Douglas D. Richman - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Cell Biology, Microbiology Biology

374 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Beliakova-Bethell N, Mukim A, White CH, Deshmukh S, Abewe H, Richman DD, Spina CA. Histone deacetylase inhibitors induce complex host responses that contribute to differential potencies of these compounds in HIV reactivation. The Journal of Biological Chemistry. PMID 30745362 DOI: 10.1074/jbc.RA118.005185  0.32
2018 White CH, Beliakova-Bethell N, Lada SM, Breen MS, Hurst TP, Spina CA, Richman DD, Frater J, Magiorkinis G, Woelk CH. Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment. Frontiers in Immunology. 9: 603. PMID 29706951 DOI: 10.3389/fimmu.2018.00603  0.32
2017 Chaillon A, Gianella S, Lada SM, Perez-Santiago J, Jordan P, Ignacio C, Karris M, Richman D, Mehta SR, Little SJ, Wertheim JO, Smith DM. Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc. Journal of Virology. PMID 29142136 DOI: 10.1128/JVI.01589-17  0.36
2017 Wagner GA, Landais E, Caballero G, Phung P, Kosakovsky Pond SL, Poignard P, Richman DD, Little SJ, Smith DM. Intrasubtype B HIV-1 Superinfection Correlates with Delayed Neutralizing Antibody Response. Journal of Virology. PMID 28615205 DOI: 10.1128/JVI.00475-17  0.36
2017 Beliakova-Bethell N, Hezareh M, Wong JK, Strain MC, Lewinski MK, Richman DD, Spina CA. Relative efficacy of T cell stimuli as inducers of productive HIV-1 replication in latently infected CD4 lymphocytes from patients on suppressive cART. Virology. 508: 127-133. PMID 28527342 DOI: 10.1016/j.virol.2017.05.008  0.32
2017 Choi JY, Pond SLK, Anderson CM, Richman DD, Smith DM. Molecular Features of the V1-V4 Coding Region of Sexually Transmitted HIV-1. The Journal of Infectious Diseases. PMID 28419276 DOI: 10.1093/infdis/jix184  0.36
2017 Vesa J, Chaillon A, Wagner GA, Anderson CM, Richman DD, Smith DM, Little SJ. Increased HIV-1 superinfection risk in carriers of specific human leukocyte antigen alleles. Aids (London, England). PMID 28244954 DOI: 10.1097/QAD.0000000000001445  0.36
2016 Chaillon A, Gianella S, Little SJ, Caballero G, Barin F, Kosakovsky Pond S, Richman DD, Smith DM, Mehta SR. Characterizing the multiplicity of HIV founder variants during sexual transmission among MSM. Virus Evolution. 2: vew012. PMID 30186625 DOI: 10.1093/ve/vew012  0.36
2016 Laird Smith M, Murrell B, Eren K, Ignacio C, Landais E, Weaver S, Phung P, Ludka C, Hepler L, Caballero G, Pollner T, Guo Y, Richman D, Poignard P, et al. Rapid Sequencing of CompleteGenes from Primary HIV-1 Samples. Virus Evolution. 2: vew018. PMID 29492273 DOI: 10.1093/ve/vew018  0.36
2016 White CH, Moesker B, Beliakova-Bethell N, Martins LJ, Spina CA, Margolis DM, Richman DD, Planelles V, Bosque A, Woelk CH. Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model. Plos Pathogens. 12: e1006026. PMID 27898737 DOI: 10.1371/journal.ppat.1006026  0.32
2016 Karris MY, Umlauf A, Vaida F, Richman D, Little S, Smith D. A randomized controlled clinical trial on the impact of CCR5 blockade with maraviroc in early infection on T-cell dynamics. Medicine. 95: e5315. PMID 27858912 DOI: 10.1097/MD.0000000000005315  0.32
2016 Wagner GA, Chaillon A, Liu S, Franklin DR, Caballero G, Kosakovsky Pond SL, Vaida F, Heaton RK, Letendre SL, Grant I, Richman DD, Smith DM. HIV-associated neurocognitive disorder is associated with HIV-1 dual infection. Aids (London, England). PMID 27536983 DOI: 10.1097/QAD.0000000000001237  0.36
2016 Mehta SR, Murrell B, Anderson CM, Kosakovsky Pond SL, Wertheim JO, Young JA, Freitas L, Richman DD, Mathews WC, Scheffler K, Little SJ, Smith DM. Using HIV Sequence and Epidemiologic Data to Assess the Effect of Self-referral Testing for Acute HIV Infection on Incident Diagnoses in San Diego, California. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 27174704 DOI: 10.1093/cid/ciw161  0.36
2016 Richman DD. HIV is putting up less resistance. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 26962077 DOI: 10.1093/cid/ciw130  0.36
2016 Panichsillapakit T, Patel D, Santangelo J, Richman DD, Little SJ, Smith DM. Colorectal Disorders in Acute Human Immunodeficiency Virus Infection: A Case Series. Open Forum Infectious Diseases. 3: ofw014. PMID 26925432 DOI: 10.1093/ofid/ofw014  0.36
2016 Gianella S, Anderson C, Var SR, Oliveira MF, Lada S, Vargas M, Massanella M, Little S, Richman D, Strain M, Pérez-Santiago J, Smith D. Replication of Human Herpes Viruses is Associated with Greater HIV DNA Levels during Antiretroviral Therapy Started during Early HIV Infection. Journal of Virology. PMID 26842469 DOI: 10.1128/JVI.02638-15  0.36
2016 Massanella M, Richman DD. Measuring the latent reservoir in vivo. The Journal of Clinical Investigation. 126: 464-72. PMID 26829625 DOI: 10.1172/JCI80567  0.36
2015 Richman DD. HIV: Cure by killing. Nature. 528: 198-9. PMID 26633623 DOI: 10.1038/nature16321  0.36
2015 Gianella S, Anderson CM, Richman DD, Smith DM, Little SJ. No evidence of posttreatment control after early initiation of antiretroviral therapy. Aids (London, England). 29: 2093-7. PMID 26544575 DOI: 10.1097/QAD.0000000000000816  0.36
2015 Panichsillapakit T, Smith DM, Wertheim JO, Richman DD, Little SJ, Mehta SR. Prevalence of transmitted HIV drug resistance among recently infected persons in San Diego, California 1996-2013. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 26413846 DOI: 10.1097/QAI.0000000000000831  0.36
2015 White CH, Johnston HE, Moesker B, Manousopoulou A, Margolis DM, Richman DD, Spina CA, Garbis SD, Woelk CH, Beliakova-Bethell N. Mixed effects of suberoylanilide hydroxamic acid (SAHA) on the host transcriptome and proteome and their implications for HIV reactivation from latency. Antiviral Research. 123: 78-85. PMID 26343910 DOI: 10.1016/j.antiviral.2015.09.002  0.32
2015 Massanella M, Gianella S, Schrier R, Dan JM, Pérez-Santiago J, Oliveira MF, Richman DD, Little SJ, Benson CA, Daar ES, Dube MP, Haubrich RH, Smith DM, Morris SR. Methamphetamine Use in HIV-infected Individuals Affects T-cell Function and Viral Outcome during Suppressive Antiretroviral Therapy. Scientific Reports. 5: 13179. PMID 26299251 DOI: 10.1038/srep13179  0.36
2015 Abdel-Mohsen M, Wang C, Strain MC, Lada SM, Deng X, Cockerham LR, Pilcher CD, Hecht FM, Liegler T, Richman DD, Deeks SG, Pillai SK. Select host restriction factors are associated with HIV persistence during antiretroviral therapy. Aids (London, England). 29: 411-20. PMID 25602681 DOI: 10.1097/QAD.0000000000000572  0.36
2015 Carter CC, Wagner GA, Hightower GK, Caballero G, Phung P, Richman DD, Pond SL, Smith DM. HIV-1 neutralizing antibody response and viral genetic diversity characterized with next generation sequencing. Virology. 474: 34-40. PMID 25463602 DOI: 10.1016/j.virol.2014.10.019  0.36
2015 Okulicz JF, Le TD, Agan BK, Camargo JF, Landrum ML, Wright E, Dolan MJ, Ganesan A, Ferguson TM, Smith DM, Richman DD, Little SJ, Clark RA, He W, Ahuja SK. Influence of the timing of antiretroviral therapy on the potential for normalization of immune status in human immunodeficiency virus 1-infected individuals. Jama Internal Medicine. 175: 88-99. PMID 25419650 DOI: 10.1001/jamainternmed.2014.4010  0.36
2015 Procopio FA, Fromentin R, Kulpa DA, Brehm JH, Bebin AG, Strain MC, Richman DD, O'Doherty U, Palmer S, Hecht FM, Hoh R, Barnard RJO, Miller MD, Hazuda DJ, Deeks SG, et al. A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals Ebiomedicine. DOI: 10.1016/j.ebiom.2015.06.019  0.36
2014 Massanella M, Ouchi D, Marfil S, Llibre JM, Puertas MC, Buzón MJ, Richman DD, Orna E, Stevenson M, Gatell JM, Domingo P, Negredo E, Martinez-Picado J, Clotet B, Blanco J. Different plasma markers of inflammation are influenced by immune recovery and cART composition or intensification in treated HIV infected individuals. Plos One. 9: e114142. PMID 25462535 DOI: 10.1371/journal.pone.0114142  0.36
2014 Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG. CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells. Plos One. 9: e110731. PMID 25340755 DOI: 10.1371/journal.pone.0110731  0.36
2014 Persaud D, Patel K, Karalius B, Rainwater-Lovett K, Ziemniak C, Ellis A, Chen YH, Richman D, Siberry GK, Van Dyke RB, Burchett S, Seage GR, Luzuriaga K. Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescents. Jama Pediatrics. 168: 1138-46. PMID 25286283 DOI: 10.1001/jamapediatrics.2014.1560  0.36
2014 Hepler NL, Scheffler K, Weaver S, Murrell B, Richman DD, Burton DR, Poignard P, Smith DM, Kosakovsky Pond SL. IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform. Plos Computational Biology. 10: e1003842. PMID 25254639 DOI: 10.1371/journal.pcbi.1003842  0.36
2014 Menéndez-Arias L, Richman DD. Editorial overview: antivirals and resistance: advances and challenges ahead. Current Opinion in Virology. 8: iv-vii. PMID 25155454 DOI: 10.1016/j.coviro.2014.08.002  0.36
2014 Kim EY, Lorenzo-Redondo R, Little SJ, Chung YS, Phalora PK, Maljkovic Berry I, Archer J, Penugonda S, Fischer W, Richman DD, Bhattacharya T, Malim MH, Wolinsky SM. Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection. Plos Pathogens. 10: e1004281. PMID 25080100 DOI: 10.1371/journal.ppat.1004281  0.36
2014 Wang C, Abdel-Mohsen M, Strain MC, Lada SM, Yukl S, Cockerham LR, Pilcher CD, Hecht FM, Sinclair E, Liegler T, Richman DD, Deeks SG, Pillai SK. Decreased HIV type 1 transcription in CCR5-Δ32 heterozygotes during suppressive antiretroviral therapy. The Journal of Infectious Diseases. 210: 1838-43. PMID 24935955 DOI: 10.1093/infdis/jiu338  0.36
2014 Luzuriaga K, Tabak B, Garber M, Chen YH, Ziemniak C, McManus MM, Murray D, Strain MC, Richman DD, Chun TW, Cunningham CK, Persaud D. HIV type 1 (HIV-1) proviral reservoirs decay continuously under sustained virologic control in HIV-1-infected children who received early treatment. The Journal of Infectious Diseases. 210: 1529-38. PMID 24850788 DOI: 10.1093/infdis/jiu297  0.36
2014 Gianella S, Massanella M, Richman DD, Little SJ, Spina CA, Vargas MV, Lada SM, Daar ES, Dube MP, Haubrich RH, Morris SR, Smith DM. Cytomegalovirus replication in semen is associated with higher levels of proviral HIV DNA and CD4+ T cell activation during antiretroviral treatment. Journal of Virology. 88: 7818-27. PMID 24789781 DOI: 10.1128/JVI.00831-14  0.36
2014 Archin NM, Bateson R, Tripathy MK, Crooks AM, Yang KH, Dahl NP, Kearney MF, Anderson EM, Coffin JM, Strain MC, Richman DD, Robertson KR, Kashuba AD, Bosch RJ, Hazuda DJ, et al. HIV-1 expression within resting CD4+ T cells after multiple doses of vorinostat. The Journal of Infectious Diseases. 210: 728-35. PMID 24620025 DOI: 10.1093/infdis/jiu155  0.36
2014 Richman DD. Editorial Commentary: Extending HIV drug resistance testing to low levels of plasma viremia. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 58: 1174-5. PMID 24429434 DOI: 10.1093/cid/ciu025  0.36
2014 Chaillon A, Gianella S, Massanella Luna M, Little SJ, Richman DD, Mehta SR. A case cluster demonstrating the relationship between HLA concordance and virologic and disease outcomes in human immunodeficiency virus infection. Virology. 449: 104-8. PMID 24418543 DOI: 10.1016/j.virol.2013.11.012  0.36
2014 Tilghman MW, Pérez-Santiago J, Osorio G, Little SJ, Richman DD, Mathews WC, Haubrich RH, Smith DM. Community HIV-1 drug resistance is associated with transmitted drug resistance. Hiv Medicine. 15: 339-46. PMID 24417811 DOI: 10.1111/hiv.12122  0.36
2014 Karris MY, Kao YT, Patel D, Dawson M, Woods SP, Vaida F, Spina C, Richman D, Little S, Smith DM. Predictors of virologic response in persons who start antiretroviral therapy during recent HIV infection. Aids (London, England). 28: 841-9. PMID 24401640 DOI: 10.1097/QAD.0000000000000149  0.36
2014 Chaillon A, Gianella S, Wertheim JO, Richman DD, Mehta SR, Smith DM. HIV migration between blood and cerebrospinal fluid or semen over time. The Journal of Infectious Diseases. 209: 1642-52. PMID 24302756 DOI: 10.1093/infdis/jit678  0.36
2014 Wagner GA, Pacold ME, Kosakovsky Pond SL, Caballero G, Chaillon A, Rudolph AE, Morris SR, Little SJ, Richman DD, Smith DM. Incidence and prevalence of intrasubtype HIV-1 dual infection in at-risk men in the United States. The Journal of Infectious Diseases. 209: 1032-8. PMID 24273040 DOI: 10.1093/infdis/jit633  0.36
2014 Tatro ET, Purnajo I, Richman DD, Smith DM, Gianella S. Antibody response to Achromobacter xylosoxidans during HIV infection is associated with lower CD4 levels and increased lymphocyte activation. Clinical and Vaccine Immunology : Cvi. 21: 46-50. PMID 24173027 DOI: 10.1128/CVI.00553-13  0.36
2014 Wertheim JO, Leigh Brown AJ, Hepler NL, Mehta SR, Richman DD, Smith DM, Kosakovsky Pond SL. The global transmission network of HIV-1. The Journal of Infectious Diseases. 209: 304-13. PMID 24151309 DOI: 10.1093/infdis/jit524  0.36
2014 Chaillon A, Gianella S, Vazquez H, Ignacio C, Zweig AC, Richman DD, Smith DM. Novel codon insert in HIV type 1 clade B reverse transcriptase associated with low-level viremia during antiretroviral therapy. Aids Research and Human Retroviruses. 30: 165-9. PMID 24020934 DOI: 10.1089/AID.2013.0202  0.36
2014 Gianella S, Morris SR, Tatro E, Vargas MV, Haubrich RH, Daar ES, Dube MP, Richman DD, Little SJ, Smith DM. Virologic correlates of anti-CMV IgG levels in HIV-1-infected men. The Journal of Infectious Diseases. 209: 452-6. PMID 23964106 DOI: 10.1093/infdis/jit434  0.36
2013 Pérez-Santiago J, Gianella S, Massanella M, Spina CA, Karris MY, Var SR, Patel D, Jordan PS, Young JA, Little SJ, Richman DD, Smith DM. Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection. Aids (London, England). 27: 1921-31. PMID 24180001 DOI: 10.1097/QAD.0b013e3283611816  0.36
2013 Chaillon A, Wagner GA, Hepler NL, Little SJ, Kosakovsky Pond SL, Caballero G, Pacold ME, Phung P, Wrin T, Richman DD, Wertheim JO, Smith DM. Dynamics of viral evolution and neutralizing antibody response after HIV-1 superinfection. Journal of Virology. 87: 12737-44. PMID 24049166 DOI: 10.1128/JVI.02260-13  0.36
2013 Hatano H, Strain MC, Scherzer R, Bacchetti P, Wentworth D, Hoh R, Martin JN, McCune JM, Neaton JD, Tracy RP, Hsue PY, Richman DD, Deeks SG. Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: a randomized, placebo-controlled trial. The Journal of Infectious Diseases. 208: 1436-42. PMID 23975885 DOI: 10.1093/infdis/jit453  0.36
2013 Massanella M, Singhania A, Beliakova-Bethell N, Pier R, Lada SM, White CH, Pérez-Santiago J, Blanco J, Richman DD, Little SJ, Woelk CH. Differential gene expression in HIV-infected individuals following ART. Antiviral Research. 100: 420-8. PMID 23933117 DOI: 10.1016/j.antiviral.2013.07.017  0.36
2013 Hightower GK, May SJ, Pérez-Santiago J, Pacold ME, Wagner GA, Little SJ, Richman DD, Mehta SR, Smith DM, Pond SL. HIV-1 clade B pol evolution following primary infection. Plos One. 8: e68188. PMID 23840830 DOI: 10.1371/journal.pone.0068188  0.36
2013 Wagner GA, Pacold ME, Vigil E, Caballero G, Morris SR, Kosakovsky Pond SL, Little SJ, Richman DD, Gianella S, Smith DM. Using ultradeep pyrosequencing to study HIV-1 coreceptor usage in primary and dual infection. The Journal of Infectious Diseases. 208: 271-4. PMID 23599311 DOI: 10.1093/infdis/jit168  0.36
2013 Gianella S, Smith DM, Vargas MV, Little SJ, Richman DD, Daar ES, Dube MP, Zhang F, Ginocchio CC, Haubrich RH, Morris SR. Shedding of HIV and human herpesviruses in the semen of effectively treated HIV-1-infected men who have sex with men. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 57: 441-7. PMID 23595831 DOI: 10.1093/cid/cit252  0.36
2013 Strain MC, Lada SM, Luong T, Rought SE, Gianella S, Terry VH, Spina CA, Woelk CH, Richman DD. Highly precise measurement of HIV DNA by droplet digital PCR. Plos One. 8: e55943. PMID 23573183 DOI: 10.1371/journal.pone.0055943  0.36
2013 Katlama C, Deeks SG, Autran B, Martinez-Picado J, van Lunzen J, Rouzioux C, Miller M, Vella S, Schmitz JE, Ahlers J, Richman DD, Sekaly RP. Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs. Lancet. 381: 2109-17. PMID 23541541 DOI: 10.1016/S0140-6736(13)60104-X  0.36
2013 Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, Bosch RJ, Lai J, Chioma S, Emad F, Abdel-Mohsen M, Hoh R, Hecht F, Hunt P, Somsouk M, ... ... Richman DD, et al. Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. Plos Pathogens. 9: e1003174. PMID 23459007 DOI: 10.1371/journal.ppat.1003174  0.36
2013 Le T, Wright EJ, Smith DM, He W, Catano G, Okulicz JF, Young JA, Clark RA, Richman DD, Little SJ, Ahuja SK. Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy. The New England Journal of Medicine. 368: 218-30. PMID 23323898 DOI: 10.1056/NEJMoa1110187  0.36
2013 Strain MC, Richman DD. New assays for monitoring residual HIV burden in effectively treated individuals. Current Opinion in Hiv and Aids. 8: 106-10. PMID 23314907 DOI: 10.1097/COH.0b013e32835d811b  0.36
2013 Wie SH, Du P, Luong TQ, Rought SE, Beliakova-Bethell N, Lozach J, Corbeil J, Kornbluth RS, Richman DD, Woelk CH. HIV downregulates interferon-stimulated genes in primary macrophages. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 33: 90-5. PMID 23276142 DOI: 10.1089/jir.2012.0052  0.36
2013 Gianella S, Anderson CM, Vargas MV, Richman DD, Little SJ, Morris SR, Smith DM. Cytomegalovirus DNA in semen and blood is associated with higher levels of proviral HIV DNA. The Journal of Infectious Diseases. 207: 898-902. PMID 23275608 DOI: 10.1093/infdis/jis777  0.36
2013 Beliakova-Bethell N, Zhang JX, Singhania A, Lee V, Terry VH, Richman DD, Spina CA, Woelk CH. Suberoylanilide hydroxamic acid induces limited changes in the transcriptome of primary CD4(+) T cells. Aids (London, England). 27: 29-37. PMID 23221426 DOI: 10.1097/QAD.0b013e32835b3e26  0.36
2013 Gianella S, Morris SR, Vargas MV, Young JA, Callahan B, Richman DD, Little SJ, Smith DM. Role of seminal shedding of herpesviruses in HIV Type 1 Transmission. The Journal of Infectious Diseases. 207: 257-61. PMID 23148284 DOI: 10.1093/infdis/jis683  0.36
2013 Stadeli KM, Richman DD. Rates of emergence of HIV drug resistance in resource-limited settings: a systematic review. Antiviral Therapy. 18: 115-23. PMID 23052978 DOI: 10.3851/IMP2437  0.36
2013 Soto PC, Karris MY, Spina CA, Richman DD, Varki A. Cell-intrinsic mechanism involving Siglec-5 associated with divergent outcomes of HIV-1 infection in human and chimpanzee CD4 T cells. Journal of Molecular Medicine (Berlin, Germany). 91: 261-70. PMID 22945238 DOI: 10.1007/s00109-012-0951-7  0.36
2013 Gianella S, Morris SR, Anderson C, Spina CA, Vargas MV, Young JA, Richman DD, Little SJ, Smith DM. Herpes viruses and HIV-1 drug resistance mutations influence the virologic and immunologic milieu of the male genital tract. Aids (London, England). 27: 39-47. PMID 22739399 DOI: 10.1097/QAD.0b013e3283573305  0.36
2012 Gianella S, Mehta SR, Young JA, Vargas MV, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM. Sexual transmission of predicted CXCR4-tropic HIV-1 likely originating from the source partner's seminal cells. Virology. 434: 2-4. PMID 23040890 DOI: 10.1016/j.virol.2012.09.010  0.36
2012 Hightower GK, Wong JK, Letendre SL, Umlauf AA, Ellis RJ, Ignacio CC, Heaton RK, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, ... ... Richman DD, et al. Higher HIV-1 genetic diversity is associated with AIDS and neuropsychological impairment. Virology. 433: 498-505. PMID 22999095 DOI: 10.1016/j.virol.2012.08.028  0.36
2012 Gianella S, Mehta SR, Strain MC, Young JA, Vargas MV, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM. Impact of seminal cytomegalovirus replication on HIV-1 dynamics between blood and semen. Journal of Medical Virology. 84: 1703-9. PMID 22997072 DOI: 10.1002/jmv.23398  0.36
2012 Richman DD. Antiretroviral drug resistance in resource-limited settings. Lancet (London, England). 380: 1210-1. PMID 22828483 DOI: 10.1016/S0140-6736(12)61188-X  0.36
2012 Thompson MA, Aberg JA, Hoy JF, Telenti A, Benson C, Cahn P, Eron JJ, Günthard HF, Hammer SM, Reiss P, Richman DD, Rizzardini G, Thomas DL, Jacobsen DM, Volberding PA. Antiretroviral treatment of adult HIV infection: 2012 recommendations of the International Antiviral Society-USA panel. Jama. 308: 387-402. PMID 22820792 DOI: 10.1001/jama.2012.7961  0.36
2012 Tilghman MW, May S, Pérez-Santiago J, Ignacio CC, Little SJ, Richman DD, Smith DM. A combined screening platform for HIV treatment failure and resistance. Plos One. 7: e35401. PMID 22563383 DOI: 10.1371/journal.pone.0035401  0.36
2012 Choi JY, Hightower GK, Wong JK, Heaton R, Woods S, Grant I, Marcotte TD, Ellis RJ, Letendre SL, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, ... ... Richman DD, et al. Genetic features of cerebrospinal fluid-derived subtype B HIV-1 tat. Journal of Neurovirology. 18: 81-90. PMID 22528397 DOI: 10.1007/s13365-011-0059-9  0.36
2012 Mehta SR, Kosakovsky Pond SL, Young JA, Richman D, Little S, Smith DM. Associations between phylogenetic clustering and HLA profile among HIV-infected individuals in San Diego, California. The Journal of Infectious Diseases. 205: 1529-33. PMID 22448013 DOI: 10.1093/infdis/jis231  0.36
2012 Agrawal A, DeSoto J, Fullagar JL, Maddali K, Rostami S, Richman DD, Pommier Y, Cohen SM. Probing chelation motifs in HIV integrase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 109: 2251-6. PMID 22308350 DOI: 10.1073/pnas.1112389109  0.36
2012 Gianella S, Strain MC, Rought SE, Vargas MV, Little SJ, Richman DD, Spina CA, Smith DM. Associations between virologic and immunologic dynamics in blood and in the male genital tract. Journal of Virology. 86: 1307-15. PMID 22114342 DOI: 10.1128/JVI.06077-11  0.36
2012 Pacold ME, Pond SL, Wagner GA, Delport W, Bourque DL, Richman DD, Little SJ, Smith DM. Clinical, virologic, and immunologic correlates of HIV-1 intraclade B dual infection among men who have sex with men. Aids (London, England). 26: 157-65. PMID 22045341 DOI: 10.1097/QAD.0b013e32834dcd26  0.36
2012 Richman DD. Contending with the challenges of HIV: A first-hand account Future Virology. 7: 645-648. DOI: 10.2217/fvl.12.50  0.36
2011 Jeong J, Kim SR, Lee SH, Lim JH, Choi JI, Park JS, Chang CL, Choi JY, Richman DD, Smith DM. The Use of High Performance Liquid Chromatography to Speciate and Characterize the Epidemiology of Mycobacteria. Laboratory Medicine. 42: 612-617. PMID 24443588 DOI: 10.1309/LMDDEHPSYE6ZDM3C  0.36
2011 Magee WC, Valiaeva N, Beadle JR, Richman DD, Hostetler KY, Evans DH. Inhibition of HIV-1 by octadecyloxyethyl esters of (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] nucleosides and evaluation of their mechanism of action. Antimicrobial Agents and Chemotherapy. 55: 5063-72. PMID 21896914 DOI: 10.1128/AAC.05161-11  0.36
2011 Gianella S, Delport W, Pacold ME, Young JA, Choi JY, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM. Detection of minority resistance during early HIV-1 infection: natural variation and spurious detection rather than transmission and evolution of multiple viral variants. Journal of Virology. 85: 8359-67. PMID 21632754 DOI: 10.1128/JVI.02582-10  0.36
2011 Mascolini M, Mellors JW, Richman DD, Boucher CA, Larder BA. HIV and hepatitis virus resistance to antivirals: review of data from the XIX International HIV and Hepatitis Virus Drug Resistance Workshop and curative strategies. Antiviral Therapy. 16: 263-86. PMID 21447877 DOI: 10.3851/IMP1761  0.36
2011 Richman DD. Introduction: challenges to finding a cure for HIV infection. Current Opinion in Hiv and Aids. 6: 1-3. PMID 21242886 DOI: 10.1097/COH.0b013e328340ffa6  0.36
2011 Tilghman MW, Guerena DD, Licea A, Pérez-Santiago J, Richman DD, May S, Smith DM. Pooled nucleic acid testing to detect antiretroviral treatment failure in Mexico. Journal of Acquired Immune Deficiency Syndromes (1999). 56: e70-4. PMID 21124228 DOI: 10.1097/QAI.0b013e3181ff63d7  0.36
2010 Pacold M, Smith D, Little S, Cheng PM, Jordan P, Ignacio C, Richman D, Pond SK. Comparison of methods to detect HIV dual infection. Aids Research and Human Retroviruses. 26: 1291-8. PMID 20954840 DOI: 10.1089/aid.2010.0042  0.36
2010 Gianella S, Richman DD. Minority variants of drug-resistant HIV. The Journal of Infectious Diseases. 202: 657-66. PMID 20649427 DOI: 10.1086/655397  0.36
2010 Morris SR, Little SJ, Cunningham T, Garfein RS, Richman DD, Smith DM. Evaluation of an HIV nucleic acid testing program with automated Internet and voicemail systems to deliver results. Annals of Internal Medicine. 152: 778-85. PMID 20547906 DOI: 10.7326/0003-4819-152-12-201006150-00005  0.36
2010 Manosuthi W, Butler DM, Chantratita W, Sukasem C, Richman DD, Smith DM. Patients infected with HIV type 1 subtype CRF01_AE and failing first-line nevirapine- and efavirenz-based regimens demonstrate considerable cross-resistance to etravirine. Aids Research and Human Retroviruses. 26: 609-11. PMID 20507208 DOI: 10.1089/aid.2009.0107  0.36
2010 Butler DM, Delport W, Kosakovsky Pond SL, Lakdawala MK, Cheng PM, Little SJ, Richman DD, Smith DM. The origins of sexually transmitted HIV among men who have sex with men. Science Translational Medicine. 2: 18re1. PMID 20371483 DOI: 10.1126/scitranslmed.3000447  0.36
2010 Manosuthi W, Butler DM, Pérez-Santiago J, Poon AF, Pillai SK, Mehta SR, Pacold ME, Richman DD, Pond SK, Smith DM. Protease polymorphisms in HIV-1 subtype CRF01_AE represent selection by antiretroviral therapy and host immune pressure. Aids (London, England). 24: 411-6. PMID 20009919 DOI: 10.1097/QAD.0b013e3283350eef  0.36
2010 Poon AF, Swenson LC, Dong WW, Deng W, Kosakovsky Pond SL, Brumme ZL, Mullins JI, Richman DD, Harrigan PR, Frost SD. Phylogenetic analysis of population-based and deep sequencing data to identify coevolving sites in the nef gene of HIV-1. Molecular Biology and Evolution. 27: 819-32. PMID 19955476 DOI: 10.1093/molbev/msp289  0.36
2010 Woelk CH, Beliakova-Bethell N, Goicoechea M, Zhao Y, Du P, Rought SE, Lozach J, Pérez-Santiago J, Richman DD, Smith DM, Little SJ. Gene expression before HAART initiation predicts HIV-infected individuals at risk of poor CD4+ T-cell recovery. Aids (London, England). 24: 217-22. PMID 19952713 DOI: 10.1097/QAD.0b013e328334f1f0  0.36
2009 Mascolini M, Boucher CA, Mellors JW, Larder BA, Richman DD. Progress in basic and clinical research on HIV resistance: report on the XVIII International HIV Drug Resistance Workshop. Antiviral Therapy. 14: 1015-37. PMID 19918107 DOI: 10.3851/IMP1423  0.36
2009 Montaner JS, Richman DD, Hammer SM. Poor agreement between 2 assays for measuring low levels of HIV-1 viral load. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 49: 1283-4. PMID 19780662 DOI: 10.1086/605688  0.36
2009 Hightower GK, Letendre SL, Cherner M, Gibson SA, Ellis RJ, Wolfson TJ, Gamst AC, Ignacio CC, Heaton RK, Grant I, Richman DD, Smith DM. Select resistance-associated mutations in blood are associated with lower CSF viral loads and better neuropsychological performance. Virology. 394: 243-8. PMID 19762060 DOI: 10.1016/j.virol.2009.08.007  0.36
2009 Smith DM, May SJ, Pérez-Santiago J, Strain MC, Ignacio CC, Haubrich RH, Richman DD, Benson CA, Little SJ. The use of pooled viral load testing to identify antiretroviral treatment failure. Aids (London, England). 23: 2151-8. PMID 19730348 DOI: 10.1097/QAD.0b013e3283313ca9  0.36
2009 Butler DM, Pacold ME, Jordan PS, Richman DD, Smith DM. The efficiency of single genome amplification and sequencing is improved by quantitation and use of a bioinformatics tool. Journal of Virological Methods. 162: 280-3. PMID 19698751 DOI: 10.1016/j.jviromet.2009.08.002  0.36
2009 Jordan PS, Poon A, Eron J, Squires K, Ignacio C, Richman DD, Smith DM. A novel codon insert in protease of clade B HIV type 1. Aids Research and Human Retroviruses. 25: 547-50. PMID 19397401 DOI: 10.1089/aid.2008.0310  0.36
2009 Richman DD, Margolis DM, Delaney M, Greene WC, Hazuda D, Pomerantz RJ. The challenge of finding a cure for HIV infection. Science (New York, N.Y.). 323: 1304-7. PMID 19265012 DOI: 10.1126/science.1165706  0.36
2009 Nugent CT, Nodelman V, Giachetti C, Richman DD, Looney DJ. Evaluation of a highly sensitive qualitative human immunodeficiency virus type 1 (HIV-1) RNA assay for detection of HIV-1 suppression. Journal of Clinical Microbiology. 47: 833-6. PMID 19116355 DOI: 10.1128/JCM.01464-08  0.36
2009 Smith DM, Zárate S, Shao H, Pillai SK, Letendre SL, Wong JK, Richman DD, Frost SD, Ellis RJ. Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations. Virology. 385: 204-8. PMID 19100592 DOI: 10.1016/j.virol.2008.11.010  0.36
2009 Smith DM, May SJ, Tweeten S, Drumright L, Pacold ME, Kosakovsky Pond SL, Pesano RL, Lie YS, Richman DD, Frost SD, Woelk CH, Little SJ. A public health model for the molecular surveillance of HIV transmission in San Diego, California. Aids (London, England). 23: 225-32. PMID 19098493 DOI: 10.1097/QAD.0b013e32831d2a81  0.36
2008 Frost SD, Trkola A, Günthard HF, Richman DD. Antibody responses in primary HIV-1 infection. Current Opinion in Hiv and Aids. 3: 45-51. PMID 19372943 DOI: 10.1097/COH.0b013e3282f310ae  0.36
2008 Mascolini M, Larder BA, Boucher CA, Richman DD, Mellors JW. Broad advances in understanding HIV resistance to antiretrovirals: report on the XVII International HIV Drug Resistance Workshop. Antiviral Therapy. 13: 1097-113. PMID 19195337  0.36
2008 Hammer SM, Eron JJ, Reiss P, Schooley RT, Thompson MA, Walmsley S, Cahn P, Fischl MA, Gatell JM, Hirsch MS, Jacobsen DM, Montaner JS, Richman DD, Yeni PG, Volberding PA, et al. Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel. Jama. 300: 555-70. PMID 18677028 DOI: 10.1001/jama.300.5.555  0.36
2008 Butler DM, Smith DM, Cachay ER, Hightower GK, Nugent CT, Richman DD, Little SJ. Herpes simplex virus 2 serostatus and viral loads of HIV-1 in blood and semen as risk factors for HIV transmission among men who have sex with men. Aids (London, England). 22: 1667-71. PMID 18670228 DOI: 10.1097/QAD.0b013e32830bfed8  0.36
2008 Grant RM, Hamer D, Hope T, Johnston R, Lange J, Lederman MM, Lieberman J, Miller CJ, Moore JP, Mosier DE, Richman DD, Schooley RT, Springer MS, Veazey RS, Wainberg MA. Whither or wither microbicides? Science (New York, N.Y.). 321: 532-4. PMID 18653884 DOI: 10.1126/science.1160355  0.36
2008 Nelson JD, Kinkead H, Brunel FM, Leaman D, Jensen R, Louis JM, Maruyama T, Bewley CA, Bowdish K, Clore GM, Dawson PE, Frederickson S, Mage RG, Richman DD, Burton DR, et al. Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics. Virology. 377: 170-83. PMID 18499210 DOI: 10.1016/j.virol.2008.04.005  0.36
2008 Liu L, May S, Richman DD, Hecht FM, Markowitz M, Daar ES, Routy JP, Margolick JB, Collier AC, Woelk CH, Little SJ, Smith DM. Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance. Aids (London, England). 22: 835-9. PMID 18427201 DOI: 10.1097/QAD.0b013e3282f5ff71  0.36
2008 Kosakovsky Pond SL, Poon AF, Zárate S, Smith DM, Little SJ, Pillai SK, Ellis RJ, Wong JK, Leigh Brown AJ, Richman DD, Frost SD. Estimating selection pressures on HIV-1 using phylogenetic likelihood models. Statistics in Medicine. 27: 4779-89. PMID 18381707 DOI: 10.1002/sim.3192  0.36
2008 Ahuja SK, Kulkarni H, Catano G, Agan BK, Camargo JF, He W, O'Connell RJ, Marconi VC, Delmar J, Eron J, Clark RA, Frost S, Martin J, Ahuja SS, Deeks SG, ... ... Richman D, et al. CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals. Nature Medicine. 14: 413-20. PMID 18376407 DOI: 10.1038/nm1741  0.36
2008 Little SJ, Frost SD, Wong JK, Smith DM, Pond SL, Ignacio CC, Parkin NT, Petropoulos CJ, Richman DD. Persistence of transmitted drug resistance among subjects with primary human immunodeficiency virus infection. Journal of Virology. 82: 5510-8. PMID 18353964 DOI: 10.1128/JVI.02579-07  0.36
2008 Koelsch KK, Liu L, Haubrich R, May S, Havlir D, Günthard HF, Ignacio CC, Campos-Soto P, Little SJ, Shafer R, Robbins GK, D'Aquila RT, Kawano Y, Young K, Dao P, ... ... Richman DD, et al. Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro. The Journal of Infectious Diseases. 197: 411-9. PMID 18248304 DOI: 10.1086/525283  0.36
2008 Cachay ER, Frost SD, Poon AF, Looney D, Rostami SM, Pacold ME, Richman DD, Little SJ, Smith DM. Herpes simplex virus type 2 acquisition during recent HIV infection does not influence plasma HIV levels. Journal of Acquired Immune Deficiency Syndromes (1999). 47: 592-6. PMID 18197122 DOI: 10.1097/QAI.0b013e318163bd87  0.36
2007 Richman DD. Advances in the management of HIV-HBV coinfection. Antiviral Therapy. 12: H1. PMID 18284177  0.36
2007 Poon AF, Kosakovsky Pond SL, Richman DD, Frost SD. Mapping protease inhibitor resistance to human immunodeficiency virus type 1 sequence polymorphisms within patients. Journal of Virology. 81: 13598-607. PMID 17913806 DOI: 10.1128/JVI.01570-07  0.36
2007 Smith DM, Wong JK, Shao H, Hightower GK, Mai SH, Moreno JM, Ignacio CC, Frost SD, Richman DD, Little SJ. Long-term persistence of transmitted HIV drug resistance in male genital tract secretions: implications for secondary transmission. The Journal of Infectious Diseases. 196: 356-60. PMID 17597449 DOI: 10.1086/519164  0.36
2007 Dhillon AK, Donners H, Pantophlet R, Johnson WE, Decker JM, Shaw GM, Lee FH, Richman DD, Doms RW, Vanham G, Burton DR. Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors. Journal of Virology. 81: 6548-62. PMID 17409160 DOI: 10.1128/JVI.02749-06  0.36
2007 Poon AF, Kosakovsky Pond SL, Bennett P, Richman DD, Leigh Brown AJ, Frost SD. Adaptation to human populations is revealed by within-host polymorphisms in HIV-1 and hepatitis C virus. Plos Pathogens. 3: e45. PMID 17397261 DOI: 10.1371/journal.ppat.0030045  0.36
2007 Cachay ER, Frost SD, Richman DD, Smith DM, Little SJ. Herpes simplex virus type 2 infection does not influence viral dynamics during early HIV-1 infection. The Journal of Infectious Diseases. 195: 1270-7. PMID 17396995 DOI: 10.1086/513568  0.36
2007 Noviello CM, Pond SL, Lewis MJ, Richman DD, Pillai SK, Yang OO, Little SJ, Smith DM, Guatelli JC. Maintenance of Nef-mediated modulation of major histocompatibility complex class I and CD4 after sexual transmission of human immunodeficiency virus type 1. Journal of Virology. 81: 4776-86. PMID 17329339 DOI: 10.1128/JVI.01793-06  0.36
2007 Richman DD, Wasserman R, Locarnini SA. Antiviral drug resistance: Implications for treatment of HBV infection and similarities with HIV disease Gastroenterology and Hepatology. 3: 15-22.  0.36
2006 Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, ... ... Richman DD, et al. A plea for justice for jailed medical workers. Science (New York, N.Y.). 314: 924-5. PMID 17062652 DOI: 10.1126/science.1136578  0.36
2006 Smith DM, Strain MC, Frost SD, Pillai SK, Wong JK, Wrin T, Liu Y, Petropolous CJ, Daar ES, Little SJ, Richman DD. Lack of neutralizing antibody response to HIV-1 predisposes to superinfection. Virology. 355: 1-5. PMID 16962152 DOI: 10.1016/j.virol.2006.08.009  0.36
2006 Day JR, Martínez LE, Sásik R, Hitchin DL, Dueck ME, Richman DD, Guatelli JC. A computer-based, image-analysis method to quantify HIV-1 infection in a single-cycle infectious center assay. Journal of Virological Methods. 137: 125-33. PMID 16876264 DOI: 10.1016/j.jviromet.2006.06.019  0.36
2006 Pond SL, Frost SD, Grossman Z, Gravenor MB, Richman DD, Brown AJ. Adaptation to different human populations by HIV-1 revealed by codon-based analyses. Plos Computational Biology. 2: e62. PMID 16789820 DOI: 10.1371/journal.pcbi.0020062  0.36
2006 Pillai SK, Pond SL, Liu Y, Good BM, Strain MC, Ellis RJ, Letendre S, Smith DM, Günthard HF, Grant I, Marcotte TD, McCutchan JA, Richman DD, Wong JK. Genetic attributes of cerebrospinal fluid-derived HIV-1 env. Brain : a Journal of Neurology. 129: 1872-83. PMID 16735456 DOI: 10.1093/brain/awl136  0.36
2006 Richman DD. Antiviral drug resistance. Antiviral Research. 71: 117-21. PMID 16621040 DOI: 10.1016/j.antiviral.2006.03.004  0.36
2006 Kumar S, Choi WT, Dong CZ, Madani N, Tian S, Liu D, Wang Y, Pesavento J, Wang J, Fan X, Yuan J, Fritzsche WR, An J, Sodroski JG, Richman DD, et al. SMM-chemokines: A class of unnatural synthetic molecules as chemical probes of chemokine receptor biology and leads for therapeutic development Chemistry and Biology. 13: 69-79. PMID 16426973 DOI: 10.1016/j.chembiol.2005.10.012  0.36
2006 Choi WT, Kumaki Y, Krishna Kumar IM, An J, Richman DD, Sodroski JG, Huang Z. Basic and Translational Research of Chemokine Ligands and Receptors and Development of Novel Therapeutics Drug Discovery Research: New Frontiers in the Post-Genomic Era. 300-335. DOI: 10.1002/9780470131862.ch12  0.36
2005 Frost SD, Wrin T, Smith DM, Kosakovsky Pond SL, Liu Y, Paxinos E, Chappey C, Galovich J, Beauchaine J, Petropoulos CJ, Little SJ, Richman DD. Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection. Proceedings of the National Academy of Sciences of the United States of America. 102: 18514-9. PMID 16339909 DOI: 10.1073/pnas.0504658102  0.36
2005 Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Petropoulos CJ, Richman DD, Little SJ. HIV drug resistance acquired through superinfection. Aids (London, England). 19: 1251-6. PMID 16052079 DOI: 10.1097/01.aids.0000180095.12276.ac  0.36
2005 Smith DM, Richman DD, Little SJ. HIV superinfection Journal of Infectious Diseases. 192: 438-444. PMID 15995957 DOI: 10.1086/431682  0.36
2005 Daar ES, Richman DD. Confronting the emergence of drug-resistant HIV type 1: Impact of antiretroviral therapy on individual and population resistance Aids Research and Human Retroviruses. 21: 343-357. PMID 15929696 DOI: 10.1089/aid.2005.21.343  0.36
2005 Pillai SK, Kosakovsky Pond SL, Woelk CH, Richman DD, Smith DM. Codon volatility does not reflect selective pressure on the HIV-1 genome. Virology. 336: 137-43. PMID 15892955 DOI: 10.1016/j.virol.2005.03.014  0.36
2005 Frost SD, Liu Y, Pond SL, Chappey C, Wrin T, Petropoulos CJ, Little SJ, Richman DD. Characterization of human immunodeficiency virus type 1 (HIV-1) envelope variation and neutralizing antibody responses during transmission of HIV-1 subtype B. Journal of Virology. 79: 6523-7. PMID 15858036 DOI: 10.1128/JVI.79.10.6523-6527.2005  0.36
2005 Strain MC, Little SJ, Daar ES, Havlir DV, Gunthard HF, Lam RY, Daly OA, Nguyen J, Ignacio CC, Spina CA, Richman DD, Wong JK. Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1. The Journal of Infectious Diseases. 191: 1410-8. PMID 15809898 DOI: 10.1086/428777  0.36
2005 Strain MC, Letendre S, Pillai SK, Russell T, Ignacio CC, Günthard HF, Good B, Smith DM, Wolinsky SM, Furtado M, Marquie-Beck J, Durelle J, Grant I, Richman DD, Marcotte T, et al. Genetic composition of human immunodeficiency virus type 1 in cerebrospinal fluid and blood without treatment and during failing antiretroviral therapy. Journal of Virology. 79: 1772-88. PMID 15650202 DOI: 10.1128/JVI.79.3.1772-1788.2005  0.36
2005 Pillai SK, Good B, Pond SK, Wong JK, Strain MC, Richman DD, Smith DM. Semen-specific genetic characteristics of human immunodeficiency virus type 1 env. Journal of Virology. 79: 1734-42. PMID 15650198 DOI: 10.1128/JVI.79.3.1734-1742.2005  0.36
2005 Yang OO, Daar ES, Jamieson BD, Balamurugan A, Smith DM, Pitt JA, Petropoulos CJ, Richman DD, Little SJ, Brown AJ. Human immunodeficiency virus type 1 clade B superinfection: evidence for differential immune containment of distinct clade B strains. Journal of Virology. 79: 860-8. PMID 15613314 DOI: 10.1128/JVI.79.2.860-868.2005  0.36
2004 Richman DD, Little SJ, Smith DM, Wrin T, Petropoulos C, Wong JK. HIV evolution and escape. Transactions of the American Clinical and Climatological Association. 115: 289-303. PMID 17060974  0.36
2004 Dong T, Stewart-Jones G, Chen N, Easterbrook P, Xu X, Papagno L, Appay V, Weekes M, Conlon C, Spina C, Little S, Screaton G, van der Merwe A, Richman DD, McMichael AJ, et al. HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor. The Journal of Experimental Medicine. 200: 1547-57. PMID 15596521 DOI: 10.1084/jem.20032044  0.36
2004 Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Daar ES, Richman DD, Little SJ. Incidence of HIV superinfection following primary infection. Jama. 292: 1177-8. PMID 15353529 DOI: 10.1001/jama.292.10.1177  0.36
2004 Smith DM, Kingery JD, Wong JK, Ignacio CC, Richman DD, Little SJ. The prostate as a reservoir for HIV-1. Aids (London, England). 18: 1600-2. PMID 15238781 DOI: 10.1097/01.aids.0000131364.60081.01  0.36
2004 Richman DD. Benefits and limitations of testing for resistance to HIV drugs Journal of Antimicrobial Chemotherapy. 53: 555-557. PMID 15014064 DOI: 10.1093/jac/dkh157  0.36
2004 Papagno L, Spina CA, Marchant A, Salio M, Rufer N, Little S, Dong T, Chesney G, Waters A, Easterbrook P, Dunbar PR, Shepherd D, Cerundolo V, Emery V, Griffiths P, ... ... Richman DD, et al. Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection. Plos Biology. 2: E20. PMID 14966528 DOI: 10.1371/journal.pbio.0020020  0.36
2004 Leigh Brown AJ, Frost SD, Good B, Daar ES, Simon V, Markowitz M, Collier AC, Connick E, Conway B, Margolick JB, Routy JP, Corbeil J, Hellmann NS, Richman DD, Little SJ. Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection. Journal of Virology. 78: 2242-6. PMID 14963120 DOI: 10.1128/JVI.78.5.2242-2246.2004  0.36
2003 Haas DW, Wilkinson GR, Kuritzkes DR, Richman DD, Nicotera J, Mahon LF, Sutcliffe C, Siminski S, Andersen J, Coughlin K, Clayton EW, Haines J, Marshak A, Saag M, Lawrence J, et al. A multi-investigator/institutional DNA bank for AIDS-related human genetic studies: AACTG Protocol A5128. Hiv Clinical Trials. 4: 287-300. PMID 14583845 DOI: 10.1310/MUQC-QXBC-8118-BPM5  0.36
2003 Gulick RM, Meibohm A, Havlir D, Eron JJ, Mosley A, Chodakewitz JA, Isaacs R, Gonzalez C, McMahon D, Richman DD, Robertson M, Mellors JW. Six-year follow-up of HIV-1-infected adults in a clinical trial of antiretroviral therapy with indinavir, zidovudine, and lamivudine Aids. 17: 2345-2349. PMID 14571186 DOI: 10.1097/00002030-200311070-00009  0.36
2003 Ali A, Pillai S, Ng H, Lubong R, Richman DD, Jamieson BD, Ding Y, McElrath MJ, Guatelli JC, Yang OO. Broadly increased sensitivity to cytotoxic T lymphocytes resulting from Nef epitope escape mutations. Journal of Immunology (Baltimore, Md. : 1950). 171: 3999-4005. PMID 14530319 DOI: 10.4049/jimmunol.171.8.3999  0.36
2003 Strain MC, Günthard HF, Havlir DV, Ignacio CC, Smith DM, Leigh-Brown AJ, Macaranas TR, Lam RY, Daly OA, Fischer M, Opravil M, Levine H, Bacheler L, Spina CA, Richman DD, et al. Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence. Proceedings of the National Academy of Sciences of the United States of America. 100: 4819-24. PMID 12684537 DOI: 10.1073/pnas.0736332100  0.36
2003 Richman DD, Wrin T, Little SJ, Petropoulos CJ. Rapid evolution of the neutralizing antibody response to HIV type 1 infection Proceedings of the National Academy of Sciences of the United States of America. 100: 4144-4149. PMID 12644702 DOI: 10.1073/pnas.0630530100  0.36
2003 Anton PA, Mitsuyasu RT, Deeks SG, Scadden DT, Wagner B, Huang C, Macken C, Richman DD, Christopherson C, Borellini F, Lazar R, Hege KM. Multiple measures of HIV burden in blood and tissue are correlated with each other but not with clinical parameters in aviremic subjects Aids. 17: 53-63. PMID 12478069 DOI: 10.1097/00002030-200301030-00008  0.36
2003 Stuyver LJ, Locarnini SA, Lok A, Richman DD, Carman WF, Dienstag JL, Schinazi RF. Nomenclature for antiviral resistant human hepatitis B virus mutations in the polymerase region Frontiers in Viral Hepatitis. 335-351. DOI: 10.1016/B978-044450986-4/50079-5  0.36
2002 Epstein BJ. Drug resistance among patients recently infected with HIV. The New England Journal of Medicine. 347: 1889-90; author repl. PMID 12466517 DOI: 10.1056/NEJM200212053472315  0.36
2002 Haubrich RH, Kemper CA, Hellmann NS, Keiser PH, Witt MD, Forthal DN, Leedom J, Leibowitz M, Whitcomb JM, Richman D, McCutchan JA. The clinical relevance of non-nucleoside reverse transcriptase inhibitor hypersusceptibility: a prospective cohort analysis. Aids (London, England). 16: F33-40. PMID 12370520 DOI: 10.1097/00002030-200210180-00001  0.36
2002 Bennett KK, DeGruttola VG, Marschner IC, Havlir DV, Richman DD. Baseline predictors of CD4 T-lymphocyte recovery with combination antiretroviral therapy Journal of Acquired Immune Deficiency Syndromes. 31: 20-26. PMID 12352146  0.36
2002 Strain MC, Richman DD, Wong JK, Levine H. Spatiotemporal dynamics of HIV propagation. Journal of Theoretical Biology. 218: 85-96. PMID 12297072 DOI: 10.1006/jtbi.2002.3055  0.36
2002 Deeks SG, Wagner B, Anton PA, Mitsuyasu RT, Scadden DT, Huang C, Macken C, Richman DD, Christopherson C, June CH, Lazar R, Broad DF, Jalali S, Hege KM. A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy Molecular Therapy. 5: 788-797. PMID 12027564 DOI: 10.1006/mthe.2002.0611  0.36
2002 Appay V, Dunbar PR, Callan M, Klenerman P, Gillespie GM, Papagno L, Ogg GS, King A, Lechner F, Spina CA, Little S, Havlir DV, Richman DD, Gruener N, Pape G, et al. Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nature Medicine. 8: 379-85. PMID 11927944 DOI: 10.1038/nm0402-379  0.36
2002 Appay V, Papagno L, Spina CA, Hansasuta P, King A, Jones L, Ogg GS, Little S, McMichael AJ, Richman DD, Rowland-Jones SL. Dynamics of T cell responses in HIV infection. Journal of Immunology (Baltimore, Md. : 1950). 168: 3660-6. PMID 11907132 DOI: 10.4049/jimmunol.168.7.3660  0.36
2002 Appay V, Hansasuta P, Sutton J, Schrier RD, Wong JK, Furtado M, Havlir DV, Wolinsky SM, McMichael AJ, Richman DD, Rowland-Jones SL, Spina CA. Persistent HIV-1-specific cellular responses despite prolonged therapeutic viral suppression. Aids (London, England). 16: 161-70. PMID 11807299 DOI: 10.1097/00002030-200201250-00004  0.36
2002 Lange JMA, Richman DD. Antiviral Therapy in 2003 Antiviral Therapy. 7: 149.  0.36
2001 Richman DD, Johnson VA, Mayers DM, Shirasaka T, O'Brien MC, Mitsuya H. In vitro evaluation of experimental agents for anti-HIV activity. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 12.9. PMID 18432713 DOI: 10.1002/0471142735.im1209s08  0.36
2001 Douek DC, Betts MR, Hill BJ, Little SJ, Lempicki R, Metcalf JA, Casazza J, Yoder C, Adelsberger JW, Stevens RA, Baseler MW, Keiser P, Richman DD, Davey RT, Koup RA. Evidence for increased T cell turnover and decreased thymic output in HIV infection Journal of Immunology. 167: 6663-6668. PMID 11714838 DOI: 10.4049/jimmunol.167.11.6663  0.36
2001 Brooun A, Richman DD, Kornbluth RS. HIV-1 Preintegration Complexes Preferentially Integrate into Longer Target DNA Molecules in Solution as Detected by a Sensitive, Polymerase Chain Reaction-based Integration Assay Journal of Biological Chemistry. 276: 46946-46952. PMID 11595745 DOI: 10.1074/jbc.M108000200  0.36
2001 Bühler B, Lin Y, Morris G, Olson AJ, Wong C, Richman DD, Elder JH, Torbett BE. Viral evolution in response to the broad-based retroviral protease inhibitor TL-3 Journal of Virology. 75: 9502-9508. PMID 11533212 DOI: 10.1128/JVI.75.19.9502-9508.2001  0.36
2001 Havlir DV, Gilbert PB, Bennett K, Collier AC, Hirsch MS, Tebas P, Adams EM, Wheat LJ, Goodwin D, Schnittman S, Holohan MK, Richman DD. Effects of treatment intensification with hydroxyurea in HIV-infected patients with virologic suppression. Aids (London, England). 15: 1379-88. PMID 11504959 DOI: 10.1097/00002030-200107270-00007  0.36
2001 Richman DD. Antiretroviral activity of emtricitabine, a potent nucleoside reverse transcriptase inhibitor Antiviral Therapy. 6: 83-88. PMID 11491420  0.36
2001 Horner AA, Datta SK, Takabayashi K, Belyakov IM, Hayashi T, Cinman N, Nguyen MD, Van Uden JH, Berzofsky JA, Richman DD, Raz E. Immunostimulatory DNA-based vaccines elicit multifaceted immune responses against HIV at systemic and mucosal sites. Journal of Immunology (Baltimore, Md. : 1950). 167: 1584-91. PMID 11466380 DOI: 10.4049/jimmunol.167.3.1584  0.36
2001 Hammond JL, Koontz DL, Bazmi HZ, Beadle JR, Hostetler SE, Kini GD, Aldern KA, Richman DD, Hostetler KY, Mellors JW. Alkylglycerol prodrugs of phosphonoformate are potent in vitro inhibitors of nucleoside-resistant human immunodeficiency virus type 1 and select for resistance mutations that suppress zidovudine resistance. Antimicrobial Agents and Chemotherapy. 45: 1621-8. PMID 11353603 DOI: 10.1128/AAC.45.6.1621-1628.2001  0.36
2001 Richman DD. HIV chemotherapy Nature. 410: 995-1001. PMID 11309630 DOI: 10.1038/35073673  0.36
2001 Stuyver LJ, Locarnini SA, Lok A, Richman DD, Carman WF, Dienstag JL, Schinazi RF, Bartholomeusz A, Di Bisceglie A, De Man RA, Dusheiko G, Furman PA, La Colla P, Lai CL, Lau JYN, et al. Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region Hepatology. 33: 751-757. PMID 11230757 DOI: 10.1053/jhep.2001.22166  0.36
2001 Genini D, Sheeter D, Rought S, Zaunders JJ, Susin SA, Kroemer G, Richman DD, Carson DA, Corbeil J, Leoni LM. HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 5-6. PMID 11099484 DOI: 10.1096/fj.00-0336fje  0.36
2000 Leigh Brown AJ, Precious HM, Whitcomb JM, Wong JK, Quigg M, Huang W, Daar ES, D'Aquila RT, Keiser PH, Connick E, Hellmann NS, Petropoulos CJ, Richman DD, Little SJ. Reduced susceptibility of human immunodeficiency virus type 1 (HIV-1) from patients with primary HIV infection to nonnucleoside reverse transcriptase inhibitors is associated with variation at novel amino acid sites Journal of Virology. 74: 10269-10273. PMID 11044070 DOI: 10.1128/JVI.74.22.10269-10273.2000  0.36
2000 Gilbert PB, Hanna GJ, De Gruttola V, Martinez-Picado J, Kuritzkes DR, Johnson VA, Richman DD, D'Aquila RT. Comparative analysis of HIV type 1 genotypic resistance across antiretroviral trial treatment regimens. Aids Research and Human Retroviruses. 16: 1325-36. PMID 11018852 DOI: 10.1089/08892220050140874  0.36
2000 Martinez-Picado J, DePasquale MP, Kartsonis N, Hanna GJ, Wong J, Finzi D, Rosenberg E, Gunthard HF, Sutton L, Savara A, Petropoulos CJ, Hellmann N, Walker BD, Richman DD, Siliciano R, et al. Antiretroviral resistance during successful therapy of HIV type 1 infection. Proceedings of the National Academy of Sciences of the United States of America. 97: 10948-53. PMID 11005867  0.36
2000 Richman DD. The impact of drug resistance on the effectiveness of chemotherapy for chronic hepatitis B Hepatology. 32: 866-867. PMID 11003636  0.36
2000 Babiker A, Bartlett J, Breckenridge A, Collins G, Coombs R, Cooper D, Creagh T, Cross A, Daniels M, Darbyshire J, Dawson D, DeGruttola V, DeMasi R, Dolin R, Eron J, ... ... Richman D, et al. Human immunodeficiency virus type 1 RNA level and CD4 count as prognostic markers and surrogate end points: A meta-analysis Aids Research and Human Retroviruses. 16: 1123-1133. PMID 10954887 DOI: 10.1089/088922200414965  0.36
2000 Hostetler KY, Hammond JL, Kini GD, Hostetler SE, Beadle JR, Aldern KA, Chou TC, Richman DD, Mellors JW. In vitro anti-HIV-1 activity of sn-2-substituted 1-O-octadecyl-sn-glycero-3-phosphonoformate analogues and synergy with zidovudine. Antiviral Chemistry & Chemotherapy. 11: 213-9. PMID 10901292  0.36
2000 Pillay D, Taylor S, Richman DD. Incidence and impact of resistance against approved antiretroviral drugs Reviews in Medical Virology. 10: 231-253. PMID 10891871 DOI: 10.1002/1099-1654(200007/08)10:4<231::AID-RMV290>3.0.CO;2-P  0.36
2000 Appay V, Nixon DF, Donahoe SM, Gillespie GM, Dong T, King A, Ogg GS, Spiegel HM, Conlon C, Spina CA, Havlir DV, Richman DD, Waters A, Easterbrook P, McMichael AJ, et al. HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function. The Journal of Experimental Medicine. 192: 63-75. PMID 10880527 DOI: 10.1084/jem.192.1.63  0.36
2000 Richman DD. Principles of HIV resistance testing and overview of assay performance characteristics Antiviral Therapy. 5: 27-31. PMID 10846590  0.36
2000 O'Brien TR, McDermott DH, Ioannidis JP, Carrington M, Murphy PM, Havlir DV, Richman DD. Effect of chemokine receptor gene polymorphisms on the response to potent antiretroviral therapy. Aids (London, England). 14: 821-6. PMID 10839590 DOI: 10.1097/00002030-200005050-00008  0.36
2000 Hanna GJ, Johnson VA, Kuritzkes DR, Richman DD, Brown AJ, Savara AV, Hazelwood JD, D'Aquila RT. Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine. The Journal of Infectious Diseases. 181: 904-11. PMID 10720511 DOI: 10.1086/315329  0.36
2000 Richman DD. Normal physiology and HIV pathophysiology of human T-cell dynamics Journal of Clinical Investigation. 105: 565-566. PMID 10712427  0.36
2000 Günthard HF, Wong JK, Spina CA, Ignacio C, Kwok S, Christopherson C, Hwang J, Haubrich R, Havlir D, Richman DD. Effect of influenza vaccination on viral replication and immune response in persons infected with human immunodeficiency virus receiving potent antiretroviral therapy. The Journal of Infectious Diseases. 181: 522-31. PMID 10669335 DOI: 10.1086/315260  0.36
2000 Havlir DV, Hellmann NS, Petropoulos CJ, Whitcomb JM, Collier AC, Hirsch MS, Tebas P, Sommadossi JP, Richman DD. Drug susceptibility in HIV infection after viral rebound in patients receiving indinavir-containing regimens. Jama. 283: 229-34. PMID 10634339 DOI: 10.1001/jama.283.2.229  0.36
2000 Lange JMA, Richman DD. Antiviral therapy in 2000 Antiviral Therapy. 5: 1.  0.36
1999 Lange JMA, Richman DD. 6th Conference on Retroviruses and Opportunistic Infections, Chicago, January 31-February 4 1999: Editorial Antiviral Therapy. 4: 5-6. PMID 10682122  0.36
1999 Zhang Z, Schuler T, Zupancic M, Wietgrefe S, Staskus KA, Reimann KA, Reinhart TA, Rogan M, Cavert W, Miller CJ, Veazey RS, Notermans D, Little S, Danner SA, Richman DD, et al. Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells. Science (New York, N.Y.). 286: 1353-7. PMID 10558989 DOI: 10.1126/science.286.5443.1353  0.36
1999 Little SJ, Daar ES, D'Aquila RT, Keiser PH, Connick E, Whitcomb JM, Hellmann NS, Petropoulos CJ, Sutton L, Pitt JA, Rosenberg ES, Koup RA, Walker BD, Richman DD. Reduced antiretroviral drug susceptibility among patients with primary HIV infection. Jama. 282: 1142-9. PMID 10501117 DOI: 10.1001/jama.282.12.1142  0.36
1999 Little SJ, McLean AR, Spina CA, Richman DD, Havlir DV. Viral dynamics of acute HIV-1 infection. The Journal of Experimental Medicine. 190: 841-50. PMID 10499922 DOI: 10.1084/jem.190.6.841  0.36
1999 Craig HM, Pandori MW, Riggs NL, Richman DD, Guatelli JC. Analysis of the SH3-binding region of HIV-1 nef: partial functional defects introduced by mutations in the polyproline helix and the hydrophobic pocket. Virology. 262: 55-63. PMID 10489340 DOI: 10.1006/viro.1999.9897  0.36
1999 Zhang ZQ, Schuler T, Cavert W, Notermans DW, Gebhard K, Henry K, Havlir DV, Günthard HF, Wong JK, Little S, Feinberg MB, Polis MA, Schrager LK, Schacker TW, Richman DD, et al. Reversibility of the pathological changes in the follicular dendritic cell network with treatment of HIV-1 infection Proceedings of the National Academy of Sciences of the United States of America. 96: 5169-5172. PMID 10220437 DOI: 10.1073/pnas.96.9.5169  0.36
1998 Beadle JR, Kini GD, Aldern KA, Gardner MF, Wright KN, Richman DD, Hostetler KY. Alkylthioglycerol prodrugs of foscarnet: synthesis, oral bioavailability and structure-activity studies in human cytomegalovirus-, herpes simplex virus type 1- and human immunodeficiency virus type 1-infected cells. Antiviral Chemistry & Chemotherapy. 9: 33-40. PMID 9875375 DOI: 10.1177/095632029800900104  0.36
1998 Richman DD. Nailing down another HIV target Nature Medicine. 4: 1232-1233. PMID 9809537 DOI: 10.1038/3209  0.36
1998 Riggs NL, Little SJ, Richman DD, Guatelli JC. Cell-associated viral rNA expression during acute infection with HIV type 1 Aids Research and Human Retroviruses. 14: 1141-1149. PMID 9737585  0.36
1998 Moutouh L, Estaquier J, Richman DD, Corbeil J. Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors Journal of Virology. 72: 8061-8072. PMID 9733846  0.36
1998 Günthard HF, Wong JK, Ignacio CC, Havlir DV, Richman DD. Comparative performance of high-density oligonucleotide sequencing and dideoxynucleotide sequencing of HIV type 1 pol from clinical samples Aids Research and Human Retroviruses. 14: 869-876. PMID 9671215  0.36
1998 Gulick RM, Mellors JW, Havlir D, Eron JJ, Gonzalez C, McMahon D, Jonas L, Meibohm A, Holder D, Schleif WA, Condra JH, Emini EA, Isaacs R, Chodakewitz JA, Richman DD. Simultaneous vs sequential initiation of therapy with indinavir, zidovudine, and lamivudine for HIV-1 infection: 100-week follow-up Journal of the American Medical Association. 280: 35-41. PMID 9660361 DOI: 10.1001/jama.280.1.35  0.36
1998 Kornbluth RS, Kee K, Richman DD. CD40 ligand (CD154) stimulation of macrophages to produce HIV-1-suppressive β-chemokines Proceedings of the National Academy of Sciences of the United States of America. 95: 5205-5210. PMID 9560254  0.36
1998 Havlir DV, Haubrich R, Hwang J, Dunne MW, Currier J, Forthal D, Torriani F, Richman DD, McCutchan JA. Human immunodeficiency virus replication in AIDS patients with Mycobacterium avium complex bacteremia: A case control study Journal of Infectious Diseases. 177: 595-599. PMID 9498437 DOI: 10.1086/514220  0.36
1998 De Jong MD, Boucher CAB, Danner SA, Gazzard B, Griffiths PD, Katlama C, Lange JMA, Richman DD, Vella S. Summary of the international consensus symposium on management of HIV, CMV and hepatitis virus infections Antiviral Research. 37: 1-16. PMID 9497068 DOI: 10.1016/S0166-3542(97)00059-4  0.36
1998 Minshull C, Boucher C, Richman DD. 2nd International Workshop on HIV Drug Resistance and Treatment Strategies, Lake Maggiore, Italy, 24-27 June: Meeting report International Antiviral News. 6: 130-135.  0.36
1998 Kornbluth RS, Kee K, Richman DD. CD40 ligand (CD154) stimulates macrophages to produce HIV-suppressive β-chemokines Faseb Journal. 12.  0.36
1997 Lange JM, Richman DD. The first blow is half the battle Antiviral Therapy. 2: 132-133. PMID 11322268  0.36
1997 Fischl MA, Richman DD, Saag M, Meng TC, Squires KE, Holden-Wiltse J, Meehan PM. Safety and antiviral activity of combination therapy with zidovudine, zalcitabine, and two doses of interferon-alpha2a in patients with HIV. AIDS Clinical Trials Group Study 197. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 16: 247-53. PMID 9402071 DOI: 10.1097/00042560-199712010-00005  0.36
1997 Finzi D, Hermankova M, Pierson T, Carruth LM, Buck C, Chaisson RE, Quinn TC, Chadwick K, Margolick J, Brookmeyer R, Gallant J, Markowitz M, Ho DD, Richman DD, Siliciano RF. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science (New York, N.Y.). 278: 1295-300. PMID 9360927 DOI: 10.1126/science.278.5341.1295  0.36
1997 Wong JK, Hezareh M, Günthard HF, Havlir DV, Ignacio CC, Spina CA, Richman DD. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science (New York, N.Y.). 278: 1291-5. PMID 9360926 DOI: 10.1126/science.278.5341.1291  0.36
1997 Gulick RM, Mellors JW, Havlir D, Eron JJ, Gonzalez C, McMahon D, Richman DD, Valentine FT, Jonas L, Meibohm A, Emini EA, Chodakewitz JA, Deutsch P, Holder D, Schleif WA, et al. Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy New England Journal of Medicine. 337: 734-739. PMID 9287228 DOI: 10.1056/NEJM199709113371102  0.36
1997 Rosowsky A, Fu H, Pai N, Mellors J, Richman DD, Hostetler KY. Synthesis and in vitro activity of long-chain 5'-O- [(alkoxycarbonyl)phosphinyl]-3'axido-3'-azido-3'-deoxythymidines against wild-type and AZT- and foscarnet-resistant strains of HIV-1 Journal of Medicinal Chemistry. 40: 2482-2490. PMID 9258355 DOI: 10.1021/jm970172f  0.36
1997 Roman M, Martin-Orozco E, Goodman JS, Nguyen MD, Sato Y, Ronaghy A, Kornbluth RS, Richman DD, Carson DA, Raz E. Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants Nature Medicine. 3: 849-854. PMID 9256274 DOI: 10.1038/nm0897-849  0.36
1997 Fischl MA, Richman DD, Flexner C, Para MF, Haubrich R, Karim A, Yeramian P, Holden-Wiltse J, Meehan PM. Phase I/II study of the toxicity, pharmacokinetics, and activity of the HIV protease inhibitor SC-52151 Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 15: 28-34. PMID 9215651  0.36
1997 Spina CA, Prince HE, Richman DD. Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro. The Journal of Clinical Investigation. 99: 1774-85. PMID 9120023 DOI: 10.1172/JCI119342  0.36
1997 Gervaix A, West D, Leoni LM, Richman DD, Wong-Staal F, Corbeil J. A new reporter cell line to monitor HIV infection and drug susceptibility in vitro Proceedings of the National Academy of Sciences of the United States of America. 94: 4653-4658. PMID 9114046 DOI: 10.1073/pnas.94.9.4653  0.36
1997 Havlir DV, Richman DD. The role of viral dynamics in the pathogenesis of HIV disease and implications for antiviral therapy Springer Seminars in Immunopathology. 18: 267-283. PMID 9089949 DOI: 10.1007/BF00813498  0.36
1997 Leigh Brown AJ, Richman DD. HIV-1: Gambling on the evolution of drug resistance? Nature Medicine. 3: 268-271. PMID 9055846 DOI: 10.1038/nm0397-268  0.36
1997 Richman DD. The impact of human immunodeficiency virus drug resistance on treatment efficacy Antiviral Therapy. 2: 11-15.  0.36
1997 Richman DD. Drug resistance and its implications in the management of HIV infection Antiviral Therapy. 2: 41-58.  0.36
1997 Lange JMA, Richman DD. Reflecting on a decade of progress Antiviral Therapy. 2: 4-5.  0.36
1996 Richman DD, Lange JM. Playing with evolution requires planning Antiviral Therapy. 1: 208-209. PMID 11324822  0.36
1996 Bozzette SA, Kanouse DE, Duan N, Berry S, Richman DD. The impact of zidovudine compared with didanosine on health status and functioning in persons with advanced HIV infection and a varying duration of prior zidovudine therapy Antiviral Therapy. 1: 21-32. PMID 11322256  0.36
1996 Lange JM, Richman DD. Can HIV infection be cured? Antiviral Therapy. 1: 126-128. PMID 11322245  0.36
1996 Lange JM, Richman DD. Antiretroviral therapy and clinical trials: what now? Antiviral Therapy. 1: 69-70. PMID 11321181  0.36
1996 Richman DD. New strategies to combat HIV drug resistance Hospital Practice. 31: 47-66. PMID 9119931  0.36
1996 Havlir DV, Eastman S, Gamst A, Richman DD. Nevirapine-resistant human immunodeficiency virus: Kinetics of replication and estimated prevalence in untreated patients Journal of Virology. 70: 7894-7899. PMID 8892912  0.36
1996 Coombs RW, Welles SL, Hooper C, Reichelderfer PS, D'Aquila RT, Japour AJ, Johnson VA, Kuritzkes DR, Richman DD, Kwok S, Todd J, Jackson JB, Degruttola V, Crumpacker CS, Kahn J. Association of plasma human immunodeficiency virus type 1 RNA level with risk of clinical progression in patients with advanced infection Journal of Infectious Diseases. 174: 704-712. PMID 8843206 DOI: 10.1093/infdis/174.4.704  0.36
1996 Welles SL, Jackson JB, Yen-Lieberman B, Demeter L, Japour AJ, Smeaton LM, Johnson VA, Kuritzkes DR, D'Aquila RT, Reichelderfer PA, Richman DD, Reichman R, Fischl M, Dolin R, Coombs RW, et al. Prognostic value of plasma human immunodeficiency virus type 1 (HIV-1) RNA levels in patients with advanced HIV-1 disease and with little or no prior zidovudine therapy. AIDS Clinical Trials Group Protocol 116A/116B/117 Team. The Journal of Infectious Diseases. 174: 696-703. PMID 8843205 DOI: 10.1093/infdis/174.4.696  0.36
1996 Richman DD. Anteretroviral drug resistance: Mechanisms, pathogenesis, clinical significance Advances in Experimental Medicine and Biology. 394: 383-395. PMID 8815703  0.36
1996 Richman DD. The implications of drug resistance for strategies of combination antiviral chemotherapy Antiviral Research. 29: 31-33. PMID 8721540 DOI: 10.1016/0166-3542(95)00911-6  0.36
1996 Kozal MJ, Shah N, Shen N, Yang R, Fucini R, Merigan TC, Richman DD, Morris D, Hubbell E, Chee M, Gingeras TR. Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays. Nature Medicine. 2: 753-9. PMID 8673920 DOI: 10.1038/nm0796-753  0.36
1996 Richman DD. HIV therapeutics Science. 272: 1886-1888. PMID 8658159 DOI: 10.1126/science.272.5270.1886  0.36
1996 Moutouh L, Corbeil J, Richman DD. Recombination leads to the rapid emergence of HIV-1 dually resistant mutants under selective drug pressure Proceedings of the National Academy of Sciences of the United States of America. 93: 6106-6111. PMID 8650227 DOI: 10.1073/pnas.93.12.6106  0.36
1996 Havlir DV, Richman DD. Viral dynamics of HIV: Implications for drug development and therapeutic strategies Annals of Internal Medicine. 124: 984-994. PMID 8624066  0.36
1996 Corbeil J, Tremblay M, Richman DD. HIV-induced apoptosis requires the CD4 receptor cytoplasmic tail and is accelerated by interaction of CD4 with p56lck Journal of Experimental Medicine. 183: 39-48. PMID 8551242  0.36
1996 Sato Y, Ueyama K, Maruyama T, Richman DD. Synthesis of the fluoromethyl derivatives of carbocyclic oxetanocin A Nucleosides and Nucleotides. 15: 109-119.  0.36
1995 Richman DD. Clinical significance of drug resistance in human immunodeficiency virus Clinical Infectious Diseases. 21. PMID 8845446 DOI: 10.1093/clinids/21.Supplement_2.S166  0.36
1995 Richman DD. Drug resistance in relation to pathogenesis Aids (London, England). 9. PMID 8819569  0.36
1995 Xie H, Voronkov M, Liotta DC, Korba BA, Schinazi RF, Richman DD, Hostetler KY. Phosphatidyl-2',3'-dideoxy-3'-thiacytidine: synthesis and antiviral activity in hepatitis B-and HIV-1-infected cells. Antiviral Research. 28: 113-20. PMID 8585765 DOI: 10.1016/0166-3542(95)00042-K  0.36
1995 Corbeil J, Richman DD. Productive infection and subsequent interaction of CD4-gp120 at the cellular membrane is required for HIV-induced apoptosis of CD4+ T cells Journal of General Virology. 76: 681-690. PMID 7897356  0.36
1995 Spina CA, Guatelli JC, Richman DD. Establishment of a stable, inducible form of human immunodeficiency virus type 1 DNA in quiescent CD4 lymphocytes in vitro Journal of Virology. 69: 2977-2988. PMID 7707524  0.36
1995 Richman DD. Human immunodeficiency virus. Protease uninhibited Nature. 374: 494. PMID 7700370  0.36
1995 Richman DD, Havlir D. Early Versus Delayed Treatment of HIV Infection: Zidovudine Should be Given Before Symptoms Develop Drugs. 49: 9-16. PMID 7614902 DOI: 10.2165/00003495-199500491-00005  0.36
1995 Havlir D, Mc Laughlin MM, Richman DD. A pilot study to evaluate the development of resistance to nevirapine in asymptomatic human immunodeficiency virus-infected patients with cd4 cell counts of >500/mm3: Aids clinical trials group protocol 208 Journal of Infectious Diseases. 172: 1379-1383. PMID 7594683 DOI: 10.1093/infdis/172.5.1379  0.36
1995 Haubrich RH, Flexner C, Lederman MM, Hirsch M, Pettinelli CP, Ginsberg R, Lietman P, Hamzeh FM, Spector SA, Richman DD, Hammer S, Cooley T, Gulick R, Sullivan M, Spina C, et al. A randomized trial of the activity and safety of ro 24-7429 (tat antagonist) versus nucleoside for human immunodeficiency virus infection Journal of Infectious Diseases. 172: 1246-1252. PMID 7594660 DOI: 10.1093/infdis/172.5.1246  0.36
1995 Kimberlin DW, Couch RB, Galasso GJ, Richman DD, Whitley RJ. Research initiatives in studies of antiviral resistance and consensus points and recommendations Antiviral Research. 26: 439-452. PMID 7574545 DOI: 10.1016/0166-3542(95)00029-L  0.36
1995 Corbeil J, Richman DD. The role of surface CD4 in HIV-induced apoptosis Advances in Experimental Medicine and Biology. 374: 91-99. PMID 7572403  0.36
1995 Chowers MY, Pandori MW, Spina CA, Richman DD, Guatelli JC. The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation. Virology. 212: 451-7. PMID 7571414 DOI: 10.1006/viro.1995.1502  0.36
1995 Proudfoot JR, Hargrave KD, Kapadia SR, Patel UR, Grozinger KG, McNeil DW, Cullen E, Cardozo M, Tong L, Kelly TA. Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. 4. 2-Substituted dipyridodiazepinones as potent inhibitors of both wild-type and cysteine-181 HIV-1 reverse transcriptase enzymes. Journal of Medicinal Chemistry. 38: 4830-8. PMID 7490732  0.36
1995 Havlir D, Richman DD. Antiretroviral therapy Current Opinion in Infectious Diseases. 8: 66-73. DOI: 10.1097/00001432-199502000-00014  0.36
1995 Richman DD. Consensus symposium on combined antiviral therapy. 25-27 July 1995, Lisbon, Portugal International Antiviral News. 3: 129-131. DOI: 10.1016/0166-3542(95)00909-4  0.36
1995 Pillay D, Bryant M, Getman D, Richman DD. HIV-1 protease inhibitors: Their development, mechanism of action and clinical potential Reviews in Medical Virology. 5: 23-33. DOI: 10.1002/rmv.1980050104  0.36
1995 Richman DD. Protease uninhibited Nature. 374: 494.  0.36
1995 Richman DD, Luthy R. Foreword Drugs. 49.  0.36
1994 Corbeil J, Rapaport E, Richman DD, Looney DJ. Antiproliferative effect of retinoid compounds on Kaposi's sarcoma cells Journal of Clinical Investigation. 93: 1981-1986. PMID 8182129  0.36
1994 Gallant JE, Moore RD, Richman DD, Keruly J, Chaisson RE. Risk factors for Kaposi's sarcoma in patients with advanced human immunodeficiency virus disease treated with zidovudine Archives of Internal Medicine. 154: 566-572. PMID 8122950 DOI: 10.1001/archinte.154.5.566  0.36
1994 Corbeil J, Richman DD, Wrasidlo W, Nicolaou KC, Looney DJ. Antiproliferative Effects of Enediynes on AIDS-derived Kaposi's Sarcoma Cells1 Cancer Research. 54: 4270-4273. PMID 8044770  0.36
1994 van Wijk GMT, Hostetler KY, Kroneman E, Richman DD, Sridhar CN, Kumar R, van den Bosch H. Synthesis and antiviral activity of 3′-azido-3′-deoxythymidine triphosphate distearoylglycerol: a novel phospholipid conjugate of the anti-HIV agent AZT Chemistry and Physics of Lipids. 70: 213-222. PMID 8033292 DOI: 10.1016/0009-3084(94)90089-2  0.36
1994 Riggs NL, Little SJ, Richman DD, Guatelli JC. Biological importance and cooperativity of HIV-1 regulatory gene splice acceptors Virology. 202: 264-271. PMID 8009838 DOI: 10.1006/viro.1994.1342  0.36
1994 Little SJ, Riggs NL, Chowers MY, Fitch NJ, Richman DD, Spina CA, Guatelli JC. Cell surface CD4 downregulation and resistance to superinfection induced by a defective provirus of HIV-1. Virology. 205: 578-82. PMID 7975260 DOI: 10.1006/viro.1994.1683  0.36
1994 Pauza CD, Trivedi P, McKechnie TS, Richman DD, Graziano FM. 2-LTR Circular Viral DNA as a Marker for Human Immunodeficiency Virus Type 1 Infection in Vivo Virology. 205: 470-478. PMID 7975248 DOI: 10.1006/viro.1994.1667  0.36
1994 Hostetler KY, Richman DD, Forssen EA, Selk L, Basava R, Gardner MF, Parker S, Basava C. Phospholipid prodrug inhibitors of the HIV protease. Antiviral activity and pharmacokinetics in rats Biochemical Pharmacology. 48: 1399-1404. PMID 7945439 DOI: 10.1016/0006-2952(94)90563-0  0.36
1994 Richman DD, Bozzette SA. The impact of the syncytium-inducing phenotype of human immunodeficiency virus on disease progression Journal of Infectious Diseases. 169: 968-974. PMID 7909549 DOI: 10.1093/infdis/169.5.968  0.36
1994 Spina CA, Kwoh TJ, Chowers MY, Guatelli JC, Richman DD. The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes Journal of Experimental Medicine. 179: 115-123. PMID 7903679 DOI: 10.1084/jem.179.1.115  0.36
1994 Richman DD. Drug resistance in viruses Trends in Microbiology. 2: 401-407. PMID 7850209 DOI: 10.1016/0966-842X(94)90619-X  0.36
1994 Richman DD. Resistance, drug failure, and disease progression Aids Research and Human Retroviruses. 10: 901-905. PMID 7811540  0.36
1994 Meylan PRA, Kornbluth RS, Zbinden I, Richman DD. Influence of host cell type and V3 loop of the surface glycoprotein on susceptibility of human immunodeficiency virus type 1 to polyanion compounds Antimicrobial Agents and Chemotherapy. 38: 2910-2916. PMID 7695283  0.36
1994 Hostetler KY, Richman DD, Sridhar CN, Felgner PL, Felgner J, Ricci J, Gardner MF, Selleseth DW, Ellis MN. Phosphatidylazidothymidine and phosphatidyl-ddC: Assessment of uptake in mouse lymphoid tissues and antiviral activities in human immunodeficiency virus-infected cells and in Rauscher leukemia virus-infected mice Antimicrobial Agents and Chemotherapy. 38: 2792-2797. PMID 7695264 DOI: 10.1128/AAC.38.12.2792  0.36
1994 Kornbluth RS, Matsuzaki H, Meylan PRA, Richman DD. Interferon interactions with HIV1 in macrophages Research in Immunology. 145: 664-668. PMID 7538687 DOI: 10.1016/S0923-2494(05)80051-3  0.36
1994 Nájera I, Richman DD, Olivares I, Rojas JM, Peinado MA, Perucho M, Nájera R, López-Galíndez C. Natural occurrence of drug resistance mutations in the reverse transcriptase of human immunodeficiency virus type 1 isolates. Aids Research and Human Retroviruses. 10: 1479-88. PMID 7534096 DOI: 10.1089/aid.1994.10.1479  0.36
1994 Connell EV, Hsu MC, Richman DD. Combinative interactions of a human immunodeficiency virus (HIV) Tat antagonist with HIV reverse transcriptase inhibitors and an HIV protease inhibitor Antimicrobial Agents and Chemotherapy. 38: 348-352. PMID 7514858  0.36
1994 Sato Y, Maruyama T, Utzumi K, Richman DD. Synthesis and anti-hiv activity of 6-substituted purine 2'-deoxy-2’-fluororibosides1) Nucleosides and Nucleotides. 13: 527-537. DOI: 10.1080/15257779408013260  0.36
1994 Maruyama T, Utsumi K, Sato Y, Richman DD. Synthesis and anti-hiv activity of 2-substituted 2 ‘-deoxy-2’-fluoroadenosines1^ Nucleosides and Nucleotides. 13: 1219-1230. DOI: 10.1080/15257779408012146  0.36
1994 Havlir D, Richman DD. Zidovudine should be given before HIV-positive individuals develop symptoms Reviews in Medical Virology. 4: 75-80.  0.36
1993 Sidtis JJ, Gatsonis C, Price RW, Singer EJ, Collier AC, Richman DD, Hirsch MS, Schaerf FW, Fischl MA, Kieburtz K, Simpson D, Koch MA, Feinberg J, Dafni U, Kennedy C, et al. Zidovudine treatment of the AIDS dementia complex: Results of a placebo-controlled trial Annals of Neurology. 33: 343-349. PMID 8489204 DOI: 10.1002/ana.410330403  0.36
1993 Meylan PRA, Spina CA, Richman DD, Kornbluth RS. In vitro differentiation of monocytoid THP-1 cells affects their permissiveness for HIV strains: A model system for studying the cellular basis of HIV differential tropism Virology. 193: 256-267. PMID 8438570 DOI: 10.1006/viro.1993.1121  0.36
1993 Kornbluth RS, Rhodes J, Richman DD. Recovery of infectious HIV following the passage of apoptotic cellular debris through phagocytic macrophages Chest. 103. PMID 8428523  0.36
1993 Pauza CD, Kornbluth R, Emau P, Richman DD, Deftos LJ. Vitamin D3 compounds regulate human immunodeficiency virus type 1 replication in U937 monoblastoid cells and in monocyte-derived macrophages Journal of Leukocyte Biology. 53: 157-164. PMID 8383166  0.36
1993 Kohsaka H, Taniguchi A, Richman DD, Carson DA. Microtiter format gene quantification by covalent capture of competitive PCR products: Application to HIV-1 detection Nucleic Acids Research. 21: 3469-3472. PMID 8346024 DOI: 10.1093/nar/21.15.3469  0.36
1993 Richman DD. Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents Antimicrobial Agents and Chemotherapy. 37: 1207-1213. PMID 8328771  0.36
1993 Schoenfeld DA, Finkelstein DM, Richman DD. Designing phase II studies of chemotherapy for HIV infection using CD4 as an end-point Aids. 7: 955-958. PMID 8102853  0.36
1993 Skowron G, Bozzette SA, Lim L, Pettinelli CB, Schaumburg HH, Arezzo J, Fischl MA, Powderly WG, Gocke DJ, Richman DD, Pottage JC, Antoniskis D, McKinley GF, Hyslop NE, Ray G, et al. Alternating and intermittent regimens of zidovudine and dideoxycytidine in patients with AIDS or AIDS-related complex. Annals of Internal Medicine. 118: 321-30. PMID 8094279 DOI: 10.7326/0003-4819-118-5-199303010-00001  0.36
1993 Meylan PRA, Guatelli JC, Munis JR, Richman DD, Kornbluth RS. Mechanisms for the inhibition of HIV replication by interferons-α, -β, and -γ in primary human macrophages Virology. 193: 138-148. PMID 7679856 DOI: 10.1006/viro.1993.1110  0.36
1993 Richman DD. Playing chess with reverse transcriptase Nature. 361: 588-589. PMID 7679776  0.36
1992 Meylan PRA, Munis JR, Richman DD, Kornbluth RS. Concurrent human immunodeficiency virus and mycobacterial infection of macrophages in vitro does not reveal any reciprocal effect Journal of Infectious Diseases. 165: 80-86. PMID 1727900 DOI: 10.1093/infdis/165.1.80  0.36
1992 Munis JR, Kornbluth RS, Guatelli JC, Richman DD. Ordered appearance of human immunodeficiency virus type 1 nucleic acids following high multiplicity infection of macrophages Journal of General Virology. 73: 1899-1906. PMID 1645135  0.36
1992 Day JJ, Grant I, Atkinson JH, Brysk LT, McCutchan JA, Hesselink JR, Heaton RK, Weinrich JD, Spector SA, Richman DD. Incidence of AIDS dementia in a two-year follow-up of AIDS and ARC patients on an initial phase II AZT placebo-controlled study: San Diego cohort. The Journal of Neuropsychiatry and Clinical Neurosciences. 4: 15-20. PMID 1627957 DOI: 10.1176/jnp.4.1.15  0.36
1992 Richman DD. Selection of zidovudine-resistant variants of human immunodeficiency virus by therapy Current Topics in Microbiology and Immunology. 176: 131-142. PMID 1600750  0.36
1992 Richman DD. The clinical significance of drug-resistant mutants of human immunodeficiency virus Research in Virology. 143: 130-131. PMID 1594795 DOI: 10.1016/S0923-2516(06)80096-8  0.36
1992 Meylan PRA, Richman DD, Kornbluth RS. Reduced intracellular growth of mycobacteria in human macrophages cultivated at physiologic oxygen pressure American Review of Respiratory Disease. 145: 947-953. PMID 1554224  0.36
1992 Meylan PRA, Tam EK, Kornbluth RS, Richman DD. HIV infectivity is not augmented by treatment with trypsin, Factor Xa or human mast-cell tryptase [3] Aids. 6: 128-130. PMID 1543555  0.36
1992 Meylan PRA, Richman DD, Kornbluth RS. Oxygen tensions and mycobacterial infections Clinical Infectious Diseases. 15: 372-373. PMID 1520772 DOI: 10.1093/clinids/15.2.372  0.36
1992 Chaisson RE, Keruly J, Richman DD, Moore RD. Pneumocystis Prophylaxis and Survival in Patients With Advanced Human Immunodeficiency Virus Infection Treated With Zidovudine Archives of Internal Medicine. 152: 2009-2013. PMID 1417373 DOI: 10.1001/archinte.1992.00400220041007  0.36
1992 Hostetler KY, Richman DD, Carson DA, Stuhmiller LM, Van Wijk GMT, Van den Bosch H. Greatly enhanced inhibition of human immunodeficiency virus type 1 replication in CEM and HT4-6C cells by 3'-deoxythymidine diphosphate dimyristoylglycerol, a lipid prodrug of 3'-deoxythymidine Antimicrobial Agents and Chemotherapy. 36: 2025-2029. PMID 1416896 DOI: 10.1128/AAC.36.9.2025  0.36
1992 Kumar R, Gardner MF, Richman DD, Hostetler KY. Equal inhibition of HIV replication by stereoisomers of phosphatidyl-azidothymidine: Lack of stereospecificity of lysosomal phospholipase A1 Journal of Biological Chemistry. 267: 20288-20292. PMID 1400346  0.36
1992 Hsu MC, Schutt AD, Holly M, Slice LW, Sherman MI, Richman DD, Potash MJ, Volsky DJ. Discovery and characterization of an HIV-1 Tat antagonist. Biochemical Society Transactions. 20: 525-31. PMID 1397654  0.36
1992 Kahn JO, Lagakos SW, Richman DD, Cross A, Pettinelli C, Liou SH, Brown M, Volberding PA, Crumpacker CS, Beall G. A controlled trial comparing continued zidovudine with didanosine in human immunodeficiency virus infection. The NIAID AIDS Clinical Trials Group. The New England Journal of Medicine. 327: 581-7. PMID 1353607 DOI: 10.1056/NEJM199208273270901  0.36
1992 Richman DD. Emergence of mutant HIV reverse transcriptase conferring resistance to AZT Journal of Enzyme Inhibition and Medicinal Chemistry. 6: 55-64. PMID 1285303 DOI: 10.3109/14756369209041356  0.36
1992 Kahn JO, Lagakos SW, Richman DD, Hirschel B. Changing from zidovudine to didanosine for HIV infection Annals of Internal Medicine. 118: 12.  0.36
1991 Richman DD. AZT resistance in isolates of HIV Immunodeficiency Reviews. 2: 315-318. PMID 2059436  0.36
1991 Omary B, Brenner DA, De Grandpre LY, Roebuck KA, Richman DD, Kagnoff MF. HIV-1 infection and expression in human colonic cells: Infection and expression in CD4+ and CD4- cell lines Aids. 5: 275-281. PMID 2059367 DOI: 10.1097/00002030-199103000-00005  0.36
1991 Richman DD. Antiviral therapy of HIV infection Annual Review of Medicine. 42: 69-90. PMID 2035995 DOI: 10.1016/B978-0-12-800964-2.00020-3  0.36
1991 López-Galíndez C, Rojas JM, Nájera R, Richman DD, Perucho M. Characterization of genetic variation and 3'-azido-3'-deoxythymidine- resistance mutations of human immunodeficiency virus by the RNase A mismatch cleavage method. Proceedings of the National Academy of Sciences of the United States of America. 88: 4280-4. PMID 2034672 DOI: 10.1073/pnas.88.10.4280  0.36
1991 Terai C, Kornbluth RS, Pauza CD, Richman DD, Carson DA. Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1 Journal of Clinical Investigation. 87: 1710-1715. PMID 2022741 DOI: 10.1172/JCI115188  0.36
1991 Moore RD, Kessler H, Richman DD, Flexner C, Chaisson RE. Non-Hodgkin’s Lymphoma in Patients With Advanced HIV Infection Treated With Zidovudine Jama: the Journal of the American Medical Association. 265: 2208-2211. PMID 2013953 DOI: 10.1001/jama.1991.03460170062034  0.36
1991 Kagnoff MF, Omary MB, de Grandpre LY, Roebuck KA, Richman DD, Brenner DA. Expression of human immunodeficiency virus-1 in human colonic cells Immunologic Research. 10: 452-455. PMID 1955772 DOI: 10.1007/BF02919741  0.36
1991 Gingeras TR, Prodanovich P, Latimer T, Guatelli JC, Richman DD, Barringer KJ. Use of self-sustained sequence replication amplification reaction to analyze and detect mutations in zidovudine-resistant human immunodeficiency virus Journal of Infectious Diseases. 164: 1066-1074. PMID 1955709 DOI: 10.1093/infdis/164.6.1066  0.36
1991 Wu AW, Rubin HR, Mathews WC, Ware JE, Brysk L, Hardy WD, Bozzette SA, Spector SA, Richman DD. A health status questionnaire using 30 items from the medical outcomes study: Preliminary validation in persons with early HIV infection Medical Care. 29: 786-798. PMID 1875745 DOI: 10.1097/00005650-199108000-00011  0.36
1991 Bozzette SA, Larsen RA, Chiu J, Leal MA, Tilles JG, Richman DD, Leedom JM, McCutchan JA. Fluconazole treatment of persistent Cryptococcus neoformans prostatic infection in AIDS. Annals of Internal Medicine. 115: 285-6. PMID 1854112 DOI: 10.7326/0003-4819-115-4-285  0.36
1991 Hsu MC, Schutt AD, Holly M, Slice LW, Sherman MI, Richman DD, Potash MJ, Volsky DJ. Inhibition of HIV replication in acute and chronic infections in vitro by a Tat antagonist Science. 254: 1799-1802. PMID 1763331  0.36
1991 Richman DD, Guatelli JC, Grimes J, Tsiatis A, Gingeras T. Detection of mutations associated with zidovudine resistance in human immunodeficiency virus by use of the polymerase chain reaction Journal of Infectious Diseases. 164: 1075-1081. PMID 1720152  0.36
1991 Hostetler KY, Carson DA, Richman DD. Phosphatidylazidothymidine: Mechanism of antiretroviral action in CEM cells Journal of Biological Chemistry. 266: 11714-11717. PMID 1711037  0.36
1991 Richman D, Rosenthal AS, Skoog M, Eckner RJ, Chou TC, Sabo JP, Merluzzi VJ. BI-RG-587 is active against zidovudine-resistant human immunodeficiency virus type 1 and synergistic with zidovudine. Antimicrobial Agents and Chemotherapy. 35: 305-8. PMID 1708976 DOI: 10.1128/AAC.35.2.305  0.36
1991 Bozzette SA, Santangelo J, Villasana D, Wright B, Richman DD, Fraser A, Spector SA, Jacobsen C, Hayden E, Schnack J. Peripheral nerve function in persons with asymptomatic or minimally symptomatic hiv disease: Absence of zidovudine neurotoxicity Journal of Acquired Immune Deficiency Syndromes. 4: 851-855. PMID 1654410  0.36
1991 Fischl MA, Richman DD. HIV disease: Pathogenesis and therapy Journal of Acquired Immune Deficiency Syndromes. 4: 1.  0.36
1991 Moore RD, Kessler H, Richman DD. Incidence of non-Hodgkins's lymphoma in zidovudine-treated patients Journal of the American Osteopathic Association. 91: 520.  0.36
1990 Guatelli JC, Gingeras TR, Richman DD. Alternative splice acceptor utilization during human immunodeficiency virus type 1 infection of cultured cells Journal of Virology. 64: 4093-4098. PMID 2384914  0.36
1990 Meylan PR, Richman DD, Kornbluth RS. Characterization and growth in human macrophages of Mycobacterium avium complex strains isolated from the blood of patients with acquired immunodeficiency syndrome Infection and Immunity. 58: 2564-2568. PMID 2370109  0.36
1990 Larder BA, Chesebro B, Richman DD. Susceptibilities of zidovudine-susceptible and -resistant human immunodeficiency virus isolates to antiviral agents determined by using a quantitative plaque reduction assay Antimicrobial Agents and Chemotherapy. 34: 436-441. PMID 2334156  0.36
1990 Guatelli JC, Whitfield KM, Kwoh DY, Barringer KJ, Richman DD, Gingeras TR. Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retroviral replication Proceedings of the National Academy of Sciences of the United States of America. 87: 1874-1878. PMID 2308948 DOI: 10.1073/pnas.87.5.1874  0.36
1990 Munis JR, Richman DD, Kornbluth RS. Human immunodeficiency virus-1 infection of macrophages in vitro neither induces tumor necrosis factor (TNF)/cachectin gene expression nor alters TNF/cachectin induction by lipopolysaccharide Journal of Clinical Investigation. 85: 591-596. PMID 2298923  0.36
1990 Pauza CD, Galindo JE, Richman DD. Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persistent human immunodeficiency virus type 1 infection of CEM cells Journal of Experimental Medicine. 172: 1035-1042. PMID 2212939  0.36
1990 Richman DD. Zidovudine resistance of human immunodeficiency virus Reviews of Infectious Diseases. 12: S507-S512. PMID 2201072 DOI: 10.1093/clinids/12.Supplement_5.S507  0.36
1990 Richman DD. Susceptibility to nucleoside analogues of zidovudine-resistant isolates of human immunodeficiency virus The American Journal of Medicine. 88. PMID 2186629 DOI: 10.1016/0002-9343(90)90414-9  0.36
1990 Kornbluth RS, Munis JR, Oh PS, Meylan PR, Richman DD. Characterization of a macrophage-tropic HIV strain that does not alter macrophage cytokine production yet protects macrophages from superinfection by vesicular stomatitis virus. Aids Research and Human Retroviruses. 6: 1023-6. PMID 2171598  0.36
1990 Meng TC, Fischl MA, Richman DD. AIDS clinical trials group: Phase I/II study of combination 2′,3′-dideoxycytidine and zidovudine in patients with acquired immunodeficiency syndrome (AIDS) and advanced AIDS-related complex The American Journal of Medicine. 88. PMID 2159707 DOI: 10.1016/0002-9343(90)90419-E  0.36
1990 Bozzette SA, Richman DD. Salvage therapy for zidovudine-intolerant HIV-infected patients with alternating and intermittent regimens of zidovudine and dideoxycytidine The American Journal of Medicine. 88. PMID 2159706 DOI: 10.1016/0002-9343(90)90418-D  0.36
1990 Dankner WM, McCutchan JA, Richman DD, Hirata K, Spector SA. Localization of human cytomegalovirus in peripheral blood leukocytes by in situ hybridization Journal of Infectious Diseases. 161: 31-36. PMID 2153186 DOI: 10.1093/infdis/161.1.31  0.36
1990 Richman DD, Grimes JM, Lagakos SW. Effect of stage of disease and drug dose on zidovudine susceptibilities of isolates of human immunodeficiency virus Journal of Acquired Immune Deficiency Syndromes. 3: 743-746. PMID 2114476  0.36
1990 Fischl MA, Parker CB, Pettinelli C, Wulfsohn M, Hirsch MS, Collier AC, Antoniskis D, Ho M, Richman DD, Fuchs E, Merigan TC, Reichman RC, Gold J, Steigbigel N, Leoung GS, et al. A randomized controlled trial of a reduced daily dose of zidovudine in patients with the acquired immunodeficiency syndrome New England Journal of Medicine. 323: 1009-1014. PMID 1977079 DOI: 10.1056/NEJM199010113231501  0.36
1990 Zarling JM, Moran PA, Haffar O, Sias J, Richman DD, Spina CA, Myers DE, Kuebelbeck V, Ledbetter JA, Uckun FM. Inhibition of HIV replication by pokeweed antiviral protein targeted to CD4+ cells by monoclonal antibodies Nature. 347: 92-95. PMID 1975641 DOI: 10.1038/347092a0  0.36
1990 Fischl MA, Richman DD, Hansen N, Collier AC, Carey JT, Para MF, Hardy WD, Dolin R, Powderly WG, Allan JD, Wong B, Merigan TC, McAuliffe VJ, Hyslop NE, Rhame FS, et al. The safety and efficacy of zidovudine (AZT) in the treatment of subjects with mildly symptomatic human immunodeficiency virus type 1 (HIV) infection a double-blind, placebo-controlled trial Annals of Internal Medicine. 112: 727-737. PMID 1970466 DOI: 10.7326/0003-4819-112-10-727  0.36
1990 Frank KB, Connell EV, Holman MJ, Huryn DM, Sluboski BC, Tam SY, Todaro LJ, Weigele M, Richman DD, Mitsuya H. Anabolism and mechanism of action of Ro24-5098, an isomer of 2',3'-dideoxyadenosine (ddA) with anti-HIV activity. Annals of the New York Academy of Sciences. 616: 408-14. PMID 1706575 DOI: 10.1111/j.1749-6632.1990.tb17860.x  0.36
1990 Gingeras TR, Richman DD, Kwoh DY, Guatelli JC. Methodologies for in vitro nucleic acid amplification and their applications Veterinary Microbiology. 24: 235-251. PMID 1701942 DOI: 10.1016/0378-1135(90)90174-T  0.36
1990 Richman DD. Viral drug resistance Current Opinion in Infectious Diseases. 3: 819-823.  0.36
1989 Richman DD. Public access to experimental drug therapy: Aids raises yet another conflict between freedom of the individual and welfare of the individual and public Journal of Infectious Diseases. 159: 412-415. PMID 2915164 DOI: 10.1093/infdis/159.3.412  0.36
1989 Guatelli JC, Gingeras TR, Richman DD. Nucleic acid amplification in vitro: Detection of sequences with low copy numbers and application to diagnosis of human immunodeficiency virus type 1 infection Clinical Microbiology Reviews. 2: 217-226. PMID 2650862  0.36
1989 Woolf NK, Koehrn FJ, Harris JP, Richman DD. Congenital cytomegalovirus labyrinthitis and sensorineural hearing loss in guinea pigs. The Journal of Infectious Diseases. 160: 929-37. PMID 2555420 DOI: 10.1093/infdis/160.6.929  0.36
1989 Larsen RA, Bozzette S, McCutchan JA, Chiu J, Leal MA, Richman DD. Persistent Cryptococcus neoformans infection of the prostate after successful treatment of meningitis. California Collaborative Treatment Group. Annals of Internal Medicine. 111: 125-8. PMID 2545124 DOI: 10.7326/0003-4819-111-2-125  0.36
1989 Heyman RA, Borrelli E, Lesley J, Anderson D, Richman DD, Baird SM, Hyman R, Evans RM. Thymidine kinase obliteration: Creation of transgenic mice with controlled immune deficiency Proceedings of the National Academy of Sciences of the United States of America. 86: 2698-2702. PMID 2539597 DOI: 10.1073/pnas.86.8.2698  0.36
1989 Spector SA, Kennedy C, McCutchan JA, Bozzette SA, Straube RG, Connor JD, Richman DD. The Antiviral Effect of Zidovudine and Ribavirin in Clinical Trials and The Use of p24 Antigen Levels as a Virologic Marker Journal of Infectious Diseases. 159: 822-828. PMID 2496173 DOI: 10.1093/infdis/159.5.822  0.36
1989 Larder BA, Darby G, Richman DD. HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy Science. 243: 1731-1734. PMID 2467383  0.36
1989 Kornbluth RS, Oh PS, Munis JR, Cleveland PH, Richman DD. Interferons and bacterial lipopolysaccharide protect macrophages from productive infection by human immunodeficiency virus in vitro. The Journal of Experimental Medicine. 169: 1137-51. PMID 2466937  0.36
1988 Atkinson JH, Grant I, Kennedy CJ, Richman DD, Spector SA, Mccutchan JA. Prevalence of Psychiatric Disorders Among Men Infected With Human Immunodeficiency Virus: A Controlled Study Archives of General Psychiatry. 45: 859-864. PMID 3415427 DOI: 10.1001/archpsyc.1988.01800330091011  0.36
1988 Smith RS, Viel SB, Fong SS, Parks DE, Westrick S, Richman DD. Simultaneous detection of antibody to the human immunodeficiency virus and of the surface antigen of hepatitis B virus in human serum. The Journal of Infectious Diseases. 157: 812-6. PMID 3346573 DOI: 10.1093/infdis/157.4.812  0.36
1988 Carson DA, Haertle T, Bruce Wasson D, Richman DD. Biochemical genetic analysis of 2′,3′-dideoxyadenosine metabolism in human T lymphocytes Biochemical and Biophysical Research Communications. 151: 788-793. PMID 3258154 DOI: 10.1016/S0006-291X(88)80350-4  0.36
1988 Richman DD. The treatment of HIV infection Aids. 2. PMID 2852501  0.36
1988 Woolf NK, Ochi JW, Silva EJ, Sharp PA, Harris JP, Richman DD. Ganciclovir prophylaxis for cochlear pathophysiology during experimental guinea pig cytomegalovirus labyrinthitis. Antimicrobial Agents and Chemotherapy. 32: 865-72. PMID 2843084 DOI: 10.1128/AAC.32.6.865  0.36
1988 Richman DD. The treatment of HIV infection. Azidothymidine (AZT) and other new antiviral drugs Infectious Disease Clinics of North America. 2: 397-407. PMID 2462584  0.36
1988 Pauza CD, Galindo J, Richman DD. Human immunodeficiency virus infection of monoblastoid cells: Cellular differentiation determines the pattern of virus replication Journal of Virology. 62: 3558-3564. PMID 2458483  0.36
1987 Grant I, Atkinson JH, Hesselink JR, Kennedy CJ, Richman DD, Spector SA, McCutchan JA. Evidence for early central nervous system involvement in the acquired immunodeficiency syndrome (AIDS) and other human immunodeficiency virus (HIV) infections. Studies with neuropsychologic testing and magnetic resonance imaging. Annals of Internal Medicine. 107: 828-36. PMID 3688675 DOI: 10.7326/0003-4819-107-6-828  0.36
1987 Richman DD. Dideoxynucleosides are less inhibitory in vitro against human immunodeficiency virus type 2 (HIV-2) than against HIV-1 Antimicrobial Agents and Chemotherapy. 31: 1879-1881. PMID 3501941  0.36
1987 Richman DD. Developments in rapid viral diagnosis Infectious Disease Clinics of North America. 1: 311-322. PMID 3332792  0.36
1987 Richman DD, Kornbluth RS, Carson DA. Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages Journal of Experimental Medicine. 166: 1144-1149. PMID 2821152 DOI: 10.1084/jem.166.4.1144  0.36
1987 Richman DD, McCutchan JA, Spector SA. Detecting human immunodeficiency virus RNA in peripheral blood mononuclear cells by nucleic acid hybridization Journal of Infectious Diseases. 156: 823-827. PMID 2821128  0.36
1987 Cleveland PH, Richman DD. Enzyme immunofiltration staining assay for immediate diagnosis of herpes simplex virus and varicella-zoster virus directly from clinical specimens Journal of Clinical Microbiology. 25: 416-420. PMID 2434523  0.36
1986 Richman DD, Hostetler KY, Yazaki PJ, Clark S. Fate of influenza a virion proteins after entry into subcellular fractions of LLC cells and the effect of amantadine Virology. 151: 200-210. PMID 3705464 DOI: 10.1016/0042-6822(86)90042-5  0.36
1985 Woolf NK, Harris JP, Ryan AF, Butler DM, Richman DD. Hearing loss in experimental cytomegalovirus infection of the guinea pig inner ear: prevention by systemic immunity. The Annals of Otology, Rhinology, and Laryngology. 94: 350-6. PMID 2992353  0.36
1985 Richman DD, Cleveland PH, Wopschall LJ. Immunoenzymatic staining of viral and chlamydial antigens in cell culture Diagnostic Microbiology and Infectious Disease. 3: 353-358. PMID 2411466 DOI: 10.1016/0732-8893(85)90010-0  0.36
1984 Richman DD, Cleveland PH, Redfield DC, Oxman MN, Wahl GM. Rapid viral diagnosis Journal of Infectious Diseases. 149: 298-310. PMID 6201563  0.36
1984 Harris JP, Woolf NK, Ryan AF, Butler DM, Richman DD. Immunologic and electrophysiological response to cytomegaloviral inner ear infection in the guinea pig. The Journal of Infectious Diseases. 150: 523-30. PMID 6092483  0.36
1983 Richman DD, Cleveland PH, McCormick JB, Johnson KM. Antigenic analysis of strains of Ebola virus: Identification of two Ebola virus serotypes Journal of Infectious Diseases. 147: 268-271. PMID 6827143  0.36
1983 Richman DD. The use of staphylococcal protein A in diagnostic virology Current Topics in Microbiology and Immunology. 104: 159-176. PMID 6347531  0.36
1983 Redfield DC, Richman DD, Albanil S, Oxman MN, Wahl GM. Detection of herpes simplex virus in clinical specimens by DNA hybridization Diagnostic Microbiology and Infectious Disease. 1: 117-128. PMID 6325080  0.36
1982 Hostetler KY, Richman DD. Studies on the mechanism of phospholipid storage induced by amantadine and chloroquine in Madin Darby canine kidney cells Biochemical Pharmacology. 31: 3795-3799. PMID 7159462 DOI: 10.1016/0006-2952(82)90295-7  0.36
1982 Cleveland PH, Richman DD, Oxman MN, Worthen DM. Rapid serological technique for typing herpes simplex viruses Journal of Clinical Microbiology. 15: 402-407. PMID 7076813  0.36
1982 Richman DD, Cleveland PH, Oxman MN, Johnson KM. The binding of staphylococcal protein A by the sera of different animal species Journal of Immunology. 128: 2300-2305. PMID 7061862  0.36
1982 Richman DD, Cleveland PH, Oxman MN. A rapid enzyme immunofiltration technique using monoclonal antibodies to serotype herpes simplex virus Journal of Medical Virology. 9: 299-305. PMID 6286864  0.36
1982 Hostetler KY, Richman DD. Mechanisms of drug-induced lipidosis in cultured kidney cells Clinical Research. 30.  0.36
1981 Richman DD, Yazaki P, Hostetler KY. The intracellular distribution and antiviral activity of amantadine Virology. 112: 81-90. PMID 7245620 DOI: 10.1016/0042-6822(81)90614-0  0.36
1981 Redfield DC, Richman DD, Oxman MN, Kronenberg LH. Psoralen inactivation of influenza and herpes simplex viruses and of virus-infected cells Infection and Immunity. 32: 1216-1226. PMID 6265375  0.36
1981 Richman DD, Cleveland PH, Oxman MN, Zaia JA. A rapid radioimmunoassay using125i-labeled staphylococcal protein a for antibody to varicella-zoster virus Journal of Infectious Diseases. 143: 693-699. PMID 6263987 DOI: 10.1093/infdis/143.5.693  0.36
1980 Brautigam AR, Richman DD, Oxman MN. Rapid typing of herpes simplex virus isolates by deoxyribonucleic acid: Deoxyribonucleic acid hybridization Journal of Clinical Microbiology. 12: 226-234. PMID 6262368  0.36
1979 Catalano MA, Carson DA, Slovin SF, Richman DD, Vaughan JH. Antibodies to Epstein-Barr virus-determined antigens in normal subjects and in patients with seropositive rheumatoid arthritis Proceedings of the National Academy of Sciences of the United States of America. 76: 5825-5828. PMID 230491 DOI: 10.1073/pnas.76.11.5825  0.36
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