| Year |
Citation |
Score |
| 2024 |
Nikodijević O, Jacobson KA, Daly JW. Effects of Combinations of Methylxanthines and Adenosine Analogs on Locomotor Activity in Control and Chronic Caffeine-Treated Mice. Drug Development Research. 30: 104-110. PMID 38250653 DOI: 10.1002/ddr.430300209 |
0.338 |
|
| 2010 |
Fitch RW, Spande TF, Garraffo HM, Yeh HJ, Daly JW. Phantasmidine: an epibatidine congener from the ecuadorian poison frog Epipedobates anthonyi. Journal of Natural Products. 73: 331-7. PMID 20337496 DOI: 10.1021/Np900727E |
0.306 |
|
| 2009 |
Fitch RW, Sturgeon GD, Patel SR, Spande TF, Garraffo HM, Daly JW, Blaauw RH. Epiquinamide: a poison that wasn't from a frog that was. Journal of Natural Products. 72: 243-7. PMID 19245264 DOI: 10.1021/Np8005452 |
0.323 |
|
| 2009 |
Fitch RW, Spande TF, Garraffo HM, Chase RR, Clinedinst MA, Parkes DA, Reed R, Whittaker NF, Daly JW. Dioicine: A novel prenylated purine alkaloid from Gymnocladus dioicus Heterocycles. 79: 583-598. DOI: 10.3987/Com-08-S(D)19 |
0.306 |
|
| 2007 |
Kobayashi S, Toyooka N, Zhou D, Tsuneki H, Wada T, Sasaoka T, Sakai H, Nemoto H, Garraffo HM, Spande TF, Daly JW. Flexible synthesis of poison-frog alkaloids of the 5,8-disubstituted indolizidine-class. II: Synthesis of (-)-209B, (-)-231C, (-)-233D, (-)-235B", (-)-221I, and an epimer of 193E and pharmacological effects at neuronal nicotinic acetylcholine receptors. Beilstein Journal of Organic Chemistry. 3: 30. PMID 21931443 DOI: 10.1186/1860-5397-3-30 |
0.316 |
|
| 2007 |
Toyooka N, Kobayashi S, Zhou D, Tsuneki H, Wada T, Sakai H, Nemoto H, Sasaoka T, Garraffo HM, Spande TF, Daly JW. Synthesis of poison-frog alkaloids 233A, 235U, and 251AA and their inhibitory effects on neuronal nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry Letters. 17: 5872-5. PMID 17827002 DOI: 10.1016/J.Bmcl.2007.08.045 |
0.307 |
|
| 2006 |
Dismukes K, Rogers M, Daly JW. CYCLIC ADENOSINE 3′,5′-MONOPHOSPHATE FORMATION IN GUINEA-PIG BRAIN SLICES: EFFECT OF H1- AND H2-HISTAMINERGIC AGONISTS Journal of Neurochemistry. 26: 785-790. DOI: 10.1111/J.1471-4159.1976.Tb04451.X-I1 |
0.339 |
|
| 2005 |
Fitch RW, Kaneko Y, Klaperski P, Daly JW, Seitz G, Gündisch D. Halogenated and isosteric cytisine derivatives with increased affinity and functional activity at nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry Letters. 15: 1221-4. PMID 15686946 DOI: 10.1016/J.Bmcl.2004.11.073 |
0.31 |
|
| 2004 |
Fitch RW, Pei XF, Kaneko Y, Gupta T, Shi D, Federova I, Daly JW. Homoepiboxidines: further potent agonists for nicotinic receptors. Bioorganic & Medicinal Chemistry. 12: 179-90. PMID 14697783 DOI: 10.1016/J.Bmc.2003.10.015 |
0.317 |
|
| 2003 |
Shi D, Padgett WL, Daly JW. Caffeine analogs: effects on ryanodine-sensitive calcium-release channels and GABAA receptors. Cellular and Molecular Neurobiology. 23: 331-47. PMID 12825831 DOI: 10.1023/A:1023688604792 |
0.332 |
|
| 2003 |
Harper JL, Camerini-Otero CS, Li AH, Kim SA, Jacobson KA, Daly JW. Dihydropyridines as inhibitors of capacitative calcium entry in leukemic HL-60 cells. Biochemical Pharmacology. 65: 329-38. PMID 12527326 DOI: 10.1016/S0006-2952(02)01488-0 |
0.423 |
|
| 2002 |
Sei Y, Brandom BW, Bina S, Hosoi E, Gallagher KL, Wyre HW, Pudimat PA, Holman SJ, Venzon DJ, Daly JW, Muldoon S. Patients with malignant hyperthermia demonstrate an altered calcium control mechanism in B lymphocytes. Anesthesiology. 97: 1052-8. PMID 12411786 DOI: 10.1097/00000542-200211000-00005 |
0.491 |
|
| 2002 |
Müller CE, Thorand M, Qurishi R, Diekmann M, Jacobson KA, Padgett WL, Daly JW. Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. Journal of Medicinal Chemistry. 45: 3440-50. PMID 12139454 DOI: 10.1021/Jm011093D |
0.488 |
|
| 2002 |
Hayallah AM, Sandoval-RamÃrez J, Reith U, Schobert U, Preiss B, Schumacher B, Daly JW, Müller CE. 1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists. Journal of Medicinal Chemistry. 45: 1500-10. PMID 11906291 DOI: 10.1021/Jm011049Y |
0.326 |
|
| 2001 |
Sei Y, Gallagher KL, Daly JW. Multiple effects of caffeine on Ca2+ release and influx in human B lymphocytes. Cell Calcium. 29: 149-60. PMID 11162852 DOI: 10.1054/Ceca.2000.0175 |
0.508 |
|
| 2000 |
Jiang X, Lim LY, Daly JW, Li AH, Jacobson KA, Roberge M. Structure-activity relationships for G2 checkpoint inhibition by caffeine analogs. International Journal of Oncology. 16: 971-8. PMID 10762633 DOI: 10.3892/Ijo.16.5.971 |
0.343 |
|
| 1998 |
Park KS, Hoffmann C, Kim HO, Padgett WL, Daly JW, Brambilla R, Motta C, Abbracchio MP, Jacobson KA. Activation and Desensitization of Rat A3-Adenosine Receptors by Selective Adenosine Derivatives and Xanthine-7-Ribosides. Drug Development Research. 44: 97-105. PMID 23487508 DOI: 10.1002/(Sici)1098-2299(199806/07)44:2/3<97::Aid-Ddr7>3.0.Co;2-5 |
0.487 |
|
| 1998 |
CREVELING CR, DALY JW, WITKOP B, UNDENFRIEND S. Substrates and inhibitors of dopamine-beta-oxidase. Biochimica Et Biophysica Acta. 64: 125-34. PMID 14023834 DOI: 10.1016/0006-3002(62)90765-5 |
0.483 |
|
| 1998 |
DALY J, AXELROD J, WITKOP B. Methylation and demethylation in relation to the in vitro metabolism of mescaline. Annals of the New York Academy of Sciences. 96: 37-43. PMID 13883261 DOI: 10.1111/J.1749-6632.1962.Tb50099.X |
0.553 |
|
| 1998 |
UDENFRIEND S, CREVELING CR, POSNER H, REDFIELD BG, DALY J, WITKOP B. On the inability of tryptamine to serve as a precursor of serotonin. Archives of Biochemistry and Biophysics. 83: 501-7. PMID 13855159 DOI: 10.1016/0003-9861(59)90058-X |
0.461 |
|
| 1998 |
UDENFRIEND S, CREVELING CR, OZAKI M, DALY JW, WITKOP B. Inhibitors of norepinephrine metabolism in vivo. Archives of Biochemistry and Biophysics. 84: 249-51. PMID 13840157 DOI: 10.1016/0003-9861(59)90577-6 |
0.456 |
|
| 1997 |
Daly JW, Shi D, Padgett WL, Ji XD, Jacobson KA. Riboflavin: Inhibitory Effects on Receptors, G-Proteins, and Adenylate Cyclase. Drug Development Research. 42: 98-108. PMID 22772360 DOI: 10.1002/(Sici)1098-2299(199710)42:2<98::Aid-Ddr6>3.0.Co;2-K |
0.468 |
|
| 1997 |
Badio B, Garraffo HM, Padgett WL, Greig NH, Daly JW. Pseudophrynaminol: a potent noncompetitive blocker of nicotinic receptor-channels. Biochemical Pharmacology. 53: 671-6. PMID 9113086 DOI: 10.1016/S0006-2952(96)00878-7 |
0.311 |
|
| 1997 |
Badio B, Garraffo HM, Plummer CV, Padgett WL, Daly JW. Synthesis and nicotinic activity of epiboxidine: an isoxazole analogue of epibatidine. European Journal of Pharmacology. 321: 189-94. PMID 9063687 DOI: 10.1016/S0014-2999(96)00939-9 |
0.307 |
|
| 1996 |
Siddiqi SM, Ji XD, Melman N, Olah ME, Jain R, Evans P, Glashofer M, Padgett WL, Cohen LA, Daly JW, Stiles GL, Jacobson KA. A SURVEY OF NONXANTHINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS. Nucleosides & Nucleotides. 15: 693-717. PMID 27043138 DOI: 10.1080/07328319608002416 |
0.49 |
|
| 1996 |
Shin Y, Daly JW, Jacobson KA. Activation of Phosphoinositide Breakdown and Elevation of Intracellular Calcium in a Rat RBL-2H3 Mast Cell Line by Adenosine Analogs: Involvement of A(3)-Adenosine Receptors? Drug Development Research. 39: 36-46. PMID 23087534 DOI: 10.1002/(Sici)1098-2299(19960901)39:1<36::Aid-Ddr5>3.0.Co;2-L |
0.487 |
|
| 1996 |
DALY J, INSCOE JK, AXELROD J. THE FORMATION OF O-METHYLATED CATECHOLS BY MICROSOMAL HYDROXYLATION OF PHENOLS AND SUBSEQUENT ENZYMATIC CATECHOL O-METHYLATION. SUBSTRATE SPECIFICITY. Journal of Medicinal Chemistry. 8: 153-7. PMID 14332654 DOI: 10.1021/Jm00326A003 |
0.419 |
|
| 1996 |
Jacobson KA, von Lubitz DK, Daly JW, Fredholm BB. Adenosine receptor ligands: differences with acute versus chronic treatment. Trends in Pharmacological Sciences. 17: 108-13. PMID 8936347 DOI: 10.1016/0165-6147(96)10002-X |
0.352 |
|
| 1996 |
Badio B, Shi D, Shin Y, Hutchinson KD, Padgett WL, Daly JW. Spiropyrrolizidines: a new class of blockers of nicotinic receptors. Biochemical Pharmacology. 52: 933-9. PMID 8781513 DOI: 10.1016/0006-2952(96)00464-9 |
0.315 |
|
| 1996 |
van Rhee AM, Siddiqi SM, Melman N, Shi D, Padgett WL, Daly JW, Jacobson KA. Tetrahydrobenzothiophenone derivatives as a novel class of adenosine receptor antagonists. Journal of Medicinal Chemistry. 39: 398-406. PMID 8558508 DOI: 10.1021/Jm9504823 |
0.508 |
|
| 1996 |
Shin Y, Daly JW, Jacobson KA. Activation of phosphoinositide breakdown and elevation of intracellular calcium in a rat RBL-2H3 mast cell line by adenosine analogs: Involvement of A3-adenosine receptors? Drug Development Research. 39: 36-46. DOI: 10.1002/(SICI)1098-2299(19960901)39:1<36::AID-DDR5>3.0.CO;2-L |
0.399 |
|
| 1995 |
Moni RW, Romero FS, Daly JW. The amphiphilic peptide adenoregulin enhances agonist binding to A1-adenosine receptors and [35S]GTP gamma S to brain membranes. Cellular and Molecular Neurobiology. 15: 465-93. PMID 8565049 DOI: 10.1007/Bf02071881 |
0.354 |
|
| 1995 |
Von Lubitz DK, Kim J, Beenhakker M, Carter MF, Lin RC, Meshulam Y, Daly JW, Shi D, Zhou LM, Jacobson KA. Chronic NMDA receptor stimulation: therapeutic implications of its effect on adenosine A1 receptors. European Journal of Pharmacology. 283: 185-92. PMID 7498308 DOI: 10.1016/0014-2999(95)00338-L |
0.413 |
|
| 1994 |
Daly JW, Shi D, Nikodijevic O, Jacobson KA. The role of adenosine receptors in the central action of caffeine. Pharmacopsychoecologia. 7: 201-213. PMID 25821357 |
0.395 |
|
| 1994 |
Brackett LE, Daly JW. Functional characterization of the A2b adenosine receptor in NIH 3T3 fibroblasts. Biochemical Pharmacology. 47: 801-14. PMID 8135856 DOI: 10.1016/0006-2952(94)90480-4 |
0.314 |
|
| 1994 |
Nikodijevic B, Sei Y, Shin Y, Daly JW. Effects of ATP and UTP in pheochromocytoma PC12 cells: evidence for the presence of three P2 receptors, only one of which subserves stimulation of norepinephrine release. Cellular and Molecular Neurobiology. 14: 27-47. PMID 7954659 DOI: 10.1007/Bf02088587 |
0.536 |
|
| 1994 |
Shi D, Nikodijević O, Jacobson KA, Daly JW. Effects of chronic caffeine on adenosine, dopamine and acetylcholine systems in mice. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 328: 261-87. PMID 7625882 |
0.361 |
|
| 1993 |
Jacobson KA, Nikodijević O, Padgett WL, Gallo-Rodriguez C, Maillard M, Daly JW. 8-(3-Chlorostyryl)caffeine (CSC) is a selective A2-adenosine antagonist in vitro and in vivo. Febs Letters. 323: 141-4. PMID 8495727 DOI: 10.1016/0014-5793(93)81466-D |
0.476 |
|
| 1993 |
Daly JW, Padgett WL, Secunda SI, Thompson RD, Olsson RA. Structure-activity relationships for 2-substituted adenosines at A1 and A2 adenosine receptors. Pharmacology. 46: 91-100. PMID 8441759 DOI: 10.1159/000139033 |
0.351 |
|
| 1993 |
Jacobson KA, Shi D, Gallo-Rodriguez C, Manning M, Müller C, Daly JW, Neumeyer JL, Kiriasis L, Pfleiderer W. Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. Journal of Medicinal Chemistry. 36: 2639-44. PMID 8410976 DOI: 10.1021/Jm00070A007 |
0.478 |
|
| 1993 |
Jacobson KA, Nikodijević O, Shi D, Gallo-Rodriguez C, Olah ME, Stiles GL, Daly JW. A role for central A3-adenosine receptors. Mediation of behavioral depressant effects. Febs Letters. 336: 57-60. PMID 8262217 DOI: 10.1016/0014-5793(93)81608-3 |
0.47 |
|
| 1993 |
Chen GT, King M, Gusovsky F, Creveling CR, Daly JW, Chen BH, Nie JY, Kirk KL. Syntheses of 2,5- and 2,6-difluoronorepinephrine, 2,5-difluoroepinephrine, and 2,6-difluorophenylephrine: effect of disubstitution with fluorine on adrenergic activity. Journal of Medicinal Chemistry. 36: 3947-55. PMID 8254623 DOI: 10.1021/Jm00076A024 |
0.311 |
|
| 1993 |
Shi D, Nikodijević O, Jacobson KA, Daly JW. Chronic caffeine alters the density of adenosine, adrenergic, cholinergic, GABA, and serotonin receptors and calcium channels in mouse brain. Cellular and Molecular Neurobiology. 13: 247-61. PMID 8242688 DOI: 10.1007/Bf00733753 |
0.439 |
|
| 1993 |
Müller CE, Shi D, Manning M, Daly JW. Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors. Journal of Medicinal Chemistry. 36: 3341-9. PMID 8230124 DOI: 10.1021/Jm00074A015 |
0.356 |
|
| 1993 |
Nikodijević O, Jacobson KA, Daly JW. Locomotor activity in mice during chronic treatment with caffeine and withdrawal. Pharmacology, Biochemistry, and Behavior. 44: 199-216. PMID 7679219 DOI: 10.1016/0091-3057(93)90299-9 |
0.426 |
|
| 1993 |
Nikodijevi? O, Jacobson KA, Daly JW. Acute treatment of mice with high doses of caffeine: An animal model for choreiform movement Drug Development Research. 30: 121-128. DOI: 10.1002/Ddr.430300304 |
0.424 |
|
| 1993 |
Nikodijevic O, Jacobson KA, Daly JW. Effects of combinations of methylxanthines and adenosine analogs on locomotor activity in control and chronic caffeine-treated mice Drug Development Research. 30: 104-110. DOI: 10.1002/Ddr.430300209 |
0.444 |
|
| 1992 |
Daly JW, Padgett WL. Agonist activity of 2- and 5'-substituted adenosine analogs and their N6-cycloalkyl derivatives at A1- and A2-adenosine receptors coupled to adenylate cyclase. Biochemical Pharmacology. 43: 1089-93. PMID 1554381 DOI: 10.1016/0006-2952(92)90616-Q |
0.358 |
|
| 1992 |
Jacobson KA, Nikodijevic O, Ji XD, Berkich DA, Eveleth D, Dean RL, Hiramatsu KI, Kassell NF, Van Galen PJM, Lee KS, Bartus RT, Daly JW, LaNoue KF, Maillard M. Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: Water-soluble and peripherally selective adenosine agonists Journal of Medicinal Chemistry. 35: 4143-4149. PMID 1433217 DOI: 10.1021/JM00100A020 |
0.403 |
|
| 1992 |
Hide I, Padgett WL, Jacobson KA, Daly JW. A2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: characterization with radioligand binding and by activation of adenylate cyclase. Molecular Pharmacology. 41: 352-9. PMID 1311411 |
0.386 |
|
| 1991 |
Karlsten R, Post C, Hide I, Daly JW. The antinociceptive effect of intrathecally administered adenosine analogs in mice correlates with the affinity for the A1-adenosine receptor. Neuroscience Letters. 121: 267-70. PMID 2020383 DOI: 10.1016/0304-3940(91)90701-T |
0.328 |
|
| 1991 |
Daly JW, Nishizawa Y, Edwards MW, Waters JA, Aronstam RS. Nicotinic receptor-elicited sodium flux in rat pheochromocytoma PC12 cells: effects of agonists, antagonists, and noncompetitive blockers. Neurochemical Research. 16: 489-500. PMID 1922660 DOI: 10.1007/Bf00965571 |
0.305 |
|
| 1991 |
Ueeda M, Thompson RD, Padgett WL, Secunda S, Daly JW, Olsson RA. Cardiovascular actions of adenosines, but not adenosine receptors, differ in rat and guinea pig. Life Sciences. 49: 1351-8. PMID 1921650 DOI: 10.1016/0024-3205(91)90199-L |
0.345 |
|
| 1991 |
Nikodijević O, Sarges R, Daly JW, Jacobson KA. Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism. The Journal of Pharmacology and Experimental Therapeutics. 259: 286-94. PMID 1920121 |
0.375 |
|
| 1991 |
Thompson RD, Secunda S, Daly JW, Olsson RA. N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor. Journal of Medicinal Chemistry. 34: 2877-82. PMID 1895305 DOI: 10.1021/Jm00113A029 |
0.342 |
|
| 1991 |
Daly JW, Nishizawa Y, Padgett WL, Tokuyama T, Smith AL, Holmes AB, Kibayashi C, Aronstam RS. 5,8-disubstituted indolizidines: a new class of noncompetitive blockers for nicotinic receptor-channels. Neurochemical Research. 16: 1213-8. PMID 1815137 DOI: 10.1007/Bf00966698 |
0.35 |
|
| 1991 |
Daly JW, Nishizawa Y, Padgett WL, Tokuyama T, McCloskey PJ, Waykole L, Schultz AG, Aronstam RS. Decahydroquinoline alkaloids: noncompetitive blockers for nicotinic acetylcholine receptor-channels in pheochromocytoma cells and Torpedo electroplax. Neurochemical Research. 16: 1207-12. PMID 1815136 DOI: 10.1007/Bf00966697 |
0.319 |
|
| 1991 |
Thompson RD, Secunda S, Daly JW, Olsson RA. Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors. Journal of Medicinal Chemistry. 34: 3388-90. PMID 1766003 DOI: 10.1021/Jm00116A007 |
0.342 |
|
| 1991 |
Daly JW, Hide I, Müller CE, Shamim M. Caffeine analogs: structure-activity relationships at adenosine receptors. Pharmacology. 42: 309-21. PMID 1658821 DOI: 10.1159/000138813 |
0.341 |
|
| 1991 |
Galbraith RA, Jellinck PH, Riesselmann A, Baron A, Fregly MJ, Cade R, Shebuski RJ, Krieglstein J, Holahan MA, Mellott MJ, Garsky VM, Wisser H, Nuglisch J, Izushi K, Tasaka K, ... Daly JW, et al. Subject Index, Vol. 42, 1991 Pharmacology. 42: 363-366. DOI: 10.1159/000138820 |
0.391 |
|
| 1991 |
Galbraith RA, Jellinck PH, Riesselmann A, Baron A, Fregly MJ, Cade R, Shebuski RJ, Krieglstein J, Holahan MA, Mellott MJ, Garsky VM, Wisser H, Nuglisch J, Izushi K, Tasaka K, ... Daly JW, et al. Contents, Vol. 42, 1991 Pharmacology. 42. DOI: 10.1159/000138811 |
0.395 |
|
| 1991 |
Jacobson KA, Nikodijevic O, de la Cruz D, Daly JW. APEC, An A2-Selective Adenosine Agonist, is a More Potent Locomotor Depressant Than N6-Cyclohexyladenosine Nucleosides and Nucleotides. 10: 1211-1212. DOI: 10.1080/07328319108047279 |
0.457 |
|
| 1991 |
Jacobson KA, Daly JW. Purine Functionalized Congeners as Molecular Probes for Adenosine Receptors Nucleosides and Nucleotides. 10: 1029-1038. DOI: 10.1080/07328319108047240 |
0.471 |
|
| 1990 |
Brackett LE, Shamim MT, Daly JW. Activities of caffeine, theophylline, and enprofylline analogs as tracheal relaxants. Biochemical Pharmacology. 39: 1897-904. PMID 2353933 DOI: 10.1016/0006-2952(90)90607-M |
0.343 |
|
| 1990 |
Nikodijević O, Daly JW, Jacobson KA. Characterization of the locomotor depression produced by an A2-selective adenosine agonist. Febs Letters. 261: 67-70. PMID 2307237 DOI: 10.1016/0014-5793(90)80638-Y |
0.465 |
|
| 1990 |
Daly JW, Hide I, Bridson PK. Imidazodiazepinediones: a new class of adenosine receptor antagonists. Journal of Medicinal Chemistry. 33: 2818-21. PMID 2213834 DOI: 10.1021/Jm00172A022 |
0.364 |
|
| 1989 |
Morgan PF, Deckert J, Jacobson KA, Marangos PJ, Daly JW. Potent convulsant actions of the adenosine receptor antagonist, xanthine amine congener (XAC). Life Sciences. 45: 719-28. PMID 2779359 DOI: 10.1016/0024-3205(89)90091-X |
0.43 |
|
| 1989 |
Jacobson KA, Kiriasis L, Barone S, Bradbury BJ, Kammula U, Campagne JM, Secunda S, Daly JW, Neumeyer JL, Pfleiderer W. Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. Journal of Medicinal Chemistry. 32: 1873-9. PMID 2754711 DOI: 10.1021/Jm00128A031 |
0.489 |
|
| 1989 |
Shamim MT, Ukena D, Padgett WL, Daly JW. Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions. Journal of Medicinal Chemistry. 32: 1231-7. PMID 2724296 DOI: 10.1021/Jm00126A014 |
0.344 |
|
| 1988 |
Deckert J, Morgan PF, Bisserbe JC, Jacobson KA, Kirk KL, Daly JW, Marangos PJ. Autoradiographic localization of mouse brain adenosine receptors with an antagonist ([3H]xanthine amine congener) ligand probe. Neuroscience Letters. 86: 121-6. PMID 3368115 DOI: 10.1016/0304-3940(88)90557-5 |
0.472 |
|
| 1988 |
Shamim MT, Ukena D, Padgett WL, Hong O, Daly JW. 8-Aryl-and 8-cycloalkyl-1,3-dipropylxanthines: further potent and selective antagonists for A1-adenosine receptors. Journal of Medicinal Chemistry. 31: 613-7. PMID 3346878 DOI: 10.1021/Jm00398A020 |
0.345 |
|
| 1988 |
Seale TW, Abla KA, Shamim MT, Carney JM, Daly JW. 3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs. Life Sciences. 43: 1671-84. PMID 3193854 DOI: 10.1016/0024-3205(88)90478-X |
0.327 |
|
| 1988 |
Daly JW, Padgett WL, Eger K. 7-Deaza-9-phenyladenines. A new class of adenosine receptor antagonists. Biochemical Pharmacology. 37: 3749-53. PMID 3178888 DOI: 10.1016/0006-2952(88)90410-8 |
0.343 |
|
| 1988 |
Jacobson KA, de la Cruz R, Schulick R, Kiriasis L, Padgett W, Pfleiderer W, Kirk KL, Neumeyer JL, Daly JW. 8-Substituted xanthines as antagonists at A1- and A2-adenosine receptors. Biochemical Pharmacology. 37: 3653-61. PMID 3178879 DOI: 10.1016/0006-2952(88)90398-X |
0.501 |
|
| 1988 |
Peet NP, Dickerson GA, Abdallah AH, Daly JW, Ukena D. Benzo[1,2-c:5,4-c']dipyrazoles: non-xanthine adenosine antagonists. Journal of Medicinal Chemistry. 31: 2034-9. PMID 3172141 DOI: 10.1021/Jm00118A032 |
0.336 |
|
| 1988 |
Daly JW, Hong O, Padgett WL, Shamim MT, Jacobson KA, Ukena D. Non-xanthine heterocycles: activity as antagonists of A1- and A2-adenosine receptors. Biochemical Pharmacology. 37: 655-64. PMID 2829919 DOI: 10.1016/0006-2952(88)90139-6 |
0.484 |
|
| 1988 |
Choi OH, Shamim MT, Padgett WL, Daly JW. Caffeine and theophylline analogues: correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors. Life Sciences. 43: 387-98. PMID 2456442 DOI: 10.1016/0024-3205(88)90517-6 |
0.326 |
|
| 1988 |
Gusovsky F, Daly JW. Formation of inositol phosphates in synaptoneurosomes of guinea pig brain: stimulatory effects of receptor agonists, sodium channel agents and sodium and calcium ionophores. Neuropharmacology. 27: 95-105. PMID 2451187 DOI: 10.1016/0028-3908(88)90206-7 |
0.327 |
|
| 1987 |
Jacobson KA, Ukena D, Padgett W, Daly JW, Kirk KL. Xanthine functionalized congeners as potent ligands at A2-adenosine receptors. Journal of Medicinal Chemistry. 30: 211-4. PMID 3806597 DOI: 10.1021/Jm00384A037 |
0.48 |
|
| 1987 |
Jacobson KA, Zimmet J, Schulick R, Barone S, Daly JW, Kirk KL. Adenosine analogs with covalently attached lipids have enhanced potency at A1-adenosine receptors. Febs Letters. 225: 97-102. PMID 3691809 DOI: 10.1016/0014-5793(87)81138-9 |
0.486 |
|
| 1987 |
Evoniuk G, Jacobson KA, Shamim MT, Daly JW, Wurtman RJ. A1- and A2-selective adenosine antagonists: in vivo characterization of cardiovascular effects. The Journal of Pharmacology and Experimental Therapeutics. 242: 882-7. PMID 3656117 |
0.395 |
|
| 1987 |
Ukena D, Olsson RA, Daly JW. Definition of subclasses of adenosine receptors associated with adenylate cyclase: interaction of adenosine analogs with inhibitory A1 receptors and stimulatory A2 receptors. Canadian Journal of Physiology and Pharmacology. 65: 365-76. PMID 3580959 DOI: 10.1139/Y87-063 |
0.335 |
|
| 1987 |
Hollingsworth EB, Daly JW. Inhibition of receptor-mediated stimulation of cyclic AMP accumulation in neuroblastoma-hybrid NCB-20 cells by a phorbol ester. Biochimica Et Biophysica Acta. 930: 272-8. PMID 3040124 DOI: 10.1016/0167-4889(87)90040-1 |
0.331 |
|
| 1987 |
Gusovsky F, McNeal ET, Olubajo O, Kirk KL, Creveling CR, Daly JW. Effects of ring fluorination on the adrenergic properties of phenylephrine. European Journal of Pharmacology. 136: 317-24. PMID 3038567 DOI: 10.1016/0014-2999(87)90304-9 |
0.307 |
|
| 1987 |
Jacobson KA, Ukena D, Padgett W, Kirk KL, Daly JW. Molecular probes for extracellular adenosine receptors. Biochemical Pharmacology. 36: 1697-707. PMID 3036153 DOI: 10.1016/0006-2952(87)90056-6 |
0.483 |
|
| 1987 |
Bolger GT, Marcus KA, Daly JW, Skolnick P. Local anesthetics differentiate dihydropyridine calcium antagonist binding sites in rat brain and cardiac membranes. The Journal of Pharmacology and Experimental Therapeutics. 240: 922-30. PMID 3031279 |
0.413 |
|
| 1987 |
Jacobson KA, Lipkowski AW, Moody TW, Padgett W, Pijl E, Kirk KL, Daly JW. Binary drugs: conjugates of purines and a peptide that bind to both adenosine and substance P receptors. Journal of Medicinal Chemistry. 30: 1529-32. PMID 2441057 DOI: 10.1021/Jm00391A046 |
0.465 |
|
| 1987 |
Fredholm BB, Jacobson KA, Jonzon B, Kirk KL, Li YO, Daly JW. Evidence that a novel 8-phenyl-substituted xanthine derivative is a cardioselective adenosine receptor antagonist in vivo. Journal of Cardiovascular Pharmacology. 9: 396-400. PMID 2438501 DOI: 10.1097/00005344-198704000-00003 |
0.394 |
|
| 1987 |
JACOBSON KA, UKENA D, PADGETT W, DALY JW, KIRK KL. ChemInform Abstract: Xanthine Functionalized Congeners as Potent Ligands at A2-Adenosine Receptors. Cheminform. 18. DOI: 10.1002/CHIN.198724231 |
0.374 |
|
| 1986 |
Daly JW, Padgett WL, Shamim MT. Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors. Journal of Medicinal Chemistry. 29: 1305-8. PMID 3806581 DOI: 10.1002/Chin.198648334 |
0.332 |
|
| 1986 |
Ukena D, Jacobson KA, Padgett WL, Ayala C, Shamim MT, Kirk KL, Olsson RO, Daly JW. Species differences in structure-activity relationships of adenosine agonists and xanthine antagonists at brain A1 adenosine receptors. Febs Letters. 209: 122-8. PMID 3803571 DOI: 10.1016/0014-5793(86)81096-1 |
0.482 |
|
| 1986 |
Kirk KL, Olubajo O, Buchhold K, Lewandowski GA, Gusovsky F, McCulloh D, Daly JW, Creveling CR. Synthesis and adrenergic activity of ring-fluorinated phenylephrines. Journal of Medicinal Chemistry. 29: 1982-8. PMID 3020250 DOI: 10.1021/Jm00160A030 |
0.311 |
|
| 1986 |
Olsson RA, Kusachi S, Thompson RD, Ukena D, Padgett W, Daly JW. N6-substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors. Journal of Medicinal Chemistry. 29: 1683-9. PMID 3018244 DOI: 10.1021/Jm00159A020 |
0.339 |
|
| 1986 |
Daly JW, Padgett W, Thompson RD, Kusachi S, Bugni WJ, Olsson RA. Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow. Biochemical Pharmacology. 35: 2467-81. PMID 3017353 DOI: 10.1016/0006-2952(86)90042-0 |
0.339 |
|
| 1986 |
Ukena D, Shamim MT, Padgett W, Daly JW. Analogs of caffeine: antagonists with selectivity for A2 adenosine receptors. Life Sciences. 39: 743-50. PMID 3016449 DOI: 10.1016/0024-3205(86)90023-8 |
0.331 |
|
| 1986 |
Waters JA, Hollingsworth EB, Daly JW, Lewandowski G, Creveling CR. Anticonvulsant activity of piperidinol and (dialkylamino)alkanol esters. Journal of Medicinal Chemistry. 29: 1512-6. PMID 3016269 DOI: 10.1021/Jm00158A032 |
0.301 |
|
| 1986 |
Paul SM, Schwartz RD, Creveling CR, Hollingsworth EB, Daly JW, Skolnick P. GABA receptor-mediated chloride transport in a "cell-free" membrane preparation from brain. Science (New York, N.Y.). 233: 228-9. PMID 3014649 DOI: 10.1126/Science.3014649 |
0.461 |
|
| 1986 |
Jacobson KA, Yamada N, Kirk KL, Daly JW, Olsson RA. N6-functionalized congeners of adenosine with high potency at A2-adenosine receptors: potential ligands for affinity chromatography. Biochemical and Biophysical Research Communications. 136: 1097-102. PMID 3013167 DOI: 10.1016/0006-291X(86)90446-8 |
0.467 |
|
| 1986 |
Jacobson KA, Ukena D, Kirk KL, Daly JW. [3H]xanthine amine congener of 1,3-dipropyl-8-phenylxanthine: an antagonist radioligand for adenosine receptors. Proceedings of the National Academy of Sciences of the United States of America. 83: 4089-93. PMID 3012550 DOI: 10.1073/Pnas.83.11.4089 |
0.403 |
|
| 1986 |
Ukena D, Jacobson KA, Kirk KL, Daly JW. A [3H]amine congener of 1,3-dipropyl-8-phenylxanthine. A new radioligand for A2 adenosine receptors of human platelets. Febs Letters. 199: 269-74. PMID 3009222 DOI: 10.1016/0014-5793(86)80493-8 |
0.49 |
|
| 1986 |
Hollingsworth EB, De la Cruz RA, Daly JW. Accumulations of inositol phosphates and cyclic AMP in brain slices: synergistic interactions of histamine and 2-chloroadenosine. European Journal of Pharmacology. 122: 45-50. PMID 3007178 DOI: 10.1016/0014-2999(86)90156-1 |
0.356 |
|
| 1986 |
Ukena D, Daly JW, Kirk KL, Jacobson KA. Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells. Life Sciences. 38: 797-807. PMID 3005794 DOI: 10.1016/0024-3205(86)90596-5 |
0.478 |
|
| 1986 |
Hollingsworth EB, Sears EB, de la Cruz RA, Gusovsky F, Daly JW. Accumulations of cyclic AMP and inositol phosphates in guinea pig cerebral cortical synaptoneurosomes: enhancement by agents acting at sodium channels. Biochimica Et Biophysica Acta. 883: 15-25. PMID 2425852 DOI: 10.1016/0304-4165(86)90129-7 |
0.312 |
|
| 1986 |
Gusovsky F, Hollingsworth EB, Daly JW. Regulation of phosphatidylinositol turnover in brain synaptoneurosomes: stimulatory effects of agents that enhance influx of sodium ions. Proceedings of the National Academy of Sciences of the United States of America. 83: 3003-7. PMID 2422664 DOI: 10.1073/Pnas.83.9.3003 |
0.306 |
|
| 1986 |
Gusovsky F, Daly JW. Scorpion venom (Leiurus quinquestriatus) elicits accumulations of inositol phosphates and cyclic AMP in guinea pig cortical synaptoneurosomes. Febs Letters. 199: 107-12. PMID 2420645 DOI: 10.1016/0014-5793(86)81234-0 |
0.3 |
|
| 1986 |
Jacobson KA, Ukena D, Daly JW, Kirk KL. Synthesis of tritiated functionalized congeners of 1.3-dipropylxanthine having high affinity at adenosine receptors Journal of Labelled Compounds and Radiopharmaceuticals. 23: 519-526. DOI: 10.1002/Jlcr.2580230509 |
0.481 |
|
| 1985 |
Jakobson KA, Kirk KL, Daly JW, Jonzon B, Li YO, Fredholm BB. A novel 8-phenyl-substituted xanthine derivative is a selective antagonist at adenosine A1-receptors in vivo. Acta Physiologica Scandinavica. 125: 341-2. PMID 3000136 DOI: 10.1111/J.1748-1716.1985.Tb07725.X |
0.339 |
|
| 1985 |
Hollingsworth EB, Daly JW. Accumulation of inositol phosphates and cyclic AMP in guinea-pig cerebral cortical preparations. Effects of norepinephrine, histamine, carbamylcholine and 2-chloroadenosine. Biochimica Et Biophysica Acta. 847: 207-16. PMID 2998481 DOI: 10.1016/0167-4889(85)90022-9 |
0.321 |
|
| 1985 |
Jacobson KA, Kirk KL, Padgett WL, Daly JW. Functionalized congeners of adenosine: preparation of analogues with high affinity for A1-adenosine receptors. Journal of Medicinal Chemistry. 28: 1341-6. PMID 2993623 DOI: 10.1021/Jm00147A039 |
0.5 |
|
| 1985 |
Jacobson KA, Kirk KL, Padgett WL, Daly JW. Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors. Journal of Medicinal Chemistry. 28: 1334-40. PMID 2993622 DOI: 10.1021/Jm00147A038 |
0.5 |
|
| 1985 |
Jacobson KA, Kirk KL, Padgett W, Daly JW. Probing the adenosine receptor with adenosine and xanthine biotin conjugates. Febs Letters. 184: 30-5. PMID 2985445 DOI: 10.1016/0014-5793(85)80646-3 |
0.483 |
|
| 1985 |
Daly JW, Padgett W, Shamim MT, Butts-Lamb P, Waters J. 1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors. Journal of Medicinal Chemistry. 28: 487-92. PMID 2984420 DOI: 10.1002/Chin.198531247 |
0.328 |
|
| 1985 |
Aronstam RS, King CT, Albuquerque EX, Daly JW, Feigl DM. Binding of [3H]perhydrohistrionicotoxin and [3H]phencyclidine to the nicotinic receptor-ion channel complex of Torpedo electroplax. Inhibition by histrionicotoxins and derivatives. Biochemical Pharmacology. 34: 3037-47. PMID 2412560 DOI: 10.1016/0006-2952(85)90145-5 |
0.303 |
|
| 1985 |
JACOBSON KA, KIRK KL, PADGETT WL, DALY JW. ChemInform Abstract: FUNCTIONALIZED CONGENERS OF ADENOSINE: PREPARATION OF ANALOGS WITH HIGH AFFINITY FOR A1-ADENOSINE RECEPTORS Chemischer Informationsdienst. 16. DOI: 10.1002/CHIN.198552312 |
0.394 |
|
| 1985 |
JACOBSON KA, KIRK KL, PADGETT WL, DALY JW. ChemInform Abstract: FUNCTIONALIZED CONGENERS OF 1,3-DIALKYLXANTHINES: PREPARATION OF ANALOGS WITH HIGH AFFINITY FOR ADENOSINE RECEPTORS Chemischer Informationsdienst. 16. DOI: 10.1002/CHIN.198552234 |
0.382 |
|
| 1984 |
Glennon RA, Tejani-Butt SM, Padgett W, Daly JW. Mesoionic xanthine analogues: antagonists of adenosine receptors. Journal of Medicinal Chemistry. 27: 1364-7. PMID 6090665 DOI: 10.1002/Chin.198509254 |
0.354 |
|
| 1984 |
Weir RL, Padgett W, Daly JW, Anderson SM. Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system. Epilepsia. 25: 492-8. PMID 6086302 DOI: 10.1111/J.1528-1157.1984.Tb03449.X |
0.361 |
|
| 1983 |
Daly JW, Butts-Lamb P, Padgett W. Subclasses of adenosine receptors in the central nervous system: interaction with caffeine and related methylxanthines. Cellular and Molecular Neurobiology. 3: 69-80. PMID 6309393 DOI: 10.1007/Bf00734999 |
0.344 |
|
| 1983 |
Bruns RF, Daly JW, Snyder SH. Adenosine receptor binding: structure-activity analysis generates extremely potent xanthine antagonists. Proceedings of the National Academy of Sciences of the United States of America. 80: 2077-80. PMID 6300892 DOI: 10.1073/Pnas.80.7.2077 |
0.375 |
|
| 1983 |
Bruns RF, Katims JJ, Annau Z, Snyder SH, Daly JW. Adenosine receptor interactions and anxiolytics. Neuropharmacology. 22: 1523-9. PMID 6199685 DOI: 10.1016/0028-3908(83)90121-1 |
0.347 |
|
| 1982 |
Ebstein RP, Daly JW. Release of norepinephrine and dopamine from brain vesicular preparations: effects of adenosine analogues. Cellular and Molecular Neurobiology. 2: 193-204. PMID 7159901 DOI: 10.1007/Bf00711147 |
0.334 |
|
| 1982 |
Nimit Y, Law J, Daly JW. Binding of 2',5'-dideoxyadenosine to brain membranes. Comparison to P-site inhibition of adenylate cyclase. Biochemical Pharmacology. 31: 3279-87. PMID 6983353 DOI: 10.1016/0006-2952(82)90562-7 |
0.32 |
|
| 1982 |
Ebstein RP, Seamon K, Creveling CR, Daly JW. Release of norepinephrine from brain vesicular preparations: effects of an adenylate cyclase activator, forskolin, and a phosphodiesterase inhibitor. Cellular and Molecular Neurobiology. 2: 179-92. PMID 6891616 DOI: 10.1007/Bf00711146 |
0.308 |
|
| 1982 |
Daly JW, Padgett W, Seamon KB. Activation of cyclic AMP-generating systems in brain membranes and slices by the diterpene forskolin: augmentation of receptor-mediated responses. Journal of Neurochemistry. 38: 532-44. PMID 6125572 DOI: 10.1111/J.1471-4159.1982.Tb08660.X |
0.342 |
|
| 1981 |
Seamon KB, Padgett W, Daly JW. Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 3363-7. PMID 6267587 DOI: 10.1073/Pnas.78.6.3363 |
0.346 |
|
| 1981 |
Snyder SH, Katims JJ, Annau Z, Bruns RF, Daly JW. Adenosine receptors and behavioral actions of methylxanthines [caffeine/theophylline/N 6-cyclohexyladenosine/N 6-(phenylisopropyl)adenosine] Proceedings of the National Academy of Sciences of the United States of America. 78: 3260-3264. PMID 6265942 DOI: 10.1073/Pnas.78.5.3260 |
0.306 |
|
| 1981 |
Nimit Y, Skolnick P, Daly JW. Adenosine and cyclic AMP in rat cerebral cortical slices: effects of adenosine uptake inhibitors and adenosine deaminase inhibitors. Journal of Neurochemistry. 36: 908-12. PMID 6259294 DOI: 10.1111/J.1471-4159.1981.Tb01680.X |
0.512 |
|
| 1981 |
Daly JW, Bruns RF, Snyder SH. Adenosine receptors in the central nervous system: relationship to the central actions of methylxanthines. Life Sciences. 28: 2083-97. PMID 6114369 DOI: 10.1016/0024-3205(81)90614-7 |
0.34 |
|
| 1980 |
McNeal ET, Creveling CR, Daly JW. Cyclic AMP-generating systems in cell-free preparations from guinea pig cerebral cortex: Loss of adenosine and amine responsiveness due to low levels of endogenous adenosine Journal of Neurochemistry. 35: 338-342. PMID 6256482 DOI: 10.1111/J.1471-4159.1980.Tb06269.X |
0.316 |
|
| 1980 |
Daly JW, McNeal E, Partington C, Neuwirth M, Creveling CR. Accumulations of cyclic AMP in adenine-labeled cell-free preparations from guinea pig cerebral cortex: role of alpha-adrenergic and H1-histaminergic receptors. Journal of Neurochemistry. 35: 326-37. PMID 6256481 DOI: 10.1111/J.1471-4159.1980.Tb06268.X |
0.341 |
|
| 1980 |
Partington CR, Edwards MW, Daly JW. Calcium-dependent desensitization of adenylate cyclase in rat cerebral cortical slices Journal of Neurochemistry. 34: 76-82. PMID 6256474 DOI: 10.1111/J.1471-4159.1980.Tb04623.X |
0.305 |
|
| 1980 |
Nimit Y, Cantacuzene D, Kirk KL, Creveling CR, Daly JW. The binding of fluorocatecholamines to adrenergic and dopaminergic receptors in rat brain membranes Life Sciences. 27: 1577-1585. PMID 6255279 DOI: 10.1016/0024-3205(80)90567-6 |
0.31 |
|
| 1980 |
Partington CR, Edwards MW, Daly JW. Regulation of cyclic AMP formation in brain tissue by α-adrenergic receptors: Requisite intermediacy of prostaglandins of the E series Proceedings of the National Academy of Sciences of the United States of America. 77: 3024-3028. PMID 6248884 DOI: 10.1073/Pnas.77.5.3024 |
0.325 |
|
| 1980 |
Brossi A, Rice KC, Mak CP, Reden J, Jacobson AE, Nimitkitpaisan Y, Skolnick P, Daly J. Mammalian alkaloids. 8. Synthesis and biological effects of tetrahydropapaveroline related 1-benzyltetrahydroisoquinolines. Journal of Medicinal Chemistry. 23: 648-52. PMID 6248642 DOI: 10.1002/Chin.198043308 |
0.46 |
|
| 1979 |
Partington CR, Daly JW. Effect of proteases and protease inhibitors on adenylate cyclase activity in rat cerebral cortical membranes Archives of Biochemistry and Biophysics. 198: 255-262. PMID 507844 DOI: 10.1016/0003-9861(79)90417-X |
0.305 |
|
| 1979 |
Kirk KL, Cantacuzene D, Nimitkitpaisan Y, McCulloh D, Padgett WL, Daly JW, Creveling CR. Synthesis and biological properties of 2-, 5-, and 6-fluoronorepinephrines. Journal of Medicinal Chemistry. 22: 1493-7. PMID 231654 DOI: 10.1002/Chin.198015179 |
0.305 |
|
| 1979 |
Smellie FW, Daly JW, Dunwiddie TV, Hoffer BJ. The dextro and levorotatory isomers of N-phenylisopropyladenosine: stereospecific effects on cyclic AMP-formation and evoked synaptic responses in brain slices. Life Sciences. 25: 1739-48. PMID 231163 DOI: 10.1016/0024-3205(79)90477-6 |
0.317 |
|
| 1979 |
Smellie FW, Daly JW, Wells JN. 1-Isoamyl-3-isobutylxanthine: A remarkably potent agent for the potentiation of norepinephrine, histamine, and adenosine-elicited accumulations of cyclic AMP in brain slices Life Sciences. 25: 1917-1924. PMID 93674 DOI: 10.1016/0024-3205(79)90613-1 |
0.367 |
|
| 1978 |
Eldefrawi ME, Eldefrawi AT, Mansour NA, Daly JW, Witkop B, Albuquerque EX. Acetylcholine receptor and ionic channel of Torpedo electroplax: binding of perhydrohistrionicotoxin to membrane and solubilized preparations. Biochemistry. 17: 5474-84. PMID 728410 DOI: 10.1021/Bi00618A023 |
0.5 |
|
| 1978 |
Skolnick P, Nimitkitpaisan Y, Stalvey L, Daly JW. Inhibition of brain adenosine deaminase by 2'-deoxycoformycin and erythro-9-(2-hydroxy-3-nonyl) adenine. Journal of Neurochemistry. 30: 1479-82. PMID 670988 DOI: 10.1111/J.1471-4159.1978.Tb10496.X |
0.473 |
|
| 1978 |
Garrison DL, Albuquerque EX, Warnick JE, Daly JW, Witkop B. Antagonism of carbamylcholine-induced depolarization by batrachotoxin and veratridine. Molecular Pharmacology. 14: 111-21. PMID 304959 |
0.367 |
|
| 1978 |
Schwabe U, Ohga Y, Daly JW. The role of calcium in the regulation of cyclic nucleotide levels in brain slices of rat and guinea pig. Naunyn-Schmiedeberg's Archives of Pharmacology. 302: 141-51. PMID 206846 DOI: 10.1007/Bf00517981 |
0.316 |
|
| 1978 |
Skolnick P, Daly JW, Segal DS. Neurochemical and behavioral effects of clonidine and related imidazolines: interaction with alpha-adrenoceptors. European Journal of Pharmacology. 47: 451-5. PMID 204500 DOI: 10.1016/0014-2999(78)90126-7 |
0.476 |
|
| 1978 |
Davis JN, Arnett CD, Hoyler E, Stalvey LP, Daly JW, Skolnick P. Brain alpha-adrenergic receptors: comparison of [3H]WB 4101 binding with norepinephrine-stimulated cyclic AMP accumulation in rat cerebral cortex. Brain Research. 159: 125-35. PMID 31963 DOI: 10.1016/0006-8993(78)90114-2 |
0.505 |
|
| 1978 |
Skolnick P, Stalvey LP, Daly JW, Hoyler E, Davis JN. Binding of alpha-and beta-adrenergic ligands to cerebral cortical membranes: effect of 6-hydroxydopamine treatment and relationship to the responsiveness of cyclic amp-generating systems in two rat strains. European Journal of Pharmacology. 47: 201-10. PMID 23299 DOI: 10.1016/0014-2999(78)90391-6 |
0.486 |
|
| 1977 |
Daly JW, Witkop B, Tokuyama T, Nishikawa T, Karle IL. Gephyrotoxins, histrionicotoxins and pumiliotoxins from the neotropical frog Dendrobates histrionicus. Helvetica Chimica Acta. 60: 1128-40. PMID 863724 DOI: 10.1002/Chin.197731320 |
0.432 |
|
| 1977 |
Eldefrawi AT, Eldefrawi ME, Albuquerque EX, Oliveira AC, Mansour N, Adler M, Daly JW, Brown GB, Burgermeister W, Witkop B. Perhydrohistrionicotoxin: a potential ligand for the ion conductance modulator of the acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 74: 2172-6. PMID 301278 DOI: 10.1073/Pnas.74.5.2172 |
0.489 |
|
| 1977 |
Ohga Y, Daly JW. The accumulation of cyclic AMP and cyclic GMP in guinea pig brain slices. Effect of calcium ions, norepinephrine and adenosine. Biochimica Et Biophysica Acta. 498: 46-60. PMID 195635 DOI: 10.1016/0304-4165(77)90086-1 |
0.313 |
|
| 1977 |
Mah HD, Daly JW. Adenosine-dependent formation of cyclic AMP in brain slices. Pharmacological Research Communications. 8: 65-79. PMID 194256 DOI: 10.1016/0031-6989(76)90030-8 |
0.324 |
|
| 1977 |
Skolnick P, Daly JW. Strain differences in responsiveness of norepinephrine-sensitive adenosine 3',5'-monophosphate-generating systems in rat brain slices after intraventricular administration of 6-hydroxydopamine. European Journal of Pharmacology. 41: 145-52. PMID 188662 DOI: 10.1016/0014-2999(77)90203-5 |
0.464 |
|
| 1977 |
Skolnick P, Stalvey LP, Daly JW. Blockade of central beta-adrenergic receptors by tazolol (1-isopropylamino-3-(2-thiazoloxy)-2-propanol). Life Sciences. 21: 1655-63. PMID 23478 DOI: 10.1016/0024-3205(77)90245-4 |
0.49 |
|
| 1976 |
Boyd DR, Campbell RM, Craig HC, Watson CG, Daly JW, Jerina DM. Mechanism of aromatic hydroxylation in fungi. Evidence for the formation of arene oxides. Journal of the Chemical Society. Perkin Transactions 1. 2438-43. PMID 1033945 DOI: 10.1039/P19760002438 |
0.485 |
|
| 1976 |
Skolnick P, Daly JW. Interaction of clonidine with pre- and post-synaptic adrenergic receptors of rat brain: effects on cyclic AMP-generating systems. European Journal of Pharmacology. 39: 11-21. PMID 183964 DOI: 10.1016/0014-2999(76)90108-4 |
0.498 |
|
| 1976 |
Skolnick P, Daly JW. Antagonism of alpha- and beta-adrenergic-mediated accumulations of cyclic AMP in rat cerebral cortical slices by the beta-antagonist (-)alprenolol. Life Sciences. 19: 497-503. PMID 8683 DOI: 10.1016/0024-3205(76)90228-9 |
0.508 |
|
| 1976 |
Daly JW. The nature of receptors regulating the formation of cyclic AMP in brain tissue. Life Sciences. 18: 1349-58. PMID 7721 DOI: 10.1016/0024-3205(76)90350-7 |
0.326 |
|
| 1976 |
Skolnick P, Daly JW, Freedman R, Hoffer BJ. Interrelationship between catecholamine-stimulated formation of adenosine 3',5'-monophosphate in cerebellar slices and inhibitory effects on cerebellar Purkinje cells: antagonism by neuroleptic compounds. The Journal of Pharmacology and Experimental Therapeutics. 197: 280-92. PMID 5595 |
0.404 |
|
| 1976 |
Habermehl G, Andres H, Miyahara K, Witkop B, Daly JW. Synthese von Pumiliotoxin C Justus Liebigs Annalen Der Chemie. 1976: 1577-1583. DOI: 10.1002/Jlac.197619760906 |
0.456 |
|
| 1976 |
HABERMEHL G, ANDRES H, MIYAHARA K, WITKOP B, DALY JW. ChemInform Abstract: SYNTHESIS OF PUMILIOTOXIN C Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197651338 |
0.457 |
|
| 1975 |
Selander HG, Jerina DM, Daly JW. Metabolism of acetanilide with hepatic microsomes and reconstituted cytochrome monoxygenase systems. Archives of Biochemistry and Biophysics. 164: 241-6. PMID 4429351 DOI: 10.1016/0003-9861(74)90028-9 |
0.487 |
|
| 1975 |
Huang M, Daly JW. Interrelationships among the levels of ATP, adenosine and cyclic AMP in incubated slices of guinea-pig cerebral cortex: effects of depolarizing agents, psychotropic drugs and metabolic inhibitors. Journal of Neurochemistry. 23: 393-404. PMID 4371573 DOI: 10.1111/J.1471-4159.1974.Tb04371.X |
0.313 |
|
| 1975 |
Lapa AJ, Albuquerque EX, Sarvey JM, Daly J, Witkop B. Effects of histrionicotoxin on the chemosensitive and electrical properties of skeletal muscle. Experimental Neurology. 47: 558-80. PMID 1132464 DOI: 10.1016/0014-4886(75)90088-6 |
0.472 |
|
| 1975 |
Tomaszewski JE, Jerina DM, Daly JW. Deuterium isotope effects during formation of phenols by hepatic monoxygenases. Evidence for an alternative to arene oxide pathway. Biochemistry. 14: 2024-31. PMID 1125208 DOI: 10.1021/Bi00680A033 |
0.424 |
|
| 1975 |
Selander HG, Jerina DM, Daly JW. Metobolism of chlorobenzene with hepatic microsomes and solubilized cytochrome P-450 systems. Archives of Biochemistry and Biophysics. 168: 309-21. PMID 806264 DOI: 10.1016/0003-9861(75)90255-6 |
0.495 |
|
| 1975 |
Skolnick P, Daly JW. Stimulation of adenosine 3',5'-monophosphate formation by alpha and beta adrenergic agonists in rat cerebral cortical slices: effects of clonidine. Molecular Pharmacology. 11: 545-51. PMID 241008 |
0.402 |
|
| 1975 |
Skolnick P, Daly JW. Stimulation of adenosine 3',5'-monophosphate formation in rat cerebral cortical slices by methoxamine: interaction with an alpha adrenergic receptor. The Journal of Pharmacology and Experimental Therapeutics. 193: 549-58. PMID 238025 |
0.441 |
|
| 1975 |
Weissman BA, Daly JW, Skolnick P. Diethylstilbestrol-elicited accumulation of cyclic AMP in incubated rat hypothalamus. Endocrinology. 97: 1559-66. PMID 173528 DOI: 10.1210/Endo-97-6-1559 |
0.615 |
|
| 1975 |
Dismukes K, Daly JW. Accumulation of adenosine 3',5'-monophosphate in rat brain slices: effects of prostaglandins. Life Sciences. 17: 199-209. PMID 169447 DOI: 10.1016/0024-3205(75)90504-4 |
0.344 |
|
| 1975 |
Skolnick P, Schultz J, Daly JW. Repetitive stimulation of cyclic adenosine 3',5'-monophosphate formation by adrenergic agonists in incubated slices from rat cerebral cortex. Journal of Neurochemistry. 24: 1263-5. PMID 165265 DOI: 10.1111/J.1471-4159.1975.Tb03909.X |
0.485 |
|
| 1975 |
Skolnick P, Daly JW. Functional compartments of adenine nucleotides serving as precursors of adenosine 3',5'-monophosphate in mouse cerebral cortex. Journal of Neurochemistry. 24: 451-6. PMID 163293 DOI: 10.1111/J.1471-4159.1975.Tb07661.X |
0.514 |
|
| 1975 |
Mah HD, Daly JW. Intracellular formation of analogues of cyclic AMP: Studies with brain slices labeled with radioactive derivatives of adenine and adenosine Biochimica Et Biophysica Acta. 404: 49-56. DOI: 10.1016/0304-4165(75)90146-4 |
0.338 |
|
| 1974 |
Jerina DM, Daly JW. Arene oxides: a new aspect of drug metabolism. Science (New York, N.Y.). 185: 573-82. PMID 4841570 DOI: 10.1126/Science.185.4151.573 |
0.37 |
|
| 1974 |
Dansette PM, Yagi H, Jerina DM, Daly JW, Levin W, Lu AY, Kuntzman R, Conney AH. Assay and partial purification of epoxide hydrase from rat liver microsomes. Archives of Biochemistry and Biophysics. 164: 511-7. PMID 4460878 DOI: 10.1016/0003-9861(74)90061-7 |
0.659 |
|
| 1974 |
Tokuyama T, Uenoyama K, Brown G, Daly JW, Witkop B. Allenic and acetylenic spiropiperidine alkaloids from the neotropical frog, Dendrobates histrionicus. Helvetica Chimica Acta. 57: 2597-604. PMID 4443292 DOI: 10.1002/Chin.197510439 |
0.464 |
|
| 1974 |
Skolnick P, Daly JW. The accumulation of adenosine 3',5'-monophosphate in cerebral cortical slices of the quaking mouse, a neurologic mutant. Brain Research. 73: 513-25. PMID 4366158 DOI: 10.1016/0006-8993(74)90674-X |
0.48 |
|
| 1974 |
Huang M, Daly JW. Adenosine-elicited accumulation of cyclic AMP in brain slices: potentiation by agents which inhibit uptake of adenosine. Life Sciences. 14: 489-503. PMID 4363081 DOI: 10.1016/0024-3205(74)90364-6 |
0.347 |
|
| 1974 |
Huang M, Gruenstein E, Daly JW. Depolarization-evoked accumulation of cyclic AMP in brain slices: inhibition by exogenous adenosine deaminase. Biochimica Et Biophysica Acta. 329: 147-51. PMID 4361563 DOI: 10.1016/0304-4165(73)90017-2 |
0.308 |
|
| 1974 |
Schultz J, Daly JW. Acummulation of cyclic adenosine 3', 5'-monophosphate in cerebral cortical slices from rat and mouse: stimulatory effect of alpha- and beta-adrenergic agents and adenosine. Journal of Neurochemistry. 21: 1319-26. PMID 4357503 DOI: 10.1111/J.1471-4159.1973.Tb07585.X |
0.334 |
|
| 1974 |
Skolnick P, Daly JW. Norepinephrine-sensitive adenylate cyclases in rat brain: relation to behavior and tyrosine hydroxylase. Science (New York, N.Y.). 184: 175-7. PMID 4150105 DOI: 10.1126/Science.184.4133.175 |
0.468 |
|
| 1974 |
JERINA DM, DALY JW. ChemInform Abstract: ARENE OXIDES, A NEW ASPECT OF DRUG METABOLISM Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/Chin.197452267 |
0.375 |
|
| 1973 |
Ferris JP, Fasco MJ, Stylianopoulou FL, Jerina DM, Daly JW, Jeffrey AM. Monooxygenase activity in Cunninghamella bainieri: evidence for a fungal system similar to liver microsomes. Archives of Biochemistry and Biophysics. 156: 97-103. PMID 4730481 DOI: 10.1016/0003-9861(73)90345-7 |
0.483 |
|
| 1973 |
Reed DJ, Vimmerstedt J, Jerina DM, Daly JW. Formation of phenols from aromatic subtrates by plant and animal mono-oxygenases: The effect of adjacent deuteriums on the magnitude of the NIH shift of tritium Archives of Biochemistry and Biophysics. 154: 642-647. PMID 4691507 DOI: 10.1016/0003-9861(73)90019-2 |
0.49 |
|
| 1973 |
Oesch F, Jerina DM, Daly JW, Lu AY, Kuntzman R, Conney AH. A reconstituted microsomal enzyme system that converts naphthalene to trans-1,2-dihydroxy-1,2-dihydronaphthalene via naphthalene-1,2-oxide: presence of epoxide hydrase in cytochrome P-450 and P-448 fractions. Archives of Biochemistry and Biophysics. 153: 62-7. PMID 4650623 DOI: 10.1016/0003-9861(72)90420-1 |
0.474 |
|
| 1973 |
Oesch F, Jerina DM, Daly JW, Rice JM. Induction, activation and inhibition of epoxide hydrase: an anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase Chemico-Biological Interactions. 6: 189-202. PMID 4632460 DOI: 10.1016/0009-2797(73)90071-9 |
0.5 |
|
| 1973 |
Skolnick P, Huang M, Daly J, Hoffer B. Accumulation of adenosine 3', 5'-monophosphate in incubated slices from discrete regions of squirrel monkey cerebral cortex: effect of norepinephrine, serotonin and adenosine. Journal of Neurochemistry. 21: 237-40. PMID 4352758 DOI: 10.1111/J.1471-4159.1973.Tb04243.X |
0.474 |
|
| 1973 |
Albuquerque EX, Barnard EA, Chiu TH, Lapa AJ, Dolly JO, Jansson SE, Daly J, Witkop B. Acetylcholine receptor and ion conductance modulator sites at the murine neuromuscular junction: evidence from specific toxin reactions. Proceedings of the National Academy of Sciences of the United States of America. 70: 949-53. PMID 4351811 DOI: 10.1073/Pnas.70.3.949 |
0.488 |
|
| 1973 |
Schultz J, Daly JW. Adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices: effects of alpha- and beta-adrenergic agents, histamine, serotonin and adenosine. Journal of Neurochemistry. 21: 573-9. PMID 4147500 DOI: 10.1111/J.1471-4159.1973.Tb06002.X |
0.321 |
|
| 1973 |
Jerina DM, Yagi H, Daly JW. Arene Oxides‐Oxepins Cheminform. 16: 197-282. DOI: 10.1002/9780470187203.Ch2 |
0.431 |
|
| 1972 |
Jerina DM, Kaubisch N, Daly JW. Arene oxides as intermediates in the metabolism of aromatic substrates: alkyl and oxygen migrations during isomerization of alkylated arene oxides. Proceedings of the National Academy of Sciences of the United States of America. 68: 2545-8. PMID 5289888 DOI: 10.1073/Pnas.68.10.2545 |
0.478 |
|
| 1972 |
Oesch F, Kaubisch N, Jerina DM, Daly JW. Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors. Biochemistry. 10: 4858-66. PMID 5134533 DOI: 10.1021/Bi00802A005 |
0.451 |
|
| 1972 |
Oesch F, Jerina DM, Daly JW. Substrate specificity of hepatic epoxide hydrase in microsomes and in a purified preparation: evidence for homologous enzymes. Archives of Biochemistry and Biophysics. 144: 253-61. PMID 5117530 DOI: 10.1016/0003-9861(71)90476-0 |
0.481 |
|
| 1972 |
Lutz WB, Creveling CR, Daly JW, Witkop B. Sulfur analogs of dopamine and norepinephrine. Inhibition of catechol-O-methyltransferase. Journal of Medicinal Chemistry. 15: 795-802. PMID 5044295 DOI: 10.1021/Jm00278A004 |
0.458 |
|
| 1972 |
Kaubisch N, Daly JW, Jerina DM. Arene oxides as intermediates in the oxidative metabolism of aromatic compounds. Isomerization of methyl-substituted arene oxides. Biochemistry. 11: 3080-8. PMID 5041913 DOI: 10.1021/Bi00766A022 |
0.476 |
|
| 1972 |
Boyd DR, Daly JW, Jerina DM. Rearrangement of (1- 2 H)- and (2- 2 H)naphthalene 1,2-oxides to 1-naphthol. Mechanism of the NIH shift. Biochemistry. 11: 1961-6. PMID 5025637 DOI: 10.1021/Bi00760A035 |
0.458 |
|
| 1972 |
Huang M, Daly JW. Accumulation of cyclic adenosine monophosphate in incubated slices of brain tissue. 1. Structure-activity relationships of agonists and antagonists of biogenic amines and of tricyclic tranquilizers and antidepressants. Journal of Medicinal Chemistry. 15: 458-62. PMID 4402483 DOI: 10.1021/Jm00275A004 |
0.312 |
|
| 1972 |
Schultz J, Hamprecht B, Daly JW. Accumulation of adenosine 3':5'-cyclic monophosphate in clonal glial cells: labeling of intracellular adenine nucleotides with radioactive adenine. Proceedings of the National Academy of Sciences of the United States of America. 69: 1266-70. PMID 4338586 DOI: 10.1073/Pnas.69.5.1266 |
0.303 |
|
| 1972 |
Oesch F, Waters JA, Daly JW, Witkop B. Fluorescent derivatives of strophanthidin. Interaction with sodium- and potassium-activated adenosine triphosphatase. Journal of Medicinal Chemistry. 15: 757-9. PMID 4261402 DOI: 10.1021/Jm00277A015 |
0.469 |
|
| 1972 |
Daly JW, Jerina DM, Witkop B. Arene oxides and the NIH shift: the metabolism, toxicity and carcinogenicity of aromatic compounds. Experientia. 28: 1129-49. PMID 4117670 DOI: 10.1007/Bf01946135 |
0.585 |
|
| 1972 |
Cannon JF, Daly J, Silverton JV, Boyd DR, Jerina DM. Crystal and molecular structure of cis-2-isopropyl-3-(4-nitrophenyl)-oxaziridine Journal of the Chemical Society-Perkin Transactions 1. 1137-1140. DOI: 10.1039/P29720001137 |
0.434 |
|
| 1972 |
LUTZ WB, CREVELING CR, DALY JW, WITKOP B, GOLDBERG LI. ChemInform Abstract: SCHWEFEL-ANALOGA VON DOPAMIN UND NOREPINEPHRIN, INHIBIERUNG DER CATECHOL-O-METHYL-TRANSFERASE Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/Chin.197248266 |
0.456 |
|
| 1972 |
OESCH F, WATERS JA, DALY JW, WITKOP B. ChemInform Abstract: FLUORESZIERENDE DERIVATE DES STROPHANTHIDINS, DIE WECHSELWIRKUNG MIT NATRIUM- UND KALIUMAKTIVIERTER ADENOSINTRIPHOSPHATASE Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/Chin.197246432 |
0.45 |
|
| 1972 |
CANNON JF, DALY J, SILVERTON JV, BOYD DR, JERINA DM. ChemInform Abstract: KRISTALL- UND MOLEKULARSTRUKTUR VON CIS-2-ISOPROPYL-3-(4-NITRO-PHENYL)-OXAZIRIDIN Chemischer Informationsdienst. 3. DOI: 10.1002/Chin.197239096 |
0.436 |
|
| 1971 |
Jerina DM, Daly JW, Jeffrey AM, Gibson DT. Cis-1,2-dihydroxy-1,2-dihydronaphthalene: a bacterial metabolite from naphthalene. Archives of Biochemistry and Biophysics. 142: 394-6. PMID 5545490 DOI: 10.1016/0003-9861(71)90298-0 |
0.427 |
|
| 1971 |
Jerina DM, Daly JW, Witkop B. Migration of substituents during Hydroxylation of aromatic substrates (NIH shift). Oxidations with peroxytrifluoroacetic acid. Biochemistry. 10: 366-72. PMID 5543961 DOI: 10.1021/Bi00779A002 |
0.586 |
|
| 1971 |
Daly JW, Karle I, Myers CW, Tokuyama T, Waters JA, Witkop B. Histrionicotoxins: roentgen-ray analysis of the novel allenic and acetylenie spiroalkaloids isolated from a Colombian frog, Dendrobates histrionicus. Proceedings of the National Academy of Sciences of the United States of America. 68: 1870-5. PMID 5288773 DOI: 10.1073/Pnas.68.8.1870 |
0.468 |
|
| 1971 |
Daly J, Witkop B. Batrachotoxin, an extremely active cardio- and neurotoxin from the Colombian arrow poison frog Phyllobates aurotaenia. Clinical Toxicology. 4: 331-42. PMID 4363503 DOI: 10.3109/15563657108990484 |
0.381 |
|
| 1971 |
Oesch E, Jerina DM, Daly J. A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide. Biochimica Et Biophysica Acta. 227: 685-91. PMID 4328054 DOI: 10.1016/0005-2744(71)90017-9 |
0.484 |
|
| 1971 |
Albuquerque EX, Daly JW, Witkop B. Batrachotoxin: chemistry and pharmacology. Science (New York, N.Y.). 172: 995-1002. PMID 4324825 DOI: 10.1126/Science.172.3987.995 |
0.476 |
|
| 1971 |
ALBUQUERQUE EX, DALY JW, WITKOP B. ChemInform Abstract: BATRACHOTOXIN, CHEMIE UND PHARMAKOLOGIE Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197141380 |
0.438 |
|
| 1970 |
Daly JW, Jerina DM. Aerobic aromatic hydroxylation catalyzed by horseradish peroxidase: absense of NIH shift. Biochimica Et Biophysica Acta. 208: 340-2. PMID 5420986 DOI: 10.1016/0304-4165(70)90256-4 |
0.468 |
|
| 1970 |
Jerina DM, Daly JW, Witkop B, Zaltzman-Nirenberg P, Udenfriend S. 1,2-naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. Biochemistry. 9: 147-56. PMID 5411205 DOI: 10.1021/Bi00803A019 |
0.582 |
|
| 1970 |
Daly JW, Jerina DM, Ziffer H, Witkop B, Klärner FG, Vogel E. Enzymatic hydration of 8,9-indan oxide, Homoallylic addition of water. Journal of the American Chemical Society. 92: 702-3. PMID 5411062 DOI: 10.1021/ja00706a048 |
0.517 |
|
| 1970 |
Usubillaga A, Seelkopf C, Karle IL, Daly JW, Witkop B. The structure of solaphyllidine, a novel 4-ketosteroidal alkaloid. Journal of the American Chemical Society. 92: 700-1. PMID 5411061 DOI: 10.1021/Ja00706A047 |
0.444 |
|
| 1970 |
Shimizu H, Creveling CR, Daly J. Stimulated formation of adenosine 3',5'-cyclic phosphate in cerebral cortex: synergism between electrical activity and biogenic amines. Proceedings of the National Academy of Sciences of the United States of America. 65: 1033-40. PMID 4314898 DOI: 10.1073/Pnas.65.4.1033 |
0.301 |
|
| 1970 |
Boyd DR, Jerina DM, Daly JW. Optically active 1,2-naphthalene oxide The Journal of Organic Chemistry. 35: 3170-3172. DOI: 10.1021/Jo00834A076 |
0.44 |
|
| 1970 |
Jerina DM, Ziffer H, Daly JW. Role of the arene oxide-oxepin system in the metabolism of aromatic substrates. IV. Stereochemical considerations of dihydrodiol formation and dehyrogenation Journal of the American Chemical Society. 92: 1056-1061. DOI: 10.1021/Ja00707A052 |
0.462 |
|
| 1970 |
Jerina DM, Boyd DR, Daly JW. Photolysis of pyridine-N-oxide: an oxygen atom transfer model for enzymatic oxygenation, arene oxide formation, and the NIH shift Tetrahedron Letters. 11: 457-460. DOI: 10.1016/0040-4039(70)80074-0 |
0.448 |
|
| 1970 |
BOYD DR, JERINA DM, DALY JW. ChemInform Abstract: OPTISCH AKTIVES 1,2-NAPHTHALIN-OXID Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197049305 |
0.449 |
|
| 1970 |
JERINA DM, BOYD DR, DALY JW. ChemInform Abstract: PHOTOLYSE VON PYRIDIN-N-OXID, MODELL FUER DIE TRANSFER-RK. VON SAUERSTOFF BEI ENZYMRK., DIE BLDG. VON AREN-OXIDEN SOWIE DIE ′NIH-SHIFTS′ Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197019210 |
0.453 |
|
| 1970 |
USUBILLAGA A, SEELKOPF C, KARLE IL, DALY JW, WITKOP B. ChemInform Abstract: STRUKTUR VON SOLAPHYLLIDIN, EINEM 4-KETO-STEROIDALKALOID Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197018420 |
0.447 |
|
| 1970 |
DALY JW, TOKUYAMA T, HABERMEHL G, KARLE IL, WITKOP B. ChemInform Abstract: FROSCHGIFTE, ISOLIERUNG UND STRUKTUR VON PUMILIOTOXIN C Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197011345 |
0.437 |
|
| 1969 |
Tokuyama T, Daly J, Witkop B. The structure of batrachotoxin, a steroidal alkaloid from the Colombian arrow poison frog, Phyllobates aurotaenia, and partial synthesis of batrachotoxin and its analogs and homologs. Journal of the American Chemical Society. 91: 3931-8. PMID 5814950 DOI: 10.1021/Ja01042A042 |
0.409 |
|
| 1969 |
Karle IL, Daly JW, Witkop B. 2,3-cis-3,4-trans-3,4-dihydroxy-L-proline: mass spectrometry and X-ray analysis. Science (New York, N.Y.). 164: 1401-2. PMID 5783710 DOI: 10.1126/Science.164.3886.1401 |
0.447 |
|
| 1969 |
Daly J, Jerina D, Farnsworth J, Guroff G. The migration of deuterium during aryl hydroxylation. II. Effect of induction of microsomal hydroxylases with phenobarbital or polycyclic aromatic hydrocarbons. Archives of Biochemistry and Biophysics. 131: 238-44. PMID 5781725 DOI: 10.1016/0003-9861(69)90127-1 |
0.473 |
|
| 1969 |
Creveling CR, Daly JW, Tokuyama T, Witkop B. Labile lipophilic derivatives of norepinephrine capable of crossing the blood-brain barrier. Experientia. 25: 26-7. PMID 5766567 DOI: 10.1007/Bf01903871 |
0.47 |
|
| 1969 |
Daly JW, Tokuyama T, Habermehl G, Karle I, Witkop B. [Frog venoms. Isolation and structure of pumiliotoxin]. Justus Liebigs Annalen Der Chemie. 729: 198-204. PMID 5364747 DOI: 10.1002/Jlac.19697290124 |
0.476 |
|
| 1969 |
Daly J, Jerina D. Migration of deuterium during aryl hydroxylation. 3. Effect of ortho- and meta- substituents. Archives of Biochemistry and Biophysics. 134: 266-8. PMID 5345594 DOI: 10.1016/0003-9861(69)90280-X |
0.46 |
|
| 1968 |
Daly JW, Guroff G, Jerina DM, Udenfriend S, Witkop B. Intramolecular migrations of aryl substituents during enzymatic hydroxylation. Hoppe-Seyler's Zeitschrift Fã¼R Physiologische Chemie. 349: 1600-4. PMID 5745910 |
0.405 |
|
| 1968 |
Spector S, Tabei R, Creveling CR, Daly JW, Witkop B, Sjoerdsma A. Reduction of tissue norepinephrine and blood pressure by 3,5-dihydroxy-4-methoxy-phenylalanine. Life Sciences. 7: 943-9. PMID 5735321 DOI: 10.1016/0024-3205(68)90100-8 |
0.468 |
|
| 1968 |
Daly J, Jerina D, Witkop B. Migration of deuterium during hydroxylation of aromatic substrates by liver microsomes. I. Influence of ring substitutents. Archives of Biochemistry and Biophysics. 128: 517-27. PMID 5698035 DOI: 10.1016/0003-9861(68)90059-3 |
0.591 |
|
| 1968 |
Tokuyama T, Daly J, Witkop B, Karle IL, Karle J. The structure of batrachotoxinin A, a novel steroidal alkaloid from the Colombian arrow poison frog, Phyllobates aurotaenia. Journal of the American Chemical Society. 90: 1917-8. PMID 5689118 DOI: 10.1021/Ja01009A052 |
0.454 |
|
| 1968 |
Jerina DM, Daly JW, Witkop B, Zaltzman-Nirenberg P, Udenfriend S. The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. 3. Formation of 1,2-naphthalene oxide from naphthalene by liver microsomes. Journal of the American Chemical Society. 90: 6525-7. PMID 5682453 DOI: 10.1021/Ja01025A058 |
0.582 |
|
| 1968 |
Jerina DM, Daly JW, Witkop B. The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. II. Synthesis of 3,4-toluene-4-2H oxide and subsequent "NIH shift" to 4-hydroxytoluene-3-2H. Journal of the American Chemical Society. 90: 6523-5. PMID 5682452 DOI: 10.1021/Ja01025A057 |
0.593 |
|
| 1968 |
Jerina D, Guroff G, Daly J. Enzymic and nonenzymic hydroxylation and chlorination of p-deuteroanisole. Archives of Biochemistry and Biophysics. 124: 612-5. PMID 5661630 DOI: 10.1016/0003-9861(68)90374-3 |
0.437 |
|
| 1968 |
Axelrod J, Daly J. Phenol-O-methyltransferase Bba - Enzymology. 159: 472-478. PMID 5657870 DOI: 10.1016/0005-2744(68)90131-9 |
0.444 |
|
| 1968 |
Creveling CR, Daly JW, Parfitt RT, Witkop B. The chemorelease of norepinephrine from mouse hearts. IV. Structure-activity relationships. Reserpines and yohimbines. Journal of Medicinal Chemistry. 11: 596-8. PMID 5656504 DOI: 10.1021/Jm00309A041 |
0.451 |
|
| 1968 |
Creveling CR, Daly JW, Witkop B. The chemorelease of norepinephrine from mouse hearts. 3. 3,5-Dihydroxy-4-methoxyphenethylamines and related compounds. Journal of Medicinal Chemistry. 11: 595-6. PMID 5656503 DOI: 10.1021/Jm00309A040 |
0.449 |
|
| 1968 |
Creveling CR, Daly J, Tokuyama T, Witkop B. The combined use of alpha-methyltyrosine and threo-dihydroxyphenylserine--selective reduction of dopamine levels in the central nervous system. Biochemical Pharmacology. 17: 65-70. PMID 5638559 DOI: 10.1016/0006-2952(68)90158-5 |
0.469 |
|
| 1968 |
Daly JW, Guroff G, Udenfriend S, Witkop B. Hydroxylation of alkyl and halogen substituted anilines and acetanilides by microsomal hydroxylases. Biochemical Pharmacology. 17: 31-6. PMID 5638557 DOI: 10.1016/0006-2952(68)90154-8 |
0.514 |
|
| 1968 |
Jerina DM, Daly JW, Witkop B. Additions and Corrections - Deuterium Migration during the Acid-Catalyzed Dehydration of 6-Deutrio-5,6-dihydroxy-3-chloro-1,3-cyclohexadiene, a Nonenzymatic Model for the NIH Shift. Journal of the American Chemical Society. 90: 1094-1094. DOI: 10.1021/Ja01006A609 |
0.444 |
|
| 1968 |
Jerina D, Daly J, Witkop B, Zaltzman-Nirenberg P, Udenfriend S. Role of the arene oxide-oxepin system in the metabolism of aromatic substrates Archives of Biochemistry and Biophysics. 128: 176-183. DOI: 10.1016/0003-9861(68)90020-9 |
0.6 |
|
| 1967 |
Daly J, Guroff G, Udenfriend S, Witkop B. Hydroxylation-induced migrations of tritium in several substrates of liver aryl hydroxylases. Archives of Biochemistry and Biophysics. 122: 218-23. PMID 6076218 DOI: 10.1016/0003-9861(67)90142-7 |
0.501 |
|
| 1967 |
Creveling CR, Daly JW, Witkop B. The depletion of cardiac norepinephrine by 3,5-dihydroxy-4-methoxyphenethylamine and related compounds. The Journal of Pharmacology and Experimental Therapeutics. 158: 46-54. PMID 6054080 |
0.375 |
|
| 1967 |
Levitt M, Gibb JW, Daly JW, Lipton M, Udenfriend S. A new class of tyrosine hydroxylase inhibitors and a simple assay of inhibition in vivo. Biochemical Pharmacology. 16: 1313-21. PMID 6053599 DOI: 10.1016/0006-2952(67)90162-1 |
0.304 |
|
| 1967 |
Guroff G, Daly JW, Jerina DM, Renson J, Witkop B, Udenfriend S. Hydroxylation-induced migration: the NIH shift. Recent experiments reveal an unexpected and general result of enzymatic hydroxylation of aromatic compounds. Science (New York, N.Y.). 157: 1524-30. PMID 6038165 DOI: 10.1126/Science.157.3796.1524 |
0.583 |
|
| 1967 |
Udenfriend S, Zaltzman-Nirenberg P, Daly J, Guroff G, Chidsey C, Witkop B. Intramolecular migration of deuterium and tritium during enzymic hydroxylation of p-deuteroacetanilide and p-tritioacetanilide. Archives of Biochemistry and Biophysics. 120: 413-9. PMID 6033457 DOI: 10.1016/0003-9861(67)90258-5 |
0.465 |
|
| 1967 |
Daly JW, Witkop B. Selective exchange of nuclear protons in hydroxyindoles. Journal of the American Chemical Society. 89: 1032-3. PMID 5298577 |
0.354 |
|
| 1967 |
Daly JW, Mauger AB, Yonemitsu O, Antonov VK, Takase K, Witkop B. The synthesis and metabolism of 2,3-dihydro-L-tryptophan and 2,3-dihydro-5-hydroxy-DL-tryptophan. Biochemistry. 6: 648-54. PMID 5297946 DOI: 10.1021/Bi00855A002 |
0.387 |
|
| 1967 |
Jerina DM, Daly JW, Witkop B. Deuterium migration during the acid-catalyzed dehydration of 6-deuterio-5,6-dihydroxy-3-chloro-1,3-cyclohexadi-ene, a nonenzymic model for the NIH shift Journal of the American Chemical Society. 89: 5488-5489. DOI: 10.1021/Ja00997A053 |
0.565 |
|
| 1967 |
Jerina DM, Daly JW, Landis WR, Witkop B, Udenfriend S. Intramolecular migration of tritium and deuterium during nonenzymic aromatic hydroxylation Journal of the American Chemical Society. 89: 3347-3349. DOI: 10.1021/Ja00989A044 |
0.571 |
|
| 1966 |
Creveling CR, Daly JW, Witkop B. The depletion of norepinephrine-3H from heart by alpha-methyl-m-tyrosine. A novel and convenient method for assaying the inhibition of aromatic amino acid decarboxylase in vivo. Journal of Medicinal Chemistry. 9: 284-6. PMID 5960888 DOI: 10.1021/Jm00321A003 |
0.479 |
|
| 1966 |
Daly JW, Creveling CR, Witkop B. The chemorelease of norepinephrine from mouse hearts. Structure-activity relationships. I. Sympathomimetic and related amines. Journal of Medicinal Chemistry. 9: 273-80. PMID 5960887 |
0.381 |
|
| 1966 |
Inscoe JK, Daly J, Axelrod J. Factors affecting the enzymatic formation of O-methylated dihydroxy derivatives. Biochemical Pharmacology. 14: 1257-63. PMID 5323463 DOI: 10.1016/0006-2952(65)90303-5 |
0.452 |
|
| 1966 |
Daly JW, Creveling CR, Witkop B. The chemorelease of norepinephrine in mouse hearts. Structure-activity relationships. II. Drugs affecting the sympathetic and central nervous systems Journal of Medicinal Chemistry. 9: 280-284. PMID 4381277 DOI: 10.1021/JM00321A002 |
0.375 |
|
| 1966 |
Renson J, Daly J, Weissbach H, Witkop B, Udenfriend S. Enzymatic conversion of 5-tritiotryptophan to 4-tritio-5-hydroxytryptophan Biochemical and Biophysical Research Communications. 25: 504-513. DOI: 10.1016/0006-291X(66)90620-6 |
0.438 |
|
| 1965 |
Axelrod J, Daly J. Pituitary gland: Enzymic formation of methanol from S-adenosylmethionine Science. 150: 892-893. PMID 5835789 DOI: 10.1126/Science.150.3698.892 |
0.405 |
|
| 1965 |
Daly JW, Witkop B, Bommer P, Biemann K. Batrachotoxin. The active principle of the Colombian arrow poison frog, Phyllobates bicolor [6] Journal of the American Chemical Society. 87: 124-126. PMID 5826972 DOI: 10.1021/Ja01079A026 |
0.375 |
|
| 1965 |
Joshi BC, May EL, Fales HM, Daly JW, Jacobson AE. Constitution and analgetic activity of a new product in the benzomorphan synthesis Journal of Medicinal Chemistry. 8: 559-563. DOI: 10.1021/Jm00329A002 |
0.417 |
|
| 1965 |
Daly JW, Benigni J, Minnis R, Kanaoka Y, Witkop B. Synthesis and metabolism of 6-hydroxycatecholamines Biochemistry. 4: 2513-2525. DOI: 10.1021/Bi00887A035 |
0.453 |
|
| 1963 |
Daly JW, Witkop B. Recent Studies on the Centrally Active Endogenous Amines Angewandte Chemie International Edition in English. 2: 421-440. DOI: 10.1002/Anie.196304211 |
0.397 |
|
| 1963 |
Daly JW, Witkop B. Neuere Untersuchungen über zentral wirkende endogene endogene Amine Angewandte Chemie. 75: 552-572. DOI: 10.1002/Ange.19630751207 |
0.362 |
|
| 1962 |
Axelrod J, Daly J. The enzymic conversion of adenine to 3-methyladenine Bba Specialized Section On Nucleic Acids and Related Subjects. 61: 855-856. PMID 13965707 DOI: 10.1016/0926-6550(62)90077-4 |
0.401 |
|
| 1962 |
Daly JW, Witkop B. The Synthesis and Properties of N,N-Dialkylaminovinylindoles The Journal of Organic Chemistry. 27: 4104-4106. DOI: 10.1021/JO01058A536 |
0.371 |
|
| 1961 |
Daly J, Horner L, Witkop B. Chemical and Enzymatic Routes to Methoxydopamines Journal of the American Chemical Society. 83: 4787-4792. DOI: 10.1021/Ja01484A022 |
0.44 |
|
| 1960 |
DALY JW, AXELROD J, WITKOP B. Dynamic aspects of enzymatic O-methylation and -demethylation of catechols in vitro and in vivo. The Journal of Biological Chemistry. 235: 1155-9. PMID 13813871 |
0.328 |
|
| 1960 |
Daly J, Durant RC, Friess SL, Holland GF, Kny H, Witkop B. Labilization of Ester Bonds in Aminocyclitol Derivatives. II. Polyacetates of Deoxystreptamine1 Journal of the American Chemical Society. 82: 5928-5934. DOI: 10.1021/Ja01507A033 |
0.443 |
|
| 1960 |
Cohen LA, Daly JW, Kny H, Witkop B. Nuclear Magnetic Resonance Spectra of Indoles Journal of the American Chemical Society. 82: 2184-2187. DOI: 10.1021/Ja01494A024 |
0.412 |
|
| 1959 |
Senoh S, Daly J, Axelrod J, Witkop B. Enzymatic p-O-Methylation by Catechol O-Methyl Transferase Journal of the American Chemical Society. 81: 6240-6245. DOI: 10.1021/Ja01532A031 |
0.543 |
|
| 1958 |
Daly JW, Green FC, Eastman RH. Sabinene hydrate: A constituent of American peppermint oil Journal of the American Chemical Society. 80: 6330-6336. DOI: 10.1021/Ja01556A042 |
0.555 |
|
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