB, Wlodarczyk BJ, Szabo-Rogers HL, Blanchard O, Lee I, Weiss GS, Liu KJ, Marcotte EM, Wallingford JB, Finnell RH. The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nature Cell Biology. 11: 1225-32. PMID 19767740 DOI: 10.1038/ncb1966  1
2009 Lee I, Marcotte EM. Effects of functional bias on supervised learning of a gene network model. Methods in Molecular Biology (Clifton, N.J.). 541: 463-75. PMID 19381535 DOI: 10.1007/978-1-59745-243-4_20  1
2008 Lee I, Marcotte EM. Integrating functional genomics data. Methods in Molecular Biology (Clifton, N.J.). 453: 267-78. PMID 18712309 DOI: 10.1007/978-1-60327-429-6_14  1
2008 Lehner B, Lee I. Network-guided genetic screening: building, testing and using gene networks to predict gene function. Briefings in Functional Genomics & Proteomics. 7: 217-27. PMID 18445637 DOI: 10.1093/bfgp/eln020  1
2008 Lee I, Lehner B, Crombie C, Wong W, Fraser AG, Marcotte EM. A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans. Nature Genetics. 40: 181-8. PMID 18223650 DOI: 10.1038/ng.2007.70  1
2007 McGary KL, Lee I, Marcotte EM. Broad network-based predictability of Saccharomyces cerevisiae gene loss-of-function phenotypes. Genome Biology. 8: R258. PMID 18053250 DOI: 10.1186/gb-2007-8-12-r258  1
2007 Lee I, Li Z, Marcotte EM. An improved, bias-reduced probabilistic functional gene network of baker's yeast, Saccharomyces cerevisiae. Plos One. 2: e988. PMID 17912365 DOI: 10.1371/journal.pone.0000988  1
2007 Hart GT, Lee I, Marcotte ER. A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality. Bmc Bioinformatics. 8: 236. PMID 17605818 DOI: 10.1186/1471-2105-8-236  1
2004 Lee I, Date SV, Adai AT, Marcotte EM. A probabilistic functional network of yeast genes. Science (New York, N.Y.). 306: 1555-8. PMID 15567862 DOI: 10.1126/science.1099511  1
2004 Bork P, Jensen LJ, von Mering C, Ramani AK, Lee I, Marcotte EM. Protein interaction networks from yeast to human. Current Opinion in Structural Biology. 14: 292-9. PMID 15193308 DOI: 10.1016/  1
2003 Lee I, Harshey RM. Patterns of sequence conservation at termini of long terminal repeat (LTR) retrotransposons and DNA transposons in the human genome: lessons from phage Mu. Nucleic Acids Research. 31: 4531-40. PMID 12888514  1
2003 Lee I, Harshey RM. The conserved CA/TG motif at Mu termini: T specifies stable transpososome assembly. Journal of Molecular Biology. 330: 261-75. PMID 12823966 DOI: 10.1016/S0022-2836(03)00574-6  1
2001 Lee I, Harshey RM. Importance of the conserved CA dinucleotide at Mu termini. Journal of Molecular Biology. 314: 433-44. PMID 11846557 DOI: 10.1006/jmbi.2001.5177  1
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