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Year Citation  Score
2024 Smoom R, May CL, Skordalakes E, Kaestner KH, Tzfati Y. Separation of telomere protection from length regulation by two different point mutations at amino acid 492 of RTEL1. Biorxiv : the Preprint Server For Biology. PMID 38464183 DOI: 10.1101/2024.02.26.582005  0.365
2023 Hourvitz N, Awad A, Tzfati Y. The many faces of the helicase RTEL1 at telomeres and beyond. Trends in Cell Biology. PMID 37532653 DOI: 10.1016/j.tcb.2023.07.002  0.39
2022 Al-Shareef W, Brown Y, Bryan C, Shuvaeva E, Bsoul S, Greenman R, Kabaha MM, Ulyanov NB, Skordalakes E, Tzfati Y. Functional Interactions of Telomerase Reverse Transcriptase with the Three-Way Junction and the Template Domains of Telomerase RNA. International Journal of Molecular Sciences. 23. PMID 36142669 DOI: 10.3390/ijms231810757  0.574
2020 Kabaha MM, Tzfati Y. Telomerase, the recombination machinery and Rap1 play redundant roles in yeast telomere protection. Current Genetics. PMID 33156376 DOI: 10.1007/s00294-020-01125-4  0.431
2020 Awad A, Glousker G, Lamm N, Tawil S, Hourvitz N, Smoom R, Revy P, Tzfati Y. Full length RTEL1 is required for the elongation of the single-stranded telomeric overhang by telomerase. Nucleic Acids Research. PMID 32542379 DOI: 10.1093/Nar/Gkaa503  0.487
2019 Červenák F, Juríková K, Devillers H, Kaffe B, Khatib A, Bonnell E, Sopkovičová M, Wellinger RJ, Nosek J, Tzfati Y, Neuvéglise C, Tomáška Ľ. Identification of telomerase RNAs in species of the Yarrowia clade provides insights into the co-evolution of telomerase, telomeric repeats and telomere-binding proteins. Scientific Reports. 9: 13365. PMID 31527614 DOI: 10.1038/S41598-019-49628-6  0.543
2018 Klebanov-Akopyan O, Mishra A, Glousker G, Tzfati Y, Shlomai J. Trypanosoma brucei UMSBP2 is a single-stranded telomeric DNA binding protein essential for chromosome end protection. Nucleic Acids Research. PMID 30007364 DOI: 10.1093/Nar/Gky597  0.488
2018 Porreca RM, Glousker G, Awad A, Matilla Fernandez MI, Gibaud A, Naucke C, Cohen SB, Bryan TM, Tzfati Y, Draskovic I, Londoño-Vallejo A. Human RTEL1 stabilizes long G-overhangs allowing telomerase-dependent over-extension. Nucleic Acids Research. PMID 29522136 DOI: 10.1093/Nar/Gky173  0.446
2018 Palka C, Das R, Tzfati Y, Stone M. Investigating the Function of Conformational Heterogeneity in Telomerase RNA using Multi-dimensional Chemical Mapping and Single-Molecule Spectroscopy Biophysical Journal. 114: 215a. DOI: 10.1016/J.Bpj.2017.11.1201  0.421
2016 Simon AJ, Lev A, Zhang Y, Weiss B, Rylova A, Eyal E, Kol N, Barel O, Cesarkas K, Soudack M, Greenberg-Kushnir N, Rhodes M, Wiest DL, Schiby G, Barshack I, ... ... Tzfati Y, et al. Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects. The Journal of Experimental Medicine. PMID 27432940 DOI: 10.1084/Jem.20151618  0.314
2015 Glousker G, Touzot F, Revy P, Tzfati Y, Savage SA. Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a complex telomere biology disorder. British Journal of Haematology. PMID 25940403 DOI: 10.1111/Bjh.13442  0.407
2013 Deng Z, Glousker G, Molczan A, Fox AJ, Lamm N, Dheekollu J, Weizman OE, Schertzer M, Wang Z, Vladimirova O, Schug J, Aker M, Londoño-Vallejo A, Kaestner KH, Lieberman PM, ... Tzfati Y, et al. Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome. Proceedings of the National Academy of Sciences of the United States of America. 110: E3408-16. PMID 23959892 DOI: 10.1073/Pnas.1300600110  0.453
2013 Cash DD, Cohen-Zontag O, Kim NK, Shefer K, Brown Y, Ulyanov NB, Tzfati Y, Feigon J. Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: 10970-5. PMID 23776224 DOI: 10.1073/Pnas.1309590110  0.616
2013 Kuprys PV, Davis SM, Hauer TM, Meltser M, Tzfati Y, Kirk KE. Identification of telomerase RNAs from filamentous fungi reveals conservation with vertebrates and yeasts. Plos One. 8: e58661. PMID 23555591 DOI: 10.1371/Journal.Pone.0058661  0.637
2013 Gupta SK, Kolet L, Doniger T, Biswas VK, Unger R, Tzfati Y, Michaeli S. The Trypanosoma brucei telomerase RNA (TER) homologue binds core proteins of the C/D snoRNA family. Febs Letters. 587: 1399-404. PMID 23523918 DOI: 10.1016/J.Febslet.2013.03.017  0.499
2012 Lamm N, Bsoul S, Kabaha MM, Tzfati Y. "Poisoning" yeast telomeres distinguishes between redundant telomere capping pathways. Chromosoma. 121: 613-27. PMID 23052336 DOI: 10.1007/S00412-012-0385-6  0.493
2012 Tzfati Y, Chen JJL. Telomerase RNA: Structure, Function, and Molecular Mechanisms Telomerases: Chemistry, Biology, and Clinical Applications. 23-51. DOI: 10.1002/9781118268667.ch2  0.451
2011 Raichlin S, Sharon E, Freeman R, Tzfati Y, Willner I. Electron-transfer quenching of nucleic acid-functionalized CdSe/ZnS quantum dots by doxorubicin: a versatile system for the optical detection of DNA, aptamer-substrate complexes and telomerase activity. Biosensors & Bioelectronics. 26: 4681-9. PMID 21684146 DOI: 10.1016/J.Bios.2011.05.016  0.332
2010 Freeman R, Sharon E, Teller C, Henning A, Tzfati Y, Willner I. DNAzyme-like activity of hemin-telomeric G-quadruplexes for the optical analysis of telomerase and its inhibitors. Chembiochem : a European Journal of Chemical Biology. 11: 2362-7. PMID 21031400 DOI: 10.1002/Cbic.201000512  0.325
2010 Sharon E, Freeman R, Riskin M, Gil N, Tzfati Y, Willner I. Optical, electrical and surface plasmon resonance methods for detecting telomerase activity. Analytical Chemistry. 82: 8390-7. PMID 20849086 DOI: 10.1021/Ac101976T  0.343
2010 Freeman R, Sharon E, Teller C, Henning A, Tzfati Y, Willner I. Cover Picture: DNAzyme-Like Activity of Hemin-Telomeric G-Quadruplexes for the Optical Analysis of Telomerase and its Inhibitors (ChemBioChem 17/2010) Chembiochem. 11: 2325-2325. DOI: 10.1002/Cbic.201090082  0.326
2009 Lamm N, Ordan E, Shponkin R, Richler C, Aker M, Tzfati Y. Diminished telomeric 3' overhangs are associated with telomere dysfunction in Hoyeraal-Hreidarsson syndrome. Plos One. 4: e5666. PMID 19461895 DOI: 10.1371/Journal.Pone.0005666  0.461
2009 Gunisova S, Elboher E, Nosek J, Gorkovoy V, Brown Y, Lucier JF, Laterreur N, Wellinger RJ, Tzfati Y, Tomaska L. Identification and comparative analysis of telomerase RNAs from Candida species reveal conservation of functional elements. Rna (New York, N.Y.). 15: 546-59. PMID 19223441 DOI: 10.1261/Rna.1194009  0.538
2008 Kabaha MM, Zhitomirsky B, Schwartz I, Tzfati Y. The 5' arm of Kluyveromyces lactis telomerase RNA is critical for telomerase function. Molecular and Cellular Biology. 28: 1875-82. PMID 18195041 DOI: 10.1128/Mcb.01683-07  0.564
2007 Brown Y, Abraham M, Pearl S, Kabaha MM, Elboher E, Tzfati Y. A critical three-way junction is conserved in budding yeast and vertebrate telomerase RNAs. Nucleic Acids Research. 35: 6280-9. PMID 17855392 DOI: 10.1093/Nar/Gkm713  0.577
2007 Ulyanov NB, Shefer K, James TL, Tzfati Y. Pseudoknot structures with conserved base triples in telomerase RNAs of ciliates. Nucleic Acids Research. 35: 6150-60. PMID 17827211 DOI: 10.1093/Nar/Gkm660  0.591
2007 Hsu M, McEachern MJ, Dandjinou AT, Tzfati Y, Orr E, Blackburn EH, Lue NF. Telomerase core components protect Candida telomeres from aberrant overhang accumulation. Proceedings of the National Academy of Sciences of the United States of America. 104: 11682-7. PMID 17609387 DOI: 10.1073/Pnas.0700327104  0.697
2007 Shefer K, Brown Y, Gorkovoy V, Nussbaum T, Ulyanov NB, Tzfati Y. A triple helix within a pseudoknot is a conserved and essential element of telomerase RNA. Molecular and Cellular Biology. 27: 2130-43. PMID 17210648 DOI: 10.1128/Mcb.01826-06  0.615
2005 Lin J, Ly H, Hussain A, Abraham M, Pearl S, Tzfati Y, Parslow TG, Blackburn EH. Erratum: A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein (Proceedings of the National Academy of Sciences of the United States of America (October 12, 2004) 101, 41 (14713-14718)) Proceedings of the National Academy of Sciences of the United States of America. 102. DOI: 10.1073/Pnas.0506417102  0.612
2004 Lin J, Ly H, Hussain A, Abraham M, Pearl S, Tzfati Y, Parslow TG, Blackburn EH. A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein. Proceedings of the National Academy of Sciences of the United States of America. 101: 14713-8. PMID 15371596 DOI: 10.1073/Pnas.0405879101  0.71
2003 Seto AG, Umansky K, Tzfati Y, Zaug AJ, Blackburn EH, Cech TR. A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity. Rna (New York, N.Y.). 9: 1323-32. PMID 14561882 DOI: 10.1261/Rna.5570803  0.694
2003 Tzfati Y, Knight Z, Roy J, Blackburn EH. A novel pseudoknot element is essential for the action of a yeast telomerase. Genes & Development. 17: 1779-88. PMID 12832393 DOI: 10.1101/Gad.1099403  0.697
2002 Seto AG, Livengood AJ, Tzfati Y, Blackburn EH, Cech TR. A bulged stem tethers Est1p to telomerase RNA in budding yeast. Genes & Development. 16: 2800-12. PMID 12414733 DOI: 10.1101/Gad.1029302  0.696
2000 Tzfati Y, Fulton TB, Roy J, Blackburn EH. Template boundary in a yeast telomerase specified by RNA structure. Science (New York, N.Y.). 288: 863-7. PMID 10797010 DOI: 10.1126/Science.288.5467.863  0.703
1998 Tzfati Y, Shlomai J. Genomic organization and expression of the gene encoding the universal minicircle sequence binding protein. Molecular and Biochemical Parasitology. 94: 137-41. PMID 9719518 DOI: 10.1016/S0166-6851(98)00052-8  0.301
1995 Silberstein Z, Tzfati Y, Cohen A. Primary products of break-induced recombination by Escherichia coli RecE pathway. Journal of Bacteriology. 177: 1692-8. PMID 7896689 DOI: 10.1128/Jb.177.7.1692-1698.1995  0.381
1995 Tzfati Y, Abeliovich H, Avrahami D, Shlomai J. Universal minicircle sequence binding protein, a CCHC-type zinc finger protein that binds the universal minicircle sequence of trypanosomatids. Purification and characterization. The Journal of Biological Chemistry. 270: 21339-45. PMID 7545668 DOI: 10.1074/Jbc.270.36.21339  0.464
1995 Avrahami D, Tzfati Y, Shlomai J. A single-stranded DNA binding protein binds the origin of replication of the duplex kinetoplast DNA. Proceedings of the National Academy of Sciences of the United States of America. 92: 10511-5. PMID 7479830 DOI: 10.1073/Pnas.92.23.10511  0.408
1993 Abeliovich H, Tzfati Y, Shlomai J. A trypanosomal CCHC-type zinc finger protein which binds the conserved universal sequence of kinetoplast DNA minicircles: isolation and analysis of the complete cDNA from Crithidia fasciculata. Molecular and Cellular Biology. 13: 7766-73. PMID 8246992 DOI: 10.1128/Mcb.13.12.7766  0.429
1992 Tzfati Y, Abeliovich H, Kapeller I, Shlomai J. A single-stranded DNA-binding protein from Crithidia fasciculata recognizes the nucleotide sequence at the origin of replication of kinetoplast DNA minicircles. Proceedings of the National Academy of Sciences of the United States of America. 89: 6891-5. PMID 1323120 DOI: 10.1073/Pnas.89.15.6891  0.435
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