Marsha Wills-Karp - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Immunology, Microbiology Biology

142 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Smole U, Gour N, Phelan J, Hofer G, Köhler C, Kratzer B, Tauber PA, Xiao X, Yao N, Dvorak J, Caraballo L, Puerta L, Rosskopf S, Chakir J, Malle E, ... ... Wills-Karp M, et al. Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity. Nature Immunology. 21: 756-765. PMID 32572240 DOI: 10.1038/S41590-020-0698-1  0.39
2020 Wills-Karp M. At last - linking ORMDL3 polymorphisms, decreased sphingolipid synthesis, and asthma susceptibility. The Journal of Clinical Investigation. PMID 31929192 DOI: 10.1172/Jci134333  0.412
2020 DeKruyff RH, Zhang W, Nadeau KC, Leung DYM, Wills-Karp M. Summary of the Keystone Symposium "Origins of Allergic Disease: Microbial, Epithelial and Immune Interactions", March 24-27, Tahoe City, CA. The Journal of Allergy and Clinical Immunology. PMID 31926182 DOI: 10.1016/J.Jaci.2019.11.048  0.336
2018 Gour N, Smole U, Yong HM, Lewkowich IP, Yao N, Singh A, Gabrielson E, Wills-Karp M, Lajoie S. C3a is required for ILC2 function in allergic airway inflammation. Mucosal Immunology. PMID 30104625 DOI: 10.1038/S41385-018-0064-X  0.422
2018 Wills-Karp M. Neutrophil ghosts worsen asthma. Science Immunology. 3. PMID 30076282 DOI: 10.1126/Sciimmunol.Aau0112  0.437
2018 Gour N, Lajoie S, Smole U, White M, Hu D, Goddard P, Huntsman S, Eng C, Mak A, Oh S, Kim JH, Sharma A, Plante S, Salem IH, Resch Y, ... ... Wills-Karp M, et al. Dysregulated invertebrate tropomyosin-dectin-1 interaction confers susceptibility to allergic diseases. Science Immunology. 3. PMID 29475849 DOI: 10.1126/Sciimmunol.Aam9841  0.468
2017 Becerra-Díaz M, Wills-Karp M, Heller NM. New perspectives on the regulation of type II inflammation in asthma. F1000research. 6: 1014. PMID 28721208 DOI: 10.12688/F1000Research.11198.1  0.497
2017 Sussan TE, Sudini K, Talbot CC, Wang X, Wills-Karp M, Burd I, Biswal S. Nrf2 regulates gene-environment interactions in an animal model of intrauterine inflammation: Implications for preterm birth and prematurity. Scientific Reports. 7: 40194. PMID 28071748 DOI: 10.1038/Srep40194  0.327
2016 Hall SL, Baker T, Lajoie S, Richgels PK, Yang Y, McAlees JW, van Lier A, Wills-Karp M, Sivaprasad U, Acciani TH, LeCras TD, Myers JB, Kovacic MB, Lewkowich IP. IL-17A enhances IL-13 activity by enhancing IL-13-induced signal transducer and activator of transcription 6 activation. The Journal of Allergy and Clinical Immunology. PMID 27417023 DOI: 10.1016/J.Jaci.2016.04.037  0.413
2015 Eiymo Mwa Mpollo MS, Brandt EB, Shanmukhappa SK, Arumugam PI, Tiwari S, Loberg A, Pillis D, Rizvi T, Lindsey M, Jonck B, Carmeliet P, Kalra VK, Le Cras TD, Ratner N, Wills-Karp M, et al. Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13. The Journal of Clinical Investigation. PMID 26690703 DOI: 10.1172/Jci77250  0.529
2015 He H, Butz A, Keet CA, Minkovitz CS, Hong X, Caruso DM, Pearson C, Cohen RT, Wills-Karp M, Zuckerman BS, Hughes ME, Wang X. Preterm Birth with Childhood Asthma: The Role of Degree of Prematurity and Asthma Definitions. American Journal of Respiratory and Critical Care Medicine. 192: 520-3. PMID 26278798 DOI: 10.1164/Rccm.201503-0522Le  0.403
2015 Gour N, Wills-Karp M. IL-4 and IL-13 signaling in allergic airway disease. Cytokine. 75: 68-78. PMID 26070934 DOI: 10.1016/J.Cyto.2015.05.014  0.423
2015 Yang L, Lewkowich I, Apsley K, Fritz JM, Wills-Karp M, Weaver TE. Haploinsufficiency for Stard7 is associated with enhanced allergic responses in lung and skin. Journal of Immunology (Baltimore, Md. : 1950). 194: 5635-43. PMID 25980009 DOI: 10.4049/Jimmunol.1500231  0.514
2015 McAlees JW, Lajoie S, Dienger K, Sproles AA, Richgels PK, Yang Y, Khodoun M, Azuma M, Yagita H, Fulkerson PC, Wills-Karp M, Lewkowich IP. Differential control of CD4(+) T-cell subsets by the PD-1/PD-L1 axis in a mouse model of allergic asthma. European Journal of Immunology. 45: 1019-29. PMID 25630305 DOI: 10.1002/Eji.201444778  0.333
2015 McAlees JW, Whitehead GS, Harley IT, Cappelletti M, Rewerts CL, Holdcroft AM, Divanovic S, Wills-Karp M, Finkelman FD, Karp CL, Cook DN. Distinct Tlr4-expressing cell compartments control neutrophilic and eosinophilic airway inflammation. Mucosal Immunology. 8: 863-73. PMID 25465099 DOI: 10.1038/Mi.2014.117  0.451
2015 Eiymo Mwa Mpollo M, Brandt E, Shanmukhappa SK, Arumugam P, Tiwari S, Loberg A, Rizvi T, Lindsey M, Jonckx B, Carmeliet P, Kalra V, Lecras T, Ratner N, wills-Karp M, Khurana hershey G, et al. Placenta Growth Factor Links the IL-13 Response and the Leukotriene Pathway to Augment Airway Hyper-Responsiveness Blood. 126: 977-977. DOI: 10.1182/Blood.V126.23.977.977  0.522
2015 Stoffers SL, Lajoie S, van Lier AG, Zhang X, Sivaprasad U, Kovacic MB, Wills-Karp M, Lewkowich IP. Dissecting Molecular Mechanisms of Synergy Between IL-13 and IL-17A in Severe Asthma Journal of Allergy and Clinical Immunology. 135: AB146. DOI: 10.1016/J.Jaci.2014.12.1416  0.443
2014 Yang D, Sun YY, Bhaumik SK, Li Y, Baumann JM, Lin X, Zhang Y, Lin SH, Dunn RS, Liu CY, Shie FS, Lee YH, Wills-Karp M, Chougnet CA, Kallapur SG, et al. Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16467-81. PMID 25471584 DOI: 10.1523/Jneurosci.2582-14.2014  0.343
2014 Burgess SL, Buonomo E, Carey M, Cowardin C, Naylor C, Noor Z, Wills-Karp M, Petri WA. Bone marrow dendritic cells from mice with an altered microbiota provide interleukin 17A-dependent protection against Entamoeba histolytica colitis. Mbio. 5: e01817. PMID 25370489 DOI: 10.1128/Mbio.01817-14  0.344
2014 Lajoie S, Lewkowich I, Herman NS, Sproles A, Pesce JT, Wynn TA, Grusby MJ, Hamid Q, Wills-Karp M. IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses Clinical and Experimental Allergy. 44: 976-985. PMID 24807637 DOI: 10.1111/Cea.12341  0.498
2014 Sussan TE, Ingole V, Kim JH, McCormick S, Negherbon J, Fallica J, Akulian J, Yarmus L, Feller-Kopman D, Wills-Karp M, Horton MR, Breysse PN, Agrawal A, Juvekar S, Salvi S, et al. Source of biomass cooking fuel determines pulmonary response to household air pollution. American Journal of Respiratory Cell and Molecular Biology. 50: 538-48. PMID 24102120 DOI: 10.1165/Rcmb.2013-0201Oc  0.402
2013 Harley IT, Giles DA, Pfluger PT, Burgess SL, Walters S, Hembree J, Raver C, Rewerts CL, Downey J, Flick LM, Stankiewicz TE, McAlees JW, Wills-Karp M, Balfour Sartor R, Divanovic S, et al. Differential colonization with segmented filamentous bacteria and Lactobacillus murinus do not drive divergent development of diet-induced obesity in C57BL/6 mice. Molecular Metabolism. 2: 171-83. PMID 24049732 DOI: 10.1016/J.Molmet.2013.04.004  0.305
2013 Ziyab AH, Davies GA, Ewart S, Hopkin JM, Schauberger EM, Wills-Karp M, Holloway JW, Arshad SH, Zhang H, Karmaus W. Interactive effect of STAT6 and IL13 gene polymorphisms on eczema status: results from a longitudinal and a cross-sectional study. Bmc Medical Genetics. 14: 67. PMID 23815671 DOI: 10.1186/1471-2350-14-67  0.349
2013 Chen W, Sivaprasad U, Gibson AM, Ericksen MB, Cunningham CM, Bass SA, Kinker KG, Finkelman FD, Wills-Karp M, Khurana Hershey GK. IL-13 receptor α2 contributes to development of experimental allergic asthma. The Journal of Allergy and Clinical Immunology. 132: 951-8.e1-6. PMID 23763980 DOI: 10.1016/J.Jaci.2013.04.016  0.414
2013 Lewkowich IP, Lajoie S, Stoffers SL, Suzuki Y, Richgels PK, Dienger K, Sproles AA, Yagita H, Hamid Q, Wills-Karp M. PD-L2 modulates asthma severity by directly decreasing dendritic cell IL-12 production Mucosal Immunology. 6: 728-739. PMID 23149662 DOI: 10.1038/Mi.2012.111  0.356
2013 Chavez-Valdez R, Kovell L, Ahlawat R, McLemore GL, Wills-Karp M, Gauda EB. Opioids and clonidine modulate cytokine production and opioid receptor expression in neonatal immune cells Journal of Perinatology. 33: 374-382. PMID 23047422 DOI: 10.1038/Jp.2012.124  0.347
2013 Yang M, Loberg A, Rizvi T, Wourms M, Song L, Burke K, Ratner N, Carmeliet P, LeCras T, Wills-Karp M, Malik P. Airway Hyper-Responsiveness Associated With Sickle Cell Disease Is Mediated By Placenta Growth Factor Blood. 122: 185-185. DOI: 10.1182/Blood.V122.21.185.185  0.405
2012 Wills-Karp M, Rani R, Dienger K, Lewkowich I, Fox JG, Perkins C, Lewis L, Finkelman FD, Smith DE, Bryce PJ, Kurt-Jones EA, Wang TC, Sivaprasad U, Hershey GK, Herbert DR. Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection. The Journal of Experimental Medicine. 209: 607-22. PMID 22329990 DOI: 10.1084/Jem.20110079  0.477
2011 Wills-Karp M, Finkelman FD. Innate lymphoid cells wield a double-edged sword. Nature Immunology. 12: 1025-7. PMID 22012433 DOI: 10.1038/Ni.2142  0.304
2011 Lewkowich IP, Day SB, Ledford JR, Zhou P, Dienger K, Wills-Karp M, Page K. Protease-activated receptor 2 activation of myeloid dendritic cells regulates allergic airway inflammation. Respiratory Research. 12: 122. PMID 21936897 DOI: 10.1186/1465-9921-12-122  0.372
2011 Wang YH, Wills-Karp M. The potential role of interleukin-17 in severe asthma. Current Allergy and Asthma Reports. 11: 388-94. PMID 21773747 DOI: 10.1007/S11882-011-0210-Y  0.528
2011 Schauberger EM, Ewart SL, Arshad SH, Huebner M, Karmaus W, Holloway JW, Friderici KH, Ziegler JT, Zhang H, Rose-Zerilli MJ, Barton SJ, Holgate ST, Kilpatrick JR, Harley JB, Lajoie-Kadoch S, ... ... Wills-Karp M, et al. Identification of ATPAF1 as a novel candidate gene for asthma in children. The Journal of Allergy and Clinical Immunology. 128: 753-760.e11. PMID 21696813 DOI: 10.1016/J.Jaci.2011.04.058  0.356
2011 Mohammed JP, Fusakio ME, Rainbow DB, Moule C, Fraser HI, Clark J, Todd JA, Peterson LB, Savage PB, Wills-Karp M, Ridgway WM, Wicker LS, Mattner J. Identification of Cd101 as a susceptibility gene for Novosphingobium aromaticivorans-induced liver autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 187: 337-49. PMID 21613619 DOI: 10.4049/Jimmunol.1003525  0.374
2011 Schroer KT, Gibson AM, Sivaprasad U, Bass SA, Ericksen MB, Wills-Karp M, Lecras T, Fitzpatrick AM, Brown LA, Stringer KF, Hershey GK. Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress. The Journal of Allergy and Clinical Immunology. 128: 539-48. PMID 21570714 DOI: 10.1016/J.Jaci.2011.04.018  0.389
2011 Perkins C, Yanase N, Smulian G, Gildea L, Orekov T, Potter C, Brombacher F, Aronow B, Wills-Karp M, Finkelman FD. Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice. The Journal of Experimental Medicine. 208: 853-67. PMID 21464224 DOI: 10.1084/Jem.20100023  0.466
2011 McCormack MC, Breysse PN, Matsui EC, Hansel NN, Peng RD, Curtin-Brosnan J, Williams DL, Wills-Karp M, Diette GB. Indoor particulate matter increases asthma morbidity in children with non-atopic and atopic asthma. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. 106: 308-15. PMID 21457879 DOI: 10.1016/J.Anai.2011.01.015  0.375
2011 Baye TM, Butsch Kovacic M, Biagini Myers JM, Martin LJ, Lindsey M, Patterson TL, He H, Ericksen MB, Gupta J, Tsoras AM, Lindsley A, Rothenberg ME, Wills-Karp M, Eissa NT, Borish L, et al. Differences in candidate gene association between European ancestry and African American asthmatic children. Plos One. 6: e16522. PMID 21387019 DOI: 10.1371/Journal.Pone.0016522  0.407
2011 Sivaprasad U, Askew DJ, Ericksen MB, Gibson AM, Stier MT, Brandt EB, Bass SA, Daines MO, Chakir J, Stringer KF, Wert SE, Whitsett JA, Le Cras TD, Wills-Karp M, Silverman GA, et al. A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma. The Journal of Allergy and Clinical Immunology. 127: 254-61, 261.e1-6. PMID 21126757 DOI: 10.1016/J.Jaci.2010.10.009  0.42
2011 Lajoie S, Lewkowich I, Wills-Karp M. IL-17A Increases Lung Myeloid DC Function In Experimental Allergic Asthma Journal of Allergy and Clinical Immunology. 127: AB165-AB165. DOI: 10.1016/J.Jaci.2010.12.656  0.448
2011 Burgess S, Wills-Karp M. Segmented Filamentous Bacteria Exacerbate Experimental Murine Asthma The Journal of Allergy and Clinical Immunology. 127. DOI: 10.1016/J.Jaci.2010.12.654  0.383
2011 Gour N, Dienger K, Wills-Karp M. Carbohydrate Moieties Contained in Dust Mite Allergen Promote IL-10 Production by Dendritic Cells The Journal of Allergy and Clinical Immunology. 127. DOI: 10.1016/J.Jaci.2010.12.645  0.39
2011 Buckingham C, Wills-Karp M. IL-17A Exacerbates Airway Hyperresponsiveness by Suppressing T regulatory Cell-Mediated Protection Journal of Allergy and Clinical Immunology. 127: AB125-AB125. DOI: 10.1016/J.Jaci.2010.12.498  0.431
2011 Lewkowich I, Wills-Karp M. IL-17A Directly Enhances IL-13-driven Stat6 Phosphorylation Journal of Allergy and Clinical Immunology. 127: AB124-AB124. DOI: 10.1016/J.Jaci.2010.12.497  0.359
2010 Wills-Karp M. Allergen-specific pattern recognition receptor pathways. Current Opinion in Immunology. 22: 777-82. PMID 21093238 DOI: 10.1016/J.Coi.2010.10.011  0.362
2010 Wills-Karp M, Kapsenberg M. Allergy and hypersensitivity. Current Opinion in Immunology. 22: 775-6. PMID 21071193 DOI: 10.1016/J.Coi.2010.10.017  0.308
2010 Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, König P, Gerard NP, Gerard C, Wills-Karp M, Köhl J. A critical role for C5L2 in the pathogenesis of experimental allergic asthma. Journal of Immunology (Baltimore, Md. : 1950). 185: 6741-52. PMID 20974988 DOI: 10.4049/Jimmunol.1000892  0.513
2010 Lajoie S, Lewkowich IP, Suzuki Y, Clark JR, Sproles AA, Dienger K, Budelsky AL, Wills-Karp M. Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma. Nature Immunology. 11: 928-35. PMID 20802484 DOI: 10.1038/Ni.1926  0.475
2010 Page K, Ledford JR, Zhou P, Dienger K, Wills-Karp M. Mucosal sensitization to German cockroach involves protease-activated receptor-2. Respiratory Research. 11: 62. PMID 20497568 DOI: 10.1186/1465-9921-11-62  0.39
2010 Chen G, Wan H, Luo F, Zhang L, Xu Y, Lewkowich I, Wills-Karp M, Whitsett JA. Foxa2 programs Th2 cell-mediated innate immunity in the developing lung. Journal of Immunology (Baltimore, Md. : 1950). 184: 6133-41. PMID 20483781 DOI: 10.4049/Jimmunol.1000223  0.469
2010 Finkelman FD, Hogan SP, Hershey GK, Rothenberg ME, Wills-Karp M. Importance of cytokines in murine allergic airway disease and human asthma. Journal of Immunology (Baltimore, Md. : 1950). 184: 1663-74. PMID 20130218 DOI: 10.4049/Jimmunol.0902185  0.525
2010 Saunders V, Breysse P, Clark J, Sproles A, Davila M, Wills-Karp M. Particulate matter-induced airway hyperresponsiveness is lymphocyte dependent. Environmental Health Perspectives. 118: 640-6. PMID 20061214 DOI: 10.1289/Ehp.0901461  0.428
2010 Wills-Karp M, Nathan A, Page K, Karp CL. New insights into innate immune mechanisms underlying allergenicity Mucosal Immunology. 3: 104-110. PMID 20032970 DOI: 10.1038/Mi.2009.138  0.343
2009 Page K, Ledford JR, Zhou P, Wills-Karp M. A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice. Journal of Immunology (Baltimore, Md. : 1950). 183: 3400-8. PMID 19667087 DOI: 10.4049/Jimmunol.0900838  0.42
2009 Niese KA, Collier AR, Hajek AR, Cederbaum SD, O'Brien WE, Wills-Karp M, Rothenberg ME, Zimmermann N. Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice. Bmc Immunology. 10: 33. PMID 19486531 DOI: 10.1186/1471-2172-10-33  0.449
2009 Zhang X, Lewkowich IP, Köhl G, Clark JR, Wills-Karp M, Köhl J. A protective role for C5a in the development of allergic asthma associated with altered levels of B7-H1 and B7-DC on plasmacytoid dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 5123-30. PMID 19342693 DOI: 10.4049/Jimmunol.0804276  0.42
2009 Lewis CC, Aronow B, Hutton J, Santeliz J, Dienger K, Herman N, Finkelman FD, Wills-Karp M. Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung. The Journal of Allergy and Clinical Immunology. 123: 795-804.e8. PMID 19249085 DOI: 10.1016/J.Jaci.2009.01.003  0.497
2009 Gu Y, Harley IT, Henderson LB, Aronow BJ, Vietor I, Huber LA, Harley JB, Kilpatrick JR, Langefeld CD, Williams AH, Jegga AG, Chen J, Wills-Karp M, Arshad SH, Ewart SL, et al. Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease. Nature. 458: 1039-42. PMID 19242412 DOI: 10.1038/Nature07811  0.343
2009 Nathan AT, Peterson EA, Chakir J, Wills-Karp M. Innate immune responses of airway epithelium to house dust mite are mediated through beta-glucan-dependent pathways. The Journal of Allergy and Clinical Immunology. 123: 612-8. PMID 19178937 DOI: 10.1016/J.Jaci.2008.12.006  0.439
2009 Trompette A, Divanovic S, Visintin A, Blanchard C, Hegde RS, Madan R, Thorne PS, Wills-Karp M, Gioannini TL, Weiss JP, Karp CL. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature. 457: 585-8. PMID 19060881 DOI: 10.1038/Nature07548  0.343
2009 Inoue Y, Dienger K, Clark J, Sproles A, Wills-Karp M. Mammalian Chitinase Family Members Inhibit House Dust Mite-induced Airway Hyperresponsiveness Regardless of These Enzymatic Activity Journal of Allergy and Clinical Immunology. 123: S258-S258. DOI: 10.1016/J.Jaci.2008.12.999  0.303
2009 Saunders V, Dienger K, Breysse P, Wills-Karp M. Ambient Particulate Matter-Induced CCL20 Production in Airway Epithelial Cells is NADPH Oxidase-Dependent Journal of Allergy and Clinical Immunology. 123: S173-S173. DOI: 10.1016/J.Jaci.2008.12.652  0.349
2008 Wills-Karp M, Finkelman FD. Untangling the complex web of IL-4- and IL-13-mediated signaling pathways. Science Signaling. 1: pe55. PMID 19109238 DOI: 10.1126/Scisignal.1.51.Pe55  0.392
2008 Lewkowich IP, Lajoie S, Clark JR, Herman NS, Sproles AA, Wills-Karp M. Allergen uptake, activation, and IL-23 production by pulmonary myeloid DCs drives airway hyperresponsiveness in asthma-susceptible mice. Plos One. 3: e3879. PMID 19060952 DOI: 10.1371/Journal.Pone.0003879  0.523
2008 Chen W, Tabata Y, Gibson AM, Daines MO, Warrier MR, Wills-Karp M, Hershey GK. Matrix metalloproteinase 8 contributes to solubilization of IL-13 receptor alpha2 in vivo. The Journal of Allergy and Clinical Immunology. 122: 625-32. PMID 18694590 DOI: 10.1016/J.Jaci.2008.06.022  0.38
2008 Page K, Lierl KM, Hughes VS, Zhou P, Ledford JR, Wills-Karp M. TLR2-mediated activation of neutrophils in response to German cockroach frass. Journal of Immunology (Baltimore, Md. : 1950). 180: 6317-24. PMID 18424755 DOI: 10.4049/Jimmunol.180.9.6317  0.416
2008 Finkelman FD, Wills-Karp M. Usefulness and optimization of mouse models of allergic airway disease. The Journal of Allergy and Clinical Immunology. 121: 603-6. PMID 18328889 DOI: 10.1016/J.Jaci.2008.01.008  0.392
2008 Zhang X, Köhl G, Clark J, Wills-Karp M, Köhl J. Distinct roles of C3aR, C5aR and C5L2 in the development of experimental allergic asthma Molecular Immunology. 45: 4152. DOI: 10.1016/J.Molimm.2008.08.169  0.415
2008 Lewis CC, Dienger K, Sproles A, Wills-Karp M. Altered Airway Epithelial Cell Phenotype is Associated with Susceptibility to Allergic Asthma The Journal of Allergy and Clinical Immunology. 121. DOI: 10.1016/J.Jaci.2007.12.810  0.445
2007 Page K, Lierl KM, Herman N, Wills-Karp M. Differences in susceptibility to German cockroach frass and its associated proteases in induced allergic inflammation in mice. Respiratory Research. 8: 91. PMID 18067672 DOI: 10.1186/1465-9921-8-91  0.453
2007 Khodoun M, Lewis CC, Lewis C, Yang JQ, Orekov T, Potter C, Wynn T, Mentink-Kane M, Hershey GK, Wills-Karp M, Finkelman FD. Differences in expression, affinity, and function of soluble (s)IL-4Ralpha and sIL-13Ralpha2 suggest opposite effects on allergic responses. Journal of Immunology (Baltimore, Md. : 1950). 179: 6429-38. PMID 17982031 DOI: 10.4049/Jimmunol.179.10.6429  0.402
2007 Wills-Karp M. Complement activation pathways: a bridge between innate and adaptive immune responses in asthma. Proceedings of the American Thoracic Society. 4: 247-51. PMID 17607007 DOI: 10.1513/pats.200704-046AW  0.316
2007 Köhl J, Wills-Karp M. A dual role for complement in allergic asthma. Current Opinion in Pharmacology. 7: 283-9. PMID 17475559 DOI: 10.1016/J.Coph.2007.01.005  0.455
2007 Abdala-Valencia H, Earwood J, Bansal S, Jansen M, Babcock G, Garvy B, Wills-Karp M, Cook-Mills JM. Nonhematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyperresponsiveness in experimentally induced asthma. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L1111-25. PMID 17293377 DOI: 10.1152/Ajplung.00208.2006  0.5
2007 Köhl J, Wills-Karp M. Complement regulates inhalation tolerance at the dendritic cell/T cell interface. Molecular Immunology. 44: 44-56. PMID 16889830 DOI: 10.1016/J.Molimm.2006.06.016  0.451
2007 Zhang X, Clark J, Köhl G, Wills-Karp M, Köhl J. Opposing roles for C5aR- and C3aR signaling in the development of maladaptive immunity in allergic asthma Molecular Immunology. 44: 3912. DOI: 10.1016/J.Molimm.2007.06.014  0.414
2007 Zhang X, Lewkowich IP, Baelder R, Wills-Karp M, Köhl J. C5a regulates B7 costimulatory molecule expression on distinct pulmonary dendritic cells to protect from type 2 immunity in asthma Molecular Immunology. 44: 264. DOI: 10.1016/J.Molimm.2006.07.275  0.376
2007 Grigoryev DN, Hoffman EP, Wills-Karp M, Barnes KC. Identification of Allergen-Susceptibility Genes Using Recombinant Inbred Mouse Model of Allergic Asthma The Journal of Allergy and Clinical Immunology. 119. DOI: 10.1016/J.Jaci.2006.12.536  0.391
2006 Ramadas RA, Li X, Shubitowski DM, Samineni S, Wills-Karp M, Ewart SL. IL-1 Receptor antagonist as a positional candidate gene in a murine model of allergic asthma. Immunogenetics. 58: 851-5. PMID 17021861 DOI: 10.1007/S00251-006-0146-X  0.481
2006 Li X, Wills-Karp M, Ewart S. Investigating Gata3 as a positional candidate gene for allergic asthma in a murine model International Journal of Immunogenetics. 33: 333-337. PMID 16984276 DOI: 10.1111/J.1744-313X.2006.00621.X  0.433
2006 Perkins C, Wills-Karp M, Finkelman FD. IL-4 induces IL-13-independent allergic airway inflammation. The Journal of Allergy and Clinical Immunology. 118: 410-9. PMID 16890766 DOI: 10.1016/J.Jaci.2006.06.004  0.436
2006 Barnes KC, Grant A, Gao P, Baltadjieva D, Berg T, Chi P, Zhang S, Zambelli-Weiner A, Ehrlich E, Zardkoohi O, Brummet ME, Stockton M, Watkins T, Gao L, Gittens M, ... Wills-Karp M, et al. Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes Journal of Allergy and Clinical Immunology. 118: 70-77. PMID 16815140 DOI: 10.1016/J.Jaci.2006.03.036  0.396
2006 Goebel J, Forrest K, Wills-Karp M, Roszman TL. Tubulin polymerization modulates interleukin-2 receptor signal transduction in human T cells. Journal of Receptor and Signal Transduction Research. 26: 87-106. PMID 16595340 DOI: 10.1080/10799890600567372  0.394
2006 Köhl J, Baelder R, Lewkowich IP, Pandey MK, Hawlisch H, Wang L, Best J, Herman NS, Sproles AA, Zwirner J, Whitsett JA, Gerard C, Sfyroera G, Lambris JD, Wills-Karp M. A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma. The Journal of Clinical Investigation. 116: 783-96. PMID 16511606 DOI: 10.1172/Jci26582  0.489
2006 Keen JC, Cianferoni A, Florio G, Guo J, Chen R, Roman J, Wills-Karp M, Casolaro V, Georas SN. Characterization of a novel PMA-inducible pathway of interleukin-13 gene expression in T cells. Immunology. 117: 29-37. PMID 16423038 DOI: 10.1111/J.1365-2567.2005.02260.X  0.723
2006 Follettie MT, Ellis DK, Donaldson DD, Hill AA, Diesl V, DeClercq C, Sypek JP, Dorner AJ, Wills-Karp M. Gene expression analysis in a murine model of allergic asthma reveals overlapping disease and therapy dependent pathways in the lung. The Pharmacogenomics Journal. 6: 141-52. PMID 16402082 DOI: 10.1038/Sj.Tpj.6500357  0.505
2006 Molloy CA, Morrow AL, Meinzen-Derr J, Schleifer K, Dienger K, Manning-Courtney P, Altaye M, Wills-Karp M. Elevated cytokine levels in children with autism spectrum disorder. Journal of Neuroimmunology. 172: 198-205. PMID 16360218 DOI: 10.1016/J.Jneuroim.2005.11.007  0.38
2006 Barnes KC, Grant AV, Baltadzhieva D, Zhang S, Berg T, Shao L, Zambelli-Weiner A, Anderson W, Nelsen A, Pillai S, Yarnall DP, Dienger K, Ingersoll RG, Scott AF, Fallin MD, ... ... Wills-Karp M, et al. Variants in the gene encoding C3 are associated with asthma and related phenotypes among African Caribbean families. Genes and Immunity. 7: 27-35. PMID 16355111 DOI: 10.1038/Sj.Gene.6364267  0.394
2006 Lewkowich I, Herman N, Schleifer K, Sproles A, Wills-Karp M. Regulatory T Cells Protect Against Experimentally-Induced Asthma by Altering the Dendritic Cell Phenotype and Activation State Journal of Allergy and Clinical Immunology. 117: S243. DOI: 10.1016/J.Jaci.2005.12.964  0.4
2005 Lewkowich IP, Herman NS, Schleifer KW, Dance MP, Chen BL, Dienger KM, Sproles AA, Shah JS, Köhl J, Belkaid Y, Wills-Karp M. CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function. The Journal of Experimental Medicine. 202: 1549-61. PMID 16314437 DOI: 10.1084/Jem.20051506  0.4
2005 Hessel EM, Chu M, Lizcano JO, Chang B, Herman N, Kell SA, Wills-Karp M, Coffman RL. Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction. The Journal of Experimental Medicine. 202: 1563-73. PMID 16314434 DOI: 10.1084/Jem.20050631  0.457
2005 Goebel J, Logan B, Forrest K, Mieczkowski A, Roszman TL, Wills-Karp M. Atorvastatin affects interleukin-2 signaling by altering the lipid raft enrichment of the interleukin-2 receptor beta chain. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 53: 322-8. PMID 16207471 DOI: 10.2310/6650.2005.53610  0.352
2005 Wills-Karp M, Koehl J. New insights into the role of the complement pathway in allergy and asthma. Current Allergy and Asthma Reports. 5: 362-9. PMID 16091207 DOI: 10.1007/S11882-005-0007-Y  0.434
2005 Finkelman FD, Yang M, Perkins C, Schleifer K, Sproles A, Santeliz J, Bernstein JA, Rothenberg ME, Morris SC, Wills-Karp M. Suppressive effect of IL-4 on IL-13-induced genes in mouse lung. Journal of Immunology (Baltimore, Md. : 1950). 174: 4630-8. PMID 15814686 DOI: 10.4049/Jimmunol.174.8.4630  0.428
2005 Zimmermann N, Doepker MP, Witte DP, Stringer KF, Fulkerson PC, Pope SM, Brandt EB, Mishra A, King NE, Nikolaidis NM, Wills-Karp M, Finkelman FD, Rothenberg ME. Expression and regulation of small proline-rich protein 2 in allergic inflammation. American Journal of Respiratory Cell and Molecular Biology. 32: 428-35. PMID 15731505 DOI: 10.1165/Rcmb.2004-0269Oc  0.538
2005 Guajardo JR, Schleifer KW, Daines MO, Ruddy RM, Aronow BJ, Wills-Karp M, Hershey GK. Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma. The Journal of Allergy and Clinical Immunology. 115: 243-51. PMID 15696077 DOI: 10.1016/J.Jaci.2004.10.032  0.405
2004 Wills-Karp M. Interleukin-13 in asthma pathogenesis. Immunological Reviews. 202: 175-90. PMID 15546393 DOI: 10.1111/J.0105-2896.2004.00215.X  0.509
2004 Wills-Karp M, Karp CL. Chitin checking--novel insights into asthma. The New England Journal of Medicine. 351: 1455-7. PMID 15459309 DOI: 10.1056/Nejmcibr041294  0.452
2004 Wills-Karp M, Brandt D, Morrow AL. Understanding the origin of asthma and its relationship to breastfeeding. Advances in Experimental Medicine and Biology. 554: 171-91. PMID 15384576 DOI: 10.1007/978-1-4757-4242-8_16  0.418
2004 Wills-Karp M, Karp CL. Biomedicine. Eosinophils in asthma: remodeling a tangled tale. Science (New York, N.Y.). 305: 1726-9. PMID 15375256 DOI: 10.1126/Science.1104134  0.404
2004 Hawlisch H, Wills-Karp M, Karp CL, Köhl J. The anaphylatoxins bridge innate and adaptive immune responses in allergic asthma. Molecular Immunology. 41: 123-31. PMID 15159057 DOI: 10.1016/J.Molimm.2004.03.019  0.349
2004 Barnes KC, Caraballo L, Muñoz M, Zambelli-Weiner A, Ehrlich E, Burki M, Jimenez S, Mathias RA, Stockton ML, Deindl P, Mendoza L, Hershey GK, Nickel R, Wills-Karp M. A novel promoter polymorphism in the gene encoding complement component 5 receptor 1 on chromosome 19q13.3 is not associated with asthma and atopy in three independent populations. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 34: 736-44. PMID 15144465 DOI: 10.1111/J.1365-2222.2004.1942.X  0.376
2004 Wills-Karp M, Ewart SL. Time to draw breath: asthma-susceptibility genes are identified. Nature Reviews. Genetics. 5: 376-87. PMID 15143320 DOI: 10.1038/Nrg1326  0.381
2004 Karp CL, Flick LM, Park KW, Softic S, Greer TM, Keledjian R, Yang R, Uddin J, Guggino WB, Atabani SF, Belkaid Y, Xu Y, Whitsett JA, Accurso FJ, Wills-Karp M, et al. Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway. Nature Immunology. 5: 388-92. PMID 15034576 DOI: 10.1038/Ni1056  0.351
2004 Wills-Karp M. Interleukin-13 in asthma pathogenesis. Current Allergy and Asthma Reports. 4: 123-31. PMID 14769261  0.405
2003 Wills-Karp M, Belkaid Y, Karp CL. I-Tim-izing the pathways of counter-regulation. Nature Immunology. 4: 1050-2. PMID 14586421 DOI: 10.1038/Ni1103-1050  0.317
2003 Wills-Karp M, Chiaramonte M. Interleukin-13 in asthma. Current Opinion in Pulmonary Medicine. 9: 21-7. PMID 12476080 DOI: 10.1097/00063198-200301000-00004  0.497
2003 Munoz M, Zambelli-Weiner A, Ehrlich E, Jimenez S, Caraballo L, Wills-Karp M, Barnes KC. A novel single nucleotide polymorphism in complement component 5 receptor 1 (C5aR) on chromosome 19q13.3 is not associated with asthma in an Afro-Caribbean population The Journal of Allergy and Clinical Immunology. 111. DOI: 10.1016/S0091-6749(03)81140-5  0.312
2002 Shubitowski DM, Wills-Karp M, Ewart SL. The complement factor 5a receptor gene maps to murine chromosome 7 Cytogenetic and Genome Research. 97: 133-135. PMID 12438752 DOI: 10.1159/000064054  0.347
2002 Walters DM, Breysse PN, Schofield B, Wills-Karp M. Complement factor 3 mediates particulate matter-induced airway hyperresponsiveness. American Journal of Respiratory Cell and Molecular Biology. 27: 413-8. PMID 12356574 DOI: 10.1165/Rcmb.4844  0.643
2002 Santeliz JV, Van Nest G, Traquina P, Larsen E, Wills-Karp M. Amb a 1-linked CpG oligodeoxynucleotides reverse established airway hyperresponsiveness in a murine model of asthma. The Journal of Allergy and Clinical Immunology. 109: 455-62. PMID 11897991 DOI: 10.1067/Mai.2002.122156  0.414
2001 Wills-Karp M, Santeliz J, Karp CL. The germless theory of allergic disease: Revisiting the hygiene hypothesis Nature Reviews Immunology. 1: 69-75. PMID 11905816 DOI: 10.1038/35095579  0.311
2001 Wills-Karp M. Asthma genetics: Not for the TIMid? Nature Immunology. 2: 1095-1096. PMID 11725296 DOI: 10.1038/Ni1201-1095  0.416
2001 Walters DM, Breysse PN, Wills-Karp M. Ambient urban Baltimore particulate-induced airway hyperresponsiveness and inflammation in mice. American Journal of Respiratory and Critical Care Medicine. 164: 1438-43. PMID 11704592 DOI: 10.1164/Ajrccm.164.8.2007121  0.668
2001 Chen ES, Greenlee BM, Wills-Karp M, Moller DR. Attenuation of lung inflammation and fibrosis in interferon-γ-deficient mice after intratracheal bleomycin American Journal of Respiratory Cell and Molecular Biology. 24: 545-555. PMID 11350823 DOI: 10.1165/Ajrcmb.24.5.4064  0.378
2001 Karp CL, Wills-Karp M. Complement and IL-12: Yin and yang Microbes and Infection. 3: 109-119. PMID 11251297 DOI: 10.1016/S1286-4579(00)01358-7  0.443
2001 Keen JC, Sholl L, Wills-Karp M, Georas SN. Preferential activation of nuclear factor of activated T cells c correlates with mouse strain susceptibility to allergic responses and interleukin-4 gene expression. American Journal of Respiratory Cell and Molecular Biology. 24: 58-65. PMID 11152651 DOI: 10.1165/Ajrcmb.24.1.3870  0.743
2001 Wills-Karp M. IL-12/IL-13 axis in allergic asthma Journal of Allergy and Clinical Immunology. 107: 9-18. PMID 11149983 DOI: 10.1067/Mai.2001.112265  0.502
2001 Chen ES, Greenlee BM, Wills-Karp M, Moller DR. Bleomycin-induced pulmonary fibrosis is attenuated in interferon-γ knockout mice Chest. 120. DOI: 10.1016/S0012-3692(15)38672-4  0.31
2000 Wills-Karp M. The gene encoding interleukin-13: A susceptibility locus for asthma and related traits Respiratory Research. 1: 19-23. PMID 11667960 DOI: 10.1186/Rr7  0.443
2000 Ewart SL, Kuperman D, Schadt E, Tankersley C, Grupe A, Shubitowski DM, Peltz G, Wills-Karp M. Quantitative trait loci controlling allergen-induced airway hyperresponsiveness in inbred mice American Journal of Respiratory Cell and Molecular Biology. 23: 537-545. PMID 11017920 DOI: 10.1165/Ajrcmb.23.4.4199  0.429
2000 Walters DM, Wills-Karp M, Mitzner W. Assessment of cellular profile and lung function with repeated bronchoalveolar lavage in individual mice. Physiological Genomics. 2: 29-36. PMID 11015579 DOI: 10.1152/Physiolgenomics.2000.2.1.29  0.609
2000 Karp CL, Grupe A, Schadt E, Ewart SL, Keane-Moore M, Cuomo PJ, Köhl J, Wahl L, Kuperman D, Germer S, Aud D, Peltz G, Wills-Karp M. Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma. Nature Immunology. 1: 221-6. PMID 10973279 DOI: 10.1038/79759  0.512
2000 Wills-Karp M. Murine models of asthma in understanding immune dysregulation in human asthma Immunopharmacology. 48: 263-268. PMID 10960667 DOI: 10.1016/S0162-3109(00)00223-X  0.532
2000 Wills-Karp M. Trophic slime, allergic slime American Journal of Respiratory Cell and Molecular Biology. 22: 637-639. PMID 10837356 DOI: 10.1165/Ajrcmb.22.6.F190  0.464
2000 Walters DM, Wills-Karp M, Mitzner W. Assessment of cellular profile lung function with repeated bronchoalveolar lavage in individual mice Physiological Genomics. 2000: 29-36.  0.575
1999 Mayer RJ, Wills-Karp M. Recent insights into pathogenesis and control of asthma and atopic diseases. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 48: 469-70. PMID 10651515 DOI: 10.1007/S000110050488  0.393
1999 Wills-Karp M. Immunologic basis of antigen-induced airway hyperresponsiveness Annual Review of Immunology. 17: 255-281. PMID 10358759 DOI: 10.1146/Annurev.Immunol.17.1.255  0.522
1999 Eggleston PA, Buckley TJ, Breysse PN, Wills-Karp M, Kleeberger SR, Jaakkola JJK. The environment and asthma in U.S. inner cities Environmental Health Perspectives. 107: 439-450. PMID 10346992 DOI: 10.1289/Ehp.99107S3439  0.4
1999 Wills-Karp M, Luyimbazi J, Xu X, Schofield B, Neben TY, Karp CL, Donaldson DD. Interleukin-13: Central mediator of allergic asthma Pneumologie. 53. DOI: 10.1126/Science.282.5397.2258  0.517
1998 Keane-Myers A, Wysocka M, Trinchieri G, Wills-Karp M. Resistance to antigen-induced airway hyperresponsiveness requires endogenous production of IL-12 Journal of Immunology. 161: 919-926. PMID 9670970  0.374
1998 Keane-Myers AM, Gause WC, Finkelman FD, Xhou XD, Wills-Karp M. Development of murine allergic asthma is dependent upon B7-2 costimulation Journal of Immunology. 160: 1036-1043. PMID 9551945  0.427
1998 Wills-Karp M. Interleukin-12 as a target for modulation of the inflammatory response in asthma Allergy: European Journal of Allergy and Clinical Immunology. 53: 113-119. PMID 9534908 DOI: 10.1111/J.1398-9995.1998.Tb03858.X  0.407
1998 Kuperman D, Schofield B, Wills-Karp M, Grusby MJ. Signal transducer and activator of transcription factor 6 (Stat6)- deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production Journal of Experimental Medicine. 187: 939-948. PMID 9500796 DOI: 10.1084/Jem.187.6.939  0.48
1997 Wills-Karp M, Ewart SL. The genetics of allergen-induced airway hyperresponsiveness in mice American Journal of Respiratory and Critical Care Medicine. 156. PMID 9351586 DOI: 10.1164/Ajrccm.156.4.12-Tac-3  0.521
1997 Gavett SH, O'Hearn DJ, Karp CL, Patel EA, Schofield BH, Finkelman FD, Wills-Karp M. Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice American Journal of Physiology - Lung Cellular and Molecular Physiology. 272. PMID 9124376 DOI: 10.1152/Ajplung.1997.272.2.L253  0.456
1996 Wills-Karp M, Gavett SH, Schofield B, Finkelman F. Role of interleukin-4 in the development of allergic airway inflammation and airway hyperresponsiveness Advances in Experimental Medicine and Biology. 409: 343-347. PMID 9095263 DOI: 10.1007/978-1-4615-5855-2_48  0.489
1996 Li XM, Chopra RK, Chou TY, Schofield BH, Wills-Karp M, Huang SK. Mucosal IFN-γ Gene Transfer Inhibits Pulmonary Allergic Responses in Mice Journal of Immunology. 157: 3216-3219. PMID 8871613  0.329
1996 Ewart SL, Gavett SH, Margolick J, Wills-Karp M. Cyclosporin A Attenuates Genetic Airway Hyperresponsiveness in Mice but Not through Inhibition of CD4+ or CD8+ T Cells American Journal of Respiratory Cell and Molecular Biology. 14: 627-634. PMID 8652191 DOI: 10.1165/Ajrcmb.14.6.8652191  0.353
1995 Chen X, Gavett SH, Wills-Karp M. CD4+ T lymphocyte modulation of ozone-induced murine pulmonary inflammation American Journal of Respiratory Cell and Molecular Biology. 12: 396-403. PMID 7695918 DOI: 10.1165/Ajrcmb.12.4.7695918  0.413
1995 Gavett SH, O'Hearn DJ, Li X, Huang SK, Finkelman FD, Wills-Karp M. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice Journal of Experimental Medicine. 182: 1527-1536. PMID 7595222 DOI: 10.1084/Jem.182.5.1527  0.505
1994 Gavett SH, Chen X, Finkelman F, Wills-Karp M. Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia American Journal of Respiratory Cell and Molecular Biology. 10: 587-593. PMID 8003337 DOI: 10.1165/Ajrcmb.10.6.8003337  0.405
1993 Wills-Karp M, Uchida Y, Lee JY, Jinot J, Hirata A, Hirata F. Organ culture with proinflammatory cytokines reproduces impairment of the beta-adrenoceptor-mediated relaxation in tracheas of a guinea pig antigen model American Journal of Respiratory Cell and Molecular Biology. 8: 153-159. PMID 8381292 DOI: 10.1165/Ajrcmb/8.2.153  0.391
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