Year |
Citation |
Score |
2013 |
Alexander S, Swatson WS, Alexander H. Pharmacogenetics of resistance to Cisplatin and other anticancer drugs and the role of sphingolipid metabolism. Methods in Molecular Biology (Clifton, N.J.). 983: 185-204. PMID 23494308 DOI: 10.1007/978-1-62703-302-2_10 |
0.339 |
|
2011 |
Alexander S, Alexander H. Lead genetic studies in Dictyostelium discoideum and translational studies in human cells demonstrate that sphingolipids are key regulators of sensitivity to cisplatin and other anticancer drugs. Seminars in Cell & Developmental Biology. 22: 97-104. PMID 20951822 DOI: 10.1016/J.Semcdb.2010.10.005 |
0.358 |
|
2010 |
Sridevi P, Alexander H, Laviad EL, Min J, Mesika A, Hannink M, Futerman AH, Alexander S. Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing. Experimental Cell Research. 316: 78-91. PMID 19800881 DOI: 10.1016/J.Yexcr.2009.09.027 |
0.321 |
|
2009 |
Sridevi P, Alexander H, Laviad EL, Pewzner-Jung Y, Hannink M, Futerman AH, Alexander S. Ceramide synthase 1 is regulated by proteasomal mediated turnover. Biochimica Et Biophysica Acta. 1793: 1218-27. PMID 19393694 DOI: 10.1016/J.Bbamcr.2009.04.006 |
0.36 |
|
2007 |
Van Driessche N, Alexander H, Min J, Kuspa A, Alexander S, Shaulsky G. Global transcriptional responses to cisplatin in Dictyostelium discoideum identify potential drug targets. Proceedings of the National Academy of Sciences of the United States of America. 104: 15406-11. PMID 17878305 DOI: 10.1073/Pnas.0705996104 |
0.349 |
|
2007 |
Min J, Mesika A, Sivaguru M, Van Veldhoven PP, Alexander H, Futerman AH, Alexander S. (Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1. Molecular Cancer Research : McR. 5: 801-12. PMID 17699106 DOI: 10.1158/1541-7786.Mcr-07-0100 |
0.329 |
|
2005 |
Min J, Van Veldhoven PP, Zhang L, Hanigan MH, Alexander H, Alexander S. Sphingosine-1-phosphate lyase regulates sensitivity of human cells to select chemotherapy drugs in a p38-dependent manner. Molecular Cancer Research : McR. 3: 287-96. PMID 15886300 DOI: 10.1158/1541-7786.Mcr-04-0197 |
0.324 |
|
2005 |
Min J, Traynor D, Stegner AL, Zhang L, Hanigan MH, Alexander H, Alexander S. Sphingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to the anticancer drug cisplatin. Eukaryotic Cell. 4: 178-89. PMID 15643073 DOI: 10.1128/Ec.4.1.178-189.2005 |
0.318 |
|
2004 |
Min J, Stegner AL, Alexander H, Alexander S. Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum-based chemotherapy drugs. Eukaryotic Cell. 3: 795-805. PMID 15190000 DOI: 10.1128/Ec.3.3.795-805.2004 |
0.323 |
|
2003 |
Alexander S, Srinivasan S, Alexander H. Proteomics opens doors to the mechanisms of developmentally regulated secretion. Molecular & Cellular Proteomics : McP. 2: 1156-63. PMID 14504294 DOI: 10.1074/Mcp.R300011-Mcp200 |
0.582 |
|
2003 |
Garcia MX, Alexander H, Mahadeo D, Cotter DA, Alexander S. The Dictyostelium discoideum prespore-specific catalase B functions to control late development and to protect spore viability. Biochimica Et Biophysica Acta. 1641: 55-64. PMID 12788229 DOI: 10.1016/S0167-4889(03)00064-8 |
0.332 |
|
2002 |
Garcia MX, Roberts C, Alexander H, Stewart AM, Harwood A, Alexander S, Insall RH. Methanol and acriflavine resistance in Dictyostelium are caused by loss of catalase. Microbiology (Reading, England). 148: 333-40. PMID 11782526 DOI: 10.1099/00221287-148-1-333 |
0.309 |
|
2001 |
Srinivasan S, Traini M, Herbert B, Sexton D, Harry J, Alexander H, Williams KL, Alexander S. Proteomic analysis of a developmentally regulated secretory vesicle. Proteomics. 1: 1119-27. PMID 11990506 DOI: 10.1002/1615-9861(200109)1:9<1119::Aid-Prot1119>3.0.Co;2-X |
0.586 |
|
2001 |
Li G, Foote C, Alexander S, Alexander H. Sphingosine-1-phosphate lyase has a central role in the development of Dictyostelium discoideum. Development (Cambridge, England). 128: 3473-83. PMID 11566853 |
0.486 |
|
2000 |
Garcia MX, Foote C, van Es S, Devreotes PN, Alexander S, Alexander H. Differential developmental expression and cell type specificity of Dictyostelium catalases and their response to oxidative stress and UV-light. Biochimica Et Biophysica Acta. 1492: 295-310. PMID 11004503 DOI: 10.1016/S0167-4781(00)00063-4 |
0.314 |
|
2000 |
Li G, Alexander H, Schneider N, Alexander S. Molecular basis for resistance to the anticancer drug cisplatin in Dictyostelium. Microbiology (Reading, England). 146: 2219-27. PMID 10974109 DOI: 10.1099/00221287-146-9-2219 |
0.538 |
|
2000 |
Srinivasan S, Alexander H, Alexander S. Crossing the finish line of development: regulated secretion of Dictyostelium proteins. Trends in Cell Biology. 10: 215-9. PMID 10802536 DOI: 10.1016/S0962-8924(00)01758-X |
0.565 |
|
2000 |
Srinivasan S, Alexander H, Alexander S. The Dictyostelium fruiting body – a structure of cells and cellulose Trends in Cell Biology. 10: 315. DOI: 10.1016/S0962-8924(00)01775-X |
0.482 |
|
1999 |
Srinivasan S, Alexander H, Alexander S. The prespore vesicles of Dictyostelium discoideum. Purification, characterization, and developmental regulation. The Journal of Biological Chemistry. 274: 35823-31. PMID 10585466 DOI: 10.1074/Jbc.274.50.35823 |
0.572 |
|
1998 |
Yu SL, Lee SK, Alexander H, Alexander S. Rapid changes of nucleotide excision repair gene expression following UV-irradiation and cisplatin treatment of Dictyostelium discoideum. Nucleic Acids Research. 26: 3397-403. PMID 9649625 DOI: 10.1093/Nar/26.14.3397 |
0.31 |
|
1997 |
Lee SK, Li G, Yu SL, Alexander H, Alexander S. The Dictyostelium discoideum beta-1,4-mannosyltransferase gene, mntA, has two periods of developmental expression. Gene. 204: 251-8. PMID 9434191 DOI: 10.1016/S0378-1119(97)00553-2 |
0.533 |
|
1997 |
Lee SK, Yu SL, Garcia MX, Alexander H, Alexander S. Differential developmental expression of the rep B and rep D xeroderma pigmentosum related DNA helicase genes from Dictyostelium discoideum. Nucleic Acids Research. 25: 2365-74. PMID 9171087 DOI: 10.1093/Nar/25.12.2365 |
0.345 |
|
1996 |
Alexander H, Lee SK, Yu SL, Alexander S. repE--the Dictyostelium homolog of the human xeroderma pigmentosum group E gene is developmentally regulated and contains a leucine zipper motif. Nucleic Acids Research. 24: 2295-301. PMID 8710499 DOI: 10.1093/Nar/24.12.2295 |
0.359 |
|
1992 |
Alexander H, Alexander S, Getzoff ED, Tainer JA, Geysen HM, Lerner RA. Altering the antigenicity of proteins Proceedings of the National Academy of Sciences of the United States of America. 89: 3352-3356. PMID 1373498 DOI: 10.1073/Pnas.89.8.3352 |
0.347 |
|
1991 |
Alexander H, Alexander S, Heffron F, Fieser TM, Hay BN, Getzoff ED, Tainer JA, Lerner RA. Synthesis and characterization of a recombinant myohemerythrin protein encoded by a synthetic gene Gene. 99: 151-156. PMID 1708739 DOI: 10.1016/0378-1119(91)90121-Q |
0.388 |
|
1988 |
Ricksten A, Kallin B, Alexander H, Dillner J, Fåhraeus R, Klein G, Lerner R, Rymo L. BamHI E region of the Epstein-Barr virus genome encodes three transformation-associated nuclear proteins. Proceedings of the National Academy of Sciences of the United States of America. 85: 995-9. PMID 2829223 DOI: 10.1073/Pnas.85.4.995 |
0.328 |
|
1987 |
Getzoff ED, Geysen HM, Rodda SJ, Alexander H, Tainer JA, Lerner RA. Mechanisms of antibody binding to a protein Science. 235: 1191-1196. PMID 3823879 DOI: 10.1126/Science.3823879 |
0.319 |
|
1987 |
Geysen HM, Tainer JA, Rodda SJ, Mason TJ, Alexander H, Getzoff ED, Lerner RA. Chemistry of antibody binding to a protein Science. 235: 1184-1190. PMID 3823878 DOI: 10.1126/Science.3823878 |
0.325 |
|
1986 |
Dillner J, Kallin B, Alexander H, Ernberg I, Uno M, Ono Y, Klein G, Lerner RA. An Epstein-Barr virus (EBV)-determined nuclear antigen (EBNA5) partly encoded by the transformation-associated Bam WYH region of EBV DNA: preferential expression in lymphoblastoid cell lines. Proceedings of the National Academy of Sciences of the United States of America. 83: 6641-5. PMID 3018741 DOI: 10.1073/Pnas.83.17.6641 |
0.31 |
|
1985 |
Dillner J, Kallin B, Klein G, Jörnvall H, Alexander H, Lerner R. Antibodies against synthetic peptides react with the second Epstein-Barr virus-associated nuclear antigen. The Embo Journal. 4: 1813-1818. DOI: 10.1002/J.1460-2075.1985.Tb03855.X |
0.302 |
|
1984 |
Tainer JA, Getzoff ED, Alexander H, Houghten RA, Olson AJ, Lerner RA, Hendrickson WA. The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein Nature. 312: 127-134. PMID 6209578 DOI: 10.1038/312127A0 |
0.314 |
|
1984 |
Dillner J, Sternås L, Kallin B, Alexander H, Ehlin-Henriksson B, Jörnvall H, Klein G, Lerner R. Antibodies against a synthetic peptide identify the Epstein-Barr virus-determined nuclear antigen. Proceedings of the National Academy of Sciences of the United States of America. 81: 4652-6. PMID 6205400 DOI: 10.1073/Pnas.81.15.4652 |
0.302 |
|
1983 |
Alexander H, Johnson DA, Rosen J, Jerabek L, Green N, Weissman IL, Lerner RA. Mimicking the alloantigenicity of proteins with chemically synthesized peptides differing in single amino acids. Nature. 306: 697-9. PMID 6656870 DOI: 10.1038/306697A0 |
0.343 |
|
1983 |
Gerin JL, Alexander H, Shih JW, Purcell RH, Dapolito G, Engle R, Green N, Sutcliffe JG, Shinnick TM, Lerner RA. Chemically synthesized peptides of hepatitis B surface antigen duplicate the d/y specificities and induce subtype-specific antibodies in chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 80: 2365-9. PMID 6188163 DOI: 10.1073/Pnas.80.8.2365 |
0.302 |
|
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