Brian N. Finck, Ph.D. - Publications

Affiliations: 
2000 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Animal Physiology Biology, Cell Biology, Molecular Biology

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Wang J, Kim C, Jogasuria A, Han Y, Hu X, Wu J, Shen H, Chrast R, Finck BN, You M. Myeloid Cell-Specific Lipin-1 Deficiency Stimulates Endocrine Adiponectin-FGF15 Axis and Ameliorates Ethanol-Induced Liver Injury in Mice. Scientific Reports. 6: 34117. PMID 27666676 DOI: 10.1038/srep34117  0.4
2016 DeBosch BJ, Heitmeier MR, Mayer AL, Higgins CB, Crowley JR, Kraft TE, Chi M, Newberry EP, Chen Z, Finck BN, Davidson NO, Yarasheski KE, Hruz PW, Moley KH. Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis. Science Signaling. 9: ra21. PMID 26905426 DOI: 10.1126/scisignal.aac5472  0.4
2015 McCommis KS, Chen Z, Fu X, McDonald WG, Colca JR, Kletzien RF, Burgess SC, Finck BN. Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling. Cell Metabolism. 22: 682-94. PMID 26344101 DOI: 10.1016/j.cmet.2015.07.028  0.4
2015 Finck BN, Hall AM. Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance? Biomed Research International. 2015: 104132. PMID 26273583 DOI: 10.1155/2015/104132  0.4
2015 Schweitzer GG, Chen Z, Gan C, McCommis KS, Soufi N, Chrast R, Mitra MS, Yang K, Gross RW, Finck BN. Liver-specific loss of lipin-1-mediated phosphatidic acid phosphatase activity does not mitigate intrahepatic TG accumulation in mice. Journal of Lipid Research. 56: 848-58. PMID 25722343 DOI: 10.1194/jlr.M055962  0.4
2014 Mazar J, Zhao W, Khalil AM, Lee B, Shelley J, Govindarajan SS, Yamamoto F, Ratnam M, Aftab MN, Collins S, Finck BN, Han X, Mattick JS, Dinger ME, Perera RJ. The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells. Oncotarget. 5: 8959-69. PMID 25344859  0.4
2014 Soufi N, Hall AM, Chen Z, Yoshino J, Collier SL, Mathews JC, Brunt EM, Albert CJ, Graham MJ, Ford DA, Finck BN. Inhibiting monoacylglycerol acyltransferase 1 ameliorates hepatic metabolic abnormalities but not inflammation and injury in mice. The Journal of Biological Chemistry. 289: 30177-88. PMID 25213859 DOI: 10.1074/jbc.M114.595850  0.4
2014 Devanathan S, Whitehead T, Schweitzer GG, Fettig N, Kovacs A, Korach KS, Finck BN, Shoghi KI. An animal model with a cardiomyocyte-specific deletion of estrogen receptor alpha: functional, metabolic, and differential network analysis. Plos One. 9: e101900. PMID 25000186 DOI: 10.1371/journal.pone.0101900  0.4
2014 Vigueira PA, McCommis KS, Schweitzer GG, Remedi MS, Chambers KT, Fu X, McDonald WG, Cole SL, Colca JR, Kletzien RF, Burgess SC, Finck BN. Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion. Cell Reports. 7: 2042-53. PMID 24910426 DOI: 10.1016/j.celrep.2014.05.017  0.4
2014 Eaton JM, Takkellapati S, Lawrence RT, McQueeney KE, Boroda S, Mullins GR, Sherwood SG, Finck BN, Villén J, Harris TE. Lipin 2 binds phosphatidic acid by the electrostatic hydrogen bond switch mechanism independent of phosphorylation. The Journal of Biological Chemistry. 289: 18055-66. PMID 24811178 DOI: 10.1074/jbc.M114.547604  0.4
2014 Hall AM, Soufi N, Chambers KT, Chen Z, Schweitzer GG, McCommis KS, Erion DM, Graham MJ, Su X, Finck BN. Abrogating monoacylglycerol acyltransferase activity in liver improves glucose tolerance and hepatic insulin signaling in obese mice. Diabetes. 63: 2284-96. PMID 24595352 DOI: 10.2337/db13-1502  0.4
2014 Debosch BJ, Chen Z, Saben JL, Finck BN, Moley KH. Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis. The Journal of Biological Chemistry. 289: 10989-98. PMID 24519932 DOI: 10.1074/jbc.M113.527002  0.4
2013 Chambers KT, Chen Z, Lai L, Leone TC, Towle HC, Kralli A, Crawford PA, Finck BN. PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner. Molecular Metabolism. 2: 194-204. PMID 24049734 DOI: 10.1016/j.molmet.2013.05.001  0.4
2013 DeBosch BJ, Chen Z, Finck BN, Chi M, Moley KH. Glucose transporter-8 (GLUT8) mediates glucose intolerance and dyslipidemia in high-fructose diet-fed male mice. Molecular Endocrinology (Baltimore, Md.). 27: 1887-96. PMID 24030250 DOI: 10.1210/me.2013-1137  0.4
2013 Hu M, Yin H, Mitra MS, Liang X, Ajmo JM, Nadra K, Chrast R, Finck BN, You M. Hepatic-specific lipin-1 deficiency exacerbates experimental alcohol-induced steatohepatitis in mice. Hepatology (Baltimore, Md.). 58: 1953-63. PMID 23787969 DOI: 10.1002/hep.26589  0.4
2013 Colca JR, McDonald WG, Cavey GS, Cole SL, Holewa DD, Brightwell-Conrad AS, Wolfe CL, Wheeler JS, Coulter KR, Kilkuskie PM, Gracheva E, Korshunova Y, Trusgnich M, Karr R, Wiley SE, ... ... Finck BN, et al. Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins. Plos One. 8: e61551. PMID 23690925 DOI: 10.1371/journal.pone.0061551  0.4
2013 Fabbrini E, Cella M, McCartney SA, Fuchs A, Abumrad NA, Pietka TA, Chen Z, Finck BN, Han DH, Magkos F, Conte C, Bradley D, Fraterrigo G, Eagon JC, Patterson BW, et al. Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals. Gastroenterology. 145: 366-74.e1-3. PMID 23597726 DOI: 10.1053/j.gastro.2013.04.010  0.4
2013 Mitra MS, Chen Z, Ren H, Harris TE, Chambers KT, Hall AM, Nadra K, Klein S, Chrast R, Su X, Morris AJ, Finck BN. Mice with an adipocyte-specific lipin 1 separation-of-function allele reveal unexpected roles for phosphatidic acid in metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America. 110: 642-7. PMID 23267081 DOI: 10.1073/pnas.1213493110  0.4
2012 Chambers KT, Chen Z, Crawford PA, Fu X, Burgess SC, Lai L, Leone TC, Kelly DP, Finck BN. Liver-specific PGC-1beta deficiency leads to impaired mitochondrial function and lipogenic response to fasting-refeeding. Plos One. 7: e52645. PMID 23285128 DOI: 10.1371/journal.pone.0052645  0.4
2012 Wang S, Chen Z, Lam V, Han J, Hassler J, Finck BN, Davidson NO, Kaufman RJ. IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis. Cell Metabolism. 16: 473-86. PMID 23040069 DOI: 10.1016/j.cmet.2012.09.003  0.4
2012 Solingapuram Sai KK, Kil KE, Tu Z, Chu W, Finck BN, Rothfuss JM, Shoghi KI, Welch MJ, Gropler RJ, Mach RH. Synthesis, radiolabeling and initial in vivo evaluation of [(11)C]KSM-01 for imaging PPAR-α receptors. Bioorganic & Medicinal Chemistry Letters. 22: 6233-6. PMID 22939697 DOI: 10.1016/j.bmcl.2012.08.010  0.4
2012 Chen Z, Vigueira PA, Chambers KT, Hall AM, Mitra MS, Qi N, McDonald WG, Colca JR, Kletzien RF, Finck BN. Insulin resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor γ-sparing thiazolidinedione. The Journal of Biological Chemistry. 287: 23537-48. PMID 22621923 DOI: 10.1074/jbc.M112.363960  0.4
2012 Smith GI, Reeds DN, Hall AM, Chambers KT, Finck BN, Mittendorfer B. Sexually dimorphic effect of aging on skeletal muscle protein synthesis. Biology of Sex Differences. 3: 11. PMID 22620287 DOI: 10.1186/2042-6410-3-11  0.4
2012 Hall AM, Kou K, Chen Z, Pietka TA, Kumar M, Korenblat KM, Lee K, Ahn K, Fabbrini E, Klein S, Goodwin B, Finck BN. Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver. Journal of Lipid Research. 53: 990-9. PMID 22394502 DOI: 10.1194/jlr.P025536  0.4
2011 Peterson TR, Sengupta SS, Harris TE, Carmack AE, Kang SA, Balderas E, Guertin DA, Madden KL, Carpenter AE, Finck BN, Sabatini DM. mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway. Cell. 146: 408-20. PMID 21816276 DOI: 10.1016/j.cell.2011.06.034  0.4
2011 Potthoff MJ, Boney-Montoya J, Choi M, He T, Sunny NE, Satapati S, Suino-Powell K, Xu HE, Gerard RD, Finck BN, Burgess SC, Mangelsdorf DJ, Kliewer SA. FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1α pathway. Cell Metabolism. 13: 729-38. PMID 21641554 DOI: 10.1016/j.cmet.2011.03.019  0.4
2011 Mitra MS, Schilling JD, Wang X, Jay PY, Huss JM, Su X, Finck BN. Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis. Journal of Molecular and Cellular Cardiology. 51: 120-8. PMID 21549711 DOI: 10.1016/j.yjmcc.2011.04.009  0.4
2011 Harris TE, Finck BN. Dual function lipin proteins and glycerolipid metabolism. Trends in Endocrinology and Metabolism: Tem. 22: 226-33. PMID 21470873 DOI: 10.1016/j.tem.2011.02.006  0.4
2010 Liu GH, Qu J, Carmack AE, Kim HB, Chen C, Ren H, Morris AJ, Finck BN, Harris TE. Lipin proteins form homo- and hetero-oligomers. The Biochemical Journal. 432: 65-76. PMID 20735359 DOI: 10.1042/BJ20100584  0.4
2010 Kars M, Yang L, Gregor MF, Mohammed BS, Pietka TA, Finck BN, Patterson BW, Horton JD, Mittendorfer B, Hotamisligil GS, Klein S. Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes. 59: 1899-905. PMID 20522594 DOI: 10.2337/db10-0308  0.4
2010 Kim HB, Kumar A, Wang L, Liu GH, Keller SR, Lawrence JC, Finck BN, Harris TE. Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors. Molecular and Cellular Biology. 30: 3126-39. PMID 20385772 DOI: 10.1128/MCB.01671-09  0.4
2010 Hall AM, Brunt EM, Klein S, Finck BN. Hepatic expression of cell death-inducing DFFA-like effector C in obese subjects is reduced by marked weight loss. Obesity (Silver Spring, Md.). 18: 417-9. PMID 19661960 DOI: 10.1038/oby.2009.236  0.4
2009 Shoghi KI, Finck BN, Schechtman KB, Sharp T, Herrero P, Gropler RJ, Welch MJ. In vivo metabolic phenotyping of myocardial substrate metabolism in rodents: differential efficacy of metformin and rosiglitazone monotherapy. Circulation. Cardiovascular Imaging. 2: 373-81. PMID 19808625 DOI: 10.1161/CIRCIMAGING.108.843227  0.4
2009 Potthoff MJ, Inagaki T, Satapati S, Ding X, He T, Goetz R, Mohammadi M, Finck BN, Mangelsdorf DJ, Kliewer SA, Burgess SC. FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response. Proceedings of the National Academy of Sciences of the United States of America. 106: 10853-8. PMID 19541642 DOI: 10.1073/pnas.0904187106  0.4
2009 Gropler MC, Harris TE, Hall AM, Wolins NE, Gross RW, Han X, Chen Z, Finck BN. Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice. The Journal of Biological Chemistry. 284: 6763-72. PMID 19136718 DOI: 10.1074/jbc.M807882200  0.4
2008 Chen Z, Gropler MC, Norris J, Lawrence JC, Harris TE, Finck BN. Alterations in hepatic metabolism in fld mice reveal a role for lipin 1 in regulating VLDL-triacylglyceride secretion. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1738-44. PMID 18669885 DOI: 10.1161/ATVBAHA.108.171538  0.4
2008 Shoghi KI, Gropler RJ, Sharp T, Herrero P, Fettig N, Su Y, Mitra MS, Kovacs A, Finck BN, Welch MJ. Time course of alterations in myocardial glucose utilization in the Zucker diabetic fatty rat with correlation to gene expression of glucose transporters: a small-animal PET investigation. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 1320-7. PMID 18632819 DOI: 10.2967/jnumed.108.051672  0.4
2007 Coughlin CC, Finck BN, Eagon JC, Halpin VJ, Magkos F, Mohammed BS, Klein S. Effect of marked weight loss on adiponectin gene expression and plasma concentrations. Obesity (Silver Spring, Md.). 15: 640-5. PMID 17372314 DOI: 10.1038/oby.2007.556  0.4
2007 Duncan JG, Fong JL, Medeiros DM, Finck BN, Kelly DP. Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway. Circulation. 115: 909-17. PMID 17261654 DOI: 10.1161/CIRCULATIONAHA.106.662296  0.4
2006 Schneider JG, Finck BN, Ren J, Standley KN, Takagi M, Maclean KH, Bernal-Mizrachi C, Muslin AJ, Kastan MB, Semenkovich CF. ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome. Cell Metabolism. 4: 377-89. PMID 17084711 DOI: 10.1016/j.cmet.2006.10.002  0.4
2006 Lee H, Finck BN, Jones LA, Welch MJ, Mach RH. Synthesis and evaluation of a bromine-76-labeled PPARgamma antagonist 2-bromo-5-nitro-N-phenylbenzamide. Nuclear Medicine and Biology. 33: 847-54. PMID 17045164 DOI: 10.1016/j.nucmedbio.2006.08.003  0.4
2006 Finck BN, Gropler MC, Chen Z, Leone TC, Croce MA, Harris TE, Lawrence JC, Kelly DP. Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway. Cell Metabolism. 4: 199-210. PMID 16950137 DOI: 10.1016/j.cmet.2006.08.005  0.4
2006 Burgess SC, Leone TC, Wende AR, Croce MA, Chen Z, Sherry AD, Malloy CR, Finck BN. Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice. The Journal of Biological Chemistry. 281: 19000-8. PMID 16670093 DOI: 10.1074/jbc.M600050200  0.4
2005 Park SY, Cho YR, Finck BN, Kim HJ, Higashimori T, Hong EG, Lee MK, Danton C, Deshmukh S, Cline GW, Wu JJ, Bennett AM, Rothermel B, Kalinowski A, Russell KS, et al. Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver. Diabetes. 54: 2514-24. PMID 16123338 DOI: 10.2337/diabetes.54.9.2514  0.4
2005 Finck BN, Bernal-Mizrachi C, Han DH, Coleman T, Sambandam N, LaRiviere LL, Holloszy JO, Semenkovich CF, Kelly DP. A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes. Cell Metabolism. 1: 133-44. PMID 16054054 DOI: 10.1016/j.cmet.2005.01.006  0.4
2005 Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, et al. PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. Plos Biology. 3: e101. PMID 15760270 DOI: 10.1371/journal.pbio.0030101  0.4
2004 Harris IS, Treskov I, Rowley MW, Heximer S, Kaltenbronn K, Finck BN, Gross RW, Kelly DP, Blumer KJ, Muslin AJ. G-protein signaling participates in the development of diabetic cardiomyopathy. Diabetes. 53: 3082-90. PMID 15561937 DOI: 10.2337/diabetes.53.12.3082  0.4
2003 Bernal-Mizrachi C, Weng S, Feng C, Finck BN, Knutsen RH, Leone TC, Coleman T, Mecham RP, Kelly DP, Semenkovich CF. Dexamethasone induction of hypertension and diabetes is PPAR-alpha dependent in LDL receptor-null mice. Nature Medicine. 9: 1069-75. PMID 12847522 DOI: 10.1038/nm898  0.4
2003 Finck BN, Han X, Courtois M, Aimond F, Nerbonne JM, Kovacs A, Gross RW, Kelly DP. A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content. Proceedings of the National Academy of Sciences of the United States of America. 100: 1226-31. PMID 12552126 DOI: 10.1073/pnas.0336724100  0.4
2002 Finck BN, Johnson RW. Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 282: R1429-35. PMID 11959686 DOI: 10.1152/ajpregu.00569.2001  1
2002 Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, Kovacs A, Han X, Gross RW, Kozak R, Lopaschuk GD, Kelly DP. The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. The Journal of Clinical Investigation. 109: 121-30. PMID 11781357 DOI: 10.1172/JCI14080  0.4
2000 Finck BN, Johnson RW. Tumor necrosis factor-alpha regulates secretion of the adipocyte-derived cytokine, leptin. Microscopy Research and Technique. 50: 209-15. PMID 10891886 DOI: 10.1002/1097-0029(20000801)50:3<209::AID-JEMT4>3.0.CO;2-T  1
2000 Heyen JR, Ye S, Finck BN, Johnson RW. Interleukin (IL)-10 inhibits IL-6 production in microglia by preventing activation of NF-kappaB. Brain Research. Molecular Brain Research. 77: 138-47. PMID 10814840  1
2000 Finck BN, Johnson RW. Tumor necrosis factor (TNF)-alpha induces leptin production through the p55 TNF receptor. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 278: R537-43. PMID 10666158  1
1999 Finck BN, Johnson RW. Intracerebroventricular injection of lipopolysaccharide increases plasma leptin levels. Neuroreport. 10: 153-6. PMID 10094153  1
1998 Finck BN, Kelley KW, Dantzer R, Johnson RW. In Vivo and in Vitro Evidence for the Involvement of Tumor Necrosis Factor-α in the Induction of Leptin by Lipopolysaccharide. Endocrinology. 139: 2278-2283. PMID 28200544 DOI: 10.1210/endo.139.5.6012  1
1998 Finck BN, Kelley KW, Dantzer R, Johnson RW. In vivo and in vitro evidence for the involvement of tumor necrosis factor-alpha in the induction of leptin by lipopolysaccharide. Endocrinology. 139: 2278-83. PMID 9564834 DOI: 10.1210/endo.139.5.6012  1
1997 Finck BN, Johnson RW. Anorexia, weight loss and increased plasma interleukin-6 caused by chronic intracerebroventricular infusion of interleukin-1beta in the rat. Brain Research. 761: 333-7. PMID 9252034  1
1997 Webel DM, Finck BN, Baker DH, Johnson RW. Time course of increased plasma cytokines, cortisol, and urea nitrogen in pigs following intraperitoneal injection of lipopolysaccharide. Journal of Animal Science. 75: 1514-20. PMID 9250511  0.4
1997 Finck BN, Dantzer R, Kelley KW, Woods JA, Johnson RW. Central lipopolysaccharide elevates plasma IL-6 concentration by an alpha-adrenoreceptor-mediated mechanism. The American Journal of Physiology. 272: R1880-7. PMID 9227603  1
1997 Warren EJ, Finck BN, Arkins S, Kelley KW, Scamurra RW, Murtaugh MP, Johnson RW. Coincidental changes in behavior and plasma cortisol in unrestrained pigs after intracerebroventricular injection of tumor necrosis factor-alpha. Endocrinology. 138: 2365-71. PMID 9165024 DOI: 10.1210/endo.138.6.5180  1
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