Robert L. Modlin - Publications

University of California, Los Angeles, Los Angeles, CA 
Immunology, Microbiology Biology

305 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kelly-Scumpia KM, Choi A, Shirazi R, Bersabe H, Park E, Scumpia PO, Ochoa MT, Yu J, Ma F, Pellegrini M, Modlin RL. ER Stress Regulates Immunosuppressive Function of Myeloid Derived Suppressor Cells in Leprosy that Can Be Overcome in the Presence of IFN-γ. Iscience. 23: 101050. PMID 32339990 DOI: 10.1016/J.Isci.2020.101050  0.4
2019 Tió-Coma M, van Hooij A, Bobosha K, van der Ploeg-van Schip JJ, Banu S, Khadge S, Thapa P, Kunwar CB, Goulart IM, Bekele Y, Hagge DA, Moraes MO, Teles RMB, Pinheiro RO, van Zwet EW, ... ... Modlin RL, et al. Whole blood RNA signatures in leprosy patients identify reversal reactions before clinical onset: a prospective, multicenter study. Scientific Reports. 9: 17931. PMID 31784594 DOI: 10.1038/S41598-019-54213-Y  0.48
2019 Teles RMB, Lu J, Tió-Coma M, Goulart IMB, Banu S, Hagge D, Bobosha K, Ottenhoff T, Pellegrini M, Geluk A, Modlin RL. Identification of a systemic interferon-γ inducible antimicrobial gene signature in leprosy patients undergoing reversal reaction. Plos Neglected Tropical Diseases. 13: e0007764. PMID 31600201 DOI: 10.1371/Journal.Pntd.0007764  0.48
2019 R Andrade P, Mehta M, Lu J, M B Teles R, Montoya D, O Scumpia P, Nunes Sarno E, Ochoa MT, Ma F, Pellegrini M, Modlin RL. The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy. Plos Neglected Tropical Diseases. 13: e0007589. PMID 31344041 DOI: 10.1371/Journal.Pntd.0007589  0.4
2019 Weiss DI, Ma F, Merleev AA, Maverakis E, Gilliet M, Balin SJ, Bryson BD, Ochoa MT, Pellegrini M, Bloom BR, Modlin RL. IL-1β Induces the Rapid Secretion of the Antimicrobial Protein IL-26 from Th17 Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 31235553 DOI: 10.4049/Jimmunol.1900318  0.4
2019 Kim EW, De Leon A, Jiang Z, Radu RA, Martineau AR, Chan ED, Bai X, Su WL, Montoya DJ, Modlin RL, Liu PT. Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis. Msphere. 4. PMID 31167948 DOI: 10.1128/mSphere.00327-19  0.76
2019 Dang AT, Teles RM, Liu PT, Choi A, Legaspi A, Sarno EN, Ochoa MT, Parvatiyar K, Cheng G, Gilliet M, Bloom BR, Modlin RL. Autophagy links antimicrobial activity with antigen presentation in Langerhans cells. Jci Insight. 4. PMID 30996142 DOI: 10.1172/Jci.Insight.126955  0.76
2019 Dang AT, Teles RM, Weiss DI, Parvatiyar K, Sarno EN, Ochoa MT, Cheng G, Gilliet M, Bloom BR, Modlin RL. IL-26 contributes to host defense against intracellular bacteria. The Journal of Clinical Investigation. 130. PMID 30939123 DOI: 10.1172/Jci99550  0.56
2019 Montoya DJ, Andrade P, Silva BJA, Teles RMB, Ma F, Bryson B, Sadanand S, Noel T, Lu J, Sarno E, Arnvig KB, Young D, Lahiri R, Williams DL, Fortune S, ... ... Modlin RL, et al. Dual RNA-Seq of Human Leprosy Lesions Identifies Bacterial Determinants Linked to Host Immune Response. Cell Reports. 26: 3574-3585.e3. PMID 30917313 DOI: 10.1016/J.Celrep.2019.02.109  0.48
2018 Montoya D, Mehta M, Ferguson BG, Teles RMB, Kruzik SR, Cruz D, Pellegrini M, Modlin RL. Plasticity of antimicrobial and phagocytic programs in human macrophages. Immunology. PMID 30357820 DOI: 10.1111/Imm.13013  0.48
2018 Zavala K, Gottlieb CA, Teles RM, Adams JS, Hewison M, Modlin RL, Liu PT. Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN. Plos Neglected Tropical Diseases. 12: e0006815. PMID 30300363 DOI: 10.1371/Journal.Pntd.0006815  0.76
2018 Balin SJ, Pellegrini M, Klechevsky E, Won ST, Weiss DI, Choi AW, Hakimian J, Lu J, Ochoa MT, Bloom BR, Lanier LL, Stenger S, Modlin RL. Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria. Science Immunology. 3. PMID 30171080 DOI: 10.1126/Sciimmunol.Aat7668  0.52
2018 Kim EW, Teles RMB, Haile S, Liu PT, Modlin RL. Vitamin D status contributes to the antimicrobial activity of macrophages against Mycobacterium leprae. Plos Neglected Tropical Diseases. 12: e0006608. PMID 29965969 DOI: 10.1371/Journal.Pntd.0006608  0.76
2017 Wang L, Liu SY, Chen HW, Xu J, Chapon M, Zhang T, Zhou F, Wang YE, Quanquin N, Wang G, Tian X, He Z, Liu L, Yu W, Sanchez DJ, ... ... Modlin R, et al. Generation of a Live Attenuated Influenza Vaccine that Elicits Broad Protection in Mice and Ferrets. Cell Host & Microbe. 21: 334-343. PMID 28279345 DOI: 10.1016/J.Chom.2017.02.007  0.56
2016 Inkeles MS, Teles RM, Pouldar D, Andrade PR, Madigan CA, Lopez D, Ambrose M, Noursadeghi M, Sarno EN, Rea TH, Ochoa MT, Iruela-Arispe ML, Swindell WR, Ottenhoff TH, Geluk A, ... ... Modlin RL, et al. Cell-type deconvolution with immune pathways identifies gene networks of host defense and immunopathology in leprosy. Jci Insight. 1: e88843. PMID 27699251 DOI: 10.1172/Jci.Insight.88843  0.4
2016 Yu Y, Champer J, Agak GW, Kao S, Modlin RL, Kim J. Different Propionibacterium acnes phylotypes induce distinct immune responses and express unique surface and secreted proteomes. The Journal of Investigative Dermatology. PMID 27377696 DOI: 10.1016/J.Jid.2016.06.615  0.44
2016 Realegeno S, Kelly-Scumpia KM, Dang AT, Lu J, Teles R, Liu PT, Schenk M, Lee EY, Schmidt NW, Wong GC, Sarno EN, Rea TH, Ochoa MT, Pellegrini M, Modlin RL. S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages. Plos Pathogens. 12: e1005705. PMID 27355424 DOI: 10.1371/Journal.Ppat.1005705  0.8
2016 Ochoa MT, Vaccaro S, Jerskey R, Mora H, Peng D, Modlin RL. Thomas Herald Rea, MD (1929-2016). Leprosy Review. 87: 130-1. PMID 27255071  0.4
2016 Steiger J, Stephan A, Inkeles MS, Realegeno S, Bruns H, Kröll P, de Castro Kroner J, Sommer A, Batinica M, Pitzler L, Kalscheuer R, Hartmann P, Plum G, Stenger S, Pellegrini M, ... ... Modlin RL, et al. Imatinib Triggers Phagolysosome Acidification and Antimicrobial Activity against Mycobacterium bovis Bacille Calmette-Guérin in Glucocorticoid-Treated Human Macrophages. Journal of Immunology (Baltimore, Md. : 1950). PMID 27233968 DOI: 10.4049/Jimmunol.1502407  0.52
2016 Busch M, Herzmann C, Kallert S, Zimmermann A, Höfer C, Mayer D, Zenk SF, Muche R, Lange C, Bloom BR, Modlin RL, Stenger S. Lipoarabinomannan-responsive Polycytotoxic T Cells are Associated With Protection in Human Tuberculosis. American Journal of Respiratory and Critical Care Medicine. PMID 26882070 DOI: 10.1164/Rccm.201509-1746Oc  0.52
2015 Meller S, Di Domizio J, Voo KS, Friedrich HC, Chamilos G, Ganguly D, Conrad C, Gregorio J, Le Roy D, Roger T, Ladbury JE, Homey B, Watowich S, Modlin RL, Kontoyiannis DP, et al. TH17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26. Nature Immunology. 16: 970-9. PMID 26168081 DOI: 10.1038/Ni.3211  0.8
2015 Teles RM, Kelly-Scumpia KM, Sarno EN, Rea TH, Ochoa MT, Cheng G, Modlin RL. IL-27 Suppresses Antimicrobial Activity in Human Leprosy. The Journal of Investigative Dermatology. 135: 2410-7. PMID 26030183 DOI: 10.1038/Jid.2015.195  0.56
2015 Cappuccio A, Zollinger R, Schenk M, Walczak A, Servant N, Barillot E, Hupé P, Modlin RL, Soumelis V. Combinatorial code governing cellular responses to complex stimuli. Nature Communications. 6: 6847. PMID 25896517 DOI: 10.1038/Ncomms7847  0.8
2015 Bourgeois EA, Subramaniam S, Cheng TY, De Jong A, Layre E, Ly D, Salimi M, Legaspi A, Modlin RL, Salio M, Cerundolo V, Moody DB, Ogg G. Bee venom processes human skin lipids for presentation by CD1a. The Journal of Experimental Medicine. 212: 149-63. PMID 25584012 DOI: 10.1084/Jem.20141505  0.8
2015 Kim HJ, Brennan PJ, Heaslip D, Udey MC, Modlin RL, Belisle JT. Carbohydrate-dependent binding of langerin to SodC, a cell wall glycoprotein of Mycobacterium leprae. Journal of Bacteriology. 197: 615-25. PMID 25422308 DOI: 10.1128/Jb.02080-14  0.8
2015 Inkeles MS, Scumpia PO, Swindell WR, Lopez D, Teles RM, Graeber TG, Meller S, Homey B, Elder JT, Gilliet M, Modlin RL, Pellegrini M. Comparison of molecular signatures from multiple skin diseases identifies mechanisms of immunopathogenesis. The Journal of Investigative Dermatology. 135: 151-9. PMID 25111617 DOI: 10.1038/Jid.2014.352  0.8
2015 Teles RMB, Kelly-Scumpia KM, Sarno EN, Rea TH, Ochoa MT, Cheng G, Modlin RL. IL-27 Suppresses Antimicrobial Activity in Human Leprosy Journal of Investigative Dermatology. DOI: 10.1038/jid.2015.195  0.56
2014 Montoya D, Inkeles MS, Liu PT, Realegeno S, Teles RM, Vaidya P, Munoz MA, Schenk M, Swindell WR, Chun R, Zavala K, Hewison M, Adams JS, Horvath S, Pellegrini M, ... ... Modlin RL, et al. IL-32 is a molecular marker of a host defense network in human tuberculosis. Science Translational Medicine. 6: 250ra114. PMID 25143364 DOI: 10.1126/Scitranslmed.3009546  0.8
2014 Chun RF, Liu PT, Modlin RL, Adams JS, Hewison M. Impact of vitamin D on immune function: lessons learned from genome-wide analysis. Frontiers in Physiology. 5: 151. PMID 24795646 DOI: 10.3389/Fphys.2014.00151  0.8
2014 Schenk M, Fabri M, Krutzik SR, Lee DJ, Vu DM, Sieling PA, Montoya D, Liu PT, Modlin RL. Interleukin-1β triggers the differentiation of macrophages with enhanced capacity to present mycobacterial antigen to T cells. Immunology. 141: 174-80. PMID 24032597 DOI: 10.1111/Imm.12167  0.8
2013 Modlin RL, Bloom BR. TB or not TB: that is no longer the question. Science Translational Medicine. 5: 213sr6. PMID 24285487 DOI: 10.1126/Scitranslmed.3007402  0.8
2013 Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, ... ... Modlin RL, et al. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science (New York, N.Y.). 339: 1448-53. PMID 23449998 DOI: 10.1126/Science.1233665  0.8
2013 Fitz-Gibbon S, Tomida S, Chiu BH, Nguyen L, Du C, Liu M, Elashoff D, Erfe MC, Loncaric A, Kim J, Modlin RL, Miller JF, Sodergren E, Craft N, Weinstock GM, et al. Propionibacterium acnes strain populations in the human skin microbiome associated with acne. The Journal of Investigative Dermatology. 133: 2152-60. PMID 23337890 DOI: 10.1038/Jid.2013.21  0.8
2013 Klug-Micu GM, Stenger S, Sommer A, Liu PT, Krutzik SR, Modlin RL, Fabri M. CD40 ligand and interferon-γ induce an antimicrobial response against Mycobacterium tuberculosis in human monocytes. Immunology. 139: 121-8. PMID 23289765 DOI: 10.1111/Imm.12062  0.8
2013 Chung AW, Sieling PA, Schenk M, Teles RM, Krutzik SR, Hsu DK, Liu FT, Sarno EN, Rea TH, Stenger S, Modlin RL, Lee DJ. Galectin-3 regulates the innate immune response of human monocytes. The Journal of Infectious Diseases. 207: 947-56. PMID 23255567 DOI: 10.1093/Infdis/Jis920  0.8
2013 Friedman AJ, Phan J, Schairer DO, Champer J, Qin M, Pirouz A, Blecher-Paz K, Oren A, Liu PT, Modlin RL, Kim J. Antimicrobial and anti-inflammatory activity of chitosan-alginate nanoparticles: a targeted therapy for cutaneous pathogens. The Journal of Investigative Dermatology. 133: 1231-9. PMID 23190896 DOI: 10.1038/Jid.2012.399  0.8
2013 Chiu MW, Modlin RL. Program spotlight: The UCLA division of dermatology residency training program Journal of Drugs in Dermatology. 12: 109-110.  0.8
2012 Parvatiyar K, Zhang Z, Teles RM, Ouyang S, Jiang Y, Iyer SS, Zaver SA, Schenk M, Zeng S, Zhong W, Liu ZJ, Modlin RL, Liu YJ, Cheng G. The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nature Immunology. 13: 1155-61. PMID 23142775 DOI: 10.1038/Ni.2460  0.8
2012 Jacobs-Sera D, Marinelli LJ, Bowman C, Broussard GW, Guerrero Bustamante C, Boyle MM, Petrova ZO, Dedrick RM, Pope WH, Modlin RL, Hendrix RW, Hatfull GF. On the nature of mycobacteriophage diversity and host preference. Virology. 434: 187-201. PMID 23084079 DOI: 10.1016/J.Virol.2012.09.026  0.8
2012 Marinelli LJ, Fitz-Gibbon S, Hayes C, Bowman C, Inkeles M, Loncaric A, Russell DA, Jacobs-Sera D, Cokus S, Pellegrini M, Kim J, Miller JF, Hatfull GF, Modlin RL. Propionibacterium acnes bacteriophages display limited genetic diversity and broad killing activity against bacterial skin isolates. Mbio. 3. PMID 23015740 DOI: 10.1128/Mbio.00279-12  0.8
2012 Bruns H, Stegelmann F, Fabri M, Döhner K, van Zandbergen G, Wagner M, Skinner M, Modlin RL, Stenger S. Abelson tyrosine kinase controls phagosomal acidification required for killing of Mycobacterium tuberculosis in human macrophages. Journal of Immunology (Baltimore, Md. : 1950). 189: 4069-78. PMID 22988030 DOI: 10.4049/Jimmunol.1201538  0.8
2012 Chamilos G, Gregorio J, Meller S, Lande R, Kontoyiannis DP, Modlin RL, Gilliet M. Cytosolic sensing of extracellular self-DNA transported into monocytes by the antimicrobial peptide LL37. Blood. 120: 3699-707. PMID 22927244 DOI: 10.1182/Blood-2012-01-401364  0.8
2012 Torrelles JB, Sieling PA, Zhang N, Keen MA, McNeil MR, Belisle JT, Modlin RL, Brennan PJ, Chatterjee D. Isolation of a distinct Mycobacterium tuberculosis mannose-capped lipoarabinomannan isoform responsible for recognition by CD1b-restricted T cells. Glycobiology. 22: 1118-27. PMID 22534567 DOI: 10.1093/Glycob/Cws078  0.8
2012 Schenk M, Krutzik SR, Sieling PA, Lee DJ, Teles RM, Ochoa MT, Komisopoulou E, Sarno EN, Rea TH, Graeber TG, Kim S, Cheng G, Modlin RL. NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nature Medicine. 18: 555-63. PMID 22447076 DOI: 10.1038/Nm.2650  0.8
2012 Bickers DR, Modlin RL. A review of the Journal of Investigative Dermatology's most cited publications over the past 25 years and the use of developing bibliometric methodologies to assess journal quality. The Journal of Investigative Dermatology. 132: 1050-60. PMID 22330274 DOI: 10.1038/Jid.2011.391  0.8
2012 Hou W, Gibbs JS, Lu X, Brooke CB, Roy D, Modlin RL, Bennink JR, Yewdell JW. Viral infection triggers rapid differentiation of human blood monocytes into dendritic cells. Blood. 119: 3128-31. PMID 22310910 DOI: 10.1182/Blood-2011-09-379479  0.8
2012 Liu PT, Wheelwright M, Teles R, Komisopoulou E, Edfeldt K, Ferguson B, Mehta MD, Vazirnia A, Rea TH, Sarno EN, Graeber TG, Modlin RL. MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy. Nature Medicine. 18: 267-73. PMID 22286305 DOI: 10.1038/Nm.2584  0.76
2012 Modlin RL. Innate immunity: ignored for decades, but not forgotten. The Journal of Investigative Dermatology. 132: 882-6. PMID 22158552 DOI: 10.1038/Jid.2011.373  0.8
2011 Realegeno S, Modlin RL. Shedding light on the vitamin D-tuberculosis-HIV connection. Proceedings of the National Academy of Sciences of the United States of America. 108: 18861-2. PMID 22084116 DOI: 10.1073/Pnas.1116513108  0.8
2011 Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, Realegeno S, Lee HM, Krutzik SR, Schenk M, Sieling PA, Teles R, Montoya D, Iyer SS, Bruns H, Lewinsohn DM, ... ... Modlin RL, et al. Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Science Translational Medicine. 3: 104ra102. PMID 21998409 DOI: 10.1126/Scitranslmed.3003045  0.8
2011 Torrelles JB, Sieling PA, Arcos J, Knaup R, Bartling C, Rajaram MV, Stenger S, Modlin RL, Schlesinger LS. Structural differences in lipomannans from pathogenic and nonpathogenic mycobacteria that impact CD1b-restricted T cell responses. The Journal of Biological Chemistry. 286: 35438-46. PMID 21859718 DOI: 10.1074/Jbc.M111.232587  0.8
2011 Walker VP, Zhang X, Rastegar I, Liu PT, Hollis BW, Adams JS, Modlin RL. Cord blood vitamin D status impacts innate immune responses. The Journal of Clinical Endocrinology and Metabolism. 96: 1835-43. PMID 21470993 DOI: 10.1210/Jc.2010-1559  0.8
2011 Cruz D, Wang Z, Kibbie J, Modlin R, Kwon O. Diversity through phosphine catalysis identifies octahydro-1,6-naphthyridin-4-ones as activators of endothelium-driven immunity. Proceedings of the National Academy of Sciences of the United States of America. 108: 6769-74. PMID 21383121 DOI: 10.1073/Pnas.1015254108  0.8
2011 Cho JS, Zussman J, Donegan NP, Ramos RI, Garcia NC, Uslan DZ, Iwakura Y, Simon SI, Cheung AL, Modlin RL, Kim J, Miller LS. Noninvasive in vivo imaging to evaluate immune responses and antimicrobial therapy against Staphylococcus aureus and USA300 MRSA skin infections. The Journal of Investigative Dermatology. 131: 907-15. PMID 21191403 DOI: 10.1038/Jid.2010.417  0.44
2011 Glimcher LH, Martinon F, Modlin RL. Editorial overview. Current Opinion in Immunology. 23: 1-2. PMID 21185707 DOI: 10.1016/j.coi.2010.12.001  0.8
2011 Fabri M, Realegeno SE, Jo EK, Modlin RL. Role of autophagy in the host response to microbial infection and potential for therapy. Current Opinion in Immunology. 23: 65-70. PMID 21071195 DOI: 10.1016/J.Coi.2010.10.010  0.8
2010 Edfeldt K, Liu PT, Chun R, Fabri M, Schenk M, Wheelwright M, Keegan C, Krutzik SR, Adams JS, Hewison M, Modlin RL. T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism. Proceedings of the National Academy of Sciences of the United States of America. 107: 22593-8. PMID 21149724 DOI: 10.1073/Pnas.1011624108  0.8
2010 Teles RM, Krutzik SR, Ochoa MT, Oliveira RB, Sarno EN, Modlin RL. Interleukin-4 regulates the expression of CD209 and subsequent uptake of Mycobacterium leprae by Schwann cells in human leprosy. Infection and Immunity. 78: 4634-43. PMID 20713631 DOI: 10.1128/Iai.00454-10  0.8
2010 Ochoa MT, Teles R, Haas BE, Zaghi D, Li H, Sarno EN, Rea TH, Modlin RL, Lee DJ. A role for interleukin-5 in promoting increased immunoglobulin M at the site of disease in leprosy. Immunology. 131: 405-14. PMID 20561085 DOI: 10.1111/J.1365-2567.2010.03314.X  0.8
2010 Shin DM, Yuk JM, Lee HM, Lee SH, Son JW, Harding CV, Kim JM, Modlin RL, Jo EK. Mycobacterial lipoprotein activates autophagy via TLR2/1/CD14 and a functional vitamin D receptor signalling. Cellular Microbiology. 12: 1648-65. PMID 20560977 DOI: 10.1111/J.1462-5822.2010.01497.X  0.8
2010 Montoya D, Modlin RL. Learning from leprosy: insight into the human innate immune response. Advances in Immunology. 105: 1-24. PMID 20510728 DOI: 10.1016/S0065-2776(10)05001-7  0.8
2010 Chun RF, Lauridsen AL, Suon L, Zella LA, Pike JW, Modlin RL, Martineau AR, Wilkinson RJ, Adams J, Hewison M. Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D. The Journal of Clinical Endocrinology and Metabolism. 95: 3368-76. PMID 20427486 DOI: 10.1210/Jc.2010-0195  0.32
2010 Cho JS, Pietras EM, Garcia NC, Ramos RI, Farzam DM, Monroe HR, Magorien JE, Blauvelt A, Kolls JK, Cheung AL, Cheng G, Modlin RL, Miller LS. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. The Journal of Clinical Investigation. 120: 1762-73. PMID 20364087 DOI: 10.1172/Jci40891  0.8
2010 Lee DJ, Li H, Ochoa MT, Tanaka M, Carbone RJ, Damoiseaux R, Burdick A, Sarno EN, Rea TH, Modlin RL. Integrated pathways for neutrophil recruitment and inflammation in leprosy. The Journal of Infectious Diseases. 201: 558-69. PMID 20070238 DOI: 10.1086/650318  0.8
2010 Modlin RL. The innate immune response in leprosy. Current Opinion in Immunology. 22: 48-54. PMID 20060279 DOI: 10.1016/J.Coi.2009.12.001  0.8
2010 French N, Modlin RL. Bacterial and mycobacterial infections Therapy of Skin Diseases: a Worldwide Perspective On Therapeutic Approaches and Their Molecular Basis. 129-148. DOI: 10.1007/978-3-540-78814-0_14  0.8
2009 Schenk M, Belisle JT, Modlin RL. TLR2 looks at lipoproteins. Immunity. 31: 847-9. PMID 20064441 DOI: 10.1016/J.Immuni.2009.11.008  0.8
2009 Montoya D, Cruz D, Teles RM, Lee DJ, Ochoa MT, Krutzik SR, Chun R, Schenk M, Zhang X, Ferguson BG, Burdick AE, Sarno EN, Rea TH, Hewison M, Adams JS, ... ... Modlin RL, et al. Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host & Microbe. 6: 343-53. PMID 19837374 DOI: 10.1016/J.Chom.2009.09.002  0.8
2009 Fabri M, Modlin RL. A vitamin for autophagy. Cell Host & Microbe. 6: 201-3. PMID 19748462 DOI: 10.1016/J.Chom.2009.08.008  0.8
2009 Modlin RL, Brenner MB. T cell responses in microbial infection. Current Opinion in Immunology. 21: 365-6. PMID 19643590 DOI: 10.1016/J.Coi.2009.07.007  0.8
2009 Tanaka M, Krutzik SR, Sieling PA, Lee DJ, Rea TH, Modlin RL. Activation of Fc gamma RI on monocytes triggers differentiation into immature dendritic cells that induce autoreactive T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 183: 2349-55. PMID 19635920 DOI: 10.4049/Jimmunol.0801683  0.8
2009 Shin OS, Miller LS, Modlin RL, Akira S, Uematsu S, Hu LT. Downstream signals for MyD88-mediated phagocytosis of Borrelia burgdorferi can be initiated by TRIF and are dependent on PI3K. Journal of Immunology (Baltimore, Md. : 1950). 183: 491-8. PMID 19542460 DOI: 10.4049/Jimmunol.0900724  0.8
2009 Liu PT, Schenk M, Walker VP, Dempsey PW, Kanchanapoomi M, Wheelwright M, Vazirnia A, Zhang X, Steinmeyer A, Zügel U, Hollis BW, Cheng G, Modlin RL. Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses. Plos One. 4: e5810. PMID 19503839 DOI: 10.1371/Journal.Pone.0005810  0.76
2009 Bruns H, Meinken C, Schauenberg P, Härter G, Kern P, Modlin RL, Antoni C, Stenger S. Anti-TNF immunotherapy reduces CD8+ T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans. The Journal of Clinical Investigation. 119: 1167-77. PMID 19381021 DOI: 10.1172/Jci38482  0.8
2009 Adams JS, Ren S, Liu PT, Chun RF, Lagishetty V, Gombart AF, Borregaard N, Modlin RL, Hewison M. Vitamin d-directed rheostatic regulation of monocyte antibacterial responses. Journal of Immunology (Baltimore, Md. : 1950). 182: 4289-95. PMID 19299728 DOI: 10.4049/Jimmunol.0803736  0.8
2009 Walker VP, Modlin RL. The vitamin D connection to pediatric infections and immune function. Pediatric Research. 65: 106R-113R. PMID 19190532 DOI: 10.1203/Pdr.0B013E31819Dba91  0.8
2008 Lee DJ, Modlin RL. DNA transportation authority. Nature Medicine. 14: 1319-20. PMID 19057557 DOI: 10.1038/Nm1208-1319  0.8
2008 Krutzik SR, Hewison M, Liu PT, Robles JA, Stenger S, Adams JS, Modlin RL. IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway. Journal of Immunology (Baltimore, Md. : 1950). 181: 7115-20. PMID 18981132 DOI: 10.4049/Jimmunol.181.10.7115  0.8
2008 Cruz D, Watson AD, Miller CS, Montoya D, Ochoa MT, Sieling PA, Gutierrez MA, Navab M, Reddy ST, Witztum JL, Fogelman AM, Rea TH, Eisenberg D, Berliner J, Modlin RL. Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy. The Journal of Clinical Investigation. 118: 2917-28. PMID 18636118 DOI: 10.1172/Jci34189  0.8
2008 Liu PT, Modlin RL. Human macrophage host defense against Mycobacterium tuberculosis. Current Opinion in Immunology. 20: 371-6. PMID 18602003 DOI: 10.1016/J.Coi.2008.05.014  0.8
2008 Sieling PA, Hill PJ, Dobos KM, Brookman K, Kuhlman AM, Fabri M, Krutzik SR, Rea TH, Heaslip DG, Belisle JT, Modlin RL. Conserved mycobacterial lipoglycoproteins activate TLR2 but also require glycosylation for MHC class II-restricted T cell activation. Journal of Immunology (Baltimore, Md. : 1950). 180: 5833-42. PMID 18424702 DOI: 10.4049/Jimmunol.180.9.5833  0.8
2008 Ochoa MT, Loncaric A, Krutzik SR, Becker TC, Modlin RL. "Dermal dendritic cells" comprise two distinct populations: CD1+ dendritic cells and CD209+ macrophages. The Journal of Investigative Dermatology. 128: 2225-31. PMID 18337829 DOI: 10.1038/Jid.2008.56  0.8
2008 Tanaka M, Krutzik SR, Sieling PA, Rea TH, Modlin RL. Fc{gamma} receptor activation triggers monocytes to differentiate into immature dendritic cells that promote autologous T cell response The Faseb Journal. 22: 468-468. DOI: 10.1096/Fasebj.22.2_Supplement.468  0.72
2007 Adams JS, Chen H, Chun R, Ren S, Wu S, Gacad M, Nguyen L, Ride J, Liu P, Modlin R, Hewison M. Substrate and enzyme trafficking as a means of regulating 1,25-dihydroxyvitamin D synthesis and action: The human innate immune response Journal of Bone and Mineral Research. 22: V20-V24. PMID 18290716 DOI: 10.1359/Jbmr.07S214  0.8
2007 Bhandarkar SS, Cohen C, Kuruvila M, Rea TH, Mackelfresh JB, Lee DJ, Modlin RL, Arbiser JL. Angiogenesis in cutaneous lesions of leprosy: implications for treatment. Archives of Dermatology. 143: 1527-9. PMID 18087002 DOI: 10.1001/Archderm.143.12.1527  0.8
2007 Lee DJ, Sieling PA, Ochoa MT, Krutzik SR, Guo B, Hernandez M, Rea TH, Cheng G, Colonna M, Modlin RL. LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 8128-36. PMID 18056355 DOI: 10.4049/Jimmunol.179.12.8128  0.8
2007 Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, O'Connell RM, Iwakura Y, Cheung AL, Cheng G, Modlin RL. Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo. Journal of Immunology (Baltimore, Md. : 1950). 179: 6933-42. PMID 17982084 DOI: 10.4049/Jimmunol.179.10.6933  0.8
2007 Liu PT, Stenger S, Tang DH, Modlin RL. Cutting edge: vitamin D-mediated human antimicrobial activity against Mycobacterium tuberculosis is dependent on the induction of cathelicidin. Journal of Immunology (Baltimore, Md. : 1950). 179: 2060-3. PMID 17675463 DOI: 10.4049/Jimmunol.179.4.2060  0.8
2007 Adams JS, Liu PT, Chun R, Modlin RL, Hewison M. Vitamin D in defense of the human immune response. Annals of the New York Academy of Sciences. 1117: 94-105. PMID 17656563 DOI: 10.1196/Annals.1402.036  0.8
2007 Niazi KR, Ochoa MT, Sieling PA, Rooke NE, Peter AK, Mollahan P, Dickey M, Rabizadeh S, Rea TH, Modlin RL. Activation of human CD4+ T cells by targeting MHC class II epitopes to endosomal compartments using human CD1 tail sequences. Immunology. 122: 522-31. PMID 17635609 DOI: 10.1111/J.1365-2567.2007.02666.X  0.8
2007 Miller LS, Modlin RL. Toll-like receptors in the skin. Seminars in Immunopathology. 29: 15-26. PMID 17621951 DOI: 10.1007/S00281-007-0061-8  0.8
2007 Hewison M, Burke F, Evans KN, Lammas DA, Sansom DM, Liu P, Modlin RL, Adams JS. Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease. The Journal of Steroid Biochemistry and Molecular Biology. 103: 316-21. PMID 17368179 DOI: 10.1016/J.Jsbmb.2006.12.078  0.8
2007 Sieling PA, Legaspi A, Ochoa MT, Rea TH, Modlin RL. Regulation of human T-cell homing receptor expression in cutaneous bacterial infection. Immunology. 120: 518-25. PMID 17343614 DOI: 10.1111/J.1365-2567.2006.02528.X  0.8
2007 Schauber J, Dorschner RA, Coda AB, Büchau AS, Liu PT, Kiken D, Helfrich YR, Kang S, Elalieh HZ, Steinmeyer A, Zügel U, Bikle DD, Modlin RL, Gallo RL. Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. The Journal of Clinical Investigation. 117: 803-11. PMID 17290304 DOI: 10.1172/Jci30142  0.76
2007 Liu PT, Krutzik SR, Modlin RL. Therapeutic implications of the TLR and VDR partnership. Trends in Molecular Medicine. 13: 117-24. PMID 17276732 DOI: 10.1016/J.Molmed.2007.01.006  0.8
2007 Winau F, Hegasy G, Weiskirchen R, Weber S, Cassan C, Sieling PA, Modlin RL, Liblau RS, Gressner AM, Kaufmann SH. Ito cells are liver-resident antigen-presenting cells for activating T cell responses. Immunity. 26: 117-29. PMID 17239632 DOI: 10.1016/J.Immuni.2006.11.011  0.56
2007 Miller LS, Modlin RL. Human keratinocyte Toll-like receptors promote distinct immune responses. The Journal of Investigative Dermatology. 127: 262-3. PMID 17228303 DOI: 10.1038/Sj.Jid.5700559  0.8
2007 Sabet S, Ochoa MT, Sieling PA, Rea TH, Modlin RL. Functional characterization of a T-cell receptor BV6+ T-cell clone derived from a leprosy lesion. Immunology. 120: 354-61. PMID 17140401 DOI: 10.1111/J.1365-2567.2006.02510.X  0.8
2006 Chow EK, Castrillo A, Shahangian A, Pei L, O'Connell RM, Modlin RL, Tontonoz P, Cheng G. A role for IRF3-dependent RXRalpha repression in hepatotoxicity associated with viral infections. The Journal of Experimental Medicine. 203: 2589-602. PMID 17074929 DOI: 10.1084/Jem.20060929  0.8
2006 Im JS, Tapinos N, Chae GT, Illarionov PA, Besra GS, DeVries GH, Modlin RL, Sieling PA, Rambukkana A, Porcelli SA. Expression of CD1d molecules by human schwann cells and potential interactions with immunoregulatory invariant NK T cells. Journal of Immunology (Baltimore, Md. : 1950). 177: 5226-35. PMID 17015708 DOI: 10.4049/Jimmunol.177.8.5226  0.8
2006 Tan BH, Meinken C, Bastian M, Bruns H, Legaspi A, Ochoa MT, Krutzik SR, Bloom BR, Ganz T, Modlin RL, Stenger S. Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens. Journal of Immunology (Baltimore, Md. : 1950). 177: 1864-71. PMID 16849498 DOI: 10.4049/Jimmunol.177.3.1864  0.8
2006 Renn CN, Sanchez DJ, Ochoa MT, Legaspi AJ, Oh CK, Liu PT, Krutzik SR, Sieling PA, Cheng G, Modlin RL. TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response. Journal of Immunology (Baltimore, Md. : 1950). 177: 298-305. PMID 16785525 DOI: 10.4049/Jimmunol.177.1.298  0.8
2006 Hornell TM, Burster T, Jahnsen FL, Pashine A, Ochoa MT, Harding JJ, Macaubas C, Lee AW, Modlin RL, Mellins ED. Human dendritic cell expression of HLA-DO is subset specific and regulated by maturation. Journal of Immunology (Baltimore, Md. : 1950). 176: 3536-47. PMID 16517722 DOI: 10.4049/Jimmunol.176.6.3536  0.4
2006 Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, Ochoa MT, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zügel U, ... ... Modlin RL, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science (New York, N.Y.). 311: 1770-3. PMID 16497887 DOI: 10.1126/Science.1123933  0.8
2006 Miller LS, O'Connell RM, Gutierrez MA, Pietras EM, Shahangian A, Gross CE, Thirumala A, Cheung AL, Cheng G, Modlin RL. MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus. Immunity. 24: 79-91. PMID 16413925 DOI: 10.1016/J.Immuni.2005.11.011  0.8
2006 Liu P, Adams JS, Modlin RL. Response [7] Science. 312: 1874-1875. DOI: 10.1016/j.corsci.2005.07.011  0.8
2005 Stegelmann F, Bastian M, Swoboda K, Bhat R, Kiessler V, Krensky AM, Roellinghoff M, Modlin RL, Stenger S. Coordinate expression of CC chemokine ligand 5, granulysin, and perforin in CD8+ T cells provides a host defense mechanism against Mycobacterium tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 175: 7474-83. PMID 16301655 DOI: 10.4049/Jimmunol.175.11.7474  0.52
2005 McInturff JE, Wang SJ, Machleidt T, Lin TR, Oren A, Hertz CJ, Krutzik SR, Hart S, Zeh K, Anderson DH, Gallo RL, Modlin RL, Kim J. Granulysin-derived peptides demonstrate antimicrobial and anti-inflammatory effects against Propionibacterium acnes. The Journal of Investigative Dermatology. 125: 256-63. PMID 16098035 DOI: 10.1111/J.0022-202X.2005.23805.X  0.8
2005 Modlin RL, Sieling PA. Immunology. Now presenting: gammadelta T cells. Science (New York, N.Y.). 309: 252-3. PMID 16002604 DOI: 10.1126/Science.1115264  0.8
2005 McInturff JE, Modlin RL, Kim J. The role of toll-like receptors in the pathogenesis and treatment of dermatological disease. The Journal of Investigative Dermatology. 125: 1-8. PMID 15982296 DOI: 10.1111/J.0022-202X.2004.23459.X  0.8
2005 Krutzik SR, Tan B, Li H, Ochoa MT, Liu PT, Sharfstein SE, Graeber TG, Sieling PA, Liu YJ, Rea TH, Bloom BR, Modlin RL. TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells. Nature Medicine. 11: 653-60. PMID 15880118 DOI: 10.1038/Nm1246  0.8
2005 Miller LS, Sørensen OE, Liu PT, Jalian HR, Eshtiaghpour D, Behmanesh BE, Chung W, Starner TD, Kim J, Sieling PA, Ganz T, Modlin RL. TGF-alpha regulates TLR expression and function on epidermal keratinocytes. Journal of Immunology (Baltimore, Md. : 1950). 174: 6137-43. PMID 15879109 DOI: 10.4049/Jimmunol.174.10.6137  0.8
2005 Sieling PA, Torrelles JB, Stenger S, Chung W, Burdick AE, Rea TH, Brennan PJ, Belisle JT, Porcelli SA, Modlin RL. The human CD1-restricted T cell repertoire is limited to cross-reactive antigens: implications for host responses against immunologically related pathogens. Journal of Immunology (Baltimore, Md. : 1950). 174: 2637-44. PMID 15728470 DOI: 10.4049/Jimmunol.174.5.2637  0.8
2005 Liu PT, Krutzik SR, Kim J, Modlin RL. Cutting edge: all-trans retinoic acid down-regulates TLR2 expression and function. Journal of Immunology (Baltimore, Md. : 1950). 174: 2467-70. PMID 15728448 DOI: 10.4049/Jimmunol.174.5.2467  0.8
2005 Lee DJ, Modlin RL. Breaking tolerance--another piece added to the vitiligo puzzle. The Journal of Investigative Dermatology. 124: xiii-xv. PMID 15654945 DOI: 10.1111/J.0022-202X.2004.23553.X  0.8
2004 Modlin RL, Cheng G. From plankton to pathogen recognition. Nature Medicine. 10: 1173-4. PMID 15516915 DOI: 10.1038/Nm1104-1173  0.8
2004 Torrelles JB, Khoo KH, Sieling PA, Modlin RL, Zhang N, Marques AM, Treumann A, Rithner CD, Brennan PJ, Chatterjee D. Truncated structural variants of lipoarabinomannan in Mycobacterium leprae and an ethambutol-resistant strain of Mycobacterium tuberculosis. The Journal of Biological Chemistry. 279: 41227-39. PMID 15263002 DOI: 10.1074/Jbc.M405180200  0.56
2004 Hunger RE, Sieling PA, Ochoa MT, Sugaya M, Burdick AE, Rea TH, Brennan PJ, Belisle JT, Blauvelt A, Porcelli SA, Modlin RL. Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells. The Journal of Clinical Investigation. 113: 701-8. PMID 14991068 DOI: 10.1172/Jci19655  0.8
2004 Krutzik SR, Modlin RL. The role of Toll-like receptors in combating mycobacteria. Seminars in Immunology. 16: 35-41. PMID 14751762 DOI: 10.1016/J.Smim.2003.10.005  0.8
2004 Winau F, Schwierzeck V, Hurwitz R, Remmel N, Sieling PA, Modlin RL, Porcelli SA, Brinkmann V, Sugita M, Sandhoff K, Kaufmann SH, Schaible UE. Saposin C is required for lipid presentation by human CD1b. Nature Immunology. 5: 169-74. PMID 14716313 DOI: 10.1038/Ni1035  0.56
2004 Doyle SE, O'Connell RM, Miranda GA, Vaidya SA, Chow EK, Liu PT, Suzuki S, Suzuki N, Modlin RL, Yeh WC, Lane TF, Cheng G. Toll-like receptors induce a phagocytic gene program through p38. The Journal of Experimental Medicine. 199: 81-90. PMID 14699082 DOI: 10.1084/Jem.20031237  0.8
2003 Hertz CJ, Wu Q, Porter EM, Zhang YJ, Weismüller KH, Godowski PJ, Ganz T, Randell SH, Modlin RL. Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2. Journal of Immunology (Baltimore, Md. : 1950). 171: 6820-6. PMID 14662888 DOI: 10.4049/Jimmunol.171.12.6820  0.8
2003 Bleharski JR, Li H, Meinken C, Graeber TG, Ochoa MT, Yamamura M, Burdick A, Sarno EN, Wagner M, Röllinghoff M, Rea TH, Colonna M, Stenger S, Bloom BR, Eisenberg D, ... Modlin RL, et al. Use of genetic profiling in leprosy to discriminate clinical forms of the disease. Science (New York, N.Y.). 301: 1527-30. PMID 12970564 DOI: 10.1126/Science.1087785  0.8
2003 Schaible UE, Winau F, Sieling PA, Fischer K, Collins HL, Hagens K, Modlin RL, Brinkmann V, Kaufmann SH. Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis. Nature Medicine. 9: 1039-46. PMID 12872166 DOI: 10.1038/Nm906  0.56
2003 Walton KA, Cole AL, Yeh M, Subbanagounder G, Krutzik SR, Modlin RL, Lucas RM, Nakai J, Smart EJ, Vora DK, Berliner JA. Specific phospholipid oxidation products inhibit ligand activation of toll-like receptors 4 and 2. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1197-203. PMID 12775576 DOI: 10.1161/01.Atv.0000079340.80744.B8  0.8
2003 Arora T, Liu B, He H, Kim J, Murphy TL, Murphy KM, Modlin RL, Shuai K. PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4. The Journal of Biological Chemistry. 278: 21327-30. PMID 12716907 DOI: 10.1074/Jbc.C300119200  0.8
2003 Krutzik SR, Ochoa MT, Sieling PA, Uematsu S, Ng YW, Legaspi A, Liu PT, Cole ST, Godowski PJ, Maeda Y, Sarno EN, Norgard MV, Brennan PJ, Akira S, Rea TH, ... Modlin RL, et al. Activation and regulation of Toll-like receptors 2 and 1 in human leprosy. Nature Medicine. 9: 525-32. PMID 12692544 DOI: 10.1038/Nm864  0.8
2003 Bleharski JR, Kiessler V, Buonsanti C, Sieling PA, Stenger S, Colonna M, Modlin RL. A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response. Journal of Immunology (Baltimore, Md. : 1950). 170: 3812-8. PMID 12646648 DOI: 10.4049/Jimmunol.170.7.3812  0.8
2003 Gansert JL, Kiessler V, Engele M, Wittke F, Röllinghoff M, Krensky AM, Porcelli SA, Modlin RL, Stenger S. Human NKT cells express granulysin and exhibit antimycobacterial activity. Journal of Immunology (Baltimore, Md. : 1950). 170: 3154-61. PMID 12626573 DOI: 10.4049/Jimmunol.170.6.3154  0.8
2003 Oliveira RB, Ochoa MT, Sieling PA, Rea TH, Rambukkana A, Sarno EN, Modlin RL. Expression of Toll-like receptor 2 on human Schwann cells: a mechanism of nerve damage in leprosy. Infection and Immunity. 71: 1427-33. PMID 12595460 DOI: 10.1128/Iai.71.3.1427-1433.2003  0.8
2003 Hertz CJ, Modlin RL. Role of toll-like receptors in response to bacterial infection. Contributions to Microbiology. 10: 149-63. PMID 12530325 DOI: 10.1159/000068135  0.8
2003 Ochoa MT, Legaspi AJ, Hatziris Z, Godowski PJ, Modlin RL, Sieling PA. Distribution of Toll-like receptor 1 and Toll-like receptor 2 in human lymphoid tissue. Immunology. 108: 10-5. PMID 12519297 DOI: 10.1046/J.1365-2567.2003.01563.X  0.8
2003 Sieling PA, Chung W, Duong BT, Godowski PJ, Modlin RL. Toll-like receptor 2 ligands as adjuvants for human Th1 responses. Journal of Immunology (Baltimore, Md. : 1950). 170: 194-200. PMID 12496400 DOI: 10.4049/Jimmunol.170.1.194  0.8
2003 Anderson DH, Sawaya MR, Cascio D, Ernst W, Modlin R, Krensky A, Eisenberg D. Granulysin crystal structure and a structure-derived lytic mechanism. Journal of Molecular Biology. 325: 355-65. PMID 12488100 DOI: 10.1016/S0022-2836(02)01234-2  0.8
2003 Modlin RL, Doherty P. Host-pathogen interactions: Host defense against microbial pathogens - The immune system's weapons of mass destruction Current Opinion in Immunology. 15: 393-395. DOI: 10.1016/S0952-7915(03)00082-7  0.8
2002 Doyle S, Vaidya S, O'Connell R, Dadgostar H, Dempsey P, Wu T, Rao G, Sun R, Haberland M, Modlin R, Cheng G. IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity. 17: 251-63. PMID 12354379 DOI: 10.1016/S1074-7613(02)00390-4  0.8
2002 Niazi KR, Porcelli SA, Modlin RL. The CD1b structure: antigen presentation adapts to a high-fat diet. Nature Immunology. 3: 703-4. PMID 12145652 DOI: 10.1038/Ni0802-703  0.8
2002 Kim J, Ochoa MT, Krutzik SR, Takeuchi O, Uematsu S, Legaspi AJ, Brightbill HD, Holland D, Cunliffe WJ, Akira S, Sieling PA, Godowski PJ, Modlin RL. Activation of toll-like receptor 2 in acne triggers inflammatory cytokine responses. Journal of Immunology (Baltimore, Md. : 1950). 169: 1535-41. PMID 12133981 DOI: 10.4049/Jimmunol.169.3.1535  0.8
2002 Stenger S, Modlin RL. Control of Mycobacterium tuberculosis through mammalian Toll-like receptors. Current Opinion in Immunology. 14: 452-7. PMID 12088679 DOI: 10.1016/S0952-7915(02)00355-2  0.8
2002 Modlin RL. Mammalian toll-like receptors. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. 88: 543-7; quiz 548-50, . PMID 12086359 DOI: 10.1016/S1081-1206(10)61883-2  0.8
2002 Takeuchi O, Sato S, Horiuchi T, Hoshino K, Takeda K, Dong Z, Modlin RL, Akira S. Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. Journal of Immunology (Baltimore, Md. : 1950). 169: 10-4. PMID 12077222 DOI: 10.4049/Jimmunol.169.1.10  0.8
2002 Sieling PA, Modlin RL. Toll-like receptors: mammalian "taste receptors" for a smorgasbord of microbial invaders. Current Opinion in Microbiology. 5: 70-5. PMID 11834372 DOI: 10.1016/S1369-5274(02)00288-6  0.8
2002 Modlin RL. Learning from leprosy: insights into contemporary immunology from an ancient disease. Skin Pharmacology and Applied Skin Physiology. 15: 1-6. PMID 11803252 DOI: 10.1159/000058177  0.8
2002 Brightbill HD, Modlin RL. 22 Activation of innate immune receptors by bacterial products Methods in Microbiology. 31: 397-418.  0.8
2001 Modlin RL, Bloom BR. Chips, infections, and national security [1] Science. 294: 1279. PMID 11702789 DOI: 10.1126/Science.294.5545.1279B  0.8
2001 Modlin RL, Bloom BR. Immunology: Chip shots - Will functional genomics get functional? Science. 294: 799-801. PMID 11679655 DOI: 10.1126/Science.1066314  0.8
2001 Modlin RL. Activation of toll-like receptors by microbial lipoproteins: Role in host defense Journal of Allergy and Clinical Immunology. 108. PMID 11586275 DOI: 10.1067/Mai.2001.118299  0.8
2001 Bleharski JR, Niazi KR, Sieling PA, Cheng G, Modlin RL. Signaling lymphocytic activation molecule is expressed on CD40 ligand-activated dendritic cells and directly augments production of inflammatory cytokines. Journal of Immunology (Baltimore, Md. : 1950). 167: 3174-81. PMID 11544303 DOI: 10.4049/Jimmunol.167.6.3174  0.8
2001 Kim J, Uyemura K, Van Dyke MK, Legaspi AJ, Rea TH, Shuai K, Modlin RL. A role for IL-12 receptor expression and signal transduction in host defense in leprosy. Journal of Immunology (Baltimore, Md. : 1950). 167: 779-86. PMID 11441083 DOI: 10.4049/Jimmunol.167.2.779  0.8
2001 Thoma-Uszynski S, Stenger S, Takeuchi O, Ochoa MT, Engele M, Sieling PA, Barnes PF, Röllinghoff M, Bölcskei PL, Wagner M, Akira S, Norgard MV, Belisle JT, Godowski PJ, Bloom BR, ... Modlin RL, et al. Induction of direct antimicrobial activity through mammalian toll-like receptors Science. 291: 1544-1547. PMID 11222859 DOI: 10.1126/Science.291.5508.1544  0.8
2001 Ochoa MT, Stenger S, Sieling PA, Thoma-Uszynski S, Sabet S, Cho S, Krensky AM, Rollinghoff M, Nunes Sarno E, Burdick AE, Rea TH, Modlin RL. T-cell release of granulysin contributes to host defense in leprosy. Nature Medicine. 7: 174-9. PMID 11175847 DOI: 10.1038/84620  0.8
2001 Niazi K, Chiu M, Mendoza R, Degano M, Khurana S, Moody D, Melián A, Wilson I, Kronenberg M, Porcelli S, Modlin R. The A' and F' pockets of human CD1b are both required for optimal presentation of lipid antigens to T cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 2562-70. PMID 11160317 DOI: 10.4049/Jimmunol.166.4.2562  0.8
2001 Hertz CJ, Kiertscher SM, Godowski PJ, Bouis DA, Norgard MV, Roth MD, Modlin RL. Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2 Journal of Immunology. 166: 2444-2450. PMID 11160304 DOI: 10.4049/Jimmunol.166.4.2444  0.8
2001 Krutzik SR, Sieling PA, Modlin RL. The role of Toll-like receptors in host defense against microbial infection. Current Opinion in Immunology. 13: 104-8. PMID 11154925 DOI: 10.1016/S0952-7915(00)00189-8  0.8
2000 Ochoa MT, Thoma-Uszynski S, Sieling PA, Sabet S, Cho S, Krensky AM, Burdick A, Rea TH, Modlin RL. Role of granulysin in immunity to leprosy. Leprosy Review. 71: S115; discussion S11. PMID 11201866  0.8
2000 Modlin RL. A toll for DNA vaccines Nature. 408: 659-660. PMID 11130055 DOI: 10.1038/35047207  0.8
2000 Ernst WA, Thoma-Uszynski S, Teitelbaum R, Ko C, Hanson DA, Clayberger C, Krensky AM, Leippe M, Bloom BR, Ganz T, Modlin RL. Granulysin, a T cell product, kills bacteria by altering membrane permeability. Journal of Immunology (Baltimore, Md. : 1950). 165: 7102-8. PMID 11120840 DOI: 10.4049/Jimmunol.165.12.7102  0.8
2000 Thoma-Uszynski S, Stenger S, Modlin RL. CTL-mediated killing of intracellular Mycobacterium tuberculosis is independent of target cell nuclear apoptosis Journal of Immunology. 165: 5773-5779. PMID 11067936 DOI: 10.4049/Jimmunol.165.10.5773  0.8
2000 Tan BH, Modlin RL. Drosophila, the savvy exterminator. Nature Immunology. 1: 361. PMID 11062488 DOI: 10.1038/80793  0.8
2000 Melián A, Watts GF, Shamshiev A, De Libero G, Clatworthy A, Vincent M, Brenner MB, Behar S, Niazi K, Modlin RL, Almo S, Ostrov D, Nathenson SG, Porcelli SA. Molecular recognition of human CD1b antigen complexes: evidence for a common pattern of interaction with alpha beta TCRs. Journal of Immunology (Baltimore, Md. : 1950). 165: 4494-504. PMID 11035089 DOI: 10.4049/Jimmunol.165.8.4494  0.36
2000 Thoma-Uszynski S, Kiertscher SM, Ochoa MT, Bouis DA, Norgard MV, Miyake K, Godowski PJ, Roth MD, Modlin RL. Activation of toll-like receptor 2 on human dendritic cells triggers induction of IL-12, but not IL-10. Journal of Immunology (Baltimore, Md. : 1950). 165: 3804-10. PMID 11034386 DOI: 10.4049/Jimmunol.165.7.3804  0.4
2000 Brightbill HD, Modlin RL. Toll-like receptors: molecular mechanisms of the mammalian immune response. Immunology. 101: 1-10. PMID 11012747 DOI: 10.1046/J.1365-2567.2000.00093.X  0.8
2000 Yamauchi PS, Bleharski JR, Uyemura K, Kim J, Sieling PA, Miller A, Brightbill H, Schlienger K, Rea TH, Modlin RL. A role for CD40-CD40 ligand interactions in the generation of type 1 cytokine responses in human leprosy. Journal of Immunology (Baltimore, Md. : 1950). 165: 1506-12. PMID 10903757 DOI: 10.4049/Jimmunol.165.3.1506  0.8
2000 Sieling PA, Ochoa MT, Jullien D, Leslie DS, Sabet S, Rosat JP, Burdick AE, Rea TH, Brenner MB, Porcelli SA, Modlin RL. Evidence for human CD4+ T cells in the CD1-restricted repertoire: derivation of mycobacteria-reactive T cells from leprosy lesions. Journal of Immunology (Baltimore, Md. : 1950). 164: 4790-6. PMID 10779786 DOI: 10.4049/Jimmunol.164.9.4790  0.8
2000 Thomas JA, Modlin RL, Brightbill HD, Godowski PJ. Toll genes and responsiveness to bacterial endotoxins [7] (multiple letters) New England Journal of Medicine. 342: 664. PMID 10702066 DOI: 10.1056/NEJM200003023420917  0.8
2000 Brightbill HD, Plevy SE, Modlin RL, Smale ST. A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 164: 1940-51. PMID 10657644 DOI: 10.4049/Jimmunol.164.4.1940  0.8
2000 Gansert JL, Ochoa MT, Krensky AM, Porcelli SA, Modlin RL. Granulysin, a newly described cytolytic protein, may contribute to the tumorolytic effect of nkt cells Blood. 96.  0.8
1999 Naidenko OV, Maher JK, Ernst WA, Sakai T, Modlin RL, Kronenberg M. Binding and antigen presentation of ceramide-containing glycolipids by soluble mouse and human CD1d molecules Journal of Experimental Medicine. 190: 1069-1079. PMID 10523605 DOI: 10.1084/Jem.190.8.1069  0.8
1999 Stenger S, Rosat JP, Bloom BR, Krensky AM, Modlin RL. Granulysin: A lethal weapon of cytolytic T cells Immunology Today. 20: 390-394. PMID 10462738 DOI: 10.1016/S0167-5699(99)01449-8  0.8
1999 Brightbill HD, Libraty DH, Krutzik SR, Yang RB, Belisle JT, Bleharski JR, Maitland M, Norgard MV, Plevy SE, Smale ST, Brennan PJ, Bloom BR, Godowski PJ, Modlin RL. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science (New York, N.Y.). 285: 732-6. PMID 10426995 DOI: 10.1126/Science.285.5428.732  0.8
1999 Modlin RL, Brightbill HD, Godowski PJ. The toll of innate immunity on microbial pathogens. The New England Journal of Medicine. 340: 1834-5. PMID 10362831 DOI: 10.1056/Nejm199906103402312  0.8
1999 Porcelli SA, Modlin RL. The CD1 system: Antigen-presenting molecules for T cell recognition of lipids and glycolipids Annual Review of Immunology. 17: 297-329. PMID 10358761 DOI: 10.1146/Annurev.Immunol.17.1.297  0.8
1999 Stenger S, Modlin RL. T cell mediated immunity to Mycobacterium tuberculosis Current Opinion in Microbiology. 2: 89-93. PMID 10047556 DOI: 10.1016/S1369-5274(99)80015-0  0.8
1999 Sieling PA, Jullien D, Dahlem M, Tedder TF, Rea TH, Modlin RL, Porcelli SA. CD1 expression by dendritic cells in human leprosy lesions: Correlation with effective host immunity Journal of Immunology. 162: 1851-1858. PMID 9973451  0.8
1999 Niazi KR, Chiu MW, Modlin RL. Effects of mutations in the human CD1b antigen-binding groove on functional antigen presentation Journal of Investigative Medicine. 47.  0.8
1998 Mazzaccaro RJ, Stenger S, Rock KL, Porcelli SA, Brenner MB, Modlin RL, Bloom BR. Cytotoxic T lymphocytes in resistance to tuberculosis Advances in Experimental Medicine and Biology. 452: 85-101. PMID 9889963 DOI: 10.1007/978-1-4615-5355-7_11  0.8
1998 Stenger S, Niazi KR, Modlin RL. Down-regulation of CD1 on antigen-presenting cells by infection with Mycobacterium tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 161: 3582-8. PMID 9759880  0.8
1998 Stenger S, Hanson DA, Teitelbaum R, Dewan P, Niazi KR, Froelich CJ, Ganz T, Thoma-Uszynski S, Melián A, Bogdan C, Porcelli SA, Bloom BR, Krensky AM, Modlin RL. An antimicrobial activity of cytolytic T cells mediated by granulysin. Science (New York, N.Y.). 282: 121-5. PMID 9756476 DOI: 10.1126/Science.282.5386.121  0.8
1998 Schlienger K, Uyemura K, Jullien D, Sieling PA, Rea TH, Linsley PS, Modlin RL. B7-1, but not CD28, is crucial for the maintenance of the CD4+ T cell responses in human leprosy. Journal of Immunology (Baltimore, Md. : 1950). 161: 2407-13. PMID 9725237  0.8
1998 Stenger S, Modlin RL. Cytotoxic T cell responses to intracellular pathogens Current Opinion in Immunology. 10: 471-477. PMID 9722925 DOI: 10.1016/S0952-7915(98)80123-4  0.8
1998 Fairhurst RM, Wang CX, Sieling PA, Modlin RL, Braun J. CD1 presents antigens from a gram-negative bacterium, Haemophilus influenzae type b Infection and Immunity. 66: 3523-3526. PMID 9673229 DOI: 10.1128/Iai.66.8.3523-3526.1998  0.8
1998 Fairhurst RM, Wang CX, Sieling PA, Modlin RL, Braun J. CD1-restricted T cells and resistance to polysaccharide-encapsulated bacteria Immunology Today. 19: 257-259. PMID 9639989 DOI: 10.1016/S0167-5699(97)01235-8  0.8
1998 García VE, Jullien D, Song M, Uyemura K, Shuai K, Morita CT, Modlin RL. IL-15 enhances the response of human gamma delta T cells to nonpeptide [correction of nonpetide] microbial antigens. Journal of Immunology (Baltimore, Md. : 1950). 160: 4322-9. PMID 9574535  0.8
1998 Fujieda S, Sieling PA, Modlin RL, Saxon A. CD1-restricted T-cells influence IgG subclass and IgE production Journal of Allergy and Clinical Immunology. 101: 545-551. PMID 9564809 DOI: 10.1016/S0091-6749(98)70362-8  0.8
1998 Jackman RM, Stenger S, Lee A, Moody DB, Rogers RA, Niazi KR, Sugita M, Modlin RL, Peters PJ, Porcelli SA. The tyrosine-containing cytoplasmic tail of CD1b is essential for its efficient presentation of bacterial lipid antigens. Immunity. 8: 341-51. PMID 9529151 DOI: 10.1016/S1074-7613(00)80539-7  0.8
1998 Ernst WA, Maher J, Cho S, Niazi KR, Chatterjee D, Moody DB, Besra GS, Watanabe Y, Jensen PE, Porcelli SA, Kronenberg M, Modlin RL. Molecular interaction of CD1b with lipoglycan antigens. Immunity. 8: 331-40. PMID 9529150 DOI: 10.1016/S1074-7613(00)80538-5  0.8
1998 Morita Y, Yamamura M, Nishida K, Harada S, Okamoto H, Inoue H, Ohmoto Y, Modlin RL, Makino H. Expression of interleukin-12 in synovial tissue from patients with rheumatoid arthritis Arthritis and Rheumatism. 41: 306-314. PMID 9485089 DOI: 10.1002/1529-0131(199802)41:2<306::Aid-Art15>3.0.Co;2-4  0.8
1998 Gong J, Stenger S, Zack JA, Jones BE, Bristol GC, Modlin RL, Morrissey PJ, Barnes PF. Isolation of mycobacterium-reactive CD1-restricted T cells from patients with human immunodeficiency virus infection. The Journal of Clinical Investigation. 101: 383-9. PMID 9435310 DOI: 10.1172/Jci318  0.52
1998 Brightbill HD, Smale ST, Modlin RL. A single control element mediates the activation of the IL-10 promoter: A role for Sp1 in mediating LPS induction of IL-10 gene expression in macrophages Faseb Journal. 12: A1064.  0.8
1998 Sieling PA, Porcelli SA, Spada F, Falcone M, Bloom BR, Diamond B, Modlin RL. CD1c-reactive, Th2 cytokine producing T-cells in human autoimmune disease Faseb Journal. 12.  0.8
1997 Moody DB, Reinhold BB, Guy MR, Beckman EM, Frederique DE, Furlong ST, Ye S, Reinhold VN, Sieling PA, Modlin RL, Besra GS, Porcelli SA. Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells. Science (New York, N.Y.). 278: 283-6. PMID 9323206 DOI: 10.1126/Science.278.5336.283  0.8
1997 Brossay L, Jullien D, Cardell S, Sydora BC, Burdin N, Modlin RL, Kronenberg M. Mouse CD1 Is Mainly Expressed on Hemopoietic-Derived Cells Journal of Immunology. 159: 1216-1224. PMID 9233616  0.8
1997 Stenger S, Mazzaccaro RJ, Uyemura K, Cho S, Barnes PF, Rosat JP, Sette A, Brenner MB, Porcelli SA, Bloom BR, Modlin RL. Differential effects of cytolytic T cell subsets on intracellular infection. Science (New York, N.Y.). 276: 1684-7. PMID 9180075 DOI: 10.1126/Science.276.5319.1684  0.8
1997 Jullien D, Stenger S, Ernst WA, Modlin RL. CD1 presentation of microbial nonpeptide antigens to T cells Journal of Clinical Investigation. 99: 2071-2074. PMID 9151777 DOI: 10.1172/Jci119378  0.8
1997 Castle S, Uyemura K, Wong W, Modlin R, Effros R. Evidence of enhanced type 2 immune response and impaired upregulation of a type 1 response in frail elderly nursing home residents. Mechanisms of Ageing and Development. 94: 7-16. PMID 9147356 DOI: 10.1016/S0047-6374(96)01821-0  0.8
1997 Prigozy TI, Sieling PA, Clemens D, Stewart PL, Behar SM, Porcelli SA, Brenner MB, Modlin RL, Kronenberg M. The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules Immunity. 6: 187-197. PMID 9047240 DOI: 10.1016/S1074-7613(00)80425-2  0.8
1997 Libraty DH, Airan LE, Uyemura K, Jullien D, Spellberg B, Rea TH, Modlin RL. Interferon-gamma differentially regulates interleukin-12 and interleukin-10 production in leprosy. The Journal of Clinical Investigation. 99: 336-41. PMID 9006002 DOI: 10.1172/Jci119162  0.8
1997 Jullien D, Sieling PA, Uyemura K, Mar ND, Rea TH, Modlin RL. IL-15, an immunomodulator of T cell responses in intracellular infection. Journal of Immunology (Baltimore, Md. : 1950). 158: 800-6. PMID 8992997  0.8
1997 Jullien D, Stenger S, Ernst WA, Modlin RL. GD1 presentation of microbial nonpeptide antigens to T cells Journal of Clinical Investigation. 100.  0.8
1996 Ohmen JD, Modlin RL. Evidence for a superantigen in the pathogenesis of tuberculosis Springer Seminars in Immunopathology. 17: 375-384. PMID 8966662 DOI: 10.1007/Bf01795135  0.8
1996 Jullien D, Brossay L, Sieling PA, Modlin RL, Kronenberg M. CD1: Clues on a new antigen-presenting pathway Research in Immunology. 147: 321-328. PMID 8876060 DOI: 10.1016/0923-2494(96)89645-3  0.8
1996 Porcelli SA, Morita CT, Modlin RL. T-cell recognition of non-peptide antigens Current Opinion in Immunology. 8: 510-516. PMID 8794014 DOI: 10.1016/S0952-7915(96)80039-2  0.8
1996 Barnes PF, Modlin RL. Human cellular immune responses to Mycobacterium tuberculosis Current Topics in Microbiology and Immunology. 215: 197-219. PMID 8791715 DOI: 10.1007/978-3-642-80166-2_9  0.8
1996 Gong JH, Zhang M, Modlin RL, Linsley PS, Iyer D, Lin Y, Barnes PF. Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression. Infection and Immunity. 64: 913-8. PMID 8641800 DOI: 10.1128/Iai.64.3.913-918.1996  0.8
1996 Uyemura K, Demer LL, Castle SC, Jullien D, Berliner JA, Gately MK, Warrier RR, Pham N, Fogelman AM, Modlin RL. Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis. The Journal of Clinical Investigation. 97: 2130-8. PMID 8621803 DOI: 10.1172/Jci118650  0.8
1995 Modlin RL, Barnes PF. IL12 and the human immune response to mycohacteria Research in Immunology. 146: 526-531. PMID 8839157 DOI: 10.1016/0923-2494(96)83027-6  0.8
1995 Sieling PA, Sakimura L, Uyemura K, Yamamura M, Oliveros J, Nickoloff BJ, Rea TH, Modlin RL. IL-7 in the cell-mediated immune response to a human pathogen. Journal of Immunology (Baltimore, Md. : 1950). 154: 2775-83. PMID 7876548  0.8
1995 Battistini L, Selmaj K, Kowal C, Ohmen J, Modlin RL, Raine CS, Brosnan CF. Multiple sclerosis: limited diversity of the V delta 2-J delta 3 T-cell receptor in chronic active lesions. Annals of Neurology. 37: 198-203. PMID 7847861 DOI: 10.1002/ana.410370210  0.8
1995 Kim J, Modlin RL, Moy RL, Dubinett SM, McHugh T, Nickoloff BJ, Uyemura K. IL-10 production in cutaneous basal and squamous cell carcinomas. A mechanism for evading the local T cell immune response. Journal of Immunology (Baltimore, Md. : 1950). 155: 2240-7. PMID 7636270  0.8
1995 Modlin RL. Cytokine responses in leprosy lesions Japanese Journal of Leprosy. 64: 85-88. PMID 7592165  0.8
1995 Porcelli SA, Modlin RL. CD1 and the expanding universe of T cell antigens Journal of Immunology. 155: 3709-3710. PMID 7561071  0.8
1995 Modlin RL. T-cell and cytokine patterns in leprosy Japanese Journal of Leprosy. 64: 18-21.  0.8
1994 Modlin RL. Th1-Th2 paradigm: Insights from leprosy Journal of Investigative Dermatology. 102: 828-832. PMID 8006444 DOI: 10.1111/1523-1747.Ep12381958  0.8
1994 Zhang M, Gong J, Iyer DV, Jones BE, Modlin RL, Barnes PF. T cell cytokine responses in persons with tuberculosis and human immunodeficiency virus infection. The Journal of Clinical Investigation. 94: 2435-42. PMID 7989601 DOI: 10.1172/Jci117611  0.8
1994 Sieling PA, Modlin RL. Regulation of cytokine patterns in leprosy Annals of the New York Academy of Sciences. 730: 42-52. PMID 7915896 DOI: 10.1111/J.1749-6632.1994.Tb44238.X  0.8
1994 Ohmen JD, Barnes PF, Grimm CL, Bloom BR, Modlin RL. Evidence for a superantigen in human tuberculosis Immunity. 1: 35-43. PMID 7889397 DOI: 10.1016/1074-7613(94)90007-8  0.8
1994 Ohmen JD, Moy RL, Zovich D, Lieberman A, Wyzykowski RJ, Sullivan L, Modlin RL, Uyemura K. Selective accumulation of T cells according to T-cell receptor V beta gene usage in skin cancer. The Journal of Investigative Dermatology. 103: 751-7. PMID 7798611 DOI: 10.1111/1523-1747.Ep12412288  0.8
1994 Sieling PA, Modlin RL. Cytokine patterns at the site of mycobacterial infection Immunobiology. 191: 378-387. PMID 7713551 DOI: 10.1016/S0171-2985(11)80443-2  0.8
1993 Sieling PA, Abrams JS, Yamamura M, Salgame P, Bloom BR, Rea TH, Modlin RL. Immunosuppressive Roles for IL-10 and IL-4 in Human Infection: In Vitro Modulation of T cell Responses in Leprosy Journal of Immunology. 150: 5501-5510. PMID 8515073  0.8
1993 Pirmez C, Yamamura M, Uyemura K, Paes-Oliveira M, Conceição-Silva F, Modlin RL. Cytokine patterns in the pathogenesis of human leishmaniasis. The Journal of Clinical Investigation. 91: 1390-5. PMID 8473490 DOI: 10.1172/Jci116341  0.8
1993 Yamamura M, Modlin RL, Ohmen JD, Moy RL. Local expression of antiinflammatory cytokines in cancer Journal of Clinical Investigation. 91: 1005-1010. PMID 8450029 DOI: 10.1172/Jci116256  0.8
1993 Cáceres-Dittmar G, Tapia FJ, Sánchez MA, Yamamura M, Uyemura K, Modlin RL, Bloom BR, Convit J. Determination of the cytokine profile in American cutaneous leishmaniasis using the polymerase chain reaction. Clinical and Experimental Immunology. 91: 500-5. PMID 8443970 DOI: 10.1111/j.1365-2249.1993.tb05931.x  0.8
1993 Wang XH, Ohmen JD, Uyemura K, Rea TH, Kronenberg M, Modlin RL. Selection of T lymphocytes bearing limited T-cell receptor beta chains in the response to a human pathogen. Proceedings of the National Academy of Sciences of the United States of America. 90: 188-92. PMID 8419921 DOI: 10.1073/Pnas.90.1.188  0.8
1993 Barnes PF, Abrams JS, Lu S, Sieling PA, Rea TH, Modlin RL. Patterns of cytokine production by mycobacterium-reactive human T-cell clones Infection and Immunity. 61: 197-203. PMID 8418042 DOI: 10.1128/Iai.61.1.197-203.1993  0.8
1993 Barnes PF, Lu S, Abrams JS, Wang E, Yamamura M, Modlin RL. Cytokine production at the site of disease in human tuberculosis Infection and Immunity. 61: 3482-3489. PMID 8335379 DOI: 10.1128/Iai.61.8.3482-3489.1993  0.8
1993 Wang X, Golkar L, Uyemura K, Ohmen JD, Villahermosa LG, Fajardo TT, Cellona RV, Walsh GP, Modlin RL. T cells bearing V beta 6 T cell receptors in the cell-mediated immune response to Mycobacterium leprae. Journal of Immunology (Baltimore, Md. : 1950). 151: 7105-16. PMID 8258714  0.8
1993 Modlin RL, Bloom BR. Immune regulation: Learning from leprosy Hospital Practice. 28: 71-74+77. PMID 8227249 DOI: 10.1080/21548331.1993.11442874  0.8
1993 Modlin RL, Nutman TB. Type 2 cytokines and negative immune regulation in human infections Current Opinion in Immunology. 5: 511-517. PMID 8216926 DOI: 10.1016/0952-7915(93)90031-M  0.8
1993 Uyemura K, Pirmez C, Sieling PA, Kiene K, Paes-Oliveira M, Modlin RL. CD4+ type 1 and CD8+ type 2 T cell subsets in human leishmaniasis have distinct T cell receptor repertoires. Journal of Immunology (Baltimore, Md. : 1950). 151: 7095-104. PMID 7903101  0.8
1993 Uyemura K, Yamamura M, Fivenson DF, Modlin RL, Nickoloff BJ. The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response. The Journal of Investigative Dermatology. 101: 701-5. PMID 7693825 DOI: 10.1111/1523-1747.Ep12371679  0.8
1992 Barnes PF, Chatterjee D, Brennan PJ, Rea TH, Modlin RL. Tumor necrosis factor production in patients with leprosy Infection and Immunity. 60: 1441-1446. PMID 1548069 DOI: 10.1128/Iai.60.4.1441-1446.1992  0.8
1992 Barnes PF, Grisso CL, Abrams JS, Band H, Rea TH, Modlin RL. γδ T Lymphocytes in Human Tuberculosis Journal of Infectious Diseases. 165: 506-512. PMID 1538155 DOI: 10.1093/infdis/165.3.506  0.8
1992 Bloom BR, Modlin RL, Salgame P. Stigma variations: Observations on suppressor T cells and leprosy Annual Review of Immunology. 10: 453-488. PMID 1534241 DOI: 10.1146/Annurev.Iy.10.040192.002321  0.8
1992 Modlin RL, Lewis J, Uyemura K, Tigelaar RE. T lymphocytes bearing gamma-delta antigen receptors in skin. Chemical Immunology. 53: 61-74. PMID 1534236 DOI: 10.1159/000319103  0.8
1992 Uyemura K, Klotz J, Pirmez C, Ohmen J, Wang XH, Ho C, Hoffman WL, Modlin RL. Microanatomic clonality of gamma delta T cells in human leishmaniasis lesions. Journal of Immunology (Baltimore, Md. : 1950). 148: 1205-11. PMID 1531352  0.8
1992 Yamamura M, Wang XH, Ohmen JD, Uyemura K, Rea TH, Bloom BR, Modlin RL. Cytokine patterns of immunologically mediated tissue damage. Journal of Immunology (Baltimore, Md. : 1950). 149: 1470-5. PMID 1500726  0.8
1992 Uyemura K, Ho CT, Ohmen JD, Rea TH, Modlin RL. Selective expansion of V delta 1 + T cells from leprosy skin lesions. The Journal of Investigative Dermatology. 99: 848-52. PMID 1469299 DOI: 10.1111/1523-1747.Ep12614809  0.8
1992 Sieling PA, Modlin RL. T cell and cytokine patterns in leprosy skin lesions Springer Seminars in Immunopathology. 13: 413-426. PMID 1411906 DOI: 10.1007/Bf00200538  0.8
1992 Salgame P, Yamamura M, Bloom BR, Modlin RL. Evidence for functional subsets of CD4+ and CD8+ T cells in human disease: Lymphokine patterns in leprosy Chemical Immunology. 54: 44-59. PMID 1358110  0.8
1992 Uyemura K, Ohmen JD, Grisso CL, Sieling PA, Wyzykowski R, Reisinger DM, Rea TH, Modlin RL. Limited T-cell receptor beta-chain diversity of a T-helper cell type 1-like response to Mycobacterium leprae. Infection and Immunity. 60: 4542-8. PMID 1328060 DOI: 10.1128/Iai.60.11.4542-4548.1992  0.8
1991 Rea TH, Modlin RL. Immunopathology of leprosy skin lesions Seminars in Dermatology. 10: 188-193. PMID 1931567  0.8
1991 Yamamura M, Uyemura K, Deans RJ, Weinberg K, Rea TH, Bloom BR, Modlin RL. Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science (New York, N.Y.). 254: 277-9. PMID 1925582 DOI: 10.1126/Science.1925582  0.8
1991 Pope RM, Landay A, Modlin RL, Lessard J, Koch AE. γ δ T cell receptor positive T cells in the inflammatory joint: Lack of association with response to soluble antigens Cellular Immunology. 137: 127-138. PMID 1909213 DOI: 10.1016/0008-8749(91)90063-H  0.8
1991 Born WK, Harshan K, Modlin RL, O'Brien RL. The role of gamma delta T lymphocytes in infection. Current Opinion in Immunology. 3: 455-9. PMID 1836730 DOI: 10.1016/0952-7915(91)90002-I  0.8
1991 Uyemura K, Band H, Ohmen J, Brenner MB, Rea TH, Modlin RL. Gamma delta T cells in leprosy lesions. Current Topics in Microbiology and Immunology. 173: 203-7. PMID 1833144  0.8
1991 Sullivan L, Sano S, Pirmez C, Salgame P, Mueller C, Hofman F, Uyemura K, Rea TH, Bloom BR, Modlin RL. Expression of adhesion molecules in leprosy lesions. Infection and Immunity. 59: 4154-60. PMID 1718871 DOI: 10.1128/Iai.59.11.4154-4160.1991  0.8
1991 Born WK, O'Brien RL, Modlin RL. Antigen specificity of gamma delta T lymphocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2699-705. PMID 1717333  0.8
1991 Grau GE, Modlin RL. Immune mechanisms in bacterial and parasitic diseases: protective immunity versus pathology Current Opinion in Immunology. 3: 480-485. PMID 1684508 DOI: 10.1016/0952-7915(91)90007-N  0.8
1991 Salgame P, Abrams JS, Clayberger C, Goldstein H, Convit J, Modlin RL, Bloom BR. Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones Science. 254: 279-282. PMID 1681588 DOI: 10.1126/Science.1681588  0.8
1991 Panchamoorthy G, McLean J, Modlin RL, Morita CT, Ishikawa S, Brenner MB, Band H. A predominance of the T cell receptor Vγ2/Vδ2 subset in human mycobacteria-responsive T cells suggests germline gene encoded recognition Journal of Immunology. 147: 3360-3369. PMID 1658147  0.8
1991 Ohmen JD, Barnes PF, Uyemura K, Lu SZ, Grisso CL, Modlin RL. The T cell receptors of human gamma delta T cells reactive to Mycobacterium tuberculosis are encoded by specific V genes but diverse V-J junctions. Journal of Immunology (Baltimore, Md. : 1950). 147: 3353-9. PMID 1658146  0.8
1991 Uyemura K, Deans RJ, Band H, Ohmen J, Panchamoorthy G, Morita CT, Rea TH, Modlin RL. Evidence for clonal selection of gamma/delta T cells in response to a human pathogen. The Journal of Experimental Medicine. 174: 683-92. PMID 1651977 DOI: 10.1084/Jem.174.3.683  0.8
1991 Uyemura K, Ohmen J, Brenner MB, Rea TH, Modlin RL. γδ T Cells in Leprosy Lesions Current Topics in Microbiology and Immunology. 173: 203-207. DOI: 10.1007/978-3-642-76492-9_28  0.36
1990 Mehra V, Modlin RL. T-lymphocytes in leprosy lesions Current Topics in Microbiology and Immunology. 155: 97-109. PMID 2137768  0.8
1990 Barnes PF, Fong SJ, Brennan PJ, Twomey PE, Mazumder A, Modlin RL. Local production of tumor necrosis factor and IFN-γ in tuberculous pleuritis Journal of Immunology. 145: 149-154. PMID 2113553  0.8
1990 Pirmez C, Cooper C, Paes-Oliveira M, Schubach A, Torigian VK, Modlin RL. Immunologic responsiveness in American cutaneous leishmaniasis lesions Journal of Immunology. 145: 3100-3104. PMID 1976709  0.8
1989 Hunter SW, McNeil M, Modlin RL, Mehra V, Bloom BR, Brennan PJ. Isolation and characterization of the highly immunogenic cell wall-associated protein of Mycobacterium leprae Journal of Immunology. 142: 2864-2872. PMID 2649561  0.8
1989 Barnes PF, Modlin RL, Bikle DD, Adams JS. Transpleural gradient of 1,25-dihydroxyvitamin D in tuberculous pleuritis Journal of Clinical Investigation. 83: 1527-1532. PMID 2540219 DOI: 10.1172/Jci114048  0.8
1989 Salgame P, Modlin R, Bloom BR. On the mechanism of human T cell suppression International Immunology. 1: 121-129. PMID 2535060 DOI: 10.1093/Intimm/1.2.121  0.8
1989 Cooper CL, Mueller C, Sinchaisri TA, Pirmez C, Chan J, Kaplan G, Young SM, Weissman IL, Bloom BR, Rea TH, Modlin RL. Analysis of naturally occurring delayed-type hypersensitivity reactions in leprosy by in situ hybridization. The Journal of Experimental Medicine. 169: 1565-81. PMID 2523952 DOI: 10.1084/Jem.169.5.1565  0.8
1989 Adams JS, Modlin RL, Diz MM, Barnes PF. Potentiation of the macrophage 25-hydroxyvitamin D-1-hydroxylation reaction by human tuberculous pleural effusion fluid Journal of Clinical Endocrinology and Metabolism. 69: 457-460. PMID 2502557 DOI: 10.1210/Jcem-69-2-457  0.8
1989 Wong L, Salgame P, Torigian VK, Fu TH, Rea TH, Modlin RL. CD2 expression and function in lepromatous leprosy Infection and Immunity. 57: 2815-2819. PMID 2474503 DOI: 10.1128/Iai.57.9.2815-2819.1989  0.8
1989 Modlin RL, Pirmez C, Hofman FM, Torigian V, Uyemura K, Rea TH, Bloom BR, Brenner MB. Lymphocytes bearing antigen-specific gamma delta T-cell receptors accumulate in human infectious disease lesions. Nature. 339: 544-8. PMID 2471938 DOI: 10.1038/339544A0  0.8
1989 Barnes PF, Mistry SD, Cooper CL, Pirmez C, Rea TH, Modlin RL. Compartmentalization of a CD4+ T lymphocyte subpopulation in tuberculous pleuritis. Journal of Immunology (Baltimore, Md. : 1950). 142: 1114-9. PMID 2464638  0.8
1988 Barnes PF, Leedom JM, Chan LS, Wong SF, Shah J, Vachon LA, Overturf GD, Modlin RL. Predictors of short-term prognosis in patients with pulmonary tuberculosis Journal of Infectious Diseases. 158: 366-371. PMID 3403993 DOI: 10.1093/Infdis/158.2.366  0.8
1988 Melancon-Kaplan J, Hunter SW, McNeil M, Stewart C, Modlin RL, Rea TH, Convit J, Salgame P, Mehra V, Bloom BR, Brennan PJ. Immunological significance of Mycobacterium leprae cell walls Proceedings of the National Academy of Sciences of the United States of America. 85: 1917-1921. PMID 3279420 DOI: 10.1073/Pnas.85.6.1917  0.8
1988 Modlin RL, Rea TH. Immunopathology of leprosy granulomas Springer Seminars in Immunopathology. 10: 359-374. PMID 3065952 DOI: 10.1007/Bf02053846  0.8
1988 Ellner JJ, Barnes PF, Wallis RS, Modlin RL. The immunology of tuberculous pleurisy Seminars in Respiratory Infections. 3: 335-342. PMID 2463656  0.8
1987 Fullmer MA, Shen JY, Modlin RL, Rea TH. Immunohistological evidence of lymphokine production and lymphocyte activation antigens in tuberculin reactions Clinical and Experimental Immunology. 67: 383-390. PMID 3038437  0.8
1987 Modlin RL, Brenner MB, Krangel MS, Duby AD, Bloom BR. T-cell receptors of human suppressor cells Nature. 329: 541-545. PMID 2958712 DOI: 10.1038/329541A0  0.8
1987 Modlin RL, Rea TH. Leprosy: New insight into an ancient disease Journal of the American Academy of Dermatology. 17: 1-13. PMID 2956292 DOI: 10.1016/S0190-9622(87)70164-9  0.8
1987 Nelson EE, Wong L, Uyemura K, Rea TH, Modlin RL. Lepromin-induced suppressor cells in lepromatous leprosy. Cellular Immunology. 104: 99-104. PMID 2948676 DOI: 10.1016/0008-8749(87)90010-4  0.8
1987 Shen JY, Hofman FM, Gunter JR, Modlin RL, Rea TH. In situ identification of activated Ta1+ T lymphocytes in human leprosy skin lesions International Journal of Leprosy. 55: 494-498. PMID 2443587  0.8
1987 Rea TH, Modlin RL. Characterization of CD4-positive T-lymphocyte subsets in leprosy granulomas International Journal of Leprosy. 55: 786-786.  0.8
1986 Lynch NR, Malavé C, Ifante RB, Modlin RL, Convit J. In situ detection of amastigotes in American cutaneous leishmaniasis, using monoclonal antibodies Transactions of the Royal Society of Tropical Medicine and Hygiene. 80: 6-9. PMID 3523865 DOI: 10.1016/0035-9203(86)90183-5  0.8
1986 Modlin RL, Ormerod LD, Walsh GP, Rea TH, Meyers WM, Binford CH, Martin LN, Wolf RH, Gormus BJ. In situ characterization of T lymphocyte subpopulations in leprosy in the mangabey monkey Clinical and Experimental Immunology. 65: 260-264. PMID 3491704  0.8
1986 Modlin RL, Gersuk GM, Nelson EE, Pattengale PK, Gunter JR, Chen L, Cooper CL, Bloom BR, Rea TH. T-lymphocyte clones from leprosy skin lesions. Leprosy Review. 57: 143-7. PMID 2952855 DOI: 10.5935/0305-7518.19860065  0.8
1986 Uyemura K, Dixon JF, Wong L, Rea TH, Modlin RL. Effect of cyclosporine A in erythema nodosum leprosum. Journal of Immunology (Baltimore, Md. : 1950). 137: 3620-3. PMID 2946765  0.8
1986 Modlin RL, Mehra V, Wong L, Fujimiya Y, Chang WC, Horwitz DA, Bloom BR, Rea TH, Pattengale PK. Suppressor T lymphocytes from lepromatous leprosy skin lesions Journal of Immunology. 137: 2831-2834. PMID 2944966  0.8
1986 Modlin RL, Kato H, Mehra V, Nelson EE, Fan XD, Rea TH, Pattengale PK, Bloom BR. Genetically restricted suppressor T-cell clones derived from lepromatous leprosy lesions. Nature. 322: 459-61. PMID 2942780 DOI: 10.1038/322459A0  0.36
1986 Rea TH, Shen JY, Modlin RL. Epidermal keratinocyte Ia expression, Langerhans cell hyperplasia and lymphyocytic infiltration in skin lesions of leprosy Clinical and Experimental Immunology. 65: 253-259. PMID 2431817  0.8
1986 Modlin RL, Mehra V, Jordan R, Bloom BR, Rea TH. In situ and in vitro characterization of the cellular immune response in erythema nodosum leprosum Journal of Immunology. 136: 883-886. PMID 2416837  0.8
1985 Meyer PR, Ormerod LD, Osborn KG, Lowenstine LJ, Hendrickson RV, Modlin RL, Smith RE, Gardner MB, Taylor CR. An immunopathologic evaluation of lymph nodes from monkey and man with acquired immune deficiency syndrome and related conditions Hematological Oncology. 3: 199-210. PMID 4043931 DOI: 10.1002/Hon.2900030308  0.8
1985 Dugan E, Modlin RL, Rea TH. An in situ immunohistological study of Mitsuda reactions. International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association. 53: 404-9. PMID 3900247  0.8
1985 Modlin RL, Segal GP, Hofman FM, Walley MS, Johnson RH, Taylor CR, Rea TH. In situ localization of T lymphocytes in disseminated coccidioidomycosis Journal of Infectious Diseases. 151: 314-319. PMID 3155781 DOI: 10.1093/Infdis/151.2.314  0.8
1985 Hofman FM, Modlin RL, Bhoopat L, Taylor CR. Distribution of cells bearing the TAC antigen during ontogeny of human lymphoid tissue Journal of Immunology. 134: 3751-3755. PMID 2985695  0.8
1985 Modlin RL, Bakke AC, Vaccaro SA, Horwitz DA, Taylor CR, Rea TH. Tissue and Blood T-Lymphocyte Subpopulations in Erythema Nodosum Leprosum Archives of Dermatology. 121: 216-219. DOI: 10.1001/Archderm.1985.01660020074021  0.8
1985 Imam A, Mitchell MS, Modlin RL. Human monoclonal antibodies that distinguish cutaneous malignant melanomas from benign nevi in fixed tissue sections Proceedings of the American Association For Cancer Research 0.8
1984 Modlin RL, Horwitz DA, Jordan RR, Gebhard JF, Taylor CR, Rea TH. Immunopathologic demonstration of T lymphocyte subpopulations and interleukin 2 in granuloma annulare Pediatric Dermatology. 2: 26-32. PMID 6438616  0.8
1984 Modlin RL, Kempf RA, Mitchell MS, Taylor CR, Davis CR, Rea TH. Kaposi's sarcoma and autoimmune thrombocytopenia Cancer Investigation. 2: 97-101. PMID 6428708 DOI: 10.3109/07357908409020292  0.8
1984 Modlin RL, Rowden G, Taylor CR, Rea TH. Comparison of S-100 and OKT6 antisera in human skin Journal of Investigative Dermatology. 83: 206-209. PMID 6381607 DOI: 10.1111/1523-1747.Ep12263574  0.8
1984 Modlin RL, Vaccaro SA, Gottlieb B, Gebhard JF, Linden CE, Forni M, Meyer PR, Taylor CR, Rea TH. Granuloma annulare. Identification of cells in the cutaneous infiltrate by immunoperoxidase techniques Archives of Pathology and Laboratory Medicine. 108: 379-382. PMID 6370193  0.8
1984 Rea TH, Bakke AC, Parker JW, Modlin RL, Horwitz DA. Peripheral blood T lymphocyte subsets in leprosy International Journal of Leprosy. 52: 311-317. PMID 6332790  0.8
1984 Modlin RL, Hofman FM, Horwitz DA, Husmann LA, Gillis S, Taylor CR, Rea TH. In situ identification of cells in human leprosy granulomas with monoclonal antibodies to interleukin 2 and its receptor Journal of Immunology. 132: 3085-3090. PMID 6327818  0.8
1984 Modlin RL, Hofman FM, Sharma OP, Gottlieb B, Taylor CR, Rea TH. Demonstration in situ of subsets of T-lymphocytes in sarcoidosis American Journal of Dermatopathology. 6: 423-426. PMID 6239559 DOI: 10.1097/00000372-198410000-00002  0.8
1984 Modlin RL, Gottlieb B, Taylor C, Rea TH. Identification of cells lining pseudovascular spaces of benign pigmented nevi American Journal of Dermatopathology. 6: 25-29. PMID 6084957  0.8
1983 Meyer PR, Modlin RL, Powars D, Ewing N, Parker JW, Taylor CR. Altered distribution of T-lymphocyte subpopulations in lymph nodes from patients with acquired immunodeficiency-like syndrome and hemphilia The Journal of Pediatrics. 103: 407-410. PMID 6411884 DOI: 10.1016/S0022-3476(83)80414-4  0.8
1983 Modlin RL, Hofman FM, Kempf RA, Taylor CR, Conant MA, Rea TH. Kaposi's sarcoma in homosexual men: An immunohistochemical study Journal of the American Academy of Dermatology. 8: 620-627. PMID 6408146 DOI: 10.1016/S0190-9622(83)70067-8  0.8
1983 Taylor CR, Hofman FM, Modlin RL, Rea TH. Immunoperoxidase techniques applied to dermatopathology Journal of Cutaneous Pathology. 10: 145-163. PMID 6345613 DOI: 10.1111/J.1600-0560.1983.Tb00321.X  0.8
1983 Hofman FM, Meyer PR, Yanagihara E, Modlin RL, Rea TH, Parker JW, Lukes RJ, Taylor CR. Demonstration of a subpopulation of Ia+ T-helper cells in mycosis fungoides and the Sézary syndrome. The American Journal of Dermatopathology. 5: 135-43. PMID 6224436 DOI: 10.1097/00000372-198304000-00011  0.8
1983 Modlin RL, Gebhard JF, Taylor CR, Rea TH. In situ characterization of T lymphocyte subsets in the reactional states of leprosy Clinical and Experimental Immunology. 53: 17-24. PMID 6223731  0.8
1983 Modlin RL, Hofman FM, Meyer PR, Sharma OP, Taylor CR, Rea TH. In situ demonstration of T lymphocyte subsets in granulomatous inflammation: Leprosy, rhinoscleroma and sarcoidosis Clinical and Experimental Immunology. 51: 430-438. PMID 6221839  0.8
1983 Modlin RL, Hofman FM, Taylor CR, Rea TH. T lymphocyte subsets in the skin lesions of patients with leprosy Journal of the American Academy of Dermatology. 8: 182-189. PMID 6219136 DOI: 10.1016/S0190-9622(83)70021-6  0.8
1983 Modlin RL. Kaposi's sarcoma: Current trends Western Journal of Medicine. 138: 862-863.  0.8
1982 Modlin RL, Hofman FM, Taylor CR, Rea TH. In situ characterization of T lymphocyte subsets in leprosy granulomas International Journal of Leprosy. 50: 361-362. PMID 6982876  0.8
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