| Year |
Citation |
Score |
| 2024 |
Soto Ocaña J, Friedman ES, Keenan O, Bayard NU, Ford E, Tanes C, Munneke MJ, Beavers WN, Skaar EP, Bittinger K, Zemel BS, Wu GD, Zackular JP. Metal availability shapes early life microbial ecology and community succession. Mbio. e0153424. PMID 39440978 DOI: 10.1128/mbio.01534-24 |
0.662 |
|
| 2024 |
Boyd JM, Ryan Kaler K, Esquilín-Lebrón K, Pall A, Campbell CJ, Foley ME, Rios-Delgado G, Mustor EM, Stephens TG, Bovermann H, Greco TM, Cristea IM, Carabetta VJ, Beavers WN, Bhattacharya D, ... Skaar EP, et al. Fpa (YlaN) is an iron(II) binding protein that functions to relieve Fur-mediated repression of gene expression in . Mbio. e0231024. PMID 39440976 DOI: 10.1128/mbio.02310-24 |
0.683 |
|
| 2024 |
Freiberg JA, Reyes Ruiz VM, Gimza BD, Murdoch CC, Green ER, Curry JM, Cassat JE, Skaar EP. Restriction of arginine induces antibiotic tolerance in Staphylococcus aureus. Nature Communications. 15: 6734. PMID 39112491 DOI: 10.1038/s41467-024-51144-9 |
0.323 |
|
| 2024 |
Pi H, Carlin SM, Beavers WN, Hillebrand GH, Krystofiak ES, Stauff DL, Skaar EP. FapR regulates HssRS-mediated heme homeostasis in . Biorxiv : the Preprint Server For Biology. PMID 39026866 DOI: 10.1101/2024.07.08.602573 |
0.718 |
|
| 2023 |
Pi H, Sun R, McBride JR, Kruse ARS, Gibson-Corley KN, Krystofiak ES, Nicholson MR, Spraggins JM, Zhou Q, Skaar EP. Clostridioides difficile ferrosome organelles combat nutritional immunity. Nature. 623: 1009-1016. PMID 37968387 DOI: 10.1038/s41586-023-06719-9 |
0.335 |
|
| 2023 |
Freiberg JA, Ruiz VMR, Green ER, Skaar EP. Restriction of Arginine Induces Antibiotic Tolerance in . Biorxiv : the Preprint Server For Biology. PMID 37873095 DOI: 10.1101/2023.10.12.561972 |
0.318 |
|
| 2023 |
Spiga L, Fansler RT, Perera YR, Shealy NG, Munneke MJ, David HE, Torres TP, Lemoff A, Ran X, Richardson KL, Pudlo N, Martens EC, Folta-Stogniew E, Yang ZJ, Skaar EP, et al. Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection. Cell Host & Microbe. PMID 37776864 DOI: 10.1016/j.chom.2023.08.018 |
0.337 |
|
| 2023 |
Leasure CS, Grunenwald CM, Choby JE, Sauer JD, Skaar EP. Maintenance of heme homeostasis in through post-translational regulation of glutamyl-tRNA reductase. Journal of Bacteriology. e0017123. PMID 37655914 DOI: 10.1128/jb.00171-23 |
0.813 |
|
| 2023 |
Spiga L, Fansler RT, Perera YR, Shealy NG, Munneke MJ, Torres TP, David HE, Lemoff A, Ran X, Richardson KL, Pudlo N, Martens EC, Yang ZJ, Skaar EP, Byndloss MX, et al. Iron acquisition by a commensal bacterium modifies host nutritional immunity during infection. Biorxiv : the Preprint Server For Biology. PMID 37425782 DOI: 10.1101/2023.06.25.546471 |
0.334 |
|
| 2023 |
Norambuena J, Al-Tameemi H, Bovermann H, Kim J, Beavers WN, Skaar EP, Parker D, Boyd JM. Copper ions inhibit pentose phosphate pathway function in Staphylococcus aureus. Plos Pathogens. 19: e1011393. PMID 37235600 DOI: 10.1371/journal.ppat.1011393 |
0.653 |
|
| 2023 |
Voss K, Sewell AE, Krystofiak ES, Gibson-Corley KN, Young AC, Basham JH, Sugiura A, Arner EN, Beavers WN, Kunkle DE, Dickson ME, Needle GA, Skaar EP, Rathmell WK, Ormseth MJ, et al. Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus. Science Immunology. 8: eabq0178. PMID 36638190 DOI: 10.1126/sciimmunol.abq0178 |
0.642 |
|
| 2022 |
Smith AB, Jenior ML, Keenan O, Hart JL, Specker J, Abbas A, Rangel PC, Di C, Green J, Bustin KA, Gaddy JA, Nicholson MR, Laut C, Kelly BJ, Matthews ML, ... ... Skaar EP, et al. Enterococci enhance Clostridioides difficile pathogenesis. Nature. PMID 36385534 DOI: 10.1038/s41586-022-05438-x |
0.633 |
|
| 2022 |
Sheldon JR, Himmel LE, Kunkle DE, Monteith AJ, Maloney KN, Skaar EP. Lipocalin-2 is an essential component of the innate immune response to Acinetobacter baumannii infection. Plos Pathogens. 18: e1010809. PMID 36054235 DOI: 10.1371/journal.ppat.1010809 |
0.419 |
|
| 2022 |
Afzal A, Beavers WN, Skaar EP, Calhoun MC, Richardson KA, Landstreet SR, Cliffel DE, Wright D, Bastarache JA, Ware LB. Ultraviolet light oxidation of fresh hemoglobin eliminates aggregate formation seen in commercially sourced hemoglobin. Blood Cells, Molecules & Diseases. 98: 102699. PMID 36027791 DOI: 10.1016/j.bcmd.2022.102699 |
0.664 |
|
| 2022 |
Ameka MK, Beavers WN, Shaver CM, Ware LB, Kerchberger VE, Schoenfelt KQ, Sun L, Koyama T, Skaar EP, Becker L, Hasty AH. An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload. International Journal of Molecular Sciences. 23. PMID 35806422 DOI: 10.3390/ijms23137417 |
0.668 |
|
| 2022 |
Perry WJ, Grunenwald CM, Van de Plas R, Witten JC, Martin DR, Apte SS, Cassat JE, Pettersson GB, Caprioli RM, Skaar EP, Spraggins JM. Visualizing Staphylococcus aureus pathogenic membrane modification within the host infection environment by multimodal imaging mass spectrometry. Cell Chemical Biology. PMID 35654040 DOI: 10.1016/j.chembiol.2022.05.004 |
0.802 |
|
| 2022 |
Weiss A, Murdoch CC, Edmonds KA, Jordan MR, Monteith AJ, Perera YR, Rodríguez Nassif AM, Petoletti AM, Beavers WN, Munneke MJ, Drury SL, Krystofiak ES, Thalluri K, Wu H, Kruse ARS, ... ... Skaar EP, et al. Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis. Cell. PMID 35584702 DOI: 10.1016/j.cell.2022.04.011 |
0.669 |
|
| 2022 |
Green ER, Fakhoury JN, Monteith AJ, Pi H, Giedroc DP, Skaar EP. Bacterial hydrophilins promote pathogen desiccation tolerance. Cell Host & Microbe. PMID 35413266 DOI: 10.1016/j.chom.2022.03.019 |
0.456 |
|
| 2022 |
Rivera-Lugo R, Deng D, Anaya-Sanchez A, Tejedor-Sanz S, Tang E, Reyes Ruiz VM, Smith HB, Titov DV, Sauer JD, Skaar EP, Ajo-Franklin CM, Portnoy DA, Light SH. requires cellular respiration for NAD regeneration and pathogenesis. Elife. 11. PMID 35380108 DOI: 10.7554/eLife.75424 |
0.453 |
|
| 2022 |
Beavers WN, Munneke MJ, Stackhouse AR, Freiberg JA, Skaar EP. Host Polyunsaturated Fatty Acids Potentiate Aminoglycoside Killing of Staphylococcus aureus. Microbiology Spectrum. e0276721. PMID 35377191 DOI: 10.1128/spectrum.02767-21 |
0.749 |
|
| 2022 |
Pi H, Weiss A, Laut CL, Grunenwald CM, Lin HK, Yi XI, Stauff DL, Skaar EP. An RNA-binding protein acts as a major post-transcriptional modulator in Bacillus anthracis. Nature Communications. 13: 1491. PMID 35314695 DOI: 10.1038/s41467-022-29209-4 |
0.773 |
|
| 2022 |
Monteith AJ, Miller JM, Beavers WN, Juttukonda LJ, Skaar EP. Increased dietary manganese impairs NET formation rendering neutrophils ineffective at combating . Infection and Immunity. iai0068521. PMID 35191757 DOI: 10.1128/iai.00685-21 |
0.705 |
|
| 2022 |
Skaar EP, Echols R, Matsunaga Y, Menon A, Portsmouth S. Iron serum levels and iron homeostasis parameters in patients with nosocomial pneumonia treated with cefiderocol: post hoc analysis of the APEKS-NP study. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. PMID 35025025 DOI: 10.1007/s10096-021-04399-9 |
0.341 |
|
| 2022 |
Munneke MJ, Skaar EP. Ornithine supports C. difficile gut carriage. Nature Metabolism. 4: 7-8. PMID 34992298 DOI: 10.1038/s42255-021-00510-8 |
0.241 |
|
| 2022 |
Monteith AJ, Miller JM, Williams JM, Voss K, Rathmell JC, Crofford LJ, Skaar EP. Altered Mitochondrial Homeostasis during Systemic Lupus Erythematosus Impairs Neutrophil Extracellular Trap Formation Rendering Neutrophils Ineffective at Combating . Journal of Immunology (Baltimore, Md. : 1950). 208: 454-463. PMID 34930781 DOI: 10.4049/jimmunol.2100752 |
0.371 |
|
| 2021 |
Weiss A, Lopez CA, Beavers WN, Rodriguez J, Skaar EP. strain-dependent and strain-independent adaptations to a microaerobic environment. Microbial Genomics. 7. PMID 34908523 DOI: 10.1099/mgen.0.000738 |
0.687 |
|
| 2021 |
Monteith AJ, Miller JM, Beavers WN, Maloney KN, Seifert EL, Hajnoczky G, Skaar EP. Mitochondrial calcium uniporter affects neutrophil bactericidal activity during infection. Infection and Immunity. IAI0055121. PMID 34871043 DOI: 10.1128/IAI.00551-21 |
0.701 |
|
| 2021 |
Behnsen J, Zhi H, Aron AT, Subramanian V, Santus W, Lee MH, Gerner RR, Petras D, Liu JZ, Green KD, Price SL, Camacho J, Hillman H, Tjokrosurjo J, Montaldo NP, ... ... Skaar EP, et al. Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut. Nature Communications. 12: 7016. PMID 34853318 DOI: 10.1038/s41467-021-27297-2 |
0.429 |
|
| 2021 |
Laut CL, Leasure CS, Pi H, Carlin SM, Chu ML, Hillebrand GH, Lin HK, Yi XI, Stauff DL, Skaar EP. DnaJ and ClpX are required for HitRS and HssRS two-component system signaling in . Infection and Immunity. IAI0056021. PMID 34748369 DOI: 10.1128/IAI.00560-21 |
0.785 |
|
| 2021 |
Monteith AJ, Miller JM, Maxwell CN, Chazin WJ, Skaar EP. Neutrophil extracellular traps enhance macrophage killing of bacterial pathogens. Science Advances. 7: eabj2101. PMID 34516771 DOI: 10.1126/sciadv.abj2101 |
0.366 |
|
| 2021 |
Drury SL, Miller AR, Laut CL, Walter AB, Bennett MR, Su M, Bai M, Jing B, Joseph SB, Metzger EJ, Bane CE, Black CC, Macdonald MT, Dutter BF, Romaine IM, ... ... Skaar EP, et al. Simultaneous exposure to intracellular and extracellular photosensitizers for the treatment of infections. Antimicrobial Agents and Chemotherapy. AAC0091921. PMID 34516248 DOI: 10.1128/AAC.00919-21 |
0.374 |
|
| 2021 |
Wexler AG, Guiberson ER, Beavers WN, Shupe JA, Washington MK, Lacy DB, Caprioli RM, Spraggins JM, Skaar EP. Clostridioides difficile infection induces a rapid influx of bile acids into the gut during colonization of the host. Cell Reports. 36: 109683. PMID 34496241 DOI: 10.1016/j.celrep.2021.109683 |
0.764 |
|
| 2021 |
Monteith AJ, Skaar EP. The impact of metal availability on immune function during infection. Trends in Endocrinology and Metabolism: Tem. PMID 34483037 DOI: 10.1016/j.tem.2021.08.004 |
0.401 |
|
| 2021 |
Wijers CDM, Pham L, Menon S, Boyd KL, Noel HR, Skaar E, Gaddy JA, Palmer LD, Noto MJ. Identification of two variants of 17978 with distinct genotypes and phenotypes. Infection and Immunity. IAI0045421. PMID 34460288 DOI: 10.1128/IAI.00454-21 |
0.609 |
|
| 2021 |
Santos RERS, da Silva Júnior WP, Harrison S, Skaar EP, Chazin WJ, da Silva Neto JF. The zinc transporter ZnuABC is critical for the virulence of and contributes to diverse zinc-dependent physiological processes. Infection and Immunity. IAI0031121. PMID 34370507 DOI: 10.1128/IAI.00311-21 |
0.487 |
|
| 2021 |
Skaar EP. Imaging Infection Across Scales of Size: From Whole Animals to Single Molecules. Annual Review of Microbiology. PMID 34343016 DOI: 10.1146/annurev-micro-041521-121457 |
0.316 |
|
| 2021 |
Beavers WN, DuMont AL, Monteith AJ, Maloney KN, Tallman KA, Weiss A, Christian AH, Toste FD, Chang CJ, Porter NA, Torres VJ, Skaar EP. peptide methionine sulfoxide reductases protect from human whole blood killing. Infection and Immunity. PMID 34001560 DOI: 10.1128/IAI.00146-21 |
0.789 |
|
| 2021 |
Bisht K, Moore JL, Caprioli RM, Skaar EP, Wakeman CA. Impact of temperature-dependent phage expression on Pseudomonas aeruginosa biofilm formation. Npj Biofilms and Microbiomes. 7: 22. PMID 33727555 DOI: 10.1038/s41522-021-00194-8 |
0.791 |
|
| 2021 |
Klopfenstein N, Cassat JE, Monteith A, Miller A, Drury S, Skaar E, Serezani CH. Murine Models for Staphylococcal Infection. Current Protocols. 1: e52. PMID 33656290 DOI: 10.1002/cpz1.52 |
0.339 |
|
| 2020 |
Pi H, Chu ML, Ivan SJ, Latario CJ, Toth AM, Carlin SM, Hillebrand GH, Lin HK, Reppart JD, Stauff DL, Skaar EP. Directed evolution reveals the mechanism of HitRS signaling transduction in Bacillus anthracis. Plos Pathogens. 16: e1009148. PMID 33362282 DOI: 10.1371/journal.ppat.1009148 |
0.297 |
|
| 2020 |
Guiberson ER, Weiss A, Ryan DJ, Monteith AJ, Sharman K, Gutierrez DB, Perry WJ, Caprioli RM, Skaar EP, Spraggins JM. Spatially Targeted Proteomics of the Host-Pathogen Interface during Staphylococcal Abscess Formation. Acs Infectious Diseases. PMID 33270421 DOI: 10.1021/acsinfecdis.0c00647 |
0.433 |
|
| 2020 |
Bozhanova NG, Calcutt MW, Beavers WN, Brown BP, Skaar EP, Meiler J. Lipocalin Blc is a potential heme-binding protein. Febs Letters. PMID 33210733 DOI: 10.1002/1873-3468.14001 |
0.698 |
|
| 2020 |
Juttukonda LJ, Beavers WN, Unsihuay D, Kim K, Pishchany G, Horning KJ, Weiss A, Al-Tameemi H, Boyd JM, Sulikowski GA, Bowman AB, Skaar EP. A Small-Molecule Modulator of Metal Homeostasis in Gram-Positive Pathogens. Mbio. 11. PMID 33109764 DOI: 10.1128/mBio.02555-20 |
0.706 |
|
| 2020 |
Sheldon JR, Skaar EP. Acinetobacter baumannii can use multiple siderophores for iron acquisition, but only acinetobactin is required for virulence. Plos Pathogens. 16: e1008995. PMID 33075115 DOI: 10.1371/journal.ppat.1008995 |
0.48 |
|
| 2020 |
Al-Tameemi H, Beavers WN, Norambuena J, Skaar EP, Boyd JM. Staphylococcus aureus lacking a functional MntABC manganese import system have increased resistance to copper. Molecular Microbiology. PMID 33034093 DOI: 10.1111/mmi.14623 |
0.671 |
|
| 2020 |
Parnell JM, Fazili I, Bloch SC, Lacy DB, Garcia-Lopez VA, Bernard R, Skaar EP, Edwards KM, Nicholson MR. Two-Step Testing for Clostridioides Difficile is Inadequate in Differentiating Infection From Colonization in Children. Journal of Pediatric Gastroenterology and Nutrition. PMID 32925555 DOI: 10.1097/Mpg.0000000000002944 |
0.579 |
|
| 2020 |
Palmer LD, Minor KE, Mettlach JA, Rivera ES, Boyd KL, Caprioli RM, Spraggins JM, Dalebroux ZD, Skaar EP. Modulating Isoprenoid Biosynthesis Increases Lipooligosaccharides and Restores Acinetobacter baumannii Resistance to Host and Antibiotic Stress. Cell Reports. 32: 108129. PMID 32905776 DOI: 10.1016/J.Celrep.2020.108129 |
0.488 |
|
| 2020 |
Becker SH, Ulrich K, Dhabaria A, Ueberheide B, Beavers W, Skaar EP, Iyer LM, Aravind L, Jakob U, Darwin KH. Mycobacterium tuberculosis Rv0991c Is a Redox-Regulated Molecular Chaperone. Mbio. 11. PMID 32843553 DOI: 10.1128/Mbio.01545-20 |
0.728 |
|
| 2020 |
Le NH, Peters K, Espaillat A, Sheldon JR, Gray J, Di Venanzio G, Lopez J, Djahanschiri B, Mueller EA, Hennon SW, Levin PA, Ebersberger I, Skaar EP, Cava F, Vollmer W, et al. Peptidoglycan editing provides immunity to during bacterial warfare. Science Advances. 6: eabb5614. PMID 32832672 DOI: 10.1126/Sciadv.Abb5614 |
0.446 |
|
| 2020 |
Ray A, Edmonds KA, Palmer LD, Skaar EP, Giedroc DP. Staphylococcus aureus glucose-induced biofilm accessory protein A (GbaA) is a monothiol-dependent electrophile sensor. Biochemistry. PMID 32697076 DOI: 10.1021/Acs.Biochem.0C00347 |
0.456 |
|
| 2020 |
Walsh BJC, Wang J, Edmonds KA, Palmer LD, Zhang Y, Trinidad JC, Skaar EP, Giedroc DP. The Response of to Hydrogen Sulfide Reveals Two Independent Persulfide-Sensing Systems and a Connection to Biofilm Regulation. Mbio. 11. PMID 32576676 DOI: 10.1128/Mbio.01254-20 |
0.533 |
|
| 2020 |
Duggan S, Laabei M, Alnahari A, O'Brien EC, Lacey KA, Bacon L, Heesom K, Fu CL, Otto M, Skaar E, McLoughlin RM, Massey RC. A small membrane stabilising protein critical to the pathogenicity of Infection and Immunity. PMID 32571989 DOI: 10.1128/Iai.00162-20 |
0.484 |
|
| 2020 |
Knippel RJ, Wexler AG, Miller JM, Beavers WN, Weiss A, de Crécy-Lagard V, Edmonds KA, Giedroc DP, Skaar EP. Clostridioides difficile Senses and Hijacks Host Heme for Incorporation into an Oxidative Stress Defense System. Cell Host & Microbe. PMID 32526159 DOI: 10.1016/J.Chom.2020.05.015 |
0.759 |
|
| 2020 |
Syring KE, Bosma KJ, Goleva SB, Singh K, Oeser JK, Lopez CA, Skaar EP, McGuinness OP, Davis LK, Powell DR, O'Brien RM. Potential positive and negative consequences of ZnT8 inhibition. The Journal of Endocrinology. PMID 32485672 DOI: 10.1530/Joe-20-0138 |
0.364 |
|
| 2020 |
Skaar EP, Zackular JP. Editorial overview: Microbe-microbe interactions: the enemy of my enemy is my friend. Current Opinion in Microbiology. 53: iii-v. PMID 32434684 DOI: 10.1016/J.Mib.2020.05.001 |
0.345 |
|
| 2020 |
Lopez CA, McNeely TP, Nurmakova K, Beavers WN, Skaar EP. Clostridioides difficile proline fermentation in response to commensal clostridia. Anaerobe. 63: 102210. PMID 32422411 DOI: 10.1016/J.Anaerobe.2020.102210 |
0.712 |
|
| 2020 |
Lonergan ZR, Palmer LD, Skaar EP. Histidine utilization is a critical determinant of pathogenesis. Infection and Immunity. PMID 32341119 DOI: 10.1128/Iai.00118-20 |
0.529 |
|
| 2020 |
Laut CL, Perry WJ, Metzger AL, Weiss A, Stauff DL, Walker S, Caprioli RM, Skaar EP. Bacillus anthracis Responds to Targocil-Induced Envelope Damage through EdsRS Activation of Cardiolipin Synthesis. Mbio. 11. PMID 32234818 DOI: 10.1128/Mbio.03375-19 |
0.485 |
|
| 2020 |
Hood-Pishchany MI, Pham L, Wijers CD, Burns WJ, Boyd KL, Palmer LD, Skaar EP, Noto MJ. Broad-spectrum suppression of bacterial pneumonia by aminoglycoside-propagated Acinetobacter baumannii. Plos Pathogens. 16: e1008374. PMID 32168364 DOI: 10.1371/Journal.Ppat.1008374 |
0.512 |
|
| 2020 |
Zackular JP, Knippel RJ, Lopez CA, Beavers WN, Maxwell CN, Chazin WJ, Skaar EP. ZupT Facilitates Clostridioides difficile Resistance to Host-Mediated Nutritional Immunity. Msphere. 5. PMID 32161145 DOI: 10.1128/mSphere.00061-20 |
0.758 |
|
| 2020 |
Perry WJ, Weiss A, Van de Plas R, Spraggins JM, Caprioli RM, Skaar EP. Integrated molecular imaging technologies for investigation of metals in biological systems: A brief review. Current Opinion in Chemical Biology. 55: 127-135. PMID 32087551 DOI: 10.1016/J.Cbpa.2020.01.008 |
0.372 |
|
| 2019 |
Walter AB, Simpson J, Jenkins JL, Skaar EP, Jansen ED. Optimization of Optical Parameters for Improved Photodynamic Therapy of Staphylococcus aureus Using Endogenous Coproporphyrin III. Photodiagnosis and Photodynamic Therapy. 101624. PMID 31866531 DOI: 10.1016/J.Pdpdt.2019.101624 |
0.386 |
|
| 2019 |
Green ER, Juttukonda LJ, Skaar EP. The manganese-responsive transcriptional regulator MumR protects from oxidative stress. Infection and Immunity. PMID 31792075 DOI: 10.1128/Iai.00762-19 |
0.535 |
|
| 2019 |
Lopez CA, Beavers WN, Weiss A, Knippel RJ, Zackular JP, Chazin W, Skaar EP. The Immune Protein Calprotectin Impacts Clostridioides difficile Metabolism through Zinc Limitation. Mbio. 10. PMID 31744916 DOI: 10.1128/Mbio.02289-19 |
0.771 |
|
| 2019 |
Bennett MR, Dong J, Bombardi RG, Soto C, Parrington HM, Nargi RS, Schoeder CT, Nagel MB, Schey KL, Meiler J, Skaar EP, Crowe JE. Human Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis. Mbio. 10. PMID 31641091 DOI: 10.1128/Mbio.02473-19 |
0.516 |
|
| 2019 |
Perry WJ, Spraggins JM, Sheldon JR, Grunenwald CM, Heinrichs DE, Cassat JE, Skaar EP, Caprioli RM. exhibits heterogeneous siderophore production within the vertebrate host. Proceedings of the National Academy of Sciences of the United States of America. PMID 31611408 DOI: 10.1073/Pnas.1913991116 |
0.824 |
|
| 2019 |
Beavers WN, Monteith AJ, Amarnath V, Mernaugh RL, Roberts LJ, Chazin WJ, Davies SS, Skaar EP. Arachidonic Acid Kills Staphylococcus aureus through a Lipid Peroxidation Mechanism. Mbio. 10. PMID 31575763 DOI: 10.1128/Mbio.01333-19 |
0.76 |
|
| 2019 |
Hesse LE, Lonergan ZR, Beavers WN, Skaar EP. The Znu system overcomes host-imposed nutrient zinc limitation. Infection and Immunity. PMID 31548324 DOI: 10.1128/Iai.00746-19 |
0.776 |
|
| 2019 |
Lonergan ZR, Skaar EP. Nutrient Zinc at the Host-Pathogen Interface. Trends in Biochemical Sciences. PMID 31326221 DOI: 10.1016/J.Tibs.2019.06.010 |
0.52 |
|
| 2019 |
Choby JE, Skaar EP. Staphylococcus aureus Coproporphyrinogen III Oxidase Is Required for Aerobic and Anaerobic Heme Synthesis. Msphere. 4. PMID 31292227 DOI: 10.1128/mSphere.00235-19 |
0.38 |
|
| 2019 |
Jordan MR, Wang J, Weiss A, Skaar EP, Capdevila DA, Giedroc DP. Mechanistic Insights into the Metal-Dependent Activation of Zn-Dependent Metallochaperones. Inorganic Chemistry. PMID 31247880 DOI: 10.1021/Acs.Inorgchem.9B01173 |
0.387 |
|
| 2019 |
Celis AI, Choby JE, Kentro J, Skaar EP, DuBois JL. Control of Metabolite Flux during the Final Steps of Heme b Biosynthesis in Gram-Positive Bacteria. Biochemistry. PMID 31241911 DOI: 10.1021/Acs.Biochem.9B00140 |
0.493 |
|
| 2019 |
Di Venanzio G, Flores-Mireles AL, Calix JJ, Haurat MF, Scott NE, Palmer LD, Potter RF, Hibbing ME, Friedman L, Wang B, Dantas G, Skaar EP, Hultgren SJ, Feldman MF. Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes. Nature Communications. 10: 2763. PMID 31235751 DOI: 10.1038/S41467-019-10706-Y |
0.488 |
|
| 2019 |
Zackular JP, Kirk L, Trindade BC, Skaar EP, Aronoff DM. Misoprostol protects mice against severe Clostridium difficile infection and promotes recovery of the gut microbiota after antibiotic perturbation. Anaerobe. PMID 31220605 DOI: 10.1016/J.Anaerobe.2019.06.006 |
0.472 |
|
| 2019 |
Luna BM, Ershova K, Yan J, Ulhaq A, Nielsen TB, Hsieh S, Pantapalangkoor P, Vanscoy B, Ambrose P, Rudin S, Hujer K, Bonomo RA, Actis L, Skaar EP, Spellberg B. Adjunctive transferrin to reduce the emergence of antibiotic resistance in Gram-negative bacteria. The Journal of Antimicrobial Chemotherapy. PMID 31170282 DOI: 10.1093/Jac/Dkz225 |
0.545 |
|
| 2019 |
Ryan DJ, Patterson NH, Putnam NE, Wilde AD, Weiss A, Perry WJ, Cassat JE, Skaar EP, Caprioli RM, Spraggins JM. MicroLESA: Integrating Autofluorescence Microscopy, In Situ Micro-Digestions, and Liquid Extraction Surface Analysis for High Spatial Resolution Targeted Proteomic Studies. Analytical Chemistry. PMID 31149808 DOI: 10.1021/Acs.Analchem.8B05889 |
0.426 |
|
| 2019 |
Blank B, Talukder P, Muir R, Green E, Skaar EP, Renslo AR. Targeting Mobilization of Ferrous Iron in Pseudomonas aeruginosa Infection with an Iron(II)-Caged LpxC Inhibitor. Acs Infectious Diseases. PMID 31140267 DOI: 10.1021/Acsinfecdis.9B00057 |
0.542 |
|
| 2019 |
Noto JM, Zackular JP, Varga MG, Delgado A, Romero-Gallo J, Scholz MB, Piazuelo MB, Skaar EP, Peek RM. Modification of the Gastric Mucosal Microbiota by a Strain-Specific Helicobacter pylori Oncoprotein and Carcinogenic Histologic Phenotype. Mbio. 10. PMID 31138752 DOI: 10.1128/Mbio.00955-19 |
0.434 |
|
| 2019 |
Sheldon JR, Skaar EP. Metals as phagocyte antimicrobial effectors. Current Opinion in Immunology. 60: 1-9. PMID 31063946 DOI: 10.1016/J.Coi.2019.04.002 |
0.502 |
|
| 2019 |
Childress ES, Garrison AT, Sheldon JR, Skaar EP, Lindsley CW. Total synthesis of hinduchelins A-D, stereochemical revision of hinduchelin A, and biological evaluation of natural and unnatural analogs. The Journal of Organic Chemistry. PMID 31039303 DOI: 10.1021/Acs.Joc.9B00391 |
0.403 |
|
| 2019 |
Palmer LD, Jordan AT, Maloney KN, Farrow MA, Gutierrez DB, Gant-Branum R, Burns WJ, Romer CE, Tsui T, Allen JL, Beavers WN, Nei YW, Sherrod SD, Lacy DB, Norris JL, ... ... Skaar EP, et al. Zinc intoxication induces ferroptosis in A549 human lung cells. Metallomics : Integrated Biometal Science. PMID 30968088 DOI: 10.1039/C8Mt00360B |
0.75 |
|
| 2019 |
Palmer LD, Maloney KN, Boyd KL, Goleniewska AK, Toki S, Maxwell CN, Chazin WJ, Peebles RS, Newcomb DC, Skaar EP. The Innate Immune Protein S100A9 Protects from Th2-Mediated Allergic Airway Inflammation. American Journal of Respiratory Cell and Molecular Biology. PMID 30943376 DOI: 10.1165/Rcmb.2018-0217Oc |
0.386 |
|
| 2019 |
Wang J, Lonergan ZR, Gonzalez-Gutierrez G, Nairn BL, Maxwell CN, Zhang Y, Andreini C, Karty JA, Chazin WJ, Trinidad JC, Skaar EP, Giedroc DP. Multi-metal Restriction by Calprotectin Impacts De Novo Flavin Biosynthesis in Acinetobacter baumannii. Cell Chemical Biology. PMID 30905682 DOI: 10.1016/J.Chembiol.2019.02.011 |
0.477 |
|
| 2019 |
Palmer LD, Skaar EP. Cuts Both Ways: Proteases Modulate Virulence of Enterohemorrhagic . Mbio. 10. PMID 30808700 DOI: 10.1128/Mbio.00115-19 |
0.418 |
|
| 2019 |
Grunenwald CM, Choby JE, Juttukonda LJ, Beavers WN, Weiss A, Torres VJ, Skaar EP. Manganese Detoxification by MntE Is Critical for Resistance to Oxidative Stress and Virulence of . Mbio. 10. PMID 30808698 DOI: 10.1128/Mbio.02915-18 |
0.808 |
|
| 2019 |
Palmer LD, Green ER, Sheldon JR, Skaar EP. Assessing Acinetobacter baumannii Virulence and Persistence in a Murine Model of Lung Infection. Methods in Molecular Biology (Clifton, N.J.). 1946: 289-305. PMID 30798564 DOI: 10.1007/978-1-4939-9118-1_26 |
0.459 |
|
| 2019 |
Lonergan ZR, Nairn BL, Wang J, Hsu YP, Hesse LE, Beavers WN, Chazin WJ, Trinidad JC, VanNieuwenhze MS, Giedroc DP, Skaar EP. An Acinetobacter baumannii, Zinc-Regulated Peptidase Maintains Cell Wall Integrity during Immune-Mediated Nutrient Sequestration. Cell Reports. 26: 2009-2018.e6. PMID 30784584 DOI: 10.1016/J.Celrep.2019.01.089 |
0.777 |
|
| 2019 |
Ambrose PG, VanScoy BD, Luna BM, Yan J, Ulhaq A, Nielsen T, Rudin S, Hujer K, Bonomo R, Actis L, Skaar E, Spellberg B. Apotransferrin in Combination with Ciprofloxacin Slows Bacterial Replication, Prevents Resistance Amplification, and Increases Antimicrobial Regimen Effect. Antimicrobial Agents and Chemotherapy. PMID 30782989 DOI: 10.1128/Aac.00112-19 |
0.387 |
|
| 2019 |
Choby JE, Monteith AJ, Himmel LE, Margaritis P, Shirey-Rice JK, Pruijssers A, Jerome RN, Pulley J, Skaar EP. PheWAS uncovers a pathological role of coagulation Factor X during infection. Infection and Immunity. PMID 30782860 DOI: 10.1128/Iai.00031-19 |
0.443 |
|
| 2019 |
Kozlyuk N, Monteith AJ, Garcia V, Damo SM, Skaar EP, Chazin WJ. S100 Proteins in the Innate Immune Response to Pathogens. Methods in Molecular Biology (Clifton, N.J.). 1929: 275-290. PMID 30710280 DOI: 10.1007/978-1-4939-9030-6_18 |
0.473 |
|
| 2019 |
Williams JC, Sheldon JR, Imlay HD, Dutter BF, Draelos MM, Skaar EP, Sulikowski GA. Synthesis of the Siderophore Coelichelin and Its Utility as a Probe in the Study of Bacterial Metal Sensing and Response. Organic Letters. PMID 30645132 DOI: 10.1021/Acs.Orglett.8B03857 |
0.485 |
|
| 2019 |
Maseda D, Zackular JP, Trindade B, Kirk L, Roxas JL, Rogers LM, Washington MK, Du L, Koyama T, Viswanathan VK, Vedantam G, Schloss PD, Crofford LJ, Skaar EP, Aronoff DM. Nonsteroidal Anti-inflammatory Drugs Alter the Microbiota and Exacerbate Colitis while Dysregulating the Inflammatory Response. Mbio. 10. PMID 30622186 DOI: 10.1128/Mbio.02282-18 |
0.465 |
|
| 2019 |
Noto JM, Zackular J, Varga MG, Romero-Gallo J, Piazuelo MB, Scholz M, Skaar EP, Peek RM. 1133 – ΑΑInduction of Gastric Dysbiosis by Carcinogenic Helicobacter Pylori is Altered by the Oncoprotein Caga and Segregates with Premalignant and Malignant Histologic Phenotypes Gastroenterology. 156: S-240. DOI: 10.1016/S0016-5085(19)37400-1 |
0.323 |
|
| 2019 |
Nicholson MR, Parnell JM, Fazili I, Bloch SC, Lacy DB, Skaar EP, Edwards K. 238 – Nucleic Acid Amplification Followed by Enzyme Immunoassay Testing for Clostridium Difficile is Inadequate in Differentiating Infection Versus Colonization in Pediatric Patients Gastroenterology. 156: S-45-S-46. DOI: 10.1016/S0016-5085(19)36894-5 |
0.579 |
|
| 2018 |
Knippel RJ, Zackular JP, Moore JL, Celis AI, Weiss A, Washington MK, DuBois JL, Caprioli RM, Skaar EP. Heme sensing and detoxification by HatRT contributes to pathogenesis during Clostridium difficile infection. Plos Pathogens. 14: e1007486. PMID 30576368 DOI: 10.1371/Journal.Ppat.1007486 |
0.553 |
|
| 2018 |
Grunenwald CM, Bennett MR, Skaar EP. Nonconventional Therapeutics against . Microbiology Spectrum. 6. PMID 30547858 DOI: 10.1128/Microbiolspec.Gpp3-0047-2018 |
0.796 |
|
| 2018 |
Bennett MR, Bombardi RG, Kose N, Parrish EH, Nagel MB, Petit RA, Read TD, Schey KL, Thomsen IP, Skaar EP, Crowe JE. Human mAbs to Staphylococcus aureus IsdA Provide Protection Through Both Heme-Blocking and Fc-Mediated Mechanisms. The Journal of Infectious Diseases. PMID 30496483 DOI: 10.1093/Infdis/Jiy635 |
0.535 |
|
| 2018 |
Choby JE, Buechi HB, Farrand AJ, Skaar EP, Barber MF. Molecular Basis for the Evolution of Species-Specific Hemoglobin Capture by Staphylococcus aureus. Mbio. 9. PMID 30459189 DOI: 10.1128/Mbio.01524-18 |
0.559 |
|
| 2018 |
Juttukonda LJ, Green ER, Lonergan ZR, Heffern MC, Chang CJ, Skaar EP. OxyR regulates the transcriptional response to hydrogen peroxide. Infection and Immunity. PMID 30297527 DOI: 10.1128/Iai.00413-18 |
0.52 |
|
| 2018 |
Pishchany G, Mevers E, Ndousse-Fetter S, Horvath DJ, Paludo CR, Silva-Junior EA, Koren S, Skaar EP, Clardy J, Kolter R. Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen. Proceedings of the National Academy of Sciences of the United States of America. PMID 30228116 DOI: 10.1073/Pnas.1807613115 |
0.474 |
|
| 2018 |
Gutierrez DB, Gant-Branum RL, Romer CE, Farrow MA, Allen JL, Dahal N, Nei YW, Codreanu SG, Jordan AT, Palmer LD, Sherrod SD, McLean JA, Skaar EP, Norris JL, Caprioli RM. An integrated, high-throughput strategy for multi-omic systems level analysis. Journal of Proteome Research. PMID 30114907 DOI: 10.1021/Acs.Jproteome.8B00302 |
0.365 |
|
| 2018 |
Heilbronner S, Monk IR, Brozyna JR, Heinrichs DE, Skaar EP, Peschel A, Foster TJ. Correction: Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation. Plos Genetics. 14: e1007564. PMID 30052688 DOI: 10.1371/journal.pgen.1007564 |
0.299 |
|
| 2018 |
Lopez CA, Skaar EP. The Impact of Dietary Transition Metals on Host-Bacterial Interactions. Cell Host & Microbe. 23: 737-748. PMID 29902439 DOI: 10.1016/J.Chom.2018.05.008 |
0.496 |
|
| 2018 |
Ayala OD, Wakeman C, Pence IJ, Skaar EP, Mahadevan-Jansen A. Drug-resistant Staphylococcus aureus strains reveal distinct biochemical features with Raman microspectroscopy. Acs Infectious Diseases. PMID 29845863 DOI: 10.1021/Acsinfecdis.8B00029 |
0.75 |
|
| 2018 |
Lentz CS, Sheldon JR, Crawford LA, Cooper R, Garland M, Amieva MR, Weerapana E, Skaar EP, Bogyo M. Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP). Nature Chemical Biology. PMID 29769740 DOI: 10.1038/S41589-018-0060-1 |
0.554 |
|
| 2018 |
Cassat JE, Moore JL, Wilson KJ, Stark Z, Prentice BM, Van de Plas R, Perry WJ, Zhang Y, Virostko J, Colvin DC, Rose KL, Judd AM, Reyzer ML, Spraggins JM, Grunenwald CM, ... ... Skaar EP, et al. Integrated molecular imaging reveals tissue heterogeneity driving host-pathogen interactions. Science Translational Medicine. 10. PMID 29540616 DOI: 10.1126/Scitranslmed.Aan6361 |
0.795 |
|
| 2018 |
Zackular JP, Skaar EP. The role of zinc and nutritional immunity in Clostridium difficile infection. Gut Microbes. 0. PMID 29533126 DOI: 10.1080/19490976.2018.1448354 |
0.543 |
|
| 2018 |
Choby JE, Grunenwald CM, Celis AI, Gerdes SY, DuBois JL, Skaar EP.
HemX Modulates Glutamyl-tRNA Reductase Abundance To Regulate Heme Biosynthesis. Mbio. 9. PMID 29437922 DOI: 10.1128/Mbio.02287-17 |
0.826 |
|
| 2018 |
Lojek LJ, Farrand AJ, Weiss A, Skaar EP. Fur regulation of Staphylococcus aureus heme oxygenases is required for heme homeostasis. International Journal of Medical Microbiology : Ijmm. PMID 29409696 DOI: 10.1016/J.Ijmm.2018.01.009 |
0.509 |
|
| 2017 |
Ayala OD, Wakeman CA, Pence IJ, O'Brien CM, Werkhaven JA, Skaar EP, Mahadevan-Jansen A. Characterization of bacteria causing acute otitis media using Raman microspectroscopy. Analytical Methods : Advancing Methods and Applications. 9: 1864-1871. PMID 34858522 DOI: 10.1039/c7ay00128b |
0.343 |
|
| 2017 |
Lopez CA, Skaar EP. Crossed Wires: Interspecies Interference Blocks Pathogen Colonization. Cell Host & Microbe. 22: 721-723. PMID 29241035 DOI: 10.1016/J.Chom.2017.11.016 |
0.468 |
|
| 2017 |
Aron AT, Heffern MC, Lonergan ZR, Vander Wal MN, Blank BR, Spangler B, Zhang Y, Park HM, Stahl A, Renslo AR, Skaar EP, Chang CJ. In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter baumannii infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 29138321 DOI: 10.1073/Pnas.1708747114 |
0.49 |
|
| 2017 |
Kinsella RL, Lopez J, Palmer LD, Salinas ND, Skaar EP, Tolia NH, Feldman MF. Defining the interaction of the protease CpaA with its type II secretion-chaperone CpaB and its contribution to virulence in Acinetobacter species. The Journal of Biological Chemistry. PMID 28982978 DOI: 10.1074/Jbc.M117.808394 |
0.44 |
|
| 2017 |
Juttukonda LJ, Berends ETM, Zackular JP, Moore JL, Stier MT, Zhang Y, Schmitz JE, Beavers WN, Wijers CD, Gilston BA, Kehl-Fie TE, Atkinson J, Washington MK, Peebles RS, Chazin WJ, ... ... Skaar EP, et al. Dietary Manganese Promotes Staphylococcal Infection of the Heart. Cell Host & Microbe. PMID 28943329 DOI: 10.1016/J.Chom.2017.08.009 |
0.79 |
|
| 2017 |
Peng H, Zhang Y, Palmer LD, Kehl-Fie TE, Skaar EP, Trinidad JC, Giedroc DP. Hydrogen sulfide (H2S) and reactive sulfur species (RSS) impact proteome S-sulfhydration and global virulence regulation in Staphylococcus aureus. Acs Infectious Diseases. PMID 28850209 DOI: 10.1021/Acsinfecdis.7B00090 |
0.485 |
|
| 2017 |
Lojek LJ, Farrand AJ, Wisecaver JH, Blaby-Haas CE, Michel BW, Merchant SS, Rokas A, Skaar EP. Chlamydomonas reinhardtii LFO1 Is an IsdG Family Heme Oxygenase. Msphere. 2. PMID 28815214 DOI: 10.1128/mSphere.00176-17 |
0.295 |
|
| 2017 |
Surdel MC, Horvath DJ, Lojek LJ, Fullen AR, Simpson J, Dutter BF, Salleng KJ, Ford JB, Jenkins JL, Nagarajan R, Teixeira PL, Albertolle M, Georgiev IS, Jansen ED, Sulikowski GA, ... ... Skaar EP, et al. Antibacterial photosensitization through activation of coproporphyrinogen oxidase. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739897 DOI: 10.1073/Pnas.1700469114 |
0.639 |
|
| 2017 |
Peng H, Shen J, Edmonds KA, Luebke JL, Hickey AK, Palmer LD, Chang FJ, Bruce KA, Kehl-Fie TE, Skaar EP, Giedroc DP. Sulfide Homeostasis and Nitroxyl Intersect via Formation of Reactive Sulfur Species in Staphylococcus aureus. Msphere. 2. PMID 28656172 DOI: 10.1128/mSphere.00082-17 |
0.427 |
|
| 2017 |
Noto MJ, Burns WJ, Beavers WN, Skaar EP. Mechanisms of pyocyanin toxicity and genetic determinants of resistance in Staphylococcus aureus. Journal of Bacteriology. PMID 28607159 DOI: 10.1128/Jb.00221-17 |
0.763 |
|
| 2017 |
Pulley JM, Shirey-Rice JK, Lavieri RR, Jerome RN, Zaleski NM, Aronoff DM, Bastarache L, Niu X, Holroyd KJ, Roden DM, Skaar EP, Niswender CM, Marnett LJ, Lindsley CW, Ekstrom LB, et al. Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics. Assay and Drug Development Technologies. PMID 28379727 DOI: 10.1089/Adt.2016.772 |
0.478 |
|
| 2017 |
Garcia YM, Barwinska-Sendra A, Tarrant E, Skaar EP, Waldron KJ, Kehl-Fie TE. A Superoxide Dismutase Capable of Functioning with Iron or Manganese Promotes the Resistance of Staphylococcus aureus to Calprotectin and Nutritional Immunity. Plos Pathogens. 13: e1006125. PMID 28103306 DOI: 10.1371/Journal.Ppat.1006125 |
0.556 |
|
| 2017 |
Norris JL, Farrow MA, Gutierrez DB, Palmer LD, Muszynski N, Sherrod SD, Pino JC, Allen JL, Spraggins JM, Lubbock AL, Jordan AT, Burns W, Poland JC, Romer CE, Manier ML, ... ... Skaar EP, et al. An integrated, high-throughput, multi-omics platform enables data-driven construction of cellular responses and reveals global drug mechanisms of action. Journal of Proteome Research. PMID 28088864 DOI: 10.1021/Acs.Jproteome.6B01004 |
0.574 |
|
| 2017 |
Noto MJ, Becker KW, Boyd KL, Schmidt AM, Skaar EP. RAGE-mediated suppression of IL-10 results in enhanced mortality in a murine model of Acinetobacter baumannii sepsis. Infection and Immunity. PMID 28052995 DOI: 10.1128/Iai.00954-16 |
0.466 |
|
| 2017 |
Ayala OD, Wakeman CA, Pence IJ, O'Brien CM, Werkhaven JA, Skaar EP, Mahadevan-Jansen A. Characterization of bacteria causing acute otitis media using Raman microspectroscopy Analytical Methods. 9: 1864-1871. DOI: 10.1039/C7Ay00128B |
0.725 |
|
| 2016 |
Zackular JP, Moore JL, Jordan AT, Juttukonda LJ, Noto MJ, Nicholson MR, Crews JD, Semler MW, Zhang Y, Ware LB, Washington MK, Chazin WJ, Caprioli RM, Skaar EP. Erratum: Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection. Nature Medicine. 22: 1502. PMID 27923021 DOI: 10.1038/nm1216-1502d |
0.39 |
|
| 2016 |
Choby JE, Mike LA, Mashruwala AA, Dutter BF, Dunman PM, Sulikowski GA, Boyd JM, Skaar EP. A Small-Molecule Inhibitor of Iron-Sulfur Cluster Assembly Uncovers a Link between Virulence Regulation and Metabolism in Staphylococcus aureus. Cell Chemical Biology. PMID 27773628 DOI: 10.1016/J.Chembiol.2016.09.012 |
0.458 |
|
| 2016 |
Varga MG, Piazuelo MB, Romero-Gallo J, Delgado AG, Suarez G, Whitaker ME, Krishna US, Patel RV, Skaar EP, Wilson KT, Algood HM, Peek RM. TLR9 Activation Suppresses Inflammation in Response to Helicobacter pylori Infection. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00175.2016. PMID 27758771 DOI: 10.1152/Ajpgi.00175.2016 |
0.458 |
|
| 2016 |
Juttukonda LJ, Chazin WJ, Skaar EP. Acinetobacter baumannii Coordinates Urea Metabolism with Metal Import To Resist Host-Mediated Metal Limitation. Mbio. 7. PMID 27677795 DOI: 10.1128/Mbio.01475-16 |
0.54 |
|
| 2016 |
Zackular JP, Moore JL, Jordan AT, Juttukonda LJ, Noto MJ, Nicholson MR, Crews JD, Semler MW, Zhang Y, Ware LB, Washington MK, Chazin WJ, Caprioli RM, Skaar EP. Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection. Nature Medicine. PMID 27668938 DOI: 10.1038/Nm.4174 |
0.528 |
|
| 2016 |
Surdel MC, Dutter BF, Sulikowski GA, Skaar EP. Bacterial Nitric Oxide Synthase Is Required for the Staphylococcus aureus Response to Heme Stress. Acs Infectious Diseases. 2: 572-8. PMID 27626297 DOI: 10.1021/Acsinfecdis.6B00081 |
0.507 |
|
| 2016 |
Palmer LD, Skaar EP. Transition Metals and Virulence in Bacteria. Annual Review of Genetics. PMID 27617971 DOI: 10.1146/Annurev-Genet-120215-035146 |
0.454 |
|
| 2016 |
Heilbronner S, Monk IR, Brozyna JR, Heinrichs DE, Skaar EP, Peschel A, Foster TJ. Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation. Plos Genetics. 12: e1006246. PMID 27575058 DOI: 10.1371/Journal.Pgen.1006246 |
0.545 |
|
| 2016 |
Gilston BA, Skaar EP, Chazin WJ. Binding of transition metals to S100 proteins. Science China. Life Sciences. PMID 27430886 DOI: 10.1007/S11427-016-5088-4 |
0.408 |
|
| 2016 |
Hammer ND, Schurig-Briccio LA, Gerdes SY, Gennis RB, Skaar EP. CtaM Is Required for Menaquinol Oxidase aa3 Function in Staphylococcus aureus. Mbio. 7. PMID 27406563 DOI: 10.1128/Mbio.00823-16 |
0.508 |
|
| 2016 |
Beavers WN, Skaar EP. Neutrophil generated oxidative stress and protein damage in Staphylococcus aureus. Pathogens and Disease. PMID 27354296 DOI: 10.1093/Femspd/Ftw060 |
0.753 |
|
| 2016 |
Hendrix AS, Spoonmore TJ, Wilde AD, Putnam NE, Hammer ND, Snyder DJ, Guelcher SA, Skaar EP, Cassat JE. Repurposing the nonsteroidal anti-inflammatory drug diflunisal as an osteoprotective, anti-virulence therapy for Staphylococcus aureus osteomyelitis. Antimicrobial Agents and Chemotherapy. PMID 27324764 DOI: 10.1128/Aac.00834-16 |
0.434 |
|
| 2016 |
Wakeman CA, Moore JL, Noto MJ, Zhang Y, Singleton MD, Prentice BM, Gilston BA, Doster RS, Gaddy JA, Chazin WJ, Caprioli RM, Skaar EP. The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction. Nature Communications. 7: 11951. PMID 27301800 DOI: 10.1038/Ncomms11951 |
0.807 |
|
| 2016 |
Nairn BL, Lonergan ZR, Wang J, Braymer JJ, Zhang Y, Calcutt MW, Lisher JP, Gilston BA, Chazin WJ, de Crécy-Lagard V, Giedroc DP, Skaar EP. The Response of Acinetobacter baumannii to Zinc Starvation. Cell Host & Microbe. 19: 826-836. PMID 27281572 DOI: 10.1016/J.Chom.2016.05.007 |
0.486 |
|
| 2016 |
Diaz-Ochoa VE, Lam D, Lee CS, Klaus S, Behnsen J, Liu JZ, Chim N, Nuccio SP, Rathi SG, Mastroianni JR, Edwards RA, Jacobo CM, Cerasi M, Battistoni A, Ouellette AJ, ... ... Skaar EP, et al. Salmonella Mitigates Oxidative Stress and Thrives in the Inflamed Gut by Evading Calprotectin-Mediated Manganese Sequestration. Cell Host & Microbe. 19: 814-825. PMID 27281571 DOI: 10.1016/J.Chom.2016.05.005 |
0.532 |
|
| 2016 |
Varga MG, Shaffer CL, Sierra JC, Suarez G, Piazuelo MB, Whitaker ME, Romero-Gallo J, Krishna US, Delgado A, Gomez MA, Good JA, Almqvist F, Skaar EP, Correa P, Wilson KT, et al. Pathogenic Helicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system. Oncogene. PMID 27157617 DOI: 10.1038/Onc.2016.158 |
0.422 |
|
| 2016 |
Spraggins JM, Rizzo DG, Moore JL, Noto MJ, Skaar EP, Caprioli RM. Next-generation technologies for spatial proteomics: Integrating ultra-high speed MALDI-TOF and high mass resolution MALDI FTICR imaging mass spectrometry for protein analysis. Proteomics. PMID 27060368 DOI: 10.1002/Pmic.201600003 |
0.369 |
|
| 2016 |
Choby JE, Skaar EP. Heme Synthesis and Acquisition in Bacterial Pathogens. Journal of Molecular Biology. PMID 27019298 DOI: 10.1016/J.Jmb.2016.03.018 |
0.556 |
|
| 2016 |
Dutter BF, Mike LA, Reid PR, Chong KM, Ramos-Hunter SJ, Skaar EP, Sulikowski GA. Decoupling Activation of Heme Biosynthesis from Anaerobic Toxicity in a Molecule Active in Staphylococcus aureus. Acs Chemical Biology. PMID 26890615 DOI: 10.1021/Acschembio.5B00934 |
0.418 |
|
| 2016 |
Harding CM, Kinsella RL, Palmer LD, Skaar EP, Feldman MF. Medically Relevant Acinetobacter Species Require a Type II Secretion System and Specific Membrane-Associated Chaperones for the Export of Multiple Substrates and Full Virulence. Plos Pathogens. 12: e1005391. PMID 26764912 DOI: 10.1371/Journal.Ppat.1005391 |
0.471 |
|
| 2016 |
Harding CM, Kinsella RL, Palmer LD, Skaar EP, Feldman MF. Medically Relevant Acinetobacter Species Require a Type II Secretion System and Specific Membrane-Associated Chaperones for the Export of Multiple Substrates and Full Virulence Plos Pathogens. 12. DOI: 10.1371/journal.ppat.1005391 |
0.25 |
|
| 2016 |
Ayala OD, Wakeman CA, Skaar EP, Mahadevan-Jansen A. Identification of bacteria causing acute otitis media using Raman microspectroscopy Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9704. DOI: 10.1117/12.2213563 |
0.754 |
|
| 2016 |
Hammer ND, Schurig-Briccio LA, Gerdes SY, Gennis RB, Skaar EP. QoxABCD from Staphylococcus aureus can be assembled as either an aa3 -type or bo3 -type menaquinol oxidase and requires CtaM to function Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1857: e86. DOI: 10.1016/J.Bbabio.2016.04.209 |
0.363 |
|
| 2015 |
Wilde AD, Snyder DJ, Putnam NE, Valentino MD, Hammer ND, Lonergan ZR, Hinger SA, Aysanoa EE, Blanchard C, Dunman PM, Wasserman GA, Chen J, Shopsin B, Gilmore MS, Skaar EP, et al. Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection. Plos Pathogens. 11: e1005341. PMID 26684646 DOI: 10.1371/Journal.Ppat.1005341 |
0.541 |
|
| 2015 |
Gaddy JA, Radin JN, Cullen TW, Chazin WJ, Skaar EP, Trent MS, Algood HM. Helicobacter pylori Resists the Antimicrobial Activity of Calprotectin via Lipid A Modification and Associated Biofilm Formation. Mbio. 6: e01349-15. PMID 26646009 DOI: 10.1128/Mbio.01349-15 |
0.67 |
|
| 2015 |
Clark HL, Jhingran A, Sun Y, Vareechon C, de Jesus Carrion S, Skaar EP, Chazin WJ, Calera JA, Hohl TM, Pearlman E. Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits Extracellular Aspergillus fumigatus Hyphal Growth and Corneal Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26582948 DOI: 10.4049/Jimmunol.1502037 |
0.499 |
|
| 2015 |
Streit BR, Kant R, Tokmina-Lukaszewska M, Celis AI, Machovina MM, Skaar EP, Bothner B, DuBois JL. Time-resolved studies of IsdG identify molecular signposts along the non-canonical heme oxygenase pathway. The Journal of Biological Chemistry. PMID 26534961 DOI: 10.1074/Jbc.M115.666560 |
0.46 |
|
| 2015 |
Noto MJ, Boyd KL, Burns WJ, Varga MG, Peek RM, Skaar EP. Toll-Like Receptor 9 Contributes to Defense against Acinetobacter baumannii Infection. Infection and Immunity. 83: 4134-41. PMID 26238713 DOI: 10.1128/Iai.00410-15 |
0.489 |
|
| 2015 |
Cho H, Jeong DW, Liu Q, Yeo WS, Vogl T, Skaar EP, Chazin WJ, Bae T. Calprotectin Increases the Activity of the SaeRS Two Component System and Murine Mortality during Staphylococcus aureus Infections. Plos Pathogens. 11: e1005026. PMID 26147796 DOI: 10.1371/Journal.Ppat.1005026 |
0.679 |
|
| 2015 |
Rosario-Cruz Z, Chahal HK, Mike LA, Skaar EP, Boyd JM. Bacillithiol has a role in Fe-S cluster biogenesis in Staphylococcus aureus. Molecular Microbiology. PMID 26135358 DOI: 10.1111/Mmi.13115 |
0.424 |
|
| 2015 |
Farrand AJ, Haley KP, Lareau NM, Heilbronner S, McLean JA, Foster T, Skaar EP. An Iron-Regulated Autolysin Remodels the Cell Wall To Facilitate Heme Acquisition in Staphylococcus lugdunensis. Infection and Immunity. 83: 3578-89. PMID 26123800 DOI: 10.1128/Iai.00397-15 |
0.79 |
|
| 2015 |
Zackular JP, Chazin WJ, Skaar EP. Nutritional Immunity: S100 Proteins at the Host-Pathogen Interface. The Journal of Biological Chemistry. 290: 18991-8. PMID 26055713 DOI: 10.1074/Jbc.R115.645085 |
0.493 |
|
| 2015 |
Skaar EP, Raffatellu M. Metals in infectious diseases and nutritional immunity. Metallomics : Integrated Biometal Science. 7: 926-8. PMID 26017093 DOI: 10.1039/C5Mt90021B |
0.392 |
|
| 2015 |
Haley KP, Delgado AG, Piazuelo MB, Mortensen BL, Correa P, Damo SM, Chazin WJ, Skaar EP, Gaddy JA. The Human Antimicrobial Protein Calgranulin C Participates in Control of Helicobacter pylori Growth and Regulation of Virulence. Infection and Immunity. 83: 2944-56. PMID 25964473 DOI: 10.1128/Iai.00544-15 |
0.817 |
|
| 2015 |
Spraggins JM, Rizzo DG, Moore JL, Rose KL, Hammer ND, Skaar EP, Caprioli RM. MALDI FTICR IMS of Intact Proteins: Using Mass Accuracy to Link Protein Images with Proteomics Data. Journal of the American Society For Mass Spectrometry. 26: 974-85. PMID 25904064 DOI: 10.1007/S13361-015-1147-5 |
0.395 |
|
| 2015 |
Messad N, Prajsnar TK, Lina G, O'Callaghan D, Foster SJ, Renshaw SA, Skaar EP, Bes M, Dunyach-Remy C, Vandenesch F, Sotto A, Lavigne JP. Existence of a Colonizing Staphylococcus aureus Strain Isolated in Diabetic Foot Ulcers. Diabetes. 64: 2991-5. PMID 25901094 DOI: 10.2337/Db15-0031 |
0.489 |
|
| 2015 |
Juttukonda LJ, Skaar EP. Manganese homeostasis and utilization in pathogenic bacteria. Molecular Microbiology. 97: 216-28. PMID 25898914 DOI: 10.1111/Mmi.13034 |
0.522 |
|
| 2015 |
D'Orazio M, Mastropasqua MC, Cerasi M, Pacello F, Consalvo A, Chirullo B, Mortensen B, Skaar EP, Ciavardelli D, Pasquali P, Battistoni A. The capability of Pseudomonas aeruginosa to recruit zinc under conditions of limited metal availability is affected by inactivation of the ZnuABC transporter. Metallomics : Integrated Biometal Science. 7: 1023-35. PMID 25751674 DOI: 10.1039/C5Mt00017C |
0.538 |
|
| 2015 |
Farrand AJ, Friedman DB, Reniere ML, Ingmer H, Frees D, Skaar EP. Proteomic analyses of iron-responsive, Clp-dependent changes in Staphylococcus aureus. Pathogens and Disease. 73. PMID 25743475 DOI: 10.1093/Femspd/Ftv004 |
0.552 |
|
| 2015 |
Floyd KA, Moore JL, Eberly AR, Good JA, Shaffer CL, Zaver H, Almqvist F, Skaar EP, Caprioli RM, Hadjifrangiskou M. Adhesive fiber stratification in uropathogenic Escherichia coli biofilms unveils oxygen-mediated control of type 1 pili. Plos Pathogens. 11: e1004697. PMID 25738819 DOI: 10.1371/Journal.Ppat.1004697 |
0.495 |
|
| 2015 |
Mashruwala AA, Pang YY, Rosario-Cruz Z, Chahal HK, Benson MA, Mike LA, Skaar EP, Torres VJ, Nauseef WM, Boyd JM. Nfu facilitates the maturation of iron-sulfur proteins and participates in virulence in Staphylococcus aureus. Molecular Microbiology. 95: 383-409. PMID 25388433 DOI: 10.1111/Mmi.12860 |
0.643 |
|
| 2014 |
Gaddy JA, Radin JN, Loh JT, Piazuelo MB, Kehl-Fie TE, Delgado AG, Ilca FT, Peek RM, Cover TL, Chazin WJ, Skaar EP, Scott Algood HM. The host protein calprotectin modulates the Helicobacter pylori cag type IV secretion system via zinc sequestration. Plos Pathogens. 10: e1004450. PMID 25330071 DOI: 10.1371/Journal.Ppat.1004450 |
0.741 |
|
| 2014 |
Luebke JL, Shen J, Bruce KE, Kehl-Fie TE, Peng H, Skaar EP, Giedroc DP. The CsoR-like sulfurtransferase repressor (CstR) is a persulfide sensor in Staphylococcus aureus. Molecular Microbiology. 94: 1343-60. PMID 25318663 DOI: 10.1111/Mmi.12835 |
0.459 |
|
| 2014 |
Hammer ND, Cassat JE, Noto MJ, Lojek LJ, Chadha AD, Schmitz JE, Creech CB, Skaar EP. Inter- and intraspecies metabolite exchange promotes virulence of antibiotic-resistant Staphylococcus aureus. Cell Host & Microbe. 16: 531-7. PMID 25299336 DOI: 10.1016/J.Chom.2014.09.002 |
0.468 |
|
| 2014 |
Becker KW, Skaar EP. Metal limitation and toxicity at the interface between host and pathogen. Fems Microbiology Reviews. 38: 1235-49. PMID 25211180 DOI: 10.1111/1574-6976.12087 |
0.471 |
|
| 2014 |
Achouiti A, Vogl T, Endeman H, Mortensen BL, Laterre PF, Wittebole X, van Zoelen MA, Zhang Y, Hoogerwerf JJ, Florquin S, Schultz MJ, Grutters JC, Biesma DH, Roth J, Skaar EP, et al. Myeloid-related protein-8/14 facilitates bacterial growth during pneumococcal pneumonia. Thorax. 69: 1034-42. PMID 25179663 DOI: 10.1136/Thoraxjnl-2014-205668 |
0.521 |
|
| 2014 |
Moore JL, Caprioli RM, Skaar EP. Advanced mass spectrometry technologies for the study of microbial pathogenesis. Current Opinion in Microbiology. 19: 45-51. PMID 24997399 DOI: 10.1016/J.Mib.2014.05.023 |
0.418 |
|
| 2014 |
Mortensen BL, Rathi S, Chazin WJ, Skaar EP. Acinetobacter baumannii response to host-mediated zinc limitation requires the transcriptional regulator Zur. Journal of Bacteriology. 196: 2616-26. PMID 24816603 DOI: 10.1128/Jb.01650-14 |
0.547 |
|
| 2014 |
Mike LA, Choby JE, Brinkman PR, Olive LQ, Dutter BF, Ivan SJ, Gibbs CM, Sulikowski GA, Stauff DL, Skaar EP. Two-component system cross-regulation integrates Bacillus anthracis response to heme and cell envelope stress. Plos Pathogens. 10: e1004044. PMID 24675902 DOI: 10.1371/Journal.Ppat.1004044 |
0.428 |
|
| 2014 |
Thompson MK, Keithly ME, Goodman MC, Hammer ND, Cook PD, Jagessar KL, Harp J, Skaar EP, Armstrong RN. Structure and function of the genomically encoded fosfomycin resistance enzyme, FosB, from Staphylococcus aureus. Biochemistry. 53: 755-65. PMID 24447055 DOI: 10.1021/bi4015852 |
0.465 |
|
| 2014 |
Lin L, Pantapalangkoor P, Tan B, Bruhn KW, Ho T, Nielsen T, Skaar EP, Zhang Y, Bai R, Wang A, Doherty TM, Spellberg B. Transferrin iron starvation therapy for lethal bacterial and fungal infections. The Journal of Infectious Diseases. 210: 254-64. PMID 24446527 DOI: 10.1093/Infdis/Jiu049 |
0.567 |
|
| 2014 |
Wakeman CA, Stauff DL, Zhang Y, Skaar EP. Differential activation of Staphylococcus aureus heme detoxification machinery by heme analogues. Journal of Bacteriology. 196: 1335-42. PMID 24443529 DOI: 10.1128/Jb.01067-13 |
0.777 |
|
| 2014 |
Pishchany G, Sheldon JR, Dickson CF, Alam MT, Read TD, Gell DA, Heinrichs DE, Skaar EP. IsdB-dependent hemoglobin binding is required for acquisition of heme by Staphylococcus aureus. The Journal of Infectious Diseases. 209: 1764-72. PMID 24338348 DOI: 10.1093/Infdis/Jit817 |
0.529 |
|
| 2014 |
Moore JL, Becker KW, Nicklay JJ, Boyd KL, Skaar EP, Caprioli RM. Imaging mass spectrometry for assessing temporal proteomics: analysis of calprotectin in Acinetobacter baumannii pulmonary infection. Proteomics. 14: 820-8. PMID 23754577 DOI: 10.1002/Pmic.201300046 |
0.501 |
|
| 2013 |
Mortensen BL, Skaar EP. The contribution of nutrient metal acquisition and metabolism to Acinetobacter baumannii survival within the host. Frontiers in Cellular and Infection Microbiology. 3: 95. PMID 24377089 DOI: 10.3389/Fcimb.2013.00095 |
0.519 |
|
| 2013 |
Cassat JE, Skaar EP. Recent advances in experimental models of osteomyelitis. Expert Review of Anti-Infective Therapy. 11: 1263-5. PMID 24215241 DOI: 10.1586/14787210.2013.858600 |
0.386 |
|
| 2013 |
Hood MI, Uzhachenko R, Boyd K, Skaar EP, Ivanova AV. Loss of mitochondrial protein Fus1 augments host resistance to Acinetobacter baumannii infection. Infection and Immunity. 81: 4461-9. PMID 24042119 DOI: 10.1128/Iai.00771-13 |
0.493 |
|
| 2013 |
Farrand AJ, Reniere ML, Ingmer H, Frees D, Skaar EP. Regulation of host hemoglobin binding by the Staphylococcus aureus Clp proteolytic system. Journal of Bacteriology. 195: 5041-50. PMID 23995637 DOI: 10.1128/Jb.00505-13 |
0.587 |
|
| 2013 |
Hammer ND, Reniere ML, Cassat JE, Zhang Y, Hirsch AO, Hood MI, Skaar EP. Two heme-dependent terminal oxidases power Staphylococcus aureus organ-specific colonization of the vertebrate host Mbio. 4. PMID 23900169 DOI: 10.1128/Mbio.00241-13 |
0.551 |
|
| 2013 |
Attia AS, Cassat JE, Aranmolate SO, Zimmerman LJ, Boyd KL, Skaar EP. Analysis of the Staphylococcus aureus abscess proteome identifies antimicrobial host proteins and bacterial stress responses at the host-pathogen interface. Pathogens and Disease. PMID 23847107 DOI: 10.1111/2049-632X.12063 |
0.533 |
|
| 2013 |
Kehl-Fie TE, Zhang Y, Moore JL, Farrand AJ, Hood MI, Rathi S, Chazin WJ, Caprioli RM, Skaar EP. MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotectin for nutrient manganese. Infection and Immunity. 81: 3395-405. PMID 23817615 DOI: 10.1128/Iai.00420-13 |
0.557 |
|
| 2013 |
Cassat JE, Hammer ND, Campbell JP, Benson MA, Perrien DS, Mrak LN, Smeltzer MS, Torres VJ, Skaar EP. A secreted bacterial protease tailors the Staphylococcus aureus virulence repertoire to modulate bone remodeling during osteomyelitis. Cell Host & Microbe. 13: 759-72. PMID 23768499 DOI: 10.1016/J.Chom.2013.05.003 |
0.622 |
|
| 2013 |
Mayfield JA, Hammer ND, Kurker RC, Chen TK, Ojha S, Skaar EP, DuBois JL. The chlorite dismutase (HemQ) from Staphylococcus aureus has a redox-sensitive heme and is associated with the small colony variant phenotype. The Journal of Biological Chemistry. 288: 23488-504. PMID 23737523 DOI: 10.1074/Jbc.M112.442335 |
0.51 |
|
| 2013 |
Lee K, Boyd KL, Parekh DV, Kehl-Fie TE, Baldwin HS, Brakebusch C, Skaar EP, Boothby M, Zent R. Cdc42 promotes host defenses against fatal infection. Infection and Immunity. 81: 2714-23. PMID 23690402 DOI: 10.1128/Iai.01114-12 |
0.486 |
|
| 2013 |
Cassat JE, Skaar EP. Iron in infection and immunity. Cell Host & Microbe. 13: 509-19. PMID 23684303 DOI: 10.1016/J.Chom.2013.04.010 |
0.513 |
|
| 2013 |
Mike LA, Dutter BF, Stauff DL, Moore JL, Vitko NP, Aranmolate O, Kehl-Fie TE, Sullivan S, Reid PR, DuBois JL, Richardson AR, Caprioli RM, Sulikowski GA, Skaar EP. Activation of heme biosynthesis by a small molecule that is toxic to fermenting Staphylococcus aureus. Proceedings of the National Academy of Sciences of the United States of America. 110: 8206-11. PMID 23630262 DOI: 10.1073/Pnas.1303674110 |
0.495 |
|
| 2013 |
Hammer ND, Skaar EP. Powerful genetic resource for the study of methicillin-resistant Staphylococcus aureus. Mbio. 4. PMID 23549918 DOI: 10.1128/Mbio.00166-13 |
0.415 |
|
| 2013 |
Damo SM, Kehl-Fie TE, Sugitani N, Holt ME, Rathi S, Murphy WJ, Zhang Y, Betz C, Hench L, Fritz G, Skaar EP, Chazin WJ. Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens. Proceedings of the National Academy of Sciences of the United States of America. 110: 3841-6. PMID 23431180 DOI: 10.1073/Pnas.1220341110 |
0.526 |
|
| 2013 |
Pishchany G, Haley KP, Skaar EP. Staphylococcus aureus growth using human hemoglobin as an iron source. Journal of Visualized Experiments : Jove. PMID 23426144 DOI: 10.3791/50072 |
0.77 |
|
| 2013 |
Weber BS, Miyata ST, Iwashkiw JA, Mortensen BL, Skaar EP, Pukatzki S, Feldman MF. Genomic and functional analysis of the type VI secretion system in Acinetobacter. Plos One. 8: e55142. PMID 23365692 DOI: 10.1371/Journal.Pone.0055142 |
0.514 |
|
| 2013 |
Hood MI, Becker KW, Roux CM, Dunman PM, Skaar EP. genetic determinants of intrinsic colistin tolerance in Acinetobacter baumannii. Infection and Immunity. 81: 542-51. PMID 23230287 DOI: 10.1128/Iai.00704-12 |
0.495 |
|
| 2012 |
Hood MI, Mortensen BL, Moore JL, Zhang Y, Kehl-Fie TE, Sugitani N, Chazin WJ, Caprioli RM, Skaar EP. Identification of an Acinetobacter baumannii zinc acquisition system that facilitates resistance to calprotectin-mediated zinc sequestration. Plos Pathogens. 8: e1003068. PMID 23236280 DOI: 10.1371/Journal.Ppat.1003068 |
0.523 |
|
| 2012 |
Wakeman CA, Hammer ND, Stauff DL, Attia AS, Anzaldi LL, Dikalov SI, Calcutt MW, Skaar EP. Menaquinone biosynthesis potentiates haem toxicity in Staphylococcus aureus. Molecular Microbiology. 86: 1376-92. PMID 23043465 DOI: 10.1111/Mmi.12063 |
0.78 |
|
| 2012 |
Schmitt J, Joost I, Skaar EP, Herrmann M, Bischoff M. Haemin represses the haemolytic activity of Staphylococcus aureus in an Sae-dependent manner. Microbiology (Reading, England). 158: 2619-31. PMID 22859613 DOI: 10.1099/Mic.0.060129-0 |
0.549 |
|
| 2012 |
Hood MI, Skaar EP. Nutritional immunity: transition metals at the pathogen-host interface. Nature Reviews. Microbiology. 10: 525-37. PMID 22796883 DOI: 10.1038/Nrmicro2836 |
0.458 |
|
| 2012 |
Attia AS, Schroeder KA, Seeley EH, Wilson KJ, Hammer ND, Colvin DC, Manier ML, Nicklay JJ, Rose KL, Gore JC, Caprioli RM, Skaar EP. Monitoring the inflammatory response to infection through the integration of MALDI IMS and MRI. Cell Host & Microbe. 11: 664-73. PMID 22704626 DOI: 10.1016/J.Chom.2012.04.018 |
0.455 |
|
| 2012 |
Mortensen BL, Skaar EP. Host-microbe interactions that shape the pathogenesis of Acinetobacter baumannii infection. Cellular Microbiology. 14: 1336-44. PMID 22640368 DOI: 10.1111/J.1462-5822.2012.01817.X |
0.538 |
|
| 2012 |
Damo S, Chazin WJ, Skaar EP, Kehl-Fie TE. Inhibition of bacterial superoxide defense: a new front in the struggle between host and pathogen. Virulence. 3: 325-8. PMID 22546907 DOI: 10.4161/Viru.19635 |
0.572 |
|
| 2012 |
Liu JZ, Jellbauer S, Poe AJ, Ton V, Pesciaroli M, Kehl-Fie TE, Restrepo NA, Hosking MP, Edwards RA, Battistoni A, Pasquali P, Lane TE, Chazin WJ, Vogl T, Roth J, ... Skaar EP, et al. Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut. Cell Host & Microbe. 11: 227-39. PMID 22423963 DOI: 10.1016/J.Chom.2012.01.017 |
0.539 |
|
| 2012 |
Pishchany G, Skaar EP. Taste for blood: hemoglobin as a nutrient source for pathogens. Plos Pathogens. 8: e1002535. PMID 22412370 DOI: 10.1371/Journal.Ppat.1002535 |
0.501 |
|
| 2012 |
Wakeman CA, Skaar EP. Metalloregulation of Gram-positive pathogen physiology. Current Opinion in Microbiology. 15: 169-74. PMID 22155062 DOI: 10.1016/J.Mib.2011.11.008 |
0.744 |
|
| 2012 |
Hammer ND, Skaar EP. The impact of metal sequestration on Staphylococcus aureus metabolism. Current Opinion in Microbiology. 15: 10-4. PMID 22153710 DOI: 10.1016/J.Mib.2011.11.004 |
0.528 |
|
| 2012 |
Haley KP, Skaar EP. A battle for iron: host sequestration and Staphylococcus aureus acquisition. Microbes and Infection / Institut Pasteur. 14: 217-27. PMID 22123296 DOI: 10.1016/J.Micinf.2011.11.001 |
0.77 |
|
| 2012 |
Cassat JE, Skaar EP. Metal ion acquisition in Staphylococcus aureus: overcoming nutritional immunity. Seminars in Immunopathology. 34: 215-35. PMID 22048835 DOI: 10.1007/S00281-011-0294-4 |
0.51 |
|
| 2012 |
Damo S, KehlFie T, Holt M, Fritz G, Skaar E, Chazin W. The Molecular Basis for Calprotectin Function in Nutritional Immunity Annals of Paediatric Rheumatology. 1: 3. DOI: 10.5455/Apr.112620120032 |
0.333 |
|
| 2011 |
Krishna Kumar K, Jacques DA, Pishchany G, Caradoc-Davies T, Spirig T, Malmirchegini GR, Langley DB, Dickson CF, Mackay JP, Clubb RT, Skaar EP, Guss JM, Gell DA. Structural basis for hemoglobin capture by Staphylococcus aureus cell-surface protein, IsdH. The Journal of Biological Chemistry. 286: 38439-47. PMID 21917915 DOI: 10.1074/Jbc.M111.287300 |
0.536 |
|
| 2011 |
Anzaldi LL, Skaar EP. The evolution of a superbug: how Staphylococcus aureus overcomes its unique susceptibility to polyamines. Molecular Microbiology. 82: 1-3. PMID 21883524 DOI: 10.1111/J.1365-2958.2011.07808.X |
0.49 |
|
| 2011 |
Kehl-Fie TE, Chitayat S, Hood MI, Damo S, Restrepo N, Garcia C, Munro KA, Chazin WJ, Skaar EP. Nutrient metal sequestration by calprotectin inhibits bacterial superoxide defense, enhancing neutrophil killing of Staphylococcus aureus. Cell Host & Microbe. 10: 158-64. PMID 21843872 DOI: 10.1016/J.Chom.2011.07.004 |
0.57 |
|
| 2011 |
Haley KP, Janson EM, Heilbronner S, Foster TJ, Skaar EP. Staphylococcus lugdunensis IsdG liberates iron from host heme. Journal of Bacteriology. 193: 4749-57. PMID 21764939 DOI: 10.1128/Jb.00436-11 |
0.782 |
|
| 2011 |
Reniere ML, Haley KP, Skaar EP. The flexible loop of Staphylococcus aureus IsdG is required for its degradation in the absence of heme. Biochemistry. 50: 6730-7. PMID 21728357 DOI: 10.1021/Bi200999Q |
0.782 |
|
| 2011 |
Hammer ND, Skaar EP. Molecular mechanisms of Staphylococcus aureus iron acquisition. Annual Review of Microbiology. 65: 129-47. PMID 21639791 DOI: 10.1146/Annurev-Micro-090110-102851 |
0.545 |
|
| 2011 |
Olson PD, Kuechenmeister LJ, Anderson KL, Daily S, Beenken KE, Roux CM, Reniere ML, Lewis TL, Weiss WJ, Pulse M, Nguyen P, Simecka JW, Morrison JM, Sayood K, Asojo OA, ... ... Skaar EP, et al. Small molecule inhibitors of Staphylococcus aureus RnpA alter cellular mRNA turnover, exhibit antimicrobial activity, and attenuate pathogenesis. Plos Pathogens. 7: e1001287. PMID 21347352 DOI: 10.1371/Journal.Ppat.1001287 |
0.473 |
|
| 2011 |
Grossoehme N, Kehl-Fie TE, Ma Z, Adams KW, Cowart DM, Scott RA, Skaar EP, Giedroc DP. Control of copper resistance and inorganic sulfur metabolism by paralogous regulators in Staphylococcus aureus. The Journal of Biological Chemistry. 286: 13522-31. PMID 21339296 DOI: 10.1074/Jbc.M111.220012 |
0.458 |
|
| 2010 |
Pishchany G, McCoy AL, Torres VJ, Krause JC, Crowe JE, Fabry ME, Skaar EP. Specificity for human hemoglobin enhances Staphylococcus aureus infection. Cell Host & Microbe. 8: 544-50. PMID 21147468 DOI: 10.1016/J.Chom.2010.11.002 |
0.71 |
|
| 2010 |
Skaar EP. The battle for iron between bacterial pathogens and their vertebrate hosts. Plos Pathogens. 6: e1000949. PMID 20711357 DOI: 10.1371/Journal.Ppat.1000949 |
0.506 |
|
| 2010 |
Anzaldi LL, Skaar EP. Overcoming the heme paradox: heme toxicity and tolerance in bacterial pathogens. Infection and Immunity. 78: 4977-89. PMID 20679437 DOI: 10.1128/Iai.00613-10 |
0.573 |
|
| 2010 |
Attia AS, Benson MA, Stauff DL, Torres VJ, Skaar EP. Membrane damage elicits an immunomodulatory program in Staphylococcus aureus. Plos Pathogens. 6: e1000802. PMID 20300601 DOI: 10.1371/Journal.Ppat.1000802 |
0.642 |
|
| 2010 |
Jacobs AC, Hood I, Boyd KL, Olson PD, Morrison JM, Carson S, Sayood K, Iwen PC, Skaar EP, Dunman PM. Inactivation of phospholipase D diminishes Acinetobacter baumannii pathogenesis. Infection and Immunity. 78: 1952-62. PMID 20194595 DOI: 10.1128/Iai.00889-09 |
0.796 |
|
| 2010 |
Reniere ML, Ukpabi GN, Harry SR, Stec DF, Krull R, Wright DW, Bachmann BO, Murphy ME, Skaar EP. The IsdG-family of haem oxygenases degrades haem to a novel chromophore. Molecular Microbiology. 75: 1529-38. PMID 20180905 DOI: 10.1111/J.1365-2958.2010.07076.X |
0.381 |
|
| 2010 |
House DL, Chon CH, Creech CB, Skaar EP, Li D. Miniature on-chip detection of unpurified methicillin-resistant Staphylococcus aureus (MRSA) DNA using real-time PCR. Journal of Biotechnology. 146: 93-9. PMID 20149828 DOI: 10.1016/J.Jbiotec.2009.12.013 |
0.39 |
|
| 2010 |
Torres VJ, Attia AS, Mason WJ, Hood MI, Corbin BD, Beasley FC, Anderson KL, Stauff DL, McDonald WH, Zimmerman LJ, Friedman DB, Heinrichs DE, Dunman PM, Skaar EP. Staphylococcus aureus fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia. Infection and Immunity. 78: 1618-28. PMID 20100857 DOI: 10.1128/Iai.01423-09 |
0.702 |
|
| 2010 |
Hood MI, Jacobs AC, Sayood K, Dunman PM, Skaar EP. Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. Antimicrobial Agents and Chemotherapy. 54: 1029-41. PMID 20028819 DOI: 10.1128/Aac.00963-09 |
0.477 |
|
| 2010 |
Kehl-Fie TE, Skaar EP. Nutritional immunity beyond iron: a role for manganese and zinc. Current Opinion in Chemical Biology. 14: 218-24. PMID 20015678 DOI: 10.1016/J.Cbpa.2009.11.008 |
0.561 |
|
| 2010 |
Pishchany G, Skaar EP. Iron Acquisition by Bacillus anthracis Bacillus Anthracis and Anthrax. 106-119. DOI: 10.1002/9780470891193.ch7 |
0.339 |
|
| 2009 |
Mason WJ, Skaar EP. Assessing the contribution of heme-iron acquisition to Staphylococcus aureus pneumonia using computed tomography. Plos One. 4: e6668. PMID 19688098 DOI: 10.1371/Journal.Pone.0006668 |
0.477 |
|
| 2009 |
Stauff DL, Skaar EP. The heme sensor system of Staphylococcus aureus. Contributions to Microbiology. 16: 120-35. PMID 19494582 DOI: 10.1159/000219376 |
0.568 |
|
| 2009 |
Skaar EP. A precious metal heist. Cell Host & Microbe. 5: 422-4. PMID 19454345 DOI: 10.1016/J.Chom.2009.05.005 |
0.544 |
|
| 2009 |
Stauff DL, Skaar EP. Bacillus anthracis HssRS signalling to HrtAB regulates haem resistance during infection. Molecular Microbiology. 72: 763-78. PMID 19400785 DOI: 10.1111/J.1365-2958.2009.06684.X |
0.508 |
|
| 2009 |
Pishchany G, Dickey SE, Skaar EP. Subcellular localization of the Staphylococcus aureus heme iron transport components IsdA and IsdB. Infection and Immunity. 77: 2624-34. PMID 19398548 DOI: 10.1128/Iai.01531-08 |
0.53 |
|
| 2008 |
Lee WC, Reniere ML, Skaar EP, Murphy ME. Ruffling of metalloporphyrins bound to IsdG and IsdI, two heme-degrading enzymes in Staphylococcus aureus. The Journal of Biological Chemistry. 283: 30957-63. PMID 18713745 DOI: 10.1074/Jbc.M709486200 |
0.408 |
|
| 2008 |
Reniere ML, Skaar EP. Staphylococcus aureus haem oxygenases are differentially regulated by iron and haem. Molecular Microbiology. 69: 1304-15. PMID 18643935 DOI: 10.1111/J.1365-2958.2008.06363.X |
0.536 |
|
| 2008 |
Stauff DL, Bagaley D, Torres VJ, Joyce R, Anderson KL, Kuechenmeister L, Dunman PM, Skaar EP. Staphylococcus aureus HrtA is an ATPase required for protection against heme toxicity and prevention of a transcriptional heme stress response. Journal of Bacteriology. 190: 3588-96. PMID 18326576 DOI: 10.1128/Jb.01921-07 |
0.675 |
|
| 2008 |
Corbin BD, Seeley EH, Raab A, Feldmann J, Miller MR, Torres VJ, Anderson KL, Dattilo BM, Dunman PM, Gerads R, Caprioli RM, Nacken W, Chazin WJ, Skaar EP. Metal chelation and inhibition of bacterial growth in tissue abscesses. Science (New York, N.Y.). 319: 962-5. PMID 18276893 DOI: 10.1126/Science.1152449 |
0.676 |
|
| 2008 |
Palazzolo-Ballance AM, Reniere ML, Braughton KR, Sturdevant DE, Otto M, Kreiswirth BN, Skaar EP, DeLeo FR. Neutrophil microbicides induce a pathogen survival response in community-associated methicillin-resistant Staphylococcus aureus. Journal of Immunology (Baltimore, Md. : 1950). 180: 500-9. PMID 18097052 DOI: 10.4049/Jimmunol.180.1.500 |
0.523 |
|
| 2007 |
Torres VJ, Stauff DL, Pishchany G, Bezbradica JS, Gordy LE, Iturregui J, Anderson KL, Dunman PM, Joyce S, Skaar EP. A Staphylococcus aureus regulatory system that responds to host heme and modulates virulence. Cell Host & Microbe. 1: 109-19. PMID 18005689 DOI: 10.1016/J.Chom.2007.03.001 |
0.696 |
|
| 2007 |
Stauff DL, Torres VJ, Skaar EP. Signaling and DNA-binding activities of the Staphylococcus aureus HssR-HssS two-component system required for heme sensing. The Journal of Biological Chemistry. 282: 26111-21. PMID 17635909 DOI: 10.1074/Jbc.M703797200 |
0.686 |
|
| 2007 |
Reniere ML, Torres VJ, Skaar EP. Intracellular metalloporphyrin metabolism in Staphylococcus aureus. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 20: 333-45. PMID 17387580 DOI: 10.1007/S10534-006-9032-0 |
0.702 |
|
| 2006 |
Torres VJ, Pishchany G, Humayun M, Schneewind O, Skaar EP. Staphylococcus aureus IsdB is a hemoglobin receptor required for heme iron utilization. Journal of Bacteriology. 188: 8421-9. PMID 17041042 DOI: 10.1128/Jb.01335-06 |
0.76 |
|
| 2006 |
Friedman DB, Stauff DL, Pishchany G, Whitwell CW, Torres VJ, Skaar EP. Staphylococcus aureus redirects central metabolism to increase iron availability. Plos Pathogens. 2: e87. PMID 16933993 DOI: 10.1371/Journal.Ppat.0020087 |
0.669 |
|
| 2006 |
Skaar EP, Gaspar AH, Schneewind O. Bacillus anthracis IsdG, a heme-degrading monooxygenase. Journal of Bacteriology. 188: 1071-80. PMID 16428411 DOI: 10.1128/Jb.188.3.1071-1080.2006 |
0.661 |
|
| 2005 |
Skaar EP, Lecuyer B, Lenich AG, Lazio MP, Perkins-Balding D, Seifert HS, Karls AC. Analysis of the Piv recombinase-related gene family of Neisseria gonorrhoeae. Journal of Bacteriology. 187: 1276-86. PMID 15687191 DOI: 10.1128/Jb.187.4.1276-1286.2005 |
0.488 |
|
| 2005 |
Wu R, Skaar EP, Zhang R, Joachimiak G, Gornicki P, Schneewind O, Joachimiak A. Staphylococcus aureus IsdG and IsdI, heine-degrading enzymes with structural similarity to monooxygenases Journal of Biological Chemistry. 280: 2840-2846. PMID 15520015 DOI: 10.1074/Jbc.M409526200 |
0.59 |
|
| 2004 |
Skaar EP, Humayun M, Bae T, DeBord KL, Schneewind O. Iron-source preference of Staphylococcus aureus infections. Science (New York, N.Y.). 305: 1626-8. PMID 15361626 DOI: 10.1126/Science.1099930 |
0.739 |
|
| 2004 |
Skaar EP, Schneewind O. Iron-regulated surface determinants (Isd) of Staphylococcus aureus: stealing iron from heme. Microbes and Infection / Institut Pasteur. 6: 390-7. PMID 15101396 DOI: 10.1016/J.Micinf.2003.12.008 |
0.64 |
|
| 2004 |
Skaar EP, Gaspar AH, Schneewind O. IsdG and IsdI, heme-degrading enzymes in the cytoplasm of Staphylococcus aureus. The Journal of Biological Chemistry. 279: 436-43. PMID 14570922 DOI: 10.1074/Jbc.M307952200 |
0.674 |
|
| 2004 |
Kline KA, Sechman EV, Skaar EP, Seifert HS. Erratum: Recombination, repair and replication in the pathogenic Neisseriae: The 3 R's of molecular genetics of two human-specific bacterial pathogens (Molecular Microbiology (6-8)) Molecular Microbiology. 51. DOI: 10.1046/J.1365-2958.2003.03790.X |
0.792 |
|
| 2003 |
Kline KA, Sechman EV, Skaar EP, Seifert HS. Recombination, repair and replication in the pathogenic Neisseriae: the 3 R's of molecular genetics of two human-specific bacterial pathogens. Molecular Microbiology. 50: 3-13. PMID 14507359 DOI: 10.1046/J.1365-2958.2003.03679.X |
0.79 |
|
| 2003 |
Mazmanian SK, Skaar EP, Gaspar AH, Humayun M, Gornicki P, Jelenska J, Joachmiak A, Missiakas DM, Schneewind O. Passage of heme-iron across the envelope of Staphylococcus aureus. Science (New York, N.Y.). 299: 906-9. PMID 12574635 DOI: 10.1126/Science.1081147 |
0.649 |
|
| 2002 |
Skaar EP, Tobiason DM, Quick J, Juddt RC, Weissbach H, Etienne F, Brot N, Seifert HS. The outer membrane localization of the Neisseria gonorrhoeae MsrA/B is involved in survival against reactive oxygen species Proceedings of the National Academy of Sciences of the United States of America. 99: 10108-10113. PMID 12096194 DOI: 10.1073/Pnas.152334799 |
0.55 |
|
| 2002 |
Skaar EP, Seifert HS. The misidentification of bacterial genes as human cDNAs: was the human D-1 tumor antigen gene acquired from bacteria? Genomics. 79: 625-7. PMID 11991711 DOI: 10.1006/Geno.2002.6763 |
0.509 |
|
| 2002 |
Skaar EP, Lazio MP, Seifert HS. Roles of the recJ and recN genes in homologous recombination and DNA repair pathways of Neisseria gonorrhoeae. Journal of Bacteriology. 184: 919-27. PMID 11807051 DOI: 10.1128/Jb.184.4.919-927.2002 |
0.517 |
|
| 2002 |
Hickman JW, Barber RD, Skaar EP, Donohue TJ. Link between the membrane-bound pyridine nucleotide transhydrogenase and glutathione-dependent processes in Rhodobacter sphaeroides. Journal of Bacteriology. 184: 400-9. PMID 11751816 DOI: 10.1128/Jb.184.2.400-409.2002 |
0.428 |
|
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