Gary B. Huffnagle - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Microbiology Biology

187 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Dickson RP, Huffnagle GB, Flaherty KR, White ES, Martinez FJ, Erb-Downward JR, Moore BB, O'Dwyer DN. Radiographic Honeycombing and Altered Lung Microbiota in Patients with Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 31419390 DOI: 10.1164/rccm.201903-0680LE  1
2019 O'Dwyer DN, Ashley SL, Gurczynski SJ, Xia M, Wilke C, Falkowski NR, Norman KC, Arnold KB, Huffnagle GB, Salisbury ML, Han MK, Flaherty KR, White ES, Martinez FJ, Erb-Downward JR, et al. Lung Microbiota Contribute to Pulmonary Inflammation and Disease Progression in Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 30789747 DOI: 10.1164/rccm.201809-1650OC  1
2018 Pendleton KM, Dickson RP, Newton DW, Hoffman TC, Yanik GA, Huffnagle GB. Respiratory Tract Colonization by species Portends Worse Outcomes in Immunocompromised Patients. Clinical Pulmonary Medicine. 25: 197-201. PMID 30911217 DOI: 10.1097/CPM.0000000000000279  0.72
2018 Fillion-Bertrand G, Dickson RP, Boivin R, Lavoie JP, Huffnagle GB, Leclere M. Lung Microbiome is Influenced by the Environment and Asthmatic Status in an Equine Model of Asthma. American Journal of Respiratory Cell and Molecular Biology. PMID 30183323 DOI: 10.1165/rcmb.2017-0228OC  0.72
2018 Diao W, Shen N, Du Y, Erb-Downward JR, Sun X, Guo C, Ke Q, Huffnagle GB, Gyetko MR, He B. Symptom-related sputum microbiota in stable chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease. 13: 2289-2299. PMID 30104869 DOI: 10.2147/COPD.S167618  1
2018 O'Dwyer DN, Zhou X, Wilke CA, Xia M, Falkowski NR, Norman KC, Arnold KB, Huffnagle GB, Murray S, Erb-Downward JR, Yanik GA, Moore BB, Dickson RP. Lung Dysbiosis, Inflammation, and Injury in Hematopoietic Cell Transplantation. American Journal of Respiratory and Critical Care Medicine. PMID 29878854 DOI: 10.1164/rccm.201712-2456OC  1
2018 Dickson RP, Erb-Downward JR, Falkowski NR, Hunter EM, Ashley SL, Huffnagle GB. The Lung Microbiota of Healthy Mice are Highly Variable, Cluster by Environment, and Reflect Variation in Baseline Lung Innate Immunity. American Journal of Respiratory and Critical Care Medicine. PMID 29533677 DOI: 10.1164/rccm.201711-2180OC  1
2018 Scales BS, Erb-Downward JR, Falkowski NR, LiPuma JJ, Huffnagle GB. Genome Sequences of 12Strains Isolated from the Lungs of Humans. Genome Announcements. 6. PMID 29449399 DOI: 10.1128/genomeA.01461-17  1
2017 Singer BH, Dickson RP, Denstaedt SJ, Newstead MW, Kim K, Falkowski NR, Erb-Downward JR, Schmidt TM, Huffnagle GB, Standiford TJ. Bacterial Dissemination to the Brain in Sepsis. American Journal of Respiratory and Critical Care Medicine. PMID 29232157 DOI: 10.1164/rccm.201708-1559OC  1
2017 Pendleton KM, Erb-Downward JR, Bao Y, Branton WR, Falkowski NR, Newton DW, Huffnagle GB, Dickson RP. Reply to Clinical Metagenomics for the Diagnostic of Hospital-acquired Infections: Promises and Hurdles. American Journal of Respiratory and Critical Care Medicine. PMID 28679063 DOI: 10.1164/rccm.201706-1144LE  1
2017 Pendleton KM, Erb-Downward JR, Bao Y, Branton WR, Falkowski NR, Newton DW, Huffnagle GB, Dickson RP. Rapid Pathogen Identification in Bacterial Pneumonia Using Real-time Metagenomics. American Journal of Respiratory and Critical Care Medicine. PMID 28475350 DOI: 10.1164/rccm.201703-0537LE  1
2017 Pendleton KM, Huffnagle GB, Dickson RP. The significance of Candida in the human respiratory tract: our evolving understanding. Pathogens and Disease. 75. PMID 28423168 DOI: 10.1093/femspd/ftx029  0.72
2017 Dickson RP, Erb-Downward JR, Freeman CM, McCloskey L, Falkowski NR, Huffnagle GB, Curtis JL. Bacterial Topography of the Healthy Human Lower Respiratory Tract. Mbio. 8. PMID 28196961 DOI: 10.1128/mBio.02287-16  1
2017 Huang Y, Ma SF, Espindola MS, Vij R, Oldham JM, Huffnagle GB, Erb-Downward JR, Flaherty KR, Moore BB, White ES, Zhou T, Li J, Lussier YA, Han MK, Kaminski N, et al. Microbes Associate with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 28157391 DOI: 10.1164/rccm.201607-1525OC  1
2016 McDermott AJ, Falkowski NR, McDonald RA, Frank CR, Pandit CR, Young VB, Huffnagle GB. Role of Gamma-Interferon and Inflammatory Monocytes in Driving Colonic Inflammation During Acute C. difficile Infection in Mice. Immunology. PMID 27995603 DOI: 10.1111/imm.12700  0.92
2016 Kitsios GD, Morowitz MJ, Dickson RP, Huffnagle GB, McVerry BJ, Morris A. Dysbiosis in the intensive care unit: Microbiome science coming to the bedside. Journal of Critical Care. 38: 84-91. PMID 27866110 DOI: 10.1016/j.jcrc.2016.09.029  0.72
2016 Dickson RP, Singer BH, Newstead MW, Falkowski NR, Erb-Downward JR, Standiford TJ, Huffnagle GB. Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome. Nature Microbiology. 1: 16113. PMID 27670109 DOI: 10.1038/nmicrobiol.2016.113  1
2016 Huang YJ, Erb-Downward JR, Dickson R, Curtis JL, Huffnagle GB, Han MK. Understanding the role of the microbiome in chronic obstructive pulmonary disease: principles, challenges, and future directions. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 27392936 DOI: 10.1016/j.trsl.2016.06.007  1
2016 Scales BS, Dickson RP, Huffnagle GB. A tale of two sites: how inflammation can reshape the microbiomes of the gut and lungs. Journal of Leukocyte Biology. PMID 27365534 DOI: 10.1189/jlb.3MR0316-106R  0.72
2016 Adar SD, Huffnagle GB, Curtis JL. The respiratory microbiome: an underappreciated player in the human response to inhaled pollutants? Annals of Epidemiology. PMID 27161078 DOI: 10.1016/j.annepidem.2016.03.010  1
2016 Dickson RP, Erb-Downward JR, Martinez FJ, Huffnagle GB. The Microbiome and the Respiratory Tract. Annual Review of Physiology. 78: 481-504. PMID 26527186 DOI: 10.1146/annurev-physiol-021115-105238  1
2015 Scales BS, Erb-Downward JR, Huffnagle IM, LiPuma JJ, Huffnagle GB. Comparative genomics of Pseudomonas fluorescens subclade III strains from human lungs. Bmc Genomics. 16: 1032. PMID 26644001 DOI: 10.1186/s12864-015-2261-2  1
2015 McDermott AJ, Falkowski NR, McDonald RA, Pandit CR, Young VB, Huffnagle GB. IL-23, Independent of IL-17 and IL-22, Drives Neutrophil Recruitment and Innate Inflammation During Clostridium difficile Colitis in Mice. Immunology. PMID 26455347 DOI: 10.1111/imm.12545  1
2015 Dickson RP, Erb-Downward JR, Huffnagle GB. Homeostasis and its disruption in the lung microbiome. American Journal of Physiology. Lung Cellular and Molecular Physiology. 309: L1047-55. PMID 26432870 DOI: 10.1152/ajplung.00279.2015  1
2015 Curtis JL, Freeman CM, Huffnagle GB. "B" for Bad, Beneficial, or Both? Lung Lymphoid Neogenesis in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 192: 648-51. PMID 26371807 DOI: 10.1164/rccm.201506-1230ED  1
2015 Scales BS, Erb-Downward JR, LiPuma JJ, Huffnagle GB. Draft Genome Sequences of Five Pseudomonas fluorescens Subclade I and II Strains, Isolated from Human Respiratory Samples. Genome Announcements. 3. PMID 26227600 DOI: 10.1128/genomeA.00837-15  1
2015 Dickson RP, Erb-Downward JR, Prescott HC, Martinez FJ, Curtis JL, Lama VN, Huffnagle GB. Intraalveolar Catecholamines and the Human Lung Microbiome. American Journal of Respiratory and Critical Care Medicine. 192: 257-9. PMID 26177175 DOI: 10.1164/rccm.201502-0326LE  1
2015 Dickson RP, Huffnagle GB. The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease. Plos Pathogens. 11: e1004923. PMID 26158874 DOI: 10.1371/journal.ppat.1004923  1
2015 Huffnagle GB, Dickson RP. The bacterial microbiota in inflammatory lung diseases. Clinical Immunology (Orlando, Fla.). 159: 177-82. PMID 26122174 DOI: 10.1016/j.clim.2015.05.022  1
2015 Sze MA, Dimitriu PA, Suzuki M, McDonough JE, Campbell JD, Brothers JF, Erb-Downward JR, Huffnagle GB, Hayashi S, Elliott WM, Cooper J, Sin DD, Lenburg ME, Spira A, Mohn WW, et al. The Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 25945594 DOI: 10.1164/rccm.201502-0223OC  1
2015 Dickson RP, Erb-Downward JR, Freeman CM, McCloskey L, Beck JM, Huffnagle GB, Curtis JL. Spatial Variation in the Healthy Human Lung Microbiome and the Adapted Island Model of Lung Biogeography. Annals of the American Thoracic Society. 12: 821-30. PMID 25803243 DOI: 10.1513/AnnalsATS.201501-029OC  1
2015 Bassis CM, Erb-Downward JR, Dickson RP, Freeman CM, Schmidt TM, Young VB, Beck JM, Curtis JL, Huffnagle GB. Analysis of the upper respiratory tract microbiotas as the source of the lung and gastric microbiotas in healthy individuals. Mbio. 6: e00037. PMID 25736890 DOI: 10.1128/mBio.00037-15  1
2015 Scales BS, Erb-Downward JR, Huffnagle IM, LiPuma JJ, Huffnagle GB. Draft Genome Sequences of Seven Pseudomonas fluorescens Subclade III Strains Isolated from Cystic Fibrosis Patients. Genome Announcements. 3. PMID 25635025 DOI: 10.1128/genomeA.01285-14  1
2015 Venkataraman A, Bassis CM, Beck JM, Young VB, Curtis JL, Huffnagle GB, Schmidt TM. Application of a neutral community model to assess structuring of the human lung microbiome. Mbio. 6. PMID 25604788 DOI: 10.1128/mBio.02284-14  1
2015 McDermott AJ, Higdon KE, Muraglia R, Erb-Downward JR, Falkowski NR, McDonald RA, Young VB, Huffnagle GB. The role of Gr-1(+) cells and tumour necrosis factor-α signalling during Clostridium difficile colitis in mice. Immunology. 144: 704-16. PMID 25399934 DOI: 10.1111/imm.12425  1
2015 Sadighi Akha AA, McDermott AJ, Theriot CM, Carlson PE, Frank CR, McDonald RA, Falkowski NR, Bergin IL, Young VB, Huffnagle GB. Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice. Immunology. 144: 587-97. PMID 25327211 DOI: 10.1111/imm.12414  0.92
2014 Wang J, Shen N, Du Y, Erb-Downward JR, Huffnagle GB, Gyetko MR, He B. [Preparation of metagenomic DNA from bronchoalveolar lavage fluids of patients with chronic obstructive pulmonary diseases]. Wei Sheng Wu Xue Bao = Acta Microbiologica Sinica. 54: 943-9. PMID 25345027  1
2014 Scales BS, Dickson RP, LiPuma JJ, Huffnagle GB. Microbiology, genomics, and clinical significance of the Pseudomonas fluorescens species complex, an unappreciated colonizer of humans. Clinical Microbiology Reviews. 27: 927-48. PMID 25278578 DOI: 10.1128/CMR.00044-14  1
2014 Dickson RP, Erb-Downward JR, Prescott HC, Martinez FJ, Curtis JL, Lama VN, Huffnagle GB. Cell-associated bacteria in the human lung microbiome. Microbiome. 2: 28. PMID 25206976 DOI: 10.1186/2049-2618-2-28  1
2014 Dickson RP, Martinez FJ, Huffnagle GB. The role of the microbiome in exacerbations of chronic lung diseases. Lancet (London, England). 384: 691-702. PMID 25152271 DOI: 10.1016/S0140-6736(14)61136-3  1
2014 Dickson RP, Erb-Downward JR, Prescott HC, Martinez FJ, Curtis JL, Lama VN, Huffnagle GB. Analysis of culture-dependent versus culture-independent techniques for identification of bacteria in clinically obtained bronchoalveolar lavage fluid. Journal of Clinical Microbiology. 52: 3605-13. PMID 25078910 DOI: 10.1128/JCM.01028-14  1
2014 McDermott AJ, Frank CR, Falkowski NR, McDonald RA, Young VB, Huffnagle GB. Role of GM-CSF in the inflammatory cytokine network that regulates neutrophil influx into the colonic mucosa during Clostridium difficile infection in mice. Gut Microbes. 5: 476-84. PMID 25045999 DOI: 10.4161/gmic.29964  1
2014 El-Zaatari M, Chang YM, Zhang M, Franz M, Shreiner A, McDermott AJ, van der Sluijs KF, Lutter R, Grasberger H, Kamada N, Young VB, Huffnagle GB, Kao JY. Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology. Journal of Immunology (Baltimore, Md. : 1950). 193: 807-16. PMID 24935925 DOI: 10.4049/jimmunol.1302913  1
2014 Dickson RP, Erb-Downward JR, Freeman CM, Walker N, Scales BS, Beck JM, Martinez FJ, Curtis JL, Lama VN, Huffnagle GB. Changes in the lung microbiome following lung transplantation include the emergence of two distinct Pseudomonas species with distinct clinical associations. Plos One. 9: e97214. PMID 24831685 DOI: 10.1371/journal.pone.0097214  1
2014 Han MK, Zhou Y, Murray S, Tayob N, Noth I, Lama VN, Moore BB, White ES, Flaherty KR, Huffnagle GB, Martinez FJ. Lung microbiome and disease progression in idiopathic pulmonary fibrosis: an analysis of the COMET study. The Lancet. Respiratory Medicine. 2: 548-56. PMID 24767767 DOI: 10.1016/S2213-2600(14)70069-4  1
2014 Camargo CA, Budinger GR, Escobar GJ, Hansel NN, Hanson CK, Huffnagle GB, Buist AS. Promotion of lung health: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases. Annals of the American Thoracic Society. 11: S125-38. PMID 24754821 DOI: 10.1513/AnnalsATS.201312-451LD  1
2014 Rao K, Erb-Downward JR, Walk ST, Micic D, Falkowski N, Santhosh K, Mogle JA, Ring C, Young VB, Huffnagle GB, Aronoff DM. The systemic inflammatory response to Clostridium difficile infection. Plos One. 9: e92578. PMID 24643077 DOI: 10.1371/journal.pone.0092578  1
2014 Dickson RP, Erb-Downward JR, Huffnagle GB. Towards an ecology of the lung: new conceptual models of pulmonary microbiology and pneumonia pathogenesis. The Lancet. Respiratory Medicine. 2: 238-46. PMID 24621685 DOI: 10.1016/S2213-2600(14)70028-1  1
2014 Huffnagle GB. Increase in dietary fiber dampens allergic responses in the lung. Nature Medicine. 20: 120-1. PMID 24504401 DOI: 10.1038/nm.3472  1
2014 Theriot CM, Koenigsknecht MJ, Carlson PE, Hatton GE, Nelson AM, Li B, Huffnagle GB, Z Li J, Young VB. Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection. Nature Communications. 5: 3114. PMID 24445449 DOI: 10.1038/ncomms4114  1
2014 Marino S, Baxter NT, Huffnagle GB, Petrosino JF, Schloss PD. Mathematical modeling of primary succession of murine intestinal microbiota. Proceedings of the National Academy of Sciences of the United States of America. 111: 439-44. PMID 24367073 DOI: 10.1073/pnas.1311322111  1
2014 McDermott AJ, Huffnagle GB. The microbiome and regulation of mucosal immunity. Immunology. 142: 24-31. PMID 24329495 DOI: 10.1111/imm.12231  1
2014 Murdock BJ, Huffnagle GB, Olszewski MA, Osterholzer JJ. Interleukin-17A enhances host defense against cryptococcal lung infection through effects mediated by leukocyte recruitment, activation, and gamma interferon production. Infection and Immunity. 82: 937-48. PMID 24324191 DOI: 10.1128/IAI.01477-13  1
2014 Ravel J, Blaser MJ, Braun J, Brown E, Bushman FD, Chang EB, Davies J, Dewey KG, Dinan T, Dominguez-Bello M, Erdman SE, Finlay BB, Garrett WS, Huffnagle GB, Huttenhower C, et al. Human microbiome science: Vision for the future, Bethesda, MD, July 24 to 26, 2013 Microbiome. 2.  1
2013 Vital M, Penton CR, Wang Q, Young VB, Antonopoulos DA, Sogin ML, Morrison HG, Raffals L, Chang EB, Huffnagle GB, Schmidt TM, Cole JR, Tiedje JM. A gene-targeted approach to investigate the intestinal butyrate-producing bacterial community. Microbiome. 1: 8. PMID 24451334 DOI: 10.1186/2049-2618-1-8  1
2013 Nagalingam NA, Robinson CJ, Bergin IL, Eaton KA, Huffnagle GB, Young VB. The effects of intestinal microbial community structure on disease manifestation in IL-10-/- mice infected with Helicobacter hepaticus. Microbiome. 1: 15. PMID 24450737 DOI: 10.1186/2049-2618-1-15  1
2013 Twigg HL, Morris A, Ghedin E, Curtis JL, Huffnagle GB, Crothers K, Campbell TB, Flores SC, Fontenot AP, Beck JM, Huang L, Lynch S, Knox KS, Weinstock G. Use of bronchoalveolar lavage to assess the respiratory microbiome: signal in the noise. The Lancet. Respiratory Medicine. 1: 354-6. PMID 24429191 DOI: 10.1016/S2213-2600(13)70117-6  1
2013 Martinez FJ, Erb-Downward JR, Huffnagle GB. Significance of the microbiome in chronic obstructive pulmonary disease. Annals of the American Thoracic Society. 10: S170-9. PMID 24313769 DOI: 10.1513/AnnalsATS.201306-204AW  1
2013 Dickson RP, Huang YJ, Martinez FJ, Huffnagle GB. The lung microbiome and viral-induced exacerbations of chronic obstructive pulmonary disease: new observations, novel approaches. American Journal of Respiratory and Critical Care Medicine. 188: 1185-6. PMID 24236585 DOI: 10.1164/rccm.201309-1573ED  1
2013 Erb Downward JR, Falkowski NR, Mason KL, Muraglia R, Huffnagle GB. Modulation of post-antibiotic bacterial community reassembly and host response by Candida albicans. Scientific Reports. 3: 2191. PMID 23846617 DOI: 10.1038/srep02191  1
2013 Davis MJ, Tsang TM, Qiu Y, Dayrit JK, Freij JB, Huffnagle GB, Olszewski MA. Macrophage M1/M2 polarization dynamically adapts to changes in cytokine microenvironments in Cryptococcus neoformans infection. Mbio. 4: e00264-13. PMID 23781069 DOI: 10.1128/mBio.00264-13  1
2013 Dickson RP, Erb-Downward JR, Huffnagle GB. The role of the bacterial microbiome in lung disease. Expert Review of Respiratory Medicine. 7: 245-57. PMID 23734647 DOI: 10.1586/ers.13.24  1
2013 Huffnagle GB, Noverr MC. The emerging world of the fungal microbiome. Trends in Microbiology. 21: 334-41. PMID 23685069 DOI: 10.1016/j.tim.2013.04.002  1
2013 Sadighi Akha AA, Theriot CM, Erb-Downward JR, McDermott AJ, Falkowski NR, Tyra HM, Rutkowski DT, Young VB, Huffnagle GB. Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response. Immunology. 140: 111-22. PMID 23668260 DOI: 10.1111/imm.12122  1
2013 Miyasaka EA, Feng Y, Poroyko V, Falkowski NR, Erb-Downward J, Gillilland MG, Mason KL, Huffnagle GB, Teitelbaum DH. Total parenteral nutrition-associated lamina propria inflammation in mice is mediated by a MyD88-dependent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 190: 6607-15. PMID 23667106 DOI: 10.4049/jimmunol.1201746  1
2013 Rao K, Walk ST, Micic D, Chenoweth E, Deng L, Galecki AT, Jain R, Trivedi I, Yu M, Santhosh K, Ring C, Young VB, Huffnagle GB, Aronoff DM. Procalcitonin levels associate with severity of Clostridium difficile infection. Plos One. 8: e58265. PMID 23505476 DOI: 10.1371/journal.pone.0058265  1
2013 Sun Y, Zhang M, Chen CC, Gillilland M, Sun X, El-Zaatari M, Huffnagle GB, Young VB, Zhang J, Hong SC, Chang YM, Gumucio DL, Owyang C, Kao JY. Stress-induced corticotropin-releasing hormone-mediated NLRP6 inflammasome inhibition and transmissible enteritis in mice. Gastroenterology. 144: 1478-87, 1487.e1-8. PMID 23470617 DOI: 10.1053/j.gastro.2013.02.038  1
2013 Scales BS, Huffnagle GB. The microbiome in wound repair and tissue fibrosis. The Journal of Pathology. 229: 323-31. PMID 23042513 DOI: 10.1002/path.4118  1
2012 Erb-Downward JR, Sadighi Akha AA, Wang J, Shen N, He B, Martinez FJ, Gyetko MR, Curtis JL, Huffnagle GB. Use of direct gradient analysis to uncover biological hypotheses in 16s survey data and beyond. Scientific Reports. 2: 774. PMID 23336065 DOI: 10.1038/srep00774  1
2012 Berndt BE, Zhang M, Owyang SY, Cole TS, Wang TW, Luther J, Veniaminova NA, Merchant JL, Chen CC, Huffnagle GB, Kao JY. Butyrate increases IL-23 production by stimulated dendritic cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G1384-92. PMID 23086919 DOI: 10.1152/ajpgi.00540.2011  1
2012 Mason KL, Erb Downward JR, Mason KD, Falkowski NR, Eaton KA, Kao JY, Young VB, Huffnagle GB. Candida albicans and bacterial microbiota interactions in the cecum during recolonization following broad-spectrum antibiotic therapy. Infection and Immunity. 80: 3371-80. PMID 22778094 DOI: 10.1128/IAI.00449-12  0.96
2012 Beck JM, Young VB, Huffnagle GB. The microbiome of the lung. Translational Research : the Journal of Laboratory and Clinical Medicine. 160: 258-66. PMID 22683412 DOI: 10.1016/j.trsl.2012.02.005  1
2012 Erb-Downward JR, Huffnagle GB, Martinez FJ. The microbiota in respiratory disease. American Journal of Respiratory and Critical Care Medicine. 185: 1037-8. PMID 22589308 DOI: 10.1164/rccm.201203-0567ED  1
2012 Han MK, Huang YJ, Lipuma JJ, Boushey HA, Boucher RC, Cookson WO, Curtis JL, Erb-Downward J, Lynch SV, Sethi S, Toews GB, Young VB, Wolfgang MC, Huffnagle GB, Martinez FJ. Significance of the microbiome in obstructive lung disease. Thorax. 67: 456-63. PMID 22318161 DOI: 10.1136/thoraxjnl-2011-201183  1
2012 Gillilland MG, Erb-Downward JR, Bassis CM, Shen MC, Toews GB, Young VB, Huffnagle GB. Ecological succession of bacterial communities during conventionalization of germ-free mice. Applied and Environmental Microbiology. 78: 2359-66. PMID 22286988 DOI: 10.1128/AEM.05239-11  1
2012 Murdock BJ, Falkowski NR, Shreiner AB, Sadighi Akha AA, McDonald RA, White ES, Toews GB, Huffnagle GB. Interleukin-17 drives pulmonary eosinophilia following repeated exposure to Aspergillus fumigatus conidia. Infection and Immunity. 80: 1424-36. PMID 22252873 DOI: 10.1128/IAI.05529-11  1
2012 Shreiner AB, Murdock BJ, Sadighi Akha AA, Falkowski NR, Christensen PJ, White ES, Hogaboam CM, Huffnagle GB. Repeated exposure to Aspergillus fumigatus conidia results in CD4+ T cell-dependent and -independent pulmonary arterial remodeling in a mixed Th1/Th2/Th17 microenvironment that requires interleukin-4 (IL-4) and IL-10. Infection and Immunity. 80: 388-97. PMID 22064716 DOI: 10.1128/IAI.05530-11  1
2012 Mason KL, Erb Downward JR, Falkowski NR, Young VB, Kao JY, Huffnagle GB. Interplay between the gastric bacterial microbiota and Candida albicans during postantibiotic recolonization and gastritis. Infection and Immunity. 80: 150-8. PMID 21986629 DOI: 10.1128/IAI.05162-11  1
2012 Gillilland MG, Young VB, Huffnagle GB. Gastrointestinal Microbial Ecology with Perspectives on Health and Disease Physiology of the Gastrointestinal Tract. 1: 1119-1134. DOI: 10.1016/B978-0-12-382026-6.00040-3  1
2011 Reeves AE, Theriot CM, Bergin IL, Huffnagle GB, Schloss PD, Young VB. The interplay between microbiome dynamics and pathogen dynamics in a murine model of Clostridium difficile Infection. Gut Microbes. 2: 145-58. PMID 21804357 DOI: 10.4161/gmic.2.3.16333  1
2011 Arora S, Olszewski MA, Tsang TM, McDonald RA, Toews GB, Huffnagle GB. Effect of cytokine interplay on macrophage polarization during chronic pulmonary infection with Cryptococcus neoformans. Infection and Immunity. 79: 1915-26. PMID 21383052 DOI: 10.1128/IAI.01270-10  1
2011 Erb-Downward JR, Thompson DL, Han MK, Freeman CM, McCloskey L, Schmidt LA, Young VB, Toews GB, Curtis JL, Sundaram B, Martinez FJ, Huffnagle GB. Analysis of the lung microbiome in the "healthy" smoker and in COPD. Plos One. 6: e16384. PMID 21364979 DOI: 10.1371/journal.pone.0016384  1
2011 Osterholzer JJ, Chen GH, Olszewski MA, Zhang YM, Curtis JL, Huffnagle GB, Toews GB. Chemokine receptor 2-mediated accumulation of fungicidal exudate macrophages in mice that clear cryptococcal lung infection. The American Journal of Pathology. 178: 198-211. PMID 21224057 DOI: 10.1016/j.ajpath.2010.11.006  1
2011 Murdock BJ, Shreiner AB, McDonald RA, Osterholzer JJ, White ES, Toews GB, Huffnagle GB. Coevolution of TH1, TH2, and TH17 responses during repeated pulmonary exposure to Aspergillus fumigatus conidia. Infection and Immunity. 79: 125-35. PMID 21041495 DOI: 10.1128/IAI.00508-10  1
2010 Reid G, Gaudier E, Guarner F, Huffnagle GB, Macklaim JM, Munoz AM, Martini M, Ringel-Kulka T, Sartor B, Unal R, Verbeke K, Walter J. Responders and non-responders to probiotic interventions: how can we improve the odds? Gut Microbes. 1: 200-4. PMID 21637034 DOI: 10.4161/gmic.1.3.12013  1
2010 Chen GH, Osterholzer JJ, Choe MY, McDonald RA, Olszewski MA, Huffnagle GB, Toews GB. Dual roles of CD40 on microbial containment and the development of immunopathology in response to persistent fungal infection in the lung. The American Journal of Pathology. 177: 2459-71. PMID 20864680 DOI: 10.2353/ajpath.2010.100141  1
2010 Olszewski MA, Zhang Y, Huffnagle GB. Mechanisms of cryptococcal virulence and persistence. Future Microbiology. 5: 1269-88. PMID 20722603 DOI: 10.2217/fmb.10.93  1
2010 Zhang Y, Wang F, Bhan U, Huffnagle GB, Toews GB, Standiford TJ, Olszewski MA. TLR9 signaling is required for generation of the adaptive immune protection in Cryptococcus neoformans-infected lungs. The American Journal of Pathology. 177: 754-65. PMID 20581055 DOI: 10.2353/ajpath.2010.091104  1
2010 Huffnagle GB. The microbiota and allergies/asthma. Plos Pathogens. 6: e1000549. PMID 20523892 DOI: 10.1371/journal.ppat.1000549  1
2010 Shetron-Rama LM, Herring-Palmer AC, Huffnagle GB, Hanna P. Transport of Bacillus anthracis from the lungs to the draining lymph nodes is a rapid process facilitated by CD11c+ cells. Microbial Pathogenesis. 49: 38-46. PMID 20188814 DOI: 10.1016/j.micpath.2010.02.004  1
2010 Milam JE, Erb-Downward JR, Chen GH, Osuchowski MF, McDonald R, Chensue SW, Toews GB, Huffnagle GB, Olszewski MA. CD11c+ cells are required to prevent progression from local acute lung injury to multiple organ failure and death American Journal of Pathology. 176: 218-226. PMID 19948830 DOI: 10.2353/ajpath.2010.081027  1
2009 Osterholzer JJ, Chen GH, Olszewski MA, Curtis JL, Huffnagle GB, Toews GB. Accumulation of CD11b+ lung dendritic cells in response to fungal infection results from the CCR2-mediated recruitment and differentiation of Ly-6Chigh monocytes. Journal of Immunology (Baltimore, Md. : 1950). 183: 8044-53. PMID 19933856 DOI: 10.4049/jimmunol.0902823  1
2009 Zhang Y, Wang F, Tompkins KC, McNamara A, Jain AV, Moore BB, Toews GB, Huffnagle GB, Olszewski MA. Robust Th1 and Th17 immunity supports pulmonary clearance but cannot prevent systemic dissemination of highly virulent Cryptococcus neoformans H99. The American Journal of Pathology. 175: 2489-500. PMID 19893050 DOI: 10.2353/ajpath.2009.090530  1
2009 Jain AV, Zhang Y, Fields WB, McNamara DA, Choe MY, Chen GH, Erb-Downward J, Osterholzer JJ, Toews GB, Huffnagle GB, Olszewski MA. Th2 but not Th1 immune bias results in altered lung functions in a murine model of pulmonary Cryptococcus neoformans infection. Infection and Immunity. 77: 5389-99. PMID 19752036 DOI: 10.1128/IAI.00809-09  1
2009 Osterholzer JJ, Milam JE, Chen GH, Toews GB, Huffnagle GB, Olszewski MA. Role of dendritic cells and alveolar macrophages in regulating early host defense against pulmonary infection with Cryptococcus neoformans Infection and Immunity. 77: 3749-3755. PMID 19564388 DOI: 10.1128/IAI.00454-09  1
2009 Mason KL, Huffnagle GB. Control of mucosal polymicrobial populations by innate immunity. Cellular Microbiology. 11: 1297-305. PMID 19558617 DOI: 10.1111/j.1462-5822.2009.01347.x  1
2009 Goldman DL, Huffnagle GB. Potential contribution of fungal infection and colonization to the development of allergy. Medical Mycology. 47: 445-56. PMID 19384753 DOI: 10.1080/13693780802641904  1
2009 Osterholzer JJ, Surana R, Milam JE, Montano GT, Chen GH, Sonstein J, Curtis JL, Huffnagle GB, Toews GB, Olszewskiz MA. Cryptococcal urease promotes the accumulation of immature dendritic cells and a non-protective T2 immune response within the lung American Journal of Pathology. 174: 932-943. PMID 19218345 DOI: 10.2353/ajpath.2009.080673  1
2009 O'Malley HA, Shreiner AB, Chen GH, Huffnagle GB, Isom LL. Loss of Na+ channel beta2 subunits is neuroprotective in a mouse model of multiple sclerosis. Molecular and Cellular Neurosciences. 40: 143-55. PMID 19013247 DOI: 10.1016/j.mcn.2008.10.001  1
2008 Shreiner A, Huffnagle GB, Noverr MC. The "Microflora Hypothesis" of allergic disease. Advances in Experimental Medicine and Biology. 635: 113-34. PMID 18841708 DOI: 10.1007/978-0-387-09550-9_10  1
2008 Mason KL, Huffnagle GB, Noverr MC, Kao JY. Overview of gut immunology. Advances in Experimental Medicine and Biology. 635: 1-14. PMID 18841699 DOI: 10.1007/978-0-387-09550-9_1  1
2008 Lau HY, Huffnagle GB, Moore TA. Host and microbiota factors that control Klebsiella pneumoniae mucosal colonization in mice. Microbes and Infection / Institut Pasteur. 10: 1283-90. PMID 18762269 DOI: 10.1016/j.micinf.2008.07.040  1
2008 Osterholzer JJ, Curtis JL, Polak T, Ames T, Chen GH, McDonald R, Huffnagle GB, Toews GB. CCR2 mediates conventional dendritic cell recruitment and the formation of bronchovascular mononuclear cell infiltrates in the lungs of mice infected with Cryptococcus neoformans. Journal of Immunology (Baltimore, Md. : 1950). 181: 610-20. PMID 18566428  1
2008 Erb-Downward JR, Noggle RM, Williamson PR, Huffnagle GB. The role of laccase in prostaglandin production by Cryptococcus neoformans. Molecular Microbiology. 68: 1428-37. PMID 18410494 DOI: 10.1111/j.1365-2958.2008.06245.x  1
2008 Chen GH, McNamara DA, Hernandez Y, Huffnagle GB, Toews GB, Olszewski MA. Inheritance of immune polarization patterns is linked to resistance versus susceptibility to Cryptococcus neoformans in a mouse model. Infection and Immunity. 76: 2379-91. PMID 18391002 DOI: 10.1128/IAI.01143-07  1
2007 Berndt BE, Zhang M, Chen GH, Huffnagle GB, Kao JY. The role of dendritic cells in the development of acute dextran sulfate sodium colitis. Journal of Immunology (Baltimore, Md. : 1950). 179: 6255-62. PMID 17947701  1
2007 Rodriguez TE, Falkowski NR, Harkema JR, Huffnagle GB. Role of neutrophils in preventing and resolving acute fungal sinusitis. Infection and Immunity. 75: 5663-8. PMID 17875637 DOI: 10.1128/IAI.01542-06  1
2007 Olszewski MA, Falkowski NR, Surana R, Sonstein J, Hartman A, Moore BB, Huffnagle GB, Toews GB. Effect of laparotomy on clearance and cytokine induction in Staphylococcus aureus infected lungs. American Journal of Respiratory and Critical Care Medicine. 176: 921-9. PMID 17702970 DOI: 10.1164/rccm.200606-763OC  1
2007 Milam JE, Herring-Palmer AC, Pandrangi R, McDonald RA, Huffnagle GB, Toews GB. Modulation of the pulmonary type 2 T-cell response to Cryptococcus neoformans by intratracheal delivery of a tumor necrosis factor alpha-expressing adenoviral vector Infection and Immunity. 75: 4951-4958. PMID 17646355 DOI: 10.1128/IAI.00176-07  1
2007 Chen GH, Olszewski MA, McDonald RA, Wells JC, Paine R, Huffnagle GB, Toews GB. Role of granulocyte macrophage colony-stimulating factor in host defense against pulmonary Cryptococcus neoformans infection during murine allergic bronchopulmonary mycosis. The American Journal of Pathology. 170: 1028-40. PMID 17322386 DOI: 10.2353/ajpath.2007.060595  1
2007 Erb-Downward JR, Huffnagle GB. Cryptococcus neoformans produces authentic prostaglandin E2 without a cyclooxygenase. Eukaryotic Cell. 6: 346-50. PMID 17158733 DOI: 10.1128/EC.00336-06  1
2006 Erb-Downward JR, Huffnagle GB. Role of oxylipins and other lipid mediators in fungal pathogenesis. Future Microbiology. 1: 219-27. PMID 17661667 DOI: 10.2217/17460913.1.2.219  1
2006 Lindell DM, Ballinger MN, McDonald RA, Toews GB, Huffnagle GB. Immunologic homeostasis during infection: coexistence of strong pulmonary cell-mediated immunity to secondary Cryptococcus neoformans infection while the primary infection still persists at low levels in the lungs. Journal of Immunology (Baltimore, Md. : 1950). 177: 4652-61. PMID 16982904  1
2006 Lindell DM, Ballinger MN, McDonald RA, Toews GB, Huffnagle GB. Diversity of the T-cell response to pulmonary Cryptococcus neoformans infection. Infection and Immunity. 74: 4538-48. PMID 16861640 DOI: 10.1128/IAI.00080-06  1
2006 Arora S, McDonald RA, Toews GB, Huffnagle GB. Effect of a CD4-depleting antibody on the development of Cryptococcus neoformans-induced allergic bronchopulmonary mycosis in mice. Infection and Immunity. 74: 4339-48. PMID 16790808 DOI: 10.1128/IAI.01989-05  1
2006 Heffernan BJ, Thomason B, Herring-Palmer A, Shaughnessy L, McDonald R, Fisher N, Huffnagle GB, Hanna P. Bacillus anthracis phospholipases C facilitate macrophage-associated growth and contribute to virulence in a murine model of inhalation anthrax. Infection and Immunity. 74: 3756-64. PMID 16790747 DOI: 10.1128/IAI.00307-06  1
2006 Lindell DM, Moore TA, McDonald RA, Toews GB, Huffnagle GB. Distinct compartmentalization of CD4+ T-cell effector function versus proliferative capacity during pulmonary cryptococcosis. The American Journal of Pathology. 168: 847-55. PMID 16507900 DOI: 10.2353/ajpath.2006.050522  1
2006 Mancuso P, Huffnagle GB, Olszewski MA, Phipps J, Peters-Golden M. Leptin corrects host defense defects after acute starvation in murine pneumococcal pneumonia. American Journal of Respiratory and Critical Care Medicine. 173: 212-8. PMID 16210671 DOI: 10.1164/rccm.200506-909OC  1
2005 Noverr MC, Huffnagle GB. The 'microflora hypothesis' of allergic diseases. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 35: 1511-20. PMID 16393316 DOI: 10.1111/j.1365-2222.2005.02379.x  1
2005 Amlie-Lefond C, Paz DA, Connelly MP, Huffnagle GB, Dunn KS, Whelan NT, Whelan HT. Innate immunity for biodefense: a strategy whose time has come. The Journal of Allergy and Clinical Immunology. 116: 1334-42. PMID 16337468 DOI: 10.1016/j.jaci.2005.08.048  1
2005 Arora S, Huffnagle GB. Immune regulation during allergic bronchopulmonary mycosis: lessons taught by two fungi. Immunologic Research. 33: 53-68. PMID 16120972 DOI: 10.1385/IR:33:1:053  1
2005 Schaller MA, Lundy SK, Huffnagle GB, Lukacs NW. CD8+ T cell contributions to allergen induced pulmonary inflammation and airway hyperreactivity. European Journal of Immunology. 35: 2061-70. PMID 15948214 DOI: 10.1002/eji.200425715  1
2005 Lindell DM, Moore TA, McDonald RA, Toews GB, Huffnagle GB. Generation of antifungal effector CD8+ T cells in the absence of CD4+ T cells during Cryptococcus neoformans infection. Journal of Immunology (Baltimore, Md. : 1950). 174: 7920-8. PMID 15944298  1
2005 Arora S, Hernandez Y, Erb-Downward JR, McDonald RA, Toews GB, Huffnagle GB. Role of IFN-gamma in regulating T2 immunity and the development of alternatively activated macrophages during allergic bronchopulmonary mycosis. Journal of Immunology (Baltimore, Md. : 1950). 174: 6346-56. PMID 15879135  1
2005 Chen GH, McDonald RA, Wells JC, Huffnagle GB, Lukacs NW, Toews GB. The gamma interferon receptor is required for the protective pulmonary inflammatory response to Cryptococcus neoformans. Infection and Immunity. 73: 1788-96. PMID 15731080 DOI: 10.1128/IAI.73.3.1788-1796.2005  1
2005 Hernandez Y, Arora S, Erb-Downward JR, McDonald RA, Toews GB, Huffnagle GB. Distinct roles for IL-4 and IL-10 in regulating T2 immunity during allergic bronchopulmonary mycosis. Journal of Immunology (Baltimore, Md. : 1950). 174: 1027-36. PMID 15634927  1
2005 Herring AC, Falkowski NR, Chen GH, McDonald RA, Toews GB, Huffnagle GB. Transient neutralization of tumor necrosis factor alpha can produce a chronic fungal infection in an immunocompetent host: potential role of immature dendritic cells. Infection and Immunity. 73: 39-49. PMID 15618139 DOI: 10.1128/IAI.73.1.39-49.2005  1
2005 Noverr MC, Falkowski NR, McDonald RA, McKenzie AN, Huffnagle GB. Development of allergic airway disease in mice following antibiotic therapy and fungal microbiota increase: role of host genetics, antigen, and interleukin-13. Infection and Immunity. 73: 30-8. PMID 15618138 DOI: 10.1128/IAI.73.1.30-38.2005  1
2004 Hernández Y, Herring AC, Huffnagle GB. Pulmonary defenses against fungi. Seminars in Respiratory and Critical Care Medicine. 25: 63-71. PMID 16088450 DOI: 10.1055/s-2004-822306  1
2004 Herring AC, Hernández Y, Huffnagle GB, Toews GB. Role and development of TH1/TH2 immune responses in the lungs. Seminars in Respiratory and Critical Care Medicine. 25: 3-10. PMID 16088444 DOI: 10.1055/s-2004-822300  1
2004 Speyer CL, Gao H, Rancilio NJ, Neff TA, Huffnagle GB, Sarma JV, Ward PA. Novel chemokine responsiveness and mobilization of neutrophils during sepsis. The American Journal of Pathology. 165: 2187-96. PMID 15579460 DOI: 10.1016/S0002-9440(10)63268-3  1
2004 Noverr MC, Huffnagle GB. Does the microbiota regulate immune responses outside the gut? Trends in Microbiology. 12: 562-8. PMID 15539116 DOI: 10.1016/j.tim.2004.10.008  1
2004 Noverr MC, Huffnagle GB. Regulation of Candida albicans morphogenesis by fatty acid metabolites. Infection and Immunity. 72: 6206-10. PMID 15501745 DOI: 10.1128/IAI.72.11.6206-6210.2004  1
2004 Noverr MC, Noggle RM, Toews GB, Huffnagle GB. Role of antibiotics and fungal microbiota in driving pulmonary allergic responses. Infection and Immunity. 72: 4996-5003. PMID 15321991 DOI: 10.1128/IAI.72.9.4996-5003.2004  1
2004 Olszewski MA, Noverr MC, Chen GH, Toews GB, Cox GM, Perfect JR, Huffnagle GB. Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion. The American Journal of Pathology. 164: 1761-71. PMID 15111322 DOI: 10.1016/S0002-9440(10)63734-0  1
2004 Noverr MC, Williamson PR, Fajardo RS, Huffnagle GB. CNLAC1 is required for extrapulmonary dissemination of Cryptococcus neoformans but not pulmonary persistence. Infection and Immunity. 72: 1693-9. PMID 14977977 DOI: 10.1128/IAI.72.3.1693-1699.2004  1
2003 Huffnagle GB, Deepe GS. Innate and adaptive determinants of host susceptibility to medically important fungi. Current Opinion in Microbiology. 6: 344-50. PMID 12941402 DOI: 10.1016/S1369-5274(03)00089-4  1
2003 Noverr MC, Erb-Downward JR, Huffnagle GB. Production of eicosanoids and other oxylipins by pathogenic eukaryotic microbes. Clinical Microbiology Reviews. 16: 517-33. PMID 12857780 DOI: 10.1128/CMR.16.3.517-533.2003  1
2003 Moore SI, Huffnagle GB, Chen GH, White ES, Mancuso P. Leptin modulates neutrophil phagocytosis of Klebsiella pneumoniae. Infection and Immunity. 71: 4182-5. PMID 12819114 DOI: 10.1128/IAI.71.7.4182-4185.2003  1
2003 Noverr MC, Cox GM, Perfect JR, Huffnagle GB. Role of PLB1 in pulmonary inflammation and cryptococcal eicosanoid production. Infection and Immunity. 71: 1538-47. PMID 12595473 DOI: 10.1128/IAI.71.3.1538-1547.2003  1
2003 Bauman SK, Huffnagle GB, Murphy JW. Effects of tumor necrosis factor alpha on dendritic cell accumulation in lymph nodes draining the immunization site and the impact on the anticryptococcal cell-mediated immune response. Infection and Immunity. 71: 68-74. PMID 12496150 DOI: 10.1128/IAI.71.1.68-74.2003  1
2002 Huffnagle GB. Investigating invasive aspergillosis. American Journal of Respiratory and Critical Care Medicine. 166: 1159-60. PMID 12403685 DOI: 10.1164/rccm.2207009  1
2002 Herring AC, Lee J, McDonald RA, Toews GB, Huffnagle GB. Induction of interleukin-12 and gamma interferon requires tumor necrosis factor alpha for protective T1-cell-mediated immunity to pulmonary Cryptococcus neoformans infection. Infection and Immunity. 70: 2959-64. PMID 12010985 DOI: 10.1128/IAI.70.6.2959-2964.2002  1
2002 Traynor TR, Herring AC, Dorf ME, Kuziel WA, Toews GB, Huffnagle GB. Differential roles of CC chemokine ligand 2/monocyte chemotactic protein-1 and CCR2 in the development of T1 immunity. Journal of Immunology (Baltimore, Md. : 1950). 168: 4659-66. PMID 11971015  1
2002 Mancuso P, Gottschalk A, Phare SM, Peters-Golden M, Lukacs NW, Huffnagle GB. Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia. Journal of Immunology (Baltimore, Md. : 1950). 168: 4018-24. PMID 11937559  1
2002 Noverr MC, Toews GB, Huffnagle GB. Production of prostaglandins and leukotrienes by pathogenic fungi. Infection and Immunity. 70: 400-2. PMID 11748207 DOI: 10.1128/IAI.70.1.400-402.2002  1
2001 Lindell DM, Standiford TJ, Mancuso P, Leshen ZJ, Huffnagle GB. Macrophage inflammatory protein 1alpha/CCL3 is required for clearance of an acute Klebsiella pneumoniae pulmonary infection. Infection and Immunity. 69: 6364-9. PMID 11553580 DOI: 10.1128/IAI.69.10.6364-6369.2001  1
2001 Olszewski MA, Huffnagle GB, Traynor TR, McDonald RA, Cook DN, Toews GB. Regulatory effects of macrophage inflammatory protein 1α/CCL3 on the development of immunity to Cryptococcus neoformans depend on expression of early inflammatory cytokines Infection and Immunity. 69: 6256-6263. PMID 11553568 DOI: 10.1128/IAI.69.10.6256-6263.2001  1
2001 Noverr MC, Phare SM, Toews GB, Coffey MJ, Huffnagle GB. Pathogenic yeasts Cryptococcus neoformans and Candida albicans produce immunomodulatory prostaglandins. Infection and Immunity. 69: 2957-63. PMID 11292712 DOI: 10.1128/IAI.69.5.2957-2963.2001  1
2001 Traynor TR, Huffnagle GB. Role of chemokines in fungal infections Medical Mycology. 39: 41-50. PMID 11270407  1
2000 Olszewski MA, Huffnagle GB, McDonald RA, Lindell DM, Moore BB, Cook DN, Toews GB. The role of macrophage inflammatory protein-1 alpha/CCL3 in regulation of T cell-mediated immunity to Cryptococcus neoformans infection. Journal of Immunology (Baltimore, Md. : 1950). 165: 6429-36. PMID 11086082  1
2000 Fife BT, Huffnagle GB, Kuziel WA, Karpus WJ. CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis Journal of Experimental Medicine. 192: 899-905. PMID 10993920 DOI: 10.1084/jem.192.6.899  1
2000 Brieland JK, Engleberg NC, Huffnagle GB, Remick DG, Fantone JC. Host pathogen interactions in Legionnaires' disease: lessons learned from a murine animal model. Immunopharmacology. 48: 249-52. PMID 10960664 DOI: 10.1016/S0162-3109(00)00235-6  1
2000 Huffnagle GB, Traynor TR, McDonald RA, Olszewski MA, Lindell DM, Herring AC, Toews GB. Leukocyte recruitment during pulmonary Cryptococcus neoformans infection. Immunopharmacology. 48: 231-6. PMID 10960662 DOI: 10.1016/S0162-3109(00)00222-8  1
2000 Aliberti J, Reis E Sousa C, Schito M, Hieny S, Wells T, Huffnagle GB, Sher A. CCR5 provides a signal for microbial induced production of IL-12 by CD8α+ dendritic cells Nature Immunology. 1: 83-87. PMID 10881180  1
2000 Traynor TR, Kuziel WA, Toews GB, Huffnagle GB. CCR2 expression determines T1 versus T2 polarization during pulmonary Cryptococcus neoformans infection Journal of Immunology. 164: 2021-2027. PMID 10657654  1
2000 Huffnagle GB, Herring AC, Traynor TR. Role of fungal virulence factors in evasion of host defenses Annual Review of Biomedical Sciences. 2: 77-90. DOI: 10.5016/1806-8774.2000v2p77  1
1999 Coffey MJ, Phare SM, Peters-Golden M, Huffnagle GB. Regulation of 5-lipoxygenase metabolism in mononuclear phagocytes by CD4 T lymphocytes. Experimental Lung Research. 25: 617-29. PMID 10598321 DOI: 10.1080/019021499270051  1
1999 Huffnagle GB, McNeil LK, McDonald RA, Murphy JW, Toews GB, Maeda N, Kuziel WA. Cutting edge: Role of C-C chemokine receptor 5 in organ-specific and innate immunity to Cryptococcus neoformans. Journal of Immunology (Baltimore, Md. : 1950). 163: 4642-6. PMID 10528159  1
1999 Lovchik JA, Wilder JA, Huffnagle GB, Riblet R, Lyons CR, Lipscomb MF. Ig heavy chain complex-linked genes influence the immune response in a murine cryptococcal infection. Journal of Immunology (Baltimore, Md. : 1950). 163: 3907-13. PMID 10490991  1
1999 Huffnagle GB, McNeil LK. Dissemination of C. neoformans to the central nervous system: Role of chemokines, Th1 immunity and leukocyte recruitment Journal of Neurovirology. 5: 76-81. PMID 10190693  1
1998 Huffnagle GB, Lipscomb MF. Cells and cytokines in pulmonary cryptococcosis Research in Immunology. 149: 387-396. PMID 9720956 DOI: 10.1016/S0923-2494(98)80762-1  1
1998 Laichalk LL, Bucknell KA, Huffnagle GB, Wilkowski JM, Moore TA, Romanelli RJ, Standiford TJ. Intrapulmonary delivery of tumor necrosis factor agonist peptide augments host defense in murine gram-negative bacterial pneumonia Infection and Immunity. 66: 2822-2826. PMID 9596755  1
1998 Huffnagle GB, Boyd MB, Street NE, Lipscomb MF. IL-5 is required for eosinophil recruitment, crystal deposition, and mononuclear cell recruitment during a pulmonary Cryptococcus neoformans infection in genetically susceptible mice (C57BL/6) Journal of Immunology. 160: 2393-2400. PMID 9498782  1
1998 Huffnagle GB, Cook DN, McNeil LK, McDonald RM, Toews GB. MIP-1α knockout mice develop a TH2 response following pulmonary Cryptococcus neoformans infection Faseb Journal. 12: A1060.  1
1997 Hogaboam CM, Chensue SW, Steinhauser ML, Huffnagle GB, Lukacs NW, Strieter RM, Kunkel SL. Alteration of the Cytokine Phenotype in an Experimental Lung Granuloma Model by Inhibiting Nitric Oxide Journal of Immunology. 159: 5585-5593. PMID 9548500  1
1997 Standiford TJ, Huffnagle GB. Cytokines in Host Defense Against Pneumonia Journal of Investigative Medicine. 45: 335-345. PMID 9291689  1
1997 Huffnagle GB, Strieter RM, McNeil LK, McDonald RA, Burdick MD, Kunkel SL, Toews GB. Macrophage Inflammatory Protein-1α (MIP-1α) Is Required for the Efferent Phase of Pulmonary Cell-Mediated Immunity to a Cryptococcus neoformans Infection Journal of Immunology. 159: 318-327. PMID 9200469  1
1996 Brieland JK, Heath LA, Huffnagle GB, Remick DG, McClain MS, Hurley MC, Kunkel RK, Fantone JC, Engleberg C. Humoral Immunity and Regulation of Intrapulmonary Growth of Legionella pneumophila in the Immunocompetent Host Journal of Immunology. 157: 5002-5008. PMID 8943407  1
1996 Huffnagle GB, Toews GB, Burdick MD, Boyd MB, McAllister KS, McDonald RA, Kunkel SL, Strieter RM. Afferent Phase Production of TNF-α Is Required for the Development of Protective T Cell Immunity to Cryptococcus neoformans Journal of Immunology. 157: 4529-4536. PMID 8906831  1
1996 Huffnagle GB. Role of cytokines in T cell immunity to a pulmonary Cryptococcus neoformans infection Biological Signals. 5: 215-222. PMID 8891197  1
1996 Strieter RM, Standiford TJ, Huffnagle GB, Colletti LM, Lukacs NW, Kunkel SL. 'The good, the bad, and the ugly': The role of chemokines in models of human disease Journal of Immunology. 156: 3583-3586. PMID 8621890  1
1996 Gyetko MR, Chen GH, McDonald RA, Goodman R, Huffnagle GB, Wilkinson CC, Fuller JA, Toews GB. Urokinase is required for the pulmonary inflammatory response to Cryptococcus neoformans. A murine transgenic model. The Journal of Clinical Investigation. 97: 1818-26. PMID 8621764 DOI: 10.1172/JCI118611  1
1995 McCoy RD, Davidson BL, Roessler BJ, Huffnagle GB, Janich SL, Laing TJ, Simon RH. Pulmonary inflammation induced by incomplete or inactivated adenoviral particles. Human Gene Therapy. 6: 1553-60. PMID 8664380 DOI: 10.1089/hum.1995.6.12-1553  1
1995 Huffnagle GB, Strieter RM, Standiford TJ, McDonald RA, Burdick MD, Kunkel SL, Toews GB. The role of monocyte chemotactic protein-1 (MCP-1) in the recruitment of monocytes and CD4+ T cells during a pulmonary Cryptococcus neoformans infection Journal of Immunology. 155: 4790-4797. PMID 7594481  1
1995 McCoy RD, Davidson BL, Roessler BJ, Huffnagle GB, Simon RH. Expression of human interleukin-1 receptor antagonist in mouse lungs using a recombinant adenovirus: effects on vector-induced inflammation. Gene Therapy. 2: 437-42. PMID 7584121  1
1995 Huffnagle GB, Chen GH, Curtis JL, McDonald RA, Strieter RM, Toews GB. Down-regulation of the afferent phase of T cell-mediated pulmonary inflammation and immunity by a high melanin-producing strain of Cryptococcus neoformans Journal of Immunology. 155: 3507-3516. PMID 7561046  1
1995 Hoag KA, Street NE, Huffnagle GB, Lipscomb MF. Early cytokine production in pulmonary Cryptococcus neoformans infections distinguishes susceptible and resistant mice American Journal of Respiratory Cell and Molecular Biology. 13: 487-495. PMID 7546779  1
1994 Curtis JL, Huffnagle GB, Chen GH, Warnock ML, Gyetko MR, McDonald RA, Scott PJ, Toews GB. Experimental murine pulmonary cryptococcosis. Differences in pulmonary inflammation and lymphocyte recruitment induced by two encapsulated strains of Cryptococcus neoformans. Laboratory Investigation; a Journal of Technical Methods and Pathology. 71: 113-26. PMID 8041111  1
1994 Huffnagle GB, Lipscomb MF, Lovchik JA, Hoag KA, Street NE. The role of CD4+ and CD8+ T cells in the protective inflammatory response to a pulmonary cryptococcal infection Journal of Leukocyte Biology. 55: 35-42. PMID 7904293  1
1994 Smith RE, Strieter RM, Phan SH, Lukacs NW, Huffnagle GB, Wilke CA, Burdick MD, Lincoln P, Evanoff H, Kunkel SL. Production and function of murine macrophage inflammatory protein-1α in bleomycin-induced lung injury Journal of Immunology. 153: 4704-4712. PMID 7525712  1
1993 Lipscomb MF, Huffnagle GB, Lovchik JA, Lyons CR, Pollard AM, Yates JL. The role of T lymphocytes in pulmonary microbial defense mechanisms. Archives of Pathology & Laboratory Medicine. 117: 1225-32. PMID 8250693  1
1992 Huffnagle GB, Lipscomb MF. Animal model of human disease: Pulmonary cryptococcosis American Journal of Pathology. 141: 1517-1520. PMID 1466407  1
1991 Huffnagle GB, Yates JL, Lipscomb MF. T cell-mediated immunity in the lung: A Cryptococcus neoformans pulmonary infection model using SCID and athymic nude mice Infection and Immunity. 59: 1423-1433. PMID 1825990  1
1991 Huffnagle GB, Yates JL, Lipscomb MF. Immunity to a pulmonary Cryptococcus neoformans infection requires both CD4+ and CD8+ T cells Journal of Experimental Medicine. 173: 793-800. PMID 1672543  1
1989 Huffnagle GB, Ratcliffe MJH, Humphries EH. Bu-2, a novel avian cell surface antigen on B cells and a population of non-lymphoid cells, is expressed homogeneously in germinal centers Hybridoma. 8: 589-604. PMID 2613266  1
1986 Gaffney EV, Dell'Aquila ML, Lingenfelter SE, Huffnagle GB, Wiest DL. Characterization of a colony-stimulating factor produced by the human monocytic leukemia cell line, THP-1 Journal of Leukocyte Biology. 39: 409-421. PMID 3485167  1
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