Roger C. Levesque - Publications

Universite Laval (Canada) 
Microbiology Biology

138 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Crouse A, Schramm C, Emond-Rheault JG, Herod A, Kerhoas M, Rohde J, Gruenheid S, Kukavica-Ibrulj I, Boyle B, Greenwood CMT, Goodridge LD, Garduno R, Levesque RC, Malo D, Daigle F. Combining Whole-Genome Sequencing and Multimodel Phenotyping To Identify Genetic Predictors of Virulence. Msphere. 5. PMID 32522778 DOI: 10.1128/mSphere.00293-20  0.64
2020 Soukarieh F, Liu R, Romero M, Roberston SN, Richardson W, Lucanto S, Oton EV, Qudus NR, Mashabi A, Grossman S, Ali S, Sou T, Kukavica-Ibrulj I, Levesque RC, Bergström CAS, et al. Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown . Frontiers in Chemistry. 8: 204. PMID 32432073 DOI: 10.3389/fchem.2020.00204  0.64
2020 Sou TAS, Kukavica-Ibrulj I, Levesque RC, Friberg LE, Bergström CAS. Model-informed drug development in pulmonary delivery: Preclinical pharmacokinetic-pharmacodynamic modelling for evaluation of treatments against chronic Pseudomonas aeruginosa lung infections. Molecular Pharmaceutics. PMID 31951139 DOI: 10.1021/acs.molpharmaceut.9b00968  0.64
2019 Scott A, Pottenger S, Timofte D, Moore M, Wright L, Kukavica-Ibrulj I, Jeukens J, Levesque RC, Freschi L, Pinchbeck GL, Schmidt VM, McEwan N, Radford AD, Fothergill JL. Reservoirs of resistance: polymyxin resistance in veterinary-associated companion animal isolates of . The Veterinary Record. PMID 31239295 DOI: 10.1136/vr.105075  0.64
2019 Jeukens J, Freschi L, Kukavica-Ibrulj I, Emond-Rheault JG, Allard C, Barbeau J, Cantin A, Charette SJ, Déziel E, Malouin F, Milot J, Nguyen D, Popa C, Boyle B, Levesque RC. The population among Cystic Fibrosis patients in Quebec, Canada: a disease hotspot without known epidemic isolates. Journal of Clinical Microbiology. PMID 30944192 DOI: 10.1128/JCM.02019-18  0.64
2019 Jeukens J, Emond-Rheault JG, Freschi L, Kukavica-Ibrulj I, Levesque RC. Major Release of 161 Whole-Genome Sequences from the International Consortium Database. Microbiology Resource Announcements. 8. PMID 30923236 DOI: 10.1128/MRA.00013-19  0.64
2018 Freschi L, Vincent AT, Jeukens J, Emond-Rheault JG, Kukavica-Ibrulj I, Dupont MJ, Charette SJ, Boyle B, Levesque RC. The Pseudomonas aeruginosa pan-genome provides new insights on its population structure, horizontal gene transfer and pathogenicity. Genome Biology and Evolution. PMID 30496396 DOI: 10.1093/gbe/evy259  0.64
2018 Sou T, Kukavica-Ibrulj I, Soukarieh F, Halliday N, Levesque RC, Williams P, Stocks M, Cámara M, Friberg LE, Bergström CAS. Model-based drug development in pulmonary delivery: Pharmacokinetic analysis of novel drug candidates for treatment of Pseudomonas aeruginosa lung infection. Journal of Pharmaceutical Sciences. PMID 30257195 DOI: 10.1016/j.xphs.2018.09.017  0.64
2018 Freschi L, Bertelli C, Jeukens J, Moore MP, Kukavica-Ibrulj I, Emond-Rheault JG, Hamel J, Fothergill JL, Tucker NP, McClean S, Klockgether J, de Soyza A, Brinkman FSL, Levesque RC, Winstanley C. Genomic characterisation of an international Pseudomonas aeruginosa reference panel indicates that the two major groups draw upon distinct mobile gene pools. Fems Microbiology Letters. PMID 29897457 DOI: 10.1093/femsle/fny120  0.64
2018 Mottawea W, Duceppe MO, Dupras AA, Usongo V, Jeukens J, Freschi L, Emond-Rheault JG, Hamel J, Kukavica-Ibrulj I, Boyle B, Gill A, Burnett E, Franz E, Arya G, Weadge JT, ... ... Levesque RC, et al. Prophage Sequence Profiles Reflect Genome Diversity and Can Be Used for High Discrimination Subtyping. Frontiers in Microbiology. 9: 836. PMID 29780368 DOI: 10.3389/fmicb.2018.00836  0.64
2018 Gagné-Thivierge C, Kukavica-Ibrulj I, Filion G, Dekimpe V, Tan SGE, Vincent AT, Déziel É, Levesque RC, Charette SJ. A multi-host approach to identify a transposon mutant of Pseudomonas aeruginosa LESB58 lacking full virulence. Bmc Research Notes. 11: 198. PMID 29580289 DOI: 10.1186/s13104-018-3308-7  0.64
2017 Colavecchio A, Leo V, Zaccheo S, Jeukens J, Emond-Rheault JG, Hamel J, Kukavica-Ibrulj I, Levesque RC, Goodridge L. Whole-Genome Sequencing of Lactobacillus Species from Two Commercial Probiotic Products. Genome Announcements. 5. PMID 29122883 DOI: 10.1128/genomeA.01279-17  0.64
2017 Vincent AT, Freschi L, Jeukens J, Kukavica-Ibrulj I, Emond-Rheault JG, Leduc A, Boyle B, Jean-Pierre F, Groleau MC, Déziel E, Barbeau J, Charette SJ, Levesque RC. Genomic characterisation of environmental Pseudomonas aeruginosa isolated from dental unit waterlines revealed the insertion sequence ISPa11 as a chaotropic element. Fems Microbiology Ecology. 93. PMID 28934400 DOI: 10.1093/femsec/fix106  0.64
2017 Colavecchio A, D'Souza Y, Tompkins E, Jeukens J, Freschi L, Emond-Rheault JG, Kukavica-Ibrulj I, Boyle B, Bekal S, Tamber S, Levesque RC, Goodridge LD. Prophage Integrase Typing Is a Useful Indicator of Genomic Diversity in Salmonella enterica. Frontiers in Microbiology. 8: 1283. PMID 28740489 DOI: 10.3389/fmicb.2017.01283  0.64
2017 Emond-Rheault JG, Jeukens J, Freschi L, Kukavica-Ibrulj I, Boyle B, Dupont MJ, Colavecchio A, Barrere V, Cadieux B, Arya G, Bekal S, Berry C, Burnett E, Cavestri C, Chapin TK, ... ... Levesque RC, et al. A Syst-OMICS Approach to Ensuring Food Safety and Reducing the Economic Burden of Salmonellosis. Frontiers in Microbiology. 8: 996. PMID 28626454 DOI: 10.3389/fmicb.2017.00996  0.64
2017 Jeukens J, Freschi L, Kukavica-Ibrulj I, Emond-Rheault JG, Tucker NP, Levesque RC. Genomics of antibiotic-resistance prediction in Pseudomonas aeruginosa. Annals of the New York Academy of Sciences. PMID 28574575 DOI: 10.1111/nyas.13358  0.64
2017 Colavecchio A, Jeukens J, Freschi L, Edmond Rheault JG, Kukavica-Ibrulj I, Levesque RC, LeJeune J, Goodridge L. Complete Genome Sequences of Two Phage-Like Plasmids Carrying the CTX-M-15 Extended-Spectrum β-Lactamase Gene. Genome Announcements. 5. PMID 28495759 DOI: 10.1128/genomeA.00102-17  0.64
2017 Jeukens J, Freschi L, Vincent AT, Emond-Rheault JG, Kukavica-Ibrulj I, Charette SJ, Levesque RC. A Pan-Genomic Approach to Understand the Basis of Host Adaptation in Achromobacter. Genome Biology and Evolution. 9: 1030-1046. PMID 28383665 DOI: 10.1093/gbe/evx061  0.64
2016 Davies EV, James CE, Kukavica-Ibrulj I, Levesque RC, Brockhurst MA, Winstanley C. Temperate phages enhance pathogen fitness in chronic lung infection. The Isme Journal. PMID 27070941 DOI: 10.1038/ismej.2016.51  1
2016 Pham VH, Maaroufi H, Levesque RC, Lapointe J. Cyclic peptides identified by phage display are competitive inhibitors of the tRNA-dependent amidotransferase of Helicobacter pylori. Peptides. PMID 26976271 DOI: 10.1016/j.peptides.2016.03.001  1
2016 Périnet S, Jeukens J, Kukavica-Ibrulj I, Ouellet MM, Charette SJ, Levesque RC. Molybdate transporter ModABC is important for Pseudomonas aeruginosa chronic lung infection. Bmc Research Notes. 9: 23. PMID 26758577 DOI: 10.1186/s13104-016-1840-x  1
2016 Vincent AT, Trudel MV, Freschi L, Nagar V, Gagné-Thivierge C, Levesque RC, Charette SJ. Increasing genomic diversity and evidence of constrained lifestyle evolution due to insertion sequences in Aeromonas salmonicida Bmc Genomics. 17. DOI: 10.1186/s12864-016-2381-3  1
2015 Bianconi I, Jeukens J, Freschi L, Alcalá-Franco B, Facchini M, Boyle B, Molinaro A, Kukavica-Ibrulj I, Tümmler B, Levesque RC, Bragonzi A. Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection. Bmc Genomics. 16: 1105. PMID 26714629 DOI: 10.1186/s12864-015-2276-8  0.64
2015 Landry M, Comeau AM, Derome N, Cusson M, Levesque RC. Composition of the Spruce Budworm (Choristoneura fumiferana) Midgut Microbiota as Affected by Rearing Conditions. Plos One. 10: e0144077. PMID 26636571 DOI: 10.1371/journal.pone.0144077  1
2015 Freschi L, Jeukens J, Kukavica-Ibrulj I, Boyle B, Dupont MJ, Laroche J, Larose S, Maaroufi H, Fothergill JL, Moore M, Winsor GL, Aaron SD, Barbeau J, Bell SC, Burns JL, ... ... Levesque RC, et al. Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium. Frontiers in Microbiology. 6: 1036. PMID 26483767 DOI: 10.3389/fmicb.2015.01036  1
2015 Jeukens J, Kukavica-Ibrulj I, Freschi L, Jabaji S, Levesque RC. Draft Genome Sequences of Two Lipopeptide-Producing Strains of Bacillus methylotrophicus. Genome Announcements. 3. PMID 26450741 DOI: 10.1128/genomeA.01176-15  0.64
2015 Maaroufi H, Levesque RC. Glycoside hydrolase family 32 is present in Bacillus subtilis phages. Virology Journal. 12: 157. PMID 26438422 DOI: 10.1186/s12985-015-0373-6  1
2015 Lemieux AA, Jeukens J, Kukavica-Ibrulj I, Fothergill JL, Boyle B, Laroche J, Tucker NP, Winstanley C, Levesque RC. Genes Required for Free Phage Production are Essential for Pseudomonas aeruginosa Chronic Lung Infections. The Journal of Infectious Diseases. PMID 26268854 DOI: 10.1093/infdis/jiv415  1
2015 Jeukens J, Freschi L, Kukavica-Ibrulj I, Nguyen D, Levesque RC. Draft Genome Sequence of Triclosan-Resistant Cystic Fibrosis Isolate Achromobacter xylosoxidans CF304. Genome Announcements. 3. PMID 26227609 DOI: 10.1128/genomeA.00865-15  0.64
2015 Kukavica-Ibrulj I, Levesque RC. Essential genes in the infection model of Pseudomonas aeruginosa-PCR-based signature-tagged mutagenesis. Methods in Molecular Biology (Clifton, N.J.). 1279: 97-123. PMID 25636615 DOI: 10.1007/978-1-4939-2398-4_7  0.64
2015 Comeau AM, Dufour J, Bouvet GF, Jacobi V, Nigg M, Henrissat B, Laroche J, Levesque RC, Bernier L. Functional annotation of the Ophiostoma novo-ulmi genome: insights into the phytopathogenicity of the fungal agent of Dutch elm disease. Genome Biology and Evolution. 7: 410-30. PMID 25539722 DOI: 10.1093/gbe/evu281  1
2014 Kouidmi I, Levesque RC, Paradis-Bleau C. The biology of Mur ligases as an antibacterial target. Molecular Microbiology. 94: 242-53. PMID 25130693 DOI: 10.1111/mmi.12758  1
2014 Kukavica-Ibrulj I, Facchini M, Cigana C, Levesque RC, Bragonzi A. Assessing Pseudomonas aeruginosa virulence and the host response using murine models of acute and chronic lung infection. Methods in Molecular Biology (Clifton, N.J.). 1149: 757-71. PMID 24818948 DOI: 10.1007/978-1-4939-0473-0_58  1
2014 Jeukens J, Boyle B, Tucker NP, Levesque RC. Strategy for genome sequencing analysis and assembly for comparative genomics of Pseudomonas genomes. Methods in Molecular Biology (Clifton, N.J.). 1149: 565-77. PMID 24818933 DOI: 10.1007/978-1-4939-0473-0_43  1
2014 Kukavica-Ibrulj I, Levesque RC. Signature-tagged mutagenesis. Methods in Molecular Biology (Clifton, N.J.). 1149: 541-54. PMID 24818931 DOI: 10.1007/978-1-4939-0473-0_41  1
2014 Jeukens J, Boyle B, Kukavica-Ibrulj I, Ouellet MM, Aaron SD, Charette SJ, Fothergill JL, Tucker NP, Winstanley C, Levesque RC. Comparative genomics of isolates of a Pseudomonas aeruginosa epidemic strain associated with chronic lung infections of cystic fibrosis patients. Plos One. 9: e87611. PMID 24505294 DOI: 10.1371/journal.pone.0087611  1
2014 Yeung AT, Janot L, Pena OM, Neidig A, Kukavica-Ibrulj I, Hilchie A, Levesque RC, Overhage J, Hancock RE. Requirement of the Pseudomonas aeruginosa CbrA sensor kinase for full virulence in a murine acute lung infection model. Infection and Immunity. 82: 1256-67. PMID 24379284 DOI: 10.1128/IAI.01527-13  1
2013 Jeukens J, Boyle B, Bianconi I, Kukavica-Ibrulj I, Tümmler B, Bragonzi A, Levesque RC. Complete Genome Sequence of Persistent Cystic Fibrosis Isolate Pseudomonas aeruginosa Strain RP73. Genome Announcements. 1. PMID 23908295 DOI: 10.1128/genomeA.00568-13  0.64
2012 Breidenstein EB, Janot L, Strehmel J, Fernandez L, Taylor PK, Kukavica-Ibrulj I, Gellatly SL, Levesque RC, Overhage J, Hancock RE. The Lon protease is essential for full virulence in Pseudomonas aeruginosa. Plos One. 7: e49123. PMID 23145092 DOI: 10.1371/journal.pone.0049123  1
2012 Michaud FT, Havugimana PC, Duchesne C, Sanschagrin F, Bernier A, Lévesque RC, Garnier A. Cell culture tracking by multivariate analysis of raw LCMS data. Applied Biochemistry and Biotechnology. 167: 474-88. PMID 22562494 DOI: 10.1007/s12010-012-9661-4  1
2012 Boyle B, Fernandez L, Laroche J, Kukavica-Ibrulj I, Mendes CM, Hancock RW, Levesque RC. Complete genome sequences of three Pseudomonas aeruginosa isolates with phenotypes of polymyxin B adaptation and inducible resistance. Journal of Bacteriology. 194: 529-30. PMID 22207740 DOI: 10.1128/JB.06246-11  1
2012 Cusson M, Stoltz D, Lapointe R, Béliveau C, Nisole A, Volkoff AN, Drezen JM, Maaroufi H, Levesque RC. Genomics of Banchine Ichnoviruses: Insights into their relationship to Bracoviruses and Campoplegine Ichnoviruses Parasitoid Viruses: Symbionts and Pathogens. 79-87. DOI: 10.1016/B978-0-12-384858-1.00006-0  1
2011 Bianconi I, Milani A, Cigana C, Paroni M, Levesque RC, Bertoni G, Bragonzi A. Positive signature-tagged mutagenesis in Pseudomonas aeruginosa: tracking patho-adaptive mutations promoting airways chronic infection. Plos Pathogens. 7: e1001270. PMID 21304889 DOI: 10.1371/journal.ppat.1001270  1
2010 Cloutier I, Paradis-Bleau C, Giroux AM, Pigeon X, Arseneault M, Levesque RC, Auger M. Biophysical studies of the interactions between the phage varphiKZ gp144 lytic transglycosylase and model membranes. European Biophysics Journal : Ebj. 39: 263-76. PMID 19669132 DOI: 10.1007/s00249-009-0530-1  1
2009 Boulette ML, Baynham PJ, Jorth PA, Kukavica-Ibrulj I, Longoria A, Barrera K, Levesque RC, Whiteley M. Characterization of alanine catabolism in Pseudomonas aeruginosa and its importance for proliferation in vivo. Journal of Bacteriology. 191: 6329-34. PMID 19666712 DOI: 10.1128/JB.00817-09  1
2009 Paradis-Bleau C, Lloyd A, Sanschagrin F, Maaroufi H, Clarke T, Blewett A, Dowson C, Roper DI, Bugg TD, Levesque RC. Pseudomonas aeruginosa MurE amide ligase: enzyme kinetics and peptide inhibitor. The Biochemical Journal. 421: 263-72. PMID 19400768 DOI: 10.1042/BJ20081395  1
2009 Gooderham WJ, Gellatly SL, Sanschagrin F, McPhee JB, Bains M, Cosseau C, Levesque RC, Hancock RE. The sensor kinase PhoQ mediates virulence in Pseudomonas aeruginosa. Microbiology (Reading, England). 155: 699-711. PMID 19246741 DOI: 10.1099/mic.0.024554-0  1
2009 Winstanley C, Langille MG, Fothergill JL, Kukavica-Ibrulj I, Paradis-Bleau C, Sanschagrin F, Thomson NR, Winsor GL, Quail MA, Lennard N, Bignell A, Clarke L, Seeger K, Saunders D, Harris D, ... ... Levesque RC, et al. Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa. Genome Research. 19: 12-23. PMID 19047519 DOI: 10.1101/gr.086082.108  1
2008 Paradis-Bleau C, Lloyd A, Sanschagrin F, Clarke T, Blewett A, Bugg TD, Levesque RC. Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF. Bmc Biochemistry. 9: 33. PMID 19099588 DOI: 10.1186/1471-2091-9-33  1
2008 Kukavica-Ibrulj I, Levesque RC. Animal models of chronic lung infection with Pseudomonas aeruginosa: Useful tools for cystic fibrosis studies Laboratory Animals. 42: 389-412. PMID 18782827 DOI: 10.1258/la.2007.06014e  1
2008 Warren RL, Freeman JD, Levesque RC, Smailus DE, Flibotte S, Holt RA. Transcription of foreign DNA in Escherichia coli. Genome Research. 18: 1798-805. PMID 18701636 DOI: 10.1101/gr.080358.108  1
2008 Kukavica-Ibrulj I, Sanschagrin F, Peterson A, Whiteley M, Boyle B, Mackay J, Levesque RC. Functional genomics of PycR, a LysR family transcriptional regulator essential for maintenance of Pseudomonas aeruginosa in the rat lung. Microbiology (Reading, England). 154: 2106-18. PMID 18599838 DOI: 10.1099/mic.0.2007/011239-0  1
2008 Sanschagrin F, Kukavica-Ibrulj I, Levesque RC. Essential genes in the infection model of Pseudomonas aeruginosa PCR-based signature-tagged mutagenesis. Methods in Molecular Biology (Clifton, N.J.). 416: 61-82. PMID 18392961 DOI: 10.1007/978-1-59745-321-9_5  1
2008 Platt MD, Schurr MJ, Sauer K, Vazquez G, Kukavica-Ibrulj I, Potvin E, Levesque RC, Fedynak A, Brinkman FS, Schurr J, Hwang SH, Lau GW, Limbach PA, Rowe JJ, Lieberman MA, et al. Proteomic, microarray, and signature-tagged mutagenesis analyses of anaerobic Pseudomonas aeruginosa at pH 6.5, likely representing chronic, late-stage cystic fibrosis airway conditions. Journal of Bacteriology. 190: 2739-58. PMID 18203836 DOI: 10.1128/JB.01683-07  1
2008 Kukavica-Ibrulj I, Bragonzi A, Paroni M, Winstanley C, Sanschagrin F, O'Toole GA, Levesque RC. In vivo growth of Pseudomonas aeruginosa strains PAO1 and PA14 and the hypervirulent strain LESB58 in a rat model of chronic lung infection. Journal of Bacteriology. 190: 2804-13. PMID 18083816 DOI: 10.1128/JB.01572-07  1
2008 Lloyd AJ, Gilbey AM, Blewett AM, De Pascale G, El Zoeiby A, Levesque RC, Catherwood AC, Tomasz A, Bugg TD, Roper DI, Dowson CG. Characterization of tRNA-dependent peptide bond formation by MurM in the synthesis of Streptococcus pneumoniae peptidoglycan. The Journal of Biological Chemistry. 283: 6402-17. PMID 18077448 DOI: 10.1074/jbc.M708105200  1
2008 Potvin E, Sanschagrin F, Levesque RC. Sigma factors in Pseudomonas aeruginosa. Fems Microbiology Reviews. 32: 38-55. PMID 18070067 DOI: 10.1111/j.1574-6976.2007.00092.x  1
2008 Taha MO, Atallah N, Al-Bakri AG, Paradis-Bleau C, Zalloum H, Younis KS, Levesque RC. Discovery of new MurF inhibitors via pharmacophore modeling and QSAR analysis followed by in-silico screening. Bioorganic & Medicinal Chemistry. 16: 1218-35. PMID 17988876 DOI: 10.1016/j.bmc.2007.10.076  1
2007 Zhang S, McCormack FX, Levesque RC, O'Toole GA, Lau GW. The flagellum of Pseudomonas aeruginosa is required for resistance to clearance by surfactant protein A. Plos One. 2: e564. PMID 17593964 DOI: 10.1371/journal.pone.0000564  1
2007 Paradis-Bleau C, Cloutier I, Lemieux L, Sanschagrin F, Laroche J, Auger M, Garnier A, Levesque RC. Peptidoglycan lytic activity of the Pseudomonas aeruginosa phage phiKZ gp144 lytic transglycosylase. Fems Microbiology Letters. 266: 201-9. PMID 17233731 DOI: 10.1111/j.1574-6968.2006.00523.x  1
2007 Paradis-Bleau C, Beaumont M, Sanschagrin F, Voyer N, Levesque RC. Parallel solid synthesis of inhibitors of the essential cell division FtsZ enzyme as a new potential class of antibacterials. Bioorganic & Medicinal Chemistry. 15: 1330-40. PMID 17157508 DOI: 10.1016/j.bmc.2006.11.015  1
2006 Molina-López J, Sanschagrin F, Levesque RC. A peptide inhibitor of MurA UDP-N-acetylglucosamine enolpyruvyl transferase: the first committed step in peptidoglycan biosynthesis. Peptides. 27: 3115-21. PMID 17030076 DOI: 10.1016/j.peptides.2006.08.023  1
2006 Morin S, Levesque RC, Gagné SM. 1H, 13C, and 15N backbone resonance assignments for PSE-4, a 29.5 kDa class A beta-lactamase from Pseudomonas aeruginosa. Journal of Biomolecular Nmr. 36: 11. PMID 16642403 DOI: 10.1007/s10858-005-5343-7  1
2006 Paradis-Bleau C, Beaumont M, Boudreault L, Lloyd A, Sanschagrin F, Bugg TD, Levesque RC. Selection of peptide inhibitors against the Pseudomonas aeruginosa MurD cell wall enzyme. Peptides. 27: 1693-700. PMID 16517013 DOI: 10.1016/j.peptides.2006.01.017  1
2006 Levesque RC. In vivo functional genomics of pseudomonas: PCR-based signature-tagged mutagenesis Pseudomonas. 4: 99-120. DOI: 10.1007/0-387-28881-3_4  1
2006 Ramos JL, Levesque RC. Preface Pseudomonas. 4: v-vi. DOI: 10.1007/0-387-28881-3  1
2005 Zhang S, Chen Y, Potvin E, Sanschagrin F, Levesque RC, McCormack FX, Lau GW. Comparative signature-tagged mutagenesis identifies Pseudomonas factors conferring resistance to the pulmonary collectin SP-A. Plos Pathogens. 1: 259-68. PMID 16322768 DOI: 10.1371/journal.ppat.0010031  1
2005 Paradis-Bleau C, Sanschagrin F, Levesque RC. Peptide inhibitors of the essential cell division protein FtsA. Protein Engineering, Design & Selection : Peds. 18: 85-91. PMID 15790573 DOI: 10.1093/protein/gzi008  1
2005 Sanschagrin F, Levesque RC. A specific peptide inhibitor of the class B metallo-beta-lactamase L-1 from Stenotrophomonas maltophilia identified using phage display. The Journal of Antimicrobial Chemotherapy. 55: 252-5. PMID 15659541 DOI: 10.1093/jac/dkh550  1
2004 Maynard C, Bekal S, Sanschagrin F, Levesque RC, Brousseau R, Masson L, Larivière S, Harel J. Heterogeneity among virulence and antimicrobial resistance gene profiles of extraintestinal Escherichia coli isolates of animal and human origin. Journal of Clinical Microbiology. 42: 5444-52. PMID 15583263 DOI: 10.1128/JCM.42.12.5444-5452.2004  1
2004 Savard PY, Sosa-Peinado A, Levesque RC, Makinen MW, Gagné SM. 1H, 13C and 15N backbone resonance assignments for TEM-1, a 28.9 kDa beta-lactamase from E. coli. Journal of Biomolecular Nmr. 29: 433-4. PMID 15213455 DOI: 10.1023/B:JNMR.0000032503.96942.68  1
2004 Paradis-Bleau C, Sanschagrin F, Levesque RC. Identification of Pseudomonas aeruginosa FtsZ peptide inhibitors as a tool for development of novel antimicrobials. The Journal of Antimicrobial Chemotherapy. 54: 278-80. PMID 15190020 DOI: 10.1093/jac/dkh318  1
2004 Lehoux DE, Sanschagrin F, Kukavica-Ibrulj I, Potvin E, Levesque RC. Identification of novel pathogenicity genes by PCR signature-tagged mutagenesis and related technologies. Methods in Molecular Biology (Clifton, N.J.). 266: 289-304. PMID 15148424 DOI: 10.1385/1-59259-763-7:289  1
2003 Potvin E, Lehoux DE, Kukavica-Ibrulj I, Richard KL, Sanschagrin F, Lau GW, Levesque RC. In vivo functional genomics of Pseudomonas aeruginosa for high-throughput screening of new virulence factors and antibacterial targets. Environmental Microbiology. 5: 1294-308. PMID 14641575 DOI: 10.1046/j.1462-2920.2003.00542.x  1
2003 Maynard C, Fairbrother JM, Bekal S, Sanschagrin F, Levesque RC, Brousseau R, Masson L, Larivière S, Harel J. Antimicrobial resistance genes in enterotoxigenic Escherichia coli O149:K91 isolates obtained over a 23-year period from pigs. Antimicrobial Agents and Chemotherapy. 47: 3214-21. PMID 14506033 DOI: 10.1128/AAC.47.10.3214-3221.2003  1
2003 El Zoeiby A, Beaumont M, Dubuc E, Sanschagrin F, Voyer N, Levesque RC. Combinatorial enzymatic assay for the screening of a new class of bacterial cell wall inhibitors. Bioorganic & Medicinal Chemistry. 11: 1583-92. PMID 12628682 DOI: 10.1016/S0968-0896(02)00447-9  1
2003 El Zoeiby A, Sanschagrin F, Darveau A, Brisson JR, Levesque RC. Identification of novel inhibitors of Pseudomonas aeruginosa MurC enzyme derived from phage-displayed peptide libraries. The Journal of Antimicrobial Chemotherapy. 51: 531-43. PMID 12615853 DOI: 10.1093/jac/dkg010  1
2003 El Zoeiby A, Sanschagrin F, Levesque RC. Structure and function of the Mur enzymes: development of novel inhibitors. Molecular Microbiology. 47: 1-12. PMID 12492849 DOI: 10.1046/j.1365-2958.2003.03289.x  1
2002 Lehoux DE, Levesque RC. PCR screening in signature-tagged mutagenesis of essential genes. Methods in Molecular Biology (Clifton, N.J.). 192: 225-34. PMID 12494654 DOI: 10.1385/1-59259-177-9:225  1
2002 Izallalen M, Levesque RC, Perret X, Broughton WJ, Antoun H. Broad-host-range mobilizable suicide vectors for promoter trapping in gram-negative bacteria. Biotechniques. 33: 1038-40, 1042-3. PMID 12449381  1
2002 Beatson SA, Whitchurch CB, Sargent JL, Levesque RC, Mattick JS. Differential regulation of twitching motility and elastase production by Vfr in Pseudomonas aeruginosa. Journal of Bacteriology. 184: 3605-13. PMID 12057955 DOI: 10.1128/JB.184.13.3605-3613.2002  1
2002 Lehoux DE, Sanschagrin F, Levesque RC. Identification of in vivo essential genes from Pseudomonas aeruginosa by PCR-based signature-tagged mutagenesis. Fems Microbiology Letters. 210: 73-80. PMID 12023080 DOI: 10.1016/S0378-1097(02)00597-9  1
2002 Lehoux DE, Levesque RC. Polymerase chain reaction-based signature-tagged mutagenesis. Methods in Molecular Biology (Clifton, N.J.). 182: 127-37. PMID 11768960  1
2001 Lehoux DE, Sanschagrin F, Levesque RC. Discovering essential and infection-related genes. Current Opinion in Microbiology. 4: 515-9. PMID 11587926 DOI: 10.1016/S1369-5274(00)00244-7  1
2001 El Zoeiby A, Sanschagrin F, Havugimana PC, Garnier A, Levesque RC. In vitro reconstruction of the biosynthetic pathway of peptidoglycan cytoplasmic precursor in Pseudomonas aeruginosa. Fems Microbiology Letters. 201: 229-35. PMID 11470366 DOI: 10.1016/S0378-1097(01)00268-3  1
2001 Lim D, Sanschagrin F, Passmore L, De Castro L, Levesque RC, Strynadka NC. Insights into the molecular basis for the carbenicillinase activity of PSE-4 beta-lactamase from crystallographic and kinetic studies. Biochemistry. 40: 395-402. PMID 11148033 DOI: 10.1021/bi001653v  1
2000 Lehoux DE, Levesque RC. Detection of genes essential in specific niches by signature-tagged mutagenesis. Current Opinion in Biotechnology. 11: 434-9. PMID 11024359 DOI: 10.1016/S0958-1669(00)00124-5  1
2000 Lehoux DE, Sanschagrin F, Levesque RC. Genomics of the 35-kb pvd locus and analysis of novel pvdIJK genes implicated in pyoverdine biosynthesis in Pseudomonas aeruginosa. Fems Microbiology Letters. 190: 141-6. PMID 10981704 DOI: 10.1016/S0378-1097(00)00314-1  1
2000 Therrien C, Levesque RC. Molecular basis of antibiotic resistance and β-lactamase inhibition by mechanism-based inactivators: Perspectives and future directions Fems Microbiology Reviews. 24: 251-262. PMID 10841972 DOI: 10.1016/S0168-6445(99)00039-X  1
2000 Savoie A, Sanschagrin F, Palzkill T, Voyer N, Levesque RC. Structure-function analysis of alpha-helix H4 using PSE-4 as a model enzyme representative of class A beta-lactamases. Protein Engineering. 13: 267-74. PMID 10810158  1
2000 Sanschagrin F, Thériault E, Sabbagh Y, Voyer N, Levesque RC. Combinatorial biochemistry and shuffling of TEM, SHV and Streptomyces albus omega loops in PSE-4 class A beta-lactamase. The Journal of Antimicrobial Chemotherapy. 45: 517-20. PMID 10747830  1
2000 Therrien C, Kotra LP, Sanschagrin F, Mobashery S, Levesque RC. Evaluation of inhibition of the carbenicillin-hydrolyzing beta-lactamase PSE-4 by the clinically used mechanism-based inhibitors. Febs Letters. 470: 285-92. PMID 10745083 DOI: 10.1016/S0014-5793(00)01342-9  1
2000 Handfield M, Lehoux DE, Sanschagrin F, Mahan MJ, Woods DE, Levesque RC. In vivo-induced genes in Pseudomonas aeruginosa. Infection and Immunity. 68: 2359-62. PMID 10722644 DOI: 10.1128/IAI.68.4.2359-2362.2000  1
2000 El Zoeiby A, Sanschagrin F, Lamoureux J, Darveau A, Levesque RC. Cloning, over-expression and purification of Pseudomonas aeruginosa murC encoding uridine diphosphate N-acetylmuramate: L-alanine ligase. Fems Microbiology Letters. 183: 281-8. PMID 10675598 DOI: 10.1016/S0378-1097(00)00003-3  1
1999 Lehoux DE, Sanschagrin F, Levesque RC. Defined oligonucleotide tag pools and PCR screening in signature-tagged mutagenesis of essential genes from bacteria. Biotechniques. 26: 473-8, 480. PMID 10090989  1
1999 Handfield M, Levesque RC. Strategies for isolation of in vivo expressed genes from bacteria Fems Microbiology Reviews. 23: 69-91. PMID 10077854 DOI: 10.1016/S0168-6445(98)00033-3  1
1999 Trépanier S, Knox JR, Clairoux N, Sanschagrin F, Levesque RC, Huletsky A. Structure-function studies of Ser-289 in the class C beta-lactamase from Enterobacter cloacae P99. Antimicrobial Agents and Chemotherapy. 43: 543-8. PMID 10049265  1
1998 Therrien C, Sanschagrin F, Palzkill T, Levesque RC. Roles of amino acids 161 to 179 in the PSE-4 omega loop in substrate specificity and in resistance to ceftazidime. Antimicrobial Agents and Chemotherapy. 42: 2576-83. PMID 9756758  1
1998 Sabbagh Y, Thériault E, Sanschagrin F, Voyer N, Palzkill T, Levesque RC. Characterization of a PSE-4 mutant with different properties in relation to penicillanic acid sulfones: Importance of residues 216 to 218 in class A β-lactamases Antimicrobial Agents and Chemotherapy. 42: 2319-2325. PMID 9736556  1
1998 Dewar K, Sabbagh L, Cardinal G, Veilleux F, Sanschagrin F, Birren B, Levesque RC. Pseudomonas aeruginosa PAO1 bacterial artificial chromosomes: strategies for mapping, screening, and sequencing 100 kb loci of the 5.9 Mb genome Microbial &Amp; Comparative Genomics. 3: 105-117. PMID 9697095  1
1998 Sanschagrin F, Bejaoui N, Levesque RC. Structure of CARB-4 and AER-1 carbenicillin hydrolyzing β-lactamases Antimicrobial Agents and Chemotherapy. 42: 1966-1972. PMID 9687391  1
1998 Handfield M, Schweizer HP, Mahan MJ, Sanschagrin F, Hoang T, Levesque RC. ASD-GFP vectors for in vivo expression technology in Pseudomonas aeruginosa and other gram-negative bacteria Biotechniques. 24: 261-264. PMID 9494727 DOI: 10.2144/98242st02  1
1996 Gagnon S, Bourbeau D, Levesque RC. Secondary structures and features of the 18S, 5.8S and 26S ribosomal RNAs from the Apicomplexan parasite Toxoplasma gondii Gene. 173: 129-135. PMID 8964489 DOI: 10.1016/0378-1119(96)00215-6  1
1996 Gagnon S, Morency MJ, Bourbeau D, Levesque RC. Toxoplasma gondii: Structure and characterization of the 26S ribosomal RNA and peptidyl transferase domain Experimental Parasitology. 83: 346-351. PMID 8823251 DOI: 10.1006/expr.1996.0082  1
1995 Sanschagrin F, Couture F, Levesque RC. Primary structure of OXA-3 and phylogeny of oxacillin-hydrolyzing class D β-lactamases Antimicrobial Agents and Chemotherapy. 39: 887-893. PMID 7785990  1
1995 Bourque SN, Valero JR, Lavoie MC, Levesque RC. Comparative analysis of the 16S to 23S ribosomal intergenic spacer sequences of Bacillus thuringiensis strains and subspecies and of closely related species Applied and Environmental Microbiology. 61: 1623-1626. PMID 7538281  1
1993 Bourque SN, Valero JR, Mercier J, Lavoie MC, Levesque RC. Multiplex polymerase chain reaction for detection and differentiation of the microbial insecticide Bacillus thuringiensis Applied and Environmental Microbiology. 59: 523-527. PMID 8434916  1
1993 Guay JM, Dubois D, Morency MJ, Gagnon S, Mercier J, Levesque RC. Detection of the pathogenic parasite Toxoplasma gondii by specific amplification of ribosomal sequences using comultiplex polymerase chain reaction Journal of Clinical Microbiology. 31: 203-207. PMID 8432803  1
1993 Huletsky A, Knox JR, Levesque RC. Role of Ser-238 and Lys-240 in the hydrolysis of third-generation cephalosporins by SHV-type β-lactamases probed by site-directed mutagenesis and three-dimensional modeling Journal of Biological Chemistry. 268: 3690-3697. PMID 8429044  1
1993 Gagnon S, Levesque RC, Sogin ML, Gajadhar AA. Molecular cloning, complete sequence of the small subunit ribosomal RNA coding region and phylogeny of Toxoplasma gondii Molecular and Biochemical Parasitology. 60: 145-148. PMID 8366888 DOI: 10.1016/0166-6851(93)90037-X  1
1993 Simon L, Levesque RC, Lalonde M. Identification of endomycorrhizal fungi colonizing roots by fluorescent single-strand conformation polymorphism-polymerase chain reaction Applied and Environmental Microbiology. 59: 4211-4215. PMID 8285712  1
1993 Bergeron J, Beaulieu C, Levesque RC, Kondorosi A, Dion P. Homology between the genes of octopine catabolism of Rhizobium meliloti A3 and corresponding genes from the Ti plasmid Canadian Journal of Microbiology. 39: 1041-1050.  1
1992 Maclean IW, Slaney L, Juteau JM, Levesque RC, Albritton WL, Ronald AR. Identification of a ROB-1 β-lactamase in Haemophilus ducreyi Antimicrobial Agents and Chemotherapy. 36: 467-469. PMID 1605612  1
1992 Guay JM, Huot A, Gagnon S, Tremblay A, Levesque RC. Physical and genetic mapping of cloned ribosomal DNA from Toxoplasma gondii: primary and secondary structure of the 5S gene Gene. 114: 165-171. PMID 1601300 DOI: 10.1016/0378-1119(92)90570-F  1
1992 Couture F, Lachapelle J, Levesque RC. Phylogeny of LCR-1 and OXA-5 with class a and class D β-lactamases Molecular Microbiology. 6: 1693-1705. PMID 1495394  1
1992 Juteau JM, Billings E, Knox JR, Levesque RC. Site-saturation mutagenesis and three-dimensional modelling of rob-1 define a substrate binding role of ser 130 in class a β-lactamases Protein Engineering, Design and Selection. 5: 693-701. PMID 1480622 DOI: 10.1093/protein/5.7.693  1
1992 Gagnon G, Vadeboncoeur C, Levesque RC, Frenette M. Cloning, sequencing and expression in Escherichia coli of the ptsI gene encoding enzyme I of the phosphoenolpyruvate:sugar phosphotransferase transport system from Streptococcus salivarius Gene. 121: 71-78. PMID 1427100 DOI: 10.1016/0378-1119(92)90163-J  1
1991 Ambler RP, Coulson AFW, Frere JM, Ghuysen JM, Joris B, Forsman M, Levesque RC, Tiraby G, Waley SG. A standard numbering scheme for the class A β-lactamases [1] Biochemical Journal. 276: 269-270. PMID 2039479  1
1991 Juteau JM, Sirois M, Medeiros AA, Levesque RC. Molecular distribution of ROB-1 β-lactamase in Actinobacillus pleuropneumoniae Antimicrobial Agents and Chemotherapy. 35: 1397-1402. PMID 1929299  1
1991 Sirois M, Lemire EG, Levesque RC. Construction of a DNA probe and detection of Actinobacillus pleuropneumoniae by using polymerase chain reaction Journal of Clinical Microbiology. 29: 1183-1187. PMID 1864937  1
1991 Vezina G, Levesque RC. Molecular characterization of the class II multiresistance transposable element Tn1403 from Pseudomonas aeruginosa Antimicrobial Agents and Chemotherapy. 35: 313-321. PMID 1850969  1
1991 Lachapelle J, Dufresne J, Levesque RC. Characterization of the blaCARB-3 gene encoding the carbenicillinase-3 β-lactamase of Pseudomonas aeruginosa Gene. 102: 7-12. PMID 1650733 DOI: 10.1016/0378-1119(91)90530-O  1
1991 Juteau JM, Cote S, Levesque RC. Systematic site-saturation mutagenesis of ROB-1 β-lactamase: Efficiency of T4 polymerase and oligonucleotide synthesis Biotechniques. 11: 460-462.  1
1990 Boissinot M, Levesque RC. Nucleotide sequence of the PSE-4 carbenicillinase gene and correlations with the Staphylococcus aureus PC1 β-lactamase crystal structure Journal of Biological Chemistry. 265: 1225-1230. PMID 2295609  1
1990 Huletsky A, Couture F, Levesque RC. Nucleotide sequence and phylogeny of SHV-2 β-lactamase Antimicrobial Agents and Chemotherapy. 34: 1725-1732. PMID 2285285  1
1990 Mercier J, Levesque RC. Cloning of SHV-2, OHIO-1, and OXA-6 β-lactamases and cloning and sequencing of SHV-1 β-lactamase Antimicrobial Agents and Chemotherapy. 34: 1577-1583. PMID 2221867  1
1990 Juteau JM, Levesque RC. Sequence analysis and evolutionary perspectives of ROB-1 β-lactamase Antimicrobial Agents and Chemotherapy. 34: 1354-1359. PMID 2201253  1
1990 Mercier J, Lachapelle J, Couture F, Lafond M, Vezina G, Boissinot M, Levesque RC. Structural and functional characterization of tnpI, a recombinase locus in Tn21 and related β-lactamase transposons Journal of Bacteriology. 172: 3745-3757. PMID 2163386  1
1989 Boissinot M, Huot A, Mercier J, Levesque RC. Development of gene probes and evolutionary relationships of the PSE-4 bla gene to plasmid-mediated β-lactamases of gram-negative bacteria Molecular and Cellular Probes. 3: 179-188. PMID 2788807 DOI: 10.1016/0890-8508(89)90028-5  1
1989 Lafond M, Couture F, Vezina G, Levesque RC. Evolutionary perspectives on multiresistance β-lactamase transposons Journal of Bacteriology. 171: 6423-6429. PMID 2556363  1
1989 Trias J, Dufresne J, Levesque RC, Nikaido H. Decreased outer membrane permeability in imipenem-resistant mutants of Pseudomonas aeruginosa Antimicrobial Agents and Chemotherapy. 33: 1201-1206. PMID 2508541  1
1989 Werquin M, Ackermann HW, Levesque RC. Characteristics and comparative study of five Rhizobium meliloti bacteriophages Current Microbiology. 18: 307-311. DOI: 10.1007/BF01575946  1
1988 Dufresne J, Vezina G, Levesque RC. Cloning and expression of the imipenem-hydrolyzing β-lactamase operon from Pseudomonas maltophilia in Escherichia coli Antimicrobial Agents and Chemotherapy. 32: 819-826. PMID 3046482  1
1988 Dufresne J, Vezina G, Levesque RC. Molecular cloning and expression of the imipenem-hydrolyzing β-lactamase gene from pseudomonas maltophilia in escherichia coli Clinical Infectious Diseases. 10: 806-817. PMID 2847278 DOI: 10.1093/clinids/10.4.806  1
1988 Levesque RC, Jacoby GA. Molecular structure and interrelationships of multiresistance β-lactamase transposons Plasmid. 19: 21-29. PMID 2840678 DOI: 10.1016/0147-619X(88)90059-5  1
1987 Boissinot M, Mercier J, Levesque RC. Development of natural and synthetic DNA probes for OXA-2 and TEM-1 β-lactamases Antimicrobial Agents and Chemotherapy. 31: 728-734. PMID 3038006  1
1987 Levesque RC, Medeiros AA, Jacoby GA. Molecular cloning and DNA homology of plasmid-mediated β-lactamase genes Mgg Molecular &Amp; General Genetics. 206: 252-258. PMID 3035334 DOI: 10.1007/BF00333581  1
1987 Morin CJ, Patel PC, Levesque RC, Letarte R. Monoclonal antibodies to TEM-1 plasmid-mediated beta-lactamase. Antimicrobial Agents and Chemotherapy. 31: 1761-7. PMID 2449122  1
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