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Edward P. Browne, Ph.D. - Publications

Affiliations: 
2003 Princeton University, Princeton, NJ 
Area:
Molecular Biology
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29/62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Fenton AD, Archin N, Turner A-M, Joseph S, Moeser M, Margolis DM, Browne EP. A novel high-throughput microwell outgrowth assay for HIV-infected cells. Journal of Virology. e0179823. PMID 38376258 DOI: 10.1128/jvi.01798-23  0.337
2023 Cortés-Llanos B, Jain V, Cooper-Volkheimer A, Browne EP, Murdoch DM, Allbritton NL. Automated microarray platform for single-cell sorting and collection of lymphocytes following HIV reactivation. Bioengineering & Translational Medicine. 8: e10551. PMID 37693052 DOI: 10.1002/btm2.10551  0.372
2023 Cortés-Llanos B, Jain V, Volkheimer A, Browne EP, Murdoch DM, Allbritton NL. Automated microarray for single-cell sorting and collection of lymphocytes following HIV reactivation. Biorxiv : the Preprint Server For Biology. PMID 36778314 DOI: 10.1101/2023.02.02.526757  0.365
2021 Jefferys SR, Burgos SD, Peterson JJ, Selitsky SR, Turner AM, James LI, Tsai YH, Coffey AR, Margolis DM, Parker J, Browne EP. Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors. Plos Pathogens. 17: e1009346. PMID 33635929 DOI: 10.1371/journal.ppat.1009346  0.391
2020 Nekongo EE, Ponomarenko AI, Dewal MB, Butty VL, Browne EP, Shoulders MD. HSF1 Activation Can Restrict HIV Replication. Acs Infectious Diseases. PMID 32502335 DOI: 10.1021/Acsinfecdis.0C00166  0.394
2020 Turner AM, Dronamraju R, Potjewyd FM, Sholtis K, Winecoff D, Kirchherr J, Archin N, Browne E, Strahl BD, Margolis D, James LI. Evaluation of EED Inhibitors as a Class of PRC2-Targeted Small Molecules for HIV Latency Reversal. Acs Infectious Diseases. PMID 32347704 DOI: 10.1021/Acsinfecdis.9B00514  0.431
2020 Nixon CC, Mavigner M, Sampey GC, Brooks AD, Spagnuolo RA, Irlbeck DM, Mattingly C, Ho PT, Schoof N, Cammon CG, Tharp GK, Kanke M, Wang Z, Cleary RA, Upadhyay AA, ... ... Browne EP, et al. Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo. Nature. PMID 31969707 DOI: 10.1038/S41586-020-1951-3  0.393
2019 Arazi A, Rao DA, Berthier CC, Davidson A, Liu Y, Hoover PJ, Chicoine A, Eisenhaure TM, Jonsson AH, Li S, Lieb DJ, Zhang F, Slowikowski K, Browne EP, Noma A, et al. The immune cell landscape in kidneys of patients with lupus nephritis. Nature Immunology. PMID 31209404 DOI: 10.1038/S41590-019-0398-X  0.379
2019 Reyes M, Vickers D, Billman K, Eisenhaure T, Hoover P, Browne EP, Rao DA, Hacohen N, Blainey PC. Multiplexed enrichment and genomic profiling of peripheral blood cells reveal subset-specific immune signatures. Science Advances. 5: eaau9223. PMID 30746468 DOI: 10.1126/Sciadv.Aau9223  0.36
2019 Berthier CC, Arazi A, Rao D, Davidson A, Browne E, Eisenhaure T, Hacohen N, Lieb DJ, Diamond B, Kretzler M. 204 The immune cell landscape in kidneys of lupus nephritis patients Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.204  0.356
2018 Bradley T, Ferrari G, Haynes BF, Margolis DM, Browne EP. Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency. Cell Reports. 25: 107-117.e3. PMID 30282021 DOI: 10.1016/J.Celrep.2018.09.020  0.464
2017 Berthier C, Rao D, Arazi A, Browne E, Eisenhaure T, Hacohen N, Lieb D, Diamond B, Kretzler M. 264 Pearl: pathway exploration and analysis in renal disease in the accelerating medicine partnership (amp) lupus network Lupus Science & Medicine. 4. DOI: 10.1136/Lupus-2017-000215.264  0.324
2016 Cadena C, Stavrou S, Manzoni T, Iyer SS, Bibollet-Ruche F, Zhang W, Hahn BH, Browne EP, Ross SR. The effect of HIV-1 Vif polymorphisms on A3G anti-viral activity in an in vivo mouse model. Retrovirology. 13: 45. PMID 27363431 DOI: 10.1186/S12977-016-0280-Y  0.405
2016 Browne EP, Letham B, Rudin C. A Computational Model of Inhibition of HIV-1 by Interferon-Alpha. Plos One. 11: e0152316. PMID 27010978 DOI: 10.1371/Journal.Pone.0152316  0.434
2016 Tas JM, Mesin L, Pasqual G, Targ S, Jacobsen JT, Mano YM, Chen CS, Weill JC, Reynaud CA, Browne EP, Meyer-Hermann M, Victora GD. Visualizing antibody affinity maturation in germinal centers. Science (New York, N.Y.). PMID 26912368 DOI: 10.1126/Science.Aad3439  0.303
2015 Browne EP. An interleukin-1 beta-encoding retrovirus exhibits enhanced replication in vivo. Journal of Virology. 89: 155-64. PMID 25320301 DOI: 10.1128/Jvi.02314-14  0.302
2014 Stavrou S, Crawford D, Blouch K, Browne EP, Kohli RM, Ross SR. Different modes of retrovirus restriction by human APOBEC3A and APOBEC3G in vivo. Plos Pathogens. 10: e1004145. PMID 24851906 DOI: 10.1371/Journal.Ppat.1004145  0.402
2013 Browne EP. Toll-like receptor 7 inhibits early acute retroviral infection through rapid lymphocyte responses. Journal of Virology. 87: 7357-66. PMID 23616654 DOI: 10.1128/Jvi.00788-13  0.405
2012 Browne EP. Regulation of B-cell responses by Toll-like receptors. Immunology. 136: 370-9. PMID 22444240 DOI: 10.1111/J.1365-2567.2012.03587.X  0.386
2012 Nassar RA, Browne EP, Chen J, Klibanov AM. Removing human immunodeficiency virus (HIV) from human blood using immobilized heparin. Biotechnology Letters. 34: 853-6. PMID 22207147 DOI: 10.1007/S10529-011-0840-0  0.361
2011 Browne EP. Toll-like receptor 7 controls the anti-retroviral germinal center response. Plos Pathogens. 7: e1002293. PMID 21998589 DOI: 10.1371/Journal.Ppat.1002293  0.388
2009 Browne EP, Allers C, Landau NR. Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent. Virology. 387: 313-21. PMID 19304304 DOI: 10.1016/J.Virol.2009.02.026  0.414
2009 Browne EP, Littman DR. Myd88 is required for an antibody response to retroviral infection. Plos Pathogens. 5: e1000298. PMID 19214214 DOI: 10.1371/Journal.Ppat.1000298  0.402
2008 Browne EP, Littman DR. Species-specific restriction of apobec3-mediated hypermutation. Journal of Virology. 82: 1305-13. PMID 18032489 DOI: 10.1128/Jvi.01371-07  0.355
2005 Browne EP, Li J, Chong M, Littman DR. Virus-host interactions: new insights from the small RNA world. Genome Biology. 6: 238. PMID 16277756 DOI: 10.1186/Gb-2005-6-11-238  0.328
2004 Challacombe JF, Rechtsteiner A, Gottardo R, Rocha LM, Browne EP, Shenk T, Altherr MR, Brettin TS. Evaluation of the host transcriptional response to human cytomegalovirus infection. Physiological Genomics. 18: 51-62. PMID 15069167 DOI: 10.1152/Physiolgenomics.00155.2003  0.535
2003 Browne EP, Shenk T. Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 11439-44. PMID 12972646 DOI: 10.1073/Pnas.1534570100  0.564
2001 Browne EP, Wing B, Coleman D, Shenk T. Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs. Journal of Virology. 75: 12319-30. PMID 11711622 DOI: 10.1128/Jvi.75.24.12319-12330.2001  0.545
2001 Wing BA, Browne EP, Shenk T. DNA microarrays: A powerful new tool for analysis of the virus-host interaction Drug Discovery Today. 6.  0.3
Low-probability matches (unlikely to be authored by this person)
2022 Falcinelli SD, Peterson JJ, Turner AW, Irlbeck D, Read J, Raines SL, James KS, Sutton C, Sanchez A, Emery A, Sampey G, Ferris R, Allard B, Ghofrani S, Kirchherr JL, ... ... Browne EP, et al. Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo. The Journal of Clinical Investigation. 132. PMID 35426377 DOI: 10.1172/JCI157281  0.299
2020 Wahl A, Gralinski L, Johnson C, Yao W, Kovarova M, Dinnon K, Liu H, Madden V, Krzystek H, De C, White K, Schäfer A, Zaman T, Leist S, Grant P, ... ... Browne E, et al. Acute SARS-CoV-2 Infection is Highly Cytopathic, Elicits a Robust Innate Immune Response and is Efficiently Prevented by EIDD-2801. Research Square. PMID 32995766 DOI: 10.21203/rs.3.rs-80404/v1  0.296
2020 Browne EP. The Role of Toll-Like Receptors in Retroviral Infection. Microorganisms. 8. PMID 33202596 DOI: 10.3390/microorganisms8111787  0.295
2019 Arazi A, Rao DA, Berthier CC, Davidson A, Liu Y, Hoover PJ, Chicoine A, Eisenhaure TM, Jonsson AH, Li S, Lieb DJ, Zhang F, Slowikowski K, Browne EP, Noma A, et al. Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis. Nature Immunology. PMID 31409923 DOI: 10.1038/S41590-019-0473-3  0.29
2022 Li D, Wong LM, Tang Y, Allard B, James KS, Thompson GR, Dandekar S, Browne EP, Li Q, Simon JM, Archin NM, Margolis DM, Jiang G. Depletion of HIV reservoir by activation of ISR signaling in resting CD4T cells. Iscience. 26: 105743. PMID 36590168 DOI: 10.1016/j.isci.2022.105743  0.288
2021 Wahl A, Gralinski LE, Johnson CE, Yao W, Kovarova M, Dinnon KH, Liu H, Madden VJ, Krzystek HM, De C, White KK, Gully K, Schäfer A, Zaman T, Leist SR, ... ... Browne EP, et al. SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801. Nature. PMID 33561864 DOI: 10.1038/s41586-021-03312-w  0.278
2018 Mahoney KM, Shukla SA, Patsoukis N, Chaudhri A, Browne EP, Arazi A, Eisenhaure TM, Pendergraft WF, Hua P, Pham HC, Bu X, Zhu B, Hacohen N, Fritsch EF, Boussiotis VA, et al. A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression. Cancer Immunology, Immunotherapy : Cii. PMID 30564891 DOI: 10.1007/S00262-018-2282-1  0.275
2023 Semenova L, Wang Y, Falcinelli S, Archin N, Cooper-Volkheimer AD, Margolis DM, Goonetilleke N, Murdoch DM, Rudin CD, Browne EP. Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy. Biorxiv : the Preprint Server For Biology. PMID 38014340 DOI: 10.1101/2023.11.16.567386  0.272
2012 Drake A, Browne E, Phennicie R, Chen J. Dendritic cell nediated inhibition of lentiviral infection Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P178  0.271
2018 Donlin LT, Rao DA, Wei K, Slowikowski K, McGeachy MJ, Turner JD, Meednu N, Mizoguchi F, Gutierrez-Arcelus M, Lieb DJ, Keegan J, Muskat K, Hillman J, Rozo C, Ricker E, ... ... Browne EP, et al. Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue. Arthritis Research & Therapy. 20: 139. PMID 29996944 DOI: 10.1186/S13075-018-1631-Y  0.268
2023 Falcinelli SD, Cooper-Volkheimer AD, Semenova L, Wu E, Richardson A, Ashokkumar M, Margolis DM, Archin NM, Rudin CD, Murdoch D, Browne EP. Impact of cannabis use on immune cell populations and the viral reservoir in people with HIV on suppressive antiretroviral therapy. The Journal of Infectious Diseases. PMID 37606598 DOI: 10.1093/infdis/jiad364  0.266
2023 Hsieh E, Janssens DH, Paddison PJ, Browne EP, Henikoff S, OhAinle M, Emerman M. A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency. Plos Pathogens. 19: e1011101. PMID 36706161 DOI: 10.1371/journal.ppat.1011101  0.263
2023 Peterson JJ, Lewis CA, Burgos SD, Manickam A, Xu Y, Rowley AA, Clutton G, Richardson B, Zou F, Simon JM, Margolis DM, Goonetilleke N, Browne EP. A histone deacetylase network regulates epigenetic reprogramming and viral silencing in HIV-infected cells. Cell Chemical Biology. 30: 1617-1633.e9. PMID 38134881 DOI: 10.1016/j.chembiol.2023.11.009  0.262
2022 Li D, Dewey MG, Wang L, Falcinelli SD, Wong LM, Tang Y, Browne EP, Chen X, Archin NM, Margolis DM, Jiang G. Crotonylation sensitizes IAPi-induced disruption of latent HIV by enhancing p100 cleavage into p52. Iscience. 25: 103649. PMID 35024584 DOI: 10.1016/j.isci.2021.103649  0.254
2016 Letham B, Letham PA, Rudin C, Browne EP. Prediction uncertainty and optimal experimental design for learning dynamical systems. Chaos (Woodbury, N.Y.). 26: 063110. PMID 27368775 DOI: 10.1063/1.4953795  0.234
2012 Browne E. Toll Like receptor 7 regulates viral loads and cytokine secretion during acute retroviral infection Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P174  0.232
2000 Browne EP, Bellamy AR, Taylor JA. Membrane-destabilizing activity of rotavirus NSP4 is mediated by a membrane-proximal amphipathic domain Journal of General Virology. 81: 1955-1959. PMID 10900033 DOI: 10.1099/0022-1317-81-8-1955  0.228
2023 Lewis CA, Margolis DM, Browne EP. New Concepts in Therapeutic Manipulation of HIV-1 Transcription and Latency: Latency Reversal versus Latency Prevention. Viruses. 15. PMID 37632019 DOI: 10.3390/v15081677  0.211
2017 Letham B, Letham PA, Rudin C, Browne EP. Erratum: "Prediction uncertainty and optimal experimental design for learning dynamical systems" [Chaos 26, 063110 (2016)]. Chaos (Woodbury, N.Y.). 27: 069901. PMID 28679220 DOI: 10.1063/1.4986799  0.185
2023 Donnelly J, Katta S, Rudin C, Browne EP. The Rashomon Importance Distribution: Getting RID of Unstable, Single Model-based Variable Importance. Arxiv. PMID 37808086  0.182
2021 Lo JA, Kawakubo M, Juneja VR, Su MY, Erlich TH, LaFleur MW, Kemeny LV, Rashid M, Malehmir M, Rabi SA, Raghavan R, Allouche J, Kasumova G, Frederick DT, Pauken KE, ... ... Browne EP, et al. Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses. Science Translational Medicine. 13. PMID 33597266 DOI: 10.1126/scitranslmed.abd8636  0.181
2022 Novak A, Laughton D, Lane R, Blackham E, Thomas J, Chatzopoulou E, Wrigglesworth J, Quddus A, Ahmed S, Cousin D, Duffy L, Dubois N, Unitt J, Orban K, Browne E, et al. Discovery and Optimization of Potent and Orally Available CTP Synthetase Inhibitors for Use in Treatment of Diseases Driven by Aberrant Immune Cell Proliferation. Journal of Medicinal Chemistry. PMID 36449304 DOI: 10.1021/acs.jmedchem.2c01446  0.128
2016 Fitzgerald LM, Browne EP, Christie KD, Punska EC, Simmons LO, Williams KE, Pentecost BT, M Jawale R, Otis CN, Arcaro KF. ELF5 and DOK7 regulation in anti-estrogen treated cells and tumors. Cancer Cell International. 16: 8. PMID 26884724 DOI: 10.1186/S12935-016-0282-9  0.122
2012 Qin W, Zhang K, Kliethermes B, Ruhlen RL, Browne EP, Arcaro KF, Sauter ER. Differential expression of cancer associated proteins in breast milk based on age at first full term pregnancy Bmc Cancer. 100. PMID 22436421 DOI: 10.1186/1471-2407-12-100  0.086
2014 Browne EP, Dinc SE, Punska EC, Agus S, Vitrinel A, Erdag GC, Anderton DL, Arcaro KF, Yilmaz B. Promoter methylation in epithelial-enriched and epithelial-depleted cell populations isolated from breast milk. Journal of Human Lactation : Official Journal of International Lactation Consultant Association. 30: 450-7. PMID 25164041 DOI: 10.1177/0890334414548224  0.085
2024 Cui Y, Lanne A, Peng X, Browne E, Bhatt A, Coltman NJ, Craven P, Cox LR, Cundy NJ, Dale K, Feula A, Frampton J, Fung M, Morton M, Goff A, et al. Azetidines Kill Multidrug-Resistant without Detectable Resistance by Blocking Mycolate Assembly. Journal of Medicinal Chemistry. PMID 38331432 DOI: 10.1021/acs.jmedchem.3c01643  0.082
2022 Huang H, Wang Y, Rudin C, Browne EP. Towards a comprehensive evaluation of dimension reduction methods for transcriptomic data visualization. Communications Biology. 5: 719. PMID 35853932 DOI: 10.1038/s42003-022-03628-x  0.069
2009 Browne EP, Stapleton HM, Kelly SM, Tilton SC, Gallagher EP. In vitro hepatic metabolism of 2,2',4,4',5-pentabromodiphenyl ether (BDE 99) in Chinook salmon (Onchorhynchus tshawytscha). Aquatic Toxicology (Amsterdam, Netherlands). 92: 281-7. PMID 19346012 DOI: 10.1016/J.Aquatox.2009.02.017  0.064
2011 Browne EP, Punska EC, Lenington S, Otis CN, Anderton DL, Arcaro KF. Increased promoter methylation in exfoliated breast epithelial cells in women with a previous breast biopsy. Epigenetics. 6: 1425-35. PMID 22139572 DOI: 10.4161/Epi.6.12.18280  0.064
2014 Zimmers SM, Browne EP, O'Keefe PW, Anderton DL, Kramer L, Reckhow DA, Arcaro KF. Determination of free Bisphenol A (BPA) concentrations in breast milk of U.S. women using a sensitive LC/MS/MS method. Chemosphere. 104: 237-43. PMID 24507723 DOI: 10.1016/J.Chemosphere.2013.12.085  0.047
2015 Yang HP, Schneider SS, Chisholm CM, Browne EP, Mahmood S, Gierach GL, Lenington S, Anderton DL, Sherman ME, Arcaro KF. Association of TGF-β2 levels in breast milk with severity of breast biopsy diagnosis. Cancer Causes & Control : Ccc. 26: 345-54. PMID 25604865 DOI: 10.1007/S10552-014-0498-8  0.044
2016 Murphy J, Sherman ME, Browne EP, Caballero AI, Punska EC, Pfeiffer RM, Yang HP, Lee M, Yang H, Gierach GL, Arcaro KF. Potential of breastmilk analysis to inform early events in breast carcinogenesis: rationale and considerations. Breast Cancer Research and Treatment. PMID 27107568 DOI: 10.1007/S10549-016-3796-X  0.043
2012 Arcaro KF, Browne EP, Qin W, Zhang K, Anderton DL, Sauter ER. Differential expression of cancer-related proteins in paired breast milk samples from women with breast cancer. Journal of Human Lactation : Official Journal of International Lactation Consultant Association. 28: 543-6. PMID 22914689 DOI: 10.1177/0890334412453205  0.03
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