Debra A. Kendall - Publications

University of Connecticut, Storrs, CT, United States 
Molecular Biology, Cell Biology, Microbiology Biology

101 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tahtouh T, Durieu E, Villiers B, Bruyère C, Nguyen TL, Fant X, Ahn KH, Khurana L, Deau E, Lindberg MF, Sévère E, Miege F, Roche D, Limanton E, L'Helgoual'ch JM, ... ... Kendall DA, et al. Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors. Journal of Medicinal Chemistry. PMID 34928152 DOI: 10.1021/acs.jmedchem.1c01141  0.433
2020 Schurman LD, Lu D, Kendall DA, Howlett AC, Lichtman AH. Molecular Mechanism and Cannabinoid Pharmacology. Handbook of Experimental Pharmacology. PMID 32236882 DOI: 10.1007/164_2019_298  0.386
2020 Dopart R, Immadi SS, Lu D, Kendall DA. Structural Optimization of the Diarylurea PSNCBAM-1, an Allosteric Modulator of Cannabinoid Receptor 1. Current Therapeutic Research, Clinical and Experimental. 92: 100574. PMID 32021660 DOI: 10.1016/J.Curtheres.2019.100574  0.368
2019 Mustafa M, Donvito G, Moncayo L, Swafford A, Poklis J, Grauer R, Olszewska T, Kendall DA, Lu D, Lichtman AH. In vivo evaluation of the CB allosteric modulator LDK1258 reveals CB-receptor independent behavioral effects. Pharmacology, Biochemistry, and Behavior. 172840. PMID 31899221 DOI: 10.1016/J.Pbb.2019.172840  0.359
2019 Dopart R, Kendall DA. Allosteric modulators restore orthosteric agonist binding to mutated CB receptors. The Journal of Pharmacy and Pharmacology. PMID 31722122 DOI: 10.1111/Jphp.13193  0.451
2019 Scott CE, Tang Y, Alt A, Burford NT, Gerritz SW, Ogawa LM, Zhang L, Kendall DA. Identification and biochemical analyses of selective CB agonists. European Journal of Pharmacology. PMID 30951717 DOI: 10.1016/J.Ejphar.2019.03.054  0.438
2018 Immadi SS, Dopart R, Wu Z, Fu B, Kendall DA, Lu D. Exploring 6-Azaindole and 7-Azaindole Rings for Developing Cannabinoid Receptor 1 Allosteric Modulators. Cannabis and Cannabinoid Research. 3: 252-258. PMID 30547095 DOI: 10.1089/can.2018.0046  0.338
2018 Lu D, Immadi SS, Wu Z, Kendall DA. Translational potential of allosteric modulators targeting the cannabinoid CB receptor. Acta Pharmacologica Sinica. PMID 30333554 DOI: 10.1038/S41401-018-0164-X  0.411
2018 Jagla CAD, Scott CE, Tang Y, Qiao C, Mateo-Semidey GE, Yudowski GA, Lu D, Kendall DA. Pyrimidinyl Biphenylureas Act as Allosteric Modulators to activate Cannabinoid Receptor 1 and initiate β-Arrestin-dependent Responses. Molecular Pharmacology. PMID 30322873 DOI: 10.1124/Mol.118.112854  0.362
2018 Dopart R, Lu D, Lichtman AH, Kendall DA. Allosteric modulators of cannabinoid receptor 1: developing compounds for improved specificity. Drug Metabolism Reviews. 1-11. PMID 29355030 DOI: 10.1080/03602532.2018.1428342  0.422
2017 Nogueras-Ortiz C, Roman-Vendrell C, Mateo-Semidey GE, Liao YH, Kendall DA, Yudowski GA. Retromer stops beta-arrestin 1 mediated signaling from internalized cannabinoid 2 receptors. Molecular Biology of the Cell. PMID 28954865 DOI: 10.1091/Mbc.E17-03-0198  0.425
2017 Scott CE, Kendall DA. Assessing Allosteric Modulation of CB1 at the Receptor and Cellular Levels. Methods in Enzymology. 593: 317-342. PMID 28750809 DOI: 10.1016/Bs.Mie.2017.05.002  0.453
2017 Khurana L, Mackie K, Piomelli D, Kendall DA. Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology. PMID 28527758 DOI: 10.1016/J.Neuropharm.2017.05.018  0.416
2017 Khurana L, Fu B, Duddupudi AL, Liao YH, Immadi SS, Kendall DA, Lu D. Pyrimidinyl Biphenylureas: Identification of New Lead Compounds as Allosteric Modulators of the Cannabinoid Receptor CB1. Journal of Medicinal Chemistry. PMID 28059509 DOI: 10.1021/Acs.Jmedchem.6B01448  0.372
2016 Kendall DA, Yudowski GA. Cannabinoid Receptors in the Central Nervous System: Their Signaling and Roles in Disease. Frontiers in Cellular Neuroscience. 10: 294. PMID 28101004 DOI: 10.3389/Fncel.2016.00294  0.41
2016 Qiao CJ, Ali HI, Ahn KH, Kolluru S, Kendall DA, Lu D. Synthesis and biological evaluation of indole-2-carboxamides bearing photoactivatable functionalities as novel allosteric modulators for the cannabinoid CB1 receptor. European Journal of Medicinal Chemistry. 121: 517-529. PMID 27318976 DOI: 10.1016/J.Ejmech.2016.05.044  0.564
2016 Delgado-Peraza F, Ahn K, Nogueras-Ortiz C, Mungrue I, Mackie KP, Kendall DA, Yudowski G. Mechanisms of biased beta-arrestin mediated signaling downstream from the cannabinoid 1 receptor. Molecular Pharmacology. PMID 27009233 DOI: 10.1124/Mol.115.103176  0.547
2016 Shim JY, Khurana L, Kendall DA. Computational analysis of the CB1 carboxyl-terminus in the receptor-G protein complex. Proteins. 84: 532-43. PMID 26994549 DOI: 10.1002/Prot.24999  0.331
2015 Scott C, Ahn KH, Graf ST, Goddard Iii WA, Kendall DA, Abrol R. Computational Prediction and Biochemical Analyses of New Inverse Agonists for the CB1 Receptor. Journal of Chemical Information and Modeling. PMID 26633590 DOI: 10.1021/Acs.Jcim.5B00581  0.612
2015 Picone RP, Kendall DA. Minireview: from the bench, toward the clinic: therapeutic opportunities for cannabinoid receptor modulation. Molecular Endocrinology (Baltimore, Md.). 29: 801-13. PMID 25866875 DOI: 10.1210/Me.2015-1062  0.389
2015 Mahmoud MM, Olszewska T, Liu H, Shore DM, Hurst DP, Reggio PH, Lu D, Kendall DA. (4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)(cyclohexyl)methanone hydrochloride (LDK1229): a new cannabinoid CB1 receptor inverse agonist from the class of benzhydryl piperazine analogs. Molecular Pharmacology. 87: 197-206. PMID 25411367 DOI: 10.1124/Mol.114.095471  0.429
2014 Flores-Otero J, Ahn KH, Delgado-Peraza F, Mackie K, Kendall DA, Yudowski GA. Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1. Nature Communications. 5: 4589. PMID 25081814 DOI: 10.1038/Ncomms5589  0.599
2014 Wowor AJ, Yan Y, Auclair SM, Yu D, Zhang J, May ER, Gross ML, Kendall DA, Cole JL. Analysis of SecA dimerization in solution. Biochemistry. 53: 3248-60. PMID 24786965 DOI: 10.1021/Bi500348P  0.779
2014 Khurana L, Ali HI, Olszewska T, Ahn KH, Damaraju A, Kendall DA, Lu D. Optimization of chemical functionalities of indole-2-carboxamides to improve allosteric parameters for the cannabinoid receptor 1 (CB1). Journal of Medicinal Chemistry. 57: 3040-52. PMID 24635495 DOI: 10.1021/Jm5000112  0.614
2014 Bhanu MK, Kendall DA. Fluorescence spectroscopy of soluble E. coli SPase I Δ2-75 reveals conformational changes in response to ligand binding. Proteins. 82: 596-606. PMID 24115229 DOI: 10.1002/Prot.24429  0.489
2014 Wowor AJ, Yan Y, Auclair SM, Yu D, Gross ML, Kendall DA, Cole JL. The Seca Dimer Interface Biophysical Journal. 106: 476a. DOI: 10.1016/J.Bpj.2013.11.2691  0.784
2013 Shim JY, Ahn KH, Kendall DA. Molecular basis of cannabinoid CB1 receptor coupling to the G protein heterotrimer Gαiβγ: identification of key CB1 contacts with the C-terminal helix α5 of Gαi. The Journal of Biological Chemistry. 288: 32449-65. PMID 24092756 DOI: 10.1074/Jbc.M113.489153  0.621
2013 Mahmoud MM, Ali HI, Ahn KH, Damaraju A, Samala S, Pulipati VK, Kolluru S, Kendall DA, Lu D. Structure-activity relationship study of indole-2-carboxamides identifies a potent allosteric modulator for the cannabinoid receptor 1 (CB1). Journal of Medicinal Chemistry. 56: 7965-75. PMID 24053617 DOI: 10.1021/Jm4009828  0.621
2013 Bhanu MK, Zhao P, Kendall DA. Mapping of the SecA signal peptide binding site and dimeric interface by using the substituted cysteine accessibility method. Journal of Bacteriology. 195: 4709-15. PMID 23935053 DOI: 10.1128/Jb.00661-13  0.542
2013 Yu D, Wowor AJ, Cole JL, Kendall DA. Defining the Escherichia coli SecA dimer interface residues through in vivo site-specific photo-cross-linking. Journal of Bacteriology. 195: 2817-25. PMID 23585536 DOI: 10.1128/Jb.02269-12  0.441
2013 Ahn KH, Mahmoud MM, Shim JY, Kendall DA. Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1). The Journal of Biological Chemistry. 288: 9790-800. PMID 23449980 DOI: 10.1074/Jbc.M112.438804  0.644
2013 Ahn KH, Scott CE, Abrol R, Goddard WA, Kendall DA. Computationally-predicted CB1 cannabinoid receptor mutants show distinct patterns of salt-bridges that correlate with their level of constitutive activity reflected in G protein coupling levels, thermal stability, and ligand binding. Proteins. 81: 1304-17. PMID 23408552 DOI: 10.1002/Prot.24264  0.613
2013 Ahn KH, Mahmoud MM, Samala S, Lu D, Kendall DA. Profiling two indole-2-carboxamides for allosteric modulation of the CB1 receptor. Journal of Neurochemistry. 124: 584-9. PMID 23205875 DOI: 10.1111/Jnc.12115  0.624
2013 Scott CE, Abrol R, Ahn KH, Kendall DA, Goddard WA. Molecular basis for dramatic changes in cannabinoid CB1 G protein-coupled receptor activation upon single and double point mutations. Protein Science : a Publication of the Protein Society. 22: 101-13. PMID 23184890 DOI: 10.1002/Pro.2192  0.583
2013 Wowor AJ, Auclair SM, Yu D, Kendall DA, Cole JL. Elucidating the Dimer Interface of Seca Biophysical Journal. 104: 553a. DOI: 10.1016/J.Bpj.2012.11.3066  0.767
2012 Shim JY, Bertalovitz AC, Kendall DA. Probing the interaction of SR141716A with the CB1 receptor. The Journal of Biological Chemistry. 287: 38741-54. PMID 22995906 DOI: 10.1074/Jbc.M112.390955  0.795
2012 Ahn KH, Mahmoud MM, Kendall DA. Allosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activation. The Journal of Biological Chemistry. 287: 12070-82. PMID 22343625 DOI: 10.1074/Jbc.M111.316463  0.653
2012 De Bona P, Deshmukh L, Gorbatyuk V, Vinogradova O, Kendall DA. Structural studies of a signal peptide in complex with signal peptidase I cytoplasmic domain: the stabilizing effect of membrane-mimetics on the acquired fold. Proteins. 80: 807-17. PMID 22113858 DOI: 10.1002/Prot.23238  0.486
2012 Auclair SM, Bhanu MK, Kendall DA. Signal peptidase I: cleaving the way to mature proteins. Protein Science : a Publication of the Protein Society. 21: 13-25. PMID 22031009 DOI: 10.1002/Pro.757  0.771
2012 Kolayarattil MB, Auclair SM, Yu D, Kendall DA. Fluorescence Spectroscopy of Soluble E. Coli Spase I Demonstrates Conformational Changes Induced by Lipid and Signal Peptide Binding Biophysical Journal. 102: 403a. DOI: 10.1016/J.Bpj.2011.11.2203  0.797
2012 Wowor AJ, Auclair SM, Yu D, Zhao P, Kendall DA, Cole JL. The Dimer Interface of SecA Biophysical Journal. 102: 258a. DOI: 10.1016/J.Bpj.2011.11.1422  0.751
2011 Shim JY, Bertalovitz AC, Kendall DA. Identification of essential cannabinoid-binding domains: structural insights into early dynamic events in receptor activation. The Journal of Biological Chemistry. 286: 33422-35. PMID 21795705 DOI: 10.1074/Jbc.M111.261651  0.82
2011 Wowor AJ, Yu D, Kendall DA, Cole JL. Energetics of SecA dimerization. Journal of Molecular Biology. 408: 87-98. PMID 21315086 DOI: 10.1016/J.Jmb.2011.02.006  0.528
2011 Croke RL, Patil SM, Quevreaux J, Kendall DA, Alexandrescu AT. NMR determination of pKa values in α-synuclein. Protein Science : a Publication of the Protein Society. 20: 256-69. PMID 21280118 DOI: 10.1002/Pro.556  0.4
2011 Stadel R, Ahn KH, Kendall DA. The cannabinoid type-1 receptor carboxyl-terminus, more than just a tail. Journal of Neurochemistry. 117: 1-18. PMID 21244428 DOI: 10.1111/J.1471-4159.2011.07186.X  0.634
2011 Wowor AJ, Yu D, Kendall DA, Cole JL. Linkage Between SecA Dimerization and Ligand Binding Biophysical Journal. 100: 388a. DOI: 10.1016/J.Bpj.2010.12.2309  0.486
2010 Bertalovitz AC, Ahn KH, Kendall DA. Ligand Binding Sensitivity of the Extracellular Loop Two of the Cannabinoid Receptor 1. Drug Development Research. 71: 404-411. PMID 21170298 DOI: 10.1002/Ddr.20388  0.817
2010 Auclair SM, Moses JP, Musial-Siwek M, Kendall DA, Oliver DB, Mukerji I. Mapping of the signal peptide-binding domain of Escherichia coli SecA using Förster resonance energy transfer. Biochemistry. 49: 782-92. PMID 20025247 DOI: 10.1021/Bi901446R  0.786
2010 Ahn KH, Nishiyama A, Mierke DF, Kendall DA. Hydrophobic residues in helix 8 of cannabinoid receptor 1 are critical for structural and functional properties. Biochemistry. 49: 502-11. PMID 20025243 DOI: 10.1021/Bi901619R  0.679
2009 Ahn KH, Bertalovitz AC, Mierke DF, Kendall DA. Dual role of the second extracellular loop of the cannabinoid receptor 1: ligand binding and receptor localization. Molecular Pharmacology. 76: 833-42. PMID 19643997 DOI: 10.1124/Mol.109.057356  0.818
2009 Ahn KH, Pellegrini M, Tsomaia N, Yatawara AK, Kendall DA, Mierke DF. Structural analysis of the human cannabinoid receptor one carboxyl-terminus identifies two amphipathic helices. Biopolymers. 91: 565-73. PMID 19274719 DOI: 10.1002/Bip.21179  0.645
2008 Musial-Siwek M, Yeagle PL, Kendall DA. A small subset of signal peptidase residues are perturbed by signal peptide binding. Chemical Biology & Drug Design. 72: 140-6. PMID 18637988 DOI: 10.1111/J.1747-0285.2008.00685.X  0.821
2008 Musial-Siwek M, Kendall DA, Yeagle PL. Solution NMR of signal peptidase, a membrane protein. Biochimica Et Biophysica Acta. 1778: 937-44. PMID 18177734 DOI: 10.1016/J.Bbamem.2007.11.013  0.796
2007 Rusch SL, Kendall DA. Interactions that drive Sec-dependent bacterial protein transport. Biochemistry. 46: 9665-73. PMID 17676771 DOI: 10.1021/Bi7010064  0.405
2007 Sun C, Rusch SL, Kim J, Kendall DA. Chloroplast SecA and Escherichia coli SecA have distinct lipid and signal peptide preferences. Journal of Bacteriology. 189: 1171-5. PMID 17142391 DOI: 10.1128/Jb.01589-06  0.61
2007 Musial-Siwek M, Rusch SL, Kendall DA. Selective photoaffinity labeling identifies the signal peptide binding domain on SecA. Journal of Molecular Biology. 365: 637-48. PMID 17084862 DOI: 10.1016/J.Jmb.2006.10.027  0.82
2007 Rusch SL, Kendall DA. Oligomeric states of the SecA and SecYEG core components of the bacterial Sec translocon. Biochimica Et Biophysica Acta. 1768: 5-12. PMID 17011510 DOI: 10.1016/J.Bbamem.2006.08.013  0.344
2006 D'Antona AM, Ahn KH, Wang L, Mierke DF, Lucas-Lenard J, Kendall DA. A cannabinoid receptor 1 mutation proximal to the DRY motif results in constitutive activity and reveals intramolecular interactions involved in receptor activation. Brain Research. 1108: 1-11. PMID 16879811 DOI: 10.1016/J.Brainres.2006.05.042  0.811
2006 D'Antona AM, Ahn KH, Kendall DA. Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization. Biochemistry. 45: 5606-17. PMID 16634642 DOI: 10.1021/Bi060067K  0.797
2005 Musial-Siwek M, Rusch SL, Kendall DA. Probing the affinity of SecA for signal peptide in different environments. Biochemistry. 44: 13987-96. PMID 16229488 DOI: 10.1021/Bi050882K  0.817
2004 Wang L, Miller A, Rusch SL, Kendall DA. Demonstration of a specific Escherichia coli SecY-signal peptide interaction. Biochemistry. 43: 13185-92. PMID 15476412 DOI: 10.1021/Bi049485K  0.661
2004 Leggett JD, Aspley S, Beckett SR, D'Antona AM, Kendall DA, Kendall DA. Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid receptors. British Journal of Pharmacology. 141: 253-62. PMID 14707029 DOI: 10.1038/Sj.Bjp.0705607  0.754
2003 Bu Z, Wang L, Kendall DA. Nucleotide binding induces changes in the oligomeric state and conformation of Sec A in a lipid environment: a small-angle neutron-scattering study. Journal of Molecular Biology. 332: 23-30. PMID 12946344 DOI: 10.1016/S0022-2836(03)00840-4  0.589
2003 Andersson H, D'Antona AM, Kendall DA, Von Heijne G, Chin CN. Membrane assembly of the cannabinoid receptor 1: impact of a long N-terminal tail. Molecular Pharmacology. 64: 570-7. PMID 12920192 DOI: 10.1124/Mol.64.3.570  0.774
2003 Murphy JW, Kendall DA. Integrity of extracellular loop 1 of the human cannabinoid receptor 1 is critical for high-affinity binding of the ligand CP 55,940 but not SR 141716A. Biochemical Pharmacology. 65: 1623-31. PMID 12754098 DOI: 10.1016/S0006-2952(03)00155-2  0.508
2002 Ulfers AL, McMurry JL, Miller A, Wang L, Kendall DA, Mierke DF. Cannabinoid receptor-G protein interactions: G(alphai1)-bound structures of IC3 and a mutant with altered G protein specificity. Protein Science : a Publication of the Protein Society. 11: 2526-31. PMID 12237474 DOI: 10.1110/Ps.0218402  0.603
2002 Ulfers AL, McMurry JL, Kendall DA, Mierke DF. Structure of the third intracellular loop of the human cannabinoid 1 receptor. Biochemistry. 41: 11344-50. PMID 12234176 DOI: 10.1021/Bi0259610  0.41
2002 Rusch SL, Mascolo CL, Kebir MO, Kendall DA. Juxtaposition of signal-peptide charge and core region hydrophobicity is critical for functional signal peptides. Archives of Microbiology. 178: 306-10. PMID 12209265 DOI: 10.1007/S00203-002-0453-Z  0.441
2002 Kebir MO, Kendall DA. SecA specificity for different signal peptides. Biochemistry. 41: 5573-80. PMID 11969418 DOI: 10.1021/Bi015798T  0.48
2002 Miller A, Wang L, Kendall DA. SecB modulates the nucleotide-bound state of SecA and stimulates ATPase activity. Biochemistry. 41: 5325-32. PMID 11955083 DOI: 10.1021/Bi025639P  0.599
2001 Kim J, Rusch S, Luirink J, Kendall DA. Is Ffh required for export of secretory proteins? Febs Letters. 505: 245-8. PMID 11566184 DOI: 10.1016/S0014-5793(01)02784-3  0.607
2001 Kim J, Miller A, Wang L, Müller JP, Kendall DA. Evidence that SecB enhances the activity of SecA. Biochemistry. 40: 3674-80. PMID 11297435 DOI: 10.1021/Bi002617Z  0.718
2000 Kim J, Kendall DA. Sec-dependent protein export and the involvement of the molecular chaperone SecB. Cell Stress & Chaperones. 5: 267-75. PMID 11048650 DOI: 10.1379/1466-1268(2000)005<0267:Sdpeat>2.0.Co;2  0.523
2000 Kim J, Luirink J, Kendall DA. SecB dependence of an exported protein is a continuum influenced by the characteristics of the signal peptide or early mature region. Journal of Bacteriology. 182: 4108-12. PMID 10869093 DOI: 10.1128/Jb.182.14.4108-4112.2000  0.59
2000 Wang L, Miller A, Kendall DA. Signal peptide determinants of SecA binding and stimulation of ATPase activity. The Journal of Biological Chemistry. 275: 10154-9. PMID 10744698 DOI: 10.1074/Jbc.275.14.10154  0.658
1999 Abadji V, Lucas-Lenard JM, Chin C, Kendall DA. Involvement of the carboxyl terminus of the third intracellular loop of the cannabinoid CB1 receptor in constitutive activation of Gs. Journal of Neurochemistry. 72: 2032-8. PMID 10217281 DOI: 10.1046/J.1471-4159.1999.0722032.X  0.476
1999 McMurry JL, Kendall DA. An artificial transmembrane segment directs SecA, SecB, and electrochemical potential-dependent translocation of a long amino-terminal tail. The Journal of Biological Chemistry. 274: 6776-82. PMID 10037778 DOI: 10.1074/Jbc.274.10.6776  0.449
1998 Miller A, Wang L, Kendall DA. Synthetic signal peptides specifically recognize SecA and stimulate ATPase activity in the absence of preprotein. The Journal of Biological Chemistry. 273: 11409-12. PMID 9565549 DOI: 10.1074/Jbc.273.19.11409  0.631
1998 Kim J, Kendall DA. Identification of a sequence motif that confers SecB dependence on a SecB-independent secretory protein in vivo. Journal of Bacteriology. 180: 1396-401. PMID 9515905 DOI: 10.1128/Jb.180.6.1396-1401.1998  0.574
1998 Chin CN, Lucas-Lenard J, Abadji V, Kendall DA. Ligand binding and modulation of cyclic AMP levels depend on the chemical nature of residue 192 of the human cannabinoid receptor 1. Journal of Neurochemistry. 70: 366-73. PMID 9422383 DOI: 10.1046/J.1471-4159.1998.70010366.X  0.528
1997 Valent QA, de Gier JW, von Heijne G, Kendall DA, ten Hagen-Jongman CM, Oudega B, Luirink J. Nascent membrane and presecretory proteins synthesized in Escherichia coli associate with signal recognition particle and trigger factor. Molecular Microbiology. 25: 53-64. PMID 11902726 DOI: 10.1046/J.1365-2958.1997.4431808.X  0.398
1996 Chen H, Kim J, Kendall DA. Competition between functional signal peptides demonstrates variation in affinity for the secretion pathway. Journal of Bacteriology. 178: 6658-64. PMID 8955279 DOI: 10.1128/Jb.178.23.6658-6664.1996  0.619
1996 Izard JW, Rusch SL, Kendall DA. The amino-terminal charge and core region hydrophobicity interdependently contribute to the function of signal sequences. The Journal of Biological Chemistry. 271: 21579-82. PMID 8702945 DOI: 10.1074/Jbc.271.35.21579  0.358
1995 Rusch SL, Kendall DA. Protein transport via amino-terminal targeting sequences: common themes in diverse systems. Molecular Membrane Biology. 12: 295-307. PMID 8747274 DOI: 10.3109/09687689509072431  0.348
1995 Chen H, Kendall DA. Artificial transmembrane segments. Requirements for stop transfer and polypeptide orientation. The Journal of Biological Chemistry. 270: 14115-22. PMID 7775472 DOI: 10.1074/Jbc.270.23.14115  0.421
1995 Izard JW, Doughty MB, Kendall DA. Physical and conformational properties of synthetic idealized signal sequences parallel their biological function. Biochemistry. 34: 9904-12. PMID 7632690 DOI: 10.1021/Bi00031A012  0.435
1995 Valent QA, Kendall DA, High S, Kusters R, Oudega B, Luirink J. Early events in preprotein recognition in E. coli: interaction of SRP and trigger factor with nascent polypeptides. The Embo Journal. 14: 5494-5505. DOI: 10.1002/J.1460-2075.1995.Tb00236.X  0.401
1994 Rusch SL, Kendall DA. Transport of an export-defective protein by a highly hydrophobic signal peptide. The Journal of Biological Chemistry. 269: 1243-8. PMID 8288586  0.339
1994 Jain RG, Rusch SL, Kendall DA. Signal peptide cleavage regions. Functional limits on length and topological implications. The Journal of Biological Chemistry. 269: 16305-10. PMID 8206936  0.351
1994 Rusch SL, Chen H, Izard JW, Kendall DA. Signal peptide hydrophobicity is finely tailored for function. Journal of Cellular Biochemistry. 55: 209-17. PMID 8089196 DOI: 10.1002/Jcb.240550208  0.467
1994 Izard JW, Kendall DA. Signal peptides: exquisitely designed transport promoters. Molecular Microbiology. 13: 765-73. PMID 7815936 DOI: 10.1111/J.1365-2958.1994.Tb00469.X  0.449
1993 Doud SK, Chou MM, Kendall DA. Titration of protein transport activity by incremental changes in signal peptide hydrophobicity. Biochemistry. 32: 1251-6. PMID 8448135 DOI: 10.1021/Bi00056A008  0.463
1992 Rusch SL, Kendall DA. Signal sequences containing multiple aromatic residues. Journal of Molecular Biology. 224: 77-85. PMID 1548710 DOI: 10.1016/0022-2836(92)90577-7  0.465
1992 Matlin AR, Kendall DA, Carano KS, Banzon JA, Klecka SB, Solomon NM. Enhanced catalysis by active-site mutagenesis at aspartic acid 153 in Escherichia coli alkaline phosphatase. Biochemistry. 31: 8196-200. PMID 1525159 DOI: 10.1021/Bi00150A011  0.306
1991 Laforet GA, Kendall DA. Functional limits of conformation, hydrophobicity, and steric constraints in prokaryotic signal peptide cleavage regions. Wild type transport by a simple polymeric signal sequence. The Journal of Biological Chemistry. 266: 1326-34. PMID 1898733  0.33
1990 Kendall DA, Doud SK, Kaiser ET. A comparative analysis of single- and multiple-residue substitutions in the alkaline phosphatase signal peptide. Biopolymers. 29: 139-47. PMID 2183883 DOI: 10.1002/Bip.360290119  0.449
1990 Chou MM, Kendall DA. Polymeric sequences reveal a functional interrelationship between hydrophobicity and length of signal peptides. The Journal of Biological Chemistry. 265: 2873-80. PMID 2154463  0.35
1989 Laforet GA, Kaiser ET, Kendall DA. Signal peptide subsegments are not always functionally interchangeable. M13 procoat hydrophobic core fails to transport alkaline phosphatase in Escherichia coli. The Journal of Biological Chemistry. 264: 14478-85. PMID 2668291  0.358
1988 Butler-Ransohoff JE, Kendall DA, Kaiser ET. Use of site-directed mutagenesis to elucidate the role of arginine-166 in the catalytic mechanism of alkaline phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 85: 4276-8. PMID 3288990 DOI: 10.1073/Pnas.85.12.4276  0.318
1986 Kendall DA, Bock SC, Kaiser ET. Idealization of the hydrophobic segment of the alkaline phosphatase signal peptide. Nature. 321: 706-8. PMID 3520341 DOI: 10.1038/321706A0  0.447
1983 Womack MD, Kendall DA, MacDonald RC. Detergent effects on enzyme activity and solubilization of lipid bilayer membranes. Biochimica Et Biophysica Acta. 733: 210-5. PMID 6882760 DOI: 10.1016/0005-2736(83)90524-2  0.311
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