Sebastian Joyce - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Immunology, Microbiology Biology

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Postoak JL, Song W, Yang G, Guo X, Xiao S, Saffold CE, Zhang J, Joyce S, Manley NR, Wu L, Van Kaer L. Thymic epithelial cells require lipid kinase Vps34 for CD4 but not CD8 T cell selection. The Journal of Experimental Medicine. 219. PMID 35997680 DOI: 10.1084/jem.20212554  0.413
2022 Gu W, Madrid DMC, Joyce S, Driver JP. A single-cell analysis of thymopoiesis and thymic iNKT cell development in pigs. Cell Reports. 40: 111050. PMID 35793622 DOI: 10.1016/j.celrep.2022.111050  0.427
2022 Joyce S, Okoye GD, Van Kaer L. Natural Killer T Lymphocytes Integrate Innate Sensory Information and Relay Context to Effector Immune Responses. Critical Reviews in Immunology. 41: 55-88. PMID 35381143 DOI: 10.1615/CritRevImmunol.2021040076  0.403
2021 Miranda-Katz M, Erickson JJ, Lan J, Ecker A, Zhang Y, Joyce S, Williams JV. Novel HLA-B7-restricted human metapneumovirus epitopes enhance viral clearance in mice and are recognized by human CD8 T cells. Scientific Reports. 11: 20769. PMID 34675220 DOI: 10.1038/s41598-021-00023-0  0.357
2021 Joyce S, Ternette N. Know thy immune self & non-self: Proteomics informs on the expanse of self and non-self, and how and where they arise. Proteomics. e2000143. PMID 34310018 DOI: 10.1002/pmic.202000143  0.404
2020 Kumar A, Suryadevara NC, Wolf KJ, Wilson JT, Di Paolo RJ, Brien JD, Joyce S. Heterotypic immunity against vaccinia virus in an HLA-B*07:02 transgenic mousepox infection model. Scientific Reports. 10: 13167. PMID 32759969 DOI: 10.1038/S41598-020-69897-W  0.453
2020 Shae D, Baljon JJ, Wehbe M, Christov PP, Becker KW, Kumar A, Suryadevara N, Carson CS, Palmer CR, Knight FC, Joyce S, Wilson JT. Co-Delivery of Peptide Neoantigens and Stimulator of Interferon Genes (STING) Agonists Enhances Response to Cancer Vaccines. Acs Nano. PMID 32701257 DOI: 10.1021/Acsnano.0C02765  0.405
2020 Kumar A, Hill TM, Gordy LE, Suryadevara N, Wu L, Flyak AI, Bezbradica JS, Van Kaer L, Joyce S. Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 32611812 DOI: 10.1073/Pnas.2001665117  0.774
2020 Van Kaer L, Joyce S. Survivre et vivre: When iNKT cells met a Hippo. The Journal of Experimental Medicine. 217. PMID 32383750 DOI: 10.1084/Jem.20200343  0.411
2020 Bezbradica JS, Joyce S. NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release. Cell Reports. 31: 107481. PMID 32268100 DOI: 10.1016/J.Celrep.2020.03.045  0.655
2019 Joyce S, Spiller BW, Van Kaer L. What one lipid giveth, another taketh away. Nature Immunology. PMID 31636467 DOI: 10.1038/S41590-019-0525-8  0.401
2019 Knight FC, Gilchuk P, Kumar A, Becker KW, Sevimli S, Jacobson ME, Suryadevara N, Wang-Bishop L, Boyd KL, Crowe JE, Joyce S, Wilson JT. Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8 Lung-Resident Memory T Cells. Acs Nano. PMID 31553872 DOI: 10.1021/Acsnano.9B00326  0.351
2018 Wolf K, Hether T, Gilchuk P, Kumar A, Rajeh A, Schiebout C, Maybruck J, Buller RM, Ahn TH, Joyce S, DiPaolo RJ. Identifying and Tracking Low-Frequency Virus-Specific TCR Clonotypes Using High-Throughput Sequencing. Cell Reports. 25: 2369-2378.e4. PMID 30485806 DOI: 10.1016/J.Celrep.2018.11.009  0.315
2018 Yang J, Kumar A, Vilgelm AE, Chen SC, Ayers GD, Novitskiy SV, Joyce S, Richmond A. Loss of CXCR4 in Myeloid Cells Enhances Antitumor Immunity and Reduces Melanoma Growth through NK Cell and FASL Mechanisms. Cancer Immunology Research. PMID 30108045 DOI: 10.1158/2326-6066.Cir-18-0045  0.434
2018 Qiu F, Becker KW, Knight FC, Baljon JJ, Sevimli S, Shae D, Gilchuk P, Joyce S, Wilson JT. Poly(propylacrylic acid)-peptide nanoplexes as a platform for enhancing the immunogenicity of neoantigen cancer vaccines. Biomaterials. 182: 82-91. PMID 30107272 DOI: 10.1016/J.Biomaterials.2018.07.052  0.399
2018 Rogers MC, Lamens KD, Shafagati N, Johnson M, Oury TD, Joyce S, Williams JV. CD4 Regulatory T Cells Exert Differential Functions during Early and Late Stages of the Immune Response to Respiratory Viruses. Journal of Immunology (Baltimore, Md. : 1950). PMID 29997123 DOI: 10.4049/Jimmunol.1800096  0.482
2017 Kumar A, Suryadevara N, Hill TM, Bezbradica JS, Van Kaer L, Joyce S. Natural Killer T Cells: An Ecological Evolutionary Developmental Biology Perspective. Frontiers in Immunology. 8: 1858. PMID 29312339 DOI: 10.3389/Fimmu.2017.01858  0.767
2017 Kumar A, Gordy LE, Bezbradica JS, Stanic AK, Hill TM, Boothby MR, Van Kaer L, Joyce S. NF-κB Protects NKT Cells from Tumor Necrosis Factor Receptor 1-induced Death. Scientific Reports. 7: 15594. PMID 29142275 DOI: 10.1038/S41598-017-15461-Y  0.737
2017 Sevimli S, Knight FC, Gilchuk P, Joyce S, Wilson JT. Fatty Acid-Mimetic Micelles for Dual Delivery of Antigens and Imidazoquinoline Adjuvants. Acs Biomaterials Science & Engineering. 3: 179-194. PMID 29046894 DOI: 10.1021/Acsbiomaterials.6B00408  0.357
2017 Galassie AC, Goll JB, Samir P, Jensen TL, Hoek KL, Howard LM, Allos TM, Niu X, Gordy LE, Creech CB, Hill H, Joyce S, Edwards KM, Link AJ. Proteomics show antigen presentation processes in human immune cells after AS03-H5N1 vaccination. Proteomics. PMID 28508465 DOI: 10.1002/Pmic.201600453  0.404
2017 Kumar A, Bezbradica JS, Stanic AK, Joyce S. Characterization and Functional Analysis of Mouse Semi-invariant Natural T Cells. Current Protocols in Immunology. 117: 14.13.1-14.13.55. PMID 28369682 DOI: 10.1002/Cpim.22  0.769
2017 Gilchuk P, Knight FC, Wilson JT, Joyce S. Eliciting Epitope-Specific CD8+ T Cell Response by Immunization with Microbial Protein Antigens Formulated with α-Galactosylceramide: Theory, Practice, and Protocols. Methods in Molecular Biology (Clifton, N.J.). 1494: 321-352. PMID 27718206 DOI: 10.1007/978-1-4939-6445-1_25  0.472
2017 Galassie AC, Goll JB, Samir P, Jensen TL, Hoek KL, Howard LM, Allos TM, Niu X, Gordy LE, Creech CB, Hill H, Joyce S, Edwards KM, Link AJ. Front Cover: Proteomics show antigen presentation processes in human immune cells after AS03-H5N1 vaccination Proteomics. 17: 1770101. DOI: 10.1002/Pmic.201770101  0.344
2016 Li B, Siuta M, Bright V, Koktysh D, Matlock BK, Dumas ME, Zhu M, Holt A, Stec D, Deng S, Savage PB, Joyce S, Pham W. Improved proliferation of antigen-specific cytolytic T lymphocytes using a multimodal nanovaccine. International Journal of Nanomedicine. 11: 6103-6121. PMID 27895483 DOI: 10.2147/Ijn.S112432  0.404
2016 Van Kaer L, Wu L, Joyce S. Mechanisms and Consequences of Antigen Presentation by CD1. Trends in Immunology. PMID 27623113 DOI: 10.1016/J.It.2016.08.011  0.409
2016 Gilchuk P, Hill TM, Guy C, McMaster SR, Boyd KL, Rabacal WA, Lu P, Shyr Y, Kohlmeier JE, Sebzda E, Green DR, Joyce S. A Distinct Lung-Interstitium-Resident Memory CD8(+) T Cell Subset Confers Enhanced Protection to Lower Respiratory Tract Infection. Cell Reports. PMID 27498869 DOI: 10.1016/J.Celrep.2016.07.037  0.408
2016 Hastings AK, Gilchuk P, Joyce S, Williams JV. Novel HLA-A2-restricted human metapneumovirus epitopes reduce viral titers in mice and are recognized by human T cells. Vaccine. PMID 27105560 DOI: 10.1016/J.Vaccine.2016.04.034  0.408
2015 Spencer CT, Bezbradica JS, Ramos MG, Arico CD, Conant SB, Gilchuk P, Gray JJ, Zheng M, Niu X, Hildebrand W, Link AJ, Joyce S. Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules. Proteomics. Clinical Applications. 9: 1035-52. PMID 26768311 DOI: 10.1002/Prca.201500106  0.702
2015 Joyce S. Immunoproteasomes edit tumors, which then escapes immune recognition. European Journal of Immunology. 45: 3241-5. PMID 26527367 DOI: 10.1002/Eji.201546100  0.433
2015 Erickson JJ, Lu P, Wen S, Hastings AK, Gilchuk P, Joyce S, Shyr Y, Williams JV. Acute Viral Respiratory Infection Rapidly Induces a CD8+ T Cell Exhaustion-like Phenotype. Journal of Immunology (Baltimore, Md. : 1950). PMID 26401005 DOI: 10.4049/Jimmunol.1403004  0.369
2015 Stengel KR, Zhao Y, Klus NJ, Kaiser JF, Gordy LE, Joyce S, Hiebert SW, Summers AR. Histone Deacetylase 3 Is Required for Efficient T Cell Development. Molecular and Cellular Biology. 35: 3854-65. PMID 26324326 DOI: 10.1128/Mcb.00706-15  0.438
2015 Hill TM, Gilchuk P, Cicek BB, Osina MA, Boyd KL, Durrant DM, Metzger DW, Khanna KM, Joyce S. Border Patrol Gone Awry: Lung NKT Cell Activation by Francisella tularensis Exacerbates Tularemia-Like Disease. Plos Pathogens. 11: e1004975. PMID 26068662 DOI: 10.1371/Journal.Ppat.1004975  0.432
2015 Wen SC, Schuster JE, Gilchuk P, Boyd KL, Joyce S, Williams JV. Lung CD8+ T Cell Impairment Occurs during Human Metapneumovirus Infection despite Virus-Like Particle Induction of Functional CD8+ T Cells. Journal of Virology. 89: 8713-26. PMID 26063431 DOI: 10.1128/Jvi.00670-15  0.388
2015 Hoek KL, Samir P, Howard LM, Niu X, Prasad N, Galassie A, Liu Q, Allos TM, Floyd KA, Guo Y, Shyr Y, Levy SE, Joyce S, Edwards KM, Link AJ. A cell-based systems biology assessment of human blood to monitor immune responses after influenza vaccination. Plos One. 10: e0118528. PMID 25706537 DOI: 10.1371/Journal.Pone.0118528  0.408
2015 Gilchuk P, Hill TM, Wilson JT, Joyce S. Discovering protective CD8 T cell epitopes--no single immunologic property predicts it! Current Opinion in Immunology. 34: 43-51. PMID 25660347 DOI: 10.1016/J.Coi.2015.01.013  0.406
2015 Hastings AK, Erickson JJ, Schuster JE, Boyd KL, Tollefson SJ, Johnson M, Gilchuk P, Joyce S, Williams JV. Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication. Journal of Virology. 89: 4405-20. PMID 25653440 DOI: 10.1128/Jvi.03275-14  0.446
2014 Yang J, Hawkins OE, Barham W, Gilchuk P, Boothby M, Ayers GD, Joyce S, Karin M, Yull FE, Richmond A. Myeloid IKKβ promotes antitumor immunity by modulating CCL11 and the innate immune response. Cancer Research. 74: 7274-84. PMID 25336190 DOI: 10.1158/0008-5472.Can-14-1091  0.487
2014 Wen SC, Tollefson SJ, Johnson M, Gilchuk P, Boyd KL, Shepherd B, Joyce S, Williams JV. Acute clearance of human metapneumovirus occurs independently of natural killer cells. Journal of Virology. 88: 10963-9. PMID 24965465 DOI: 10.1128/Jvi.01558-14  0.452
2013 Gilchuk P, Spencer CT, Conant SB, Hill T, Gray JJ, Niu X, Zheng M, Erickson JJ, Boyd KL, McAfee KJ, Oseroff C, Hadrup SR, Bennink JR, Hildebrand W, Edwards KM, ... ... Joyce S, et al. Discovering naturally processed antigenic determinants that confer protective T cell immunity. The Journal of Clinical Investigation. 123: 1976-87. PMID 23543059 DOI: 10.1172/Jci67388  0.44
2013 Spencer CT, Dragovic SM, Conant SB, Gray JJ, Zheng M, Samir P, Niu X, Moutaftsi M, Van Kaer L, Sette A, Link AJ, Joyce S. Sculpting MHC class II-restricted self and non-self peptidome by the class I Ag-processing machinery and its impact on Th-cell responses. European Journal of Immunology. 43: 1162-72. PMID 23386199 DOI: 10.1002/Eji.201243087  0.809
2012 Bright VR, Gilchuk P, Gordy L, Flyak A, Joyce S, Yankeelov T, Pham W. Abstract 1964: Development of a nanovaccine for cancer therapy Cancer Research. 72: 1964-1964. DOI: 10.1158/1538-7445.Am2012-1964  0.345
2011 Gordy LE, Bezbradica JS, Flyak AI, Spencer CT, Dunkle A, Sun J, Stanic AK, Boothby MR, He YW, Zhao Z, Van Kaer L, Joyce S. IL-15 regulates homeostasis and terminal maturation of NKT cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 6335-45. PMID 22084435 DOI: 10.4049/Jimmunol.1003965  0.747
2011 Joyce S, Girardi E, Zajonc DM. NKT cell ligand recognition logic: molecular basis for a synaptic duet and transmission of inflammatory effectors. Journal of Immunology (Baltimore, Md. : 1950). 187: 1081-9. PMID 21772035 DOI: 10.4049/Jimmunol.1001910  0.534
2011 Dragovic SM, Hill T, Christianson GJ, Kim S, Elliott T, Scott D, Roopenian DC, Van Kaer L, Joyce S. Proteasomes, TAP, and endoplasmic reticulum-associated aminopeptidase associated with antigen processing control CD4+ Th cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigens. Journal of Immunology (Baltimore, Md. : 1950). 186: 6683-92. PMID 21572029 DOI: 10.4049/Jimmunol.1100525  0.785
2011 Aiken C, Joyce S. Immunology: TRIM5 does double duty. Nature. 472: 305-6. PMID 21512569 DOI: 10.1038/472305A  0.322
2011 Boelte KC, Gordy LE, Joyce S, Thompson MA, Yang L, Lin PC. Rgs2 mediates pro-angiogenic function of myeloid derived suppressor cells in the tumor microenvironment via upregulation of MCP-1. Plos One. 6: e18534. PMID 21494556 DOI: 10.1371/Journal.Pone.0018534  0.316
2010 Van Kaer L, Joyce S. The hunt for iNKT cell antigens: alpha-galactosidase-deficient mice to the rescue? Immunity. 33: 143-5. PMID 20732635 DOI: 10.1016/J.Immuni.2010.08.009  0.473
2010 Hoek KL, Gordy LE, Collins PL, Parekh VV, Aune TM, Joyce S, Thomas JW, Van Kaer L, Sebzda E. Follicular B cell trafficking within the spleen actively restricts humoral immune responses. Immunity. 33: 254-65. PMID 20691614 DOI: 10.1016/J.Immuni.2010.07.016  0.47
2010 Lee K, Gudapati P, Dragovic S, Spencer C, Joyce S, Killeen N, Magnuson MA, Boothby M. Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways. Immunity. 32: 743-53. PMID 20620941 DOI: 10.1016/J.Immuni.2010.06.002  0.799
2010 Spencer CT, Gilchuk P, Dragovic SM, Joyce S. Minor histocompatibility antigens: presentation principles, recognition logic and the potential for a healing hand. Current Opinion in Organ Transplantation. 15: 512-25. PMID 20616723 DOI: 10.1097/Mot.0B013E32833C1552  0.79
2010 Joyce S, Gordy LE. Natural killer T cell-a cat o' nine lives! The Embo Journal. 29: 1475-6. PMID 20442728 DOI: 10.1038/Emboj.2010.66  0.521
2010 Escande-Beillard N, Washburn L, Zekzer D, Wu ZP, Eitan S, Ivkovic S, Lu Y, Dang H, Middleton B, Bilousova TV, Yoshimura Y, Evans CJ, Joyce S, Tian J, Kaufman DL. Neurons preferentially respond to self-MHC class I allele products regardless of peptide presented. Journal of Immunology (Baltimore, Md. : 1950). 184: 816-23. PMID 20018625 DOI: 10.4049/Jimmunol.0902159  0.394
2009 Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, ... ... Joyce S, et al. Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. The Embo Journal. 28: 3781. PMID 19953109 DOI: 10.1038/Emboj.2009.348  0.4
2009 Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, ... ... Joyce S, et al. Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. The Embo Journal. 28: 3579-90. PMID 19816402 DOI: 10.1038/Emboj.2009.286  0.362
2008 Florence WC, Bhat RK, Joyce S. CD1d-restricted glycolipid antigens: presentation principles, recognition logic and functional consequences. Expert Reviews in Molecular Medicine. 10: e20. PMID 18601810 DOI: 10.1017/S1462399408000732  0.532
2008 Joyce S, Van Kaer L. Lung NKT cell commotion takes your breath away. Nature Medicine. 14: 609-10. PMID 18535574 DOI: 10.1038/Nm0608-609  0.331
2008 Ni CY, Wu ZH, Florence WC, Parekh VV, Arrate MP, Pierce S, Schweitzer B, Van Kaer L, Joyce S, Miyamoto S, Ballard DW, Oltz EM. Cutting edge: K63-linked polyubiquitination of NEMO modulates TLR signaling and inflammation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 180: 7107-11. PMID 18490708 DOI: 10.4049/Jimmunol.180.11.7107  0.333
2008 Joyce S, Van Kaer L. Invariant natural killer T cells trigger adaptive lymphocytes to churn up bile. Cell Host & Microbe. 3: 275-7. PMID 18474352 DOI: 10.1016/J.Chom.2008.04.007  0.487
2008 Villarino AV, Artis D, Bezbradica JS, Miller O, Saris CJM, Joyce S, Hunter CA. IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD International Immunology. 20: 739-752. PMID 18375937 DOI: 10.1093/Intimm/Dxn032  0.682
2007 Torres VJ, Stauff DL, Pishchany G, Bezbradica JS, Gordy LE, Iturregui J, Anderson KL, Dunman PM, Joyce S, Skaar EP. A Staphylococcus aureus regulatory system that responds to host heme and modulates virulence. Cell Host & Microbe. 1: 109-19. PMID 18005689 DOI: 10.1016/J.Chom.2007.03.001  0.661
2007 Jing Y, Gravenstein S, Chaganty NR, Chen N, Lyerly KH, Joyce S, Deng Y. Aging is associated with a rapid decline in frequency, alterations in subset composition, and enhanced Th2 response in CD1d-restricted NKT cells from human peripheral blood. Experimental Gerontology. 42: 719-32. PMID 17368996 DOI: 10.1016/J.Exger.2007.01.009  0.458
2006 Bezbradica JS, Stanic AK, Joyce S. Characterization and functional analysis of mouse invariant natural T (iNKT) cells. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 14.13. PMID 18432968 DOI: 10.1002/0471142735.Im1413S73  0.75
2006 Bezbradica JS, Gordy LE, Stanic AK, Dragovic S, Hill T, Hawiger J, Unutmaz D, Van Kaer L, Joyce S. Granulocyte-macrophage colony-stimulating factor regulates effector differentiation of invariant natural killer T cells during thymic ontogeny. Immunity. 25: 487-97. PMID 16949316 DOI: 10.1016/J.Immuni.2006.06.017  0.795
2006 Van Kaer L, Joyce S. Viral evasion of antigen presentation: not just for peptides anymore. Nature Immunology. 7: 795-7. PMID 16855602 DOI: 10.1038/Ni0806-795  0.401
2006 Major AS, Singh RR, Joyce S, Van Kaer L. The role of invariant natural killer T cells in lupus and atherogenesis. Immunologic Research. 34: 49-66. PMID 16720898 DOI: 10.1385/Ir:34:1:49  0.473
2006 Major AS, Joyce S, Van Kaer L. Lipid metabolism, atherogenesis and CD1-restricted antigen presentation. Trends in Molecular Medicine. 12: 270-8. PMID 16651026 DOI: 10.1016/J.Molmed.2006.04.004  0.388
2006 Yan J, Parekh VV, Mendez-Fernandez Y, Olivares-Villagómez D, Dragovic S, Hill T, Roopenian DC, Joyce S, Van Kaer L. In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules. The Journal of Experimental Medicine. 203: 647-59. PMID 16505142 DOI: 10.1084/Jem.20052271  0.803
2005 Parekh VV, Wilson MT, Olivares-Villagómez D, Singh AK, Wu L, Wang CR, Joyce S, Van Kaer L. Glycolipid antigen induces long-term natural killer T cell anergy in mice. The Journal of Clinical Investigation. 115: 2572-83. PMID 16138194 DOI: 10.1172/Jci24762  0.53
2005 Van Kaer L, Joyce S. Innate immunity: NKT cells in the spotlight. Current Biology : Cb. 15: R429-31. PMID 15936267 DOI: 10.1016/J.Cub.2005.05.032  0.437
2005 Bezbradica JS, Stanic AK, Matsuki N, Bour-Jordan H, Bluestone JA, Thomas JW, Unutmaz D, Van Kaer L, Joyce S. Distinct roles of dendritic cells and B cells in Va14Ja18 natural T cell activation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 174: 4696-705. PMID 15814694 DOI: 10.4049/Jimmunol.174.8.4696  0.773
2005 Bezbradica JS, Hill T, Stanic AK, Van Kaer L, Joyce S. Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny. Proceedings of the National Academy of Sciences of the United States of America. 102: 5114-9. PMID 15792999 DOI: 10.1073/Pnas.0408449102  0.702
2005 Singh AK, Yang JQ, Parekh VV, Wei J, Wang CR, Joyce S, Singh RR, Van Kaer L. The natural killer T cell ligand alpha-galactosylceramide prevents or promotes pristane-induced lupus in mice. European Journal of Immunology. 35: 1143-54. PMID 15761849 DOI: 10.1002/Eji.200425861  0.431
2004 Major AS, Wilson MT, McCaleb JL, Ru Su Y, Stanic AK, Joyce S, Van Kaer L, Fazio S, Linton MF. Quantitative and qualitative differences in proatherogenic NKT cells in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 2351-7. PMID 15472130 DOI: 10.1161/01.Atv.0000147112.84168.87  0.536
2004 Parekh VV, Singh AK, Wilson MT, Olivares-Villagómez D, Bezbradica JS, Inazawa H, Ehara H, Sakai T, Serizawa I, Wu L, Wang CR, Joyce S, Van Kaer L. Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids. Journal of Immunology (Baltimore, Md. : 1950). 173: 3693-706. PMID 15356115 DOI: 10.4049/Jimmunol.173.6.3693  0.756
2004 Saito T, Okumura A, Watanabe H, Asano M, Ishida-Okawara A, Sakagami J, Sudo K, Hatano-Yokoe Y, Bezbradica JS, Joyce S, Abo T, Iwakura Y, Suzuki K, Yamagoe S. Increase in hepatic NKT cells in leukocyte cell-derived chemotaxin 2-deficient mice contributes to severe concanavalin A-induced hepatitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 579-85. PMID 15210819 DOI: 10.4049/Jimmunol.173.1.579  0.739
2004 Yoshimura Y, Yadav R, Christianson GJ, Ajayi WU, Roopenian DC, Joyce S. Duration of alloantigen presentation and avidity of T cell antigen recognition correlate with immunodominance of CTL response to minor histocompatibility antigens. Journal of Immunology (Baltimore, Md. : 1950). 172: 6666-74. PMID 15153482 DOI: 10.4049/Jimmunol.172.11.6666  0.407
2004 Takagi D, Iwabuchi K, Iwabuchi C, Nakamaru Y, Maguchi S, Ohwatari R, Furuta Y, Fukuda S, Joyce S, Onoé K. Immunoregulatory defects of Vα24+Vβ11+ NKT cells in development of Wegener's granulomatosis and relapsing polychondritis Clinical and Experimental Immunology. 136: 591-600. PMID 15147365 DOI: 10.1111/J.1365-2249.2004.02471.X  0.437
2004 Nakai Y, Iwabuchi K, Fujii S, Ishimori N, Dashtsoodol N, Watano K, Mishima T, Iwabuchi C, Tanaka S, Bezbradica JS, Nakayama T, Taniguchi M, Miyake S, Yamamura T, Kitabatake A, ... Joyce S, et al. Natural killer T cells accelerate atherogenesis in mice. Blood. 104: 2051-9. PMID 15113755 DOI: 10.1182/Blood-2003-10-3485  0.706
2004 Stanic AK, Bezbradica JS, Park JJ, Van Kaer L, Boothby MR, Joyce S. Cutting edge: the ontogeny and function of Va14Ja18 natural T lymphocytes require signal processing by protein kinase C theta and NF-kappa B. Journal of Immunology (Baltimore, Md. : 1950). 172: 4667-71. PMID 15067039 DOI: 10.4049/Jimmunol.172.8.4667  0.776
2004 Stanic AK, Bezbradica JS, Park JJ, Matsuki N, Mora AL, Van Kaer L, Boothby MR, Joyce S. NF-kappa B controls cell fate specification, survival, and molecular differentiation of immunoregulatory natural T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 172: 2265-73. PMID 14764695 DOI: 10.4049/Jimmunol.172.4.2265  0.78
2004 Park JJ, Kang SJ, De Silva AD, Stanic AK, Casorati G, Hachey DL, Cresswell P, Joyce S. Lipid-protein interactions: biosynthetic assembly of CD1 with lipids in the endoplasmic reticulum is evolutionarily conserved. Proceedings of the National Academy of Sciences of the United States of America. 101: 1022-6. PMID 14722359 DOI: 10.1073/Pnas.0307847100  0.582
2004 Hill T, Joyce S. Another cause for incompatibility: gestational priming of women by tissue antigens of men Blood. 103: 1570-1571. DOI: 10.1182/Blood-2003-12-4418  0.384
2003 Zhang F, Liang Z, Matsuki N, Van Kaer L, Joyce S, Wakeland EK, Aune TM. A murine locus on chromosome 18 controls NKT cell homeostasis and Th cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 171: 4613-20. PMID 14568935 DOI: 10.4049/Jimmunol.171.9.4613  0.413
2003 Stanic AK, Shashidharamurthy R, Bezbradica JS, Matsuki N, Yoshimura Y, Miyake S, Choi EY, Schell TD, Van Kaer L, Tevethia SS, Roopenian DC, Yamamura T, Joyce S. Another view of T cell antigen recognition: cooperative engagement of glycolipid antigens by Va14Ja18 natural T(iNKT) cell receptor [corrected]. Journal of Immunology (Baltimore, Md. : 1950). 171: 4539-51. PMID 14568927 DOI: 10.4049/Jimmunol.171.9.4539  0.767
2003 Wilson MT, Johansson C, Olivares-Villagómez D, Singh AK, Stanic AK, Wang CR, Joyce S, Wick MJ, Van Kaer L. The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion. Proceedings of the National Academy of Sciences of the United States of America. 100: 10913-8. PMID 12960397 DOI: 10.1073/Pnas.1833166100  0.533
2003 Mora AL, Corn RA, Stanic AK, Goenka S, Aronica M, Stanley S, Ballard DW, Joyce S, Boothby M. Antiapoptotic function of NF-κB in T lymphocytes is influenced by their differentiation status: roles of Fas, c-FLIP, and Bcl-xL Cell Death & Differentiation. 10: 1032-1044. PMID 12934078 DOI: 10.1038/Sj.Cdd.4401257  0.354
2003 Yang JQ, Singh AK, Wilson MT, Satoh M, Stanic AK, Park JJ, Hong S, Gadola SD, Mizutani A, Kakumanu SR, Reeves WH, Cerundolo V, Joyce S, Van Kaer L, Singh RR. Immunoregulatory role of CD1d in the hydrocarbon oil-induced model of lupus nephritis. Journal of Immunology (Baltimore, Md. : 1950). 171: 2142-53. PMID 12902521 DOI: 10.4049/Jimmunol.171.4.2142  0.673
2003 Yang J, Jaramillo A, Liu W, Olack B, Yoshimura Y, Joyce S, Kaleem Z, Mohanakumar T. Chronic rejection of murine cardiac allografts discordant at the H13 minor histocompatibility antigen correlates with the generation of the H13-specific CD8+ cytotoxic T cells. Transplantation. 76: 84-91. PMID 12865791 DOI: 10.1097/01.Tp.0000072013.21336.64  0.361
2003 Motsinger A, Azimzadeh A, Stanic AK, Johnson RP, Van Kaer L, Joyce S, Unutmaz D. Identification and simian immunodeficiency virus infection of CD1d-restricted macaque natural killer T cells. Journal of Virology. 77: 8153-8. PMID 12829854 DOI: 10.1128/Jvi.77.14.8153-8158.2003  0.474
2003 Matsuki N, Stanic AK, Embers ME, Van Kaer L, Morel L, Joyce S. Genetic dissection of V alpha 14J alpha 18 natural T cell number and function in autoimmune-prone mice. Journal of Immunology (Baltimore, Md. : 1950). 170: 5429-37. PMID 12759418 DOI: 10.4049/Jimmunol.170.11.5429  0.443
2003 Stanic AK, Park JJ, Joyce S. Innate self recognition by an invariant, rearranged T-cell receptor and its immune consequences. Immunology. 109: 171-84. PMID 12757612 DOI: 10.1046/J.1365-2567.2003.01657.X  0.671
2003 Yadav R, Yoshimura Y, Boesteanu A, Christianson GJ, Ajayi WU, Shashidharamurthy R, Stanic AK, Roopenian DC, Joyce S. The H4b minor histocompatibility antigen is caused by a combination of genetically determined and posttranslational modifications. Journal of Immunology (Baltimore, Md. : 1950). 170: 5133-42. PMID 12734360 DOI: 10.4049/Jimmunol.170.10.5133  0.354
2003 Chun T, Page MJ, Gapin L, Matsuda JL, Xu H, Nguyen H, Kang HS, Stanic AK, Joyce S, Koltun WA, Chorney MJ, Kronenberg M, Wang CR. CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells. The Journal of Experimental Medicine. 197: 907-18. PMID 12682110 DOI: 10.1084/Jem.20021366  0.51
2003 Yang L, Yamagata N, Yadav R, Brandon S, Courtney RL, Morrow JD, Shyr Y, Boothby M, Joyce S, Carbone DP, Breyer RM. Cancer-associated immunodeficiency and dendritic cell abnormalities mediated by the prostaglandin EP2 receptor. The Journal of Clinical Investigation. 111: 727-35. PMID 12618527 DOI: 10.1172/Jci16492  0.454
2003 Stanic AK, De Silva AD, Park JJ, Sriram V, Ichikawa S, Hirabyashi Y, Hayakawa K, Van Kaer L, Brutkiewicz RR, Joyce S. Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by beta-D-glucosylceramide synthase deficiency. Proceedings of the National Academy of Sciences of the United States of America. 100: 1849-54. PMID 12576547 DOI: 10.1073/Pnas.0430327100  0.58
2003 Joyce S, Van Kaer L. CD1-restricted antigen presentation: an oily matter. Current Opinion in Immunology. 15: 95-104. PMID 12495740 DOI: 10.1016/S0952-7915(02)00012-2  0.417
2002 Choi EY, Christianson GJ, Yoshimura Y, Sproule TJ, Jung N, Joyce S, Roopenian DC. Immunodominance of H60 is caused by an abnormally high precursor T cell pool directed against its unique minor histocompatibility antigen peptide. Immunity. 17: 593-603. PMID 12433366 DOI: 10.1016/S1074-7613(02)00428-4  0.405
2002 Choi EY, Christianson GJ, Yoshimura Y, Jung N, Sproule TJ, Malarkannan S, Joyce S, Roopenian DC. Real-time T-cell profiling identifies H60 as a major minor histocompatibility antigen in murine graft-versus-host disease. Blood. 100: 4259-65. PMID 12393464 DOI: 10.1182/Blood-2002-05-1299  0.44
2002 Schell TD, Mylin LM, Tevethia SS, Joyce S. The assembly of functional beta(2)-microglobulin-free MHC class I molecules that interact with peptides and CD8(+) T lymphocytes. International Immunology. 14: 775-82. PMID 12096037 DOI: 10.1093/Intimm/Dxf041  0.369
2002 Motsinger A, Haas DW, Stanic AK, Van Kaer L, Joyce S, Unutmaz D. CD1d-restricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infection. The Journal of Experimental Medicine. 195: 869-79. PMID 11927631 DOI: 10.1084/Jem.20011712  0.432
2002 De Silva AD, Park JJ, Matsuki N, Stanic AK, Brutkiewicz RR, Medof ME, Joyce S. Lipid protein interactions: the assembly of CD1d1 with cellular phospholipids occurs in the endoplasmic reticulum. Journal of Immunology (Baltimore, Md. : 1950). 168: 723-33. PMID 11777966 DOI: 10.4049/Jimmunol.168.2.723  0.596
2002 Singh AK, Wilson MT, Hong S, Olivares-Villagómez D, Du C, Stanic AK, Joyce S, Sriram S, Koezuka Y, Van Kaer L. Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 194: 1801-11. PMID 11748281 DOI: 10.1084/Jem.194.12.1801  0.495
2001 Serreze DV, Johnson EA, Chapman HD, Graser RT, Marron MP, DiLorenzo TP, Silveira P, Yoshimura Y, Nathenson SG, Joyce S. Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool. Diabetes. 50: 1992-2000. PMID 11522664 DOI: 10.2337/Diabetes.50.9.1992  0.516
2001 Joyce S. Immune recognition, response, and regulation: How T lymphocytes do it Immunologic Research. 23: 215-228. PMID 11444386 DOI: 10.1385/Ir:23:2-3:215  0.489
2001 Joyce S. CD1d and natural T cells: How their properties jump-start the immune system Cellular and Molecular Life Sciences. 58: 442-469. PMID 11315191 DOI: 10.1007/Pl00000869  0.501
2001 Eun Young Choi, Yoshimura Y, Christianson GJ, Sproule TJ, Malarkannan S, Shastri N, Joyce S, Roopenian DC. Quantitative analysis of the immune response to mouse non-MHC transplantation antigens in vivo: The H60 histocompatibility antigen dominates over all others Journal of Immunology. 166: 4370-4379. PMID 11254691 DOI: 10.4049/Jimmunol.166.7.4370  0.361
2001 Joyce S. Dx: leukemia; Rx: CD8+ NKT cell transplantation Blood. 97: 2921-2922. DOI: 10.1182/Blood.V97.10.2921B  0.334
2000 Mylin LM, Schell TD, Roberts D, Epler M, Boesteanu A, Collins EJ, Frelinger JA, Joyce S, Tevethia SS. Quantitation of CD8+ T-lymphocyte responses to multiple epitopes from simian virus 40 (SV40) large T antigen in C57BL/6 mice immunized with SV40, SV40 T-antigen-transformed cells, or vaccinia virus recombinants expressing full-length T antigen or epitope minigenes Journal of Virology. 74: 6922-6934. PMID 10888631 DOI: 10.1128/Jvi.74.15.6922-6934.2000  0.479
2000 Joyce S. Natural T cells: Cranking up the immune system by prompt cytokine secretion Proceedings of the National Academy of Sciences of the United States of America. 97: 6933-6935. PMID 10860950 DOI: 10.1073/Pnas.97.13.6933  0.37
2000 Kennedy MK, Glaccum M, Brown SN, Butz EA, Viney JL, Embers M, Matsuki N, Charrier K, Sedger L, Willis CR, Brasel K, Morrissey PJ, Stocking K, Schuh JC, Joyce S, et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. The Journal of Experimental Medicine. 191: 771-80. PMID 10704459 DOI: 10.1084/Jem.191.5.771  0.384
1998 Goyarts EC, Vegh Z, Kalergis AM, Hörig H, Papadopoulos NJ, Young AC, Thomson CT, Chang HC, Joyce S, Nathenson SG. Point mutations in the beta chain CDR3 can alter the T cell receptor recognition pattern on an MHC class I/peptide complex over a broad interface area. Molecular Immunology. 35: 593-607. PMID 9823758 DOI: 10.1016/S0161-5890(98)00056-X  0.363
1998 Joyce S, Woods AS, Yewdell JW, Bennink JR, De Silva AD, Boesteanu A, Balk SP, Cotter RJ, Brutkiewicz RR. Natural ligand of mouse CD1d1: Cellular glycosylphosphatidylinositol Science. 279: 1541-1544. PMID 9488653 DOI: 10.1126/Science.279.5356.1541  0.446
1997 Boesteanu A, Silva ADD, Nakajima H, Leonard WJ, Peschon JJ, Joyce S. Distinct Roles for Signals Relayed through the Common Cytokine Receptor γ Chain and Interleukin 7 Receptor α Chain in Natural T Cell Development Journal of Experimental Medicine. 186: 331-336. PMID 9221763 DOI: 10.1084/Jem.186.2.331  0.459
1997 Mendiratta SK, Martin WD, Hong S, Boesteanu A, Joyce S, Van Kaer L. CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity. 6: 469-77. PMID 9133426 DOI: 10.1016/S1074-7613(00)80290-3  0.521
1997 Joyce S. Traffic control of completely assembled MHC class I molecules beyond the endoplasmic reticulum Journal of Molecular Biology. 266: 993-1001. PMID 9086276 DOI: 10.1006/Jmbi.1996.0822  0.366
1996 Joyce S, Nathenson SG. Alloreactivity, antigen recognition and T-cell selection: Three diverse T-cell recognition problems with a common solution Immunological Reviews. 59-103. PMID 9034864 DOI: 10.1111/J.1600-065X.1996.Tb00930.X  0.448
1996 Joyce S, Negishi I, Boesteanu A, DeSilva AD, Sharma P, Chorney MJ, Loh DY, Van Kaer L. Expansion of natural (NK1+) T cells that express αβ T cell receptors in transporters associated with antigen presentation-1 null and thymus leukemia antigen positive mice Journal of Experimental Medicine. 184: 1579-1584. PMID 8879233 DOI: 10.1084/Jem.184.4.1579  0.525
1994 Joyce S, Tabaczewski P, Angeletti RH, Nathenson SG, Stroynowski I. A nonpolymorphic major histocompatibility complex class Ib molecule binds a large array of diverse self-peptides. The Journal of Experimental Medicine. 179: 579-88. PMID 8294869 DOI: 10.1084/Jem.179.2.579  0.346
1994 Joyce S, Kuzushima K, Kepecs G, Angeletti RH, Nathenson SG. Characterization of an incompletely assembled major histocompatibility class I molecule (H-2Kb) associated with unusually long peptides: implications for antigen processing and presentation. Proceedings of the National Academy of Sciences of the United States of America. 91: 4145-9. PMID 8183884 DOI: 10.1073/Pnas.91.10.4145  0.356
1994 Joyce S, Nathenson SG. Methods to study peptides associated with MHC class I molecules Current Opinion in Immunology. 6: 24-31. PMID 7513524 DOI: 10.1016/0952-7915(94)90029-9  0.408
1992 Joyce S, Sun R, Nathenson SG. Mapping the orientation of an antigenic peptide bound in the antigen binding groove of H-2Kb using a monoclonal antibody Biochemical and Biophysical Research Communications. 186: 1449-1454. PMID 1380802 DOI: 10.1016/S0006-291X(05)81569-4  0.382
1992 Shibata K, Imarai M, van Bleek GM, Joyce S, Nathenson SG. Vesicular stomatitis virus antigenic octapeptide N52-59 is anchored into the groove of the H-2Kb molecule by the side chains of three amino acids and the main-chain atoms of the amino terminus. Proceedings of the National Academy of Sciences of the United States of America. 89: 3135-9. PMID 1313583 DOI: 10.1073/Pnas.89.7.3135  0.309
1991 Nathenson SG, Van Bleek GM, Geliebter J, Hasenkrug K, Imarai M, Joyce S, Kesari K, Kumar A, McCue B, Nakagawa M, Palmieri E, Sheil J, Shibata K, Sun R, Zhang W. Specificity of interaction between MHC (major histocompatibility complex) class I molecules, antigenic peptides, and the T cell receptor Developmental and Comparative Immunology. 15. DOI: 10.1016/0145-305X(91)90201-9  0.447
1988 Joyce S, Flye MW, Mohanakumar T. Characterization of kidney cell-specific, non-major histocompatibility complex alloantigen using antibodies eluted from rejected human renal allografts Transplantation. 46: 362-367. PMID 3047925 DOI: 10.1097/00007890-198809000-00006  0.375
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