Eric Y. Denkers - Publications

Affiliations: 
Cornell University, Ithaca, NY, United States 
Area:
Immunology, Pathology, Microbiology Biology

100 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Snyder LM, Belmares-Ortega J, Doherty CM, Denkers EY. Impact of MyD88, Microbiota, and Location on Type 1 and Type 3 Innate Lymphoid Cells during Infection. Immunohorizons. 6: 660-670. PMID 36096673 DOI: 10.4049/immunohorizons.2200070  0.46
2021 Doherty CM, Romero AD, Denkers EY. Impact of IFN-y and CD40 signalling on Toxoplasma gondii cyst formation in differentiated Neuro-2a neuroblastoma cells. Parasite Immunology. 44: e12897. PMID 34762755 DOI: 10.1111/pim.12897  0.375
2021 Snyder LM, Doherty CM, Mercer HL, Denkers EY. Induction of IL-12p40 and type 1 immunity by Toxoplasma gondii in the absence of the TLR-MyD88 signaling cascade. Plos Pathogens. 17: e1009970. PMID 34597344 DOI: 10.1371/journal.ppat.1009970  0.505
2021 Menard KL, Bu L, Denkers EY. Transcriptomics analysis of Toxoplasma gondii-infected mouse macrophages reveals coding and noncoding signatures in the presence and absence of MyD88. Bmc Genomics. 22: 130. PMID 33622246 DOI: 10.1186/s12864-021-07437-0  0.44
2020 Snyder LM, Denkers EY. From Initiators to Effectors: Roadmap Through the Intestine During Encounter of With the Mucosal Immune System. Frontiers in Cellular and Infection Microbiology. 10: 614701. PMID 33505924 DOI: 10.3389/fcimb.2020.614701  0.369
2020 Mercer HL, Snyder LM, Doherty CM, Fox BA, Bzik DJ, Denkers EY. Toxoplasma gondii dense granule protein GRA24 drives MyD88-independent p38 MAPK activation, IL-12 production and induction of protective immunity. Plos Pathogens. 16: e1008572. PMID 32413093 DOI: 10.1371/journal.ppat.1008572  0.454
2018 Menard KL, Haskins BE, Colombo AP, Denkers EY. Toxoplasma gondii Manipulates Expression of Host Long Noncoding RNA during Intracellular Infection. Scientific Reports. 8: 15017. PMID 30301916 DOI: 10.1038/s41598-018-33274-5  0.34
2015 Sun S, Lourie R, Cohen SB, Ji Y, Goodrich JK, Poole AC, Ley RE, Denkers EY, McGuckin MA, Long Q, Duhamel GE, Simpson KW, Qi L. Epithelial Sel1L is required for the maintenance of intestinal homeostasis. Molecular Biology of the Cell. PMID 26631554 DOI: 10.1091/Mbc.E15-10-0724  0.345
2015 Cohen SB, Denkers EY. Impact of Toxoplasma gondii on Dendritic Cell Subset Function in the Intestinal Mucosa. Journal of Immunology (Baltimore, Md. : 1950). 195: 2754-62. PMID 26283477 DOI: 10.4049/Jimmunol.1501137  0.479
2015 Cohen SB, Denkers EY. The gut mucosal immune response to Toxoplasma gondii Parasite Immunology. 37: 108-117. PMID 25418610 DOI: 10.1111/pim.12164  0.356
2015 Cohen SB, Smith NL, McDougal C, Pepper M, Shah S, Yap GS, Acha-Orbea H, Jiang A, Clausen BE, Rudd BD, Denkers EY. Beta-catenin signaling drives differentiation and proinflammatory function of IRF8-dependent dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 194: 210-22. PMID 25416805 DOI: 10.4049/Jimmunol.1402453  0.377
2014 Cohen SB, Denkers EY. Border maneuvers: Deployment of mucosal immune defenses against Toxoplasma gondii Mucosal Immunology. 7: 744-752. PMID 24717355 DOI: 10.1038/Mi.2014.25  0.435
2013 Cohen SB, Maurer KJ, Egan CE, Oghumu S, Satoskar AR, Denkers EY. CXCR3-Dependent CD4+ T Cells Are Required to Activate Inflammatory Monocytes for Defense against Intestinal Infection Plos Pathogens. 9. PMID 24130498 DOI: 10.1371/Journal.Ppat.1003706  0.565
2013 Smith NL, Abi Abdallah DS, Butcher BA, Denkers EY, Baird B, Holowka D. Toxoplasma gondii inhibits mast cell degranulation by suppressing phospholipase Cγ-mediated Ca(2+) mobilization. Frontiers in Microbiology. 4: 179. PMID 23847603 DOI: 10.3389/Fmicb.2013.00179  0.822
2013 Egan CE, Daugherity EK, Rogers AB, Abi Abdallah DS, Denkers EY, Maurer KJ. CCR2 and CD44 Promote Inflammatory Cell Recruitment during Fatty Liver Formation in a Lithogenic Diet Fed Mouse Model Plos One. 8. PMID 23762326 DOI: 10.1371/Journal.Pone.0065247  0.779
2013 Schneider AG, Abi Abdallah DS, Butcher BA, Denkers EY. Toxoplasma gondii triggers phosphorylation and nuclear translocation of dendritic cell STAT1 while simultaneously blocking IFNγ-induced STAT1 transcriptional activity. Plos One. 8: e60215. PMID 23527309 DOI: 10.1371/Journal.Pone.0060215  0.842
2012 Abi Abdallah DS, Denkers EY. Neutrophils cast extracellular traps in response to protozoan parasites. Frontiers in Immunology. 3: 382. PMID 23248631 DOI: 10.3389/Fimmu.2012.00382  0.813
2012 Mahamed DA, Mills JH, Egan CE, Denkers EY, Bynoe MS. CD73-generated adenosine facilitates Toxoplasma gondii differentiation to long-lived tissue cysts in the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 109: 16312-7. PMID 22988118 DOI: 10.1073/Pnas.1205589109  0.432
2012 McBerry C, Egan CE, Rani R, Yang Y, Wu D, Boespflug N, Boon L, Butcher B, Mirpuri J, Hogan SP, Denkers EY, Aliberti J, Herbert DR. Trefoil factor 2 negatively regulates type 1 immunity against Toxoplasma gondii. Journal of Immunology (Baltimore, Md. : 1950). 189: 3078-84. PMID 22896633 DOI: 10.4049/Jimmunol.1103374  0.584
2012 Denkers EY, Schneider AG, Cohen SB, Butcher BA. Phagocyte responses to protozoan infection and how Toxoplasma gondii meets the challenge. Plos Pathogens. 8: e1002794. PMID 22876173 DOI: 10.1371/Journal.Ppat.1002794  0.596
2012 Craven M, Egan CE, Dowd SE, McDonough SP, Dogan B, Denkers EY, Bowman D, Scherl EJ, Simpson KW. Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's disease. Plos One. 7: e41594. PMID 22848538 DOI: 10.1371/Journal.Pone.0041594  0.32
2012 Abi Abdallah DS, Lin C, Ball CJ, King MR, Duhamel GE, Denkers EY. Toxoplasma gondii triggers release of human and mouse neutrophil extracellular traps. Infection and Immunity. 80: 768-77. PMID 22104111 DOI: 10.1128/Iai.05730-11  0.834
2012 Denkers EY, Bzik DJ, Fox BA, Butcher BA. An inside job: hacking into Janus kinase/signal transducer and activator of transcription signaling cascades by the intracellular protozoan Toxoplasma gondii. Infection and Immunity. 80: 476-82. PMID 22104110 DOI: 10.1128/Iai.05974-11  0.475
2012 Egan CE, Cohen SB, Denkers EY. Insights into inflammatory bowel disease using Toxoplasma gondii as an infectious trigger. Immunology and Cell Biology. 90: 668-75. PMID 22064707 DOI: 10.1038/Icb.2011.93  0.494
2012 Denkers EY, Butcher BA. Toxoplasma gondii parasites take control within host cells: This parasite puppet master lives mostly without causing disease for its hosts, establishing lifelong asymptomatic infections Microbe. 7. DOI: 10.1128/Microbe.7.360.1  0.479
2011 Butcher BA, Fox BA, Rommereim LM, Kim SG, Maurer KJ, Yarovinsky F, Herbert DR, Bzik DJ, Denkers EY. Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control. Plos Pathogens. 7: e1002236. PMID 21931552 DOI: 10.1371/Journal.Ppat.1002236  0.616
2011 Egan CE, Maurer KJ, Cohen SB, Mack M, Simpson KW, Denkers EY. Synergy between intraepithelial lymphocytes and lamina propria T cells drives intestinal inflammation during infection. Mucosal Immunology. 4: 658-70. PMID 21796113 DOI: 10.1038/Mi.2011.31  0.49
2011 Abi Abdallah DS, Egan CE, Butcher BA, Denkers EY. Mouse neutrophils are professional antigen-presenting cells programmed to instruct Th1 and Th17 T-cell differentiation. International Immunology. 23: 317-26. PMID 21422151 DOI: 10.1093/Intimm/Dxr007  0.806
2011 Denkers EY. Understanding neutrophil function during Toxoplasma gondii infection Neutrophils in Infectious Diseases. 59-66. DOI: 10.2174/978160805023911101010059  0.408
2010 Sukhumavasi W, Warren AL, Del Rio L, Denkers EY. Absence of mitogen-activated protein kinase family member c-Jun N-terminal kinase-2 enhances resistance to Toxoplasma gondii. Experimental Parasitology. 126: 415-20. PMID 20117109 DOI: 10.1016/J.Exppara.2010.01.019  0.802
2010 Denkers EY. Toll-like receptor initiated host defense against Toxoplasma gondii. Journal of Biomedicine & Biotechnology. 2010: 737125. PMID 19911079 DOI: 10.1155/2010/737125  0.447
2010 Craven M, Egan CE, Dogan B, Dowd SE, Denkers E, McDonough S, Scherl EJ, Simpson KW. 68 CCR2 Deletion Ameloriates Ileal Inflammation, Limits Dysbiosis, and Prevents Invasion by Adherent and Invasive E. coli (AIEC) in Toxoplasma gondii Infected Mice Gastroenterology. 138: S-14. DOI: 10.1016/S0016-5085(10)60063-7  0.392
2009 Leng J, Butcher BA, Denkers EY. Dysregulation of macrophage signal transduction by Toxoplasma gondii: past progress and recent advances. Parasite Immunology. 31: 717-28. PMID 19891610 DOI: 10.1111/J.1365-3024.2009.01122.X  0.733
2009 Leng J, Denkers EY. Toxoplasma gondii inhibits covalent modification of histone H3 at the IL-10 promoter in infected macrophages. Plos One. 4: e7589. PMID 19859561 DOI: 10.1371/Journal.Pone.0007589  0.742
2009 Egan CE, Craven MD, Leng J, Mack M, Simpson KW, Denkers EY. CCR2-dependent intraepithelial lymphocytes mediate inflammatory gut pathology during Toxoplasma gondii infection. Mucosal Immunology. 2: 527-35. PMID 19741601 DOI: 10.1038/Mi.2009.105  0.755
2009 Denkers EY. A gut feeling for microbes: getting it going between a parasite and its host. Cell Host & Microbe. 6: 104-6. PMID 19683676 DOI: 10.1016/J.Chom.2009.07.009  0.364
2009 Egan CE, Sukhumavasi W, Butcher BA, Denkers EY. Functional aspects of Toll-like receptor/MyD88 signalling during protozoan infection: focus on Toxoplasma gondii. Clinical and Experimental Immunology. 156: 17-24. PMID 19161444 DOI: 10.1111/J.1365-2249.2009.03876.X  0.81
2009 Leng J, Butcher BA, Egan CE, Abi Abdallah DS, Denkers EY. Toxoplasma gondii prevents chromatin remodeling initiated by TLR-triggered macrophage activation. Journal of Immunology (Baltimore, Md. : 1950). 182: 489-97. PMID 19109180 DOI: 10.4049/Jimmunol.182.1.489  0.813
2008 Bierly AL, Shufesky WJ, Sukhumavasi W, Morelli AE, Denkers EY. Dendritic cells expressing plasmacytoid marker PDCA-1 are Trojan horses during Toxoplasma gondii infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 8485-91. PMID 19050266 DOI: 10.4049/Jimmunol.181.12.8485  0.817
2008 Sukhumavasi W, Egan CE, Warren AL, Taylor GA, Fox BA, Bzik DJ, Denkers EY. TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite. Journal of Immunology (Baltimore, Md. : 1950). 181: 3464-73. PMID 18714019 DOI: 10.4049/Jimmunol.181.5.3464  0.841
2008 Denkers EY, Striepen B. Deploying parasite profilin on a mission of invasion and danger. Cell Host & Microbe. 3: 61-3. PMID 18312839 DOI: 10.1016/J.Chom.2008.01.003  0.525
2008 Egan CE, Sukhumavasi W, Bierly AL, Denkers EY. Understanding the multiple functions of Gr-1(+) cell subpopulations during microbial infection. Immunologic Research. 40: 35-48. PMID 18193362 DOI: 10.1007/S12026-007-0061-8  0.798
2008 Egan CE, Sukhumavasi W, Butcher BA, Denkers EY. Functional Aspects of TLR-MyD88 Signaling During Protozoan Infection: Focus onToxoplasma gondii Clinical and Experimental Immunology. DOI: 10.1111/J.1365-2249.2008.03876.X  0.798
2007 Lee CW, Sukhumavasi W, Denkers EY. Phosphoinositide-3-kinase-dependent, MyD88-independent induction of CC-type chemokines characterizes the macrophage response to Toxoplasma gondii strains with high virulence Infection and Immunity. 75: 5788-5797. PMID 17908814 DOI: 10.1128/Iai.00821-07  0.802
2007 Sukhumavasi W, Egan CE, Denkers EY. Mouse neutrophils require JNK2 MAPK for Toxoplasma gondii-induced IL-12p40 and CCL2/MCP-1 release. Journal of Immunology (Baltimore, Md. : 1950). 179: 3570-7. PMID 17785791 DOI: 10.4049/Jimmunol.179.6.3570  0.817
2006 Gazzinelli RT, Denkers EY. Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism. Nature Reviews. Immunology. 6: 895-906. PMID 17110955 DOI: 10.1038/Nri1978  0.471
2006 Kim L, Butcher BA, Lee CW, Uematsu S, Akira S, Denkers EY. Toxoplasma gondii genotype determines MyD88-dependent signaling in infected macrophages Journal of Immunology. 177: 2584-2591. PMID 16888020 DOI: 10.4049/Jimmunol.177.4.2584  0.804
2006 Bennouna S, Sukhumavasi W, Denkers EY. Toxoplasma gondii inhibits toll-like receptor 4 ligand-induced mobilization of intracellular tumor necrosis factor alpha to the surface of mouse peritoneal neutrophils. Infection and Immunity. 74: 4274-81. PMID 16790802 DOI: 10.1128/Iai.01573-05  0.806
2006 Kim L, Denkers EY. Toxoplasma gondii triggers Gi-dependent PI 3-kinase signaling required for inhibition of host cell apoptosis. Journal of Cell Science. 119: 2119-26. PMID 16638808 DOI: 10.1242/Jcs.02934  0.774
2006 Lee CW, Bennouna S, Denkers EY. Screening for Toxoplasma gondii-regulated transcriptional responses in lipopolysaccharide-activated macrophages Infection and Immunity. 74: 1916-1923. PMID 16495567 DOI: 10.1128/Iai.74.3.1916-1923.2006  0.853
2005 Butcher BA, Greene RI, Henry SC, Annecharico KL, Weinberg JB, Denkers EY, Sher A, Taylor GA. p47 GTPases regulate Toxoplasma gondii survival in activated macrophages. Infection and Immunity. 73: 3278-86. PMID 15908352 DOI: 10.1128/Iai.73.6.3278-3286.2005  0.493
2005 Bennouna S, Denkers EY. Microbial antigen triggers rapid mobilization of TNF-alpha to the surface of mouse neutrophils transforming them into inducers of high-level dendritic cell TNF-alpha production. Journal of Immunology (Baltimore, Md. : 1950). 174: 4845-51. PMID 15814711 DOI: 10.4049/Jimmunol.174.8.4845  0.824
2005 Kim L, Del Rio L, Butcher BA, Mogensen TH, Paludan SR, Flavell RA, Denkers EY. p38 MAPK autophosphorylation drives macrophage IL-12 production during intracellular infection. Journal of Immunology (Baltimore, Md. : 1950). 174: 4178-84. PMID 15778378 DOI: 10.4049/Jimmunol.174.7.4178  0.771
2005 Butcher BA, Kim L, Panopoulos AD, Watowich SS, Murray PJ, Denkers EY. IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-alpha in host macrophages. Journal of Immunology (Baltimore, Md. : 1950). 174: 3148-52. PMID 15749841 DOI: 10.4049/Jimmunol.174.6.3148  0.809
2005 Denkers EY, Butcher BA. Sabotage and exploitation in macrophages parasitized by intracellular protozoans. Trends in Parasitology. 21: 35-41. PMID 15639739 DOI: 10.1016/J.Pt.2004.10.004  0.521
2005 Kim L, Butcher B, Denkers E. Playing with Fire: Manipulation of Macrophage Proinflammatory Signal Transduction by the Intracellular Protozoan Toxoplasma gondii Current Immunology Reviews. 1: 213-222. DOI: 10.2174/157339505774479220  0.746
2004 Denkers EY, Butcher BA, Del Rio L, Kim L. Manipulation of mitogen-activated protein kinase/nuclear factor-kappaB-signaling cascades during intracellular Toxoplasma gondii infection. Immunological Reviews. 201: 191-205. PMID 15361242 DOI: 10.1111/J.0105-2896.2004.00180.X  0.808
2004 Del Rio L, Butcher BA, Bennouna S, Hieny S, Sher A, Denkers EY. Toxoplasma gondii triggers myeloid differentiation factor 88-dependent IL-12 and chemokine ligand 2 (monocyte chemoattractant protein 1) responses using distinct parasite molecules and host receptors. Journal of Immunology (Baltimore, Md. : 1950). 172: 6954-60. PMID 15153515 DOI: 10.4049/Jimmunol.172.11.6954  0.832
2004 Denkers EY, Butcher BA, Del Rio L, Bennouna S. Neutrophils, dendritic cells and Toxoplasma. International Journal For Parasitology. 34: 411-21. PMID 15003500 DOI: 10.1016/J.Ijpara.2003.11.001  0.859
2004 Kim L, Butcher BA, Denkers EY. Toxoplasma gondii interferes with lipopolysaccharide-induced mitogen-activated protein kinase activation by mechanisms distinct from endotoxin tolerance. Journal of Immunology (Baltimore, Md. : 1950). 172: 3003-10. PMID 14978104 DOI: 10.4049/Jimmunol.172.5.3003  0.778
2004 Gavrilescu LC, Butcher BA, Del Rio L, Taylor GA, Denkers EY. STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection. Infection and Immunity. 72: 1257-64. PMID 14977926 DOI: 10.1128/Iai.72.3.1257-1264.2004  0.834
2003 Denkers EY. From cells to signaling cascades: manipulation of innate immunity by Toxoplasma gondii. Fems Immunology and Medical Microbiology. 39: 193-203. PMID 14642303 DOI: 10.1016/S0928-8244(03)00279-7  0.631
2003 Bennouna S, Bliss SK, Curiel TJ, Denkers EY. Cross-talk in the innate immune system: neutrophils instruct recruitment and activation of dendritic cells during microbial infection. Journal of Immunology (Baltimore, Md. : 1950). 171: 6052-8. PMID 14634118 DOI: 10.4049/Jimmunol.171.11.6052  0.847
2003 Gavrilescu LC, Denkers EY. Apoptosis and the balance of homeostatic and pathologic responses to protozoan infection. Infection and Immunity. 71: 6109-15. PMID 14573625 DOI: 10.1128/Iai.71.11.6109-6115.2003  0.775
2003 Denkers EY, Del Rio L, Bennouna S. Neutrophil production of IL-12 and other cytokines during microbial infection. Chemical Immunology and Allergy. 83: 95-114. PMID 12947981 DOI: 10.1159/000071557  0.831
2003 Gavrilescu LC, Denkers EY. Interleukin-12 p40- and Fas ligand-dependent apoptotic pathways involving STAT-1 phosphorylation are triggered during infection with a virulent strain of Toxoplasma gondii. Infection and Immunity. 71: 2577-83. PMID 12704131 DOI: 10.1128/Iai.71.5.2577-2583.2003  0.836
2003 Denkers EY, Kim L, Butcher BA. In the belly of the beast: subversion of macrophage proinflammatory signalling cascades during Toxoplasma gondii infection. Cellular Microbiology. 5: 75-83. PMID 12580944 DOI: 10.1046/J.1462-5822.2003.00258.X  0.838
2003 Straw AD, MacDonald AS, Denkers EY, Pearce EJ. CD154 plays a central role in regulating dendritic cell activation during infections that induce Th1 or Th2 responses. Journal of Immunology (Baltimore, Md. : 1950). 170: 727-34. PMID 12517934 DOI: 10.4049/Jimmunol.170.2.727  0.811
2002 Butcher BA, Denkers EY. Mechanism of entry determines the ability of Toxoplasma gondii to inhibit macrophage proinflammatory cytokine production. Infection and Immunity. 70: 5216-24. PMID 12183573 DOI: 10.1128/Iai.70.9.5216-5224.2002  0.548
2002 Scanga CA, Aliberti J, Jankovic D, Tilloy F, Bennouna S, Denkers EY, Medzhitov R, Sher A. Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 5997-6001. PMID 12055206 DOI: 10.4049/Jimmunol.168.12.5997  0.843
2001 Del Rio L, Bennouna S, Salinas J, Denkers EY. CXCR2 deficiency confers impaired neutrophil recruitment and increased susceptibility during Toxoplasma gondii infection. Journal of Immunology (Baltimore, Md. : 1950). 167: 6503-9. PMID 11714818 DOI: 10.4049/Jimmunol.167.11.6503  0.847
2001 Butcher BA, Kim L, Johnson PF, Denkers EY. Toxoplasma gondii tachyzoites inhibit proinflammatory cytokine induction in infected macrophages by preventing nuclear translocation of the transcription factor NF-kappa B. Journal of Immunology (Baltimore, Md. : 1950). 167: 2193-201. PMID 11490005 DOI: 10.4049/Jimmunol.167.4.2193  0.806
2001 Bliss SK, Gavrilescu LC, Alcaraz A, Denkers EY. Neutrophil depletion during Toxoplasma gondii infection leads to impaired immunity and lethal systemic pathology. Infection and Immunity. 69: 4898-905. PMID 11447166 DOI: 10.1128/Iai.69.8.4898-4905.2001  0.852
2001 Gavrilescu LC, Denkers EY. IFN-gamma overproduction and high level apoptosis are associated with high but not low virulence Toxoplasma gondii infection. Journal of Immunology (Baltimore, Md. : 1950). 167: 902-9. PMID 11441097 DOI: 10.4049/Jimmunol.167.2.902  0.825
2001 Araujo MI, Bliss SK, Suzuki Y, Alcaraz A, Denkers EY, Pearce EJ. Interleukin-12 promotes pathologic liver changes and death in mice coinfected with Schistosoma mansoni and Toxoplasma gondii. Infection and Immunity. 69: 1454-62. PMID 11179312 DOI: 10.1128/Iai.69.3.1454-1462.2001  0.814
2000 Bliss SK, Butcher BA, Denkers EY. Rapid recruitment of neutrophils containing prestored IL-12 during microbial infection. Journal of Immunology (Baltimore, Md. : 1950). 165: 4515-21. PMID 11035091 DOI: 10.4049/Jimmunol.165.8.4515  0.809
1999 Denkers EY. T lymphocyte-dependent effector mechanisms of immunity to Toxoplasma gondii Microbes and Infection. 1: 699-708. PMID 10611747 DOI: 10.1016/S1286-4579(99)80071-9  0.55
1999 Zhang Y, Denkers EY. Protective role for interleukin-5 during chronic Toxoplasma gondii infection Infection and Immunity. 67: 4383-4392. PMID 10456878 DOI: 10.1128/Iai.67.9.4383-4392.1999  0.515
1999 Marshall AJ, Brunet LR, van Gessel Y, Alcaraz A, Bliss SK, Pearce EJ, Denkers EY. Toxoplasma gondii and Schistosoma mansoni synergize to promote hepatocyte dysfunction associated with high levels of plasma TNF-alpha and early death in C57BL/6 mice. Journal of Immunology (Baltimore, Md. : 1950). 163: 2089-97. PMID 10438948  0.791
1999 Bliss SK, Zhang Y, Denkers EY. Murine neutrophil stimulation by Toxoplasma gondii antigen drives high level production of IFN-gamma-independent IL-12. Journal of Immunology (Baltimore, Md. : 1950). 163: 2081-8. PMID 10438947  0.815
1999 Bliss SK, Marshall AJ, Zhang Y, Denkers EY. Human polymorphonuclear leukocytes produce IL-12, TNF-alpha, and the chemokines macrophage-inflammatory protein-1 alpha and -1 beta in response to Toxoplasma gondii antigens. Journal of Immunology (Baltimore, Md. : 1950). 162: 7369-75. PMID 10358188  0.784
1999 Zhang Y, Denkers EY. Protective Role for Interleukin-5 during Chronic Toxoplasma gondii Infection Infection and Immunity. 67: 4383-4392. DOI: 10.1128/iai.67.9.4383-4392.1999  0.419
1998 Denkers EY, Gazzinelli RT. Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection Clinical Microbiology Reviews. 11: 569-588. PMID 9767056 DOI: 10.1128/Cmr.11.4.569  0.565
1998 Marshall AJ, Denkers EY. Toxoplasma gondii triggers granulocyte-dependent cytokine-mediated lethal shock in D-galactosamine-sensitized mice. Infection and Immunity. 66: 1325-33. PMID 9529049 DOI: 10.1128/Iai.66.4.1325-1333.1998  0.433
1998 Denkers EY, Marshall AJ. Neutrophils as a source of immunoregulatory cytokines during microbial infection Immunologist. 6: 116-120.  0.459
1997 Denkers EY, Yap G, Scharton-Kersten T, Charest H, Butcher BA, Caspar P, Heiny S, Sher A. Perforin-Mediated Cytolysis Plays a Limited Role in Host Resistance to Toxoplasma gondii Journal of Immunology. 159: 1903-1908. PMID 9257855  0.355
1997 Denkers EY, Sher A. Role of natural killer and NK1+ T-cells in regulating cell-mediated immunity during Toxoplasma gondii infection Biochemical Society Transactions. 25: 699-703. PMID 9191186 DOI: 10.1042/Bst0250699  0.504
1996 Denkers EY. A Toxoplasma gondii superantigen: Biological effects and implications for the host-parasite interaction Parasitology Today. 12: 362-366. PMID 15275175 DOI: 10.1016/0169-4758(96)10028-4  0.481
1996 Scharton-Kersten T, Caspar P, Sher A, Denkers EY. Toxoplasma gondii: Evidence for interleukin-12-dependent and -independent pathways of interferon-γ production induced by an attenuated parasite strain Experimental Parasitology. 84: 102-114. PMID 8932760 DOI: 10.1006/Expr.1996.0096  0.547
1996 Scharton-Kersten TM, Wynn TA, Denkers EY, Bala S, Grunvald E, Hieny S, Gazzinelli RT, Sher A. In the Absence of Endogenous IFN-γ, Mice Develop Unimpaired IL-12 Responses to Toxoplasma gondii while Failing to Control Acute Infection Journal of Immunology. 157: 4045-4054. PMID 8892638  0.43
1996 Denkers EY, Scharton-Kersten T, Barbieri S, Caspar P, Sher A. A role for CD4+NK1.1+ T lymphocytes as major histocompatibility complex class II independent helper cells in the generation of CD8+ effector function against intracellular infection Journal of Experimental Medicine. 184: 131-139. PMID 8691126 DOI: 10.1084/Jem.184.1.131  0.485
1996 Denkers EY, Caspar P, Hieny S, Sher A. Toxoplasma gondii infection induces specific nonresponsiveness in lymphocytes bearing the Vβ5 chain of the mouse T cell receptor Journal of Immunology. 156: 1089-1094. PMID 8557983  0.426
1996 Denkers EY, Yap G, Charest H, Scharton-Karsten T, Butcher BA, Sher A. Perforin knockout mice retain cd8+ t lymphocyte immunity to toxoplasma gondii despite absence of parasite-specific ctl function Faseb Journal. 10.  0.416
1995 Scharton-Kersten T, Denkers EY, Gazzinelli R, Sher A. Role of IL 12 in induction of cell-mediated immunity to Toxoplasma gondii Research in Immunology. 146: 539-545. PMID 8839159 DOI: 10.1016/0923-2494(96)83029-X  0.474
1995 Sher A, Denkers EY, Gazzinelli RT. Induction and regulation of host cell-mediated immunity by Toxoplasma gondii Ciba Foundation Symposium. 195. PMID 8724832  0.481
1994 Denkers EY, Caspar P, Sher A. Toxoplasma gondii possesses a superantigen activity that selectively expands murine T cell receptor Vβ5-bearing CD8+ lymphocytes Journal of Experimental Medicine. 180: 985-994. PMID 8064244 DOI: 10.1084/Jem.180.3.985  0.498
1994 Gazzinelli RT, Wysocka M, Hayashi S, Denkers EY, Hieny S, Caspar P, Trinchieri G, Sher A. Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii Journal of Immunology. 153: 2533-2543. PMID 7915739  0.443
1993 Denkers EY, Gazzinelli RT, Martin D, Sher A. Emergence of NK1.1+ cells as effectors of IFN-γ dependent immunity to Toxoplasma gondii in MHC class I-deficient mice Journal of Experimental Medicine. 178: 1465-1472. PMID 8228800 DOI: 10.1084/Jem.178.5.1465  0.461
1993 Denkers EY, Sher A, Gazzinelli RT. CD8+ T-cell interactions with Toxoplasma gondii: implications for processing of antigen for class-I-restricted recognition Research in Immunology. 144: 51-57. PMID 8095730 DOI: 10.1016/S0923-2494(05)80099-9  0.428
1993 Gazzinelli RT, Denkers EY, Sher A. Host resistance to Toxoplasma gondii: Model for studying the selective induction of cell-mediated immunity by intracellular parasites Infectious Agents and Disease. 2: 139-149. PMID 7909708  0.331
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