Norman Letvin - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Immunology, Microbiology Biology

450 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tomalka JA, Pelletier AN, Fourati S, Latif MB, Sharma A, Furr K, Carlson K, Lifton M, Gonzalez A, Wilkinson P, Franchini G, Parks R, Letvin N, Yates N, Seaton K, et al. The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination. Nature Immunology. PMID 34556879 DOI: 10.1038/s41590-021-01026-9  1
2021 Reddi TS, Merkl PE, Lim SY, Letvin NL, Knipe DM. Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genes. Plos Pathogens. 17: e1009281. PMID 33524065 DOI: 10.1371/journal.ppat.1009281  1
2021 Eslamizar L, Petrovas C, Leggat DJ, Furr K, Lifton ML, Levine G, Ma S, Fletez-Brant C, Hoyland W, Prabhakaran M, Narpala S, Boswell K, Yamamoto T, Liao HX, Pickup D, ... ... Letvin NL, et al. Recombinant MVA-prime elicits neutralizing antibody responses by inducing antigen-specific B cells in the germinal center. Npj Vaccines. 6: 15. PMID 33495459 DOI: 10.1038/s41541-020-00277-1  1
2017 Saunders KO, Nicely NI, Wiehe K, Bonsignori M, Meyerhoff RR, Parks R, Walkowicz WE, Aussedat B, Wu NR, Cai F, Vohra Y, Park PK, Eaton A, Go EP, Sutherland LL, ... ... Letvin NL, et al. Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates. Cell Reports. 18: 2175-2188. PMID 28249163 DOI: 10.1016/J.Celrep.2017.02.003  1
2017 Saunders KO, Nicely NI, Aussedat B, Wiehe K, Parks R, Vohra Y, Walkowicz WE, Park PK, Eaton A, Sutherland LL, Scearce R, Wu N, Bonsignori M, Meyerhoff RR, Lloyd KE, ... ... Letvin N, et al. HIV Envelope vaccination elicits asparagine 332 glycan-dependent antibodies that resemble broadly neutralizing antibody precursors Cell Reports. DOI: 10.2210/Pdb5Iie/Pdb  1
2016 Luo K, Liao HX, Zhang R, Easterhoff D, Wiehe K, Gurley TC, Armand LC, Allen AA, Von Holle TA, Marshall DJ, Whitesides JF, Pritchett J, Foulger A, Hernandez G, Parks R, ... ... Letvin NL, et al. Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques. Jci Insight. 1: e88522. PMID 27942585 DOI: 10.1172/Jci.Insight.88522  1
2016 Krebs KC, Tian M, Asmal M, Ling B, Nelson K, Henry K, Gibson R, Li Y, Han W, Shattock RJ, Veazey RS, Letvin N, Arts EJ, Gao Y. Infection of rhesus macaques with a pool of simian immunodeficiency virus with the envelope genes from acute HIV-1 infections. Aids Research and Therapy. 13: 41. PMID 27906032 DOI: 10.1186/S12981-016-0125-8  1
2016 Asmal M, Lane S, Tian M, Nickel G, Venner C, Dirk B, Dikeakos J, Luedemann C, Mach L, Balachandran H, Buzby A, Rao S, Letvin N, Gao Y, Arts EJ. Pathogenic infection of Rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV-1 infections. Virology. 499: 298-312. PMID 27723488 DOI: 10.1016/J.Virol.2016.09.021  1
2016 Keating SM, Heitman JW, Wu S, Deng X, Stacey AR, Zahn RC, de la Rosa M, Finstad SL, Lifson JD, Piatak M, Gauduin MC, Kessler BM, Ternette N, Carville A, Johnson RP, ... ... Letvin NL, et al. Magnitude and quality of cytokine and chemokine storm during acute infection distinguish non-progressive and progressive simian immunodeficiency virus infections of nonhuman primates. Journal of Virology. PMID 27630228 DOI: 10.1128/Jvi.01061-16  1
2015 Qin L, Jiang G, Han J, Letvin NL. Regulatory T Cells Modulate DNA Vaccine Immunogenicity at Early Time via Functional CD4(+) T Cells and Antigen Duration. Frontiers in Immunology. 6: 510. PMID 26483796 DOI: 10.3389/fimmu.2015.00510  1
2015 Santra S, Tomaras GD, Warrier R, Nicely NI, Liao HX, Pollara J, Liu P, Alam SM, Zhang R, Cocklin SL, Shen X, Duffy R, Xia SM, Schutte RJ, Pemble Iv CW, ... ... Letvin NL, et al. Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques. Plos Pathogens. 11: e1005042. PMID 26237403 DOI: 10.1371/Journal.Ppat.1005042  1
2015 Korioth-Schmitz B, Perley CC, Sixsmith JD, Click EM, Lee S, Letvin NL, Frothingham R. Rhesus immune responses to SIV Gag expressed by recombinant BCG vectors are independent from pre-existing mycobacterial immunity. Vaccine. 33: 5715-22. PMID 26192357 DOI: 10.1016/j.vaccine.2015.07.010  1
2015 Hulot SL, Korber B, Giorgi EE, Vandergrift N, Saunders KO, Balachandran H, Mach LV, Lifton MA, Pantaleo G, Tartaglia J, Phogat S, Jacobs B, Kibler K, Perdiguero B, Gomez CE, ... ... Letvin NL, et al. Comparison of Immunogenicity in Rhesus Macaques of Transmitted-Founder, HIV-1 Group M Consensus, and Trivalent Mosaic Envelope Vaccines Formulated as a DNA Prime, NYVAC, and Envelope Protein Boost. Journal of Virology. 89: 6462-80. PMID 25855741 DOI: 10.1128/Jvi.00383-15  1
2015 Asmal M, Luedemann C, Lavine CL, Mach LV, Balachandran H, Brinkley C, Denny TN, Lewis MG, Anderson H, Pal R, Sok D, Le K, Pauthner M, Hahn BH, Shaw GM, ... ... Letvin NL, et al. Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes. Virology. 475: 37-45. PMID 25462344 DOI: 10.1016/J.Virol.2014.10.032  1
2015 Asmal M, Luedemann C, Lavine CL, Mach LV, Balachandran H, Brinkley C, Denny TN, Lewis MG, Anderson H, Pal R, Sok D, Le K, Pauthner M, Hahn BH, Shaw GM, ... ... Letvin NL, et al. Corrigendum to: Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes [Virology 475 (2015) 37-45] Virology. 478: 155-158. DOI: 10.1016/J.Virol.2015.01.023  1
2014 Panas MW, Sixsmith JD, White K, Korioth-Schmitz B, Shields ST, Moy BT, Lee S, Schmitz JE, Jacobs WR, Porcelli SA, Haynes BF, Letvin NL, Gillard GO. Gene deletions in Mycobacterium bovis BCG stimulate increased CD8+ T cell responses. Infection and Immunity. 82: 5317-26. PMID 25287928 DOI: 10.1128/Iai.02100-14  1
2014 Panas MW, Jain P, Yang H, Mitra S, Biswas D, Wattam AR, Letvin NL, Jacobs WR. Noncanonical SMC protein in Mycobacterium smegmatis restricts maintenance of Mycobacterium fortuitum plasmids. Proceedings of the National Academy of Sciences of the United States of America. 111: 13264-71. PMID 25197070 DOI: 10.1073/Pnas.1414207111  1
2014 Sixsmith JD, Panas MW, Lee S, Gillard GO, White K, Lifton MA, Balachandran H, Mach L, Miller JP, Lavine C, DeMarco CT, Tomaras GD, Gee C, Porcelli SA, Larsen MH, ... ... Letvin NL, et al. Recombinant Mycobacterium bovis bacillus Calmette-Guérin vectors prime for strong cellular responses to simian immunodeficiency virus gag in rhesus macaques. Clinical and Vaccine Immunology : Cvi. 21: 1385-95. PMID 25080550 DOI: 10.1128/Cvi.00324-14  1
2014 Pegu A, Yang ZY, Boyington JC, Wu L, Ko SY, Schmidt SD, McKee K, Kong WP, Shi W, Chen X, Todd JP, Letvin NL, Huang J, Nason MC, Hoxie JA, et al. Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor. Science Translational Medicine. 6: 243ra88. PMID 24990883 DOI: 10.1126/Scitranslmed.3008992  1
2014 Panas MW, Letvin NL. Role for Gr-1+ cells in the control of high-dose Mycobacterium bovis recombinant BCG. Clinical and Vaccine Immunology : Cvi. 21: 1120-7. PMID 24920602 DOI: 10.1128/Cvi.00363-14  1
2014 Giorgi EE, Balachandran H, Muldoon M, Letvin NL, Haynes BF, Korber BT, Santra S. Cross-reactive potential of human T-lymphocyte responses in HIV-1 infection. Vaccine. 32: 3995-4000. PMID 24837783 DOI: 10.1016/J.Vaccine.2014.04.040  1
2014 Osuna CE, Gonzalez AM, Chang HH, Hung AS, Ehlinger E, Anasti K, Alam SM, Letvin NL. TCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeys. Plos Pathogens. 10: e1004069. PMID 24743648 DOI: 10.1371/journal.ppat.1004069  1
2014 Moody MA, Santra S, Vandergrift NA, Sutherland LL, Gurley TC, Drinker MS, Allen AA, Xia SM, Meyerhoff RR, Parks R, Lloyd KE, Easterhoff D, Alam SM, Liao HX, Ward BM, ... ... Letvin NL, et al. Toll-like receptor 7/8 (TLR7/8) and TLR9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques. Journal of Virology. 88: 3329-39. PMID 24390332 DOI: 10.1128/Jvi.03309-13  1
2014 Roederer M, Keele BF, Schmidt SD, Mason RD, Welles HC, Fischer W, Labranche C, Foulds KE, Louder MK, Yang ZY, Todd JP, Buzby AP, Mach LV, Shen L, Seaton KE, ... ... Letvin NL, et al. Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV. Nature. 505: 502-8. PMID 24352234 DOI: 10.1038/Nature12893  1
2014 McGee K, Haim H, Korioth-Schmitz B, Espy N, Javanbakht H, Letvin N, Sodroski J. The selection of low envelope glycoprotein reactivity to soluble CD4 and cold during simian-human immunodeficiency virus infection of rhesus macaques. Journal of Virology. 88: 21-40. PMID 24131720 DOI: 10.1128/Jvi.01558-13  1
2013 Asmal M, Letvin NL, Geiben-Lynn R. Natural Killer cell-dependent and non-dependent anti-viral activity of 2-Cys Peroxiredoxin against HIV. International Trends in Immunity. 1: 69-77. PMID 24244928  1
2013 Kolodkin-Gal D, Hulot SL, Korioth-Schmitz B, Gombos RB, Zheng Y, Owuor J, Lifton MA, Ayeni C, Najarian RM, Yeh WW, Asmal M, Zamir G, Letvin NL. Efficiency of cell-free and cell-associated virus in mucosal transmission of human immunodeficiency virus type 1 and simian immunodeficiency virus. Journal of Virology. 87: 13589-97. PMID 24109227 DOI: 10.1128/Jvi.03108-12  1
2013 Chen CY, Yao S, Huang D, Wei H, Sicard H, Zeng G, Jomaa H, Larsen MH, Jacobs WR, Wang R, Letvin N, Shen Y, Qiu L, Shen L, Chen ZW. Phosphoantigen/IL2 expansion and differentiation of Vγ2Vδ2 T cells increase resistance to tuberculosis in nonhuman primates. Plos Pathogens. 9: e1003501. PMID 23966854 DOI: 10.1371/Journal.Ppat.1003501  1
2013 Fouda GG, Amos JD, Wilks AB, Pollara J, Ray CA, Chand A, Kunz EL, Liebl BE, Whitaker K, Carville A, Smith S, Colvin L, Pickup DJ, Staats HF, Overman G, ... ... Letvin NL, et al. Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk. Journal of Virology. 87: 6986-99. PMID 23596289 DOI: 10.1128/Jvi.00528-13  1
2013 Frencher JT, Ryan-Pasyeur BK, Huang D, Wang RC, McMullen PD, Letvin NL, Collins WE, Freitag NE, Malkovsky M, Chen CY, Shen L, Chen ZW. SHIV antigen immunization alters patterns of immune responses to SHIV/malaria coinfection and protects against life-threatening SHIV-related malaria. The Journal of Infectious Diseases. 208: 260-70. PMID 23568175 DOI: 10.1093/Infdis/Jit151  1
2013 Hellmann I, Letvin NL, Schmitz JE. KIR2DL4 copy number variation is associated with CD4+ T-cell depletion and function of cytokine-producing NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques. Journal of Virology. 87: 5305-10. PMID 23449795 DOI: 10.1128/JVI.02949-12  1
2013 Liao HX, Bonsignori M, Alam SM, McLellan JS, Tomaras GD, Moody MA, Kozink DM, Hwang KK, Chen X, Tsao CY, Liu P, Lu X, Parks RJ, Montefiori DC, Ferrari G, ... ... Letvin NL, et al. Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2. Immunity. 38: 176-86. PMID 23313589 DOI: 10.1016/J.Immuni.2012.11.011  1
2013 Alam SM, Liao HX, Tomaras GD, Bonsignori M, Tsao CY, Hwang KK, Chen H, Lloyd KE, Bowman C, Sutherland L, Jeffries TL, Kozink DM, Stewart S, Anasti K, Jaeger FH, ... ... Letvin NL, et al. Antigenicity and immunogenicity of RV144 vaccine AIDSVAX clade E envelope immunogen is enhanced by a gp120 N-terminal deletion. Journal of Virology. 87: 1554-68. PMID 23175357 DOI: 10.1128/Jvi.00718-12  1
2013 Bivas-Benita M, Gillard GO, Bar L, White KA, Webby RJ, Hovav AH, Letvin NL. Airway CD8(+) T cells induced by pulmonary DNA immunization mediate protective anti-viral immunity. Mucosal Immunology. 6: 156-66. PMID 22806099 DOI: 10.1038/mi.2012.59  1
2013 Sircar P, Furr KL, Letvin NL. Systemic vaccination induces clonally diverse SIV-specific CD8+ T-cell populations in systemic and mucosal compartments Mucosal Immunology. 6: 93-103. PMID 22763409 DOI: 10.1038/mi.2012.52  1
2012 Asmal M, Whitney JB, Luedemann C, Carville A, Steen R, Letvin NL, Geiben-Lynn R. In vivo anti-HIV activity of the heparin-activated serine protease inhibitor antithrombin III encapsulated in lymph-targeting immunoliposomes. Plos One. 7: e48234. PMID 23133620 DOI: 10.1371/Journal.Pone.0048234  1
2012 Fischer W, Apetrei C, Santiago ML, Li Y, Gautam R, Pandrea I, Shaw GM, Hahn BH, Letvin NL, Nabel GJ, Korber BT. Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages. Journal of Virology. 86: 13217-31. PMID 23055550 DOI: 10.1128/Jvi.01862-12  1
2012 Asmal M, Seaman M, Lin W, Chung RT, Letvin NL, Geiben-Lynn R. Inhibition of HCV by the serpin antithrombin III. Virology Journal. 9: 226. PMID 23031791 DOI: 10.1186/1743-422X-9-226  1
2012 Hellmann I, Schmitz JE, Letvin NL. Activating KIR copy number variation is associated with granzyme B release by NK cells during primary simian immunodeficiency virus infection in rhesus monkeys. Journal of Virology. 86: 13103-7. PMID 23015705 DOI: 10.1128/JVI.00325-12  1
2012 Grant EV, Thomas M, Fortune J, Klibanov AM, Letvin NL. Enhancement of plasmid DNA immunogenicity with linear polyethylenimine. European Journal of Immunology. 42: 2937-48. PMID 22886924 DOI: 10.1002/Eji.201242410  1
2012 Bolton DL, Santra S, Swett-Tapia C, Custers J, Song K, Balachandran H, Mach L, Naim H, Kozlowski PA, Lifton M, Goudsmit J, Letvin N, Roederer M, Radoševi? K. Priming T-cell responses with recombinant measles vaccine vector in a heterologous prime-boost setting in non-human primates. Vaccine. 30: 5991-8. PMID 22732429 DOI: 10.1016/J.Vaccine.2012.06.029  1
2012 Chang HH, Soderberg K, Skinner JA, Banchereau J, Chaussabel D, Haynes BF, Ramoni M, Letvin NL. Transcriptional network predicts viral set point during acute HIV-1 infection. Journal of the American Medical Informatics Association : Jamia. 19: 1103-9. PMID 22700869 DOI: 10.1136/Amiajnl-2012-000867  1
2012 Flatz L, Cheng C, Wang L, Foulds KE, Ko SY, Kong WP, Roychoudhuri R, Shi W, Bao S, Todd JP, Asmal M, Shen L, Donaldson M, Schmidt SD, Gall JG, ... ... Letvin NL, et al. Gene-based vaccination with a mismatched envelope protects against simian immunodeficiency virus infection in nonhuman primates. Journal of Virology. 86: 7760-70. PMID 22593152 DOI: 10.1128/Jvi.00599-12  1
2012 Yeh WW, Brassard LM, Miller CA, Basavapathruni A, Zhang J, Rao SS, Nabel GJ, Mascola JR, Letvin NL, Seaman MS. Envelope variable region 4 is the first target of neutralizing antibodies in early simian immunodeficiency virus mac251 infection of rhesus monkeys. Journal of Virology. 86: 7052-9. PMID 22532675 DOI: 10.1128/Jvi.00107-12  1
2012 Santra S, Muldoon M, Watson S, Buzby A, Balachandran H, Carlson KR, Mach L, Kong WP, McKee K, Yang ZY, Rao SS, Mascola JR, Nabel GJ, Korber BT, Letvin NL. Breadth of cellular and humoral immune responses elicited in rhesus monkeys by multi-valent mosaic and consensus immunogens. Virology. 428: 121-7. PMID 22521913 DOI: 10.1016/J.Virol.2012.03.012  1
2012 Yamamoto T, Johnson MJ, Price DA, Wolinsky DI, Almeida JR, Petrovas C, Nason M, Yeh WW, Shen L, Roederer M, Rao SS, McDermott AB, Lefebvre F, Nabel GJ, Haddad EK, ... Letvin NL, et al. Virus inhibition activity of effector memory CD8(+) T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection. Journal of Virology. 86: 5877-84. PMID 22419810 DOI: 10.1128/Jvi.00315-12  1
2011 Hellmann I, Lim SY, Gelman RS, Letvin NL. Association of activating KIR copy number variation of NK cells with containment of SIV replication in rhesus monkeys. Plos Pathogens. 7: e1002436. PMID 22194686 DOI: 10.1371/journal.ppat.1002436  1
2011 Dennison SM, Sutherland LL, Jaeger FH, Anasti KM, Parks R, Stewart S, Bowman C, Xia SM, Zhang R, Shen X, Scearce RM, Ofek G, Yang Y, Kwong PD, Santra S, ... ... Letvin NL, et al. Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41. Plos One. 6: e27824. PMID 22140469 DOI: 10.1371/journal.pone.0027824  1
2011 Pelak K, Need AC, Fellay J, Shianna KV, Feng S, Urban TJ, Ge D, De Luca A, Martinez-Picado J, Wolinsky SM, Martinson JJ, Jamieson BD, Bream JH, Martin MP, Borrow P, ... Letvin NL, et al. Copy number variation of KIR genes influences HIV-1 control. Plos Biology. 9: e1001208. PMID 22140359 DOI: 10.1371/Journal.Pbio.1001208  1
2011 Gnanakaran S, Bhattacharya T, Daniels M, Keele BF, Hraber PT, Lapedes AS, Shen T, Gaschen B, Krishnamoorthy M, Li H, Decker JM, Salazar-Gonzalez JF, Wang S, Jiang C, Gao F, ... ... Letvin NL, et al. Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections. Plos Pathogens. 7: e1002209. PMID 21980282 DOI: 10.1371/Journal.Ppat.1002209  1
2011 Ma BJ, Alam SM, Go EP, Lu X, Desaire H, Tomaras GD, Bowman C, Sutherland LL, Scearce RM, Santra S, Letvin NL, Kepler TB, Liao HX, Haynes BF. Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies. Plos Pathogens. 7: e1002200. PMID 21909262 DOI: 10.1371/Journal.Ppat.1002200  1
2011 Jackson SS, Schmitz JE, Letvin NL. Anti-gamma interferon antibodies enhance the immunogenicity of recombinant adenovirus vectors. Clinical and Vaccine Immunology : Cvi. 18: 1969-78. PMID 21900534 DOI: 10.1128/CVI.05180-11  1
2011 Mahlokozera T, Kang HH, Goonetilleke N, Stacey AR, Lovingood RV, Denny TN, Kalilani L, Bunn JE, Meshnick SR, Borrow P, Letvin NL, Permar SR. The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk. Plos One. 6: e23735. PMID 21886819 DOI: 10.1371/Journal.Pone.0023735  1
2011 Asmal M, Hellmann I, Liu W, Keele BF, Perelson AS, Bhattacharya T, Gnanakaran S, Daniels M, Haynes BF, Korber BT, Hahn BH, Shaw GM, Letvin NL. A signature in HIV-1 envelope leader peptide associated with transition from acute to chronic infection impacts envelope processing and infectivity. Plos One. 6: e23673. PMID 21876761 DOI: 10.1371/Journal.Pone.0023673  1
2011 Cale EM, Bazick HS, Rianprakaisang TA, Alam SM, Letvin NL. Mutations in a dominant Nef epitope of simian immunodeficiency virus diminish TCR:epitope peptide affinity but not epitope peptide:MHC class I binding. Journal of Immunology (Baltimore, Md. : 1950). 187: 3300-13. PMID 21841125 DOI: 10.4049/Jimmunol.1101080  1
2011 Gillard GO, Bivas-Benita M, Hovav AH, Grandpre LE, Panas MW, Seaman MS, Haynes BF, Letvin NL. Thy1+ NK [corrected] cells from vaccinia virus-primed mice confer protection against vaccinia virus challenge in the absence of adaptive lymphocytes. Plos Pathogens. 7: e1002141. PMID 21829360 DOI: 10.1371/Journal.Ppat.1002141  1
2011 Yeh WW, Rao SS, Lim SY, Zhang J, Hraber PT, Brassard LM, Luedemann C, Todd JP, Dodson A, Shen L, Buzby AP, Whitney JB, Korber BT, Nabel GJ, Mascola JR, ... Letvin NL, et al. The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys. Journal of Virology. 85: 10389-98. PMID 21775457 DOI: 10.1128/Jvi.00854-11  1
2011 Fouda GG, Yates NL, Pollara J, Shen X, Overman GR, Mahlokozera T, Wilks AB, Kang HH, Salazar-Gonzalez JF, Salazar MG, Kalilani L, Meshnick SR, Hahn BH, Shaw GM, Lovingood RV, ... ... Letvin NL, et al. HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies. Journal of Virology. 85: 9555-67. PMID 21734046 DOI: 10.1128/Jvi.05174-11  1
2011 Sun Y, Asmal M, Lane S, Permar SR, Schmidt SD, Mascola JR, Letvin NL. Antibody-dependent cell-mediated cytotoxicity in simian immunodeficiency virus-infected rhesus monkeys. Journal of Virology. 85: 6906-12. PMID 21593181 DOI: 10.1128/Jvi.00326-11  1
2011 Letvin NL, Rao SS, Montefiori DC, Seaman MS, Sun Y, Lim SY, Yeh WW, Asmal M, Gelman RS, Shen L, Whitney JB, Seoighe C, Lacerda M, Keating S, Norris PJ, et al. Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. Science Translational Medicine. 3: 81ra36. PMID 21543722 DOI: 10.1126/Scitranslmed.3002351  1
2011 Hulot SL, Cale EM, Korber BT, Letvin NL. Vaccine-induced CD8+ T lymphocytes of rhesus monkeys recognize variant forms of an HIV epitope but do not mediate optimal functional activity. Journal of Immunology (Baltimore, Md. : 1950). 186: 5663-74. PMID 21490161 DOI: 10.4049/Jimmunol.1100287  1
2011 Asmal M, Sun Y, Lane S, Yeh W, Schmidt SD, Mascola JR, Letvin NL. Antibody-dependent cell-mediated viral inhibition emerges after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys coincident with gp140-binding antibodies and is effective against neutralization-resistant viruses. Journal of Virology. 85: 5465-75. PMID 21450829 DOI: 10.1128/Jvi.00313-11  1
2011 Whitney JB, Hraber PT, Luedemann C, Giorgi EE, Daniels MG, Bhattacharya T, Rao SS, Mascola JR, Nabel GJ, Korber BT, Letvin NL. Genital tract sequestration of SIV following acute infection. Plos Pathogens. 7: e1001293. PMID 21379569 DOI: 10.1371/Journal.Ppat.1001293  1
2011 Geiben-Lynn R, Frimpong-Boateng K, Letvin NL. Modulation of plasmid DNA vaccine antigen clearance by caspase 12 RNA interference potentiates vaccination. Clinical and Vaccine Immunology : Cvi. 18: 533-8. PMID 21325489 DOI: 10.1128/CVI.00390-10  1
2011 Cale EM, Hraber P, Giorgi EE, Fischer W, Bhattacharya T, Leitner T, Yeh WW, Gleasner C, Green LD, Han CS, Korber B, Letvin NL. Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection. Journal of Virology. 85: 3746-57. PMID 21307185 DOI: 10.1128/Jvi.02420-10  1
2011 Qiu J, Yan L, Chen J, Chen CY, Shen L, Letvin NL, Haynes BF, Freitag N, Rong L, Frencher JT, Huang D, Wang X, Chen ZW. Intranasal vaccination with the recombinant Listeria monocytogenes ΔactA prfA* mutant elicits robust systemic and pulmonary cellular responses and secretory mucosal IgA. Clinical and Vaccine Immunology : Cvi. 18: 640-6. PMID 21270282 DOI: 10.1128/CVI.00254-10  1
2011 Salazar-Gonzalez JF, Salazar MG, Learn GH, Fouda GG, Kang HH, Mahlokozera T, Wilks AB, Lovingood RV, Stacey A, Kalilani L, Meshnick SR, Borrow P, Montefiori DC, Denny TN, Letvin NL, et al. Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing. Journal of Virology. 85: 2751-63. PMID 21191008 DOI: 10.1128/Jvi.02316-10  1
2011 Petrovski S, Fellay J, Shianna KV, Carpenetti N, Kumwenda J, Kamanga G, Kamwendo DD, Letvin NL, McMichael AJ, Haynes BF, Cohen MS, Goldstein DB. Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population. Aids (London, England). 25: 513-8. PMID 21160409 DOI: 10.1097/Qad.0B013E328343817B  1
2011 Yu JS, Whitesides J, Lee SH, Taylor N, Jacobs WR, Letvin NL, Haynes BF. Flow cytometry sorting of recombinant mycobacterial species yields bacterial clones with enhanced insert expression. Clinical and Vaccine Immunology : Cvi. 18: 43-9. PMID 21068210 DOI: 10.1128/Cvi.00292-10  1
2011 Yeh W, Rao S, Lim S, Zhang J, Hraber P, Brassard L, Luedemann C, Todd JP, Dodson A, Shen L, Buzby A, Whitney J, Korber B, Nabel G, Mascola J, ... Letvin N, et al. TRIM5 modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys F1000research. 2. DOI: 10.7490/F1000Research.1089571.1  1
2010 Barker BR, Gladstone MN, Gillard GO, Panas MW, Letvin NL. Critical role for IL-21 in both primary and memory anti-viral CD8+ T-cell responses. European Journal of Immunology. 40: 3085-96. PMID 21061439 DOI: 10.1002/Eji.200939939  1
2010 Wilks AB, Christian EC, Seaman MS, Sircar P, Carville A, Gomez CE, Esteban M, Pantaleo G, Barouch DH, Letvin NL, Permar SR. Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 185: 7097-106. PMID 21041730 DOI: 10.4049/Jimmunol.1002751  1
2010 Manuel ER, Yeh WW, Balachandran H, Clarke RH, Lifton MA, Letvin NL. Vaccination reduces simian-human immunodeficiency virus sequence reversion through enhanced viral control. Journal of Virology. 84: 12782-9. PMID 20881040 DOI: 10.1128/Jvi.01193-10  1
2010 Liu J, Keele BF, Li H, Keating S, Norris PJ, Carville A, Mansfield KG, Tomaras GD, Haynes BF, Kolodkin-Gal D, Letvin NL, Hahn BH, Shaw GM, Barouch DH. Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. Journal of Virology. 84: 10406-12. PMID 20686016 DOI: 10.1128/Jvi.01155-10  1
2010 Sun Y, Santra S, Buzby AP, Mascola JR, Nabel GJ, Letvin NL. Recombinant vector-induced HIV/SIV-specific CD4+ T lymphocyte responses in rhesus monkeys. Virology. 406: 48-55. PMID 20667574 DOI: 10.1016/J.Virol.2010.07.004  1
2010 Sircar P, Furr KL, Dorosh LA, Letvin NL. Clonal repertoires of virus-specific CD8+ T lymphocytes are shared in mucosal and systemic compartments during chronic simian immunodeficiency virus infection in rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 185: 2191-9. PMID 20624939 DOI: 10.4049/jimmunol.1001340  1
2010 Lim SY, Chan T, Gelman RS, Whitney JB, O'Brien KL, Barouch DH, Goldstein DB, Haynes BF, Letvin NL. Contributions of Mamu-A*01 status and TRIM5 allele expression, but not CCL3L copy number variation, to the control of SIVmac251 replication in Indian-origin rhesus monkeys. Plos Genetics. 6: e1000997. PMID 20585621 DOI: 10.1371/Journal.Pgen.1000997  1
2010 Permar SR, Wilks AB, Ehlinger EP, Kang HH, Mahlokozera T, Coffey RT, Carville A, Letvin NL, Seaman MS. Limited contribution of mucosal IgA to Simian immunodeficiency virus (SIV)-specific neutralizing antibody response and virus envelope evolution in breast milk of SIV-infected, lactating rhesus monkeys. Journal of Virology. 84: 8209-18. PMID 20519381 DOI: 10.1128/Jvi.00656-10  1
2010 Rogers TF, Lim SY, Sundsvold TJ, Chan T, Hsu A, Letvin NL. Variability in a dominant block to SIV early reverse transcription in rhesus monkey cells predicts in vivo viral replication and time to death. Virology Journal. 7: 79. PMID 20416115 DOI: 10.1186/1743-422X-7-79  1
2010 Yeh WW, Rahman I, Hraber P, Coffey RT, Nevidomskyte D, Giri A, Asmal M, Miljkovic S, Daniels M, Whitney JB, Keele BF, Hahn BH, Korber BT, Shaw GM, Seaman MS, ... Letvin NL, et al. Autologous neutralizing antibodies to the transmitted/founder viruses emerge late after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys. Journal of Virology. 84: 6018-32. PMID 20357097 DOI: 10.1128/Jvi.02741-09  1
2010 Bivas-Benita M, Bar L, Gillard GO, Kaufman DR, Simmons NL, Hovav AH, Letvin NL. Efficient generation of mucosal and systemic antigen-specific CD8+ T-cell responses following pulmonary DNA immunization. Journal of Virology. 84: 5764-74. PMID 20335249 DOI: 10.1128/JVI.02202-09  1
2010 Santra S, Liao HX, Zhang R, Muldoon M, Watson S, Fischer W, Theiler J, Szinger J, Balachandran H, Buzby A, Quinn D, Parks RJ, Tsao CY, Carville A, Mansfield KG, ... ... Letvin NL, et al. Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys. Nature Medicine. 16: 324-8. PMID 20173754 DOI: 10.1038/Nm.2108  1
2010 Zahn RC, Rett MD, Li M, Tang H, Korioth-Schmitz B, Balachandran H, White R, Pryputniewicz S, Letvin NL, Kaur A, Montefiori DC, Carville A, Hirsch VM, Allan JS, Schmitz JE. Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease. Blood. 115: 3070-8. PMID 20147699 DOI: 10.1182/Blood-2009-10-245225  1
2010 Permar SR, Kang HH, Wilks AB, Mach LV, Carville A, Mansfield KG, Learn GH, Hahn BH, Letvin NL. Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys. Retrovirology. 7: 7. PMID 20122164 DOI: 10.1186/1742-4690-7-7  1
2010 Lim SY, Rogers T, Chan T, Whitney JB, Kim J, Sodroski J, Letvin NL. TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys. Plos Pathogens. 6: e1000738. PMID 20107597 DOI: 10.1371/Journal.Ppat.1000738  1
2010 Permar SR, Kang HH, Carville A, Wilks AB, Mansfield KG, Rao SS, Letvin NL. Preservation of memory CD4(+) T lymphocytes in breast milk of lactating rhesus monkeys during acute simian immunodeficiency virus infection. The Journal of Infectious Diseases. 201: 302-10. PMID 20001855 DOI: 10.1086/649229  1
2010 Basavapathruni A, Yeh WW, Coffey RT, Whitney JB, Hraber PT, Giri A, Korber BT, Rao SS, Nabel GJ, Mascola JR, Seaman MS, Letvin NL. Envelope vaccination shapes viral envelope evolution following simian immunodeficiency virus infection in rhesus monkeys. Journal of Virology. 84: 953-63. PMID 19906933 DOI: 10.1128/Jvi.01679-09  1
2009 Fellay J, Ge D, Shianna KV, Colombo S, Ledergerber B, Cirulli ET, Urban TJ, Zhang K, Gumbs CE, Smith JP, Castagna A, Cozzi-Lepri A, De Luca A, Easterbrook P, Günthard HF, ... ... Letvin NL, et al. Common genetic variation and the control of HIV-1 in humans. Plos Genetics. 5: e1000791. PMID 20041166 DOI: 10.1371/Journal.Pgen.1000791  1
2009 Letvin NL. Virology. Moving forward in HIV vaccine development. Science (New York, N.Y.). 326: 1196-8. PMID 19965456 DOI: 10.1126/science.1183278  1
2009 Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, Letvin NL. Non-classical natural killer T cells modulate plasmid DNA vaccine antigen expression and vaccine-elicited immune responses by MCP-1 secretion after interaction with a beta2-microglobulin-independent CD1d. The Journal of Biological Chemistry. 284: 33800-6. PMID 19833737 DOI: 10.1074/Jbc.M109.019638  1
2009 Urban TJ, Weintrob AC, Fellay J, Colombo S, Shianna KV, Gumbs C, Rotger M, Pelak K, Dang KK, Detels R, Martinson JJ, O'Brien SJ, Letvin NL, McMichael AJ, Haynes BF, et al. CCL3L1 and HIV/AIDS susceptibility. Nature Medicine. 15: 1110-2. PMID 19812560 DOI: 10.1038/Nm1009-1110  1
2009 Letvin NL. A vaccine that delivers rather than induces antibodies Gene Therapy. 16: 1283-1284. PMID 19759565 DOI: 10.1038/gt.2009.121  1
2009 Hovav AH, Santosuosso M, Bivas-Benita M, Plair A, Cheng A, Elnekave M, Righi E, Chen T, Kashiwagi S, Panas MW, Xiang SH, Furmanov K, Letvin NL, Poznansky MC. X4 human immunodeficiency virus type 1 gp120 down-modulates expression and immunogenicity of codelivered antigens. Journal of Virology. 83: 10941-50. PMID 19692474 DOI: 10.1128/Jvi.00394-09  1
2009 Rodríguez A, Mintardjo R, Tax D, Gillissen G, Custers J, Pau MG, Klap J, Santra S, Balachandran H, Letvin NL, Goudsmit J, Radosevi? K. Evaluation of a prime-boost vaccine schedule with distinct adenovirus vectors against malaria in rhesus monkeys. Vaccine. 27: 6226-33. PMID 19686691 DOI: 10.1016/J.Vaccine.2009.07.106  1
2009 Santra S, Sun Y, Korioth-Schmitz B, Fitzgerald J, Charbonneau C, Santos G, Seaman MS, Ratcliffe SJ, Montefiori DC, Nabel GJ, Ertl HCJ, Letvin NL. Heterologous prime/boost immunizations of rhesus monkeys using chimpanzee adenovirus vectors Vaccine. 27: 5837-5845. PMID 19660588 DOI: 10.1016/J.Vaccine.2009.07.050  1
2009 Sun Y, Bailer RT, Rao SS, Mascola JR, Nabel GJ, Koup RA, Letvin NL. Systemic and mucosal T-lymphocyte activation induced by recombinant adenovirus vaccines in rhesus monkeys. Journal of Virology. 83: 10596-604. PMID 19656883 DOI: 10.1128/Jvi.01170-09  1
2009 Manuel ER, Yeh WW, Seaman MS, Furr K, Lifton MA, Hulot SL, Autissier P, Letvin NL. Dominant CD8+ T-lymphocyte responses suppress expansion of vaccine-elicited subdominant T lymphocytes in rhesus monkeys challenged with pathogenic simian-human immunodeficiency virus. Journal of Virology. 83: 10028-35. PMID 19641002 DOI: 10.1128/Jvi.01015-09  1
2009 Hulot SL, Seaman MS, Sen P, Autissier PA, Manuel ER, Letvin NL. Diverse cross-reactive potential and Vbeta gene usage of an epitope-specific cytotoxic T-lymphocyte population in monkeys immunized with diverse human immunodeficiency virus type 1 Env immunogens. Journal of Virology. 83: 9803-12. PMID 19640988 DOI: 10.1128/Jvi.00776-09  1
2009 Whitney JB, Luedemann C, Hraber P, Rao SS, Mascola JR, Nabel GJ, Letvin NL. T-cell vaccination reduces simian immunodeficiency virus levels in semen. Journal of Virology. 83: 10840-3. PMID 19640980 DOI: 10.1128/Jvi.01202-09  1
2009 Whitney JB, Luedemann C, Bao S, Miura A, Rao SS, Mascola JR, Letvin NL. Monitoring HIV vaccine trial participants for primary infection: studies in the SIV/macaque model. Aids (London, England). 23: 1453-60. PMID 19550289 DOI: 10.1097/Qad.0B013E32832B43D9  1
2009 Larsen MH, Biermann K, Chen B, Hsu T, Sambandamurthy VK, Lackner AA, Aye PP, Didier P, Huang D, Shao L, Wei H, Letvin NL, Frothingham R, Haynes BF, Chen ZW, et al. Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates. Vaccine. 27: 4709-17. PMID 19500524 DOI: 10.1016/J.Vaccine.2009.05.050  1
2009 Goonetilleke N, Liu MK, Salazar-Gonzalez JF, Ferrari G, Giorgi E, Ganusov VV, Keele BF, Learn GH, Turnbull EL, Salazar MG, Weinhold KJ, Moore S, Letvin N, Haynes BF, et al. The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. The Journal of Experimental Medicine. 206: 1253-72. PMID 19487423 DOI: 10.1084/Jem.20090365  1
2009 Walley NM, Julg B, Dickson SP, Fellay J, Ge D, Walker BD, Carrington M, Cohen MS, de Bakker PI, Goldstein DB, Shianna KV, Haynes BF, Letvin NL, McMichael AJ, Michael NL, et al. The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression. Cell Host & Microbe. 5: 408-10; author reply. PMID 19454339 DOI: 10.1016/J.Chom.2009.04.011  1
2009 Korber BT, Letvin NL, Haynes BF. T-cell vaccine strategies for human immunodeficiency virus, the virus with a thousand faces. Journal of Virology. 83: 8300-14. PMID 19439471 DOI: 10.1128/Jvi.00114-09  1
2009 Keele BF, Li H, Learn GH, Hraber P, Giorgi EE, Grayson T, Sun C, Chen Y, Yeh WW, Letvin NL, Mascola JR, Nabel GJ, Haynes BF, Bhattacharya T, Perelson AS, et al. Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1. The Journal of Experimental Medicine. 206: 1117-34. PMID 19414559 DOI: 10.1084/Jem.20082831  1
2009 Chen CY, Huang D, Wang RC, Shen L, Zeng G, Yao S, Shen Y, Halliday L, Fortman J, McAllister M, Estep J, Hunt R, Vasconcelos D, Du G, Porcelli SA, ... ... Letvin NL, et al. A critical role for CD8 T cells in a nonhuman primate model of tuberculosis. Plos Pathogens. 5: e1000392. PMID 19381260 DOI: 10.1371/Journal.Ppat.1000392  1
2009 Cayabyab MJ, Korioth-Schmitz B, Sun Y, Carville A, Balachandran H, Miura A, Carlson KR, Buzby AP, Haynes BF, Jacobs WR, Letvin NL. Recombinant Mycobacterium bovis BCG prime-recombinant adenovirus boost vaccination in rhesus monkeys elicits robust polyfunctional simian immunodeficiency virus-specific T-cell responses. Journal of Virology. 83: 5505-13. PMID 19297477 DOI: 10.1128/Jvi.02544-08  1
2009 Grandpre LE, Duke-Cohan JS, Ewald BA, Devoy C, Barouch DH, Letvin NL, Reinherz EL, Baden LR, Dolin R, Seaman MS. Immunogenicity of recombinant Modified Vaccinia Ankara following a single or multi-dose vaccine regimen in rhesus monkeys. Vaccine. 27: 1549-56. PMID 19168105 DOI: 10.1016/j.vaccine.2009.01.010  1
2009 Yeh WW, Jaru-Ampornpan P, Nevidomskyte D, Asmal M, Rao SS, Buzby AP, Montefiori DC, Korber BT, Letvin NL. Partial protection of Simian immunodeficiency virus (SIV)-infected rhesus monkeys against superinfection with a heterologous SIV isolate. Journal of Virology. 83: 2686-96. PMID 19129440 DOI: 10.1128/Jvi.02237-08  1
2009 Kong WP, Wu L, Wallstrom TC, Fischer W, Yang ZY, Ko SY, Letvin NL, Haynes BF, Hahn BH, Korber B, Nabel GJ. Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination. Journal of Virology. 83: 2201-15. PMID 19109395 DOI: 10.1128/Jvi.02256-08  1
2009 Fischer W, Apetrei C, Hahn BH, Letvin NL, Nabel GJ, Korber BT. P20-21 LB. Gene-to-gene differences in evolutionary rate between HIV-1 and natural SIV from sooty mangabeys: Implications for vaccine tests in non-human primates Retrovirology. 6: P425. DOI: 10.1186/1742-4690-6-S3-P425  1
2009 Letvin N, Mascola J, Rao S, Buzby A, Roederer M, Hudgens M, Gilbert P, Seder R, Douek D, Koup R, Graham B, Nabel G. P19-57 LB. Gene-based vaccination protects against mucosal infection by a heterologous highly pathogenic SIV isolate in rhesus monkeys Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P421  1
2009 Hulot SL, Seaman MS, Dorosh LA, Korber BT, Letvin NL. P17-09. Immunization with a single HIV-1 envelope sequence can generate CD8+ T lymphocytes capable of recognizing multiple variant forms of envelope Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P291  1
2009 Yeh W, Rahman I, Hraber P, Giri A, Nevidomskyte D, Coffey R, Asmal M, Miljkovic S, Whitney J, Keele B, Shaw G, Korber B, Seaman, Letvin N. P03-07. Autologous neutralizing antibodies that select viral escape variants emerge late after SIV infection of rhesus monkeys. Retrovirology. 6: 24. DOI: 10.1186/1742-4690-6-S3-P24  1
2009 Yeh WW, Jaru-ampornpan P, Nevidomskyte D, Asmal M, Rao SS, Buzby AP, Montefiori DC, Korber BT, Letvin NL. Partial protection of simian immunodeficiency virus (SIV)-infected rhesus monkeys against superinfection with a heterologous SIV isolate (Journal of Virology (2009) 83, 6 (2686-2696)) Journal of Virology. 83: 5293. DOI: 10.1128/Jvi.00496-09  1
2008 Zahn RC, Rett MD, Korioth-Schmitz B, Sun Y, Buzby AP, Goldstein S, Brown CR, Byrum RA, Freeman GJ, Letvin NL, Hirsch VM, Schmitz JE. Simian immunodeficiency virus (SIV)-specific CD8+ T-cell responses in vervet African green monkeys chronically infected with SIVagm. Journal of Virology. 82: 11577-88. PMID 18829748 DOI: 10.1128/JVI.01779-08  1
2008 Qiu L, Huang D, Chen CY, Wang R, Shen L, Shen Y, Hunt R, Estep J, Haynes BF, Jacobs WR, Letvin N, Du G, Chen ZW. Severe tuberculosis induces unbalanced up-regulation of gene networks and overexpression of IL-22, MIP-1alpha, CCL27, IP-10, CCR4, CCR5, CXCR3, PD1, PDL2, IL-3, IFN-beta, TIM1, and TLR2 but low antigen-specific cellular responses. The Journal of Infectious Diseases. 198: 1514-9. PMID 18811584 DOI: 10.1086/592448  1
2008 Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, van Rooijen N, Hovav AH, Letvin NL. CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses. Blood. 112: 4585-90. PMID 18784371 DOI: 10.1182/Blood-2008-06-165803  1
2008 Permar SR, Kang HH, Carville A, Mansfield KG, Gelman RS, Rao SS, Whitney JB, Letvin NL. Potent simian immunodeficiency virus-specific cellular immune responses in the breast milk of simian immunodeficiency virus-infected, lactating rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 181: 3643-50. PMID 18714039 DOI: 10.4049/Jimmunol.181.5.3643  1
2008 Santra S, Korber BT, Muldoon M, Barouch DH, Nabel GJ, Gao F, Hahn BH, Haynes BF, Letvin NL. A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys. Proceedings of the National Academy of Sciences of the United States of America. 105: 10489-94. PMID 18650391 DOI: 10.1073/Pnas.0803352105  1
2008 Sun Y, Santra S, Schmitz JE, Roederer M, Letvin NL. Magnitude and quality of vaccine-elicited T-cell responses in the control of immunodeficiency virus replication in rhesus monkeys. Journal of Virology. 82: 8812-9. PMID 18579590 DOI: 10.1128/JVI.00204-08  1
2008 Choi EI, Reimann KA, Letvin NL. In vivo natural killer cell depletion during primary simian immunodeficiency virus infection in rhesus monkeys. Journal of Virology. 82: 6758-61. PMID 18434394 DOI: 10.1128/JVI.02277-07  1
2008 Kim EY, Veazey RS, Zahn R, McEvers KJ, Baumeister SH, Foster GJ, Rett MD, Newberg MH, Kuroda MJ, Rieber EP, Piatak M, Lifson JD, Letvin NL, Wolinsky SM, Schmitz JE. Contribution of CD8+ T cells to containment of viral replication and emergence of mutations in Mamu-A*01-restricted epitopes in Simian immunodeficiency virus-infected rhesus monkeys. Journal of Virology. 82: 5631-5. PMID 18367519 DOI: 10.1128/Jvi.02749-07  1
2008 Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, Letvin NL. Kinetics of recombinant adenovirus type 5, vaccinia virus, modified vaccinia ankara virus, and DNA antigen expression in vivo and the induction of memory T-lymphocyte responses. Clinical and Vaccine Immunology : Cvi. 15: 691-6. PMID 18272665 DOI: 10.1128/Cvi.00418-07  1
2008 Fischer W, Liao HX, Haynes BF, Letvin NL, Korber B. Coping with viral diversity in HIV vaccine design: a response to Nickle et al. Plos Computational Biology. 4: e15; author reply e2. PMID 18225944 DOI: 10.1371/Journal.Pcbi.0040015  1
2008 Choi EI, Wang R, Peterson L, Letvin NL, Reimann KA. Use of an anti-CD16 antibody for in vivo depletion of natural killer cells in rhesus macaques. Immunology. 124: 215-22. PMID 18201184 DOI: 10.1111/j.1365-2567.2007.02757.x  1
2008 Barnett SW, Srivastava IK, Kan E, Zhou F, Goodsell A, Cristillo AD, Ferrai MG, Weiss DE, Letvin NL, Montefiori D, Pal R, Vajdy M. Protection of macaques against vaginal SHIV challenge by systemic or mucosal and systemic vaccinations with HIV-envelope. Aids (London, England). 22: 339-48. PMID 18195560 DOI: 10.1097/QAD.0b013e3282f3ca57  1
2008 Sen P, Charini WA, Subbramanian RA, Manuel ER, Kuroda MJ, Autissier PA, Letvin NL. Clonal focusing of epitope-specific CD8+ T lymphocytes in rhesus monkeys following vaccination and simian-human immunodeficiency virus challenge. Journal of Virology. 82: 805-16. PMID 17977967 DOI: 10.1128/Jvi.01038-07  1
2008 Huang D, Shen Y, Qiu L, Chen CY, Shen L, Estep J, Hunt R, Vasconcelos D, Du G, Aye P, Lackner AA, Larsen MH, Jacobs WR, Haynes BF, Letvin NL, et al. Immune distribution and localization of phosphoantigen-specific Vgamma2Vdelta2 T cells in lymphoid and nonlymphoid tissues in Mycobacterium tuberculosis infection. Infection and Immunity. 76: 426-36. PMID 17923514 DOI: 10.1128/Iai.01008-07  1
2007 Permar SR, Rao SS, Sun Y, Bao S, Buzby AP, Kang HH, Letvin NL. Clinical measles after measles virus challenge in simian immunodeficiency virus-infected measles virus-vaccinated rhesus monkeys. The Journal of Infectious Diseases. 196: 1784-93. PMID 18190259 DOI: 10.1086/522967  1
2007 Gao F, Liao HX, Hahn BH, Letvin NL, Korber BT, Haynes BF. Centralized HIV-1 envelope immunogens and neutralizing antibodies. Current Hiv Research. 5: 572-7. PMID 18045113 DOI: 10.2174/157016207782418498  1
2007 Hovav AH, Panas MW, Rahman S, Sircar P, Gillard G, Cayabyab MJ, Letvin NL. Duration of antigen expression in vivo following DNA immunization modifies the magnitude, contraction, and secondary responses of CD8+ T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 179: 6725-33. PMID 17982062 DOI: 10.4049/Jimmunol.179.10.6725  1
2007 Letvin NL. Correlates of immune protection and the development of a human immunodeficiency virus vaccine. Immunity. 27: 366-9. PMID 17892845 DOI: 10.1016/j.immuni.2007.09.001  1
2007 Hovav AH, Panas MW, Osuna CE, Cayabyab MJ, Autissier P, Letvin NL. The impact of a boosting immunogen on the differentiation of secondary memory CD8+ T cells. Journal of Virology. 81: 12793-802. PMID 17881444 DOI: 10.1128/Jvi.01519-07  1
2007 Barker BR, Parvani JG, Meyer D, Hey AS, Skak K, Letvin NL. IL-21 induces apoptosis of antigen-specific CD8+ T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 179: 3596-603. PMID 17785794 DOI: 10.4049/Jimmunol.179.6.3596  1
2007 Letvin NL, Rao SS, Dang V, Buzby AP, Korioth-Schmitz B, Dombagoda D, Parvani JG, Clarke RH, Bar L, Carlson KR, Kozlowski PA, Hirsch VM, Mascola JR, Nabel GJ. No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys. Journal of Virology. 81: 12368-74. PMID 17686853 DOI: 10.1128/Jvi.00822-07  1
2007 Mo Y, Quanquin NM, Vecino WH, Ranganathan UD, Tesfa L, Bourn W, Derbyshire KM, Letvin NL, Jacobs WR, Fennelly GJ. Genetic alteration of Mycobacterium smegmatis to improve mycobacterium-mediated transfer of plasmid DNA into mammalian cells and DNA immunization. Infection and Immunity. 75: 4804-16. PMID 17664267 DOI: 10.1128/Iai.01877-06  1
2007 Qin L, Greenland JR, Moriya C, Cayabyab MJ, Letvin NL. Effects of type I interferons on the adjuvant properties of plasmid granulocyte-macrophage colony-stimulating factor in vivo. Journal of Virology. 81: 10606-13. PMID 17652387 DOI: 10.1128/Jvi.01000-07  1
2007 Fellay J, Shianna KV, Ge D, Colombo S, Ledergerber B, Weale M, Zhang K, Gumbs C, Castagna A, Cossarizza A, Cozzi-Lepri A, De Luca A, Easterbrook P, Francioli P, Mallal S, ... ... Letvin NL, et al. A whole-genome association study of major determinants for host control of HIV-1. Science (New York, N.Y.). 317: 944-7. PMID 17641165 DOI: 10.1126/science.1143767  1
2007 Seaman MS, Leblanc DF, Grandpre LE, Bartman MT, Montefiori DC, Letvin NL, Mascola JR. Standardized assessment of NAb responses elicited in rhesus monkeys immunized with single- or multi-clade HIV-1 envelope immunogens. Virology. 367: 175-86. PMID 17599382 DOI: 10.1016/j.virol.2007.05.024  1
2007 Santra S, Sun Y, Parvani JG, Philippon V, Wyand MS, Manson K, Gomez-Yafal A, Mazzara G, Panicali D, Markham PD, Montefiori DC, Letvin NL. Heterologous prime/boost immunization of rhesus monkeys by using diverse poxvirus vectors Journal of Virology. 81: 8563-8570. PMID 17553898 DOI: 10.1128/JVI.00744-07  1
2007 Sun Y, Permar SR, Buzby AP, Letvin NL. Memory CD4+ T-lymphocyte loss and dysfunction during primary simian immunodeficiency virus infection. Journal of Virology. 81: 8009-15. PMID 17522197 DOI: 10.1128/Jvi.00482-07  1
2007 Yu JS, Peacock JW, Jacobs WR, Frothingham R, Letvin NL, Liao HX, Haynes BF. Recombinant Mycobacterium bovis bacillus Calmette-Guerin elicits human immunodeficiency virus type 1 envelope-specific T lymphocytes at mucosal sites. Clinical and Vaccine Immunology : Cvi. 14: 886-93. PMID 17507541 DOI: 10.1128/Cvi.00407-06  1
2007 Greenland JR, Geiben R, Ghosh S, Pastor WA, Letvin NL. Plasmid DNA vaccine-elicited cellular immune responses limit in vivo vaccine antigen expression through Fas-mediated apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 178: 5652-8. PMID 17442948 DOI: 10.4049/Jimmunol.178.9.5652  1
2007 McCoy K, Tatsis N, Korioth-Schmitz B, Lasaro MO, Hensley SE, Lin SW, Li Y, Giles-Davis W, Cun A, Zhou D, Xiang Z, Letvin NL, Ertl HC. Effect of preexisting immunity to adenovirus human serotype 5 antigens on the immune responses of nonhuman primates to vaccine regimens based on human- or chimpanzee-derived adenovirus vectors. Journal of Virology. 81: 6594-604. PMID 17428852 DOI: 10.1128/Jvi.02497-06  1
2007 Greenland JR, Letvin NL. Chemical adjuvants for plasmid DNA vaccines. Vaccine. 25: 3731-41. PMID 17350735 DOI: 10.1016/J.Vaccine.2007.01.120  1
2007 Hasegawa A, Moriya C, Liu H, Charini WA, Vinet HC, Subbramanian RA, Sen P, Letvin NL, Kuroda MJ. Analysis of TCRalphabeta combinations used by simian immunodeficiency virus-specific CD8+ T cells in rhesus monkeys: implications for CTL immunodominance. Journal of Immunology (Baltimore, Md. : 1950). 178: 3409-17. PMID 17339435 DOI: 10.4049/Jimmunol.178.6.3409  1
2007 McKenna PM, Koser ML, Carlson KR, Montefiori DC, Letvin NL, Papaneri AB, Pomerantz RJ, Dietzschold B, Silvera P, McGettigan JP, Schnell MJ. Highly attenuated rabies virus-based vaccine vectors expressing simian-human immunodeficiency virus89.6P Env and simian immunodeficiency virusmac239 Gag are safe in rhesus macaques and protect from an AIDS-like disease. The Journal of Infectious Diseases. 195: 980-8. PMID 17330788 DOI: 10.1086/512243  1
2007 Demberg T, Florese RH, Heath MJ, Larsen K, Kalisz I, Kalyanaraman VS, Lee EM, Pal R, Venzon D, Grant R, Patterson LJ, Korioth-Schmitz B, Buzby A, Dombagoda D, Montefiori DC, ... Letvin NL, et al. A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques. Journal of Virology. 81: 3414-27. PMID 17229693 DOI: 10.1128/JVI.02453-06  1
2007 Fischer W, Perkins S, Theiler J, Bhattacharya T, Yusim K, Funkhouser R, Kuiken C, Haynes B, Letvin NL, Walker BD, Hahn BH, Korber BT. Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. Nature Medicine. 13: 100-6. PMID 17187074 DOI: 10.1038/Nm1461  1
2007 Huang D, Qiu L, Wang R, Lai X, Du G, Seghal P, Shen Y, Shao L, Halliday L, Fortman J, Shen L, Letvin NL, Chen ZW. Immune gene networks of mycobacterial vaccine-elicited cellular responses and immunity. The Journal of Infectious Diseases. 195: 55-69. PMID 17152009 DOI: 10.1086/509895  1
2007 Hovav AH, Cayabyab MJ, Panas MW, Santra S, Greenland J, Geiben R, Haynes BF, Jacobs WR, Letvin NL. Rapid memory CD8+ T-lymphocyte induction through priming with recombinant Mycobacterium smegmatis. Journal of Virology. 81: 74-83. PMID 17050608 DOI: 10.1128/Jvi.01269-06  1
2006 Letvin NL. Progress and obstacles in the development of an AIDS vaccine Nature Reviews Immunology. 6: 930-939. PMID 17124514 DOI: 10.1038/nri1959  1
2006 Manuel ER, Charini WA, Sen P, Peyerl FW, Kuroda MJ, Schmitz JE, Autissier P, Sheeter DA, Torbett BE, Letvin NL. Contribution of T-cell receptor repertoire breadth to the dominance of epitope-specific CD8+ T-lymphocyte responses. Journal of Virology. 80: 12032-40. PMID 17035327 DOI: 10.1128/Jvi.01479-06  1
2006 Yu JS, Peacock JW, Vanleeuwen S, Hsu T, Jacobs WR, Cayabyab MJ, Letvin NL, Frothingham R, Staats HF, Liao HX, Haynes BF. Generation of mucosal anti-human immunodeficiency virus type 1 T-cell responses by recombinant Mycobacterium smegmatis. Clinical and Vaccine Immunology : Cvi. 13: 1204-11. PMID 16943347 DOI: 10.1128/Cvi.00195-06  1
2006 Sun Y, Schmitz JE, Buzby AP, Barker BR, Rao SS, Xu L, Yang ZY, Mascola JR, Nabel GJ, Letvin NL. Virus-specific cellular immune correlates of survival in vaccinated monkeys after simian immunodeficiency virus challenge. Journal of Virology. 80: 10950-6. PMID 16943292 DOI: 10.1128/Jvi.01458-06  1
2006 LaBonte ML, McKay PF, Letvin NL. Evidence of NK cell dysfunction in SIV-infected rhesus monkeys: Impairment of cytokine secretion and NKG2C/C2 expression European Journal of Immunology. 36: 2424-2433. PMID 16906533 DOI: 10.1002/eji.200635901  1
2006 Yeh WW, Cale EM, Jaru-Ampornpan P, Lord CI, Peyerl FW, Letvin NL. Compensatory substitutions restore normal core assembly in simian immunodeficiency virus isolates with Gag epitope cytotoxic T-lymphocyte escape mutations. Journal of Virology. 80: 8168-77. PMID 16873273 DOI: 10.1128/Jvi.00068-06  1
2006 Margolin DH, Saunders EH, Bronfin B, de Rosa N, Axthelm MK, Goloubeva OG, Eapen S, Gelman RS, Letvin NL. Germinal center function in the spleen during simian HIV infection in rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 177: 1108-19. PMID 16818768 DOI: 10.4049/jimmunol.177.2.1108  1
2006 Weaver EA, Lu Z, Camacho ZT, Moukdar F, Liao HX, Ma BJ, Muldoon M, Theiler J, Nabel GJ, Letvin NL, Korber BT, Hahn BH, Haynes BF, Gao F. Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen. Journal of Virology. 80: 6745-56. PMID 16809280 DOI: 10.1128/Jvi.02484-05  1
2006 Letvin NL, Mascola JR, Sun Y, Gorgone DA, Buzby AP, Xu L, Yang ZY, Chakrabarti B, Rao SS, Schmitz JE, Montefiori DC, Barker BR, Bookstein FL, Nabel GJ. Preserved CD4+ central memory T cells and survival in vaccinated SIV-challenged monkeys. Science (New York, N.Y.). 312: 1530-3. PMID 16763152 DOI: 10.1126/Science.1124226  1
2006 Mattapallil JJ, Douek DC, Buckler-White A, Montefiori D, Letvin NL, Nabel GJ, Roederer M. Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge Journal of Experimental Medicine. 203: 1533-1541. PMID 16735692 DOI: 10.1084/Jem.20060657  1
2006 Subbramanian RA, Charini WA, Kuroda MJ, Seaman M, Chhay H, Lifton MA, Gorgone DA, Schmitz JE, Carville A, Letvin NL. Expansion after epitope peptide exposure in vitro predicts cytotoxic T lymphocyte epitope dominance hierarchy in lymphocytes of vaccinated mamu-a*01+ rhesus monkeys. Aids Research and Human Retroviruses. 22: 445-52. PMID 16706622 DOI: 10.1089/Aid.2006.22.445  1
2006 Acierno PM, Schmitz JE, Gorgone DA, Sun Y, Santra S, Seaman MS, Newberg MH, Mascola JR, Nabel GJ, Panicali D, Letvin NL. Preservation of functional virus-specific memory CD8+ T lymphocytes in vaccinated, simian human immunodeficiency virus-infected rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 176: 5338-45. PMID 16622001 DOI: 10.4049/Jimmunol.176.9.5338  1
2006 Permar SR, Griffin DE, Letvin NL. Immune containment and consequences of measles virus infection in healthy and immunocompromised individuals. Clinical and Vaccine Immunology : Cvi. 13: 437-43. PMID 16603610 DOI: 10.1128/Cvi.13.4.437-443.2006  1
2006 Pal R, Venzon D, Santra S, Kalyanaraman VS, Montefiori DC, Hocker L, Hudacik L, Rose N, Nacsa J, Edghill-Smith Y, Moniuszko M, Hel Z, Belyakov IM, Berzofsky JA, Parks RW, ... ... Letvin NL, et al. Systemic immunization with an ALVAC-HIV-1/protein boost vaccine strategy protects rhesus macaques from CD4+ T-cell loss and reduces both systemic and mucosal simian-human immunodeficiency virus SHIVKU2 RNA levels. Journal of Virology. 80: 3732-42. PMID 16571790 DOI: 10.1128/JVI.80.8.3732-3742.2006  1
2006 Xu R, Srivastava IK, Kuller L, Zarkikh I, Kraft Z, Fagrouch Z, Letvin NL, Heeney JL, Barnett SW, Stamatatos L. Immunization with HIV-1 SF162-derived Envelope gp140 proteins does not protect macaques from heterologous simian-human immunodeficiency virus SHIV89.6P infection. Virology. 349: 276-89. PMID 16527321 DOI: 10.1016/J.Virol.2006.01.043  1
2006 Cayabyab MJ, Hovav AH, Hsu T, Krivulka GR, Lifton MA, Gorgone DA, Fennelly GJ, Haynes BF, Jacobs WR, Letvin NL. Generation of CD8+ T-cell responses by a recombinant nonpathogenic Mycobacterium smegmatis vaccine vector expressing human immunodeficiency virus type 1 Env. Journal of Virology. 80: 1645-52. PMID 16439521 DOI: 10.1128/Jvi.80.4.1645-1652.2006  1
2006 Newberg MH, McEvers KJ, Gorgone DA, Lifton MA, Baumeister SHC, Veazey RS, Schmitz JE, Letvin NL. Immunodomination in the evolution of dominant epitope-specific CD8 + T lymphocyte responses in simian immunodeficiency virus-infected rhesus monkeys Journal of Immunology. 176: 319-328. PMID 16365424 DOI: 10.4049/jimmunol.176.1.319  1
2006 Rao SS, Gomez P, Mascola JR, Dang V, Krivulka GR, Yu F, Lord CI, Shen L, Bailer R, Nabel GJ, Letvin NL. Comparative evaluation of three different intramuscular delivery methods for DNA immunization in a nonhuman primate animal model. Vaccine. 24: 367-73. PMID 16194587 DOI: 10.1016/J.Vaccine.2005.07.072  1
2005 Jackson SS, Schmitz JE, Kuroda MJ, McKay PF, Sumida SM, Martin KL, Yu F, Lifton MA, Gorgone DA, Letvin NL. Evaluation of CD62L expression as a marker for vaccine-elicited memory cytotoxic T lymphocytes. Immunology. 116: 443-53. PMID 16313358 DOI: 10.1111/j.1365-2567.2005.02243.x  1
2005 Peyerl FW, Barouch DH, Bazick HS, Manuel E, Letvin NL. Use of molecular beacons for rapid, real-time, quantitative monitoring of cytotoxic T-lymphocyte epitope mutations in simian immunodeficiency virus. Journal of Clinical Microbiology. 43: 4773-9. PMID 16145140 DOI: 10.1128/Jcm.43.9.4773-4779.2005  1
2005 Barouch DH, Yang ZY, Kong WP, Korioth-Schmitz B, Sumida SM, Truitt DM, Kishko MG, Arthur JC, Miura A, Mascola JR, Letvin NL, Nabel GJ. A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates. Journal of Virology. 79: 8828-34. PMID 15994776 DOI: 10.1128/Jvi.79.14.8828-8834.2005  1
2005 Greenland JR, Liu H, Berry D, Anderson DG, Kim WK, Irvine DJ, Langer R, Letvin NL. Beta-amino ester polymers facilitate in vivo DNA transfection and adjuvant plasmid DNA immunization. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 164-70. PMID 15963932 DOI: 10.1016/J.Ymthe.2005.01.021  1
2005 Schmitz JE, Johnson RP, McClure HM, Manson KH, Wyand MS, Kuroda MJ, Lifton MA, Khunkhun RS, McEvers KJ, Gillis J, Piatak M, Lifson JD, Grosschupff G, Racz P, Tenner-Racz K, ... ... Letvin NL, et al. Effect of CD8+ lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239delta3-vaccinated rhesus macaques. Journal of Virology. 79: 8131-41. PMID 15956558 DOI: 10.1128/Jvi.79.13.8131-8141.2005  1
2005 Bielefeldt-Ohmann H, Barouch DH, Bakke AM, Bruce AG, Durning M, Grant R, Letvin NL, Ryan JT, Schmidt A, Thouless ME, Rose TM. Intestinal stromal tumors in a simian immunodeficiency virus-infected, simian retrovirus-2 negative rhesus macaque (Macaca mulatta). Veterinary Pathology. 42: 391-6. PMID 15872392 DOI: 10.1354/vp.42-3-391  1
2005 Jackson SS, Ilyinskii P, Philippon V, Gritz L, Yafal AG, Zinnack K, Beaudry KR, Manson KH, Lifton MA, Kuroda MJ, Letvin NL, Mazzara GP, Panicali DL. Role of genes that modulate host immune responses in the immunogenicity and pathogenicity of vaccinia virus. Journal of Virology. 79: 6554-9. PMID 15858042 DOI: 10.1128/JVI.79.10.6554-6559.2005  1
2005 Santra S, Seaman MS, Xu L, Barouch DH, Lord CI, Lifton MA, Gorgone DA, Beaudry KR, Svehla K, Welcher B, Chakrabarti BK, Huang Y, Yang ZY, Mascola JR, Nabel GJ, ... Letvin NL, et al. Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. Journal of Virology. 79: 6516-22. PMID 15858035 DOI: 10.1128/Jvi.79.10.6516-6522.2005  1
2005 Sun Y, Schmitz JE, Acierno PM, Santra S, Subbramanian RA, Barouch DH, Gorgone DA, Lifton MA, Beaudry KR, Manson K, Philippon V, Xu L, Maecker HT, Mascola JR, Panicali D, ... ... Letvin NL, et al. Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 174: 4753-60. PMID 15814700 DOI: 10.4049/Jimmunol.174.8.4753  1
2005 Seaman MS, Santra S, Newberg MH, Philippon V, Manson K, Xu L, Gelman RS, Panicali D, Mascola JR, Nabel GJ, Letvin NL. Vaccine-elicited memory cytotoxic T lymphocytes contribute to Mamu-A*01-associated control of simian/human immunodeficiency virus 89.6P replication in rhesus monkeys. Journal of Virology. 79: 4580-8. PMID 15795244 DOI: 10.1128/Jvi.79.8.4580-4588.2005  1
2005 Hershberger KL, Kurian J, Korber BT, Letvin NL. Killer cell immunoglobulin-like receptors (KIR) of the African-origin sabaeus monkey: evidence for recombination events in the evolution of KIR. European Journal of Immunology. 35: 922-35. PMID 15714591 DOI: 10.1002/Eji.200425408  1
2005 Seaman MS, Xu L, Beaudry K, Martin KL, Beddall MH, Miura A, Sambor A, Chakrabarti BK, Huang Y, Bailer R, Koup RA, Mascola JR, Nabel GJ, Letvin NL. Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys. Journal of Virology. 79: 2956-63. PMID 15709015 DOI: 10.1128/Jvi.79.5.2956-2963.2005  1
2005 Barouch DH, Powers J, Truitt DM, Kishko MG, Arthur JC, Peyerl FW, Kuroda MJ, Gorgone DA, Lifton MA, Lord CI, Hirsch VM, Montefiori DC, Carville A, Mansfield KG, Kunstman KJ, ... ... Letvin NL, et al. Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants. Nature Immunology. 6: 247-52. PMID 15685174 DOI: 10.1038/Ni1167  1
2005 Letvin NL. Progress toward an HIV vaccine Annual Review of Medicine. 56: 213-223. PMID 15660510 DOI: 10.1146/annurev.med.54.101601.152349  1
2005 Dang X, Axthelm MK, Letvin NL, Koralnik IJ. Rearrangement of simian virus 40 regulatory region is not required for induction of progressive multifocal leukoencephalopathy in immunosuppressed rhesus monkeys. Journal of Virology. 79: 1361-6. PMID 15650162 DOI: 10.1128/JVI.79.3.1361-1366.2005  1
2005 Johnson PR, Schnepp BC, Connell MJ, Rohne D, Robinson S, Krivulka GR, Lord CI, Zinn R, Montefiori DC, Letvin NL, Clark KR. Novel adeno-associated virus vector vaccine restricts replication of simian immunodeficiency virus in macaques. Journal of Virology. 79: 955-65. PMID 15613324 DOI: 10.1128/JVI.79.2.955-965.2005  1
2005 Mascola JR, Sambor A, Beaudry K, Santra S, Welcher B, Louder MK, Vancott TC, Huang Y, Chakrabarti BK, Kong WP, Yang ZY, Xu L, Montefiori DC, Nabel GJ, Letvin NL. Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins. Journal of Virology. 79: 771-9. PMID 15613305 DOI: 10.1128/Jvi.79.2.771-779.2005  1
2005 Barouch D, Letvin N, Havenga M, Goudsmit J. Novel Adenovirus Vector-Based Vaccines for HIV Retrovirology. 2: 1-1. DOI: 10.1186/1742-4690-2-S1-S60  0.01
2004 Price DA, West SM, Betts MR, Ruff LE, Brenchley JM, Ambrozak DR, Edghill-Smith Y, Kuroda MJ, Bogdan D, Kunstman K, Letvin NL, Franchini G, Wolinsky SM, Koup RA, Douek DC. T cell receptor recognition motifs govern immune escape patterns in acute SIV infection. Immunity. 21: 793-803. PMID 15589168 DOI: 10.1016/J.Immuni.2004.10.010  1
2004 Peyerl FW, Bazick HS, Newberg MH, Barouch DH, Sodroski J, Letvin NL. Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope. Journal of Virology. 78: 13901-10. PMID 15564498 DOI: 10.1128/Jvi.78.24.13901-13910.2004  1
2004 Barouch DH, Letvin NL, Seder RA. The role of cytokine DNAs as vaccine adjuvants for optimizing cellular immune responses Immunological Reviews. 202: 266-274. PMID 15546399 DOI: 10.1111/j.0105-2896.2004.00200.x  1
2004 Peacock JW, Nordone SK, Jackson SS, Liao HX, Letvin NL, Yafal AG, Gritz L, Mazzara GP, Haynes BF, Staats HF. Gender differences in human immunodeficiency virus type 1-specific CD8 responses in the reproductive tract and colon following nasal peptide priming and modified vaccinia virus Ankara boosting. Journal of Virology. 78: 13163-72. PMID 15542668 DOI: 10.1128/JVI.78.23.13163-13172.2004  1
2004 Sumida SM, McKay PF, Truitt DM, Kishko MG, Arthur JC, Seaman MS, Jackson SS, Gorgone DA, Lifton MA, Letvin NL, Barouch DH. Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines. The Journal of Clinical Investigation. 114: 1334-42. PMID 15520866 DOI: 10.1172/Jci22608  1
2004 Subbramanian RA, Moriya C, Martin KL, Peyerl FW, Hasegawa A, Naoi A, Chhay H, Autissier P, Gorgone DA, Lifton MA, Kuus-Reichel K, Schmitz JE, Letvin NL, Kuroda MJ. Engineered T-cell receptor tetramers bind MHC-peptide complexes with high affinity. Nature Biotechnology. 22: 1429-34. PMID 15502816 DOI: 10.1038/nbt1024  1
2004 Labonte ML, Letvin NL. Variable NKG2 expression in the peripheral blood lymphocytes of rhesus monkeys Clinical and Experimental Immunology. 138: 205-212. PMID 15498028 DOI: 10.1111/j.1365-2249.2004.02625.x  1
2004 Kim WK, Corey S, Chesney G, Knight H, Klumpp S, Wüthrich C, Letvin N, Koralnik I, Lackner A, Veasey R, Williams K. Identification of T lymphocytes in simian immunodeficiency virus encephalitis: distribution of CD8+ T cells in association with central nervous system vessels and virus. Journal of Neurovirology. 10: 315-25. PMID 15385254 DOI: 10.1080/13550280490505382  1
2004 Du Pasquier RA, Schmitz JE, Jean-Jacques J, Zheng Y, Gordon J, Khalili K, Letvin NL, Koralnik IJ. Detection of JC virus-specific cytotoxic T lymphocytes in healthy individuals. Journal of Virology. 78: 10206-10. PMID 15331755 DOI: 10.1128/Jvi.78.18.10206-10210.2004  1
2004 Barouch DH, Truitt DM, Letvin NL. Expression kinetics of the interleukin-2/immunoglobulin (IL-2/Ig) plasmid cytokine adjuvant Vaccine. 22: 3092-3097. PMID 15297060 DOI: 10.1016/j.vaccine.2004.01.065  1
2004 Permar SR, Klumpp SA, Mansfield KG, Carville AA, Gorgone DA, Lifton MA, Schmitz JE, Reimann KA, Polack FP, Griffin DE, Letvin NL. Limited contribution of humoral immunity to the clearance of measles viremia in rhesus monkeys. The Journal of Infectious Diseases. 190: 998-1005. PMID 15295708 DOI: 10.1086/422846  1
2004 Axthelm MK, Koralnik IJ, Dang X, Wüthrich C, Rohne D, Stillman IE, Letvin NL. Meningoencephalitis and demyelination are pathologic manifestations of primary polyomavirus infection in immunosuppressed rhesus monkeys. Journal of Neuropathology and Experimental Neurology. 63: 750-8. PMID 15290900  1
2004 Peyerl FW, Barouch DH, Letvin NL. Structural constraints on viral escape from HIV- and SIV-specific cytotoxic T-lymphocytes. Viral Immunology. 17: 144-51. PMID 15279695 DOI: 10.1089/0882824041310658  1
2004 Santra S, Barouch DH, Korioth-Schmitz B, Lord CI, Krivulka GR, Yu F, Beddall MH, Gorgone DA, Lifton MA, Miura A, Philippon V, Manson K, Markham PD, Parrish J, Kuroda MJ, ... ... Letvin NL, et al. Recombinant poxvirus boosting of DNA-primed rhesus monkeys augments peak but not memory T lymphocyte responses. Proceedings of the National Academy of Sciences of the United States of America. 101: 11088-93. PMID 15258286 DOI: 10.1073/Pnas.0401954101  1
2004 Barouch DH, Letvin NL. HIV escape from cytotoxic T lymphocytes: A potential hurdle for vaccines? Lancet. 364: 10-11. PMID 15234837 DOI: 10.1016/S0140-6736(04)16609-9  1
2004 Letvin NL, Huang Y, Chakrabarti BK, Xu L, Seaman MS, Beaudry K, Korioth-Schmitz B, Yu F, Rohne D, Martin KL, Miura A, Kong WP, Yang ZY, Gelman RS, Golubeva OG, et al. Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys. Journal of Virology. 78: 7490-7. PMID 15220422 DOI: 10.1128/Jvi.78.14.7490-7497.2004  1
2004 Du Pasquier RA, Kuroda MJ, Zheng Y, Jean-Jacques J, Letvin NL, Koralnik IJ. A prospective study demonstrates an association between JC virus-specific cytotoxic T lymphocytes and the early control of progressive multifocal leukoencephalopathy. Brain : a Journal of Neurology. 127: 1970-8. PMID 15215217 DOI: 10.1093/Brain/Awh215  1
2004 LaBonte ML, Choi EI, Letvin NL. Molecular determinants regulating the pairing of NKG2 molecules with CD94 for cell surface heterodimer expression Journal of Immunology. 172: 6902-6912. PMID 15153509  1
2004 Haigwood NL, Montefiori DC, Sutton WF, McClure J, Watson AJ, Voss G, Hirsch VM, Richardson BA, Letvin NL, Hu SL, Johnson PR. Passive immunotherapy in simian immunodeficiency virus-infected macaques accelerates the development of neutralizing antibodies. Journal of Virology. 78: 5983-95. PMID 15140996 DOI: 10.1128/Jvi.78.11.5983-5995.2004  1
2004 Barouch DH, Pau MG, Custers JH, Koudstaal W, Kostense S, Havenga MJ, Truitt DM, Sumida SM, Kishko MG, Arthur JC, Korioth-Schmitz B, Newberg MH, Gorgone DA, Lifton MA, Panicali DL, ... ... Letvin NL, et al. Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity. Journal of Immunology (Baltimore, Md. : 1950). 172: 6290-7. PMID 15128818 DOI: 10.4049/Jimmunol.172.10.6290  1
2004 Mattapallil JJ, Letvin NL, Roederer M. T-cell dynamics during acute SIV infection Aids. 18: 13-23. PMID 15090825 DOI: 10.1097/00002030-200401020-00002  1
2004 Song B, Cayabyab M, Phan N, Wang L, Axthelm MK, Letvin NL, Sodroski JG. Neutralization sensitivity of a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2N) isolated from an infected rhesus macaque with neurological disease. Virology. 322: 168-81. PMID 15063126 DOI: 10.1016/J.Virol.2004.02.001  1
2004 McKay PF, Barouch DH, Santra S, Sumida SM, Jackson SS, Gorgone DA, Lifton MA, Letvin NL. Recruitment of different subsets of antigen-presenting cells selectively modulates DNA vaccine-elicited CD4+ and CD8+ T lymphocyte responses European Journal of Immunology. 34: 1011-1020. PMID 15048711 DOI: 10.1002/eji.200324840  1
2004 Cayabyab M, Rohne D, Pollakis G, Mische C, Messele T, Abebe A, Etemad-Moghadam B, Yang P, Henson S, Axthelm M, Goudsmit J, Letvin NL, Sodroski J. Rapid CD4+ T-lymphocyte depletion in rhesus monkeys infected with a simian-human immunodeficiency virus expressing the envelope glycoproteins of a primary dual-tropic Ethiopian Clade C HIV type 1 isolate. Aids Research and Human Retroviruses. 20: 27-40. PMID 15000696 DOI: 10.1089/088922204322749477  1
2004 Sumida SM, Truitt DM, Kishko MG, Arthur JC, Jackson SS, Gorgone DA, Lifton MA, Koudstaal W, Pau MG, Kostense S, Havenga MJ, Goudsmit J, Letvin NL, Barouch DH. Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. Journal of Virology. 78: 2666-73. PMID 14990686 DOI: 10.1128/Jvi.78.6.2666-2673.2004  1
2004 Hirsch VM, Santra S, Goldstein S, Plishka R, Buckler-White A, Seth A, Ourmanov I, Brown CR, Engle R, Montefiori D, Glowczwskie J, Kunstman K, Wolinsky S, Letvin NL. Immune failure in the absence of profound CD4+ T-lymphocyte depletion in simian immunodeficiency virus-infected rapid progressor macaques. Journal of Virology. 78: 275-84. PMID 14671109 DOI: 10.1128/JVI.78.1.275-284.2004  1
2004 Seaman MS, Peyerl FW, Jackson SS, Lifton MA, Gorgone DA, Schmitz JE, Letvin NL. Subsets of memory cytotoxic T lymphocytes elicited by vaccination influence the efficiency of secondary expansion in vivo. Journal of Virology. 78: 206-15. PMID 14671102 DOI: 10.1128/JVI.78.1.206-215.2004  1
2004 Levinson G, Hughes AL, Letvin NL. Sequence and diversity of rhesus monkey T-cell receptor β chain genes Immunogenetics. 35: 75-88. PMID 1531206 DOI: 10.1007/BF00189516  1
2003 Peyerl FW, Barouch DH, Yeh WW, Bazick HS, Kunstman J, Kunstman KJ, Wolinsky SM, Letvin NL. Simian-human immunodeficiency virus escape from cytotoxic T-lymphocyte recognition at a structurally constrained epitope. Journal of Virology. 77: 12572-8. PMID 14610180 DOI: 10.1128/JVI.77.23.12572-12578.2003  1
2003 Gao F, Li Y, Decker JM, Peyerl FW, Bibollet-Ruche F, Rodenburg CM, Chen Y, Shaw DR, Allen S, Musonda R, Shaw GM, Zajac AJ, Letvin N, Hahn BH. Codon usage optimization of HIV type 1 subtype C gag, pol, env, and nef genes: in vitro expression and immune responses in DNA-vaccinated mice. Aids Research and Human Retroviruses. 19: 817-23. PMID 14585212 DOI: 10.1089/088922203769232610  1
2003 Du Pasquier RA, Kuroda MJ, Schmitz JE, Zheng Y, Martin K, Peyerl FW, Lifton M, Gorgone D, Autissier P, Letvin NL, Koralnik IJ. Low frequency of cytotoxic T lymphocytes against the novel HLA-A*0201-restricted JC virus epitope VP1(p36) in patients with proven or possible progressive multifocal leukoencephalopathy. Journal of Virology. 77: 11918-26. PMID 14581528 DOI: 10.1128/Jvi.77.22.11918-11926.2003  1
2003 Mascola JR, Lewis MG, VanCott TC, Stiegler G, Katinger H, Seaman M, Beaudry K, Barouch DH, Korioth-Schmitz B, Krivulka G, Sambor A, Welcher B, Douek DC, Montefiori DC, Shiver JW, ... ... Letvin NL, et al. Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies. Journal of Virology. 77: 10348-56. PMID 12970419 DOI: 10.1128/JVI.77.19.10348-10356.2003  1
2003 Subbramanian RA, Kuroda MJ, Charini WA, Barouch DH, Costantino C, Santra S, Schmitz JE, Martin KL, Lifton MA, Gorgone DA, Shiver JW, Letvin NL. Magnitude and diversity of cytotoxic-T-lymphocyte responses elicited by multiepitope DNA vaccination in rhesus monkeys. Journal of Virology. 77: 10113-8. PMID 12941922 DOI: 10.1128/JVI.77.18.10113-10118.2003  1
2003 Barouch DH, McKay PF, Sumida SM, Santra S, Jackson SS, Gorgone DA, Lifton MA, Chakrabarti BK, Xu L, Nabel GJ, Letvin NL. Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines. Journal of Virology. 77: 8729-35. PMID 12885892 DOI: 10.1128/Jvi.77.16.8729-8735.2003  1
2003 Letvin NL, Walker BD. Immunopathogenesis and immunotherapy in AIDS virus infections Nature Medicine. 9: 861-866. PMID 12835706 DOI: 10.1038/nm0703-861  1
2003 Barouch DH, Kunstman J, Glowczwskie J, Kunstman KJ, Egan MA, Peyerl FW, Santra S, Kuroda MJ, Schmitz JE, Beaudry K, Krivulka GR, Lifton MA, Gorgone DA, Wolinsky SM, Letvin NL. Viral escape from dominant simian immunodeficiency virus epitope-specific cytotoxic T lymphocytes in DNA-vaccinated rhesus monkeys. Journal of Virology. 77: 7367-75. PMID 12805435 DOI: 10.1128/JVI.77.13.7367-7375.2003  1
2003 Chen ZW, Letvin NL. Vγ2Vδ2+ T cells and anti-microbial immune responses Microbes and Infection. 5: 491-498. PMID 12758278 DOI: 10.1016/S1286-4579(03)00074-1  1
2003 Chen ZW, Letvin NL. Adaptive immune response of Vγ2Vδ2 T cells: A new paradigm Trends in Immunology. 24: 213-219. PMID 12697454 DOI: 10.1016/S1471-4906(03)00032-2  1
2003 Premenko-Lanier M, Rota PA, Rhodes G, Verhoeven D, Barouch DH, Lerche NW, Letvin NL, Bellini WJ, McChesney MB. DNA vaccination of infants in the presence of maternal antibody: a measles model in the primate. Virology. 307: 67-75. PMID 12667815 DOI: 10.1016/S0042-6822(02)00036-3  1
2003 McKay PF, Barouch DH, Schmitz JE, Veazey RS, Gorgone DA, Lifton MA, Williams KC, Letvin NL. Global dysfunction of CD4 T-lymphocyte cytokine expression in simian-human immunodeficiency virus/SIV-infected monkeys is prevented by vaccination Journal of Virology. 77: 4695-4702. PMID 12663776 DOI: 10.1128/JVI.77.8.4695-4702.2003  1
2003 Permar SR, Klumpp SA, Mansfield KG, Kim WK, Gorgone DA, Lifton MA, Williams KC, Schmitz JE, Reimann KA, Axthelm MK, Polack FP, Griffin DE, Letvin NL. Role of CD8(+) lymphocytes in control and clearance of measles virus infection of rhesus monkeys. Journal of Virology. 77: 4396-400. PMID 12634396 DOI: 10.1128/Jvi.77.7.4396-4400.2003  1
2003 Schmollinger JC, Vonderheide RH, Hoar KM, Maecker B, Schultze JL, Hodi FS, Soiffer RJ, Jung K, Kuroda MJ, Letvin NL, Greenfield EA, Mihm M, Kutok JL, Dranoff G. Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction. Proceedings of the National Academy of Sciences of the United States of America. 100: 3398-403. PMID 12626761 DOI: 10.1073/Pnas.0530311100  1
2003 Zhou D, Lai X, Shen Y, Sehgal P, Shen L, Simon M, Qiu L, Huang D, Du GZ, Wang Q, Letvin NL, Chen ZW. Inhibition of adaptive Vgamma2Vdelta2+ T-cell responses during active mycobacterial coinfection of simian immunodeficiency virus SIVmac-infected monkeys. Journal of Virology. 77: 2998-3006. PMID 12584325 DOI: 10.1128/JVI.77.5.2998-3006.2003  1
2003 Kempf W, Kadin ME, Dvorak AM, Lord CC, Burg G, Letvin NL, Koralnik IJ. Endogenous retroviral elements, but not exogenous retroviruses, are detected in CD30-positive lymphoproliferative disorders of the skin. Carcinogenesis. 24: 301-6. PMID 12584181 DOI: 10.1093/carcin/24.2.301  1
2003 Schmitz JE, Kuroda MJ, Santra S, Simon MA, Lifton MA, Lin W, Khunkhun R, Piatak M, Lifson JD, Grosschupff G, Gelman RS, Racz P, Tenner-Racz K, Mansfield KA, Letvin NL, et al. Effect of humoral immune responses on controlling viremia during primary infection of rhesus monkeys with simian immunodeficiency virus. Journal of Virology. 77: 2165-73. PMID 12525651 DOI: 10.1128/JVI.77.3.2165-2173.2003  1
2003 Choi EI, Letvin NL. AIDS Vaccines: Challenges and Prospects The Vaccine Book. 245-255. DOI: 10.1016/B978-012107258-2/50020-2  1
2002 Barouch DH, Letvin NL. Viral evolution and challenges in the development of HIV vaccines Vaccine. 20. PMID 12477431 DOI: 10.1016/S0264-410X(02)00390-0  1
2002 Baig J, Levy DB, McKay PF, Schmitz JE, Santra S, Subbramanian RA, Kuroda MJ, Lifton MA, Gorgone DA, Wyatt LS, Moss B, Huang Y, Chakrabarti BK, Xu L, Kong WP, ... ... Letvin NL, et al. Elicitation of simian immunodeficiency virus-specific cytotoxic T lymphocytes in mucosal compartments of rhesus monkeys by systemic vaccination. Journal of Virology. 76: 11484-90. PMID 12388710 DOI: 10.1128/Jvi.76.22.11484-11490.2002  1
2002 Newberg MH, Kuroda MJ, Charini WA, Miura A, Lord CI, Schmitz JE, Gorgone DA, Lifton MA, Kuus-Reichel K, Letvin NL. A simian immunodeficiency virus nef peptide is a dominant cytotoxic T lymphocyte epitope in Indian-origin rhesus monkeys expressing the common MHC class I allele mamu-A*02. Virology. 301: 365-73. PMID 12359438 DOI: 10.1006/viro.2002.1598  1
2002 Letvin NL. Strategies for an HIV vaccine Journal of Clinical Investigation. 110: 15-20. PMID 12093882 DOI: 10.1172/JCI200215985  1
2002 Santra S, Barouch DH, Kuroda MJ, Schmitz JE, Krivulka GR, Beaudry K, Lord CI, Lifton MA, Wyatt LS, Moss B, Hirsch VM, Letvin NL. Prior vaccination increases the epitopic breadth of the cytotoxic T-lymphocyte response that evolves in rhesus monkeys following a simian-human immunodeficiency virus infection. Journal of Virology. 76: 6376-81. PMID 12021371 DOI: 10.1128/Jvi.76.12.6376-6381.2002  1
2002 Etemad-Moghadam B, Rhone D, Steenbeke T, Sun Y, Manola J, Gelman R, Fanton JW, Racz P, Tenner-Racz K, Axthelm MK, Letvin NL, Sodroski J. Understanding the basis of CD4(+) T-cell depletion in macaques infected by a simian-human immunodeficiency virus. Vaccine. 20: 1934-7. PMID 11983249 DOI: 10.1016/S0264-410X(02)00072-5  1
2002 Rasmussen RA, Hofmann-Lehmann R, Li PL, Vlasak J, Schmitz JE, Reimann KA, Kuroda MJ, Letvin NL, Montefiori DC, McClure HM, Ruprecht RM. Neutralizing antibodies as a potential secondary protective mechanism during chronic SHIV infection in CD8+ T-cell-depleted macaques. Aids (London, England). 16: 829-38. PMID 11919484 DOI: 10.1097/00002030-200204120-00002  1
2002 Shen Y, Zhou D, Qiu L, Lai X, Simon M, Shen L, Kou Z, Wang Q, Jiang L, Estep J, Hunt R, Clagett M, Sehgal PK, Li Y, Zeng X, ... ... Letvin NL, et al. Adaptive immune response of Vgamma2Vdelta2+ T cells during mycobacterial infections. Science (New York, N.Y.). 295: 2255-8. PMID 11910108 DOI: 10.1126/Science.1068819  1
2002 Margolin DH, Saunders EF, Bronfin B, de Rosa N, Axthelm MK, Alvarez X, Letvin NL. High frequency of virus-specific B lymphocytes in germinal centers of simian-human immunodeficiency virus-infected rhesus monkeys. Journal of Virology. 76: 3965-73. PMID 11907236 DOI: 10.1128/JVI.76.8.3965-3973.2002  1
2002 Letvin NL, Barouch DH, Montefiori DC. Prospects for vaccine protection against HIV-1 infection and AIDS Annual Review of Immunology. 20: 73-99. PMID 11861598 DOI: 10.1146/annurev.immunol.20.081501.094854  1
2002 Santra S, Schmitz JE, Kuroda MJ, Lifton MA, Nickerson CE, Lord CI, Pal R, Franchini G, Letvin NL. Recombinant canarypox vaccine-elicited CTL specific for dominant and subdominant simian immunodeficiency virus epitopes in rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 168: 1847-53. PMID 11823518 DOI: 10.4049/jimmunol.168.4.1847  1
2002 Barouch DH, Kunstman J, Kuroda MJ, Schmitz JE, Santra S, Peyerl FW, Krivulka GR, Beaudry K, Lifton MA, Gorgone DA, Montefiori DC, Lewis MG, Wolinsky SM, Letvin NL. Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes. Nature. 415: 335-9. PMID 11797012 DOI: 10.1038/415335a  1
2002 Shiver JW, Fu TM, Chen L, Casimiro DR, Davies ME, Evans RK, Zhang ZQ, Simon AJ, Trigona WL, Dubey SA, Huang L, Harris VA, Long RS, Liang X, Handt L, ... ... Letvin NL, et al. Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity. Nature. 415: 331-5. PMID 11797011 DOI: 10.1038/415331a  1
2002 Barouch DH, Santra S, Tenner-Racz K, Racz P, Kuroda MJ, Schmitz JE, Jackson SS, Lifton MA, Freed DC, Perry HC, Davies ME, Shiver JW, Letvin NL. Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CSF. Journal of Immunology (Baltimore, Md. : 1950). 168: 562-8. PMID 11777947 DOI: 10.4049/jimmunol.168.2.562  1
2002 Koralnik IJ, Du Pasquier RA, Kuroda MJ, Schmitz JE, Dang X, Zheng Y, Lifton M, Letvin NL. Association of prolonged survival in HLA-A2+ progressive multifocal leukoencephalopathy patients with a CTL response specific for a commonly recognized JC virus epitope. Journal of Immunology (Baltimore, Md. : 1950). 168: 499-504. PMID 11751998 DOI: 10.4049/jimmunol.168.1.499  1
2002 McKay PF, Schmitz JE, Barouch DH, Kuroda MJ, Lifton MA, Nickerson CE, Gorgone DA, Letvin NL. Vaccine protection against functional CTL abnormalities in simian human immunodeficiency virus-infected rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 168: 332-7. PMID 11751978 DOI: 10.4049/jimmunol.168.1.332  1
2002 Pal R, Venzon D, Letvin NL, Santra S, Montefiori DC, Miller NR, Tryniszewska E, Lewis MG, VanCott TC, Hirsch V, Woodward R, Gibson A, Grace M, Dobratz E, Markham PD, et al. ALVAC-SIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiency Journal of Virology. 76: 292-302. PMID 11739694 DOI: 10.1128/Jvi.76.1.292-302.2002  1
2001 LaBonte ML, Hershberger KL, Korber B, Letvin NL. The KIR and CD94/NKG2 families of molecules in the rhesus monkey. Immunological Reviews. 183: 25-40. PMID 11782245 DOI: 10.1034/J.1600-065X.2001.1830103.X  1
2001 Schmitz JE, Veazey RS, Kuroda MJ, Levy DB, Seth A, Mansfield KG, Nickerson CE, Lifton MA, Alvarez X, Lackner AA, Letvin NL. Simian immunodeficiency virus (SIV)-specific cytotoxic T lymphocytes in gastrointestinal tissues of chronically SIV-infected rhesus monkeys. Blood. 98: 3757-61. PMID 11739183 DOI: 10.1182/blood.V98.13.3757  1
2001 Hel Z, Nacsa J, Kelsall B, Tsai WP, Letvin N, Parks RW, Tryniszewska E, Picker L, Lewis MG, Edghill-Smith Y, Moniuszko M, Pal R, Stevceva L, Altman JD, Allen TM, et al. Impairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques. Journal of Virology. 75: 11483-95. PMID 11689630 DOI: 10.1128/Jvi.75.23.11483-11495.2001  1
2001 Staats HF, Bradney CP, Gwinn WM, Jackson SS, Sempowski GD, Liao HX, Letvin NL, Haynes BF. Cytokine requirements for induction of systemic and mucosal CTL after nasal immunization. Journal of Immunology (Baltimore, Md. : 1950). 167: 5386-94. PMID 11673557 DOI: 10.4049/jimmunol.167.9.5386  1
2001 Charini WA, Kuroda MJ, Schmitz JE, Beaudry KR, Lin W, Lifton MA, Krivulka GR, Necker A, Letvin NL. Clonally diverse CTL response to a dominant viral epitope recognizes potential epitope variants Journal of Immunology. 167: 4996-5003. PMID 11673507 DOI: 10.4049/jimmunol.167.9.4996  1
2001 Barouch DH, Fu TM, Montefiori DC, Lewis MG, Shiver JW, Letvin NL. Vaccine-elicited immune responses prevent clinical AIDS in SHIV(89.6P)-infected rhesus monkeys. Immunology Letters. 79: 57-61. PMID 11595290 DOI: 10.1016/S0165-2478(01)00266-8  1
2001 Du Pasquier RA, Clark KW, Smith PS, Joseph JT, Mazullo JM, De Girolami U, Letvin NL, Koralnik IJ. JCV-specific cellular immune response correlates with a favorable clinical outcome in HIV-infected individuals with progressive multifocal leukoencephalopathy. Journal of Neurovirology. 7: 318-22. PMID 11517410 DOI: 10.1080/13550280152537175  1
2001 Barouch DH, Letvin NL. CD8+ cytotoxic T lymphocyte responses to lentiviruses and herpesviruses Current Opinion in Immunology. 13: 479-482. PMID 11498305 DOI: 10.1016/S0952-7915(00)00244-2  1
2001 Craiu A, Frost JD, Reimann KA, Strom TB, Letvin NL, Barouch DH, Xin Xiao Zheng, Kuroda MJ, Schmitz JE, Lifton MA, Steenbeke TD, Nickerson CE, Beaudry K. An IL-2/Ig fusion protein influences CD4+ T lymphocytes in naive and simian immunodeficiency virus-infected rhesus monkeys Aids Research and Human Retroviruses. 17: 873-886. PMID 11461674 DOI: 10.1089/088922201750290005  1
2001 Pfister LA, Letvin NL, Koralnik IJ. JC virus regulatory region tandem repeats in plasma and central nervous system isolates correlate with poor clinical outcome in patients with progressive multifocal leukoencephalopathy Journal of Virology. 75: 5672-5676. PMID 11356975 DOI: 10.1128/JVI.75.12.5672-5676.2001  1
2001 Etemad-Moghadam B, Rhone D, Steenbeke T, Sun Y, Manola J, Gelman R, Fanton JW, Racz P, Tenner-Racz K, Axthelm MK, Letvin NL, Sodroski J. Membrane-fusing capacity of the human immunodeficiency virus envelope proteins determines the efficiency of CD+ T-cell depletion in macaques infected by a simian-human immunodeficiency virus. Journal of Virology. 75: 5646-55. PMID 11356972 DOI: 10.1128/Jvi.75.12.5646-5655.2001  1
2001 Chen ZW, Li Y, Zeng X, Kuroda MJ, Schmitz JE, Shen Y, Lai X, Shen L, Letvin NL. The TCR repertoire of an immunodominant CD8+ T lymphocyte population Journal of Immunology. 166: 4525-4533. PMID 11254709 DOI: 10.4049/jimmunol.166.7.4525  1
2001 Hershberger KL, Shyam R, Miura A, Letvin NL. Diversity of the killer cell Ig-like receptors of rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 166: 4380-90. PMID 11254692 DOI: 10.4049/Jimmunol.166.7.4380  1
2001 Huete JMB, Chatis PA, Schmitz JE, Kuroda MJ, Letvin NL, Reimann KA. Detection of viral RNA in CD4-CD8- and CD4-CD8+ lymphocytes in vivo in rhesus monkeys infected with simian immunodeficiency virus of macaques Aids Research and Human Retroviruses. 17: 349-360. PMID 11242521 DOI: 10.1089/08892220150503717  1
2001 Koralnik IJ, Du Pasquier RA, Letvin NL. JC virus-specific cytotoxic T lymphocytes in individuals with progressive multifocal leukoencephalopathy Journal of Virology. 75: 3483-3487. PMID 11238876 DOI: 10.1128/JVI.75.7.3483-3487.2001  1
2001 Markus MB, Fincham JE. Helminthic infection and HIV vaccine trials. Science (New York, N.Y.). 291: 46-7. PMID 11192006 DOI: 10.1126/science.10.1126/SCIENCE.291.5501.46  1
2001 Seth A, Markee J, Hoering A, Sevin A, Sabath DE, Schmitz JE, Kuroda MJ, Lifton MA, Hirsch MS, Collier AC, Letvin NL, McElrath MJ. Alterations in T cell phenotype and human immunodeficiency virus type 1-specific cytotoxicity after potent antiretroviral therapy. The Journal of Infectious Diseases. 183: 722-9. PMID 11181148 DOI: 10.1086/318816  1
2001 Letvin NL, Bloom BR, Hoffman SL. Prospects for vaccines to protect against AIDS, tuberculosis, and malaria. Jama. 285: 606-11. PMID 11176867 DOI: 10.1001/jama.285.5.606  1
2001 Barouch DH, Craiu A, Santra S, Egan MA, Schmitz JE, Kuroda MJ, Fu TM, Nam JH, Wyatt LS, Lifton MA, Krivulka GR, Nickerson CE, Lord CI, Moss B, Lewis MG, ... ... Letvin NL, et al. Elicitation of high-frequency cytotoxic T-lymphocyte responses against both dominant and subdominant simian-human immunodeficiency virus epitopes by DNA vaccination of rhesus monkeys. Journal of Virology. 75: 2462-7. PMID 11160750 DOI: 10.1128/Jvi.75.5.2462-2467.2001  1
2001 Letvin NL, Walker BD. HIV versus the immune system: Another apparent victory for the virus Journal of Clinical Investigation. 107: 273-275. PMID 11160150  1
2001 Brenner MB, Letvin NL. Immunity to infection Current Opinion in Immunology. 13: 393-394. DOI: 10.1016/S0952-7915(00)00232-6  1
2000 Barouch DH, Letvin NL. Cytokine-induced augmentation of DNA vaccine-elicited SIV-specific immunity in rhesus monkeys Developments in Biologicals. 104: 85-92. PMID 11713828  1
2000 Barouch DH, Letvin NL. DNA vaccination for HIV-1 and SIV Intervirology. 43: 282-287. PMID 11251383 DOI: 10.1159/000053995  1
2000 Santra S, Barouch DH, Jackson SS, Kuroda MJ, Schmitz JE, Lifton MA, Sharpe AH, Letvin NL. Functional equivalency of B7-1 and B7-2 for costimulating plasmid DNA vaccine-elicited CTL responses. Journal of Immunology (Baltimore, Md. : 1950). 165: 6791-5. PMID 11120800 DOI: 10.4049/Jimmunol.165.12.6791  1
2000 Chen ZW, Shen Y, Davis IC, Shen L, Letvin NL, Fultz PN. Down-regulation of macaque γδ + T cells in lymphoid compartments after rectal infection with SIVsmmPBj14 Journal of Medical Primatology. 29: 143-147. PMID 11085576 DOI: 10.1034/J.1600-0684.2000.290307.X  1
2000 Kempf W, Margolin DH, Dezube BJ, Kadin ME, Letvin NL, Koralnik IJ. Clinicopathological characterization of an HIV-2-infected individual with two clonally unrelated primary lymphomas. American Journal of Hematology. 65: 302-6. PMID 11074559 DOI: 10.1002/1096-8652(200012)65:4<302::AID-AJH9>3.0.CO;2-4  1
2000 Barouch DH, Santra S, Schmitz JE, Kuroda MJ, Fu TM, Wagner W, Bilska M, Craiu A, Zheng XX, Krivulka GR, Beaudry K, Lifton MA, Nickerson CE, Trigona WL, Punt K, ... ... Letvin NL, et al. Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination. Science (New York, N.Y.). 290: 486-92. PMID 11039923 DOI: 10.1126/Science.290.5491.486  1
2000 Santra S, Barouch DH, Sharpe AH, Letvin NL. B7 co-stimulatory requirements differ for induction of immune responses by DNA, protein and recombinant pox virus vaccination European Journal of Immunology. 30: 2650-2659. PMID 11009099 DOI: 10.1002/1521-4141(200009)30:9<2650::Aid-Immu2650>3.0.Co;2-K  1
2000 Kuroda MJ, Schmitz JE, Lekutis C, Nickerson CE, Lifton MA, Franchini G, Harouse JM, Cheng-Mayer C, Letvin NL. Human immunodeficiency virus type 1 envelope epitope-specific CD4+ T lymphocytes in simian/human immunodeficiency virus-infected and vaccinated rhesus monkeys detected using a peptide-major histocompatibility complex class II tetramer Journal of Virology. 74: 8751-8756. PMID 10954578 DOI: 10.1128/JVI.74.18.8751-8756.2000  1
2000 Mylonakis E, Paliou M, Greenbough TC, Flaningan TP, Letvin NL, Rich JD. Report of a false-positive HIV test result and the potential use of additional tests in establishing HIV serostatus Archives of Internal Medicine. 160: 2386-2388. PMID 10927739  1
2000 Helmuth EF, Letvin NL, Margolin DH. Germline repertoire of the immunoglobulin V(H)3 family in rhesus monkeys. Immunogenetics. 51: 519-27. PMID 10912503 DOI: 10.1007/s002510000170  1
2000 Egan MA, Charini WA, Kuroda MJ, Schmitz JE, Racz P, Tenner-Racz K, Manson K, Wyand M, Lifton MA, Nickerson CE, Fu T, Shiver JW, Letvin NL. Simian immunodeficiency virus (SIV) gag DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses and control viral replication after pathogenic SIV infection. Journal of Virology. 74: 7485-95. PMID 10906202 DOI: 10.1128/JVI.74.16.7485-7495.2000  1
2000 LaBonte ML, Levy DB, Letvin NL. Characterization of rhesus monkey CD94/NKG2 family members and identification of novel transmembrane-deleted forms of NKG2-A, B, C, and D Immunogenetics. 51: 496-499. PMID 10866118 DOI: 10.1007/s002510050650  1
2000 Schmitz JE, Kuroda MJ, Veazey RS, Seth A, Taylor WM, Nickerson CE, Lifton MA, Dailey PJ, Forman MA, Racz P, Tenner-Racz K, Letvin NL. Simian immunodeficiency virus (SIV)-specific CTL are present in large numbers in livers of SIV-infected rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 164: 6015-9. PMID 10820285 DOI: 10.4049/jimmunol.164.11.6015  1
2000 Barouch DH, Craiu A, Kuroda MJ, Schmitz JE, Zheng XX, Santra S, Frost JD, Krivulka GR, Lifton MA, Crabbs CL, Heidecker G, Perry HC, Davies ME, Xie H, Nickerson CE, ... ... Letvin NL, et al. Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys. Proceedings of the National Academy of Sciences of the United States of America. 97: 4192-7. PMID 10759543 DOI: 10.1073/Pnas.050417697  1
2000 Seth A, Yasutomi Y, Jacoby H, Callery JC, Kaminsky SM, Koff WC, Nixon DF, Letvin NL. Evaluation of a lipopeptide immunogen as a therapeutic in HIV type 1-seropositive individuals. Aids Research and Human Retroviruses. 16: 337-43. PMID 10716371 DOI: 10.1089/088922200309214  1
2000 Seth A, Ourmanov I, Schmitz JE, Kuroda MJ, Lifton MA, Nickerson CE, Wyatt L, Carroll M, Moss B, Venzon D, Letvin NL, Hirsch VM. Immunization with a modified vaccinia virus expressing simian immunodeficiency virus (SIV) Gag-Pol primes for an anamnestic Gag-specific cytotoxic T-lymphocyte response and is associated with reduction of viremia after SIV challenge Journal of Virology. 74: 2502-2509. PMID 10684264 DOI: 10.1128/Jvi.74.6.2502-2509.2000  1
1999 Letvin NL, Schmitz JE, Jordan HL, Seth A, Hirsch VM, Reimann KA, Kuroda MJ. Cytotoxic T lymphocytes specific for the simian immunodeficiency virus. Immunological Reviews. 170: 127-34. PMID 10566147 DOI: 10.1111/j.1600-065X.1999.tb01334.x  1
1999 Zhang Z, Schuler T, Zupancic M, Wietgrefe S, Staskus KA, Reimann KA, Reinhart TA, Rogan M, Cavert W, Miller CJ, Veazey RS, Notermans D, Little S, Danner SA, Richman DD, ... ... Letvin NL, et al. Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells. Science (New York, N.Y.). 286: 1353-7. PMID 10558989 DOI: 10.1126/Science.286.5443.1353  1
1999 Koralnik IJ, Schmitz JE, Lifton MA, Forman MA, Letvin NL. Detection of JC virus DNA in peripheral blood cell subpopulations of HIV-1-infected individuals Journal of Neurovirology. 5: 430-435. PMID 10463865  1
1999 Santra S, Fultz PN, Letvin NL. Virus-specific cytotoxic T lymphocytes in human immunodeficiency virus type 1-infected chimpanzees Journal of Virology. 73: 7065-7069. PMID 10400811 DOI: 10.1128/Jvi.73.8.7065-7069.1999  1
1999 Schmitz JE, Lifton MA, Reimann KA, Montefiori DC, Shen L, Racz P, Tenner-Racz K, Ollert MW, Forman MA, Gelman RS, Vogel CW, Letvin NL. Effect of complement consumption by cobra venom factor on the course of primary infection with simian immunodeficiency virus in rhesus monkeys. Aids Research and Human Retroviruses. 15: 195-202. PMID 10029251 DOI: 10.1089/088922299311619  1
1999 Schmitz JE, Kuroda MJ, Santra S, Sasseville VG, Simon MA, Lifton MA, Racz P, Tenner-Racz K, Dalesandro M, Scallon BJ, Ghrayeb J, Forman MA, Montefiori DC, Rieber EP, Letvin NL, et al. Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes. Science (New York, N.Y.). 283: 857-60. PMID 9933172 DOI: 10.1126/Science.283.5403.857  1
1999 Koralnik IJ, Boden D, Mai VX, Lord CI, Letvin NL. JC virus DNA load in patients with and without progressive multifocal leukoencephalopathy Neurology. 52: 253-260. PMID 9932940  1
1998 Prince AM, Andrus L, Letvin NL. AIDS vaccine trials in chimpanzees [3] Science. 282: 2195-2196. PMID 9890826  1
1998 Letvin NL, Yasutomi Y, Shen L, Reimann KA, Chen ZW, Schmitz JE, Kuroda MJ. The CD8+ T lymphocyte response during primary SIVmac infection Advances in Experimental Medicine and Biology. 452: 177-179. PMID 9889971 DOI: 10.1007/978-1-4615-5355-7_19  1
1998 Letvin NL. What immunity can protect against HIV infection?: Editorial Journal of Clinical Investigation. 102: 1643-1644. PMID 9802877 DOI: 10.1172/JCI5440  1
1998 Karlsson GB, Halloran M, Schenten D, Lee J, Racz P, Tenner-Racz K, Manola J, Gelman R, Etemad-Moghadam B, Desjardins E, Wyatt R, Gerard NP, Marcon L, Margolin D, Fanton J, ... ... Letvin NL, et al. The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques. The Journal of Experimental Medicine. 188: 1159-71. PMID 9743534 DOI: 10.1084/Jem.188.6.1159  1
1998 Seth A, Ourmanov I, Kuroda MJ, Schmitz JE, Carroll MW, Wyatt LS, Moss B, Forman MA, Hirsch VM, Letvin NL. Recombinant modified vaccinia virus Ankara-simian immunodeficiency virus gag pol elicits cytotoxic T lymphocytes in rhesus monkeys detected by a major histocompatibility complex class I/peptide tetramer Proceedings of the National Academy of Sciences of the United States of America. 95: 10112-10116. PMID 9707609 DOI: 10.1073/Pnas.95.17.10112  1
1998 Letvin NL. Progress in the development of an HIV-1 vaccine Science. 280: 1875-1880. PMID 9632379 DOI: 10.1126/science.280.5371.1875  1
1998 Lekutis C, Letvin NL. Substitutions in a major histocompatibility complex class II-restricted human immunodeficiency virus type 1 gp120 epitope can affect CD4+ T-helper- cell function Journal of Virology. 72: 5840-5844. PMID 9621044  1
1998 Kuroda MJ, Schmitz JE, Barouch DH, Craiu A, Allen TM, Sette A, Watkins DI, Forman MA, Letvin NL. Analysis of gag-specific cytotoxic T lymphocytes in simian immunodeficiency virus-infected rhesus monkeys by cell staining with a tetrameric major histocompatibility complex class I-peptide complex Journal of Experimental Medicine. 187: 1373-1381. PMID 9565630 DOI: 10.1084/Jem.187.9.1373  1
1998 Cheynier R, Gratton S, Halloran M, Stahmer I, Letvin NL, Wain-Hobson S. Antigenic stimulation by BCG vaccine as an in vivo driving force for SIV replication and dissemination Nature Medicine. 4: 421-427. PMID 9546787 DOI: 10.1038/nm0498-421  1
1998 Montefiori DC, Reimann KA, Wyand MS, Manson K, Lewis MG, Collman RG, Sodroski JG, Bolognesi DP, Letvin NL. Neutralizing antibodies in sera from macaques infected with chimeric simian-human immunodeficiency virus containing the envelope glycoproteins of either a laboratory-adapted variant or a primary isolate of human immunodeficiency virus type 1 Journal of Virology. 72: 3427-3431. PMID 9525675 DOI: 10.1128/Jvi.72.4.3427-3431.1998  1
1997 Lekutis C, Letvin NL. HIV-1 Envelope-Specific CD4+ T Helper Cells from Simian/Human Immunodeficiency Virus-Infected Rhesus Monkeys Recognize Epitopes Restricted by MHC Class II DRB1*0406 and DRB*W201 Molecules Journal of Immunology. 159: 2049-2057. PMID 9257873  1
1997 Letvin NL, Montefiori DC, Yasutomi Y, Perry HC, Davies ME, Lekutis C, Alroy M, Freed DC, Lord CI, Handt LK, Liu MA, Shiver JW. Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination. Proceedings of the National Academy of Sciences of the United States of America. 94: 9378-83. PMID 9256490 DOI: 10.1073/pnas.94.17.9378  1
1997 Shiver JW, Davies ME, Yasutomi Y, Perry HC, Freed DC, Letvin NL, Liu MA. Anti-HIV env immunities elicited by nucleic acid vaccines. Vaccine. 15: 884-7. PMID 9234539 DOI: 10.1016/S0264-410X(96)00251-4  1
1997 Seth A, Zhang C, Letvin NL, Schlossman SF. Detection of apoptotic cells from peripheral blood of HIV-infected individuals using a novel monoclonal antibody. Aids (London, England). 11: 1059-61. PMID 9223744  1
1997 Reimann KA, Lin W, Bixler S, Browning B, Ehrenfels BN, Lucci J, Miatkowski K, Olson D, Parish TH, Rosa MD, Oleson FB, Hsu YM, Padlan EA, Letvin NL, Burkly LC. A humanized form of a CD4-specific monoclonal antibody exhibits decreased antigenicity and prolonged plasma half-life in rhesus monkeys while retaining its unique biological and antiviral properties. Aids Research and Human Retroviruses. 13: 933-43. PMID 9223409 DOI: 10.1089/aid.1997.13.933  1
1997 Lekutis C, Shiver JW, Liu MA, Letvin NL. HIV-1 env DNA vaccine administered to rhesus monkeys elicits MHC class II-restricted CD4+ T helper cells that secrete IFN-gamma and TNF-alpha. Journal of Immunology (Baltimore, Md. : 1950). 158: 4471-7. PMID 9127013  1
1996 Bachelder RE, Letvin NL. Postbinding functions of CD4 in HIV infection Trends in Microbiology. 4: 359-363. PMID 8885171 DOI: 10.1016/0966-842X(96)10043-3  1
1996 Kanai T, Thomas EK, Yasutomi Y, Letvin NL. IL-15 stimulates the expansion of AIDS virus-specific CTL. Journal of Immunology (Baltimore, Md. : 1950). 157: 3681-7. PMID 8871670  1
1996 Haigwood NL, Watson A, Sutton WF, McClure J, Lewis A, Ranchalis J, Travis B, Voss G, Letvin NL, Hu SL, Hirsch VM, Johnson PR. Passive immune globulin therapy in the SIV/macaque model: early intervention can alter disease profile. Immunology Letters. 51: 107-14. PMID 8811353 DOI: 10.1016/0165-2478(96)02563-1  1
1996 Voss G, Letvin NL. Definition of human immunodeficiency virus type 1 gp120 and gp41 cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I alleles in simian-human immunodeficiency virus-infected rhesus monkeys Journal of Virology. 70: 7335-7340. PMID 8794394  1
1996 Liu MA, Yasutomi Y, Davies ME, Perry HC, Freed DC, Letvin NL, Shiver JW. Vaccination of mice and nonhuman primates using HIV-gene-containing DNA Antibiotics and Chemotherapy. 48: 100-104. PMID 8726511 DOI: 10.1159/000425163  1
1996 Reimann KA, John TLI, Voss G, Lekutis C, Tenner-Racz K, Racz P, Lin W, Montefiori DC, Lee-Parritz DE, Yichen LU, Collman RG, Sodroski J, Letvin NL. An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys Journal of Virology. 70: 3198-3206. PMID 8627800 DOI: 10.1128/Jvi.70.5.3198-3206.1996  1
1996 Chen ZW, Shen L, Regan JD, Kou Z, Ghim SH, Letvin NL. The T cell receptor gene usage by simian immunodeficiency virus Gag-specific cytotoxic T lymphocytes in rhesus monkeys Journal of Immunology. 156: 1469-1475. PMID 8568249  1
1995 Genain CP, Nguyen MH, Letvin NL, Pearl R, Davis RL, Adelman M, Lees MB, Linington C, Hauser SL. Antibody facilitation of multiple sclerosis-like lesions in a nonhuman primate. The Journal of Clinical Investigation. 96: 2966-74. PMID 8675668 DOI: 10.1172/Jci118368  1
1995 Lekutis C, Letvin NL. MHC expression of African green monkeys of Barbados is limited in heterogeneity Journal of Medical Primatology. 24: 81-86. PMID 8613977  1
1995 Letvin NL, Li J, Halloran M, Cranage MP, Rud EW, Sodroski J. Prior infection with a nonpathogenic chimeric simian-human immunodeficiency virus does not efficiently protect macaques against challenge with simian immunodeficiency virus Journal of Virology. 69: 4569-4571. PMID 7769725 DOI: 10.1128/Jvi.69.7.4569-4571.1995  1
1995 Voss G, Li J, Manson K, Wyand M, Sodroski J, Letvin NL. Human immunodeficiency virus type 1 envelope glycoprotein-specific cytotoxic T lymphocytes in simian-human immunodeficiency virus-infected rhesus monkeys Virology. 208: 770-775. PMID 7747449 DOI: 10.1006/Viro.1995.1209  1
1995 Pelletier E, Saurin W, Cheynier R, Letvin NL, Wain-Hobson S. The tempo and mode of SIV quasispecies development in vivo calls for massive viral replication and clearance Virology. 208: 644-652. PMID 7747436 DOI: 10.1006/viro.1995.1195  1
1995 Massacesi L, Genain CP, Lee-Parritz D, Letvin NL, Canfield D, Hauser SL. Active and passively induced experimental autoimmune encephalomyelitis in common marmosets: a new model for multiple sclerosis. Annals of Neurology. 37: 519-30. PMID 7717689 DOI: 10.1002/Ana.410370415  1
1995 Bachelder RE, Bilancieri J, Lin W, Letvin NL. A human recombinant fab identifies a human immunodeficiency virus type 1-induced conformational change in cell surface-expressed CD4 Journal of Virology. 69: 5734-5742. PMID 7637018  1
1995 Lekutis C, Letvin NL. Biochemical and molecular characterization of rhesus monkey major histocompatibility complex class II DR Human Immunology. 43: 72-80. PMID 7558932 DOI: 10.1016/0198-8859(94)00155-J  1
1995 Yasutomi Y, McAdam SN, Boyson JE, Piekarczyk MS, Watkins DI, Letvin NL. A MHC class I B locus allele-restricted simian immunodeficiency virus envelope CTL epitope in rhesus monkeys Journal of Immunology. 154: 2516-2522. PMID 7532670  1
1995 Montefiori DC, Reimann KA, Letvin NL, Zhou J, Hu SL. Studies of complement-activating antibodies in the SIV/macaque model of acute primary infection and vaccine protection Aids Research and Human Retroviruses. 11: 963-970. PMID 7492443  1
1994 Shen L, Chen ZW, Letvin NL. The repertoire of cytotoxic T lymphocytes in the recognition of mutant simian immunodeficiency virus variants Journal of Immunology. 153: 5849-5854. PMID 7989780  1
1994 Morimoto C, Lord CI, Zhang C, Duke-Cohan JS, Letvin NL, Schlossman SF. Role of CD26/dipeptidyl peptidase IV in human immunodeficiency virus type 1 infection and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 91: 9960-4. PMID 7937926 DOI: 10.1073/pnas.91.21.9960  1
1994 Letvin NL, Reimann KA, Yasutomi Y, Ringler DJ, Yamamoto H. The SIV(mac) specific cytotoxic T lymphocyte response in the acutely infected rhesus monkey Current Topics in Microbiology and Immunology. 188: 175-184. PMID 7924426  1
1994 Chen ZW, Kou ZC, Shen L, Regan JD, Lord CI, Halloran M, Lee-Parritz D, Fultz PN, Letvin NL. An acutely lethal simian immunodeficiency virus stimulates expansion of Vβ7- And Vβ14-expressing T lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 91: 7501-7505. PMID 7914369 DOI: 10.1073/pnas.91.16.7501  1
1994 Watanabe N, McAdam SN, Boyson JE, Piekarczyk MS, Yasutomi Y, Watkins DI, Letvin NL. A simian immunodeficiency virus envelope V3 cytotoxic T-lymphocyte epitope in rhesus monkeys and its restricting major histocompatibility complex class I molecule mamu-A*02 Journal of Virology. 68: 6690-6696. PMID 7521921 DOI: 10.1128/Jvi.68.10.6690-6696.1994  1
1994 Genain CP, Lee-Parritz D, Nguyen MH, Massacesi L, Joshi N, Ferrante R, Hoffman K, Moseley M, Letvin NL, Hauser SL. In healthy primates, circulating autoreactive T cells mediate autoimmune disease. The Journal of Clinical Investigation. 94: 1339-45. PMID 7521889 DOI: 10.1172/Jci117454  1
1993 Chen ZW, Hughes AL, Ghim SH, Letvin NL, Watkins DI. Two more chimpanzee Patr-A locus alleles related to the HLA-A1/A2/A11 family Immunogenetics. 38: 238-240. PMID 8505066 DOI: 10.1007/Bf00211524  1
1993 Garber TL, Hughes AL, Letvin NL, Templeton JW, Watkins DI. Sequence and evolution of cattle MHC class I cDNAs: concerted evolution has not taken place in cattle Immunogenetics. 38: 11-20. PMID 8462989 DOI: 10.1007/Bf00216385  1
1993 Yasutomi Y, Reimann KA, Lord CI, Miller MD, Letvin NL. Simian immunodeficiency virus-specific CD8+ lymphocyte response in acutely infected rhesus monkeys Journal of Virology. 67: 1707-1711. PMID 8437240  1
1993 Letvin NL. Seminars in medicine of the Beth Israel Hospital, Boston: Vaccines against human immunodeficiency virus - Progress and prospects New England Journal of Medicine. 329: 1400-1405. PMID 8413438 DOI: 10.1056/NEJM199311043291908  1
1993 Letvin NL, Miller MD, Shen L, Chen ZW, Yasutomi Y. Simian immunodeficiency virus-specific cytotoxic T lymphocytes in rhesus monkeys: Characterization and vaccine induction Seminars in Immunology. 5: 215-223. PMID 8394161  1
1993 Chen ZW, Kou ZC, Shen L, Reimann KA, Letvin NL. Conserved T-cell receptor repertoire in simian immunodeficiency virus-infected rhesus monkeys Journal of Immunology. 151: 2177-2187. PMID 8393899  1
1993 Shen L, Mazzara GP, DiSciullo SO, Panicali DL, Letvin NL. Immunization with lentivirus-like particles elicits a potent SIV-specific recall cytotoxic T-lymphocyte response in rhesus monkeys Aids Research and Human Retroviruses. 9: 129-132. PMID 8384466 DOI: 10.1089/aid.1993.9.129  1
1993 Yasutomi Y, Palker TJ, Gardner MB, Haynes BF, Letvin NL. Synthetic peptide in mineral oil adjuvant elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes in rhesus monkeys Journal of Immunology. 151: 5096-5105. PMID 7691965  1
1993 Lairmore MD, Hofheinz DE, Letvin NL, Stoner CS, Pearlman S, Toedter GP. Detection of simian immunodeficiency virus and human immunodeficiency virus type 2 capsid antigens by a monoclonal antibody-based antigen capture assay. Aids Research and Human Retroviruses. 9: 565-71. PMID 7688521 DOI: 10.1089/Aid.1993.9.565  1
1992 Yamamoto H, Ringler DJ, Miller MD, Yasutomi Y, Hasunuma T, Letvin NL. Simian immunodeficiency virus-specific cytotoxic T lymphocytes are present in the aids-associated skin rash in rhesus monkeys Journal of Immunology. 149: 728-734. PMID 1624810  1
1992 Li J, Lord CI, Haseltine W, Letvin NL, Sodroski J. Infection of cynomolgus monkeys with a chimeric hiv-l/siv<inf>mac</inf> virus that expresses the HIV-1 envelope glycoproteins Journal of Acquired Immune Deficiency Syndromes. 5: 639-646. PMID 1613662  1
1992 Watanabe M, Boyson JE, Lord CI, Letvin NL. Chimpanzees immunized with recombinant soluble CD4 develop anti-self CD4 antibody responses with anti-human immunodeficiency virus activity Proceedings of the National Academy of Sciences of the United States of America. 89: 5103-5107. PMID 1594618  1
1992 Watkins DI, McAdam SN, Liu X, Strang CR, Milford EL, Levine CG, Garber TL, Dogon AL, Lord CI, Ghim SH, Troup GM, Hughes AL, Letvin NL. New recombinant HLA-B alleles in a tribe of South American Amerindians indicate rapid evolution of MHC class I loci Nature. 357: 329-333. PMID 1589035 DOI: 10.1038/357329A0  1
1992 Chen ZW, McAdam SN, Hughes AL, Dogon AL, Letvin NL, Watkins DI. Molecular cloning of orangutan and gibbon MHC class I cDNA: The HLA-A and -B loci diverged over 30 million years ago Journal of Immunology. 148: 2547-2554. PMID 1560209  1
1992 Letvin NL. Nonhuman primate models for HIV vaccine development Immunodeficiency Reviews. 3: 247-260. PMID 1510838  1
1992 Letvin NL, Chen ZW, Yamamoto H, Watanabe M. Active immune therapy for the treatment of HIV infections Aids Research and Human Retroviruses. 8: 1499. PMID 1466989  1
1992 Panicali DL, Mazzara G, Sullivan JL, Hesselton R, Shen L, Letvin N, Daniel M, Desrosiers R, Stott EJ. Use of lentivirus-like particles alone and in combination with live vaccinia-virus-based vaccines Aids Research and Human Retroviruses. 8: 1449. PMID 1466979 DOI: 10.1089/Aid.1992.8.1449  1
1992 Miller MD, Gould-Fogerite S, Shen L, Woods RM, Koenig S, Mannino RJ, Letvin NL. Vaccination of rhesus monkeys with synthetic peptide in a fusogenic proteoliposome elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes. The Journal of Experimental Medicine. 176: 1739-44. PMID 1460429 DOI: 10.1084/jem.176.6.1739  1
1992 Massacesi L, Joshi N, Lee-Parritz D, Rombos A, Letvin NL, Hauser SL. Experimental allergic encephalomyelitis in cynomolgus monkeys. Quantitation of T cell responses in peripheral blood. The Journal of Clinical Investigation. 90: 399-404. PMID 1379611 DOI: 10.1172/Jci115874  1
1992 Letvin NL. Animal models for the study of human immunodeficiency virus infections Current Opinion in Immunology. 4: 481-485. PMID 1356349 DOI: 10.1016/S0952-7915(06)80043-9  1
1992 Chen ZW, Yamamoto H, Watkins DI, Levinson G, Letvin NL. Predominant use of a T-cell receptor Vβ gene family in simian immunodeficiency virus gag-specific cytotoxic T lymphocytes in a rhesus monkey Journal of Virology. 66: 3913-3917. PMID 1316491 DOI: 10.1128/Jvi.66.6.3913-3917.1992  1
1991 Watanabe M, Levine CG, Shen L, Fisher RA, Letvin NL. Immunization of simian immunodeficiency virus-infected rhesus monkeys with soluble human CD4 elicits an antiviral response Proceedings of the National Academy of Sciences of the United States of America. 88: 4616-4620. PMID 2052546  1
1991 Letvin NL, Lord CI, King NW, Wyand MS, Myrick KV, Haseltine WA. Risks of handling HIV [5] Nature. 349: 573. PMID 2000134 DOI: 10.1038/349573A0  1
1991 Watanabe M, Chen ZW, Tsubota H, Lord CI, Levine CG, Letvin NL. Soluble human CD4 elicits an antibody response in rhesus monkeys that inhibits simian immunodeficiency virus replication Proceedings of the National Academy of Sciences of the United States of America. 88: 120-124. PMID 1986356  1
1991 Watkins DI, Chen ZW, Garber TL, Hughes AL, Letvin NL. Segmental exchange between MHC class I genes in a higher primate: recombination in the gorilla between the ancestor of a human non-functional gene and an A locus gene Immunogenetics. 34: 185-191. PMID 1894312 DOI: 10.1007/Bf00205822  1
1991 Autran B, Letvin NL. HIV epitopes recognized by cytotoxic T-lymphocytes Aids. 5. PMID 1726954  1
1991 Miller MD, Yamamoto H, Hughes AL, Watkins DI, Letvin NL. Definition of an epitope and MHC class I molecule recognized by Gag-specific cytotoxic T lymphocytes in SIVmac-infected rhesus monkeys Journal of Immunology. 147: 320-329. PMID 1711081  1
1991 Shen L, Chen ZW, Miller MD, Stallard V, Mazzara GP, Panicali DL, Letvin NL. Recombinant virus vaccine-induced SIV-specific CD8+ cytotoxic T lymphocytes Science. 252: 440-443. PMID 1708168 DOI: 10.1126/science.1708168  1
1991 Watanabe M, Ringler DJ, Fultz PN, Mackey JJ, Boyson JE, Levine CG, Letvin NL. A Chimpanzee-Passaged Human Immunodeficiency Virus Isolate Is Cytopathic for Chimpanzee Cells but Does Not Induce Disease Journal of Virology. 65: 3344-3348. PMID 1674550  1
1991 Watkins DI, Letvin NL. Limited MHC class I polymorphism is not essential for bone marrow chimerism in New World primates Immunogenetics. 33: 194-197. PMID 1672664 DOI: 10.1007/Bf01719240  1
1991 Letvin NL. Immune responses in lentivirus-infected animals Current Opinion in Immunology. 3: 559-563. PMID 1661600 DOI: 10.1016/0952-7915(91)90021-R  1
1991 Letvin NL, King NW. Naturally occurring animal models of the acquired immune deficiency syndrome (AIDS) American Journal of Physiologic Imaging. 6: 1-15. PMID 1645558  1
1991 Letvin NL, Harris NL, Vonsattel JP. A 45-year-old man with HIV infection, an epidural mass, and a history of treated pulmonary tuberculosis and a seminoma New England Journal of Medicine. 324: 42-51.  1
1990 Watanabe M, Ringler DJ, Nakamura M, DeLong PA, Letvin NL. Simian immunodeficiency virus inhibits bone marrow hematopoietic progenitor cell growth Journal of Virology. 64: 656-663. PMID 2296079  1
1990 Tsubota H, Winkler G, Meade HM, Jakubowski A, Thomas DW, Letvin NL. CD4-Pseudomonas exotoxin conjugates delay but do not fully inhibit human immunodeficiency virus replication in lymphocytes in vitro Journal of Clinical Investigation. 86: 1684-1689. PMID 2243139  1
1990 Letvin NL, King NW. Immunologic and pathologic manifestations of the infection of rhesus monkeys with simian immunodeficiency virus of macaques Journal of Acquired Immune Deficiency Syndromes. 3: 1023-1040. PMID 2213505  1
1990 Miller MD, Lord CI, Stallard V, Mazzara GP, Letvin NL. The gag-specific cytotoxic T lymphocytes in rhesus monkeys infected wit the simian immunodeficiency virus of macaques Journal of Immunology. 144: 122-128. PMID 2153161  1
1990 Watkins DI, Chen ZW, Hughes AL, Evans MG, Tedder TF, Letvin NL. Evolution of the MHC class I genes of a New World primate from ancestral homologues of human non-classical genes. Nature. 346: 60-3. PMID 2114550 DOI: 10.1038/346060A0  1
1990 Watkins DI, Chen ZW, Hughes AL, Hodi FS, Letvin NL. Genetically distinct cell populations in naturally occurring bone marrow-chimeric primates express similar MHC class I gene products Journal of Immunology. 144: 3726-3735. PMID 2110210  1
1990 Watkins DI, Letvin NL, Hughes AL, Tedder TF. Molecular cloning of cDNA that encode MHC class I molecules from a new world primate (Saguinus oedipus): Natural selection acts at positions that may affect peptide presentation to T cells Journal of Immunology. 144: 1136-1143. PMID 2104912  1
1990 Letvin NL. Animal models for AIDS Trends in Immunology. 11: 322-326. DOI: 10.1016/0167-5699(90)90127-U  1
1989 Tsubota H, Lord CI, Watkins DI, Morimoto C, Letvin NL. A cytotoxic T lymphocyte inhibits acquired immunodeficiency syndrome virus replication in peripheral blood lymphocytes Journal of Experimental Medicine. 169: 1421-1434. PMID 2784486 DOI: 10.1084/Jem.169.4.1421  1
1989 Reed MH, Shapiro ME, Strom TB, Milford EL, Carpenter CB, Weinberg DS, Reimann KA, Letvin NL, Waldmann TA, Kirkman RL. Prolongation of primate renal allograft survival by anti-tac, an anti-human IL-2 receptor monoclonal antibody Transplantation. 47: 55-59. PMID 2643232 DOI: 10.1097/00007890-198901000-00013  1
1989 Watkins DI, Shadduck JA, Stone ME, Lewin HA, Letvin NL. Isoelectric focusing of bovine major histocompatibility complex class I molecules Journal of Immunogenetics. 16: 233-245. PMID 2614073 DOI: 10.1111/J.1744-313X.1989.Tb00466.X  1
1989 Reimann KA, Evans MG, Chalifoux LV, Turner S, DeBoer DJ, King NW, Letvin NL. Clinicopathologic characterization of canine juvenile cellulitis. Veterinary Pathology. 26: 499-504. PMID 2603330 DOI: 10.1177/030098588902600606  1
1989 Watkins DI, Shadduck JA, Stephen Hodi F, Stone ME, Letvin NL. Use of CDNA probes specific for the human MHC class IIβ loci for tissue-typing nonhuman primates at their class IIβ loci Transplantation. 48: 170-174. PMID 2568708 DOI: 10.1097/00007890-198907000-00046  1
1989 Desrosiers RC, Wyand MS, Kodama T, Ringler DJ, Arthur LO, Sehgal PK, Letvin NL, King NW, Daniel MD. Vaccine protection against simian immunodeficiency virus infection. Proceedings of the National Academy of Sciences of the United States of America. 86: 6353-7. PMID 2548210 DOI: 10.1073/Pnas.86.16.6353  1
1989 Watanabe M, Reimann KA, DeLong PA, Liu T, Fisher RA, Letvin NL. Effect of recombinant soluble CD4 in rhesus monkeys infected with simian immunodeficiency virus of macaques Nature. 337: 267-270. PMID 2536140  1
1989 Tsubota H, Ringler DJ, Kannagi M, King NW, Letvin NL. Letter to the editor. III Journal of Immunology. 143: 3413.  1
1988 Watkins DI, Kannagi M, Stone ME, Letvin NL. Major histocompatibility complex class I molecules of nonhuman primates European Journal of Immunology. 18: 1425-1432. PMID 3169121 DOI: 10.1002/Eji.1830180919  1
1988 Morimoto C, Matsuyama T, Rudd CE, Forsgren A, Letvin NL, Schlossman SF. Role of the 2H4 molecule in the activation of suppressor inducer function European Journal of Immunology. 18: 731-737. PMID 2967762  1
1988 Kannagi M, Chalifoux LV, Lord CI, Letvin NL. Suppression of simian immunodeficiency virus replication in vitro by CD8+ lymphocytes Journal of Immunology. 140: 2237-2242. PMID 2965185  1
1988 Watkins DI, Hodi FS, Letvin NL. A primate species with limited major histocompatibility complex class I polymorphism Proceedings of the National Academy of Sciences of the United States of America. 85: 7714-7718. PMID 2902637 DOI: 10.1073/Pnas.85.20.7714  1
1988 Reimann KA, Goldmacher VS, Lambert JM, Chalifoux LV, Cook SB, Schlossman SF, Letvin NL. In vivo administration of lymphocyte-specific monoclonal antibodies in nonhuman primates. IV. Cytotoxic effect of an anti-T11-gelonin immunotoxin. The Journal of Clinical Investigation. 82: 129-38. PMID 2899092 DOI: 10.1172/JCI113560  1
1988 Daniel MD, Letvin NL, Seghal PK, Schmidt DK, Silva DP, Solomon KR, Hodi FS, Ringler DJ, Hunt RD, King NW, Desrosiers RC. Prevalence of antibodies to 3 retroviruses in a captive colony of macaque monkeys International Journal of Cancer. 41: 601-608. PMID 2895751 DOI: 10.1002/Ijc.2910410421  1
1988 Morimoto C, Rudd CE, Letvin NL, Hagan M, Schlossman SF. 2H1--a novel antigen involved in T lymphocyte triggering. Journal of Immunology (Baltimore, Md. : 1950). 140: 2165-70. PMID 2895150  1
1988 Kiyotaki M, Solomon KR, Letvin NL. Herpesvirus ateles immortalizes in vitro a CD3+CD4+CD8+ marmoset lymphocyte with NK function Journal of Immunology. 140: 730-736. PMID 2828471  1
1987 Daniel MD, Desrosiers RC, Letvin NL, King NW, Schmidt DK, Sehgal P, Hunt RD. Simian models for AIDS Cancer Detection and Prevention. Supplement : Official Publication of the International Society For Preventive Oncology, Inc. 1: 501-507. PMID 3480063  1
1987 Chalifoux LV, Ringler DJ, King NW, Sehgal PK, Desrosiers RC, Daniel MD, Letvin NL. Lymphadenopathy in macaques experimentally infected with the simian immunodeficiency virus (SIV) American Journal of Pathology. 128: 104-110. PMID 3037910  1
1987 Desrosiers RC, Letvin NL. Animal models for acquired immunodeficiency syndrome Reviews of Infectious Diseases. 9: 438-446. PMID 3037674 DOI: 10.1093/Clinids/9.3.438  1
1987 Desrosiers RC, Daniel MD, Letvin NL, King NW, Hunt RD. Origins of HTLV-4 Nature. 327: 107. PMID 3033515 DOI: 10.1038/327107A0  1
1987 Kannagi M, Kiyotaki M, King NW, Lord CI, Letvin NL. Simian immunodeficiency virus induces expression of class II major histocompatibility complex structures on infected target cells in vitro Journal of Virology. 61: 1421-1426. PMID 3033270  1
1987 Ringler DJ, Hancock WW, King NW, Letvin NL, Daniel MD, Desrosiers RC, Murphy GF. Immunophenotypic characterization of the cutaneous exanthem of SIV-infected rhesus monkeys. Apposition of degenerative Langerhans cells and cytotoxic lymphocytes during the development of acquired immunodeficiency syndrome American Journal of Pathology. 126: 199-207. PMID 3030113  1
1987 Yetz JM, Letvin NL. Macaque monkey type D retrovirus replicates in vitro in a distinct subpopulation of B lymphocytes Journal of General Virology. 68: 573-576. PMID 3029291  1
1987 Morimoto C, Steinberg AD, Letvin NL, Hagan M, Takeuchi T, Daley J, Levine H, Schlossman SF. A defect of immunoregulatory T cell subsets in systemic lupus erythematosus patients demonstrated with anti-2H4 antibody. The Journal of Clinical Investigation. 79: 762-8. PMID 2950134 DOI: 10.1172/JCI112882  1
1987 Morimoto C, Hafler DA, Weiner HL, Letvin NL, Hagan M, Daley J, Schlossman SF. Selective loss of the suppressor-inducer T-cell subset in progressive multiple sclerosis. Analysis with anti-2H4 monoclonal antibody. The New England Journal of Medicine. 316: 67-72. PMID 2946956 DOI: 10.1056/Nejm198701083160202  1
1987 Daniel MD, Letvin NL, Sehgal PK, Hunsmann G, Schmidt DK, King NW, Desrosiers RC. Long-term persistent infection of macaque monkeys with the simian immunodeficiency virus Journal of General Virology. 68: 3183-3189. PMID 2826656 DOI: 10.1099/0022-1317-68-12-3183  1
1987 Morimoto C, Rudd CE, Letvin NL, Schlossman SF. A novel epitope of the LFA-1 antigen which can distinguish killer effector and suppressor cells in human CD8 cells Nature. 330: 479-482. PMID 2446140  1
1987 Dillner J, Rabin H, Letvin N, Henle W, Henle G, Klein G. Nuclear DNA-binding proteins determined by the Epstein-Barr virus-related simian lymphotropic herpesviruses H. gorilla, H. pan, H. pongo and H. papio. The Journal of General Virology. 68: 1587-96. PMID 2438377 DOI: 10.1099/0022-1317-68-6-1587  1
1987 Letvin NL, Daniel MD, King NW, Arthur LO, Kiyotaki M, Kannagi M, Desrosiers RC. An HIV-related virus from macaques Annales De L'Institut Pasteur Virology. 138: 79-82. DOI: 10.1016/S0769-2617(87)80078-3  1
1986 Kannagi M, Kiyotaki M, Desrosiers RC, Reimann KA, King NW, Waldron LM, Letvin NL. Humoral immune responses to T cell tropic retrovirus simian T lymphotropic virus type III in monkeys with experimentally induced acquired immune deficiency-like syndrome Journal of Clinical Investigation. 78: 1229-1236. PMID 3771794 DOI: 10.1172/Jci112706  1
1986 Letvin NL, Goldmacher VS, Ritz J, Yetz JM, Schlossman SF, Lambert JM. In vivo administration of lymphocyte-specific monoclonal antibodies in nonhuman primates. In vivo stability of disulfide-linked immunotoxin conjugates Journal of Clinical Investigation. 77: 977-984. PMID 3081579 DOI: 10.1172/JCI112399  1
1986 Kiyotaki M, Desrosiers RC, Letvin NL. Herpesvirus saimiri strain 11 immortalizes a restricted marmoset T8 lymphocyte subpopulation in vitro Journal of Experimental Medicine. 164: 926-931. PMID 3018122 DOI: 10.1084/Jem.164.3.926  1
1986 Desrosiers RC, Silva DP, Waldron LM, Letvin NL. Nononcogenic deletion mutants of herpesvirus saimiri are defective for in vitro immortalization Journal of Virology. 57: 701-705. PMID 3003401 DOI: 10.1128/Jvi.57.2.701-705.1986  1
1986 Morimoto C, Letvin NL, Rudd CE, Hagan M, Takeuchi T, Schlossman SF. The role of the 2H4 molecule in the generation of suppressor function in Con A-activated T cells. Journal of Immunology (Baltimore, Md. : 1950). 137: 3247-53. PMID 2945865  1
1986 Morimoto C, Letvin NL, Distaso JA, Brown HM, Schlossman SF. The cellular basis for the induction of antigen-specific T8 suppressor cells European Journal of Immunology. 16: 198-204. PMID 2420607  1
1985 Picus J, Holley K, Aldrich WR, Griffin JD, Letvin NL. A naturally occurring bone marrow-chimeric primate. II. Environment dictates restriction on cytolytic T lymphocyte-target cell interactions Journal of Experimental Medicine. 162: 2035-2052. PMID 3934319  1
1985 Kanki PJ, McLane MF, King NW, Letvin NL, Hunt RD, Sehgal P, Daniel MD, Desrosiers RC, Essex M. Serologic identification and characterization of a macaque T-lymphotropic retrovirus closely related to HTLV-III. Science (New York, N.Y.). 228: 1199-201. PMID 3873705 DOI: 10.1126/Science.3873705  1
1985 Letvin NL, Morimoto C, Aldrich WR, Schlossman SF. Definition of the T-lymphocyte inducer of suppression in primates using a monoclonal antibody Cellular Immunology. 94: 360-368. PMID 3161622 DOI: 10.1016/0008-8749(85)90260-6  1
1985 Daniel MD, Letvin NL, King NW, Kannagi M, Sehgal PK, Hunt RD, Kanki PJ, Essex M, Desrosiers RC. Isolation of T-cell tropic HTLV-III-like retrovirus from macaques. Science (New York, N.Y.). 228: 1201-4. PMID 3159089 DOI: 10.1126/Science.3159089  1
1985 Picus J, Aldrich WR, Letvin NL. A naturally occurring bone-marrow-chimeric primate. I. Integrity of its immune system Transplantation. 39: 297-303. PMID 3156438  1
1985 Morimoto C, Letvin NL, Distaso JA, Aldrich WR, Schlossman SF. The isolation and characterization of the human suppressor inducer T cell subset Journal of Immunology. 134: 1508-1515. PMID 3155770  1
1985 Letvin NL, Epstein MA, Yetz JM, Kannagi M, Sehgal PK, Hunt RD. Development of large granular lymphocytes in owl monkeys following EBV inoculation. The Journal of Infectious Diseases. 152: 1352-3. PMID 2999264 DOI: 10.1093/infdis/152.6.1352  1
1985 Kannagi M, Yetz JM, Letvin NL. in vitro growth characteristics of simian T-lymphotropic virus type III Proceedings of the National Academy of Sciences of the United States of America. 82: 7053-7057. PMID 2996002  1
1985 Letvin NL, Daniel MD, Sehgal PK, Desrosiers RC, Hunt RD, Waldron LM, MacKey JJ, Schmidt DK, Chalifoux LV, King NW. Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III. Science (New York, N.Y.). 230: 71-3. PMID 2412295 DOI: 10.1126/Science.2412295  1
1985 Letvin NL, Linch DC, Beardsley GP, McIntyre KW, Miller BA, Nathan DG. Influence of cell cycle phase-specific agents on simian fetal hemoglobin synthesis Journal of Clinical Investigation. 75: 1999-2005. PMID 2409112 DOI: 10.1172/JCI111918  1
1984 Letvin NL, O'Connell MJ, Blake BJ, King NW. Hematogenous hexamitiasis in a macaque monkey with an immunodeficiency syndrome Journal of Infectious Diseases. 149: 828. PMID 6726014  1
1984 Daniel MD, King NW, Letvin NL, Hunt RD, Sehgal PK, Desrosiers RC. A new type D retrovirus isolated from macaques with an immunodeficiency syndrome. Science (New York, N.Y.). 223: 602-5. PMID 6695172 DOI: 10.1126/Science.6695172  1
1984 Chalifoux LV, King NW, Letvin NL. Morphologic changes in lymph nodes of macaques with an immunodeficiency syndrome Laboratory Investigation. 51: 22-26. PMID 6610800  1
1984 Letvin NL, Aldrich WR, Thorley-Lawson DA, Schlossman SF, Nadler LM. Surface antigen changes during B-lymphocyte activation in primates Cellular Immunology. 84: 163-170. PMID 6607777 DOI: 10.1016/0008-8749(84)90087-X  1
1984 Letvin NL, Hunt RD. An acquired immune deficiency syndrome of macaque monkeys. Annals of the New York Academy of Sciences. 437: 121-30. PMID 6598300  1
1984 Chalifoux LV, Schlossman SF, Letvin NL. Delineation of lymphocyte subsets in lymph nodes of nonhuman primates Clinical Immunology and Immunopathology. 31: 96-101. PMID 6421525 DOI: 10.1016/0090-1229(84)90193-4  1
1984 Hauser SL, Weiner HL, Che M, Shapiro ME, Gilles F, Letvin NL. Prevention of experimental allergic encephalomyelitis (EAE) in the SJL/J mouse by whole body ultraviolet radiation Journal of Immunology. 132: 1276-1281. PMID 6363536  1
1984 Palley LS, Schlossman SF, Letvin NL. Common tree shrews and primates share leukocyte membrane antigens Journal of Medical Primatology. 13: 67-71. PMID 6334161  1
1984 Letvin NL, Hunt RD, Finberg R. Animal models of AIDS. Seminars in Oncology. 11: 18-28. PMID 6232704  1
1984 Letvin NL, Linch DC, Beardsley GP, McIntyre KW, Nathan DG. Augmentation of fetal-hemoglobin production in anemic monkeys by hydroxyurea New England Journal of Medicine. 310: 869-873. PMID 6199670  1
1984 Letvin NL, King NW. Clinical and pathologic features of an acquired immune deficiency syndrome (AIDS) in macaque monkeys Advances in Veterinary Science and Comparative Medicine. 28: 237-265. PMID 6098170  1
1984 Homma T, Kanki PJ, King NW, Hunt RD, O'Connell MJ, Letvin NL, Daniel MD, Desrosiers RC, Yang CS, Essex M. Lymphoma in macaques: association with virus of human T lymphotrophic family. Science (New York, N.Y.). 225: 716-8. PMID 6087453 DOI: 10.1126/Science.6087453  1
1984 Letvin NL, Daniel MD, King NW. Experimental transmission of macaque immunodeficiency syndrome and isolation of new type D retrovirus from affected macaques Federation Proceedings. 43.  1
1983 Letvin NL, Todd RF, Palley LS, Schlossman SF, Griffin JD. Conservation of myeloid surface antigens on primate granulocytes Blood. 61: 408-410. PMID 6821706 DOI: 10.1182/Blood.V61.2.408.Bloodjournal612408  1
1983 Letvin NL, King NW, Reinherz EL, Hunt RD, Lane H, Schlossman SF. T lymphocyte surface antigens in primates. European Journal of Immunology. 13: 345-7. PMID 6602053 DOI: 10.1002/eji.1830130414  1
1983 Hunt RD, Blake BJ, Chalifoux LV, Sehgal PK, King NW, Letvin NL. Transmission of naturally occurring lymphoma in macaque monkeys. Proceedings of the National Academy of Sciences of the United States of America. 80: 5085-9. PMID 6576377  1
1983 King NW, Hunt RD, Letvin NL. Histopathologic changes in macaques with an acquired immunodeficiency syndrome (AIDS). The American Journal of Pathology. 113: 382-8. PMID 6316791  1
1983 Letvin NL, Eaton KA, Aldrich WR, Sehgal PK, Blake BJ, Schlossman SF, King NW, Hunt RD. Acquired immunodeficiency syndrome in a colony of macaque monkeys. Proceedings of the National Academy of Sciences of the United States of America. 80: 2718-22. PMID 6221343 DOI: 10.1073/pnas.80.9.2718  1
1982 Letvin NL, Huber BT, Benacerraf B. B-lymphocyte responses to trinitrophenyl-ficoll. II. Decreased splenic adherent cell function in mice expressing the xid gene. Cellular Immunology. 70: 241-7. PMID 6982103 DOI: 10.1016/0008-8749(82)90325-2  1
1982 Letvin NL, Rock KL, Nepom JT, Gramm CF, Benacerraf B. Antibody responses to trinitrophenyl (TNP)-L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) in microcultures: anti-hapten and anti-carrier responses appear to be under separable control. Cellular Immunology. 71: 89-98. PMID 6814767 DOI: 10.1016/0008-8749(82)90498-1  1
1982 Letvin NL, Kauffman RS, Finberg R. An adherent cell lyses virus-infected targets: Characterization, activation, and fine specificity of the cytotoxic cell Journal of Immunology. 129: 2396-2401. PMID 6292289  1
1982 Letvin NL. The genetic restriction of T lymphocyte-B lymphocyte interactions - An overview Survey of Immunologic Research. 1: 244-247. PMID 6227070 DOI: 10.1007/BF02918464  1
1982 Letvin NL, Rock KL, Nepom JT. Antibody responses to trinitrophenyl (TNP)-L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) in microcultures: anti-hapten and anti-carrier responses appear to be under separable control Federation Proceedings. 41.  1
1981 Letvin NL, Benacerraf B, Germain RN. B-lymphocyte responses to trinitrophenyl-conjugated Ficoll: requirement for T lymphocytes and Ia-bearing adherent cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 5113-7. PMID 6975477 DOI: 10.1073/Pnas.78.8.5113  1
1981 Letvin NL, Benacerraf B, Germain RN. Plaque-forming cell responses to trinitrophenyl (TNP)-L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) in microcultures are not under conventional Ir gene control. Journal of Immunology (Baltimore, Md. : 1950). 127: 1534-8. PMID 6792278  1
1981 Letvin NL, Kauffman RS, Finberg R. T lymphocyte immunity to reovirus: Cellular requirements for generation and role in clearance of primary infections Journal of Immunology. 127: 2334-2339. PMID 6271871  1
1981 Picus J, Germain RN, Fox IJ, Greene MI, Benacerraf B, Letvin NL. Immunologic effects of whole-body ultraviolet (uv) irradiation. III Defective splenic adherent cell function in alloantigen-stimulated T-cell proliferation. Cellular Immunology. 63: 300-7. PMID 6168395 DOI: 10.1016/0008-8749(81)90009-5  1
1980 Letvin NL, Fox IJ, Greene MI, Benacerraf B, Germain RN. Immunologic effects of whole body ultraviolet (UV) irradiation. II. Defect in splenic adherent cell antigen presentation for stimulation of T cell proliferation. Journal of Immunology (Baltimore, Md. : 1950). 125: 1402-4. PMID 6967900  1
1980 Letvin NL, Greene MI, Benacerraf B, Germain RN. Immunologic effects of whole-body ultraviolet irradiation: selective defect in splenic adherent cell function in vitro. Proceedings of the National Academy of Sciences of the United States of America. 77: 2881-5. PMID 6967214 DOI: 10.1073/Pnas.77.5.2881  1
1980 Letvin NL, Nepom JT, Greene MI, Benacerraf B, Germain RN. Loss of Ia-bearing splenic adherent cells after whole body ultraviolet irradiation. Journal of Immunology (Baltimore, Md. : 1950). 125: 2550-4. PMID 6933201  1
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