Hanne Ostergaard - Publications

University of Alberta, Edmonton, Alberta, Canada 
Immunology, Microbiology Biology

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Cheung SM, Ostergaard HL. Pyk2 Controls Integrin-Dependent CTL Migration through Regulation of De-Adhesion. Journal of Immunology (Baltimore, Md. : 1950). PMID 27456486 DOI: 10.4049/jimmunol.1501505  1
2013 St-Pierre J, Ostergaard HL. A role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation. Plos One. 8: e71531. PMID 23936270 DOI: 10.1371/journal.pone.0071531  1
2013 Lipinski T, Fitieh A, St Pierre J, Ostergaard HL, Bundle DR, Touret N. Enhanced immunogenicity of a tricomponent mannan tetanus toxoid conjugate vaccine targeted to dendritic cells via Dectin-1 by incorporating β-glucan. Journal of Immunology (Baltimore, Md. : 1950). 190: 4116-28. PMID 23514738 DOI: 10.4049/jimmunol.1202937  1
2011 Robertson LK, Ostergaard HL. Paxillin associates with the microtubule cytoskeleton and the immunological synapse of CTL through its leucine-aspartic acid domains and contributes to microtubule organizing center reorientation. Journal of Immunology (Baltimore, Md. : 1950). 187: 5824-33. PMID 22043013 DOI: 10.4049/jimmunol.1003690  1
2011 St-Pierre J, Lysechko TL, Ostergaard HL. Hypophosphorylated and inactive Pyk2 associates with paxillin at the microtubule organizing center in hematopoietic cells. Cellular Signalling. 23: 718-30. PMID 21195757 DOI: 10.1016/j.cellsig.2010.12.006  1
2010 Lysechko TL, Cheung SM, Ostergaard HL. Regulation of the tyrosine kinase Pyk2 by calcium is through production of reactive oxygen species in cytotoxic T lymphocytes. The Journal of Biological Chemistry. 285: 31174-84. PMID 20688918 DOI: 10.1074/jbc.M110.118265  1
2010 He JS, Gong DE, Ostergaard HL. Stored Fas ligand, a mediator of rapid CTL-mediated killing, has a lower threshold for response than degranulation or newly synthesized Fas ligand. Journal of Immunology (Baltimore, Md. : 1950). 184: 555-63. PMID 19949069 DOI: 10.4049/jimmunol.0902465  1
2010 Ferguson BV, Ostergaard HL. CD45 regulates thymocyte survival during development in fetal thymic organ culture. Immunobiology. 215: 458-65. PMID 19765855 DOI: 10.1016/j.imbio.2009.08.005  1
2007 He JS, Ostergaard HL. CTLs contain and use intracellular stores of FasL distinct from cytolytic granules. Journal of Immunology (Baltimore, Md. : 1950). 179: 2339-48. PMID 17675495  1
2007 Ostergaard HL. PKC and Erk in CTL degranulation Modern Aspects of Immunobiology. 21: 7.  1
2006 Puente LG, He JS, Ostergaard HL. A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: Plasticity in PKC regulation of ERK. European Journal of Immunology. 36: 1009-18. PMID 16552708 DOI: 10.1002/eji.200535277  1
2005 Robertson LK, Mireau LR, Ostergaard HL. A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation. Journal of Immunology (Baltimore, Md. : 1950). 175: 8138-45. PMID 16339552  1
2005 Shen A, Puente LG, Ostergaard HL. Tyrosine kinase activity and remodelling of the actin cytoskeleton are co-temporally required for degranulation by cytotoxic T lymphocytes. Immunology. 116: 276-86. PMID 16162276 DOI: 10.1111/j.1365-2567.2005.02222.x  1
2005 Lysechko TL, Ostergaard HL. Differential Src family kinase activity requirements for CD3 zeta phosphorylation/ZAP70 recruitment and CD3 epsilon phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). 174: 7807-14. PMID 15944285 DOI: 10.4049/jimmunol.174.12.7807  1
2005 Ostergaard HL, Lysechko TL. Focal adhesion kinase-related protein tyrosine kinase Pyk2 in T-cell activation and function. Immunologic Research. 31: 267-82. PMID 15888917 DOI: 10.1385/IR:31:3:267  1
2005 Puente LG, Mireau LR, Lysechko TL, Ostergaard HL. Phosphatidylinositol-3-kinase regulates PKCtheta activity in cytotoxic T cells. Molecular Immunology. 42: 1177-84. PMID 15829307 DOI: 10.1016/j.molimm.2004.11.012  1
2005 Chun J, Chau AS, Maingat FG, Edmonds SD, Ostergaard HL, Shibuya EK. Phosphorylation of Cdc25C by pp90Rsk contributes to a G2 cell cycle arrest in Xenopus cycling egg extracts. Cell Cycle (Georgetown, Tex.). 4: 148-54. PMID 15539959  1
2003 Puente LG, Ostergaard HL. Beta 1/beta 3 integrin ligation is uncoupled from ERK1/ERK2 activation in cytotoxic T lymphocytes. Journal of Leukocyte Biology. 73: 391-8. PMID 12629153 DOI: 10.1189/jlb.0402199  1
2002 Edmonds SD, Ostergaard HL. Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 169: 5036-42. PMID 12391219  1
2002 Baldwin TA, Ostergaard HL. The protein-tyrosine phosphatase CD45 reaches the cell surface via golgi-dependent and -independent pathways. The Journal of Biological Chemistry. 277: 50333-40. PMID 12386161 DOI: 10.1074/jbc.M209075200  1
2002 Wang C, Hayashi H, Harrison R, Chiu B, Chan JR, Ostergaard HL, Inman RD, Jongstra J, Cybulsky MI, Jongstra-Bilen J. Modulation of Mac-1 (CD11b/CD18)-mediated adhesion by the leukocyte-specific protein 1 is key to its role in neutrophil polarization and chemotaxis. Journal of Immunology (Baltimore, Md. : 1950). 169: 415-23. PMID 12077272 DOI: 10.4049/jimmunol.169.1.415  1
2001 Baldwin TA, Ostergaard HL. Developmentally regulated changes in glucosidase II association with, and carbohydrate content of, the protein tyrosine phosphatase CD45. Journal of Immunology (Baltimore, Md. : 1950). 167: 3829-35. PMID 11564800  1
2000 Puente LG, Stone JC, Ostergaard HL. Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins. Journal of Immunology (Baltimore, Md. : 1950). 165: 6865-71. PMID 11120810  1
2000 Dower NA, Stang SL, Bottorff DA, Ebinu JO, Dickie P, Ostergaard HL, Stone JC. RasGRP is essential for mouse thymocyte differentiation and TCR signaling Nature Immunology. 1: 317-321. PMID 11017103  1
2000 Baldwin TA, Gogela-Spehar M, Ostergaard HL. Specific isoforms of the resident endoplasmic reticulum protein glucosidase II associate with the CD45 protein-tyrosine phosphatase via a lectin-like interaction. The Journal of Biological Chemistry. 275: 32071-6. PMID 10921916 DOI: 10.1074/jbc.M003088200  1
2000 Arendt CW, Ostergaard HL. Two distinct domains of the beta-subunit of glucosidase II interact with the catalytic alpha-subunit. Glycobiology. 10: 487-92. PMID 10764837 DOI: 10.1093/glycob/10.5.487  1
1999 Arendt CW, Dawicki W, Ostergaard HL. Alternative splicing of transcripts encoding the alpha- and beta-subunits of mouse glucosidase II in T lymphocytes. Glycobiology. 9: 277-83. PMID 10024665 DOI: 10.1093/glycob/9.3.277  1
1998 Berg NN, Puente LG, Dawicki W, Ostergaard HL. Sustained TCR signaling is required for mitogen-activated protein kinase activation and degranulation by cytotoxic T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 161: 2919-24. PMID 9743353  1
1998 Ostergaard HL, Lou O, Arendt CW, Berg NN. Paxillin phosphorylation and association with Lck and Pyk2 in anti-CD3- or anti-CD45-stimulated T cells. The Journal of Biological Chemistry. 273: 5692-6. PMID 9488700 DOI: 10.1074/jbc.273.10.5692  1
1997 Berg NN, Ostergaard HL. T Cell Receptor Engagement Induces Tyrosine Phosphorylation of FAK and Pyk2 and their Association with Lck Journal of Immunology. 159: 1753-1757. PMID 9257837  1
1997 Arendt CW, Ostergaard HL. Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II. The Journal of Biological Chemistry. 272: 13117-25. PMID 9148925 DOI: 10.1074/jbc.272.20.13117  1
1997 Ma EA, Lou O, Berg NN, Ostergaard HL. Cytotoxic T lymphocytes express a β3 integrin which can induce the phosphorylation of focal adhesion kinase and the related PYK-2 European Journal of Immunology. 27: 329-335. PMID 9022036 DOI: 10.1002/eji.1830270147  1
1997 Arendt DW, Ostergaard HL. The interaction between the A and subunits of glucosidase II is mediated by the amino terminus of the subunit protein Faseb Journal. 11: A1243.  1
1997 Dawson JF, Ostergaard HL, Klix H, Boland MP, Holmes CFB. Evidence for reversible tyrosine protein phosphorylation in the okadaic acid-producing marine dinoflagellate Prorocentrum lima Journal of Eukaryotic Microbiology. 44: 89-95.  1
1996 Atkinson EA, Ostergaard H, Kane K, Pinkoski MJ, Caputo A, Olszowy MW, Bleackley RC. A physical interaction between the cell death protein Fas and the tyrosine kinase p59fynT. The Journal of Biological Chemistry. 271: 5968-71. PMID 8626376  1
1995 Ostergaard HL, Ma EA. Fibronectin induces phosphorylation of a 120-kDa protein and synergizes with the T cell receptor to activate cytotoxic T cell clones European Journal of Immunology. 25: 252-256. PMID 7843239 DOI: 10.1002/eji.1830250141  1
1995 Arendt CW, Ostergaard HL. CD45 protein-tyrosine phosphatase is specifically associated with a 116-kDa tyrosine-phosphorylated glycoprotein. The Journal of Biological Chemistry. 270: 2313-9. PMID 7836464  1
1995 Mossman K, Ostergaard H, Upton C, McFadden G. Myxoma virus and shope fibroma virus encode dual-specificity tyrosine/serine phosphatases which are essential for virus viability Virology. 206: 572-582. PMID 7831813 DOI: 10.1016/S0042-6822(95)80074-3  1
1995 Berg NN, Ostergaard HL. Characterization of intercellular adhesion molecule-1 (ICAM-1)-augmented degranulation by cytotoxic T cells ICAM-1 and anti-CD3 must be co-localized for optimal adhesion and stimulation Journal of Immunology. 155: 1694-1702. PMID 7636228  1
1995 Arendt CW, Hsi G, Ostergaard HL. Immobilized antibodies to CD45 induce rapid morphologic changes and increased tyrosine phosphorylation of p56lck-associated proteins in T cells. Journal of Immunology (Baltimore, Md. : 1950). 155: 5095-103. PMID 7594518  1
1992 Trowbridge IS, Johnson P, Ostergaard H, Hole N. Structure and function of CD45: A leukocyte-specific protein tyrosine phosphatase Advances in Experimental Medicine and Biology. 323: 29-38. PMID 1485564  1
1992 Trowbridge IS, Johnson P, Ostergaard H, Hole N. Regulation and structure-function relationship of CD45 Biochemical Society Transactions. 20: 174-178. PMID 1386037  1
1992 Johnson P, Ostergaard HL, Wasden C, Trowbridge IS. Mutational analysis of CD45. A leukocyte-specific protein tyrosine phosphatase Journal of Biological Chemistry. 267: 8035-8041. PMID 1314815  1
1991 Taetle R, Ostergaard H, Smedsrud M, Trowbridge I. Regulation of CD45 expression in human leukemia cells Leukemia. 5: 309-314. PMID 1851241  1
1991 Trowbridge IS, Ostergaard HL, Johnson P. CD45: a leukocyte-specific member of the protein tyrosine phosphatase family Bba - Molecular Cell Research. 1095: 46-56. PMID 1834176 DOI: 10.1016/0167-4889(91)90043-W  1
1991 Ostergaard HL, Trowbridge IS. Negative regulation of CD45 protein tyrosine phosphatase activity by ionomycin in T cells Science. 253: 1423-1425. PMID 1654595  1
1990 Ostergaard HL, Trowbridge IS. Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck Journal of Experimental Medicine. 172: 347-350. PMID 2141630  1
1989 Ostergaard HL, Shackelford DA, Hurley TR, Johnson P, Hyman R, Sefton BM, Trowbridge IS. Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines. Proceedings of the National Academy of Sciences of the United States of America. 86: 8959-63. PMID 2530588 DOI: 10.1073/pnas.86.22.8959  1
1989 Ostergaard HL, Clark WR. Evidence for multiple lytic pathways used by cytotoxic T lymphocytes Journal of Immunology. 143: 2120-2126. PMID 2506276  1
1988 Clark W, Ostergaard H, Gorman K, Torbett B. Molecular mechanisms of CTL-mediated lysis: a cellular perspective Immunological Reviews. 103: 37-51. PMID 3292395  1
1988 Ostergaard H, Gorman K, Clark WR. Cloned cytotoxic T lymphocyte target cells fail to induce early activation events in effector cytotoxic T lymphocytes Cellular Immunology. 114: 188-197. PMID 3259474 DOI: 10.1016/0008-8749(88)90265-1  1
1987 Ostergaard H, Clark WR. The role of Ca2+ in activation of mature cytotoxic T lymphocytes for lysis Journal of Immunology. 139: 3573-3579. PMID 3500223  1
1987 Blakely A, Gorman K, Ostergaard H, Svoboda K, Liu CC, Young JD, Clark WR. Resistance of cloned cytotoxic T lymphocytes to cell-mediated cytotoxicity. The Journal of Experimental Medicine. 166: 1070-83. PMID 3498787  1
1987 Ostergaard HL, Kane KP, Mescher MF, Clark WR. Cytotoxic T lymphocyte mediated lysis without release of serine esterase Nature. 330: 71-72. PMID 3118212  1
1986 Dewes H, Ostergaard HL, Simpson L. Impaired drug uptake in methotrexate resistant Crithidia fasciculata without changes in dihydrofolate reductase activity or gene amplification Molecular and Biochemical Parasitology. 19: 149-161. PMID 3724795 DOI: 10.1016/0166-6851(86)90120-9  1
1985 Bonavida B, Ostergaard H, Katz J. Mechanism of T-dependent cytotoxicity: role of papain-sensitive non class I MHC target molecules and expression of target antigen for cytotoxicity Advances in Experimental Medicine and Biology. 184: 415-428. PMID 2994412 DOI: 10.1007/978-1-4684-8326-0_28  1
1984 Ostergaard H, Bonavida B. Mechanism of oxidative dependent cellular cytotoxicity (ODCC): Two signals involved in the expression of cytotoxicity by the target cell Federation Proceedings. 43.  1
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