Mary E. Pacold, Ph.D. - Publications

Affiliations: 
2010 Bioinformatics University of California, San Diego, La Jolla, CA 
Area:
Virology Biology, Bioinformatics Biology

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, Cho S, Freinkman E, Birsoy K, Abu-Remaileh M, Shaul YD, et al. A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. Nature Chemical Biology. PMID 27110680 DOI: 10.1038/Nchembio.2070  0.01
2015 Saxton RA, Knockenhauer KE, Wolfson RL, Chantranupong L, Pacold ME, Wang T, Schwartz TU, Sabatini DM. Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway. Science (New York, N.Y.). PMID 26586190 DOI: 10.1126/Science.Aad2087  0.01
2015 Kim D, Fiske BP, Birsoy K, Freinkman E, Kami K, Possemato RL, Chudnovsky Y, Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M, Ramkissoon SH, Ligon KL, et al. SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. Nature. 520: 363-7. PMID 25855294 DOI: 10.1038/Nature14363  0.01
2014 Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, et al. Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition. Cell. 158: 1094-109. PMID 25171410 DOI: 10.1016/J.Cell.2014.07.032  0.01
2014 Schwartz S, Mumbach MR, Jovanovic M, Wang T, Maciag K, Bushkin GG, Mertins P, Ter-Ovanesyan D, Habib N, Cacchiarelli D, Sanjana NE, Freinkman E, Pacold ME, Satija R, Mikkelsen TS, et al. Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Reports. 8: 284-96. PMID 24981863 DOI: 10.1016/J.Celrep.2014.05.048  0.01
2014 Wagner GA, Pacold ME, Kosakovsky Pond SL, Caballero G, Chaillon A, Rudolph AE, Morris SR, Little SJ, Richman DD, Smith DM. Incidence and prevalence of intrasubtype HIV-1 dual infection in at-risk men in the United States. The Journal of Infectious Diseases. 209: 1032-8. PMID 24273040 DOI: 10.1093/Infdis/Jit633  0.44
2014 Lim SM, Westover KD, Ficarro SB, Harrison RA, Choi HG, Pacold ME, Carrasco M, Hunter J, Kim ND, Xie T, Sim T, Jänne PA, Meyerson M, Marto JA, Engen JR, et al. Therapeutic targeting of oncogenic K-Ras by a covalent catalytic site inhibitor. Angewandte Chemie (International Ed. in English). 53: 199-204. PMID 24259466 DOI: 10.1002/Anie.201307387  0.01
2013 Chaillon A, Wagner GA, Hepler NL, Little SJ, Kosakovsky Pond SL, Caballero G, Pacold ME, Phung P, Wrin T, Richman DD, Wertheim JO, Smith DM. Dynamics of viral evolution and neutralizing antibody response after HIV-1 superinfection. Journal of Virology. 87: 12737-44. PMID 24049166 DOI: 10.1128/Jvi.02260-13  0.44
2013 Kang SA, Pacold ME, Cervantes CL, Lim D, Lou HJ, Ottina K, Gray NS, Turk BE, Yaffe MB, Sabatini DM. mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin. Science (New York, N.Y.). 341: 1236566. PMID 23888043 DOI: 10.1126/Science.1236566  0.01
2013 Hightower GK, May SJ, Pérez-Santiago J, Pacold ME, Wagner GA, Little SJ, Richman DD, Mehta SR, Smith DM, Pond SL. HIV-1 clade B pol evolution following primary infection. Plos One. 8: e68188. PMID 23840830 DOI: 10.1371/Journal.Pone.0068188  0.44
2013 Floyd SR, Pacold ME, Huang Q, Clarke SM, Lam FC, Cannell IG, Bryson BD, Rameseder J, Lee MJ, Blake EJ, Fydrych A, Ho R, Greenberger BA, Chen GC, Maffa A, et al. The bromodomain protein Brd4 insulates chromatin from DNA damage signalling. Nature. 498: 246-50. PMID 23728299 DOI: 10.1038/Nature12147  0.01
2013 Wagner GA, Pacold ME, Vigil E, Caballero G, Morris SR, Kosakovsky Pond SL, Little SJ, Richman DD, Gianella S, Smith DM. Using ultradeep pyrosequencing to study HIV-1 coreceptor usage in primary and dual infection. The Journal of Infectious Diseases. 208: 271-4. PMID 23599311 DOI: 10.1093/Infdis/Jit168  0.44
2013 Babrzadeh F, Varghese V, Pacold M, Liu TF, Nyrén P, Schiffer C, Fessel WJ, Shafer RW. Collinearity of protease mutations in HIV-1 samples with high-level protease inhibitor class resistance Journal of Antimicrobial Chemotherapy. 68: 414-418. PMID 23085775 DOI: 10.1093/Jac/Dks409  0.44
2012 Karve S, Werner ME, Sukumar R, Cummings ND, Copp JA, Wang EC, Li C, Sethi M, Chen RC, Pacold ME, Wang AZ. Revival of the abandoned therapeutic wortmannin by nanoparticle drug delivery. Proceedings of the National Academy of Sciences of the United States of America. 109: 8230-5. PMID 22547809 DOI: 10.1073/Pnas.1120508109  0.01
2012 Pacold ME, Pond SL, Wagner GA, Delport W, Bourque DL, Richman DD, Little SJ, Smith DM. Clinical, virologic, and immunologic correlates of HIV-1 intraclade B dual infection among men who have sex with men. Aids (London, England). 26: 157-65. PMID 22045341 DOI: 10.1097/Qad.0B013E32834Dcd26  0.44
2011 Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, et al. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature. 476: 346-50. PMID 21760589 DOI: 10.1038/Nature10350  0.01
2011 Gianella S, Delport W, Pacold ME, Young JA, Choi JY, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM. Detection of minority resistance during early HIV-1 infection: natural variation and spurious detection rather than transmission and evolution of multiple viral variants. Journal of Virology. 85: 8359-67. PMID 21632754 DOI: 10.1128/Jvi.02582-10  0.44
2010 Pacold M, Smith D, Little S, Cheng PM, Jordan P, Ignacio C, Richman D, Pond SK. Comparison of methods to detect HIV dual infection. Aids Research and Human Retroviruses. 26: 1291-8. PMID 20954840 DOI: 10.1089/Aid.2010.0042  0.32
2010 Manosuthi W, Butler DM, Pérez-Santiago J, Poon AF, Pillai SK, Mehta SR, Pacold ME, Richman DD, Pond SK, Smith DM. Protease polymorphisms in HIV-1 subtype CRF01_AE represent selection by antiretroviral therapy and host immune pressure. Aids (London, England). 24: 411-6. PMID 20009919 DOI: 10.1097/Qad.0B013E3283350Eef  0.44
2009 Butler DM, Pacold ME, Jordan PS, Richman DD, Smith DM. The efficiency of single genome amplification and sequencing is improved by quantitation and use of a bioinformatics tool. Journal of Virological Methods. 162: 280-3. PMID 19698751 DOI: 10.1016/J.Jviromet.2009.08.002  0.44
2009 Smith DM, May SJ, Tweeten S, Drumright L, Pacold ME, Kosakovsky Pond SL, Pesano RL, Lie YS, Richman DD, Frost SD, Woelk CH, Little SJ. A public health model for the molecular surveillance of HIV transmission in San Diego, California. Aids (London, England). 23: 225-32. PMID 19098493 DOI: 10.1097/Qad.0B013E32831D2A81  0.44
2008 Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L. Slow self-activation enhances the potency of viridin prodrugs. Journal of Medicinal Chemistry. 51: 4699-707. PMID 18630894 DOI: 10.1021/Jm800374F  0.01
2008 Cachay ER, Frost SD, Poon AF, Looney D, Rostami SM, Pacold ME, Richman DD, Little SJ, Smith DM. Herpes simplex virus type 2 acquisition during recent HIV infection does not influence plasma HIV levels. Journal of Acquired Immune Deficiency Syndromes (1999). 47: 592-6. PMID 18197122 DOI: 10.1097/Qai.0B013E318163Bd87  0.44
2007 Tseng TT, McMahon AM, Johnson VT, Mangubat EZ, Zahm RJ, Pacold ME, Jakobsson E. Sodium channel auxiliary subunits. Journal of Molecular Microbiology and Biotechnology. 12: 249-62. PMID 17587873 DOI: 10.1159/000099646  0.44
2006 Tseng TT, McMahon AM, Zahm RJ, Pacold ME, Jakobsson E. Calcium channel auxiliary subunits. Journal of Molecular Microbiology and Biotechnology. 11: 326-44. PMID 17114897 DOI: 10.1159/000095635  0.44
2004 Misaghi S, Pacold ME, Blom D, Ploegh HL, Korbel GA. Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover. Chemistry & Biology. 11: 1677-87. PMID 15610852 DOI: 10.1016/J.Chembiol.2004.11.010  0.01
2004 Perisic O, Wilson MI, Karathanassis D, Bravo J, Pacold ME, Ellson CD, Hawkins PT, Stephens L, Williams RL. The role of phosphoinositides and phosphorylation in regulation of NADPH oxidase. Advances in Enzyme Regulation. 44: 279-98. PMID 15581496 DOI: 10.1016/J.Advenzreg.2003.11.003  0.01
2004 Hirsch C, Misaghi S, Blom D, Pacold ME, Ploegh HL. Yeast N-glycanase distinguishes between native and non-native glycoproteins Embo Reports. 5: 201-206. PMID 14726951 DOI: 10.1038/Sj.Embor.7400066  0.01
2002 Ma Y, Greener T, Pacold ME, Kaushal S, Greene LE, Eisenberg E. Identification of domain required for catalytic activity of auxilin in supporting clathrin uncoating by Hsc70. The Journal of Biological Chemistry. 277: 49267-74. PMID 12377777 DOI: 10.1074/jbc.M203695200  0.01
2001 Bravo J, Karathanassis D, Pacold CM, Pacold ME, Ellson CD, Anderson KE, Butler PJ, Lavenir I, Perisic O, Hawkins PT, Stephens L, Williams RL. The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate. Molecular Cell. 8: 829-39. PMID 11684018 DOI: 10.1016/S1097-2765(01)00372-0  0.01
2001 Clapier CR, De Boer J, Pacold ME, Tamme R, Van Dinten LC. Brakes and gas pedals. Meeting: Spetses 2000, molecular mechanisms of development and disease Embo Reports. 2: 563-567. PMID 11463738 DOI: 10.1093/embo-reports/kve140  0.01
2000 Pacold ME, Suire S, Perisic O, Lara-Gonzalez S, Davis CT, Walker EH, Hawkins PT, Stephens L, Eccleston JF, Williams RL. Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma. Cell. 103: 931-43. PMID 11136978 DOI: 10.1016/S0092-8674(00)00196-3  0.01
2000 Walker EH, Pacold ME, Perisic O, Stephens L, Hawkins PT, Wymann MP, Williams RL. Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine. Molecular Cell. 6: 909-19. PMID 11090628 DOI: 10.1016/S1097-2765(05)00089-4  0.01
1995 Pacold ME, Stevens FJ, Li D, Anderson LE. The NADP-linked glyceraldehyde-3-phosphate dehydrogenases of Anabaena variabilis and Synechocystis PCC 6803, which lack one of the cysteines found in the higher plant enzyme, are not reductively activated Photosynthesis Research. 43: 125-130. DOI: 10.1007/BF00042969  0.01
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