Thomas W. North - Publications

University of California, Davis, Davis, CA 
Microbiology Biology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 North TW, Villalobos A, Hurwitz SJ, Deere JD, Higgins J, Chatterjee P, Tao S, Kauffman RC, Luciw PA, Kohler JJ, Schinazi RF. Enhanced antiretroviral therapy in rhesus macaques improves RT-SHIV viral decay kinetics. Antimicrobial Agents and Chemotherapy. 58: 3927-33. PMID 24777106 DOI: 10.1128/AAC.02522-14  0.32
2014 Deere JD, Kauffman RC, Cannavo E, Higgins J, Villalobos A, Adamson L, Schinazi RF, Luciw PA, North TW. Analysis of multiply spliced transcripts in lymphoid tissue reservoirs of rhesus macaques infected with RT-SHIV during HAART. Plos One. 9: e87914. PMID 24505331 DOI: 10.1371/journal.pone.0087914  0.32
2014 Wadford DA, Kauffman RC, Deere JD, Aoki ST, Stanton RA, Higgins J, Van Rompay KK, Villalobos A, Nettles JH, Schinazi RF, Pedersen NC, North TW. Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV. Plos One. 9: e86997. PMID 24498008 DOI: 10.1371/journal.pone.0086997  0.32
2013 Gavegnano C, Detorio MA, Bassit L, Hurwitz SJ, North TW, Schinazi RF. Cellular pharmacology and potency of HIV-1 nucleoside analogs in primary human macrophages. Antimicrobial Agents and Chemotherapy. 57: 1262-9. PMID 23263005 DOI: 10.1128/AAC.02012-12  0.32
2011 Deere JD, Schinazi RF, North TW. Simian immunodeficiency virus macaque models of HIV latency. Current Opinion in Hiv and Aids. 6: 57-61. PMID 21242894 DOI: 10.1097/COH.0b013e32834086ce  0.32
2010 Deere JD, Higgins J, Cannavo E, Villalobos A, Adamson L, Fromentin E, Schinazi RF, Luciw PA, North TW. Viral decay kinetics in the highly active antiretroviral therapy-treated rhesus macaque model of AIDS. Plos One. 5: e11640. PMID 20668516 DOI: 10.1371/journal.pone.0011640  0.32
2010 North TW, Higgins J, Deere JD, Hayes TL, Villalobos A, Adamson L, Shacklett BL, Schinazi RF, Luciw PA. Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS. Journal of Virology. 84: 2913-22. PMID 20032180 DOI: 10.1128/JVI.02356-09  0.32
2007 Van Rompay KK, Johnson JA, Blackwood EJ, Singh RP, Lipscomb J, Matthews TB, Marthas ML, Pedersen NC, Bischofberger N, Heneine W, North TW. Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection. Retrovirology. 4: 25. PMID 17417971 DOI: 10.1186/1742-4690-4-25  0.32
2007 Duong YT, Meadows DC, Srivastava IK, Gervay-Hague J, North TW. Direct inactivation of human immunodeficiency virus type 1 by a novel small-molecule entry inhibitor, DCM205. Antimicrobial Agents and Chemotherapy. 51: 1780-6. PMID 17307982 DOI: 10.1128/AAC.01001-06  0.32
2007 Meadows DC, Sanchez T, Neamati N, North TW, Gervay-Hague J. Ring substituent effects on biological activity of vinyl sulfones as inhibitors of HIV-1. Bioorganic & Medicinal Chemistry. 15: 1127-37. PMID 17074494 DOI: 10.1016/j.bmc.2006.10.017  0.32
2005 Meadows DC, Mathews TB, North TW, Hadd MJ, Kuo CL, Neamati N, Gervay-Hague J. Synthesis and biological evaluation of geminal disulfones as HIV-1 integrase inhibitors. Journal of Medicinal Chemistry. 48: 4526-34. PMID 15999991 DOI: 10.1021/jm049171v  0.32
2005 North TW, Van Rompay KK, Higgins J, Matthews TB, Wadford DA, Pedersen NC, Schinazi RF. Suppression of virus load by highly active antiretroviral therapy in rhesus macaques infected with a recombinant simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1. Journal of Virology. 79: 7349-54. PMID 15919889 DOI: 10.1128/JVI.79.12.7349-7354.2005  0.32
2005 Joshi PJ, North TW, Prasad VR. Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 677-86. PMID 15851006 DOI: 10.1016/j.ymthe.2005.01.013  0.32
2004 Hofman MJ, Higgins J, Matthews TB, Pedersen NC, Tan C, Schinazi RF, North TW. Efavirenz therapy in rhesus macaques infected with a chimera of simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1. Antimicrobial Agents and Chemotherapy. 48: 3483-90. PMID 15328115 DOI: 10.1128/AAC.48.9.3483-3490.2004  0.32
2004 North TW, Sequar G, Townsend LB, Drach JC, Barry PA. Rhesus cytomegalovirus is similar to human cytomegalovirus in susceptibility to benzimidazole nucleosides. Antimicrobial Agents and Chemotherapy. 48: 2760-5. PMID 15215146 DOI: 10.1128/AAC.48.7.2760-2765.2004  0.32
2003 Pedersen NC, North TW, Rigg R, Reading C, Higgins J, Leutenegger C, Henderson GL. 16alpha-Bromo-epiandrosterone therapy modulates experimental feline immunodeficiency virus viremia: initial enhancement leading to long-term suppression. Veterinary Immunology and Immunopathology. 94: 133-48. PMID 12909410 DOI: 10.1016/S0165-2427(03)00081-3  0.32
2003 Giuffre AC, Higgins J, Buckheit RW, North TW. Susceptibilities of simian immunodeficiency virus to protease inhibitors. Antimicrobial Agents and Chemotherapy. 47: 1756-9. PMID 12709355 DOI: 10.1128/AAC.47.5.1756-1759.2003  0.32
2003 Murry JP, Higgins J, Matthews TB, Huang VY, Van Rompay KK, Pedersen NC, North TW. Reversion of the M184V mutation in simian immunodeficiency virus reverse transcriptase is selected by tenofovir, even in the presence of lamivudine. Journal of Virology. 77: 1120-30. PMID 12502828 DOI: 10.1128/JVI.77.2.1120-1130.2003  0.32
2003 Klarmann GJ, Chen X, North TW, Preston BD. Incorporation of uracil into minus strand DNA affects the specificity of plus strand synthesis initiation during lentiviral reverse transcription. The Journal of Biological Chemistry. 278: 7902-9. PMID 12458216 DOI: 10.1074/jbc.M207223200  0.32
2002 Van Rompay KK, Matthews TB, Higgins J, Canfield DR, Tarara RP, Wainberg MA, Schinazi RF, Pedersen NC, North TW. Virulence and reduced fitness of simian immunodeficiency virus with the M184V mutation in reverse transcriptase. Journal of Virology. 76: 6083-92. PMID 12021341 DOI: 10.1128/JVI.76.12.6083-6092.2002  0.32
2002 Auwerx J, North TW, Preston BD, Klarmann GJ, De Clercq E, Balzarini J. Chimeric human immunodeficiency virus type 1 and feline immunodeficiency virus reverse transcriptases: role of the subunits in resistance/sensitivity to non-nucleoside reverse transcriptase inhibitors. Molecular Pharmacology. 61: 400-6. PMID 11809865 DOI: 10.1124/mol.61.2.400  0.32
2001 Leutenegger CM, Higgins J, Matthews TB, Tarantal AF, Luciw PA, Pedersen NC, North TW. Real-time TaqMan PCR as a specific and more sensitive alternative to the branched-chain DNA assay for quantitation of simian immunodeficiency virus RNA. Aids Research and Human Retroviruses. 17: 243-51. PMID 11177407 DOI: 10.1089/088922201750063160  0.32
2000 Klarmann GJ, Smith RA, Schinazi RF, North TW, Preston BD. Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site Journal of Biological Chemistry. 275: 359-366. PMID 10617626 DOI: 10.1074/jbc.275.1.359  0.32
1999 Smith RA, Klarmann GJ, Stray KM, Von Schwedler UK, Schinazi RF, Preston BD, North TW. A new point mutation (P157S) in the reverse transcriptase of human immunodeficiency virus type 1 confers low-level resistance to (-)-β-2',3'- dideoxy-3'-thiacytidine Antimicrobial Agents and Chemotherapy. 43: 2077-2080. PMID 10428942  0.32
1998 Elder JH, Dean GA, Hoover EA, Hoxie JA, Malim MH, Mathes L, Neil JC, North TW, Sparger E, Tompkins MB, Tompkins WA, Yamamoto J, Yuhki N, Pedersen NC, Miller RH. Lessons from the cat: feline immunodeficiency virus as a tool to develop intervention strategies against human immunodeficiency virus type 1. Aids Research and Human Retroviruses. 14: 797-801. PMID 9643379 DOI: 10.1089/aid.1998.14.797  0.32
1998 Smith RA, Remington KM, Preston BD, Schinazi RF, North TW. A novel point mutation at position 156 of reverse transcriptase from feline immunodeficiency virus confers resistance to the combination of (-)- β-2',3'-dideoxy-3'-thiacytidine and 3'-azido-3'-deoxythymidine Journal of Virology. 72: 2335-2340. PMID 9499094  0.32
1997 Hartmann K, Ferk G, North TW, Pedersen NC. Toxicity associated with high dosage 9-[(2R, 5R-2,5-dihydro-5-phosphonomethoxy)-2-furanyl]adenine therapy and attempts to abort early FIV infection Antiviral Research. 36: 11-25. PMID 9330757 DOI: 10.1016/S0166-3542(97)00030-2  0.32
1997 Smith RA, Remington KM, Lloyd RM, Schinazi RF, North TW. A novel Met-to-Thr mutation in the YMDD motif of reverse transcriptase from feline immunodeficiency virus confers resistance to oxathiolane nucleosides Journal of Virology. 71: 2357-2362. PMID 9032372  0.32
1996 Zhu YQ, Remington KM, North TW. Mutants of feline immunodeficiency virus resistant to 2',3'-dideoxy- 2',3'-didehydrothymidine Antimicrobial Agents and Chemotherapy. 40: 1983-1987. PMID 8878567  0.32
1996 Medlin HK, Zhu YQ, Remington KM, Phillips TR, North TW. Selection and characterization of a mutant of feline immunodeficiency virus resistant to 2′ ,3 ′ -dideoxycytidine Antimicrobial Agents and Chemotherapy. 40: 953-957. PMID 8849258  0.32
1996 Arts EJ, Stetor SR, Li X, Rausch JW, Howard KJ, Ehresmann B, North TW, Wöhrl BM, Goody RS, Wainberg MA, Le Grice SFJ. Initiation of (-) strand DNA synthesis from tRNALys3 on lentiviral RNAs: Implications of specific HIV-1 RNA-tRNALys3 interactions inhibiting primer utilization by retroviral reverse transcriptases Proceedings of the National Academy of Sciences of the United States of America. 93: 10063-10068. PMID 8816751  0.32
1996 Chen H, McBroom DG, Zhu YQ, Gold L, North TW. Inhibitory RNA ligand to reverse transcriptase from feline immunodeficiency virus Biochemistry. 35: 6923-6930. PMID 8639644 DOI: 10.1021/bi9600106  0.32
1996 LaCasse RA, Remington KM, North TW. The Mutation Frequency of Feline Immunodeficiency Virus Enhanced by 3′-Azido-3′-deoxythymidine Journal of Acquired Immune Deficiency Syndromes. 12: 26-32. PMID 8624757  0.32
1995 North TW, Lacasse RA. Testing anti–HIV drugs in the FIV model Nature Medicine. 1: 410-411. PMID 7585083 DOI: 10.1038/nm0595-410  0.32
1995 Kimberlin DW, Kern ER, Sidwell RW, North TW, Whitley RJ. Models of antiviral resistance Antiviral Research. 26: 415-422. PMID 7574543 DOI: 10.1016/0166-3542(95)00030-P  0.32
1994 Forbes SH, Knudsen KL, North TW, Allendorf FW. One of two growth hormone genes in coho salmon is sex-linked. Proceedings of the National Academy of Sciences of the United States of America. 91: 1628-31. PMID 8127856  0.32
1994 Gobert JM, Remington KM, Ya Qi Zhu, North TW. Multiple-drug-resistant mutants of feline immunodeficiency virus selected with 2',3'-dideoxyinosine alone and in combination with 3'-azido-3'- deoxythymidine Antimicrobial Agents and Chemotherapy. 38: 861-864. PMID 8031060  0.32
1994 North TW, Hansen GL, Zhu Y, Griffin JA, Shih CK. Expression of reverse transcriptase from feline immunodeficiency virus in Escherichia coli Antimicrobial Agents and Chemotherapy. 38: 388-391. PMID 7514859  0.32
1994 Remington KM, Zhu YQ, Phillips TR, North TW. Rapid phenotypic reversion of zidovudine-resistant feline immunodeficiency virus without loss of drug-resistant reverse transcriptase Journal of Virology. 68: 632-637. PMID 7507182  0.32
1993 Barlough JE, North TW, Oxford CL, Remington KM, Dandekar S, Nixon Ellis M, Pedersen NC. Feline immunodeficiency virus infection of cats as a model to test the effect of certain in vitro selection pressures on the infectivity and virulence of resultant lentivirus variants Antiviral Research. 22: 259-272. PMID 8279815 DOI: 10.1016/0166-3542(93)90036-I  0.32
1992 Cronn RC, Remington KM, Preston BD, North TW. Inhibition of reverse transcriptase from feline immunodeficiency virus by analogs of 2′-deoxyadenosine-5′-triphosphate Biochemical Pharmacology. 44: 1375-1381. PMID 1384501 DOI: 10.1016/0006-2952(92)90539-U  0.32
1992 Cronn RC, Whitmer JD, North TW. RNase H activity associated with reverse transcriptase from feline immunodeficiency virus. Journal of Virology. 66: 1215-8. PMID 1370549  0.32
1991 Remington KM, Chesebro B, Wehrly K, Pedersen NC, North TW. Mutants of feline immunodeficiency virus resistant to 3′ - azido-3′ -deoxythymidine Journal of Virology. 65: 308-312. PMID 1845891  0.32
1990 North TW, Cronn RC, Remington KM, Tandberg RT. Direct comparisons of inhibitor sensitivities of reverse transcriptases from feline and human immunodeficiency viruses Antimicrobial Agents and Chemotherapy. 34: 1505-1507. PMID 1699491  0.32
1990 North TW, Cronn RC, Remington KM, Tandberg RT, Judd RC. Characterization of reverse transcriptase from feline immunodeficiency virus Journal of Biological Chemistry. 265: 5121-5128. PMID 1690735  0.32
1989 North TW, North GLT, Pedersen NC. Feline immunodeficiency virus, a model for reverse transcriptase-targeted chemotherapy for acquired immune deficiency syndrome Antimicrobial Agents and Chemotherapy. 33: 915-919. PMID 2475068  0.32
1987 North TW, Wyler DJ. DNA synthesis in promastigotes of Leishmania major and L. donovani Molecular and Biochemical Parasitology. 22: 215-221. PMID 2437451 DOI: 10.1016/0166-6851(87)90052-1  0.32
1984 North TW. Inhibition of Herpes Simplex Virus Replication by Purine Deoxyribonucleosides Cancer Research. 44: 1415-1419. PMID 6322976  0.32
1983 North TW. Effects of 9-β-d-arabinofuranosyladenine and 1-β-d-arabinofuranosylcytosine on levels of deoxyribonucleic acid precursors in uninfected and herpes simplex virus-infected cells Biochemical Pharmacology. 32: 3862-3864. PMID 6661258 DOI: 10.1016/0006-2952(83)90162-4  0.32
1983 North TW, O'Connor L, Abushanab E, Panzica RP. Effects of chirality in 9-(2-hydroxy-3-nonyl)adenine upon deoxyribonucleic acid synthesis in herpes simplex virus-infected cells Biochemical Pharmacology. 32: 3541-3546. PMID 6316987 DOI: 10.1016/0006-2952(83)90300-3  0.32
1981 North TW, Mathews CK. Tetrahydrouridine specifically facilitates deoxycytidine incorporation into herpes simplex virus DNA Journal of Virology. 37: 987-993. PMID 6262539  0.32
1980 Shannon WM, Arnett G, Schabel FM, North TW, Cohen SS. Erythro-9-(2-hydroxy-3-nonyl)adenine alone and in combination with 9-β-D-arabinofuranosyladenine in treatment of systemic herpesvirus infections in mice Antimicrobial Agents and Chemotherapy. 18: 598-603. PMID 6255863  0.32
1980 North TW, Bestwick RK, Mathews CK. Detection of activities that interfere with the enzymatic assay of deoxyribonucleoside 5'-triphosphates Journal of Biological Chemistry. 255: 6640-6645. PMID 6248528  0.32
1979 Mathews CK, North TW, Prem Veer Reddy G. Multienzyme complexes in DNA precursor biosynthesis Advances in Enzyme Regulation. 17: 133-156. PMID 393088 DOI: 10.1016/0065-2571(79)90011-6  0.32
1979 North TW, Cohen SS. Aranucleosides and aranucleotides in viral chemotherapy Pharmacology and Therapeutics. 4: 81-108. PMID 88745 DOI: 10.1016/0163-7258(79)90016-0  0.32
1978 North TW, Cohen SS. Erythro-9-(2-hydroxy-3-nonyl)adenine as a specific inhibitor of herpes simplex virus replication in the presence and absence of adenosine analogues Proceedings of the National Academy of Sciences of the United States of America. 75: 4684-4688. PMID 216993  0.32
1977 North TW, Mathews CK. T4 phage-coded deoxycytidylate hydroxymethylase: Purification and studies on intermolecular interactions Biochemical and Biophysical Research Communications. 77: 898-904. PMID 332172 DOI: 10.1016/S0006-291X(77)80062-4  0.32
1976 North TW, Stafford ME, Mathews CK. Biochemistry of DNA defective mutants of bacteriophage T4. VI. Biological functions of gene 42 Journal of Virology. 17: 973-982. PMID 943575  0.32
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