Year |
Citation |
Score |
2018 |
Betts A, Keunecke A, van Steeg TJ, van der Graaf PH, Avery LB, Jones H, Berkhout J. Linear pharmacokinetic parameters for monoclonal antibodies are similar within a species and across different pharmacological targets: A comparison between human, cynomolgus monkey and hFcRn Tg32 transgenic mouse using a population-modeling approach. Mabs. 1-55. PMID 29634430 DOI: 10.1080/19420862.2018.1462429 |
0.321 |
|
2017 |
Avery LB, Wade J, Wang M, Tam A, King A, Piche-Nicholas N, Kavosi MS, Penn S, Cirelli D, Kurz JC, Zhang M, Cunningham O, Jones R, Fennell BJ, McDonnell B, et al. Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics. Mabs. 0. PMID 29271699 DOI: 10.1080/19420862.2017.1417718 |
0.333 |
|
2016 |
Avery LB, Wang M, Kavosi MS, Joyce A, Kurz JC, Fan YY, Dowty ME, Zhang M, Zhang Y, Cheng A, Hua F, Jones HM, Neubert H, Polzer RJ, O'Hara DM. Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies. Mabs. 0. PMID 27232760 DOI: 10.1080/19420862.2016.1193660 |
0.367 |
|
2016 |
Fan YY, Avery LB, Wang M, O'Hara DM, Leung S, Neubert H. Tissue expression profile of human neonatal Fc receptor (FcRn) in Tg32 transgenic mice. Mabs. 0. PMID 27104806 DOI: 10.1080/19420862.2016.1178436 |
0.32 |
|
2014 |
Avery LB, Bumpus NN. Valproic acid is a novel activator of AMP-activated protein kinase and decreases liver mass, hepatic fat accumulation, and serum glucose in obese mice. Molecular Pharmacology. 85: 1-10. PMID 24105977 DOI: 10.1124/Mol.113.089755 |
0.303 |
|
2013 |
Lade JM, Avery LB, Bumpus NN. Human biotransformation of the nonnucleoside reverse transcriptase inhibitor rilpivirine and a cross-species metabolism comparison. Antimicrobial Agents and Chemotherapy. 57: 5067-79. PMID 23917319 DOI: 10.1128/Aac.01401-13 |
0.322 |
|
2013 |
Avery LB, Zarr MA, Bakshi RP, Siliciano RF, Hendrix CW. Increasing extracellular protein concentration reduces intracellular antiretroviral drug concentration and antiviral effect. Aids Research and Human Retroviruses. 29: 1434-42. PMID 23601085 DOI: 10.1089/Aid.2013.0031 |
0.598 |
|
2013 |
Avery LB, Sacktor N, McArthur JC, Hendrix CW. Protein-free efavirenz concentrations in cerebrospinal fluid and blood plasma are equivalent: applying the law of mass action to predict protein-free drug concentration. Antimicrobial Agents and Chemotherapy. 57: 1409-14. PMID 23295919 DOI: 10.1128/Aac.02329-12 |
0.621 |
|
2013 |
Avery LB, VanAusdall JL, Hendrix CW, Bumpus NN. Compartmentalization and antiviral effect of efavirenz metabolites in blood plasma, seminal plasma, and cerebrospinal fluid. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 422-9. PMID 23166317 DOI: 10.1124/Dmd.112.049601 |
0.573 |
|
2013 |
Avery LB, Sacktor N, McArthur JC, Hendrix C. Erratum: Protein-free efavirenz concentrations in cerebrospinal fluid andblood plasma are equivalent: Applying the law of mass action topredict protein-free drug concentration (Antimicrobial Agents and Chemotherapy (2013) 57:3 (1409-1414)) Antimicrobial Agents and Chemotherapy. 57. DOI: 10.1128/Aac.01250-13 |
0.585 |
|
2012 |
Tovar-y-Romo LB, Bumpus NN, Pomerantz D, Avery LB, Sacktor N, McArthur JC, Haughey NJ. Dendritic spine injury induced by the 8-hydroxy metabolite of efavirenz. The Journal of Pharmacology and Experimental Therapeutics. 343: 696-703. PMID 22984227 DOI: 10.1124/Jpet.112.195701 |
0.333 |
|
2011 |
Avery LB, Bakshi RP, Cao YJ, Hendrix CW. The male genital tract is not a pharmacological sanctuary from efavirenz. Clinical Pharmacology and Therapeutics. 90: 151-6. PMID 21633344 DOI: 10.1038/Clpt.2011.99 |
0.585 |
|
2010 |
Avery LB, Parsons TL, Meyers DJ, Hubbard WC. A highly sensitive ultra performance liquid chromatography-tandem mass spectrometric (UPLC-MS/MS) technique for quantitation of protein free and bound efavirenz (EFV) in human seminal and blood plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 3217-24. PMID 21036679 DOI: 10.1016/J.Jchromb.2010.09.011 |
0.37 |
|
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