Jennifer A. Pietenpol - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Cell Biology, Molecular Biology, Microbiology Biology

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Redman-Rivera LN, Shaver TM, Jin H, Marshall CB, Schafer JM, Sheng Q, Hongo RA, Beckermann KE, Wheeler FC, Lehmann BD, Pietenpol JA. Acquisition of aneuploidy drives mutant p53-associated gain-of-function phenotypes. Nature Communications. 12: 5184. PMID 34465782 DOI: 10.1038/s41467-021-25359-z  0.393
2021 Marshall CB, Beeler JS, Lehmann BD, Gonzalez-Ericsson P, Sanchez V, Sanders ME, Boyd KL, Pietenpol JA. Tissue-specific expression of p73 and p63 isoforms in human tissues. Cell Death & Disease. 12: 745. PMID 34315849 DOI: 10.1038/s41419-021-04017-8  0.316
2020 Schafer JM, Pietenpol JA. Tyramide Signal-Amplified Immunofluorescence of MYCN and MYC in Human Tissue Specimens and Cell Line Cultures. Bio-Protocol. 10: e3677. PMID 33659347 DOI: 10.21769/BioProtoc.3677  0.308
2020 Schafer JM, Lehmann BD, Gonzalez-Ericsson PI, Marshall CB, Beeler JS, Redman LN, Jin H, Sanchez V, Stubbs MC, Scherle P, Johnson KN, Sheng Q, Roland JT, Bauer JA, Shyr Y, ... ... Pietenpol JA, et al. Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors. Science Translational Medicine. 12. PMID 32161105 DOI: 10.1126/Scitranslmed.Aaw8275  0.363
2020 Lander EM, Lehmann BD, Shah PD, Dees EC, Ballinger TJ, Pohlmann PR, Santa-Maria CA, Shyr Y, Mayer IA, Park BH, Pietenpol JA, Abramson VG. A phase II trial of atezolizumab (anti-PD-L1) with carboplatin in patients with metastatic triple-negative breast cancer (mTNBC). Journal of Clinical Oncology. 38: TPS1112-TPS1112. DOI: 10.1200/Jco.2020.38.15_Suppl.Tps1112  0.311
2019 Beeler JS, Marshall CB, Gonzalez-Ericsson PI, Shaver TM, Santos Guasch GL, Lea ST, Johnson KN, Jin H, Venters BJ, Sanders ME, Pietenpol JA. p73 regulates epidermal wound healing and induced keratinocyte programming. Plos One. 14: e0218458. PMID 31216312 DOI: 10.1371/Journal.Pone.0218458  0.501
2019 Lehmann BD, Shaver TM, Johnson DB, Li Z, Gonzalez-Ericsson PI, Sanchez V, Shyr Y, Sanders ME, Pietenpol JA. Identification of targetable recurrent MAP3K8 rearrangements in melanomas lacking known driver mutations. Molecular Cancer Research : McR. PMID 31186280 DOI: 10.1158/1541-7786.Mcr-19-0257  0.361
2019 Gonzalez-Ericsson P, Lehmann B, Mobley B, Chen Y, Pietenpol J, Sanders M. Abstract P2-06-09: Identification of oncogenic gene fusions in triple-negative breast cancer metastatic to the brain Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P2-06-09  0.441
2019 Lehmann BD, Colaprico A, Chen J, Wang L, Pietenpol J, Chen X. Abstract LB-301: Integrative genomic analysis identifies distinct mutational, epigenetic and immunological patterns among triple-negative breast cancer subtypes Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-301  0.384
2018 Richmond BW, Du RH, Marshall C, Pietenpol J, Polosukhin VV, Blackwell TS. p73 Is Required for pIgR Expression in the Respiratory Epithelium. Annals of the American Thoracic Society. 15: S290. PMID 30759000 DOI: 10.1513/Annalsats.201806-410Mg  0.3
2018 Fuertes-Alvarez S, Maeso-Alonso L, Villoch-Fernandez J, Wildung M, Martin-Lopez M, Marshall C, Villena-Cortes AJ, Diez-Prieto I, Pietenpol JA, Tissir F, Lizé M, Marques MM, Marin MC. p73 regulates ependymal planar cell polarity by modulating actin and microtubule cytoskeleton. Cell Death & Disease. 9: 1183. PMID 30518789 DOI: 10.1038/S41419-018-1205-6  0.386
2018 Santos Guasch GL, Beeler JS, Marshall CB, Shaver TM, Sheng Q, Johnson KN, Boyd KL, Venters BJ, Cook RS, Pietenpol JA. p73 Is Required for Ovarian Follicle Development and Regulates a Gene Network Involved in Cell-to-Cell Adhesion. Iscience. 8: 236-249. PMID 30340069 DOI: 10.1016/J.Isci.2018.09.018  0.529
2018 Schafer J, Lehmann B, Redman L, Liu P, Stubbs M, Ruggeri B, Scherle P, Pietenpol J. Abstract P2-09-24: Combination treatment with bromodomain and extra-terminal motif inhibitors in triple-negative breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P2-09-24  0.375
2017 Jovanović B, Sheng Q, Seitz RS, Lawrence KD, Morris SW, Thomas LR, Hout DR, Schweitzer BL, Guo Y, Pietenpol JA, Lehmann BD. Comparison of triple-negative breast cancer molecular subtyping using RNA from matched fresh-frozen versus formalin-fixed paraffin-embedded tissue. Bmc Cancer. 17: 241. PMID 28376728 DOI: 10.1186/S12885-017-3237-1  0.362
2017 Jovanovic B, Mayer IA, Mayer EL, Abramson VG, Bardia A, Sanders M, Kuba MG, Estrada MV, Beeler JS, Shaver TM, Johnson KN, Sanchez V, Rosenbluth JM, Dillon PM, Forrero-Torres A, ... ... Pietenpol JA, et al. A randomized phase II neoadjuvant study of cisplatin, paclitaxel with or without everolimus in patients with stage II/III triple-negative breast cancer (TNBC). Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28270498 DOI: 10.1158/1078-0432.Ccr-16-3055  0.716
2017 Liu PCC, Lehmann BD, Ruggeri B, DiMatteo D, Schafer JM, Lu J, Lee SH, Lin L, Burn TC, Diamond M, Volgina A, Wu L, Hollis G, Huber R, Pietenpol JA, et al. Abstract 531: Activity of the selective FGFR 1, 2 and 3 inhibitor INCB054828 in genetically-defined models of triple-negative breast cancer Cancer Research. 77: 531-531. DOI: 10.1158/1538-7445.Am2017-531  0.384
2017 Schafer J, Lehmann B, Liu P, Stubbs M, Scherle P, Pietenpol J. Abstract 1518: Mechanisms of bromodomain and extra-terminal motif inhibitor (BETi) sensitivity in triple-negative breast cancer (TNBC) Cancer Research. 77: 1518-1518. DOI: 10.1158/1538-7445.Am2017-1518  0.354
2016 Cowen SD, Russell D, Dakin LA, Chen H, Larsen NA, Godin R, Throner S, Zheng X, Molina A, Wu J, Cheung T, Howard T, Garcia-Arenas R, Keen N, Pendleton CS, ... Pietenpol JA, et al. Design, Synthesis, and Biological Activity of Substrate Competitive SMYD2 Inhibitors. Journal of Medicinal Chemistry. 59: 11079-11097. PMID 28002961 DOI: 10.1021/Acs.Jmedchem.6B01303  0.343
2016 Ludwik KA, Campbell JP, Li M, Li Y, Sandusky ZM, Pasic L, Sowder ME, Brenin DR, Pietenpol JA, O'Doherty GA, Lannigan DA. Development of a RSK Inhibitor as a Novel Therapy for Triple Negative Breast Cancer. Molecular Cancer Therapeutics. PMID 27528706 DOI: 10.1158/1535-7163.Mct-16-0106  0.325
2016 Lehmann BD, Jovanović B, Chen X, Estrada MV, Johnson KN, Shyr Y, Moses HL, Sanders ME, Pietenpol JA. Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection. Plos One. 11: e0157368. PMID 27310713 DOI: 10.1371/Journal.Pone.0157368  0.336
2016 Shaver TM, Lehmann BD, Beeler JS, Li CI, Li Z, Jin H, Stricker TP, Shyr Y, Pietenpol JA. Diverse, Biologically Relevant, and Targetable Gene Rearrangements in Triple-Negative Breast Cancer and Other Malignancies. Cancer Research. PMID 27231203 DOI: 10.1158/0008-5472.Can-16-0058  0.378
2016 Marshall CB, Mays DJ, Beeler JS, Rosenbluth JM, Boyd KL, Santos Guasch GL, Shaver TM, Tang LJ, Liu Q, Shyr Y, Venters BJ, Magnuson MA, Pietenpol JA. p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network. Cell Reports. PMID 26947080 DOI: 10.1016/J.Celrep.2016.02.035  0.817
2016 Ring BZ, Hout DR, Morris SW, Lawrence K, Schweitzer BL, Bailey DB, Lehmann BD, Pietenpol JA, Seitz RS. Generation of an algorithm based on minimal gene sets to clinically subtype triple negative breast cancer patients. Bmc Cancer. 16: 143. PMID 26908167 DOI: 10.1186/S12885-016-2198-0  0.304
2015 Wilson AJ, Fadare O, Beeghly-Fadiel A, Son DS, Liu Q, Zhao S, Saskowski J, Uddin MJ, Daniel C, Crews B, Lehmann BD, Pietenpol JA, Crispens MA, Marnett LJ, Khabele D. Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer. Oncotarget. PMID 25972361 DOI: 10.18632/Oncotarget.3860  0.386
2015 Mohni KN, Thompson PS, Luzwick JW, Glick GG, Pendleton CS, Lehmann BD, Pietenpol JA, Cortez D. A Synthetic Lethal Screen Identifies DNA Repair Pathways that Sensitize Cancer Cells to Combined ATR Inhibition and Cisplatin Treatments. Plos One. 10: e0125482. PMID 25965342 DOI: 10.1371/Journal.Pone.0125482  0.338
2015 Wilson AJ, Lehmann BD, Liu Q, Uddin J, Elleman A, Crews B, Saskowski J, Pietenpol J, Marnett LJ, Khabele D. Abstract POSTER-BIOL-1350: Dissecting cellular and molecular consequences of disrupting cyclooxygenase-1 activity in ovarian cancer Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-Poster-Biol-1350  0.407
2015 Seitz RS, Hout DR, Morris SW, Smith RB, Lehmann BD, Chen X, Pietenpol JA, Ring BZ. Abstract P6-08-04: Creation of a robust algorithm utilizing minimal gene sets normalized against a reference gene set to identify triple-negative breast cancer (TNBC) subtypes Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P6-08-04  0.378
2015 Jovanovic B, Beeler JS, Pickup MW, Chytil A, Gorska AE, Ashby WJ, Lehmann BD, Zijlstra A, Pietenpol JA, Moses HL. Abstract P6-03-04: TGF-β receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P6-03-04  0.412
2015 Lehmann BD, Bauer JA, Schafer JM, Pendleton CS, Tang L, Johnson KC, Chen X, Balko JM, Gomez H, Arteaga CL, Mills GB, Sanders ME, Pietenpol JA. Abstract P3-04-03: PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-04-03  0.344
2015 Wilson AJ, Lehmann BD, Saskowski J, Uddin J, Daniel C, Crews BC, Liu Q, Zhao S, Son D, Pietenpol JA, Marnett LJ, Khabele D. Abstract 2068: Cyclooxygenase-1 gene expression contributes to multiple oncogenic pathways in high grade serous ovarian cancer Cancer Research. 75: 2068-2068. DOI: 10.1158/1538-7445.Am2015-2068  0.401
2014 Lehmann BD, Bauer JA, Schafer JM, Pendleton CS, Tang L, Johnson KC, Chen X, Balko JM, Gómez H, Arteaga CL, Mills GB, Sanders ME, Pietenpol JA. PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors. Breast Cancer Research : Bcr. 16: 406. PMID 25103565 DOI: 10.1186/S13058-014-0406-X  0.328
2014 Jovanovi? B, Beeler JS, Pickup MW, Chytil A, Gorska AE, Ashby WJ, Lehmann BD, Zijlstra A, Pietenpol JA, Moses HL. Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer. Breast Cancer Research : Bcr. 16: R69. PMID 24985072 DOI: 10.1186/Bcr3684  0.407
2014 Feigin ME, Akshinthala SD, Araki K, Rosenberg AZ, Muthuswamy LB, Martin B, Lehmann BD, Berman HK, Pietenpol JA, Cardiff RD, Muthuswamy SK. Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer. Cancer Research. 74: 3180-94. PMID 24662921 DOI: 10.1158/0008-5472.Can-13-3415  0.429
2014 Balko JM, Giltnane JM, Wang K, Schwarz LJ, Young CD, Cook RS, Owens P, Sanders ME, Kuba MG, Sánchez V, Kurupi R, Moore PD, Pinto JA, Doimi FD, Gómez H, ... ... Pietenpol JA, et al. Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets. Cancer Discovery. 4: 232-45. PMID 24356096 DOI: 10.1158/2159-8290.Cd-13-0286  0.356
2014 Lehmann BD, Pietenpol JA. Identification and use of biomarkers in treatment strategies for triple-negative breast cancer subtypes. The Journal of Pathology. 232: 142-50. PMID 24114677 DOI: 10.1002/Path.4280  0.317
2014 Abramson VG, Lehmann B, Mayer IA, Arteaga CL, Pietenpol JA. TBCRC028: A phase Ib/II trial of GDC-0941 (a PI3K inhibitor) in combination with cisplatin in metastatic androgen receptor-negative triple-negative breast cancer (TNBC). Journal of Clinical Oncology. 32. DOI: 10.1200/Jco.2014.32.15_Suppl.Tps1148  0.347
2014 Wilson AJ, Lehmann BD, Ussin J, Elleman A, Crews B, Saskowski J, Pietenpol J, Marnett LJ, Khabele D. Abstract 4928: Cyclooxygenase-1 as a target for molecular imaging of high grade serous ovarian cancer Cancer Research. 74: 4928-4928. DOI: 10.1158/1538-7445.Am2014-4928  0.372
2013 Yu KD, Zhu R, Zhan M, Rodriguez AA, Yang W, Wong S, Makris A, Lehmann BD, Chen X, Mayer I, Pietenpol JA, Shao ZM, Symmans WF, Chang JC. Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 2723-33. PMID 23549873 DOI: 10.1158/1078-0432.Ccr-12-2986  0.306
2013 Landis MD, Lehmann BD, Pietenpol JA, Chang JC. Patient-derived breast tumor xenografts facilitating personalized cancer therapy. Breast Cancer Research : Bcr. 15: 201. PMID 23339383 DOI: 10.1186/Bcr3355  0.311
2013 Masuda H, Baggerly KA, Wang Y, Zhang Y, Gonzalez-Angulo AM, Meric-Bernstam F, Valero V, Lehmann BD, Pietenpol JA, Hortobagyi GN, Symmans WF, Ueno NT. Differential pathologic complete response rates after neoadjuvant chemotherapy among molecular subtypes of triple-negative breast cancer. Journal of Clinical Oncology. 31: 1005-1005. DOI: 10.1200/Jco.2013.31.15_Suppl.1005  0.338
2013 Jovanovic B, Chen SX, Lehmann BD, Johnson KN, Sanchez V, Kuba MG, Sanders ME, Mayer IA, Moses HL, Pietenpol JA. Abstract 4698: Gene expression profiles of triple negative breast cancer epithelial and stromal cells are predictive of treatment response. Cancer Research. 73: 4698-4698. DOI: 10.1158/1538-7445.Am2013-4698  0.342
2013 Mayer I, Jovanovic B, Abramson V, Mayer E, Sanders M, Bardia A, Dillon P, Kuba M, Carpenter J, Chang J, Lehmann B, Meszoely I, Grau A, Shyr Y, Arteaga C, ... ... Pietenpol J, et al. Abstract PD1-6: A randomized phase II neoadjuvant study of cisplatin, paclitaxel with or without everolimus (an mTOR inhibitor) in patients with stage II/III triple-negative breast cancer (TNBC) Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-Pd1-6  0.367
2012 Lehmann BD, Pietenpol JA. Targeting mutant p53 in human tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 3648-50. PMID 22965952 DOI: 10.1200/Jco.2012.44.0412  0.557
2012 Chen X, Li J, Gray WH, Lehmann BD, Bauer JA, Shyr Y, Pietenpol JA. TNBCtype: A Subtyping Tool for Triple-Negative Breast Cancer. Cancer Informatics. 11: 147-56. PMID 22872785 DOI: 10.4137/Cin.S9983  0.312
2012 Lehmann B, Bauer J, Schafer J, Tang L, Pendleton C, Sanders M, Pietenpol J. Abstract P6-05-03: Targeted inhibition of recurrent PIK3CA mutations synergizes with bicalutamide in AR-expressing triple negative breast cancer Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P6-05-03  0.412
2012 Jovanovic B, Ashby W, Zijlstra A, Pietenpol J, Moses H. Abstract P3-05-09: The role of TGF-beta receptor type 3 in breast cancer progression Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P3-05-09  0.381
2012 Pietenpol J. Abstract ES2-2: Triple Negative Breast Cancer: Subtypes, Molecular Targets, and Therapeutic Approaches Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-Es2-2  0.371
2011 Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y, Pietenpol JA. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. The Journal of Clinical Investigation. 121: 2750-67. PMID 21633166 DOI: 10.1172/Jci45014  0.384
2011 Rosenbluth JM, Mays DJ, Jiang A, Shyr Y, Pietenpol JA. Differential regulation of the p73 cistrome by mammalian target of rapamycin reveals transcriptional programs of mesenchymal differentiation and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 2076-81. PMID 21245298 DOI: 10.1073/Pnas.1011936108  0.816
2011 Bauer JA, Lehmann BD, Glick G, Cortez D, Lee E, Pietenpol JA. Abstract 951: Loss-of-function screening identifies therapeutic targets for triple negative breast cancer (TNBC) Cancer Research. 71: 951-951. DOI: 10.1158/1538-7445.Am2011-951  0.443
2011 Lehmann BD, Bauer JA, Sanders ME, Chakravarthy BA, Pietenpol JA. Abstract 4411: γH2AX as a marker of genomic instability predicts cisplatin sensitivity in triple negative breast cancer cells Cancer Research. 71: 4411-4411. DOI: 10.1158/1538-7445.Am2011-4411  0.379
2011 Mayer I, Means-Powell J, Abramson V, Shyr Y, Balko J, Kuba M, Gharavi H, Schlabach L, Arteaga C, Pietenpol J. PD09-06: Phase II Trial of RAD001 (Everolimus), an mTOR Inhibitor, with Weekly Cisplatin and Paclitaxel in Patients with HER2−Negative Metastatic Breast Cancer (MBC). Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-Pd09-06  0.451
2010 Barton CE, Johnson KN, Mays DM, Boehnke K, Shyr Y, Boukamp P, Pietenpol JA. Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation. Cell Death & Disease. 1: e74. PMID 21151771 DOI: 10.1038/Cddis.2010.49  0.75
2010 Adams S, Chakravarthy AB, Donach M, Spicer D, Lymberis S, Singh B, Bauer JA, Hochman T, Goldberg JD, Muggia F, Schneider RJ, Pietenpol JA, Formenti SC. Preoperative concurrent paclitaxel-radiation in locally advanced breast cancer: pathologic response correlates with five-year overall survival. Breast Cancer Research and Treatment. 124: 723-32. PMID 20878462 DOI: 10.1007/S10549-010-1181-8  0.304
2010 Bauer JA, Ye F, Marshall CB, Lehmann BD, Pendleton CS, Shyr Y, Arteaga CL, Pietenpol JA. RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells. Breast Cancer Research : Bcr. 12: R41. PMID 20576088 DOI: 10.1186/Bcr2595  0.375
2010 Eby KG, Rosenbluth JM, Mays DJ, Marshall CB, Barton CE, Sinha S, Johnson KN, Tang L, Pietenpol JA. ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy. Molecular Cancer. 9: 95. PMID 20429933 DOI: 10.1186/1476-4598-9-95  0.781
2010 Bauer JA, Chakravarthy AB, Rosenbluth JM, Mi D, Seeley EH, De Matos Granja-Ingram N, Olivares MG, Kelley MC, Mayer IA, Meszoely IM, Means-Powell JA, Johnson KN, Tsai CJ, Ayers GD, Sanders ME, ... ... Pietenpol JA, et al. Identification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 681-90. PMID 20068102 DOI: 10.1158/1078-0432.Ccr-09-1091  0.738
2010 Mayer IA, Meszoely IM, Sanders M, Shyr Y, Abramson VG, Means-Powell JA, Chakravarthy AB, Arteaga CL, Pietenpol JA. A phase II neoadjuvant study of cisplatin/paclitaxel with or without RAD001 in patients with triple-negative (TN) locally advanced breast cancer (BC). Journal of Clinical Oncology. 28: TPS119-TPS119. DOI: 10.1200/Jco.2010.28.15_Suppl.Tps119  0.44
2010 Adams S, Lymberis SC, Chakravarthy AB, Spicer DV, Hochman T, Donach M, Goldberg JD, Schneider R, Pietenpol JA, Formenti S. Predictors of pathologic response and correlation with long-term outcomes in a trial of neoadjuvant concurrent paclitaxel radiation in locally advanced breast cancer (LABC). Journal of Clinical Oncology. 28: 589-589. DOI: 10.1200/Jco.2010.28.15_Suppl.589  0.347
2010 Formenti S, Adams S, Chakravarthy AB, Lymberis SC, Spicer DV, Bauer JA, Volm M, Roses D, Goldberg JD, Pietenpol JA. Five-year results of preoperative concurrent paclitaxel with radiation in locally advanced breast cancer (LABC). Journal of Clinical Oncology. 28: 567-567. DOI: 10.1200/Jco.2010.28.15_Suppl.567  0.341
2009 Rosenbluth JM, Johnson K, Tang L, Triplett T, Pietenpol JA. Evaluation of p63 and p73 antibodies for cross-reactivity. Cell Cycle (Georgetown, Tex.). 8: 3702-6. PMID 19855172 DOI: 10.4161/Cc.8.22.10036  0.795
2009 Barton CE, Tahinci E, Barbieri CE, Johnson KN, Hanson AJ, Jernigan KK, Chen TW, Lee E, Pietenpol JA. DeltaNp63 antagonizes p53 to regulate mesoderm induction in Xenopus laevis. Developmental Biology. 329: 130-9. PMID 19272371 DOI: 10.1016/J.Ydbio.2009.02.036  0.796
2009 Rosenbluth JM, Pietenpol JA. mTOR regulates autophagy-associated genes downstream of p73. Autophagy. 5: 114-6. PMID 19001857 DOI: 10.4161/Auto.5.1.7294  0.824
2008 Rosenbluth JM, Pietenpol JA. The jury is in: p73 is a tumor suppressor after all. Genes & Development. 22: 2591-5. PMID 18832062 DOI: 10.1101/Gad.1727408  0.794
2008 Brown KA, Ham AJ, Clark CN, Meller N, Law BK, Chytil A, Cheng N, Pietenpol JA, Moses HL. Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1. Journal of Cellular Biochemistry. 105: 596-611. PMID 18729074 DOI: 10.1002/Jcb.21860  0.319
2008 Rosenbluth JM, Mays DJ, Pino MF, Tang LJ, Pietenpol JA. A gene signature-based approach identifies mTOR as a regulator of p73. Molecular and Cellular Biology. 28: 5951-64. PMID 18678646 DOI: 10.1128/Mcb.00305-08  0.811
2007 Perez CA, Ott J, Mays DJ, Pietenpol JA. p63 consensus DNA-binding site: identification, analysis and application into a p63MH algorithm. Oncogene. 26: 7363-70. PMID 17563751 DOI: 10.1038/Sj.Onc.1210561  0.68
2007 Bonine-Summers AR, Aakre ME, Brown KA, Arteaga CL, Pietenpol JA, Moses HL, Cheng N. Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells. Cancer Biology & Therapy. 6: 561-70. PMID 17495520 DOI: 10.4161/Cbt.6.4.3851  0.33
2007 Schavolt KL, Pietenpol JA. p53 and Delta Np63 alpha differentially bind and regulate target genes involved in cell cycle arrest, DNA repair and apoptosis. Oncogene. 26: 6125-32. PMID 17404570 DOI: 10.1038/Sj.Onc.1210441  0.824
2007 Perez CA, Pietenpol JA. Transcriptional programs regulated by p63 in normal epithelium and tumors. Cell Cycle (Georgetown, Tex.). 6: 246-54. PMID 17297308 DOI: 10.4161/Cc.6.3.3801  0.732
2006 Barbieri CE, Tang LJ, Brown KA, Pietenpol JA. Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis. Cancer Research. 66: 7589-97. PMID 16885358 DOI: 10.1158/0008-5472.Can-06-2020  0.732
2006 Hinow P, Rogers CE, Barbieri CE, Pietenpol JA, Kenworthy AK, DiBenedetto E. The DNA binding activity of p53 displays reaction-diffusion kinetics. Biophysical Journal. 91: 330-42. PMID 16603489 DOI: 10.1529/Biophysj.105.078303  0.637
2006 Chakravarthy AB, Kelley MC, McLaren B, Truica CI, Billheimer D, Mayer IA, Grau AM, Johnson DH, Simpson JF, Beauchamp RD, Jones C, Pietenpol JA. Neoadjuvant concurrent paclitaxel and radiation in stage II/III breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1570-6. PMID 16533783 DOI: 10.1158/1078-0432.Ccr-05-2304  0.348
2006 Barbieri CE, Pietenpol JA. p63 and epithelial biology. Experimental Cell Research. 312: 695-706. PMID 16406339 DOI: 10.1016/J.Yexcr.2005.11.028  0.72
2005 Hearnes JM, Mays DJ, Schavolt KL, Tang L, Jiang X, Pietenpol JA. Chromatin immunoprecipitation-based screen to identify functional genomic binding sites for sequence-specific transactivators. Molecular and Cellular Biology. 25: 10148-58. PMID 16260627 DOI: 10.1128/Mcb.25.22.10148-10158.2005  0.757
2005 Barbieri CE, Pietenpol JA. p53 family members: similar biochemistry, different biology. Cancer Biology & Therapy. 4: 419-20. PMID 15908776 DOI: 10.4161/Cbt.4.4.1760  0.695
2005 Westfall MD, Joyner AS, Barbieri CE, Livingstone M, Pietenpol JA. Ultraviolet radiation induces phosphorylation and ubiquitin-mediated degradation of DeltaNp63alpha. Cell Cycle (Georgetown, Tex.). 4: 710-6. PMID 15846104 DOI: 10.4161/Cc.4.5.1685  0.838
2005 Maas K, Westfall M, Pietenpol J, Olsen NJ, Aune T. Reduced p53 in peripheral blood mononuclear cells from patients with rheumatoid arthritis is associated with loss of radiation-induced apoptosis. Arthritis and Rheumatism. 52: 1047-57. PMID 15818671 DOI: 10.1002/Art.20931  0.775
2005 Barbieri CE, Perez CA, Johnson KN, Ely KA, Billheimer D, Pietenpol JA. IGFBP-3 is a direct target of transcriptional regulation by DeltaNp63alpha in squamous epithelium. Cancer Research. 65: 2314-20. PMID 15781645 DOI: 10.1158/0008-5472.Can-04-3449  0.765
2004 Sniezek JC, Matheny KE, Westfall MD, Pietenpol JA. Dominant negative p63 isoform expression in head and neck squamous cell carcinoma. The Laryngoscope. 114: 2063-72. PMID 15564824 DOI: 10.1097/01.Mlg.0000149437.35855.4B  0.803
2004 Brown KA, Aakre ME, Gorska AE, Price JO, Eltom SE, Pietenpol JA, Moses HL. Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro. Breast Cancer Research : Bcr. 6: R215-31. PMID 15084245 DOI: 10.1186/Bcr778  0.31
2004 Westfall MD, Pietenpol JA. p63: Molecular complexity in development and cancer. Carcinogenesis. 25: 857-64. PMID 15033906 DOI: 10.1093/Carcin/Bgh148  0.831
2003 Massion PP, Taflan PM, Jamshedur Rahman SM, Yildiz P, Shyr Y, Edgerton ME, Westfall MD, Roberts JR, Pietenpol JA, Carbone DP, Gonzalez AL. Significance of p63 amplification and overexpression in lung cancer development and prognosis. Cancer Research. 63: 7113-21. PMID 14612504  0.765
2003 Barbieri CE, Barton CE, Pietenpol JA. Delta Np63 alpha expression is regulated by the phosphoinositide 3-kinase pathway. The Journal of Biological Chemistry. 278: 51408-14. PMID 14555649 DOI: 10.1074/Jbc.M309943200  0.717
2003 Jo D, Lin Q, Nashabi A, Mays DJ, Unutmaz D, Pietenpol JA, Ruley HE. Cell cycle-dependent transduction of cell-permeant Cre recombinase proteins. Journal of Cellular Biochemistry. 89: 674-87. PMID 12858334 DOI: 10.1002/Jcb.10542  0.364
2003 Matheny KE, Barbieri CE, Sniezek JC, Arteaga CL, Pietenpol JA. Inhibition of epidermal growth factor receptor signaling decreases p63 expression in head and neck squamous carcinoma cells. The Laryngoscope. 113: 936-9. PMID 12782800 DOI: 10.1097/00005537-200306000-00004  0.699
2003 Westfall MD, Mays DJ, Sniezek JC, Pietenpol JA. The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Molecular and Cellular Biology. 23: 2264-76. PMID 12640112 DOI: 10.1128/Mcb.23.7.2264-2276.2003  0.804
2003 Stewart ZA, Westfall MD, Pietenpol JA. Cell-cycle dysregulation and anticancer therapy. Trends in Pharmacological Sciences. 24: 139-45. PMID 12628359 DOI: 10.1016/S0165-6147(03)00026-9  0.806
2003 Anwar A, Dehn D, Siegel D, Kepa JK, Tang LJ, Pietenpol JA, Ross D. Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems. The Journal of Biological Chemistry. 278: 10368-73. PMID 12529318 DOI: 10.1074/Jbc.M211981200  0.538
2002 Pietenpol JA, Stewart ZA. Cell cycle checkpoint signaling: cell cycle arrest versus apoptosis. Toxicology. 181: 475-81. PMID 12505356 DOI: 10.1016/S0300-483X(02)00460-2  0.736
2002 Pawlak MR, Banik-Maiti S, Pietenpol JA, Ruley HE. Protein arginine methyltransferase I: substrate specificity and role in hnRNP assembly. Journal of Cellular Biochemistry. 87: 394-407. PMID 12397599 DOI: 10.1002/Jcb.10307  0.357
2002 Sniezek JC, Matheny KE, Burkey BB, Netterville JL, Pietenpol JA. Expression of p63 and 14-3-3sigma in normal and hyperdifferentiated mucosa of the upper aerodigestive tract. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 126: 598-601. PMID 12087324 DOI: 10.1067/Mhn.2002.125302  0.482
2002 Eichten A, Westfall M, Pietenpol JA, Münger K. Stabilization and functional impairment of the tumor suppressor p53 by the human papillomavirus type 16 E7 oncoprotein. Virology. 295: 74-85. PMID 12033767 DOI: 10.1006/Viro.2002.1375  0.816
2002 Chakravarthy A, Nicholson B, Kelley M, Beauchamp D, Johnson D, Frexes-Steed M, Simpson J, Shyr Y, Pietenpol J. A pilot study of neoadjuvant paclitaxel and radiation with correlative molecular studies in stage II/III breast cancer. Clinical Breast Cancer. 1: 68-71. PMID 11899393 DOI: 10.3816/Cbc.2000.N.007  0.3
2002 Coleman SC, Stewart ZA, Day TA, Netterville JL, Burkey BB, Pietenpol JA. Analysis of cell-cycle checkpoint pathways in head and neck cancer cell lines: implications for therapeutic strategies. Archives of Otolaryngology--Head & Neck Surgery. 128: 167-76. PMID 11843726 DOI: 10.1001/Archotol.128.2.167  0.692
2001 Ji C, Amarnath V, Pietenpol JA, Marnett LJ. 4-Hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release Chemical Research in Toxicology. 14: 1090-1096. PMID 11511183 DOI: 10.1021/Tx000186F  0.334
2001 Szak ST, Mays D, Pietenpol JA. Kinetics of p53 binding to promoter sites in vivo. Molecular and Cellular Biology. 21: 3375-86. PMID 11313463 DOI: 10.1128/Mcb.21.10.3375-3386.2001  0.826
2001 Stewart ZA, Pietenpol JA. p53 Signaling and cell cycle checkpoints. Chemical Research in Toxicology. 14: 243-63. PMID 11258974 DOI: 10.1021/Tx000199T  0.734
2001 Stewart ZA, Pietenpol JA. Syk: a new player in the field of breast cancer. Breast Cancer Research : Bcr. 3: 5-7. PMID 11250739 DOI: 10.1186/Bcr261  0.677
2001 Stewart ZA, Tang LJ, Pietenpol JA. Increased p53 phosphorylation after microtubule disruption is mediated in a microtubule inhibitor- and cell-specific manner. Oncogene. 20: 113-24. PMID 11244509 DOI: 10.1038/Sj.Onc.1204060  0.756
2000 Flatt PM, Pietenpol JA. Mechanisms of cell-cycle checkpoints: at the crossroads of carcinogenesis and drug discovery. Drug Metabolism Reviews. 32: 283-305. PMID 11139130 DOI: 10.1081/Dmr-100102335  0.781
2000 Song SY, Meszoely IM, Coffey RJ, Pietenpol JA, Leach SD. K-Ras-independent effects of the farnesyl transferase inhibitor L- 744,832 on cyclin B1/Cdc2 kinase activity, G2/M cell cycle progression and apoptosis in human pancreatic ductal adenocarcinoma cells Neoplasia. 2: 261-272. PMID 10935512 DOI: 10.1038/Sj.Neo.7900088  0.362
2000 Flatt PM, Polyak K, Tang LJ, Scatena CD, Westfall MD, Rubinstein LA, Yu J, Kinzler KW, Vogelstein B, Hill DE, Pietenpol JA. p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest. Cancer Letters. 156: 63-72. PMID 10840161 DOI: 10.1016/S0304-3835(00)00441-9  0.835
2000 Flatt PM, Tang LJ, Scatena CD, Szak ST, Pietenpol JA. p53 regulation of G(2) checkpoint is retinoblastoma protein dependent. Molecular and Cellular Biology. 20: 4210-23. PMID 10825186 DOI: 10.1128/Mcb.20.12.4210-4223.2000  0.822
1999 Stewart ZA, Pietenpol JA. Cell cycle checkpoints as therapeutic targets. Journal of Mammary Gland Biology and Neoplasia. 4: 389-400. PMID 10705922 DOI: 10.1023/A:1018770417964  0.702
1999 Stewart ZA, Mays D, Pietenpol JA. Defective G1-S cell cycle checkpoint function sensitizes cells to microtubule inhibitor-induced apoptosis. Cancer Research. 59: 3831-7. PMID 10447002  0.729
1999 Szak ST, Pietenpol JA. High affinity insertion/deletion lesion binding by p53. Evidence for a role of the p53 central domain. The Journal of Biological Chemistry. 274: 3904-9. PMID 9920946 DOI: 10.1074/Jbc.274.6.3904  0.782
1999 Stewart ZA, Leach SD, Pietenpol JA. p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption. Molecular and Cellular Biology. 19: 205-15. PMID 9858545 DOI: 10.1128/Mcb.19.1.205  0.764
1998 Scatena CD, Stewart ZA, Mays D, Tang LJ, Keefer CJ, Leach SD, Pietenpol JA. Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest. The Journal of Biological Chemistry. 273: 30777-84. PMID 9804855 DOI: 10.1074/Jbc.273.46.30777  0.676
1998 Leach SD, Scatena CD, Keefer CJ, Goodman HA, Song SY, Yang L, Pietenpol JA. Negative regulation of wee1 expression and Cdc2 phosphorylation during p53-mediated growth arrest and apoptosis Cancer Research. 58: 3231-3236. PMID 9699647  0.422
1998 Flatt PM, Price JO, Shaw A, Pietenpol JA. Differential cell cycle checkpoint response in normal human keratinocytes and fibroblasts. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 9: 535-43. PMID 9690621  0.757
1998 Ji C, Rouzer CA, Marnett LJ, Pietenpol JA. Induction of cell cycle arrest by the endogenous product of lipid peroxidation, malondialdehyde Carcinogenesis. 19: 1275-1283. PMID 9683189 DOI: 10.1093/Carcin/19.7.1275  0.497
1998 Jennings MT, Pietenpol JA. The role of transforming growth factor β in glioma progression Journal of Neuro-Oncology. 36: 123-140. PMID 9525812 DOI: 10.1023/A:1005863419880  0.349
1997 Ji C, Marnett LJ, Pietenpol JA. Cell cycle re-entry following chemically-induced cell cycle synchronization leads to elevated p53 and p21 protein levels Oncogene. 15: 2749-2753. PMID 9401002 DOI: 10.1038/Sj.Onc.1201441  0.527
1997 Coursen JD, Bennett WP, Khan MA, Forrester K, Pietenpol JA, Harris CC. Differential effects of p53 mutants on the growth of human bronchial epithelial cells. Molecular Carcinogenesis. 19: 191-203. PMID 9254886 DOI: 10.1002/(Sici)1098-2744(199707)19:3<191::Aid-Mc7>3.0.Co;2-H  0.404
1997 Koury MJ, Horne DW, Brown ZA, Pietenpol JA, Blount BC, Ames BN, Hard R, Koury ST. Apoptosis of late-stage erythroblasts in megaloblastic anemia: Association with DNA damage and macrocyte production Blood. 89: 4617-4623. PMID 9192787 DOI: 10.1182/Blood.V89.12.4617  0.315
1997 Ji C, Pietenpol JA, Marnett LJ. Bc12 prevents human cancer cells from 4hydroxynonenal induced apoptosis Faseb Journal. 11.  0.354
1996 Pietenpol JA, Lengauer C, Jordan J, Kinzler KW, Vogelstein B. Mammalian cells resistant to tumor suppressor genes Proceedings of the National Academy of Sciences of the United States of America. 93: 8390-8394. PMID 8710881 DOI: 10.1073/Pnas.93.16.8390  0.499
1995 Pietenpol JA, Bohlander SK, Sato Y, Papadopoulos N, Liu B, Friedman C, Trask BJ, Roberts JM, Kinzler KW, Rowley JD. Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias. Cancer Research. 55: 1206-10. PMID 7882309  0.425
1994 Pietenpol JA, Tokino T, Thiagalingam S, El-Deiry WS, Kinzler KW, Vogelstein B. Sequence-specific transcriptional activation is essential for growth suppression by p53 Proceedings of the National Academy of Sciences of the United States of America. 91: 1998-2002. PMID 8134338 DOI: 10.1073/Pnas.91.6.1998  0.5
1994 El-Deiry WS, O'Connor PM, Burrell M, Wang Y, Elledge SJ, Harper JW, Mercer WE, Velculescu VE, Jackman J, Hill DE, Wiman KG, Canman CE, Kohn KW, Pietenpol JA, Kastan MB, et al. WAF1/CIP1 Is Induced in p53-mediated G1 Arrest and Apoptosis Cancer Research. 54: 1169-1174. PMID 8118801  0.467
1994 Pietenpol JA, Markowitz S, Papadopoulos N, Willson JKV, Kinzler KW, Vogelstein B. Paradoxical Inhibition of Solid Tumor Cell Growth by bcl2 Cancer Research. 54: 3714-3717. PMID 8033089  0.303
1993 Oliner JD, Pietenpol JA, Thiagalingam S, Gyuris J, Kinzler KW, Vogelstein B. Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53 Nature. 362: 857-860. PMID 8479525 DOI: 10.1038/362857A0  0.492
1993 Pietenpol JA, Vogelstein B. No room at the p53 inn Nature. 365: 17-18. PMID 8361531 DOI: 10.1038/365017A0  0.47
1992 Kern SE, Pietenpol JA, Thiagalingam S, Seymour A, Kinzler KW, Vogelstein B. Oncogenic forms of p53 inhibit p53-regulated gene expression Science. 256: 827-830. PMID 1589764 DOI: 10.1126/Science.1589764  0.541
1992 El-Deiry WS, Kern SE, Pietenpol JA, Kinzler KW, Vogelstein B. Definition of a consensus binding site for p53 Nature Genetics. 1: 45-49. PMID 1301998 DOI: 10.1038/Ng0492-45  0.444
1991 Pietenpol JA, Münger K, Howley PM, Stein RW, Moses HL. Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product. Proceedings of the National Academy of Sciences of the United States of America. 88: 10227-31. PMID 1946442 DOI: 10.1073/Pnas.88.22.10227  0.314
1991 Murphy CS, Pietenpol JA, Munger K, Howley PM, Moses HL. c-myc and pRB: Role in TGF-β1 inhibition of keratinocyte proliferation Cold Spring Harbor Symposia On Quantitative Biology. 56: 129-135. PMID 1819482 DOI: 10.1101/Sqb.1991.056.01.017  0.322
1990 Pietenpol JA, Holt JT, Stein RW, Moses HL. Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation. Proceedings of the National Academy of Sciences of the United States of America. 87: 3758-62. PMID 2187192 DOI: 10.1073/Pnas.87.10.3758  0.304
1990 Pietenpol JA, Stein RW, Moran E, Yaciuk P, Schlegel R, Lyons RM, Pittelkow MR, Münger K, Howley PM, Moses HL. TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell. 61: 777-85. PMID 2140528 DOI: 10.1016/0092-8674(90)90188-K  0.313
1989 Pietenpol JA, Howe PH, Cunningham MR, Leof EB. Interferon α/β modulation of growth-factor-stimulated mitogenicity in AKR-2B fibroblasts Journal of Cellular Physiology. 141: 453-460. PMID 2687295 DOI: 10.1002/Jcp.1041410302  0.306
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