Kathryn G. Eby, Ph.D. - Related publications

Affiliations: 
2010 Vanderbilt University, Nashville, TN 
Area:
Biochemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Zaarour RF, Azakir B, Hajam EY, Nawafleh H, Zeinelabdin NA, Engelsen AST, Thiery J, Jamora C, Chouaib S. Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival. Cancers. 13. PMID 33573362 DOI: 10.3390/cancers13030533   
2021 Boutelle AM, Attardi LD. p53 and Tumor Suppression: It Takes a Network. Trends in Cell Biology. PMID 33518400 DOI: 10.1016/j.tcb.2020.12.011   
2021 Xu Z, Wu W, Yan H, Hu Y, He Q, Luo P. Regulation of p53 stability as a therapeutic strategy for cancer. Biochemical Pharmacology. 114407. PMID 33421376 DOI: 10.1016/j.bcp.2021.114407   
2021 Demir Ö, Barros EP, Offutt TL, Rosenfeld M, Amaro RE. An integrated view of p53 dynamics, function, and reactivation. Current Opinion in Structural Biology. 67: 187-194. PMID 33401096 DOI: 10.1016/j.sbi.2020.11.005   
2021 Pang X, Zhang X, Jiang Y, Su Q, Li Q, Li Z. Autophagy: Mechanisms and Therapeutic Potential of Flavonoids in Cancer. Biomolecules. 11. PMID 33494431 DOI: 10.3390/biom11020135   
2021 Zhou JF, Zhou Q, Chen C, Pan JX. [A Review of the Roles of Endoplasmic Reticulum Stress in Cancer Cell Metastasis]. Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition. 52: 11-15. PMID 33474882 DOI: 10.12182/20210160503   
2021 Li Y, Cui K, Zhang Q, Li X, Lin X, Tang Y, Prochownik EV, Li Y. FBXL6 degrades phosphorylated p53 to promote tumor growth. Cell Death and Differentiation. PMID 33568778 DOI: 10.1038/s41418-021-00739-6   
2021 Han Q, Zhang C, Zhang Y, Li Y, Wu L, Sun X. Bufarenogin induces intrinsic apoptosis via Bax and ANT cooperation. Pharmacology Research & Perspectives. 9: e00694. PMID 33421322 DOI: 10.1002/prp2.694   
2021 Stewart-Ornstein J, Iwamoto Y, Miller MA, Prytyskach MA, Ferretti S, Holzer P, Kallen J, Furet P, Jambhekar A, Forrester WC, Weissleder R, Lahav G. p53 dynamics vary between tissues and are linked with radiation sensitivity. Nature Communications. 12: 898. PMID 33563973 DOI: 10.1038/s41467-021-21145-z   
2021 Tian X, Ahsan N, Lulla A, Lev A, Abbosh P, Dicker DT, Zhang S, El-Deiry WS. P53-independent partial restoration of the p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9. Neoplasia (New York, N.Y.). 23: 304-325. PMID 33582407 DOI: 10.1016/j.neo.2021.01.004   
2021 Wang X, Wang H, Xu J, Hou X, Zhan H, Zhen Y. Double-targeting CDCA8 and E2F1 inhibits the growth and migration of malignant glioma. Cell Death & Disease. 12: 146. PMID 33542211 DOI: 10.1038/s41419-021-03405-4   
2021 Mohapatra P, Shriwas O, Mohanty S, Ghosh A, Smita S, Kaushik SR, Arya R, Rath R, Das Majumdar S, Muduly DK, Raghav S, Nanda RK, Dash R. CMTM6 drives cisplatin resistance by regulating Wnt signaling through ENO-1/AKT/GSK3β axis. Jci Insight. PMID 33434185 DOI: 10.1172/jci.insight.143643   
2021 Wu C, Shu G, Huang H, Pang K, Yang X, Yang G. Methylgerambullin Derived From Plant Glyccsmis Pentaphylla (Retz) Correa. Mediates Anti-Hepatocellular Carcinoma Cancer Effect by Activating Mitochondrial and Endoplasmic Reticulum Stress Signaling and Inhibiting AKT and STAT3 Pathways. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 112031. PMID 33529679 DOI: 10.1016/j.fct.2021.112031   
2021 Bhat S, Kabekkodu SP, Adiga D, Fernandes R, Shukla V, Bhandari P, Pandey D, Sharan K, Satyamoorthy K. ZNF471 modulates EMT and functions as methylation regulated tumor suppressor with diagnostic and prognostic significance in cervical cancer. Cell Biology and Toxicology. PMID 33566221 DOI: 10.1007/s10565-021-09582-4   
2021 Kim Y, Park JB, Fukuda J, Watanabe M, Chun YS. The Effect of Neddylation Blockade on Slug-Dependent Cancer Cell Migration Is Regulated by p53 Mutation Status. Cancers. 13. PMID 33573293 DOI: 10.3390/cancers13030531   
2021 Turgu B, Zhang F, El-Naggar A, Negri GL, Kogler M, Tortola L, Johnson F, Ng T, Li A, Yapp D, Lockwood W, Martinez D, Maris JM, Daugaard M, Penninger JM, et al. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Oncogene. PMID 33603169 DOI: 10.1038/s41388-021-01680-1   
2021 Qin X, Liu J, Pan D, Ma W, Cheng P, Jin F. Corilagin induces human glioblastoma U251 cell apoptosis by impeding activity of (immuno)proteasome. Oncology Reports. 45. PMID 33649855 DOI: 10.3892/or.2021.7985   
2021 Park SK, Park S, Pentek C, Liebman SW. Tumor suppressor protein p53 expressed in yeast can remain diffuse, form a prion, or form unstable liquid-like droplets. Iscience. 24: 102000. PMID 33490908 DOI: 10.1016/j.isci.2020.102000   
2021 Xie H, Ma K, Zhang K, Zhou J, Li L, Yang W, Gong Y, Cai L, Gong K. Cell-cycle arrest and senescence in TP53-wild type renal carcinoma by enhancer RNA-P53-bound enhancer regions 2 (p53BER2) in a p53-dependent pathway. Cell Death & Disease. 12: 1. PMID 33414393 DOI: 10.1038/s41419-020-03229-8   
2021 Fletcher R, Tong J, Risnik D, Leibowitz BJ, Wang YJ, Concha-Benavente F, DeLiberty JM, Stolz DB, Pai RK, Ferris RL, Schoen RE, Yu J, Zhang L. Non-steroidal anti-inflammatory drugs induce immunogenic cell death in suppressing colorectal tumorigenesis. Oncogene. PMID 33603166 DOI: 10.1038/s41388-021-01687-8   
2021 Hu W, Wu C, Yuan C, Chen M, Jin C, Zheng C. Ethanol Extracted from Radix of Actinidia Chinensis Inhibits Human Colon Tumor Through Inhibiting Notch-signaling Pathway. Journal of Cancer. 12: 622-629. PMID 33403022 DOI: 10.7150/jca.51275   
2021 Nishibeppu K, Komatsu S, Kiuchi J, Kishimoto T, Takashima Y, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E. TRIM37 contributes to malignant outcomes and CDDP resistance in gastric cancer. Journal of Cancer. 12: 316-325. PMID 33391428 DOI: 10.7150/jca.47577   
2021 Wang L, Han H, Dong L, Wang Z, Qin Y. Function of p21 and its therapeutic effects in esophageal cancer. Oncology Letters. 21: 136. PMID 33552255 DOI: 10.3892/ol.2020.12397   
2021 Li CY, Lee SC, Lai WL, Chang KF, Huang XF, Hung PY, Lee CP, Hsieh MC, Tsai NM. Cell cycle arrest and apoptosis induction by extract in esophageal squamous cell carcinoma through activation of p53-induced apoptosis pathway. Food Science & Nutrition. 9: 1088-1098. PMID 33598192 DOI: 10.1002/fsn3.2084   
2021 Valente LJ, Attardi LD. P53 orchestrates a complex symphony of cellular processes during oncosuppression. Molecular & Cellular Oncology. 8: 1852066. PMID 33553606 DOI: 10.1080/23723556.2020.1852066   
2021 Fu X, Cui J, Meng X, Jiang P, Zheng Q, Zhao W, Chen X. Endoplasmic reticulum stress, cell death and tumor: Association between endoplasmic reticulum stress and the apoptosis pathway in tumors (Review). Oncology Reports. PMID 33469681 DOI: 10.3892/or.2021.7933   
2021 Liu S, Wang Y, Miao C, Xing Q, Wang Z. High expression of CDCA7 predicts poor prognosis for clear cell renal cell carcinoma and explores its associations with immunity. Cancer Cell International. 21: 140. PMID 33648519 DOI: 10.1186/s12935-021-01834-x   
2021 Wang L, Yang J, Wang HN, Fu RY, Liu XD, Piao YS, Wei LQ, Wang JW, Zhang L. LncRNA BCYRN1-induced autophagy enhances asparaginase resistance in extranodal NK/T-cell lymphoma. Theranostics. 11: 925-940. PMID 33391513 DOI: 10.7150/thno.46655   
2021 Wu M, Chen P, Liu F, Lv B, Ge M, Jiang P, Xu W, Liu X, Yang D. ONX0912, a selective oral proteasome inhibitor, triggering mitochondrial apoptosis and mitophagy in liver cancer. Biochemical and Biophysical Research Communications. 547: 102-110. PMID 33610037 DOI: 10.1016/j.bbrc.2021.02.037   
2021 Hu D, Yuan S, Zhong J, Liu Z, Wang Y, Liu L, Li J, Wen F, Liu J, Zhang J. Cellular senescence and hematological malignancies: From pathogenesis to therapeutics. Pharmacology & Therapeutics. 107817. PMID 33587950 DOI: 10.1016/j.pharmthera.2021.107817   
2021 Verma AK, Bharti PS, Rafat S, Bhatt D, Goyal Y, Pandey KK, Ranjan S, Almatroodi SA, Alsahli MA, Rahmani AH, Almatroudi A, Dev K. Autophagy Paradox of Cancer: Role, Regulation, and Duality. Oxidative Medicine and Cellular Longevity. 2021: 8832541. PMID 33628386 DOI: 10.1155/2021/8832541   
2021 Tang M, Zeng X, Luo J, Quan FF, Chen CY, Li YK, Liu J, Zhang QF. Gene commander in the trash heap: Transcriptional regulation and ubiquitination modification mediated by RNF6 in carcinogenesis. Experimental Cell Research. 112396. PMID 33485842 DOI: 10.1016/j.yexcr.2020.112396   
2021 An H, Heo JS, Kim P, Lian Z, Lee S, Park J, Hong E, Pang K, Park Y, Ooshima A, Lee J, Son M, Park H, Wu Z, Park KS, et al. Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells. Cell Death & Disease. 12: 159. PMID 33558527 DOI: 10.1038/s41419-021-03454-9   
2021 Choi YW, Kim YH, Oh SY, Suh KW, Kim YS, Lee GY, Yoon JE, Park SS, Lee YK, Park YJ, Kim HS, Park SH, Kim JH, Park TJ. Senescent Tumor Cells Build a Cytokine Shield in Colorectal Cancer. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 8: 2002497. PMID 33643790 DOI: 10.1002/advs.202002497   
2021 Jandova J, Hua AB, Fimbres J, Wondrak GT. Deuterium Oxide (DO) Induces Early Stress Response Gene Expression and Impairs Growth and Metastasis of Experimental Malignant Melanoma. Cancers. 13. PMID 33546433 DOI: 10.3390/cancers13040605   
2021 Kazimova T, Tschanz F, Sharma A, Telarovic I, Wachtel M, Pedot G, Schafer B, Pruschy MN. Paracrine placental growth factor signaling in response to ionizing radiation is p53-dependent and contributes to radioresistance. Molecular Cancer Research : McR. PMID 33619227 DOI: 10.1158/1541-7786.MCR-20-0403   
2021 Islam MS, Rahi MS, Jahangir CA, Jerin I, Hasan MM, Hoque KMF, Reza MA. Deciphering the molecular pathways of apoptosis using purified fractions from leaf extract of Basella alba through studying the regulation of apoptosis related genes. Molecular Biology Reports. PMID 33454909 DOI: 10.1007/s11033-021-06136-z   
2021 Liu S, Aweya JJ, Zheng L, Zheng Z, Huang H, Wang F, Yao D, Ou T, Zhang Y. LvHemB1, a novel cationic antimicrobial peptide derived from the hemocyanin of Litopenaeus vannamei, induces cancer cell death by targeting mitochondrial voltage-dependent anion channel 1. Cell Biology and Toxicology. PMID 33630204 DOI: 10.1007/s10565-021-09588-y   
2021 Mrouj K, Andrés-Sánchez N, Dubra G, Singh P, Sobecki M, Chahar D, Al Ghoul E, Aznar AB, Prieto S, Pirot N, Bernex F, Bordignon B, Hassen-Khodja C, Villalba M, Krasinska L, et al. Ki-67 regulates global gene expression and promotes sequential stages of carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33658388 DOI: 10.1073/pnas.2026507118   
2021 Perrotta RM, Bach CA, Salatino M, Rabinovich GA. Reprogramming the tumor metastasis cascade by targeting galectin-driven networks. The Biochemical Journal. 478: 597-617. PMID 33600595 DOI: 10.1042/BCJ20200167   
2021 Xie S, Fan W, Yang C, Lei W, Pan H, Tong X, Wu Y, Wang S. Beclin1‑armed oncolytic Vaccinia virus enhances the therapeutic efficacy of R‑CHOP against lymphoma in vitro and in vivo. Oncology Reports. PMID 33469679 DOI: 10.3892/or.2021.7942   
2021 Grayson KA, Hope JM, Wang W, Reinhart-King CA, King MR. Taxanes Sensitize Prostate Cancer Cells to TRAIL-Induced Apoptotic Synergy via Endoplasmic Reticulum Stress. Molecular Cancer Therapeutics. PMID 33632873 DOI: 10.1158/1535-7163.MCT-20-0495   
2021 Zhang Z, Feng X, Deng Z, Cheng J, Wang Y, Zhao M, Zhao Y, He S, Huang Q. Irradiation-induced polyploid giant cancer cells are involved in tumor cell repopulation via neosis. Molecular Oncology. PMID 33523579 DOI: 10.1002/1878-0261.12913   
2021 Zhang Z, Feng X, Deng Z, Cheng J, Wang Y, Zhao M, Zhao Y, He S, Huang Q. Irradiation-induced polyploid giant cancer cells are involved in tumor cell repopulation via neosis. Molecular Oncology. PMID 33523579 DOI: 10.1002/1878-0261.12913   
2021 Fujimoto M, Kamiyama M, Fuse K, Ryuno H, Odawara T, Furukawa N, Yoshimatsu Y, Watabe T, Prchal-Murphy M, Sexl V, Tahara H, Hayakawa Y, Sato T, Takeda K, Naguro I, et al. ASK1 suppresses NK cell-mediated intravascular tumor cell clearance in lung metastasis. Cancer Science. PMID 33565179 DOI: 10.1111/cas.14842   
2021 Vasilikos L, Hänggi K, Spilgies LM, Kisele S, Rufli S, Wong WW. Loss of cIAP1 in Endothelial Cells Limits Metastatic Extravasation through Tumor-Derived Lymphotoxin Alpha. Cancers. 13. PMID 33546280 DOI: 10.3390/cancers13040599   
2021 Mathewson ND, Ashenberg O, Tirosh I, Gritsch S, Perez EM, Marx S, Jerby-Arnon L, Chanoch-Myers R, Hara T, Richman AR, Ito Y, Pyrdol J, Friedrich M, Schumann K, Poitras MJ, et al. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis. Cell. PMID 33592174 DOI: 10.1016/j.cell.2021.01.022   
2021 Assabban A, Dubois-Vedrenne I, Van Maele L, Salcedo R, Snyder BL, Zhou L, Azouz A, de Toeuf B, Lapouge G, La C, Melchior M, Nguyen M, Thomas S, Wu SF, Hu W, et al. Tristetraprolin expression by keratinocytes protects against skin carcinogenesis. Jci Insight. PMID 33497366 DOI: 10.1172/jci.insight.140669   
2021 Pierce SE, Kim SH, Greenleaf WJ. Finding needles in a haystack: dissecting tumor heterogeneity with single-cell transcriptomic and chromatin accessibility profiling. Current Opinion in Genetics & Development. 66: 36-40. PMID 33418426 DOI: 10.1016/j.gde.2020.11.008   
2021 Ray SK, Mukherjee S. Mitophagy in Carcinogenesis and Tumor progression- A New paradigm with Emerging Importance. Anti-Cancer Agents in Medicinal Chemistry. PMID 33438558 DOI: 10.2174/1871520621666210112121910