| Year |
Citation |
Score |
| 2022 |
Hali M, Wadzinski BE, Kowluru A. Alpha4 contributes to the dysfunction of the pancreatic beta cell under metabolic stress. Molecular and Cellular Endocrinology. 557: 111754. PMID 35987388 DOI: 10.1016/j.mce.2022.111754 |
0.311 |
|
| 2022 |
Sontag JM, Schuhmacher D, Taleski G, Jordan A, Khan S, Hoffman A, Gomez RJ, Mazalouskas MD, Hanks SK, Spiller BW, Sontag E, Wadzinski BE. A new paradigm for regulation of protein phosphatase 2A function via Src and Fyn kinase-mediated tyrosine phosphorylation. The Journal of Biological Chemistry. 102248. PMID 35820485 DOI: 10.1016/j.jbc.2022.102248 |
0.374 |
|
| 2020 |
Frohner IE, Mudrak I, Schüchner S, Anrather D, Hartl M, Sontag JM, Sontag E, Wadzinski BE, Preglej T, Ellmeier W, Ogris E. PP2A Phospho-Tyr Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2A Modifications Including Leu Methylation. Cell Reports. 30: 3171-3182.e6. PMID 32130916 DOI: 10.1016/J.Celrep.2020.02.035 |
0.393 |
|
| 2017 |
Eleftheriadou O, Boguslavskyi A, Longman MR, Cowan J, Francois A, Heads RJ, Wadzinski BE, Ryan A, Shattock MJ, Snabaitis AK. Expression and regulation of type 2A protein phosphatases and alpha4 signalling in cardiac health and hypertrophy. Basic Research in Cardiology. 112: 37. PMID 28526910 DOI: 10.1007/S00395-017-0625-2 |
0.508 |
|
| 2016 |
LeNoue-Newton ML, Wadzinski BE, Spiller BW. The three Type 2A protein phosphatases, PP2Ac, PP4c and PP6c, are differentially regulated by Alpha4. Biochemical and Biophysical Research Communications. PMID 27169767 DOI: 10.1016/J.Bbrc.2016.05.036 |
0.466 |
|
| 2014 |
Mo ST, Chiang SJ, Lai TY, Cheng YL, Chung CE, Kuo SC, Reece KM, Chen YC, Chang NS, Wadzinski BE, Chiang CW. Visualization of subunit interactions and ternary complexes of protein phosphatase 2A in mammalian cells. Plos One. 9: e116074. PMID 25536081 DOI: 10.1371/Journal.Pone.0116074 |
0.457 |
|
| 2014 |
Williams BC, Filter JJ, Blake-Hodek KA, Wadzinski BE, Fuda NJ, Shalloway D, Goldberg ML. Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers. Elife. 3: e01695. PMID 24618897 DOI: 10.7554/Elife.01695 |
0.403 |
|
| 2014 |
Mazalouskas MD, Godoy-Ruiz R, Weber DJ, Zimmer DB, Honkanen RE, Wadzinski BE. Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1. The Journal of Biological Chemistry. 289: 4219-32. PMID 24371145 DOI: 10.1074/Jbc.M113.518514 |
0.486 |
|
| 2014 |
Arora DK, Machhadieh B, Matti A, Wadzinski BE, Ramanadham S, Kowluru A. High glucose exposure promotes activation of protein phosphatase 2A in rodent islets and INS-1 832/13 β-cells by increasing the posttranslational carboxylmethylation of its catalytic subunit. Endocrinology. 155: 380-91. PMID 24265448 DOI: 10.1210/En.2013-1773 |
0.364 |
|
| 2014 |
Williams BC, Filter JJ, Blake-Hodek KA, Wadzinski BE, Fuda NJ, Shalloway D, Goldberg ML. Author response: Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers Elife. DOI: 10.7554/Elife.01695.026 |
0.375 |
|
| 2014 |
Eleftheriadou O, Longman, Boguslavskyi A, Ryan A, Wadzinski B, Shattock M, Snabaitis A. Expression Of Type 2A Protein Phosphatases In Cardiac Health And Disease Heart. 100. DOI: 10.1136/Heartjnl-2014-306916.49 |
0.432 |
|
| 2013 |
Kamoun M, Filali M, Murray MV, Awasthi S, Wadzinski BE. Protein phosphatase 2A family members (PP2A and PP6) associate with U1 snRNP and the spliceosome during pre-mRNA splicing. Biochemical and Biophysical Research Communications. 440: 306-11. PMID 24064353 DOI: 10.1016/J.Bbrc.2013.09.068 |
0.409 |
|
| 2013 |
Jiang L, Stanevich V, Satyshur KA, Kong M, Watkins GR, Wadzinski BE, Sengupta R, Xing Y. Structural basis of protein phosphatase 2A stable latency. Nature Communications. 4: 1699. PMID 23591866 DOI: 10.1038/Ncomms2663 |
0.415 |
|
| 2012 |
Wang N, Leung HT, Mazalouskas MD, Watkins GR, Gomez RJ, Wadzinski BE. Essential roles of the Tap42-regulated protein phosphatase 2A (PP2A) family in wing imaginal disc development of Drosophila melanogaster. Plos One. 7: e38569. PMID 22701670 DOI: 10.1371/Journal.Pone.0038569 |
0.406 |
|
| 2012 |
Watkins GR, Wang N, Mazalouskas MD, Gomez RJ, Guthrie CR, Kraemer BC, Schweiger S, Spiller BW, Wadzinski BE. Monoubiquitination promotes calpain cleavage of the protein phosphatase 2A (PP2A) regulatory subunit α4, altering PP2A stability and microtubule-associated protein phosphorylation. The Journal of Biological Chemistry. 287: 24207-15. PMID 22613722 DOI: 10.1074/Jbc.M112.368613 |
0.437 |
|
| 2011 |
LeNoue-Newton M, Watkins GR, Zou P, Germane KL, McCorvey LR, Wadzinski BE, Spiller BW. The E3 ubiquitin ligase- and protein phosphatase 2A (PP2A)-binding domains of the Alpha4 protein are both required for Alpha4 to inhibit PP2A degradation. The Journal of Biological Chemistry. 286: 17665-71. PMID 21454489 DOI: 10.1074/Jbc.M111.222414 |
0.477 |
|
| 2011 |
Panosian TD, Nannemann DP, Watkins GR, Phelan VV, McDonald WH, Wadzinski BE, Bachmann BO, Iverson TM. Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycle. The Journal of Biological Chemistry. 286: 8043-54. PMID 21193409 DOI: 10.1074/Jbc.M110.201350 |
0.402 |
|
| 2010 |
Widau RC, Jin Y, Dixon SA, Wadzinski BE, Gallagher PJ. Protein phosphatase 2A (PP2A) holoenzymes regulate death-associated protein kinase (DAPK) in ceramide-induced anoikis. The Journal of Biological Chemistry. 285: 13827-38. PMID 20220139 DOI: 10.1074/Jbc.M109.085076 |
0.528 |
|
| 2010 |
McConnell JL, Watkins GR, Soss SE, Franz HS, McCorvey LR, Spiller BW, Chazin WJ, Wadzinski BE. Alpha4 is a ubiquitin-binding protein that regulates protein serine/threonine phosphatase 2A ubiquitination. Biochemistry. 49: 1713-8. PMID 20092282 DOI: 10.1021/Bi901837H |
0.747 |
|
| 2009 |
Reece KM, Mazalouskas MD, Wadzinski BE. The Balpha and Bdelta regulatory subunits of PP2A are necessary for assembly of the CaMKIV.PP2A signaling complex. Biochemical and Biophysical Research Communications. 386: 582-7. PMID 19538941 DOI: 10.1016/J.Bbrc.2009.06.062 |
0.493 |
|
| 2009 |
McConnell JL, Wadzinski BE. Targeting protein serine/threonine phosphatases for drug development. Molecular Pharmacology. 75: 1249-61. PMID 19299564 DOI: 10.1124/Mol.108.053140 |
0.734 |
|
| 2009 |
Guo S, Burnette R, Zhao L, Vanderford NL, Poitout V, Hagman DK, Henderson E, Ozcan S, Wadzinski BE, Stein R. The stability and transactivation potential of the mammalian MafA transcription factor are regulated by serine 65 phosphorylation. The Journal of Biological Chemistry. 284: 759-65. PMID 19004825 DOI: 10.1074/Jbc.M806314200 |
0.477 |
|
| 2008 |
Wang N, Leung HT, Pak WL, Carl YT, Wadzinski BE, Shieh BH. Role of protein phosphatase 2A in regulating the visual signaling in Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1444-51. PMID 18256265 DOI: 10.1523/Jneurosci.5134-07.2008 |
0.436 |
|
| 2007 |
McConnell JL, Gomez RJ, McCorvey LR, Law BK, Wadzinski BE. Identification of a PP2A-interacting protein that functions as a negative regulator of phosphatase activity in the ATM/ATR signaling pathway. Oncogene. 26: 6021-30. PMID 17384681 DOI: 10.1038/Sj.Onc.1210406 |
0.769 |
|
| 2007 |
Adams DG, Wadzinski BE. Isolation and characterization of PP2A holoenzymes containing FLAG-tagged B subunits. Methods in Molecular Biology (Clifton, N.J.). 365: 101-11. PMID 17200557 DOI: 10.1385/1-59745-267-X:101 |
0.519 |
|
| 2007 |
Wegner AM, McConnell JL, Blakely RD, Wadzinski BE. An automated fluorescence-based method for continuous assay of PP2A activity. Methods in Molecular Biology (Clifton, N.J.). 365: 61-9. PMID 17200554 DOI: 10.1385/1-59745-267-X:61 |
0.725 |
|
| 2006 |
Khoo MS, Li J, Singh MV, Yang Y, Kannankeril P, Wu Y, Grueter CE, Guan X, Oddis CV, Zhang R, Mendes L, Ni G, Madu EC, Yang J, Bass M, ... ... Wadzinski BE, et al. Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy. Circulation. 114: 1352-9. PMID 16982937 DOI: 10.1161/Circulationaha.106.644583 |
0.302 |
|
| 2006 |
Codreanu SG, Adams DG, Dawson ES, Wadzinski BE, Liebler DC. Inhibition of protein phosphatase 2A activity by selective electrophile alkylation damage. Biochemistry. 45: 10020-9. PMID 16906760 DOI: 10.1021/Bi060551N |
0.527 |
|
| 2006 |
Veluthakal R, Wadzinski BE, Kowluru A. Localization of a nuclear serine/threonine protein phosphatase in insulin-secreting INS-1 cells: potential regulation by IL-1beta. Apoptosis : An International Journal On Programmed Cell Death. 11: 1401-11. PMID 16830232 DOI: 10.1007/S10495-006-8371-1 |
0.395 |
|
| 2006 |
Bridges D, MacDonald JA, Wadzinski B, Moorhead GB. Identification and characterization of D-AKAP1 as a major adipocyte PKA and PP1 binding protein. Biochemical and Biophysical Research Communications. 346: 351-7. PMID 16756943 DOI: 10.1016/J.Bbrc.2006.05.138 |
0.51 |
|
| 2006 |
Fritz A, Brayer KJ, McCormick N, Adams DG, Wadzinski BE, Vaillancourt RR. Phosphorylation of serine 526 is required for MEKK3 activity, and association with 14-3-3 blocks dephosphorylation. The Journal of Biological Chemistry. 281: 6236-45. PMID 16407301 DOI: 10.1074/Jbc.M509249200 |
0.447 |
|
| 2005 |
Adams DG, Coffee RL, Zhang H, Pelech S, Strack S, Wadzinski BE. Positive regulation of Raf1-MEK1/2-ERK1/2 signaling by protein serine/threonine phosphatase 2A holoenzymes. The Journal of Biological Chemistry. 280: 42644-54. PMID 16239230 DOI: 10.1074/Jbc.M502464200 |
0.526 |
|
| 2005 |
Van Kanegan MJ, Adams DG, Wadzinski BE, Strack S. Distinct protein phosphatase 2A heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and Akt. The Journal of Biological Chemistry. 280: 36029-36. PMID 16129692 DOI: 10.1074/Jbc.M506986200 |
0.496 |
|
| 2005 |
Kray AE, Carter RS, Pennington KN, Gomez RJ, Sanders LE, Llanes JM, Khan WN, Ballard DW, Wadzinski BE. Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A. The Journal of Biological Chemistry. 280: 35974-82. PMID 16126728 DOI: 10.1074/Jbc.M506093200 |
0.523 |
|
| 2005 |
Zhang X, Ozawa Y, Lee H, Wen YD, Tan TH, Wadzinski BE, Seto E. Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4. Genes & Development. 19: 827-39. PMID 15805470 DOI: 10.1101/Gad.1286005 |
0.482 |
|
| 2004 |
Garriga J, Jayaraman AL, Limón A, Jayadeva G, Sotillo E, Truongcao M, Patsialou A, Wadzinski BE, Graña X. A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130. Cell Cycle (Georgetown, Tex.). 3: 1320-30. PMID 15467457 DOI: 10.4161/Cc.3.10.1183 |
0.487 |
|
| 2004 |
Wells L, Kreppel LK, Comer FI, Wadzinski BE, Hart GW. O-GlcNAc transferase is in a functional complex with protein phosphatase 1 catalytic subunits. The Journal of Biological Chemistry. 279: 38466-70. PMID 15247246 DOI: 10.1074/Jbc.M406481200 |
0.409 |
|
| 2004 |
Anderson KA, Noeldner PK, Reece K, Wadzinski BE, Means AR. Regulation and function of the calcium/calmodulin-dependent protein kinase IV/protein serine/threonine phosphatase 2A signaling complex. The Journal of Biological Chemistry. 279: 31708-16. PMID 15143065 DOI: 10.1074/Jbc.M404523200 |
0.431 |
|
| 2003 |
Colbran RJ, Carmody LC, Bauman PA, Wadzinski BE, Bass MA. Analysis of specific interactions of native protein phosphatase 1 isoforms with targeting subunits. Methods in Enzymology. 366: 156-75. PMID 14674248 DOI: 10.1016/S0076-6879(03)66014-3 |
0.469 |
|
| 2003 |
Kloeker S, Reed R, McConnell JL, Chang D, Tran K, Westphal RS, Law BK, Colbran RJ, Kamoun M, Campbell KS, Wadzinski BE. Parallel purification of three catalytic subunits of the protein serine/threonine phosphatase 2A family (PP2A(C), PP4(C), and PP6(C)) and analysis of the interaction of PP2A(C) with alpha4 protein. Protein Expression and Purification. 31: 19-33. PMID 12963337 DOI: 10.1016/S1046-5928(03)00141-4 |
0.743 |
|
| 2003 |
Dagda RK, Zaucha JA, Wadzinski BE, Strack S. A developmentally regulated, neuron-specific splice variant of the variable subunit Bbeta targets protein phosphatase 2A to mitochondria and modulates apoptosis. The Journal of Biological Chemistry. 278: 24976-85. PMID 12716901 DOI: 10.1074/Jbc.M302832200 |
0.402 |
|
| 2003 |
Kabashima T, Kawaguchi T, Wadzinski BE, Uyeda K. Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver. Proceedings of the National Academy of Sciences of the United States of America. 100: 5107-12. PMID 12684532 DOI: 10.1073/Pnas.0730817100 |
0.455 |
|
| 2003 |
Colbran RJ, Carmody LC, Bauman PA, Wadzinski BE, Bass MA. [14] Analysis of Specific Interactions of Native Protein Phosphatase 1 Isoforms with Targeting Subunits Methods in Enzymology. 366: 156-175. DOI: 10.1016/S0076-6879(03)66014-3 |
0.343 |
|
| 2002 |
Strayhorn WD, Wadzinski BE. A novel in vitro assay for deubiquitination of I kappa B alpha. Archives of Biochemistry and Biophysics. 400: 76-84. PMID 11913973 DOI: 10.1006/Abbi.2002.2760 |
0.714 |
|
| 2001 |
Yang J, Fan GH, Wadzinski BE, Sakurai H, Richmond A. Protein phosphatase 2A interacts with and directly dephosphorylates RelA. The Journal of Biological Chemistry. 276: 47828-33. PMID 11591705 DOI: 10.1074/Jbc.M106103200 |
0.499 |
|
| 2001 |
Chiang CW, Harris G, Ellig C, Masters SC, Subramanian R, Shenolikar S, Wadzinski BE, Yang E. Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3-dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation. Blood. 97: 1289-97. PMID 11222372 DOI: 10.1182/Blood.V97.5.1289 |
0.461 |
|
| 2000 |
Bauman AL, Apparsundaram S, Ramamoorthy S, Wadzinski BE, Vaughan RA, Blakely RD. Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7571-8. PMID 11027216 DOI: 10.1523/Jneurosci.20-20-07571.2000 |
0.427 |
|
| 2000 |
Liu M, Parker LL, Wadzinski BE, Shieh BH. Reversible phosphorylation of the signal transduction complex in Drosophila photoreceptors. The Journal of Biological Chemistry. 275: 12194-9. PMID 10766855 DOI: 10.1074/Jbc.275.16.12194 |
0.457 |
|
| 1999 |
MacMillan LB, Bass MA, Cheng N, Howard EF, Tamura M, Strack S, Wadzinski BE, Colbran RJ. Brain actin-associated protein phosphatase 1 holoenzymes containing spinophilin, neurabin, and selected catalytic subunit isoforms. The Journal of Biological Chemistry. 274: 35845-54. PMID 10585469 DOI: 10.1074/Jbc.274.50.35845 |
0.384 |
|
| 1999 |
Price NE, Wadzinski B, Mumby MC. An anchoring factor targets protein phosphatase 2A to brain microtubules. Brain Research. Molecular Brain Research. 73: 68-77. PMID 10581399 DOI: 10.1016/S0169-328X(99)00237-5 |
0.468 |
|
| 1999 |
Strack S, Chang D, Zaucha JA, Colbran RJ, Wadzinski BE. Cloning and characterization of B delta, a novel regulatory subunit of protein phosphatase 2A. Febs Letters. 460: 462-6. PMID 10556517 DOI: 10.1016/S0014-5793(99)01377-0 |
0.477 |
|
| 1999 |
Strack S, Kini S, Ebner FF, Wadzinski BE, Colbran RJ. Differential cellular and subcellular localization of protein phosphatase 1 isoforms in brain. The Journal of Comparative Neurology. 413: 373-84. PMID 10502246 DOI: 10.1002/(Sici)1096-9861(19991025)413:3<373::Aid-Cne2>3.0.Co;2-Z |
0.382 |
|
| 1999 |
Filali M, Li S, Kim HW, Wadzinski B, Kamoun M. Identification of a type 6 protein ser/thr phosphatase regulated by interleukin-2 stimulation Journal of Cellular Biochemistry. 73: 153-163. PMID 10227379 DOI: 10.1002/(Sici)1097-4644(19990501)73:2<153::Aid-Jcb2>3.0.Co;2-7 |
0.384 |
|
| 1999 |
Bryant JC, Westphal RS, Wadzinski BE. Methylated C-terminal leucine residue of PP2A catalytic subunit is important for binding of regulatory Bα subunit Biochemical Journal. 339: 241-246. PMID 10191253 DOI: 10.1042/0264-6021:3390241 |
0.336 |
|
| 1999 |
Kloeker S, Wadzinski BE. Purification and identification of a novel subunit of protein serine/threonine phosphatase 4 Journal of Biological Chemistry. 274: 5339-5347. PMID 10026142 DOI: 10.1074/Jbc.274.9.5339 |
0.471 |
|
| 1999 |
Westphal RS, Coffee RL, Marotta A, Pelech SL, Wadzinski BE. Identification of kinase-phosphatase signaling modules composed of p70 S6 kinase-protein phosphatase 2A (PP2A) and p21-activated kinase-PP2A. The Journal of Biological Chemistry. 274: 687-92. PMID 9873003 DOI: 10.1074/Jbc.274.2.687 |
0.48 |
|
| 1999 |
Bryant JC, Westphal RS, Wadzinski BE. Methylated C-Terminal Leucine Residue Of Pp2A Catalytic Subunit Is Important For Binding Of Regulatory Balpha Subunit Biochemical Journal. 339: 241-246. DOI: 10.1042/Bj3390241 |
0.439 |
|
| 1998 |
Zaucha JA, Westphal RS, Wadzinski BE. protein phosphatase 2A regulatory subunits. cDNA cloning and analysis of mRNA expression Methods in Molecular Biology (Clifton, N.J.). 93: 279-291. PMID 9664545 DOI: 10.1385/0-89603-468-2:279 |
0.391 |
|
| 1998 |
Westphal RS, Anderson KA, Means AR, Wadzinski BE. A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A. Science (New York, N.Y.). 280: 1258-61. PMID 9596578 DOI: 10.1126/Science.280.5367.1258 |
0.492 |
|
| 1998 |
Strack S, Zaucha JA, Ebner FF, Colbran RJ, Wadzinski BE. Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits. The Journal of Comparative Neurology. 392: 515-27. PMID 9514514 DOI: 10.1002/(Sici)1096-9861(19980323)392:4<515::Aid-Cne8>3.0.Co;2-3 |
0.455 |
|
| 1997 |
Strack S, Westphal RS, Colbran RJ, Ebner FF, Wadzinski BE. Protein serine/threonine phosphatase 1 and 2A associate with and dephosphorylate neurofilaments. Brain Research. Molecular Brain Research. 49: 15-28. PMID 9387859 DOI: 10.1016/S0169-328X(97)00117-4 |
0.514 |
|
| 1997 |
Colbran RJ, Bass MA, McNeill RB, Bollen M, Zhao S, Wadzinski BE, Strack S. Association of brain protein phosphatase 1 with cytoskeletal targeting/regulatory subunits. Journal of Neurochemistry. 69: 920-9. PMID 9282913 DOI: 10.1046/J.1471-4159.1997.69030920.X |
0.425 |
|
| 1997 |
Strack S, Barban MA, Wadzinski BE, Colbran RJ. Differential inactivation of postsynaptic density-associated and soluble Ca2+/calmodulin-dependent protein kinase II by protein phosphatases 1 and 2A. Journal of Neurochemistry. 68: 2119-28. PMID 9109540 DOI: 10.1046/J.1471-4159.1997.68052119.X |
0.458 |
|
| 1993 |
Wadzinski BE, Wheat WH, Jaspers S, Peruski LF, Lickteig RL, Johnson GL, Klemm DJ. Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation Molecular and Cellular Biology. 13: 2822-2834. PMID 8386317 DOI: 10.1128/Mcb.13.5.2822 |
0.464 |
|
| 1990 |
Wadzinski BE, Heasley LE, Johnson GL. Multiplicity of protein serine-threonine phosphatases in PC12 pheochromocytoma and FTO-2B hepatoma cells. The Journal of Biological Chemistry. 265: 21504-8. PMID 2174876 |
0.392 |
|
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