Rebecca B. Riggins, Ph.D. - Publications

Affiliations: 
2003 University of Virginia, Charlottesville, VA 
Area:
Microbiology Biology, Cell Biology, Molecular Biology, Oncology

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Madhavan S, Gusev Y, Singh S, Riggins RB. ERRγ target genes are poor prognostic factors in Tamoxifen-treated breast cancer. Journal of Experimental & Clinical Cancer Research : Cr. 34: 45. PMID 25971350 DOI: 10.1186/s13046-015-0150-9  0.8
2015 Schwartz-Roberts JL, Cook KL, Chen C, Shajahan-Haq AN, Axelrod M, Wärri A, Riggins RB, Jin L, Haddad BR, Kallakury BV, Baumann WT, Clarke R. Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate. Cancer Research. 75: 1046-55. PMID 25576084 DOI: 10.1158/0008-5472.CAN-14-1851  0.8
2015 Heckler MM, Riggins RB. ERRβ splice variants differentially regulate cell cycle progression. Cell Cycle (Georgetown, Tex.). 14: 31-45. PMID 25496115 DOI: 10.4161/15384101.2014.972886  0.8
2015 Hu R, Warri A, Jin L, Zwart A, Riggins RB, Fang HB, Clarke R. NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer. Molecular and Cellular Biology. 35: 379-90. PMID 25368386 DOI: 10.1128/MCB.00847-14  0.8
2014 Heckler MM, Thakor H, Schafer CC, Riggins RB. ERK/MAPK regulates ERRγ expression, transcriptional activity and receptor-mediated tamoxifen resistance in ER+ breast cancer. The Febs Journal. 281: 2431-42. PMID 24684682 DOI: 10.1111/febs.12797  0.8
2013 Chen X, Xuan J, Wang C, Shajahan AN, Riggins RB, Clarke R. Reconstruction of transcriptional regulatory networks by stability-based network component analysis. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 10: 1347-58. PMID 24407294 DOI: 10.1109/TCBB.2012.146  0.8
2013 Gusev Y, Riggins RB, Bhuvaneshwar K, Gauba R, Sheahan L, Clarke R, Madhavan S. In silico discovery of mitosis regulation networks associated with early distant metastases in estrogen receptor positive breast cancers. Cancer Informatics. 12: 31-51. PMID 23470717 DOI: 10.4137/CIN.S10329  0.8
2013 Chen L, Xuan J, Riggins RB, Wang Y, Clarke R. Identifying protein interaction subnetworks by a bagging Markov random field-based method. Nucleic Acids Research. 41: e42. PMID 23161673 DOI: 10.1093/nar/gks951  0.8
2012 Yenugonda VM, Kong Y, Deb TB, Yang Y, Riggins RB, Brown ML. Trans-resveratrol boronic acid exhibits enhanced anti-proliferative activity on estrogen-dependent MCF-7 breast cancer cells. Cancer Biology & Therapy. 13: 925-34. PMID 22785207 DOI: 10.4161/cbt.20845  0.8
2012 Gu J, Xuan J, Riggins RB, Chen L, Wang Y, Clarke R. Robust identification of transcriptional regulatory networks using a Gibbs sampler on outlier sum statistic. Bioinformatics (Oxford, England). 28: 1990-7. PMID 22595208 DOI: 10.1093/bioinformatics/bts296  0.8
2012 Chen X, Wang C, Shajahan AN, Riggins RB, Clarke R, Xuan J. Reconstruction of transcription regulatory networks by stability-based network component analysis Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7292: 36-47. DOI: 10.1007/978-3-642-30191-9_4  0.8
2011 Chen L, Xuan J, Riggins RB, Clarke R, Wang Y. Identifying cancer biomarkers by network-constrained support vector machines. Bmc Systems Biology. 5: 161. PMID 21992556 DOI: 10.1186/1752-0509-5-161  0.8
2011 Madhavan S, Gusev Y, Harris M, Tanenbaum DM, Gauba R, Bhuvaneshwar K, Shinohara A, Rosso K, Carabet LA, Song L, Riggins RB, Dakshanamurthy S, Wang Y, Byers SW, Clarke R, et al. G-DOC: a systems medicine platform for personalized oncology. Neoplasia (New York, N.Y.). 13: 771-83. PMID 21969811 DOI: 10.1593/neo.11806  0.8
2011 Gong T, Xuan J, Chen L, Riggins RB, Li H, Hoffman EP, Clarke R, Wang Y. Motif-guided sparse decomposition of gene expression data for regulatory module identification. Bmc Bioinformatics. 12: 82. PMID 21426557 DOI: 10.1186/1471-2105-12-82  0.8
2010 Riggins RB, Mazzotta MM, Maniya OZ, Clarke R. Orphan nuclear receptors in breast cancer pathogenesis and therapeutic response. Endocrine-Related Cancer. 17: R213-31. PMID 20576803 DOI: 10.1677/ERC-10-0058  0.8
2010 Ning Y, Riggins RB, Mulla JE, Chung H, Zwart A, Clarke R. IFNgamma restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-kappaB, BCL2 family members, and signaling to caspase-dependent apoptosis. Molecular Cancer Therapeutics. 9: 1274-85. PMID 20457620 DOI: 10.1158/1535-7163.MCT-09-1169  0.8
2010 Chen L, Xuan J, Riggins RB, Wang Y, Hoffman EP, Clarke R. Multilevel support vector regression analysis to identify condition-specific regulatory networks. Bioinformatics (Oxford, England). 26: 1416-22. PMID 20375112 DOI: 10.1093/bioinformatics/btq144  0.8
2010 Nehra R, Riggins RB, Shajahan AN, Zwart A, Crawford AC, Clarke R. BCL2 and CASP8 regulation by NF-kappaB differentially affect mitochondrial function and cell fate in antiestrogen-sensitive and -resistant breast cancer cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2040-55. PMID 20154269 DOI: 10.1096/fj.09-138305  0.8
2010 Crawford AC, Riggins RB, Shajahan AN, Zwart A, Clarke R. Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis. Plos One. 5: e8604. PMID 20062536 DOI: 10.1371/journal.pone.0008604  0.8
2010 Cavalli LR, Riggins RB, Wang A, Clarke R, Haddad BR. Frequent loss of heterozygosity at the interferon regulatory factor-1 gene locus in breast cancer. Breast Cancer Research and Treatment. 121: 227-31. PMID 19697121 DOI: 10.1007/s10549-009-0509-8  0.8
2010 Gu J, Xuan J, Wang Y, Riggins RB, Clarke R. Identification of transcriptional regulatory networks by learning the marginal function of outlier sum statistic Proceedings - 9th International Conference On Machine Learning and Applications, Icmla 2010. 281-286. DOI: 10.1109/ICMLA.2010.48  0.8
2009 Chen L, Xuan J, Wang Y, Hoffman EP, Riggins RB, Clarke R. Identification of condition-specific regulatory modules through multi-level motif and mRNA expression analysis. International Journal of Computational Biology and Drug Design. 2: 1-20. PMID 20054984 DOI: 10.1504/IJCBDD.2009.027582  0.8
2009 Shajahan AN, Riggins RB, Clarke R. The role of X-box binding protein-1 in tumorigenicity. Drug News & Perspectives. 22: 241-6. PMID 19609461 DOI: 10.1358/dnp.2009.22.5.1378631  0.8
2009 Clarke R, Shajahan AN, Riggins RB, Cho Y, Crawford A, Xuan J, Wang Y, Zwart A, Nehra R, Liu MC. Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 114: 8-20. PMID 19444933 DOI: 10.1016/j.jsbmb.2008.12.023  0.8
2009 Zhang B, Li H, Riggins RB, Zhan M, Xuan J, Zhang Z, Hoffman EP, Clarke R, Wang Y. Differential dependency network analysis to identify condition-specific topological changes in biological networks. Bioinformatics (Oxford, England). 25: 526-32. PMID 19112081 DOI: 10.1093/bioinformatics/btn660  0.8
2008 Riggins RB, Lan JP, Zhu Y, Klimach U, Zwart A, Cavalli LR, Haddad BR, Chen L, Gong T, Xuan J, Ethier SP, Clarke R. ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer. Cancer Research. 68: 8908-17. PMID 18974135 DOI: 10.1158/0008-5472.CAN-08-2669  0.8
2008 Chen L, Xuan J, Wang Y, Riggins RB, Clarke R. Network-constrained support vector machine for classification Proceedings - 7th International Conference On Machine Learning and Applications, Icmla 2008. 60-65. DOI: 10.1109/ICMLA.2008.55  0.8
2008 Gong T, Xuan J, Chen L, Riggins RB, Wang Y, Hoffman EP, Clarke R. Sparse decomposition of gene expression data to infer transcriptional modules guided by motif information Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4983: 244-255. DOI: 10.1007/978-3-540-79450-9_23  0.8
2008 Gong T, Xuan J, Riggins RB, Wang Y, Hoffman EP, Clarke R. Exploring transcriptional modules through integrative gene clustering guided by transcription factor binding information Proceedings of the 2008 International Conference On Bioinformatics and Computational Biology, Biocomp 2008. 191-197.  0.8
2008 Chen L, Xuan J, Riggins RB, Wang Y, Hoffman EP, Clarke R. Identification of condition-specific regulatory modules by multi-level motif and mRNA expression analysis Proceedings of the 2008 International Conference On Bioinformatics and Computational Biology, Biocomp 2008. 23-28.  0.8
2007 Gomez BP, Riggins RB, Shajahan AN, Klimach U, Wang A, Crawford AC, Zhu Y, Zwart A, Wang M, Clarke R. Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 4013-27. PMID 17660348 DOI: 10.1096/fj.06-7990com  0.8
2007 Schrecengost RS, Riggins RB, Thomas KS, Guerrero MS, Bouton AH. Breast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane ruffling. Cancer Research. 67: 6174-82. PMID 17616674 DOI: 10.1158/0008-5472.CAN-06-3455  0.8
2007 Bouker KB, Skaar TC, Harburger DS, Riggins RB, Fernandez DR, Zwart A, Clarke R. The A4396G polymorphism in interferon regulatory factor 1 is frequently expressed in breast cancer cell lines. Cancer Genetics and Cytogenetics. 175: 61-4. PMID 17498560 DOI: 10.1016/j.cancergencyto.2006.12.008  0.8
2007 Riggins RB, Schrecengost RS, Guerrero MS, Bouton AH. Pathways to tamoxifen resistance. Cancer Letters. 256: 1-24. PMID 17475399 DOI: 10.1016/j.canlet.2007.03.016  0.8
2006 Riggins RB, Thomas KS, Ta HQ, Wen J, Davis RJ, Schuh NR, Donelan SS, Owen KA, Gibson MA, Shupnik MA, Silva CM, Parsons SJ, Clarke R, Bouton AH. Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b. Cancer Research. 66: 7007-15. PMID 16849545 DOI: 10.1158/0008-5472.CAN-05-3952  0.8
2005 Riggins RB, Bouton AH, Liu MC, Clarke R. Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer. Vitamins and Hormones. 71: 201-37. PMID 16112269 DOI: 10.1016/S0083-6729(05)71007-4  0.8
2005 Bouker KB, Skaar TC, Riggins RB, Harburger DS, Fernandez DR, Zwart A, Wang A, Clarke R. Interferon regulatory factor-1 (IRF-1) exhibits tumor suppressor activities in breast cancer associated with caspase activation and induction of apoptosis. Carcinogenesis. 26: 1527-35. PMID 15878912 DOI: 10.1093/carcin/bgi113  0.8
2005 Riggins RB, Zwart A, Nehra R, Clarke R. The nuclear factor kappa B inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells. Molecular Cancer Therapeutics. 4: 33-41. PMID 15657351  0.8
2004 Bouker KB, Skaar TC, Fernandez DR, O'Brien KA, Riggins RB, Cao D, Clarke R. interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (faslodex, fulvestrant). Cancer Research. 64: 4030-9. PMID 15173018 DOI: 10.1158/0008-5472.CAN-03-3602  0.8
2003 Riggins RB, Quilliam LA, Bouton AH. Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3. The Journal of Biological Chemistry. 278: 28264-73. PMID 12740391 DOI: 10.1074/jbc.M303535200  0.8
2003 Riggins RB, DeBerry RM, Toosarvandani MD, Bouton AH. Src-dependent association of Cas and p85 phosphatidylinositol 3'-kinase in v-crk-transformed cells. Molecular Cancer Research : McR. 1: 428-37. PMID 12692262  0.8
2001 Bouton AH, Riggins RB, Bruce-Staskal PJ. Functions of the adapter protein Cas: signal convergence and the determination of cellular responses. Oncogene. 20: 6448-58. PMID 11607844 DOI: 10.1038/sj.onc.1204785  0.8
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