Charles J. Lowenstein - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Immunology, Microbiology Biology

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Bennett JA, Ture SK, Schmidt RA, Mastrangelo MA, Cameron SJ, Terry LE, Yule DI, Morrell CN, Lowenstein CJ. Acetylcholine inhibits platelet activation. The Journal of Pharmacology and Experimental Therapeutics. PMID 30765424 DOI: 10.1124/jpet.118.253583  0.48
2018 Sabater-Lleal M, Huffman JE, de Vries PS, Marten J, Mastrangelo MA, Song C, Pankratz N, Ward-Caviness CK, Yanek LR, Trompet S, Delgado GE, Guo X, Bartz TM, Martinez-Perez A, Germain M, ... ... Lowenstein CJ, et al. Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels. Circulation. PMID 30586737 DOI: 10.1161/CIRCULATIONAHA.118.034532  0.32
2018 Croft D, Block R, Cameron SJ, Evans K, Lowenstein CJ, Ling F, Zareba W, Hopke PK, Utell MJ, Thurston SW, Thevenet-Morrison K, Rich DQ. Do elevated blood levels of omega-3 fatty acids modify effects of particulate air pollutants on fibrinogen? Air Quality, Atmosphere, & Health. 11: 791-799. PMID 30147809 DOI: 10.1007/s11869-018-0586-0  0.44
2017 Croft DP, Cameron SJ, Morrell CN, Lowenstein CJ, Ling F, Zareba W, Hopke PK, Utell MJ, Thurston SW, Thevenet-Morrison K, Evans KA, Chalupa D, Rich DQ. Associations between ambient wood smoke and other particulate pollutants and biomarkers of systemic inflammation, coagulation and thrombosis in cardiac patients. Environmental Research. 154: 352-361. PMID 28167447 DOI: 10.1016/j.envres.2017.01.027  0.48
2016 Zhu QM, Ko KA, Ture S, Mastrangelo MA, Chen MH, Johnson AD, O'Donnell CJ, Morrell CN, Miano JM, Lowenstein CJ. Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28062498 DOI: 10.1161/ATVBAHA.116.308614  0.48
2016 Zhu QM, Yamakuchi M, Lowenstein CJ. Correction: SNAP23 Regulates Endothelial Exocytosis of von Willebrand Factor. Plos One. 11: e0147167. PMID 26752636 DOI: 10.1371/journal.pone.0147167  0.48
2015 Cameron SJ, Morrell CN, Bao C, Swaim AF, Rodriguez A, Lowenstein CJ. A Novel Anti-Inflammatory Effect for High Density Lipoprotein. Plos One. 10: e0144372. PMID 26680360 DOI: 10.1371/journal.pone.0144372  0.48
2015 Zhu Q, Yamakuchi M, Lowenstein CJ. SNAP23 Regulates Endothelial Exocytosis of von Willebrand Factor. Plos One. 10: e0118737. PMID 26266817 DOI: 10.1371/journal.pone.0118737  0.48
2014 Zhu Q, Yamakuchi M, Ture S, de la Luz Garcia-Hernandez M, Ko KA, Modjeski KL, LoMonaco MB, Johnson AD, O'Donnell CJ, Takai Y, Morrell CN, Lowenstein CJ. Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion. The Journal of Clinical Investigation. 124: 4503-16. PMID 25244095 DOI: 10.1172/JCI71245  0.48
2014 LoMonaco MB, Lowenstein CJ. Enhanced assay of endothelial exocytosis using extracellular matrix components. Analytical Biochemistry. 452: 19-24. PMID 24561025 DOI: 10.1016/j.ab.2014.02.015  0.48
2014 Jeong Y, Du R, Zhu X, Yin S, Wang J, Cui H, Cao W, Lowenstein CJ. Histone deacetylase isoforms regulate innate immune responses by deacetylating mitogen-activated protein kinase phosphatase-1. Journal of Leukocyte Biology. 95: 651-9. PMID 24374966 DOI: 10.1189/jlb.1013565  0.48
2011 Yamakuchi M, Yagi S, Ito T, Lowenstein CJ. MicroRNA-22 regulates hypoxia signaling in colon cancer cells. Plos One. 6: e20291. PMID 21629773 DOI: 10.1371/journal.pone.0020291  0.48
2011 Lowenstein CJ. Vav-Vav-Vav-voom! Blood. 117: 5557-9. PMID 21617008 DOI: 10.1182/blood-2011-04-345561  0.48
2011 Ito T, Yamakuchi M, Lowenstein CJ. Thioredoxin increases exocytosis by denitrosylating N-ethylmaleimide-sensitive factor. The Journal of Biological Chemistry. 286: 11179-84. PMID 21324905 DOI: 10.1074/jbc.M110.201780  0.48
2010 Ferlito M, Fulton WB, Zauher MA, Marbán E, Steenbergen C, Lowenstein CJ. VAMP-1, VAMP-2, and syntaxin-4 regulate ANP release from cardiac myocytes. Journal of Molecular and Cellular Cardiology. 49: 791-800. PMID 20801128 DOI: 10.1016/j.yjmcc.2010.08.020  0.48
2010 Harris TA, Yamakuchi M, Kondo M, Oettgen P, Lowenstein CJ. Ets-1 and Ets-2 regulate the expression of microRNA-126 in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1990-7. PMID 20671229 DOI: 10.1161/ATVBAHA.110.211706  0.48
2010 Goel A, Su B, Flavahan S, Lowenstein CJ, Berkowitz DE, Flavahan NA. Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries. Circulation Research. 107: 242-51. PMID 20522806 DOI: 10.1161/CIRCRESAHA.109.210229  0.48
2010 Bie B, Zhang Z, Cai YQ, Zhu W, Zhang Y, Dai J, Lowenstein CJ, Weinman EJ, Pan ZZ. Nerve growth factor-regulated emergence of functional delta-opioid receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5617-28. PMID 20410114 DOI: 10.1523/JNEUROSCI.5296-09.2010  0.48
2010 Yamakuchi M, Lotterman CD, Bao C, Hruban RH, Karim B, Mendell JT, Huso D, Lowenstein CJ. P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 6334-9. PMID 20308559 DOI: 10.1073/pnas.0911082107  0.48
2010 Lowenstein CJ, Cameron SJ. High-density lipoprotein metabolism and endothelial function. Current Opinion in Endocrinology, Diabetes, and Obesity. 17: 166-70. PMID 20125006 DOI: 10.1097/MED.0b013e32833727ee  0.44
2010 Tseng EE, Brock MV, Lange MS, Troncoso JC, Blue ME, Lowenstein CJ, Johnston MV, Baumgartner WA. Glutamate excitotoxicity mediates neuronal apoptosis after hypothermic circulatory arrest. The Annals of Thoracic Surgery. 89: 440-5. PMID 20103318 DOI: 10.1016/j.athoracsur.2009.10.059  0.48
2009 Jeong Y, Chaupin DF, Matsushita K, Yamakuchi M, Cameron SJ, Morrell CN, Lowenstein CJ. Aldosterone activates endothelial exocytosis. Proceedings of the National Academy of Sciences of the United States of America. 106: 3782-7. PMID 19223584 DOI: 10.1073/pnas.0804037106  0.48
2009 Yamakuchi M, Lowenstein CJ. MiR-34, SIRT1 and p53: the feedback loop. Cell Cycle (Georgetown, Tex.). 8: 712-5. PMID 19221490  0.48
2008 Yamakuchi M, Ferlito M, Lowenstein CJ. miR-34a repression of SIRT1 regulates apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 13421-6. PMID 18755897 DOI: 10.1073/pnas.0801613105  0.48
2008 Yamakuchi M, Bao C, Ferlito M, Lowenstein CJ. Epigallocatechin gallate inhibits endothelial exocytosis. Biological Chemistry. 389: 935-41. PMID 18627310 DOI: 10.1515/BC.2008.095  0.48
2008 Cao W, Bao C, Padalko E, Lowenstein CJ. Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling. The Journal of Experimental Medicine. 205: 1491-503. PMID 18504304 DOI: 10.1084/jem.20071728  0.48
2008 Yamakuchi M, Ferlito M, Morrell CN, Matsushita K, Fletcher CA, Cao W, Lowenstein CJ. Exocytosis of endothelial cells is regulated by N-ethylmaleimide-sensitive factor. Methods in Molecular Biology (Clifton, N.J.). 440: 203-15. PMID 18369947 DOI: 10.1007/978-1-59745-178-9_15  0.48
2008 Morrell CN, Sun H, Ikeda M, Beique JC, Swaim AM, Mason E, Martin TV, Thompson LE, Gozen O, Ampagoomian D, Sprengel R, Rothstein J, Faraday N, Huganir R, Lowenstein CJ. Glutamate mediates platelet activation through the AMPA receptor. The Journal of Experimental Medicine. 205: 575-84. PMID 18283118 DOI: 10.1084/jem.20071474  0.48
2008 Harris TA, Yamakuchi M, Ferlito M, Mendell JT, Lowenstein CJ. MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proceedings of the National Academy of Sciences of the United States of America. 105: 1516-21. PMID 18227515 DOI: 10.1073/pnas.0707493105  0.48
2008 Kanno Y, Into T, Lowenstein CJ, Matsushita K. Nitric oxide regulates vascular calcification by interfering with TGF- signalling. Cardiovascular Research. 77: 221-30. PMID 18006450 DOI: 10.1093/cvr/cvm049  0.48
2007 Lowenstein CJ. Myocardial reperfusion injury. The New England Journal of Medicine. 357: 2409; author reply 2. PMID 18069136  0.48
2007 Calvert JW, Gundewar S, Yamakuchi M, Park PC, Baldwin WM, Lefer DJ, Lowenstein CJ. Inhibition of N-ethylmaleimide-sensitive factor protects against myocardial ischemia/reperfusion injury. Circulation Research. 101: 1247-54. PMID 17932325 DOI: 10.1161/CIRCRESAHA.107.162610  0.48
2007 Johnston CP, Qiu H, Ticehurst JR, Dickson C, Rosenbaum P, Lawson P, Stokes AB, Lowenstein CJ, Kaminsky M, Cosgrove SE, Green KY, Perl TM. Outbreak management and implications of a nosocomial norovirus outbreak. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 45: 534-40. PMID 17682985 DOI: 10.1086/520666  0.48
2007 Lamas S, Lowenstein CJ, Michel T. Nitric oxide signaling comes of age: 20 years and thriving. Cardiovascular Research. 75: 207-9. PMID 17574221 DOI: 10.1016/j.cardiores.2007.05.023  0.48
2007 Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH, Feldmann G, Yamakuchi M, Ferlito M, Lowenstein CJ, Arking DE, Beer MA, Maitra A, Mendell JT. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Molecular Cell. 26: 745-52. PMID 17540599 DOI: 10.1016/j.molcel.2007.05.010  0.48
2007 Lowenstein CJ. Nitric oxide regulation of protein trafficking in the cardiovascular system. Cardiovascular Research. 75: 240-6. PMID 17490627 DOI: 10.1016/j.cardiores.2007.03.024  0.48
2007 Saura M, Lizarbe TR, Rama-Pacheco C, Lowenstein CJ, Zaragoza C. Inhibitor of NF kappa B alpha is a host sensor of coxsackievirus infection. Cell Cycle (Georgetown, Tex.). 6: 503-6. PMID 17351338  0.48
2007 Yamakuchi M, Kirkiles-Smith NC, Ferlito M, Cameron SJ, Bao C, Fox-Talbot K, Wasowska BA, Baldwin WM, Pober JS, Lowenstein CJ. Antibody to human leukocyte antigen triggers endothelial exocytosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 1301-6. PMID 17229850 DOI: 10.1073/pnas.0602035104  0.48
2007 Into T, Kanno Y, Dohkan J, Nakashima M, Inomata M, Shibata K, Lowenstein CJ, Matsushita K. Pathogen recognition by Toll-like receptor 2 activates Weibel-Palade body exocytosis in human aortic endothelial cells. The Journal of Biological Chemistry. 282: 8134-41. PMID 17227763 DOI: 10.1074/jbc.M609962200  0.48
2007 Lowenstein CJ, Morrell CN, Yamakuchi M. Weibel-palade bodies: Vesicular trafficking on the vascular highways Endothelial Biomedicine. 657-663. DOI: 10.1017/CBO9780511546198.073  0.48
2006 Zaragoza C, Saura M, Padalko EY, Lopez-Rivera E, Lizarbe TR, Lamas S, Lowenstein CJ. Viral protease cleavage of inhibitor of kappaBalpha triggers host cell apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 19051-6. PMID 17138672 DOI: 10.1073/pnas.0606019103  0.48
2006 Lowenstein CJ, Tsuda H. N-ethylmaleimide-sensitive factor: a redox sensor in exocytosis. Biological Chemistry. 387: 1377-83. PMID 17081110 DOI: 10.1515/BC.2006.173  0.48
2006 Lowenstein CJ. Integrin-linked kinase plays a key role in coxsackievirus replication. Circulation Research. 99: 346-7. PMID 16917101 DOI: 10.1161/01.RES.0000239428.01434.e2  0.48
2006 Saura M, Zaragoza C, Bao C, Herranz B, Rodriguez-Puyol M, Lowenstein CJ. Stat3 mediates interleukin-6 [correction of interelukin-6] inhibition of human endothelial nitric-oxide synthase expression. The Journal of Biological Chemistry. 281: 30057-62. PMID 16887796 DOI: 10.1074/jbc.M606279200  0.48
2006 Lowenstein CJ. Beneficial effects of neuronal nitric oxide synthase in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1417-8. PMID 16794230 DOI: 10.1161/01.ATV.0000226550.89264.91  0.48
2006 Ohnishi T, Kakimoto K, Bandow K, Lowenstein CJ, Daikuhara Y, Matsuguchi T. Mature hepatocyte growth factor/scatter factor on the surface of human granulocytes is released by a mechanism involving activated factor Xa. Journal of Immunology (Baltimore, Md. : 1950). 176: 6945-53. PMID 16709855  0.48
2005 Kittleson MM, Lowenstein CJ, Hare JM. Novel pathogenetic mechanisms in myocarditis: nitric oxide signaling. Heart Failure Clinics. 1: 345-61. PMID 17386859 DOI: 10.1016/j.hfc.2005.06.002  0.48
2005 Lowenstein CJ, Morrell CN, Yamakuchi M. Regulation of Weibel-Palade body exocytosis. Trends in Cardiovascular Medicine. 15: 302-8. PMID 16297768 DOI: 10.1016/j.tcm.2005.09.005  0.48
2005 Matsushita K, Morrell CN, Mason RJ, Yamakuchi M, Khanday FA, Irani K, Lowenstein CJ. Hydrogen peroxide regulation of endothelial exocytosis by inhibition of N-ethylmaleimide sensitive factor. The Journal of Cell Biology. 170: 73-9. PMID 15998800 DOI: 10.1083/jcb.200502031  0.48
2005 Yamakuchi M, Greer JJ, Cameron SJ, Matsushita K, Morrell CN, Talbot-Fox K, Baldwin WM, Lefer DJ, Lowenstein CJ. HMG-CoA reductase inhibitors inhibit endothelial exocytosis and decrease myocardial infarct size. Circulation Research. 96: 1185-92. PMID 15905463 DOI: 10.1161/01.RES.0000170229.49776.81  0.48
2005 Morrell CN, Matsushita K, Lowenstein CJ. A novel inhibitor of N-ethylmaleimide-sensitive factor decreases leukocyte trafficking and peritonitis. The Journal of Pharmacology and Experimental Therapeutics. 314: 155-61. PMID 15778265 DOI: 10.1124/jpet.104.082529  0.48
2005 Morrell CN, Matsushita K, Chiles K, Scharpf RB, Yamakuchi M, Mason RJ, Bergmeier W, Mankowski JL, Baldwin WM, Faraday N, Lowenstein CJ. Regulation of platelet granule exocytosis by S-nitrosylation. Proceedings of the National Academy of Sciences of the United States of America. 102: 3782-7. PMID 15738422 DOI: 10.1073/pnas.0408310102  0.48
2005 Matsushita K, Morrell CN, Lowenstein CJ. A novel class of fusion polypeptides inhibits exocytosis. Molecular Pharmacology. 67: 1137-44. PMID 15608145 DOI: 10.1124/mol.104.004275  0.48
2005 Matsushita K, Yamakuchi M, Morrell CN, Ozaki M, O'Rourke B, Irani K, Lowenstein CJ. Vascular endothelial growth factor regulation of Weibel-Palade-body exocytosis. Blood. 105: 207-14. PMID 15345585 DOI: 10.1182/blood-2004-04-1519  0.48
2005 Lowenstein CJ. Platelets trigger endothelial exocytosis Blood. 106: 2223. DOI: 10.1182/blood-2005-07-2825  0.48
2004 Yang SX, Yan J, Deshpande SS, Irani K, Lowenstein CJ. Rac1 regulates the release of Weibel-Palade Bodies in human aortic endothelial cells. Chinese Medical Journal. 117: 1143-50. PMID 15361285  0.48
2004 Lowenstein CJ. Exogenous thioredoxin reduces inflammation in autoimmune myocarditis. Circulation. 110: 1178-9. PMID 15353510 DOI: 10.1161/01.CIR.0000143048.05940.0D  0.48
2004 Padalko E, Ohnishi T, Matsushita K, Sun H, Fox-Talbot K, Bao C, Baldwin WM, Lowenstein CJ. Peroxynitrite inhibition of Coxsackievirus infection by prevention of viral RNA entry. Proceedings of the National Academy of Sciences of the United States of America. 101: 11731-6. PMID 15286280 DOI: 10.1073/pnas.0400518101  0.48
2004 Matsushita K, Morrell CN, Lowenstein CJ. Sphingosine 1-phosphate activates Weibel-Palade body exocytosis. Proceedings of the National Academy of Sciences of the United States of America. 101: 11483-7. PMID 15273282 DOI: 10.1073/pnas.0400185101  0.48
2004 Bhatia R, Matsushita K, Yamakuchi M, Morrell CN, Cao W, Lowenstein CJ. Ceramide triggers Weibel-Palade body exocytosis. Circulation Research. 95: 319-24. PMID 15217913 DOI: 10.1161/01.RES.0000136519.84279.7a  0.48
2004 Lowenstein CJ, Padalko E. iNOS (NOS2) at a glance. Journal of Cell Science. 117: 2865-7. PMID 15197240 DOI: 10.1242/jcs.01166  0.48
2004 Gellman J, Hare JM, Lowenstein CJ, Gerstenblith G, Coombs V, Langenberg P, Brinker JA, Resar JR. L-arginine ameliorates the abnormal sympathetic response of the dysfunctional human coronary microvasculature. Angiology. 55: 1-8. PMID 14759083  0.48
2003 Matsushita K, Morrell CN, Cambien B, Yang SX, Yamakuchi M, Bao C, Hara MR, Quick RA, Cao W, O'Rourke B, Lowenstein JM, Pevsner J, Wagner DD, Lowenstein CJ. Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor. Cell. 115: 139-50. PMID 14567912 DOI: 10.1016/S0092-8674(03)00803-1  0.48
2003 Cao W, Baniecki ML, McGrath WJ, Bao C, Deming CB, Rade JJ, Lowenstein CJ, Mangel WF. Nitric oxide inhibits the adenovirus proteinase in vitro and viral infectivity in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 2345-6. PMID 14525937 DOI: 10.1096/fj.03-0396fje  0.48
2003 Cao W, Bao C, Lowenstein CJ. Inducible nitric oxide synthase expression inhibition by adenovirus E1A. Proceedings of the National Academy of Sciences of the United States of America. 100: 7773-8. PMID 12808130 DOI: 10.1073/pnas.1337185100  0.48
2003 Li Q, Guo Y, Xuan YT, Lowenstein CJ, Stevenson SC, Prabhu SD, Wu WJ, Zhu Y, Bolli R. Gene therapy with inducible nitric oxide synthase protects against myocardial infarction via a cyclooxygenase-2-dependent mechanism. Circulation Research. 92: 741-8. PMID 12702642 DOI: 10.1161/01.RES.0000065441.72685.29  0.48
2002 Saura M, Zaragoza C, Cao W, Bao C, Rodríguez-Puyol M, Rodríguez-Puyol D, Lowenstein CJ. Smad2 mediates transforming growth factor-beta induction of endothelial nitric oxide synthase expression. Circulation Research. 91: 806-13. PMID 12411395 DOI: 10.1161/01.RES.0000040397.23817.E5  0.48
2002 Lowenstein CJ. Measuring reactive oxygen species inhibition of endothelin-converting enzyme. Methods in Enzymology. 353: 263-8. PMID 12078501 DOI: 10.1016/S0076-6879(02)53054-8  0.48
2002 Lowenstein CJ. Purification and assessment of proteins associated with nitric oxide synthase. Methods in Enzymology. 353: 233-40. PMID 12078498 DOI: 10.1016/S0076-6879(02)53051-2  0.48
2002 Cao W, Mattagajasingh SN, Xu H, Kim K, Fierlbeck W, Deng J, Lowenstein CJ, Ballermann BJ. TIMAP, a novel CAAX box protein regulated by TGF-beta1 and expressed in endothelial cells. American Journal of Physiology. Cell Physiology. 283: C327-37. PMID 12055102 DOI: 10.1152/ajpcell.00442.2001  0.48
2002 López-Ongil S, Saura M, Zaragoza C, Gónzalez-Santiago L, Rodríguez-Puyol M, Lowenstein CJ, Rodríguez-Puyol D. Hydrogen peroxide regulation of bovine endothelin-converting enzyme-1 Free Radical Biology and Medicine. 32: 406-413. PMID 11864780 DOI: 10.1016/S0891-5849(01)00822-X  0.48
2001 Qian Z, Gelzer-Bell R, Yang SX, Cao W, Ohnishi T, Wasowska BA, Hruban RH, Rodriguez ER, Baldwin WM, Lowenstein CJ. Inducible nitric oxide synthase inhibition of weibel-palade body release in cardiac transplant rejection Circulation. 104: 2369-2375. PMID 11696480  0.48
2001 Tendler DS, Bao C, Wang T, Huang EL, Ratovitski EA, Pardoll DA, Lowenstein CJ. Intersection of interferon and hypoxia signal transduction pathways in nitric oxide-induced tumor apoptosis Cancer Research. 61: 3682-3688. PMID 11325839  0.48
2001 Ozaki M, Deshpande S, Angkeow P, Bellan J, Lowenstein CJ, Dinauer MC, Goldschmidt-Clermont P, Suzuki S, Irani K. Targeted inhibition of the small GTPase protects against ischemia/reperfusion liver injury in mice Transplantation Proceedings. 33: 863-864. PMID 11267105 DOI: 10.1016/S0041-1345(00)02352-6  0.48
2001 Sun B, Fan H, Honda T, Fujimaki R, Lafond-Walker A, Masui Y, Lowenstein CJ, Becker LC. Activation of NFκB and expression of ICAM-1 in ischemic-reperfused canine myocardium Journal of Molecular and Cellular Cardiology. 33: 109-119. PMID 11133227 DOI: 10.1006/jmcc.2000.1280  0.48
2001 Rothstein NM, Quinn TC, Madico G, Gaydos CA, Lowenstein CJ. Effect of azithromycin on murine arteriosclerosis exacerbated by Chlamydia pneumomiae Journal of Infectious Diseases. 183: 232-238. PMID 11120929 DOI: 10.1086/317941  0.48
2000 Horton MR, Olman MA, Bao C, White KE, Choi AMK, Chin BY, Noble PW, Lowenstein CJ. Regulation of plasminogen activator inhibitor-1 and urokinase by hyaluronan fragments in mouse macrophages American Journal of Physiology - Lung Cellular and Molecular Physiology. 279. PMID 11000131  0.48
2000 German Z, Chambliss KL, Pace MC, Arnet UA, Lowenstein CJ, Shaul PW. Molecular basis of cell-specific endothelial nitric-oxide synthase expression in airway epithelium. The Journal of Biological Chemistry. 275: 8183-9. PMID 10713142 DOI: 10.1074/jbc.275.11.8183  0.48
2000 Ozaki M, Deshpande SS, Angkeow P, Bellan J, Lowenstein CJ, Dinauer MC, Goldschmidt-Clermont PJ, Irani K. Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion-induced necrosis and apoptosis in vivo Faseb Journal. 14: 418-429. PMID 10657998  0.48
1999 Zaragoza C, Ocampo CJ, Saura M, Bao C, Leppo M, Lafond-Walker A, Thiemann DR, Hruban R, Lowenstein CJ. Inducible nitric oxide synthase protection against Coxsackievirus pancreatitis Journal of Immunology. 163: 5497-5504. PMID 10553076  0.48
1999 Ratovitski EA, Bao C, Quick RA, McMillan A, Kozlovsky C, Lowenstein CJ. An inducible nitric-oxide synthase (NOS)-associated protein inhibits NOS dimerization and activity Journal of Biological Chemistry. 274: 30250-30257. PMID 10514518 DOI: 10.1074/jbc.274.42.30250  0.48
1999 Lowenstein CJ. NO news is good news Proceedings of the National Academy of Sciences of the United States of America. 96: 10953-10954. PMID 10500105 DOI: 10.1073/pnas.96.20.10953  0.48
1999 Saura M, Zaragoza C, Bao C, McMillan A, Lowenstein CJ. Interaction of Interferon Regulatory Factor-1 and Nuclear Factor κB during activation of inducible nitric oxide synthase transcription Journal of Molecular Biology. 289: 459-471. PMID 10356322 DOI: 10.1006/jmbi.1999.2752  0.48
1999 Horton MR, Shapiro S, Bao C, Lowenstein CJ, Noble PW. Induction and regulation of macrophage metalloelastase by hyaluronan fragments in mouse macrophages Journal of Immunology. 162: 4171-4176. PMID 10201943  0.48
1999 Tseng EE, Brock MV, Lange MS, Troncoso JC, Lowenstein CJ, Blue ME, Johnston MV, Baumgartner WA. Nitric oxide mediates neurologic injury after hypothermic circulatory arrest. The Annals of Thoracic Surgery. 67: 65-71. PMID 10086526 DOI: 10.1016/S0003-4975(98)01363-0  0.48
1999 Saura M, Zaragoza C, McMillan A, Quick RA, Hohenadl C, Lowenstein JM, Lowenstein CJ. An antiviral mechanism of nitric oxide: Inhibition of a viral protease Immunity. 10: 21-28. PMID 10023767 DOI: 10.1016/S1074-7613(00)80003-5  0.48
1999 Ratovitski EA, Alam MR, Quick RA, McMillan A, Bao C, Kozlovsky C, Hand TA, Johnson RC, Mains RE, Eipper BA, Lowenstein CJ. Kalirin inhibition of inducible nitric-oxide synthase. The Journal of Biological Chemistry. 274: 993-9. PMID 9873042 DOI: 10.1074/jbc.274.2.993  0.48
1998 Tanaka K, Pracyk JB, Takeda K, Yu ZX, Ferrans VJ, Deshpande SS, Ozaki M, Hwang PM, Lowenstein CJ, Irani K, Finkel T. Expression of Id1 results in apoptosis of cardiac myocytes through a redox-dependent mechanism Journal of Biological Chemistry. 273: 25922-25928. PMID 9748268 DOI: 10.1074/jbc.273.40.25922  0.48
1998 Tseng EE, Brock MV, Lange MS, Troncoso JC, Blue ME, Lowenstein CJ, Johnston MV, Baumgartner WA. Monosialoganglioside GM1 inhibits neurotoxicity after hypothermic circulatory arrest. Surgery. 124: 298-306. PMID 9706152 DOI: 10.1016/S0039-6060(98)70134-5  0.48
1998 Zaragoza C, Ocampo C, Saura M, Leppo M, Wei XQ, Quick R, Moncada S, Liew FY, Lowenstein CJ. The role of inducible nitric oxide synthase in the host response to Coxsackievirus myocarditis nitric oxide Proceedings of the National Academy of Sciences of the United States of America. 95: 2469-2474. PMID 9482909 DOI: 10.1073/pnas.95.5.2469  0.48
1998 Saura M, Zaragoza C, Díaz-Cazorla M, Hernández-Perera O, Eng E, Lowenstein CJ, Pérez-Sala D, Lamas S. Involvement of transcriptional mechanisms in the inhibition of NOS2 expression by dexamethasone in rat mesangial cells Kidney International. 53: 38-49. PMID 9452998 DOI: 10.1046/j.1523-1755.1998.00725.x  0.48
1998 Ratovitski EA, Kotzbauer PT, Milbrandt J, Lowenstein CJ, Burrow CR. Midkine induces tumor cell proliferation and binds to a high affinity signaling receptor associated with JAK tyrosine kinases Journal of Biological Chemistry. 273: 3654-3660. PMID 9452495 DOI: 10.1074/jbc.273.6.3654  0.48
1997 Tseng EE, Brock MV, Lange MS, Blue ME, Troncoso JC, Kwon CC, Lowenstein CJ, Johnston MV, Baumgartner WA. Neuronal nitric oxide synthase inhibition reduces neuronal apoptosis after hypothermic circulatory arrest. The Annals of Thoracic Surgery. 64: 1639-47. PMID 9436549 DOI: 10.1016/S0003-4975(97)01110-7  0.48
1997 Lafond-Walker A, Chen CL, Augustine S, Wu TC, Hruban RH, Lowenstein CJ. Inducible nitric oxide synthase expression in coronary arteries of transplanted human hearts with accelerated graft arteriosclerosis American Journal of Pathology. 151: 919-925. PMID 9327724  0.48
1997 Zaragoza C, Ocampo CJ, Saura M, McMillan A, Lowenstein CJ. Nitric oxide inhibition of coxsackievirus replication in vitro Journal of Clinical Investigation. 100: 1760-1767. PMID 9312175  0.48
1997 Amin AR, Patel RN, Thakker GD, Lowenstein CJ, Attur MG, Abramson SB. Post-transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines Febs Letters. 410: 259-264. PMID 9237641 DOI: 10.1016/S0014-5793(97)00605-4  0.48
1997 Merrill JE, Murphy SP, Mitrovic B, Mackenzie-Graham A, Dopp JC, Ding M, Griscavage J, Ignarro LJ, Lowenstein CJ. Inducible nitric oxide synthase and nitric oxide production by oligodendrocytes Journal of Neuroscience Research. 48: 372-384. PMID 9169863 DOI: 10.1002/(SICI)1097-4547(19970515)48:4<372::AID-JNR9>3.0.CO;2-8  0.48
1997 McKee CM, Lowenstein CJ, Horton MR, Wu J, Bao C, Chin BY, Choi AMK, Noble PW. Hyaluronan fragments induce nitric-oxide synthase in murine macrophages through a nuclear factor κB-dependent mechanism Journal of Biological Chemistry. 272: 8013-8018. PMID 9065473 DOI: 10.1074/jbc.272.12.8013  0.48
1996 Brock MV, Blue ME, Lowenstein CJ, Northington FA, Lange MS, Johnston MV, Baumgartner WA. Induction of neuronal nitric oxide after hypothermic circulatory arrest. The Annals of Thoracic Surgery. 62: 1313-20. PMID 8893562 DOI: 10.1016/0003-4975(96)00775-8  0.48
1996 Wong HR, Finder JD, Wasserloos K, Lowenstein CJ, Geller DA, Billiar TR, Pitt BR, Davies P. Transcriptional regulation of iNOS by IL-1 beta in cultured rat pulmonary artery smooth muscle cells. The American Journal of Physiology. 271: L166-71. PMID 8760147  0.48
1996 Perrella MA, Hsieh CM, Lee WS, Shieh S, Tsai JC, Patterson C, Lowenstein CJ, Long NC, Haber E, Shore S, Lee ME. Arrest of endotoxin-induced hypotension by transforming growth factor beta1. Proceedings of the National Academy of Sciences of the United States of America. 93: 2054-9. PMID 8700884 DOI: 10.1073/pnas.93.5.2054  0.48
1996 Arnet UA, McMillan A, Dinerman JL, Ballermann B, Lowenstein CJ. Regulation of endothelial nitric-oxide synthase during hypoxia Journal of Biological Chemistry. 271: 15069-15073. PMID 8663208 DOI: 10.1074/jbc.271.25.15069  0.48
1996 Lowenstein CJ, Hill SL, Lafond-Walker A, Wu J, Allen G, Landavere M, Rose NR, Herskowitz A. Nitric oxide inhibits viral replication in murine myocarditis. The Journal of Clinical Investigation. 97: 1837-43. PMID 8621766 DOI: 10.1172/JCI118613  0.48
1996 Wong HR, Finder JD, Wasserloos K, Lowenstein CJ, Geller DA, Billiar TR, Pitt BR, Davies P. Transcriptional regulation of iNOS by IL-1β in cultured rat pulmonary artery smooth muscle cells American Journal of Physiology. 271: L172-L177.  0.48
1995 Day JD, Rayburn BK, Gaudin PB, Baldwin WM, Lowenstein CJ, Kasper EK, Baughman KL, Baumgartner WA, Hutchins GM, Hruban RH. Cardiac allograft vasculopathy: The central pathogenetic role of ischemia- induced endothelial cell injury Journal of Heart and Lung Transplantation. 14. PMID 8719476  0.48
1995 Ungureanu-Longrois D, Balligand JL, Simmons WW, Okada I, Kobzik L, Lowenstein CJ, Kunkel SL, Michel T, Kelly RA, Smith TW. Induction of nitric oxide synthase activity by cytokines in ventricular myocytes is necessary but not sufficient to decrease contractile responsiveness to beta-adrenergic agonists. Circulation Research. 77: 494-502. PMID 7543826  0.48
1995 Ungureanu-Longrois D, Balligand JL, Okada I, Simmons WW, Kobzik L, Lowenstein CJ, Kunkel SL, Michel T, Kelly RA, Smith TW. Contractile responsiveness of ventricular myocytes to isoproterenol is regulated by induction of nitric oxide synthase activity in cardiac microvascular endothelial cells in heterotypic primary culture. Circulation Research. 77: 486-93. PMID 7543825  0.48
1995 Shaul PW, North AJ, Brannon TS, Ujiie K, Wells LB, Nisen PA, Lowenstein CJ, Snyder SH, Star RA. Prolonged in vivo hypoxia enhances nitric oxide synthase type I and type III gene expression in adult rat lung. American Journal of Respiratory Cell and Molecular Biology. 13: 167-74. PMID 7542896 DOI: 10.1165/ajrcmb.13.2.7542896  0.48
1995 Flynn JL, Goldstein MM, Chan J, Triebold KJ, Pfeffer K, Lowenstein CJ, Schrelber R, Mak TW, Bloom BR. Tumor necrosis factor-α is required in the protective immune response against mycobacterium tuberculosis in mice Immunity. 2: 561-572. PMID 7540941 DOI: 10.1016/1074-7613(95)90001-2  0.48
1995 Balligand JL, Ungureanu-Longrois D, Simmons WW, Kobzik L, Lowenstein CJ, Lamas S, Kelly RA, Smith TW, Michel T. Induction of NO synthase in rat cardiac microvascular endothelial cells by IL-1 beta and IFN-gamma. The American Journal of Physiology. 268: H1293-303. PMID 7535006  0.48
1995 Lomis TJ, Siffring CW, Chalasani S, Ziegler DW, Lentz KE, Stauffer KE, McMillan A, Agarwal N, Lowenstein CJ, Rhoads JE. First place winner of the Conrad Jobst Award in the gold medal paper competition. Nitric oxide synthase inhibitors N-monomethylarginine and aminoguanidine prevent the progressive and severe hypotension associated with a rat model of pancreatitis. The American Surgeon. 61: 7-10. PMID 7530415  0.48
1995 Freeman JE, Kuo WY, Milligan G, Lowenstein CJ, Levine MA, Flavahan NA. Analysis of Pertussis Toxin-Sensitive Receptor: G-Protein Interactions in Native Porcine Endothelial Cells Endothelium. 3: 321-330. DOI: 10.3109/10623329509024674  0.48
1994 Lowenstein CJ, Dinerman JL, Snyder SH. Nitric oxide: A physiologic messenger Annals of Internal Medicine. 120: 227-237. PMID 8273987  0.48
1994 Wynn TA, Oswald IP, Eltoum IA, Caspar P, Lowenstein CJ, Lewis FA, James SL, Sher A. Elevated expression of Th1 cytokines and nitric oxide synthase in the lungs of vaccinated mice after challenge infection with Schistosoma mansoni Journal of Immunology. 153: 5200-5209. PMID 7525727  0.48
1994 Balligand JL, Ungureanu-Longrois D, Simmons WW, Pimental D, Malinski TA, Kapturczak M, Taha Z, Lowenstein CJ, Davidoff AJ, Kelly RA. Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro. The Journal of Biological Chemistry. 269: 27580-8. PMID 7525557  0.48
1994 Felley-Bosco E, Ambs S, Lowenstein CJ, Keefer LK, Harris CC. Constitutive expression of inducible nitric oxide synthase in human bronchial epithelial cells induces c-fos and stimulates the cGMP pathway American Journal of Respiratory Cell and Molecular Biology. 11: 159-164. PMID 7519434  0.48
1994 North AJ, Star RA, Brannon TS, Ujiie K, Wells LB, Lowenstein CJ, Snyder SH, Shaul PW. Nitric oxide synthase type I and type III gene expression are developmentally regulated in rat lung. The American Journal of Physiology. 266: L635-41. PMID 7517640  0.48
1994 Lowenstein CJ, Snyder SH. Purification, cloning, and expression of nitric-oxide synthase Methods in Enzymology. 233: 264-269. PMID 7517001 DOI: 10.1016/S0076-6879(94)33030-1  0.48
1994 Johnson BA, Lowenstein CJ, Schwarz MA, Nakayama DK, Pitt BR, Davies P. Culture of pulmonary microvascular smooth muscle cells from intraacinar arteries of the rat: characterization and inducible production of nitric oxide. American Journal of Respiratory Cell and Molecular Biology. 10: 604-12. PMID 7516171 DOI: 10.1165/ajrcmb.10.6.7516171  0.48
1994 Pace JL, Lowenstein CJ, Phillips TA, Chen LC, Morrison DC, Hunt JS, Russell SW. Population dynamics of inducible nitric oxide synthase production by LPSand LPS/Ifnγ-stimulated mouse macrophages Journal of Endotoxin Research. 1: 227-233. DOI: 10.1177/096805199400100404  0.48
1994 North AJ, Star RA, Brannon TS, Ujiie K, Wells LB, Lowenstein CJ, Snyder SH, Shaul PW. Nitric oxide synthase type I and type III gene expression are developmentally regulated in rat lung Am.J.Physiol.. 266.  0.48
1993 Lowenstein CJ, Alley EW, Raval P, Snowman AM, Snyder SH, Russell SW, Murphy WJ. Macrophage nitric oxide synthase gene: Two upstream regions mediate induction by interferon γ and lipopolysaccharide Proceedings of the National Academy of Sciences of the United States of America. 90: 9730-9734. PMID 7692452  0.48
1993 Vanderwinden JM, De Laet MH, Schiffmann SN, Mailleux P, Lowenstein CJ, Snyder SH, Vanderhaeghen JJ. Nitric oxide synthase distribution in the enteric nervous system of Hirschsprung's disease Gastroenterology. 105: 969-973. PMID 7691675  0.48
1993 Kobzik L, Bredt DS, Lowenstein CJ, Drazen J, Gaston B, Sugarbaker D, Stamler JS. Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization. American Journal of Respiratory Cell and Molecular Biology. 9: 371-7. PMID 7691109 DOI: 10.1165/ajrcmb/9.4.371  0.48
1993 Dinerman JL, Lowenstein CJ, Snyder SH. Molecular mechanisms of nitric oxide regulation: Potential relevance to cardiovascular disease Circulation Research. 73: 217-222. PMID 7687202  0.48
1993 Burnett AL, Tillman SL, Chang TS, Epstein JI, Lowenstein CJ, Bredt DS, Snyder SH, Walsh PC. Immunohistochemical localization of nitric oxide synthase in the autonomic innervation of the human penis. The Journal of Urology. 150: 73-6. PMID 7685426  0.48
1993 Geller DA, Lowenstein CJ, Shapiro RA, Nussler AK, Di Silvio M, Wang SC, Nakayama DK, Simmons RL, Snyder SH, Billiar TR. Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 90: 3491-5. PMID 7682706  0.48
1993 Geller DA, Nussler AK, Di Silvio M, Lowenstein CJ, Shapiro RA, Wang SC, Simmons RL, Billiar TR. Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes Proceedings of the National Academy of Sciences of the United States of America. 90: 522-526. PMID 7678458  0.48
1993 Lorsbach RB, Murphy WJ, Lowenstein CJ, Snyder SH, Russell SW. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing: Molecular basis for the synergy between interferon-γ and lipopolysaccharide Journal of Biological Chemistry. 268: 1908-1913. PMID 7678412  0.48
1992 Nakayama DK, Geller DA, Lowenstein CJ, Chern HD, Davies P, Pitt BR, Simmons RL, Billiar TR. Cytokines and lipopolysaccharide induce nitric oxide synthase in cultured rat pulmonary artery smooth muscle. American Journal of Respiratory Cell and Molecular Biology. 7: 471-6. PMID 1384580 DOI: 10.1165/ajrcmb/7.5.471  0.48
1992 Lowenstein CJ, Snyder SH. Nitric oxide, a novel biologic messenger Cell. 70: 705-707. PMID 1381285 DOI: 10.1016/0092-8674(92)90301-R  0.48
1992 Lowenstein CJ, Glatt CS, Bredt DS, Snyder SH. Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme. Proceedings of the National Academy of Sciences of the United States of America. 89: 6711-5. PMID 1379716  0.48
1992 Burnett AL, Lowenstein CJ, Bredt DS, Chang TS, Snyder SH. Nitric oxide: a physiologic mediator of penile erection. Science (New York, N.Y.). 257: 401-3. PMID 1378650  0.48
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