Norman Letvin - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Immunology, Microbiology Biology

337 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tomalka JA, Pelletier AN, Fourati S, Latif MB, Sharma A, Furr K, Carlson K, Lifton M, Gonzalez A, Wilkinson P, Franchini G, Parks R, Letvin N, Yates N, Seaton K, et al. The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination. Nature Immunology. PMID 34556879 DOI: 10.1038/s41590-021-01026-9  0.38
2021 Eslamizar L, Petrovas C, Leggat DJ, Furr K, Lifton ML, Levine G, Ma S, Fletez-Brant C, Hoyland W, Prabhakaran M, Narpala S, Boswell K, Yamamoto T, Liao HX, Pickup D, ... ... Letvin NL, et al. Recombinant MVA-prime elicits neutralizing antibody responses by inducing antigen-specific B cells in the germinal center. Npj Vaccines. 6: 15. PMID 33495459 DOI: 10.1038/s41541-020-00277-1  0.379
2017 Saunders KO, Nicely NI, Wiehe K, Bonsignori M, Meyerhoff RR, Parks R, Walkowicz WE, Aussedat B, Wu NR, Cai F, Vohra Y, Park PK, Eaton A, Go EP, Sutherland LL, ... ... Letvin NL, et al. Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates. Cell Reports. 18: 2175-2188. PMID 28249163 DOI: 10.1016/J.Celrep.2017.02.003  0.515
2017 Saunders KO, Nicely NI, Aussedat B, Wiehe K, Parks R, Vohra Y, Walkowicz WE, Park PK, Eaton A, Sutherland LL, Scearce R, Wu N, Bonsignori M, Meyerhoff RR, Lloyd KE, ... ... Letvin N, et al. HIV Envelope vaccination elicits asparagine 332 glycan-dependent antibodies that resemble broadly neutralizing antibody precursors Cell Reports. DOI: 10.2210/Pdb5Iie/Pdb  0.376
2016 Luo K, Liao HX, Zhang R, Easterhoff D, Wiehe K, Gurley TC, Armand LC, Allen AA, Von Holle TA, Marshall DJ, Whitesides JF, Pritchett J, Foulger A, Hernandez G, Parks R, ... ... Letvin NL, et al. Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques. Jci Insight. 1: e88522. PMID 27942585 DOI: 10.1172/Jci.Insight.88522  0.303
2016 Krebs KC, Tian M, Asmal M, Ling B, Nelson K, Henry K, Gibson R, Li Y, Han W, Shattock RJ, Veazey RS, Letvin N, Arts EJ, Gao Y. Infection of rhesus macaques with a pool of simian immunodeficiency virus with the envelope genes from acute HIV-1 infections. Aids Research and Therapy. 13: 41. PMID 27906032 DOI: 10.1186/S12981-016-0125-8  0.364
2016 Asmal M, Lane S, Tian M, Nickel G, Venner C, Dirk B, Dikeakos J, Luedemann C, Mach L, Balachandran H, Buzby A, Rao S, Letvin N, Gao Y, Arts EJ. Pathogenic infection of Rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV-1 infections. Virology. 499: 298-312. PMID 27723488 DOI: 10.1016/J.Virol.2016.09.021  0.426
2015 Qin L, Jiang G, Han J, Letvin NL. Regulatory T Cells Modulate DNA Vaccine Immunogenicity at Early Time via Functional CD4(+) T Cells and Antigen Duration. Frontiers in Immunology. 6: 510. PMID 26483796 DOI: 10.3389/fimmu.2015.00510  0.463
2015 Santra S, Tomaras GD, Warrier R, Nicely NI, Liao HX, Pollara J, Liu P, Alam SM, Zhang R, Cocklin SL, Shen X, Duffy R, Xia SM, Schutte RJ, Pemble Iv CW, ... ... Letvin NL, et al. Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques. Plos Pathogens. 11: e1005042. PMID 26237403 DOI: 10.1371/Journal.Ppat.1005042  0.358
2015 Korioth-Schmitz B, Perley CC, Sixsmith JD, Click EM, Lee S, Letvin NL, Frothingham R. Rhesus immune responses to SIV Gag expressed by recombinant BCG vectors are independent from pre-existing mycobacterial immunity. Vaccine. 33: 5715-22. PMID 26192357 DOI: 10.1016/j.vaccine.2015.07.010  0.331
2015 Hulot SL, Korber B, Giorgi EE, Vandergrift N, Saunders KO, Balachandran H, Mach LV, Lifton MA, Pantaleo G, Tartaglia J, Phogat S, Jacobs B, Kibler K, Perdiguero B, Gomez CE, ... ... Letvin NL, et al. Comparison of Immunogenicity in Rhesus Macaques of Transmitted-Founder, HIV-1 Group M Consensus, and Trivalent Mosaic Envelope Vaccines Formulated as a DNA Prime, NYVAC, and Envelope Protein Boost. Journal of Virology. 89: 6462-80. PMID 25855741 DOI: 10.1128/Jvi.00383-15  0.452
2015 Asmal M, Luedemann C, Lavine CL, Mach LV, Balachandran H, Brinkley C, Denny TN, Lewis MG, Anderson H, Pal R, Sok D, Le K, Pauthner M, Hahn BH, Shaw GM, ... ... Letvin NL, et al. Corrigendum to: Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes [Virology 475 (2015) 37-45] Virology. 478: 155-158. DOI: 10.1016/J.Virol.2015.01.023  0.348
2014 Panas MW, Sixsmith JD, White K, Korioth-Schmitz B, Shields ST, Moy BT, Lee S, Schmitz JE, Jacobs WR, Porcelli SA, Haynes BF, Letvin NL, Gillard GO. Gene deletions in Mycobacterium bovis BCG stimulate increased CD8+ T cell responses. Infection and Immunity. 82: 5317-26. PMID 25287928 DOI: 10.1128/Iai.02100-14  0.767
2014 Panas MW, Jain P, Yang H, Mitra S, Biswas D, Wattam AR, Letvin NL, Jacobs WR. Noncanonical SMC protein in Mycobacterium smegmatis restricts maintenance of Mycobacterium fortuitum plasmids. Proceedings of the National Academy of Sciences of the United States of America. 111: 13264-71. PMID 25197070 DOI: 10.1073/Pnas.1414207111  0.702
2014 Sixsmith JD, Panas MW, Lee S, Gillard GO, White K, Lifton MA, Balachandran H, Mach L, Miller JP, Lavine C, DeMarco CT, Tomaras GD, Gee C, Porcelli SA, Larsen MH, ... ... Letvin NL, et al. Recombinant Mycobacterium bovis bacillus Calmette-Guérin vectors prime for strong cellular responses to simian immunodeficiency virus gag in rhesus macaques. Clinical and Vaccine Immunology : Cvi. 21: 1385-95. PMID 25080550 DOI: 10.1128/Cvi.00324-14  0.788
2014 Panas MW, Letvin NL. Role for Gr-1+ cells in the control of high-dose Mycobacterium bovis recombinant BCG. Clinical and Vaccine Immunology : Cvi. 21: 1120-7. PMID 24920602 DOI: 10.1128/Cvi.00363-14  0.759
2014 Giorgi EE, Balachandran H, Muldoon M, Letvin NL, Haynes BF, Korber BT, Santra S. Cross-reactive potential of human T-lymphocyte responses in HIV-1 infection. Vaccine. 32: 3995-4000. PMID 24837783 DOI: 10.1016/J.Vaccine.2014.04.040  0.333
2014 Osuna CE, Gonzalez AM, Chang HH, Hung AS, Ehlinger E, Anasti K, Alam SM, Letvin NL. TCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeys. Plos Pathogens. 10: e1004069. PMID 24743648 DOI: 10.1371/journal.ppat.1004069  0.415
2014 Roederer M, Keele BF, Schmidt SD, Mason RD, Welles HC, Fischer W, Labranche C, Foulds KE, Louder MK, Yang ZY, Todd JP, Buzby AP, Mach LV, Shen L, Seaton KE, ... ... Letvin NL, et al. Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV. Nature. 505: 502-8. PMID 24352234 DOI: 10.1038/Nature12893  0.37
2014 McGee K, Haim H, Korioth-Schmitz B, Espy N, Javanbakht H, Letvin N, Sodroski J. The selection of low envelope glycoprotein reactivity to soluble CD4 and cold during simian-human immunodeficiency virus infection of rhesus macaques. Journal of Virology. 88: 21-40. PMID 24131720 DOI: 10.1128/Jvi.01558-13  0.424
2014 Sircar P, Furr KL, Letvin NL. Erratum: Corrigendum: Systemic vaccination induces clonally diverse SIV-specific CD8+ T-cell populations in systemic and mucosal compartments Mucosal Immunology. 7: 1019-1019. DOI: 10.1038/mi.2014.39  0.339
2013 Chen CY, Yao S, Huang D, Wei H, Sicard H, Zeng G, Jomaa H, Larsen MH, Jacobs WR, Wang R, Letvin N, Shen Y, Qiu L, Shen L, Chen ZW. Phosphoantigen/IL2 expansion and differentiation of Vγ2Vδ2 T cells increase resistance to tuberculosis in nonhuman primates. Plos Pathogens. 9: e1003501. PMID 23966854 DOI: 10.1371/Journal.Ppat.1003501  0.407
2013 Fouda GG, Amos JD, Wilks AB, Pollara J, Ray CA, Chand A, Kunz EL, Liebl BE, Whitaker K, Carville A, Smith S, Colvin L, Pickup DJ, Staats HF, Overman G, ... ... Letvin NL, et al. Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk. Journal of Virology. 87: 6986-99. PMID 23596289 DOI: 10.1128/Jvi.00528-13  0.379
2013 Frencher JT, Ryan-Pasyeur BK, Huang D, Wang RC, McMullen PD, Letvin NL, Collins WE, Freitag NE, Malkovsky M, Chen CY, Shen L, Chen ZW. SHIV antigen immunization alters patterns of immune responses to SHIV/malaria coinfection and protects against life-threatening SHIV-related malaria. The Journal of Infectious Diseases. 208: 260-70. PMID 23568175 DOI: 10.1093/Infdis/Jit151  0.434
2013 Hellmann I, Letvin NL, Schmitz JE. KIR2DL4 copy number variation is associated with CD4+ T-cell depletion and function of cytokine-producing NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques. Journal of Virology. 87: 5305-10. PMID 23449795 DOI: 10.1128/JVI.02949-12  0.351
2013 Liao HX, Bonsignori M, Alam SM, McLellan JS, Tomaras GD, Moody MA, Kozink DM, Hwang KK, Chen X, Tsao CY, Liu P, Lu X, Parks RJ, Montefiori DC, Ferrari G, ... ... Letvin NL, et al. Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2. Immunity. 38: 176-86. PMID 23313589 DOI: 10.1016/J.Immuni.2012.11.011  0.327
2013 Bivas-Benita M, Gillard GO, Bar L, White KA, Webby RJ, Hovav AH, Letvin NL. Airway CD8(+) T cells induced by pulmonary DNA immunization mediate protective anti-viral immunity. Mucosal Immunology. 6: 156-66. PMID 22806099 DOI: 10.1038/mi.2012.59  0.436
2013 Sircar P, Furr KL, Letvin NL. Systemic vaccination induces clonally diverse SIV-specific CD8+ T-cell populations in systemic and mucosal compartments Mucosal Immunology. 6: 93-103. PMID 22763409 DOI: 10.1038/mi.2012.52  0.455
2012 Fischer W, Apetrei C, Santiago ML, Li Y, Gautam R, Pandrea I, Shaw GM, Hahn BH, Letvin NL, Nabel GJ, Korber BT. Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages. Journal of Virology. 86: 13217-31. PMID 23055550 DOI: 10.1128/Jvi.01862-12  0.335
2012 Grant EV, Thomas M, Fortune J, Klibanov AM, Letvin NL. Enhancement of plasmid DNA immunogenicity with linear polyethylenimine. European Journal of Immunology. 42: 2937-48. PMID 22886924 DOI: 10.1002/Eji.201242410  0.786
2012 Bolton DL, Santra S, Swett-Tapia C, Custers J, Song K, Balachandran H, Mach L, Naim H, Kozlowski PA, Lifton M, Goudsmit J, Letvin N, Roederer M, Radoševi? K. Priming T-cell responses with recombinant measles vaccine vector in a heterologous prime-boost setting in non-human primates. Vaccine. 30: 5991-8. PMID 22732429 DOI: 10.1016/J.Vaccine.2012.06.029  0.51
2012 Flatz L, Cheng C, Wang L, Foulds KE, Ko SY, Kong WP, Roychoudhuri R, Shi W, Bao S, Todd JP, Asmal M, Shen L, Donaldson M, Schmidt SD, Gall JG, ... ... Letvin NL, et al. Gene-based vaccination with a mismatched envelope protects against simian immunodeficiency virus infection in nonhuman primates. Journal of Virology. 86: 7760-70. PMID 22593152 DOI: 10.1128/Jvi.00599-12  0.434
2012 Yeh WW, Brassard LM, Miller CA, Basavapathruni A, Zhang J, Rao SS, Nabel GJ, Mascola JR, Letvin NL, Seaman MS. Envelope variable region 4 is the first target of neutralizing antibodies in early simian immunodeficiency virus mac251 infection of rhesus monkeys. Journal of Virology. 86: 7052-9. PMID 22532675 DOI: 10.1128/Jvi.00107-12  0.355
2012 Santra S, Muldoon M, Watson S, Buzby A, Balachandran H, Carlson KR, Mach L, Kong WP, McKee K, Yang ZY, Rao SS, Mascola JR, Nabel GJ, Korber BT, Letvin NL. Breadth of cellular and humoral immune responses elicited in rhesus monkeys by multi-valent mosaic and consensus immunogens. Virology. 428: 121-7. PMID 22521913 DOI: 10.1016/J.Virol.2012.03.012  0.4
2012 Yamamoto T, Johnson MJ, Price DA, Wolinsky DI, Almeida JR, Petrovas C, Nason M, Yeh WW, Shen L, Roederer M, Rao SS, McDermott AB, Lefebvre F, Nabel GJ, Haddad EK, ... Letvin NL, et al. Virus inhibition activity of effector memory CD8(+) T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection. Journal of Virology. 86: 5877-84. PMID 22419810 DOI: 10.1128/Jvi.00315-12  0.485
2012 Hulot S, Korber B, Pantaleo G, Tartaglia J, Jacobs B, Perdiguero B, Gomez C, Esteban M, Letvin N, Seaman M, Haynes B, Santra S. Comparison of the depth of vaccine-elicited HIV-1 Env epitope-specific CD8+ T lymphocyte responses Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P288  0.556
2012 Fouda G, Amos J, Wilks A, Chand A, Montefiori D, Haynes B, Letvin N, Pickup D, Liao H, Permar S. Vaccine-elicited systemic and mucosal humoral responses of lactating rhesus monkeys vaccinated with the transmitted/founder HIV Envelope 1086C Retrovirology. 9: O20. DOI: 10.1186/1742-4690-9-S2-O20  0.463
2011 Hellmann I, Lim SY, Gelman RS, Letvin NL. Association of activating KIR copy number variation of NK cells with containment of SIV replication in rhesus monkeys. Plos Pathogens. 7: e1002436. PMID 22194686 DOI: 10.1371/journal.ppat.1002436  0.311
2011 Jackson SS, Schmitz JE, Letvin NL. Anti-gamma interferon antibodies enhance the immunogenicity of recombinant adenovirus vectors. Clinical and Vaccine Immunology : Cvi. 18: 1969-78. PMID 21900534 DOI: 10.1128/CVI.05180-11  0.341
2011 Mahlokozera T, Kang HH, Goonetilleke N, Stacey AR, Lovingood RV, Denny TN, Kalilani L, Bunn JE, Meshnick SR, Borrow P, Letvin NL, Permar SR. The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk. Plos One. 6: e23735. PMID 21886819 DOI: 10.1371/Journal.Pone.0023735  0.34
2011 Cale EM, Bazick HS, Rianprakaisang TA, Alam SM, Letvin NL. Mutations in a dominant Nef epitope of simian immunodeficiency virus diminish TCR:epitope peptide affinity but not epitope peptide:MHC class I binding. Journal of Immunology (Baltimore, Md. : 1950). 187: 3300-13. PMID 21841125 DOI: 10.4049/Jimmunol.1101080  0.762
2011 Gillard GO, Bivas-Benita M, Hovav AH, Grandpre LE, Panas MW, Seaman MS, Haynes BF, Letvin NL. Thy1+ NK [corrected] cells from vaccinia virus-primed mice confer protection against vaccinia virus challenge in the absence of adaptive lymphocytes. Plos Pathogens. 7: e1002141. PMID 21829360 DOI: 10.1371/Journal.Ppat.1002141  0.769
2011 Yeh WW, Rao SS, Lim SY, Zhang J, Hraber PT, Brassard LM, Luedemann C, Todd JP, Dodson A, Shen L, Buzby AP, Whitney JB, Korber BT, Nabel GJ, Mascola JR, ... Letvin NL, et al. The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys. Journal of Virology. 85: 10389-98. PMID 21775457 DOI: 10.1128/Jvi.00854-11  0.304
2011 Sun Y, Asmal M, Lane S, Permar SR, Schmidt SD, Mascola JR, Letvin NL. Antibody-dependent cell-mediated cytotoxicity in simian immunodeficiency virus-infected rhesus monkeys. Journal of Virology. 85: 6906-12. PMID 21593181 DOI: 10.1128/Jvi.00326-11  0.362
2011 Letvin NL, Rao SS, Montefiori DC, Seaman MS, Sun Y, Lim SY, Yeh WW, Asmal M, Gelman RS, Shen L, Whitney JB, Seoighe C, Lacerda M, Keating S, Norris PJ, et al. Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. Science Translational Medicine. 3: 81ra36. PMID 21543722 DOI: 10.1126/Scitranslmed.3002351  0.439
2011 Hulot SL, Cale EM, Korber BT, Letvin NL. Vaccine-induced CD8+ T lymphocytes of rhesus monkeys recognize variant forms of an HIV epitope but do not mediate optimal functional activity. Journal of Immunology (Baltimore, Md. : 1950). 186: 5663-74. PMID 21490161 DOI: 10.4049/Jimmunol.1100287  0.791
2011 Asmal M, Sun Y, Lane S, Yeh W, Schmidt SD, Mascola JR, Letvin NL. Antibody-dependent cell-mediated viral inhibition emerges after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys coincident with gp140-binding antibodies and is effective against neutralization-resistant viruses. Journal of Virology. 85: 5465-75. PMID 21450829 DOI: 10.1128/Jvi.00313-11  0.348
2011 Geiben-Lynn R, Frimpong-Boateng K, Letvin NL. Modulation of plasmid DNA vaccine antigen clearance by caspase 12 RNA interference potentiates vaccination. Clinical and Vaccine Immunology : Cvi. 18: 533-8. PMID 21325489 DOI: 10.1128/CVI.00390-10  0.342
2011 Cale EM, Hraber P, Giorgi EE, Fischer W, Bhattacharya T, Leitner T, Yeh WW, Gleasner C, Green LD, Han CS, Korber B, Letvin NL. Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection. Journal of Virology. 85: 3746-57. PMID 21307185 DOI: 10.1128/Jvi.02420-10  0.794
2011 Yeh W, Rao S, Lim S, Zhang J, Hraber P, Brassard L, Luedemann C, Todd JP, Dodson A, Shen L, Buzby A, Whitney J, Korber B, Nabel G, Mascola J, ... Letvin N, et al. TRIM5 modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys F1000research. 2. DOI: 10.7490/F1000Research.1089571.1  0.375
2011 Gillard GO, Bivas-Benita M, Hovav A, Grandpre LE, Panas MW, Seaman MS, Haynes BF, Letvin NL. Correction: Thy1+Nk Cells from Vaccinia Virus-Primed Mice Confer Protection against Vaccinia Virus Challenge in the Absence of Adaptive Lymphocytes Plos Pathogens. 7. DOI: 10.1371/annotation/b29086ef-e08d-444c-8113-18a6dd429a7c  0.755
2010 Barker BR, Gladstone MN, Gillard GO, Panas MW, Letvin NL. Critical role for IL-21 in both primary and memory anti-viral CD8+ T-cell responses. European Journal of Immunology. 40: 3085-96. PMID 21061439 DOI: 10.1002/Eji.200939939  0.8
2010 Wilks AB, Christian EC, Seaman MS, Sircar P, Carville A, Gomez CE, Esteban M, Pantaleo G, Barouch DH, Letvin NL, Permar SR. Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 185: 7097-106. PMID 21041730 DOI: 10.4049/Jimmunol.1002751  0.633
2010 Manuel ER, Yeh WW, Balachandran H, Clarke RH, Lifton MA, Letvin NL. Vaccination reduces simian-human immunodeficiency virus sequence reversion through enhanced viral control. Journal of Virology. 84: 12782-9. PMID 20881040 DOI: 10.1128/Jvi.01193-10  0.756
2010 Liu J, Keele BF, Li H, Keating S, Norris PJ, Carville A, Mansfield KG, Tomaras GD, Haynes BF, Kolodkin-Gal D, Letvin NL, Hahn BH, Shaw GM, Barouch DH. Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. Journal of Virology. 84: 10406-12. PMID 20686016 DOI: 10.1128/Jvi.01155-10  0.552
2010 Sun Y, Santra S, Buzby AP, Mascola JR, Nabel GJ, Letvin NL. Recombinant vector-induced HIV/SIV-specific CD4+ T lymphocyte responses in rhesus monkeys. Virology. 406: 48-55. PMID 20667574 DOI: 10.1016/J.Virol.2010.07.004  0.49
2010 Sircar P, Furr KL, Dorosh LA, Letvin NL. Clonal repertoires of virus-specific CD8+ T lymphocytes are shared in mucosal and systemic compartments during chronic simian immunodeficiency virus infection in rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 185: 2191-9. PMID 20624939 DOI: 10.4049/jimmunol.1001340  0.392
2010 Lim SY, Chan T, Gelman RS, Whitney JB, O'Brien KL, Barouch DH, Goldstein DB, Haynes BF, Letvin NL. Contributions of Mamu-A*01 status and TRIM5 allele expression, but not CCL3L copy number variation, to the control of SIVmac251 replication in Indian-origin rhesus monkeys. Plos Genetics. 6: e1000997. PMID 20585621 DOI: 10.1371/Journal.Pgen.1000997  0.486
2010 Permar SR, Wilks AB, Ehlinger EP, Kang HH, Mahlokozera T, Coffey RT, Carville A, Letvin NL, Seaman MS. Limited contribution of mucosal IgA to Simian immunodeficiency virus (SIV)-specific neutralizing antibody response and virus envelope evolution in breast milk of SIV-infected, lactating rhesus monkeys. Journal of Virology. 84: 8209-18. PMID 20519381 DOI: 10.1128/Jvi.00656-10  0.33
2010 Bivas-Benita M, Bar L, Gillard GO, Kaufman DR, Simmons NL, Hovav AH, Letvin NL. Efficient generation of mucosal and systemic antigen-specific CD8+ T-cell responses following pulmonary DNA immunization. Journal of Virology. 84: 5764-74. PMID 20335249 DOI: 10.1128/JVI.02202-09  0.413
2010 Santra S, Liao HX, Zhang R, Muldoon M, Watson S, Fischer W, Theiler J, Szinger J, Balachandran H, Buzby A, Quinn D, Parks RJ, Tsao CY, Carville A, Mansfield KG, ... ... Letvin NL, et al. Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys. Nature Medicine. 16: 324-8. PMID 20173754 DOI: 10.1038/Nm.2108  0.495
2010 Zahn RC, Rett MD, Li M, Tang H, Korioth-Schmitz B, Balachandran H, White R, Pryputniewicz S, Letvin NL, Kaur A, Montefiori DC, Carville A, Hirsch VM, Allan JS, Schmitz JE. Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease. Blood. 115: 3070-8. PMID 20147699 DOI: 10.1182/Blood-2009-10-245225  0.39
2010 Permar SR, Kang HH, Carville A, Wilks AB, Mansfield KG, Rao SS, Letvin NL. Preservation of memory CD4(+) T lymphocytes in breast milk of lactating rhesus monkeys during acute simian immunodeficiency virus infection. The Journal of Infectious Diseases. 201: 302-10. PMID 20001855 DOI: 10.1086/649229  0.366
2010 Basavapathruni A, Yeh WW, Coffey RT, Whitney JB, Hraber PT, Giri A, Korber BT, Rao SS, Nabel GJ, Mascola JR, Seaman MS, Letvin NL. Envelope vaccination shapes viral envelope evolution following simian immunodeficiency virus infection in rhesus monkeys. Journal of Virology. 84: 953-63. PMID 19906933 DOI: 10.1128/Jvi.01679-09  0.384
2009 Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, Letvin NL. Non-classical natural killer T cells modulate plasmid DNA vaccine antigen expression and vaccine-elicited immune responses by MCP-1 secretion after interaction with a beta2-microglobulin-independent CD1d. The Journal of Biological Chemistry. 284: 33800-6. PMID 19833737 DOI: 10.1074/Jbc.M109.019638  0.692
2009 Hovav AH, Santosuosso M, Bivas-Benita M, Plair A, Cheng A, Elnekave M, Righi E, Chen T, Kashiwagi S, Panas MW, Xiang SH, Furmanov K, Letvin NL, Poznansky MC. X4 human immunodeficiency virus type 1 gp120 down-modulates expression and immunogenicity of codelivered antigens. Journal of Virology. 83: 10941-50. PMID 19692474 DOI: 10.1128/Jvi.00394-09  0.777
2009 Rodríguez A, Mintardjo R, Tax D, Gillissen G, Custers J, Pau MG, Klap J, Santra S, Balachandran H, Letvin NL, Goudsmit J, Radosevi? K. Evaluation of a prime-boost vaccine schedule with distinct adenovirus vectors against malaria in rhesus monkeys. Vaccine. 27: 6226-33. PMID 19686691 DOI: 10.1016/J.Vaccine.2009.07.106  0.368
2009 Santra S, Sun Y, Korioth-Schmitz B, Fitzgerald J, Charbonneau C, Santos G, Seaman MS, Ratcliffe SJ, Montefiori DC, Nabel GJ, Ertl HCJ, Letvin NL. Heterologous prime/boost immunizations of rhesus monkeys using chimpanzee adenovirus vectors Vaccine. 27: 5837-5845. PMID 19660588 DOI: 10.1016/J.Vaccine.2009.07.050  0.409
2009 Sun Y, Bailer RT, Rao SS, Mascola JR, Nabel GJ, Koup RA, Letvin NL. Systemic and mucosal T-lymphocyte activation induced by recombinant adenovirus vaccines in rhesus monkeys. Journal of Virology. 83: 10596-604. PMID 19656883 DOI: 10.1128/Jvi.01170-09  0.439
2009 Manuel ER, Yeh WW, Seaman MS, Furr K, Lifton MA, Hulot SL, Autissier P, Letvin NL. Dominant CD8+ T-lymphocyte responses suppress expansion of vaccine-elicited subdominant T lymphocytes in rhesus monkeys challenged with pathogenic simian-human immunodeficiency virus. Journal of Virology. 83: 10028-35. PMID 19641002 DOI: 10.1128/Jvi.01015-09  0.795
2009 Hulot SL, Seaman MS, Sen P, Autissier PA, Manuel ER, Letvin NL. Diverse cross-reactive potential and Vbeta gene usage of an epitope-specific cytotoxic T-lymphocyte population in monkeys immunized with diverse human immunodeficiency virus type 1 Env immunogens. Journal of Virology. 83: 9803-12. PMID 19640988 DOI: 10.1128/Jvi.00776-09  0.778
2009 Whitney JB, Luedemann C, Hraber P, Rao SS, Mascola JR, Nabel GJ, Letvin NL. T-cell vaccination reduces simian immunodeficiency virus levels in semen. Journal of Virology. 83: 10840-3. PMID 19640980 DOI: 10.1128/Jvi.01202-09  0.378
2009 Goonetilleke N, Liu MK, Salazar-Gonzalez JF, Ferrari G, Giorgi E, Ganusov VV, Keele BF, Learn GH, Turnbull EL, Salazar MG, Weinhold KJ, Moore S, Letvin N, Haynes BF, et al. The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. The Journal of Experimental Medicine. 206: 1253-72. PMID 19487423 DOI: 10.1084/Jem.20090365  0.516
2009 Korber BT, Letvin NL, Haynes BF. T-cell vaccine strategies for human immunodeficiency virus, the virus with a thousand faces. Journal of Virology. 83: 8300-14. PMID 19439471 DOI: 10.1128/Jvi.00114-09  0.463
2009 Chen CY, Huang D, Wang RC, Shen L, Zeng G, Yao S, Shen Y, Halliday L, Fortman J, McAllister M, Estep J, Hunt R, Vasconcelos D, Du G, Porcelli SA, ... ... Letvin NL, et al. A critical role for CD8 T cells in a nonhuman primate model of tuberculosis. Plos Pathogens. 5: e1000392. PMID 19381260 DOI: 10.1371/Journal.Ppat.1000392  0.394
2009 Cayabyab MJ, Korioth-Schmitz B, Sun Y, Carville A, Balachandran H, Miura A, Carlson KR, Buzby AP, Haynes BF, Jacobs WR, Letvin NL. Recombinant Mycobacterium bovis BCG prime-recombinant adenovirus boost vaccination in rhesus monkeys elicits robust polyfunctional simian immunodeficiency virus-specific T-cell responses. Journal of Virology. 83: 5505-13. PMID 19297477 DOI: 10.1128/Jvi.02544-08  0.46
2009 Grandpre LE, Duke-Cohan JS, Ewald BA, Devoy C, Barouch DH, Letvin NL, Reinherz EL, Baden LR, Dolin R, Seaman MS. Immunogenicity of recombinant Modified Vaccinia Ankara following a single or multi-dose vaccine regimen in rhesus monkeys. Vaccine. 27: 1549-56. PMID 19168105 DOI: 10.1016/j.vaccine.2009.01.010  0.579
2009 Yeh WW, Jaru-Ampornpan P, Nevidomskyte D, Asmal M, Rao SS, Buzby AP, Montefiori DC, Korber BT, Letvin NL. Partial protection of Simian immunodeficiency virus (SIV)-infected rhesus monkeys against superinfection with a heterologous SIV isolate. Journal of Virology. 83: 2686-96. PMID 19129440 DOI: 10.1128/Jvi.02237-08  0.395
2009 Kong WP, Wu L, Wallstrom TC, Fischer W, Yang ZY, Ko SY, Letvin NL, Haynes BF, Hahn BH, Korber B, Nabel GJ. Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination. Journal of Virology. 83: 2201-15. PMID 19109395 DOI: 10.1128/Jvi.02256-08  0.481
2009 Basavapathruni A, Yeh W, Coffey R, Whitney J, Hraber P, Giri A, Rao S, Mascola J, Nabel G, Korber B, Seaman M, Letvin N. P04-41. Kinetics of antibody neutralization and viral evolution following envelope vaccination in SIV-infected rhesus monkeys Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P69  0.457
2009 Fischer W, Apetrei C, Hahn BH, Letvin NL, Nabel GJ, Korber BT. P20-21 LB. Gene-to-gene differences in evolutionary rate between HIV-1 and natural SIV from sooty mangabeys: Implications for vaccine tests in non-human primates Retrovirology. 6: P425. DOI: 10.1186/1742-4690-6-S3-P425  0.426
2009 Letvin N, Mascola J, Rao S, Buzby A, Roederer M, Hudgens M, Gilbert P, Seder R, Douek D, Koup R, Graham B, Nabel G. P19-57 LB. Gene-based vaccination protects against mucosal infection by a heterologous highly pathogenic SIV isolate in rhesus monkeys Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P421  0.429
2009 Hulot SL, Seaman MS, Dorosh LA, Korber BT, Letvin NL. P17-09. Immunization with a single HIV-1 envelope sequence can generate CD8+ T lymphocytes capable of recognizing multiple variant forms of envelope Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P291  0.503
2009 Yeh W, Rahman I, Hraber P, Giri A, Nevidomskyte D, Coffey R, Asmal M, Miljkovic S, Whitney J, Keele B, Shaw G, Korber B, Seaman, Letvin N. P03-07. Autologous neutralizing antibodies that select viral escape variants emerge late after SIV infection of rhesus monkeys. Retrovirology. 6: 24. DOI: 10.1186/1742-4690-6-S3-P24  0.371
2008 Zahn RC, Rett MD, Korioth-Schmitz B, Sun Y, Buzby AP, Goldstein S, Brown CR, Byrum RA, Freeman GJ, Letvin NL, Hirsch VM, Schmitz JE. Simian immunodeficiency virus (SIV)-specific CD8+ T-cell responses in vervet African green monkeys chronically infected with SIVagm. Journal of Virology. 82: 11577-88. PMID 18829748 DOI: 10.1128/JVI.01779-08  0.421
2008 Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, van Rooijen N, Hovav AH, Letvin NL. CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses. Blood. 112: 4585-90. PMID 18784371 DOI: 10.1182/Blood-2008-06-165803  0.714
2008 Santra S, Korber BT, Muldoon M, Barouch DH, Nabel GJ, Gao F, Hahn BH, Haynes BF, Letvin NL. A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys. Proceedings of the National Academy of Sciences of the United States of America. 105: 10489-94. PMID 18650391 DOI: 10.1073/Pnas.0803352105  0.567
2008 Sun Y, Santra S, Schmitz JE, Roederer M, Letvin NL. Magnitude and quality of vaccine-elicited T-cell responses in the control of immunodeficiency virus replication in rhesus monkeys. Journal of Virology. 82: 8812-9. PMID 18579590 DOI: 10.1128/JVI.00204-08  0.495
2008 Choi EI, Reimann KA, Letvin NL. In vivo natural killer cell depletion during primary simian immunodeficiency virus infection in rhesus monkeys. Journal of Virology. 82: 6758-61. PMID 18434394 DOI: 10.1128/JVI.02277-07  0.375
2008 Kim EY, Veazey RS, Zahn R, McEvers KJ, Baumeister SH, Foster GJ, Rett MD, Newberg MH, Kuroda MJ, Rieber EP, Piatak M, Lifson JD, Letvin NL, Wolinsky SM, Schmitz JE. Contribution of CD8+ T cells to containment of viral replication and emergence of mutations in Mamu-A*01-restricted epitopes in Simian immunodeficiency virus-infected rhesus monkeys. Journal of Virology. 82: 5631-5. PMID 18367519 DOI: 10.1128/Jvi.02749-07  0.425
2008 Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, Letvin NL. Kinetics of recombinant adenovirus type 5, vaccinia virus, modified vaccinia ankara virus, and DNA antigen expression in vivo and the induction of memory T-lymphocyte responses. Clinical and Vaccine Immunology : Cvi. 15: 691-6. PMID 18272665 DOI: 10.1128/Cvi.00418-07  0.686
2008 Fischer W, Liao HX, Haynes BF, Letvin NL, Korber B. Coping with viral diversity in HIV vaccine design: a response to Nickle et al. Plos Computational Biology. 4: e15; author reply e2. PMID 18225944 DOI: 10.1371/Journal.Pcbi.0040015  0.319
2008 Choi EI, Wang R, Peterson L, Letvin NL, Reimann KA. Use of an anti-CD16 antibody for in vivo depletion of natural killer cells in rhesus macaques. Immunology. 124: 215-22. PMID 18201184 DOI: 10.1111/j.1365-2567.2007.02757.x  0.335
2008 Sen P, Charini WA, Subbramanian RA, Manuel ER, Kuroda MJ, Autissier PA, Letvin NL. Clonal focusing of epitope-specific CD8+ T lymphocytes in rhesus monkeys following vaccination and simian-human immunodeficiency virus challenge. Journal of Virology. 82: 805-16. PMID 17977967 DOI: 10.1128/Jvi.01038-07  0.797
2007 Permar SR, Rao SS, Sun Y, Bao S, Buzby AP, Kang HH, Letvin NL. Clinical measles after measles virus challenge in simian immunodeficiency virus-infected measles virus-vaccinated rhesus monkeys. The Journal of Infectious Diseases. 196: 1784-93. PMID 18190259 DOI: 10.1086/522967  0.359
2007 Hovav AH, Panas MW, Rahman S, Sircar P, Gillard G, Cayabyab MJ, Letvin NL. Duration of antigen expression in vivo following DNA immunization modifies the magnitude, contraction, and secondary responses of CD8+ T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 179: 6725-33. PMID 17982062 DOI: 10.4049/Jimmunol.179.10.6725  0.777
2007 Letvin NL. Correlates of immune protection and the development of a human immunodeficiency virus vaccine. Immunity. 27: 366-9. PMID 17892845 DOI: 10.1016/j.immuni.2007.09.001  0.333
2007 Hovav AH, Panas MW, Osuna CE, Cayabyab MJ, Autissier P, Letvin NL. The impact of a boosting immunogen on the differentiation of secondary memory CD8+ T cells. Journal of Virology. 81: 12793-802. PMID 17881444 DOI: 10.1128/Jvi.01519-07  0.788
2007 Barker BR, Parvani JG, Meyer D, Hey AS, Skak K, Letvin NL. IL-21 induces apoptosis of antigen-specific CD8+ T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 179: 3596-603. PMID 17785794 DOI: 10.4049/Jimmunol.179.6.3596  0.787
2007 Letvin NL, Rao SS, Dang V, Buzby AP, Korioth-Schmitz B, Dombagoda D, Parvani JG, Clarke RH, Bar L, Carlson KR, Kozlowski PA, Hirsch VM, Mascola JR, Nabel GJ. No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys. Journal of Virology. 81: 12368-74. PMID 17686853 DOI: 10.1128/Jvi.00822-07  0.388
2007 Mo Y, Quanquin NM, Vecino WH, Ranganathan UD, Tesfa L, Bourn W, Derbyshire KM, Letvin NL, Jacobs WR, Fennelly GJ. Genetic alteration of Mycobacterium smegmatis to improve mycobacterium-mediated transfer of plasmid DNA into mammalian cells and DNA immunization. Infection and Immunity. 75: 4804-16. PMID 17664267 DOI: 10.1128/Iai.01877-06  0.312
2007 Qin L, Greenland JR, Moriya C, Cayabyab MJ, Letvin NL. Effects of type I interferons on the adjuvant properties of plasmid granulocyte-macrophage colony-stimulating factor in vivo. Journal of Virology. 81: 10606-13. PMID 17652387 DOI: 10.1128/Jvi.01000-07  0.672
2007 Seaman MS, Leblanc DF, Grandpre LE, Bartman MT, Montefiori DC, Letvin NL, Mascola JR. Standardized assessment of NAb responses elicited in rhesus monkeys immunized with single- or multi-clade HIV-1 envelope immunogens. Virology. 367: 175-86. PMID 17599382 DOI: 10.1016/j.virol.2007.05.024  0.397
2007 Santra S, Sun Y, Parvani JG, Philippon V, Wyand MS, Manson K, Gomez-Yafal A, Mazzara G, Panicali D, Markham PD, Montefiori DC, Letvin NL. Heterologous prime/boost immunization of rhesus monkeys by using diverse poxvirus vectors Journal of Virology. 81: 8563-8570. PMID 17553898 DOI: 10.1128/JVI.00744-07  0.438
2007 Sun Y, Permar SR, Buzby AP, Letvin NL. Memory CD4+ T-lymphocyte loss and dysfunction during primary simian immunodeficiency virus infection. Journal of Virology. 81: 8009-15. PMID 17522197 DOI: 10.1128/Jvi.00482-07  0.393
2007 Yu JS, Peacock JW, Jacobs WR, Frothingham R, Letvin NL, Liao HX, Haynes BF. Recombinant Mycobacterium bovis bacillus Calmette-Guerin elicits human immunodeficiency virus type 1 envelope-specific T lymphocytes at mucosal sites. Clinical and Vaccine Immunology : Cvi. 14: 886-93. PMID 17507541 DOI: 10.1128/Cvi.00407-06  0.375
2007 Greenland JR, Geiben R, Ghosh S, Pastor WA, Letvin NL. Plasmid DNA vaccine-elicited cellular immune responses limit in vivo vaccine antigen expression through Fas-mediated apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 178: 5652-8. PMID 17442948 DOI: 10.4049/Jimmunol.178.9.5652  0.653
2007 McCoy K, Tatsis N, Korioth-Schmitz B, Lasaro MO, Hensley SE, Lin SW, Li Y, Giles-Davis W, Cun A, Zhou D, Xiang Z, Letvin NL, Ertl HC. Effect of preexisting immunity to adenovirus human serotype 5 antigens on the immune responses of nonhuman primates to vaccine regimens based on human- or chimpanzee-derived adenovirus vectors. Journal of Virology. 81: 6594-604. PMID 17428852 DOI: 10.1128/Jvi.02497-06  0.423
2007 Greenland JR, Letvin NL. Chemical adjuvants for plasmid DNA vaccines. Vaccine. 25: 3731-41. PMID 17350735 DOI: 10.1016/J.Vaccine.2007.01.120  0.627
2007 Hasegawa A, Moriya C, Liu H, Charini WA, Vinet HC, Subbramanian RA, Sen P, Letvin NL, Kuroda MJ. Analysis of TCRalphabeta combinations used by simian immunodeficiency virus-specific CD8+ T cells in rhesus monkeys: implications for CTL immunodominance. Journal of Immunology (Baltimore, Md. : 1950). 178: 3409-17. PMID 17339435 DOI: 10.4049/Jimmunol.178.6.3409  0.444
2007 McKenna PM, Koser ML, Carlson KR, Montefiori DC, Letvin NL, Papaneri AB, Pomerantz RJ, Dietzschold B, Silvera P, McGettigan JP, Schnell MJ. Highly attenuated rabies virus-based vaccine vectors expressing simian-human immunodeficiency virus89.6P Env and simian immunodeficiency virusmac239 Gag are safe in rhesus macaques and protect from an AIDS-like disease. The Journal of Infectious Diseases. 195: 980-8. PMID 17330788 DOI: 10.1086/512243  0.417
2007 Demberg T, Florese RH, Heath MJ, Larsen K, Kalisz I, Kalyanaraman VS, Lee EM, Pal R, Venzon D, Grant R, Patterson LJ, Korioth-Schmitz B, Buzby A, Dombagoda D, Montefiori DC, ... Letvin NL, et al. A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques. Journal of Virology. 81: 3414-27. PMID 17229693 DOI: 10.1128/JVI.02453-06  0.315
2007 Fischer W, Perkins S, Theiler J, Bhattacharya T, Yusim K, Funkhouser R, Kuiken C, Haynes B, Letvin NL, Walker BD, Hahn BH, Korber BT. Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. Nature Medicine. 13: 100-6. PMID 17187074 DOI: 10.1038/Nm1461  0.309
2007 Huang D, Qiu L, Wang R, Lai X, Du G, Seghal P, Shen Y, Shao L, Halliday L, Fortman J, Shen L, Letvin NL, Chen ZW. Immune gene networks of mycobacterial vaccine-elicited cellular responses and immunity. The Journal of Infectious Diseases. 195: 55-69. PMID 17152009 DOI: 10.1086/509895  0.319
2007 Hovav AH, Cayabyab MJ, Panas MW, Santra S, Greenland J, Geiben R, Haynes BF, Jacobs WR, Letvin NL. Rapid memory CD8+ T-lymphocyte induction through priming with recombinant Mycobacterium smegmatis. Journal of Virology. 81: 74-83. PMID 17050608 DOI: 10.1128/Jvi.01269-06  0.842
2006 Letvin NL. Progress and obstacles in the development of an AIDS vaccine Nature Reviews Immunology. 6: 930-939. PMID 17124514 DOI: 10.1038/nri1959  0.376
2006 Manuel ER, Charini WA, Sen P, Peyerl FW, Kuroda MJ, Schmitz JE, Autissier P, Sheeter DA, Torbett BE, Letvin NL. Contribution of T-cell receptor repertoire breadth to the dominance of epitope-specific CD8+ T-lymphocyte responses. Journal of Virology. 80: 12032-40. PMID 17035327 DOI: 10.1128/Jvi.01479-06  0.837
2006 Yu JS, Peacock JW, Vanleeuwen S, Hsu T, Jacobs WR, Cayabyab MJ, Letvin NL, Frothingham R, Staats HF, Liao HX, Haynes BF. Generation of mucosal anti-human immunodeficiency virus type 1 T-cell responses by recombinant Mycobacterium smegmatis. Clinical and Vaccine Immunology : Cvi. 13: 1204-11. PMID 16943347 DOI: 10.1128/Cvi.00195-06  0.323
2006 Sun Y, Schmitz JE, Buzby AP, Barker BR, Rao SS, Xu L, Yang ZY, Mascola JR, Nabel GJ, Letvin NL. Virus-specific cellular immune correlates of survival in vaccinated monkeys after simian immunodeficiency virus challenge. Journal of Virology. 80: 10950-6. PMID 16943292 DOI: 10.1128/Jvi.01458-06  0.853
2006 Yeh WW, Cale EM, Jaru-Ampornpan P, Lord CI, Peyerl FW, Letvin NL. Compensatory substitutions restore normal core assembly in simian immunodeficiency virus isolates with Gag epitope cytotoxic T-lymphocyte escape mutations. Journal of Virology. 80: 8168-77. PMID 16873273 DOI: 10.1128/Jvi.00068-06  0.807
2006 Weaver EA, Lu Z, Camacho ZT, Moukdar F, Liao HX, Ma BJ, Muldoon M, Theiler J, Nabel GJ, Letvin NL, Korber BT, Hahn BH, Haynes BF, Gao F. Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen. Journal of Virology. 80: 6745-56. PMID 16809280 DOI: 10.1128/Jvi.02484-05  0.449
2006 Letvin NL, Mascola JR, Sun Y, Gorgone DA, Buzby AP, Xu L, Yang ZY, Chakrabarti B, Rao SS, Schmitz JE, Montefiori DC, Barker BR, Bookstein FL, Nabel GJ. Preserved CD4+ central memory T cells and survival in vaccinated SIV-challenged monkeys. Science (New York, N.Y.). 312: 1530-3. PMID 16763152 DOI: 10.1126/Science.1124226  0.838
2006 Du Pasquier RA, Stein MC, Lima MA, Dang X, Jean-Jacques J, Zheng Y, Letvin NL, Koralnik IJ. JC virus induces a vigorous CD8+ cytotoxic T cell response in multiple sclerosis patients. Journal of Neuroimmunology. 176: 181-6. PMID 16750575 DOI: 10.1016/j.jneuroim.2006.04.003  0.348
2006 Mattapallil JJ, Douek DC, Buckler-White A, Montefiori D, Letvin NL, Nabel GJ, Roederer M. Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge Journal of Experimental Medicine. 203: 1533-1541. PMID 16735692 DOI: 10.1084/Jem.20060657  0.423
2006 Subbramanian RA, Charini WA, Kuroda MJ, Seaman M, Chhay H, Lifton MA, Gorgone DA, Schmitz JE, Carville A, Letvin NL. Expansion after epitope peptide exposure in vitro predicts cytotoxic T lymphocyte epitope dominance hierarchy in lymphocytes of vaccinated mamu-a*01+ rhesus monkeys. Aids Research and Human Retroviruses. 22: 445-52. PMID 16706622 DOI: 10.1089/Aid.2006.22.445  0.398
2006 Acierno PM, Schmitz JE, Gorgone DA, Sun Y, Santra S, Seaman MS, Newberg MH, Mascola JR, Nabel GJ, Panicali D, Letvin NL. Preservation of functional virus-specific memory CD8+ T lymphocytes in vaccinated, simian human immunodeficiency virus-infected rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 176: 5338-45. PMID 16622001 DOI: 10.4049/Jimmunol.176.9.5338  0.441
2006 Pal R, Venzon D, Santra S, Kalyanaraman VS, Montefiori DC, Hocker L, Hudacik L, Rose N, Nacsa J, Edghill-Smith Y, Moniuszko M, Hel Z, Belyakov IM, Berzofsky JA, Parks RW, ... ... Letvin NL, et al. Systemic immunization with an ALVAC-HIV-1/protein boost vaccine strategy protects rhesus macaques from CD4+ T-cell loss and reduces both systemic and mucosal simian-human immunodeficiency virus SHIVKU2 RNA levels. Journal of Virology. 80: 3732-42. PMID 16571790 DOI: 10.1128/JVI.80.8.3732-3742.2006  0.444
2006 Xu R, Srivastava IK, Kuller L, Zarkikh I, Kraft Z, Fagrouch Z, Letvin NL, Heeney JL, Barnett SW, Stamatatos L. Immunization with HIV-1 SF162-derived Envelope gp140 proteins does not protect macaques from heterologous simian-human immunodeficiency virus SHIV89.6P infection. Virology. 349: 276-89. PMID 16527321 DOI: 10.1016/J.Virol.2006.01.043  0.32
2006 Cayabyab MJ, Hovav AH, Hsu T, Krivulka GR, Lifton MA, Gorgone DA, Fennelly GJ, Haynes BF, Jacobs WR, Letvin NL. Generation of CD8+ T-cell responses by a recombinant nonpathogenic Mycobacterium smegmatis vaccine vector expressing human immunodeficiency virus type 1 Env. Journal of Virology. 80: 1645-52. PMID 16439521 DOI: 10.1128/Jvi.80.4.1645-1652.2006  0.498
2006 Newberg MH, McEvers KJ, Gorgone DA, Lifton MA, Baumeister SHC, Veazey RS, Schmitz JE, Letvin NL. Immunodomination in the evolution of dominant epitope-specific CD8 + T lymphocyte responses in simian immunodeficiency virus-infected rhesus monkeys Journal of Immunology. 176: 319-328. PMID 16365424 DOI: 10.4049/jimmunol.176.1.319  0.469
2006 Rao SS, Gomez P, Mascola JR, Dang V, Krivulka GR, Yu F, Lord CI, Shen L, Bailer R, Nabel GJ, Letvin NL. Comparative evaluation of three different intramuscular delivery methods for DNA immunization in a nonhuman primate animal model. Vaccine. 24: 367-73. PMID 16194587 DOI: 10.1016/J.Vaccine.2005.07.072  0.341
2006 Letvin N. Virus-specific cellular immune correlates of survival in vaccinated monkeys after SIV challenge Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-S20  0.59
2005 Du G, Qiu L, Shen L, Sehgal P, Shen Y, Huang D, Letvin NL, Chen ZW. Combined megaplex TCR isolation and SMART-based real-time quantitation methods for quantitating antigen-specific T cell clones in mycobacterial infection. Journal of Immunological Methods. 308: 19-35. PMID 16403511 DOI: 10.1016/j.jim.2005.09.009  0.32
2005 Jackson SS, Schmitz JE, Kuroda MJ, McKay PF, Sumida SM, Martin KL, Yu F, Lifton MA, Gorgone DA, Letvin NL. Evaluation of CD62L expression as a marker for vaccine-elicited memory cytotoxic T lymphocytes. Immunology. 116: 443-53. PMID 16313358 DOI: 10.1111/j.1365-2567.2005.02243.x  0.433
2005 Peyerl FW, Barouch DH, Bazick HS, Manuel E, Letvin NL. Use of molecular beacons for rapid, real-time, quantitative monitoring of cytotoxic T-lymphocyte epitope mutations in simian immunodeficiency virus. Journal of Clinical Microbiology. 43: 4773-9. PMID 16145140 DOI: 10.1128/Jcm.43.9.4773-4779.2005  0.81
2005 Reimann KA, Parker RA, Seaman MS, Beaudry K, Beddall M, Peterson L, Williams KC, Veazey RS, Montefiori DC, Mascola JR, Nabel GJ, Letvin NL. Pathogenicity of simian-human immunodeficiency virus SHIV-89.6P and SIVmac is attenuated in cynomolgus macaques and associated with early T-lymphocyte responses. Journal of Virology. 79: 8878-85. PMID 15994781 DOI: 10.1128/Jvi.79.14.8878-8885.2005  0.355
2005 Barouch DH, Yang ZY, Kong WP, Korioth-Schmitz B, Sumida SM, Truitt DM, Kishko MG, Arthur JC, Miura A, Mascola JR, Letvin NL, Nabel GJ. A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates. Journal of Virology. 79: 8828-34. PMID 15994776 DOI: 10.1128/Jvi.79.14.8828-8834.2005  0.609
2005 Greenland JR, Liu H, Berry D, Anderson DG, Kim WK, Irvine DJ, Langer R, Letvin NL. Beta-amino ester polymers facilitate in vivo DNA transfection and adjuvant plasmid DNA immunization. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 164-70. PMID 15963932 DOI: 10.1016/J.Ymthe.2005.01.021  0.587
2005 Schmitz JE, Johnson RP, McClure HM, Manson KH, Wyand MS, Kuroda MJ, Lifton MA, Khunkhun RS, McEvers KJ, Gillis J, Piatak M, Lifson JD, Grosschupff G, Racz P, Tenner-Racz K, ... ... Letvin NL, et al. Effect of CD8+ lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239delta3-vaccinated rhesus macaques. Journal of Virology. 79: 8131-41. PMID 15956558 DOI: 10.1128/Jvi.79.13.8131-8141.2005  0.458
2005 Jackson SS, Ilyinskii P, Philippon V, Gritz L, Yafal AG, Zinnack K, Beaudry KR, Manson KH, Lifton MA, Kuroda MJ, Letvin NL, Mazzara GP, Panicali DL. Role of genes that modulate host immune responses in the immunogenicity and pathogenicity of vaccinia virus. Journal of Virology. 79: 6554-9. PMID 15858042 DOI: 10.1128/JVI.79.10.6554-6559.2005  0.339
2005 Santra S, Seaman MS, Xu L, Barouch DH, Lord CI, Lifton MA, Gorgone DA, Beaudry KR, Svehla K, Welcher B, Chakrabarti BK, Huang Y, Yang ZY, Mascola JR, Nabel GJ, ... Letvin NL, et al. Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. Journal of Virology. 79: 6516-22. PMID 15858035 DOI: 10.1128/Jvi.79.10.6516-6522.2005  0.576
2005 Sun Y, Schmitz JE, Acierno PM, Santra S, Subbramanian RA, Barouch DH, Gorgone DA, Lifton MA, Beaudry KR, Manson K, Philippon V, Xu L, Maecker HT, Mascola JR, Panicali D, ... ... Letvin NL, et al. Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 174: 4753-60. PMID 15814700 DOI: 10.4049/Jimmunol.174.8.4753  0.626
2005 Seaman MS, Santra S, Newberg MH, Philippon V, Manson K, Xu L, Gelman RS, Panicali D, Mascola JR, Nabel GJ, Letvin NL. Vaccine-elicited memory cytotoxic T lymphocytes contribute to Mamu-A*01-associated control of simian/human immunodeficiency virus 89.6P replication in rhesus monkeys. Journal of Virology. 79: 4580-8. PMID 15795244 DOI: 10.1128/Jvi.79.8.4580-4588.2005  0.463
2005 Hershberger KL, Kurian J, Korber BT, Letvin NL. Killer cell immunoglobulin-like receptors (KIR) of the African-origin sabaeus monkey: evidence for recombination events in the evolution of KIR. European Journal of Immunology. 35: 922-35. PMID 15714591 DOI: 10.1002/Eji.200425408  0.772
2005 Seaman MS, Xu L, Beaudry K, Martin KL, Beddall MH, Miura A, Sambor A, Chakrabarti BK, Huang Y, Bailer R, Koup RA, Mascola JR, Nabel GJ, Letvin NL. Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys. Journal of Virology. 79: 2956-63. PMID 15709015 DOI: 10.1128/Jvi.79.5.2956-2963.2005  0.427
2005 Barouch DH, Powers J, Truitt DM, Kishko MG, Arthur JC, Peyerl FW, Kuroda MJ, Gorgone DA, Lifton MA, Lord CI, Hirsch VM, Montefiori DC, Carville A, Mansfield KG, Kunstman KJ, ... ... Letvin NL, et al. Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants. Nature Immunology. 6: 247-52. PMID 15685174 DOI: 10.1038/Ni1167  0.781
2005 Letvin NL. Progress toward an HIV vaccine Annual Review of Medicine. 56: 213-223. PMID 15660510 DOI: 10.1146/annurev.med.54.101601.152349  0.331
2005 Johnson PR, Schnepp BC, Connell MJ, Rohne D, Robinson S, Krivulka GR, Lord CI, Zinn R, Montefiori DC, Letvin NL, Clark KR. Novel adeno-associated virus vector vaccine restricts replication of simian immunodeficiency virus in macaques. Journal of Virology. 79: 955-65. PMID 15613324 DOI: 10.1128/JVI.79.2.955-965.2005  0.407
2005 Mascola JR, Sambor A, Beaudry K, Santra S, Welcher B, Louder MK, Vancott TC, Huang Y, Chakrabarti BK, Kong WP, Yang ZY, Xu L, Montefiori DC, Nabel GJ, Letvin NL. Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins. Journal of Virology. 79: 771-9. PMID 15613305 DOI: 10.1128/Jvi.79.2.771-779.2005  0.337
2005 Barouch D, Letvin N, Havenga M, Goudsmit J. Novel Adenovirus Vector-Based Vaccines for HIV Retrovirology. 2: 1-1. DOI: 10.1186/1742-4690-2-S1-S60  0.383
2004 Price DA, West SM, Betts MR, Ruff LE, Brenchley JM, Ambrozak DR, Edghill-Smith Y, Kuroda MJ, Bogdan D, Kunstman K, Letvin NL, Franchini G, Wolinsky SM, Koup RA, Douek DC. T cell receptor recognition motifs govern immune escape patterns in acute SIV infection. Immunity. 21: 793-803. PMID 15589168 DOI: 10.1016/J.Immuni.2004.10.010  0.48
2004 Shen Y, Shen L, Sehgal P, Huang D, Qiu L, Du G, Letvin NL, Chen ZW. Clinical latency and reactivation of AIDS-related mycobacterial infections. Journal of Virology. 78: 14023-32. PMID 15564509 DOI: 10.1128/JVI.78.24.14023-14032.2004  0.31
2004 Peyerl FW, Bazick HS, Newberg MH, Barouch DH, Sodroski J, Letvin NL. Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope. Journal of Virology. 78: 13901-10. PMID 15564498 DOI: 10.1128/Jvi.78.24.13901-13910.2004  0.754
2004 Barouch DH, Letvin NL, Seder RA. The role of cytokine DNAs as vaccine adjuvants for optimizing cellular immune responses Immunological Reviews. 202: 266-274. PMID 15546399 DOI: 10.1111/j.0105-2896.2004.00200.x  0.555
2004 Peacock JW, Nordone SK, Jackson SS, Liao HX, Letvin NL, Yafal AG, Gritz L, Mazzara GP, Haynes BF, Staats HF. Gender differences in human immunodeficiency virus type 1-specific CD8 responses in the reproductive tract and colon following nasal peptide priming and modified vaccinia virus Ankara boosting. Journal of Virology. 78: 13163-72. PMID 15542668 DOI: 10.1128/JVI.78.23.13163-13172.2004  0.365
2004 Sumida SM, McKay PF, Truitt DM, Kishko MG, Arthur JC, Seaman MS, Jackson SS, Gorgone DA, Lifton MA, Letvin NL, Barouch DH. Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines. The Journal of Clinical Investigation. 114: 1334-42. PMID 15520866 DOI: 10.1172/Jci22608  0.562
2004 Subbramanian RA, Moriya C, Martin KL, Peyerl FW, Hasegawa A, Naoi A, Chhay H, Autissier P, Gorgone DA, Lifton MA, Kuus-Reichel K, Schmitz JE, Letvin NL, Kuroda MJ. Engineered T-cell receptor tetramers bind MHC-peptide complexes with high affinity. Nature Biotechnology. 22: 1429-34. PMID 15502816 DOI: 10.1038/nbt1024  0.679
2004 Kim WK, Corey S, Chesney G, Knight H, Klumpp S, Wüthrich C, Letvin N, Koralnik I, Lackner A, Veasey R, Williams K. Identification of T lymphocytes in simian immunodeficiency virus encephalitis: distribution of CD8+ T cells in association with central nervous system vessels and virus. Journal of Neurovirology. 10: 315-25. PMID 15385254 DOI: 10.1080/13550280490505382  0.414
2004 Shen L, Shen Y, Huang D, Qiu L, Sehgal P, Du GZ, Miller MD, Letvin NL, Chen ZW. Development of Vgamma2Vdelta2+ T cell responses during active mycobacterial coinfection of simian immunodeficiency virus-infected macaques requires control of viral infection and immune competence of CD4+ T cells. The Journal of Infectious Diseases. 190: 1438-47. PMID 15378436 DOI: 10.1086/423939  0.427
2004 Du Pasquier RA, Schmitz JE, Jean-Jacques J, Zheng Y, Gordon J, Khalili K, Letvin NL, Koralnik IJ. Detection of JC virus-specific cytotoxic T lymphocytes in healthy individuals. Journal of Virology. 78: 10206-10. PMID 15331755 DOI: 10.1128/Jvi.78.18.10206-10210.2004  0.369
2004 Barouch DH, Truitt DM, Letvin NL. Expression kinetics of the interleukin-2/immunoglobulin (IL-2/Ig) plasmid cytokine adjuvant Vaccine. 22: 3092-3097. PMID 15297060 DOI: 10.1016/j.vaccine.2004.01.065  0.543
2004 Permar SR, Klumpp SA, Mansfield KG, Carville AA, Gorgone DA, Lifton MA, Schmitz JE, Reimann KA, Polack FP, Griffin DE, Letvin NL. Limited contribution of humoral immunity to the clearance of measles viremia in rhesus monkeys. The Journal of Infectious Diseases. 190: 998-1005. PMID 15295708 DOI: 10.1086/422846  0.423
2004 Peyerl FW, Barouch DH, Letvin NL. Structural constraints on viral escape from HIV- and SIV-specific cytotoxic T-lymphocytes. Viral Immunology. 17: 144-51. PMID 15279695 DOI: 10.1089/0882824041310658  0.784
2004 Santra S, Barouch DH, Korioth-Schmitz B, Lord CI, Krivulka GR, Yu F, Beddall MH, Gorgone DA, Lifton MA, Miura A, Philippon V, Manson K, Markham PD, Parrish J, Kuroda MJ, ... ... Letvin NL, et al. Recombinant poxvirus boosting of DNA-primed rhesus monkeys augments peak but not memory T lymphocyte responses. Proceedings of the National Academy of Sciences of the United States of America. 101: 11088-93. PMID 15258286 DOI: 10.1073/Pnas.0401954101  0.632
2004 Barouch DH, Letvin NL. HIV escape from cytotoxic T lymphocytes: A potential hurdle for vaccines? Lancet. 364: 10-11. PMID 15234837 DOI: 10.1016/S0140-6736(04)16609-9  0.554
2004 Letvin NL, Huang Y, Chakrabarti BK, Xu L, Seaman MS, Beaudry K, Korioth-Schmitz B, Yu F, Rohne D, Martin KL, Miura A, Kong WP, Yang ZY, Gelman RS, Golubeva OG, et al. Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys. Journal of Virology. 78: 7490-7. PMID 15220422 DOI: 10.1128/Jvi.78.14.7490-7497.2004  0.447
2004 Haigwood NL, Montefiori DC, Sutton WF, McClure J, Watson AJ, Voss G, Hirsch VM, Richardson BA, Letvin NL, Hu SL, Johnson PR. Passive immunotherapy in simian immunodeficiency virus-infected macaques accelerates the development of neutralizing antibodies. Journal of Virology. 78: 5983-95. PMID 15140996 DOI: 10.1128/Jvi.78.11.5983-5995.2004  0.328
2004 Barouch DH, Pau MG, Custers JH, Koudstaal W, Kostense S, Havenga MJ, Truitt DM, Sumida SM, Kishko MG, Arthur JC, Korioth-Schmitz B, Newberg MH, Gorgone DA, Lifton MA, Panicali DL, ... ... Letvin NL, et al. Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity. Journal of Immunology (Baltimore, Md. : 1950). 172: 6290-7. PMID 15128818 DOI: 10.4049/Jimmunol.172.10.6290  0.502
2004 Mattapallil JJ, Letvin NL, Roederer M. T-cell dynamics during acute SIV infection Aids. 18: 13-23. PMID 15090825 DOI: 10.1097/00002030-200401020-00002  0.334
2004 McKay PF, Barouch DH, Santra S, Sumida SM, Jackson SS, Gorgone DA, Lifton MA, Letvin NL. Recruitment of different subsets of antigen-presenting cells selectively modulates DNA vaccine-elicited CD4+ and CD8+ T lymphocyte responses European Journal of Immunology. 34: 1011-1020. PMID 15048711 DOI: 10.1002/eji.200324840  0.617
2004 Malkevitch N, Rohne D, Pinczewski J, Aldrich K, Kalyanaraman VS, Letvin NL, Robert-Guroff M. Evaluation of combination DNA/replication-competent Ad-SIV recombinant immunization regimens in rhesus macaques. Aids Research and Human Retroviruses. 20: 235-44. PMID 15018712 DOI: 10.1089/088922204773004969  0.365
2004 Cayabyab M, Rohne D, Pollakis G, Mische C, Messele T, Abebe A, Etemad-Moghadam B, Yang P, Henson S, Axthelm M, Goudsmit J, Letvin NL, Sodroski J. Rapid CD4+ T-lymphocyte depletion in rhesus monkeys infected with a simian-human immunodeficiency virus expressing the envelope glycoproteins of a primary dual-tropic Ethiopian Clade C HIV type 1 isolate. Aids Research and Human Retroviruses. 20: 27-40. PMID 15000696 DOI: 10.1089/088922204322749477  0.396
2004 Sumida SM, Truitt DM, Kishko MG, Arthur JC, Jackson SS, Gorgone DA, Lifton MA, Koudstaal W, Pau MG, Kostense S, Havenga MJ, Goudsmit J, Letvin NL, Barouch DH. Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. Journal of Virology. 78: 2666-73. PMID 14990686 DOI: 10.1128/Jvi.78.6.2666-2673.2004  0.562
2004 Hirsch VM, Santra S, Goldstein S, Plishka R, Buckler-White A, Seth A, Ourmanov I, Brown CR, Engle R, Montefiori D, Glowczwskie J, Kunstman K, Wolinsky S, Letvin NL. Immune failure in the absence of profound CD4+ T-lymphocyte depletion in simian immunodeficiency virus-infected rapid progressor macaques. Journal of Virology. 78: 275-84. PMID 14671109 DOI: 10.1128/JVI.78.1.275-284.2004  0.437
2004 Seaman MS, Peyerl FW, Jackson SS, Lifton MA, Gorgone DA, Schmitz JE, Letvin NL. Subsets of memory cytotoxic T lymphocytes elicited by vaccination influence the efficiency of secondary expansion in vivo. Journal of Virology. 78: 206-15. PMID 14671102 DOI: 10.1128/JVI.78.1.206-215.2004  0.768
2004 Pasquier RD, Kuroda M, Schmitz J, Jean-Jacques J, Zheng Y, Letvin N, Koralnik I. The cellular immune response against JC virus is instrumental in the containment of progressive multifocal leukoencephalopathy Journal of Neurovirology. 10: 30-30. DOI: 10.1080/13550280490469734  0.423
2003 Peyerl FW, Barouch DH, Yeh WW, Bazick HS, Kunstman J, Kunstman KJ, Wolinsky SM, Letvin NL. Simian-human immunodeficiency virus escape from cytotoxic T-lymphocyte recognition at a structurally constrained epitope. Journal of Virology. 77: 12572-8. PMID 14610180 DOI: 10.1128/JVI.77.23.12572-12578.2003  0.768
2003 Gao F, Li Y, Decker JM, Peyerl FW, Bibollet-Ruche F, Rodenburg CM, Chen Y, Shaw DR, Allen S, Musonda R, Shaw GM, Zajac AJ, Letvin N, Hahn BH. Codon usage optimization of HIV type 1 subtype C gag, pol, env, and nef genes: in vitro expression and immune responses in DNA-vaccinated mice. Aids Research and Human Retroviruses. 19: 817-23. PMID 14585212 DOI: 10.1089/088922203769232610  0.751
2003 Du Pasquier RA, Kuroda MJ, Schmitz JE, Zheng Y, Martin K, Peyerl FW, Lifton M, Gorgone D, Autissier P, Letvin NL, Koralnik IJ. Low frequency of cytotoxic T lymphocytes against the novel HLA-A*0201-restricted JC virus epitope VP1(p36) in patients with proven or possible progressive multifocal leukoencephalopathy. Journal of Virology. 77: 11918-26. PMID 14581528 DOI: 10.1128/Jvi.77.22.11918-11926.2003  0.715
2003 Mascola JR, Lewis MG, VanCott TC, Stiegler G, Katinger H, Seaman M, Beaudry K, Barouch DH, Korioth-Schmitz B, Krivulka G, Sambor A, Welcher B, Douek DC, Montefiori DC, Shiver JW, ... ... Letvin NL, et al. Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies. Journal of Virology. 77: 10348-56. PMID 12970419 DOI: 10.1128/JVI.77.19.10348-10356.2003  0.602
2003 Subbramanian RA, Kuroda MJ, Charini WA, Barouch DH, Costantino C, Santra S, Schmitz JE, Martin KL, Lifton MA, Gorgone DA, Shiver JW, Letvin NL. Magnitude and diversity of cytotoxic-T-lymphocyte responses elicited by multiepitope DNA vaccination in rhesus monkeys. Journal of Virology. 77: 10113-8. PMID 12941922 DOI: 10.1128/JVI.77.18.10113-10118.2003  0.6
2003 Barouch DH, McKay PF, Sumida SM, Santra S, Jackson SS, Gorgone DA, Lifton MA, Chakrabarti BK, Xu L, Nabel GJ, Letvin NL. Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines. Journal of Virology. 77: 8729-35. PMID 12885892 DOI: 10.1128/Jvi.77.16.8729-8735.2003  0.594
2003 Lai X, Shen Y, Zhou D, Sehgal P, Shen L, Simon M, Qiu L, Letvin NL, Chen ZW. Immune biology of macaque lymphocyte populations during mycobacterial infection. Clinical and Experimental Immunology. 133: 182-92. PMID 12869023 DOI: 10.1046/j.1365-2249.2003.02209.x  0.408
2003 Letvin NL, Walker BD. Immunopathogenesis and immunotherapy in AIDS virus infections Nature Medicine. 9: 861-866. PMID 12835706 DOI: 10.1038/nm0703-861  0.311
2003 Barouch DH, Kunstman J, Glowczwskie J, Kunstman KJ, Egan MA, Peyerl FW, Santra S, Kuroda MJ, Schmitz JE, Beaudry K, Krivulka GR, Lifton MA, Gorgone DA, Wolinsky SM, Letvin NL. Viral escape from dominant simian immunodeficiency virus epitope-specific cytotoxic T lymphocytes in DNA-vaccinated rhesus monkeys. Journal of Virology. 77: 7367-75. PMID 12805435 DOI: 10.1128/JVI.77.13.7367-7375.2003  0.804
2003 Chen ZW, Letvin NL. Vγ2Vδ2+ T cells and anti-microbial immune responses Microbes and Infection. 5: 491-498. PMID 12758278 DOI: 10.1016/S1286-4579(03)00074-1  0.337
2003 Chen ZW, Letvin NL. Adaptive immune response of Vγ2Vδ2 T cells: A new paradigm Trends in Immunology. 24: 213-219. PMID 12697454 DOI: 10.1016/S1471-4906(03)00032-2  0.34
2003 Premenko-Lanier M, Rota PA, Rhodes G, Verhoeven D, Barouch DH, Lerche NW, Letvin NL, Bellini WJ, McChesney MB. DNA vaccination of infants in the presence of maternal antibody: a measles model in the primate. Virology. 307: 67-75. PMID 12667815 DOI: 10.1016/S0042-6822(02)00036-3  0.535
2003 McKay PF, Barouch DH, Schmitz JE, Veazey RS, Gorgone DA, Lifton MA, Williams KC, Letvin NL. Global dysfunction of CD4 T-lymphocyte cytokine expression in simian-human immunodeficiency virus/SIV-infected monkeys is prevented by vaccination Journal of Virology. 77: 4695-4702. PMID 12663776 DOI: 10.1128/JVI.77.8.4695-4702.2003  0.623
2003 Permar SR, Klumpp SA, Mansfield KG, Kim WK, Gorgone DA, Lifton MA, Williams KC, Schmitz JE, Reimann KA, Axthelm MK, Polack FP, Griffin DE, Letvin NL. Role of CD8(+) lymphocytes in control and clearance of measles virus infection of rhesus monkeys. Journal of Virology. 77: 4396-400. PMID 12634396 DOI: 10.1128/Jvi.77.7.4396-4400.2003  0.442
2003 Schmollinger JC, Vonderheide RH, Hoar KM, Maecker B, Schultze JL, Hodi FS, Soiffer RJ, Jung K, Kuroda MJ, Letvin NL, Greenfield EA, Mihm M, Kutok JL, Dranoff G. Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction. Proceedings of the National Academy of Sciences of the United States of America. 100: 3398-403. PMID 12626761 DOI: 10.1073/Pnas.0530311100  0.315
2003 Zhou D, Lai X, Shen Y, Sehgal P, Shen L, Simon M, Qiu L, Huang D, Du GZ, Wang Q, Letvin NL, Chen ZW. Inhibition of adaptive Vgamma2Vdelta2+ T-cell responses during active mycobacterial coinfection of simian immunodeficiency virus SIVmac-infected monkeys. Journal of Virology. 77: 2998-3006. PMID 12584325 DOI: 10.1128/JVI.77.5.2998-3006.2003  0.404
2003 Schmitz JE, Kuroda MJ, Santra S, Simon MA, Lifton MA, Lin W, Khunkhun R, Piatak M, Lifson JD, Grosschupff G, Gelman RS, Racz P, Tenner-Racz K, Mansfield KA, Letvin NL, et al. Effect of humoral immune responses on controlling viremia during primary infection of rhesus monkeys with simian immunodeficiency virus. Journal of Virology. 77: 2165-73. PMID 12525651 DOI: 10.1128/JVI.77.3.2165-2173.2003  0.353
2003 Choi EI, Letvin NL. AIDS Vaccines: Challenges and Prospects The Vaccine Book. 245-255. DOI: 10.1016/B978-012107258-2/50020-2  0.3
2002 Barouch DH, Letvin NL. Viral evolution and challenges in the development of HIV vaccines Vaccine. 20. PMID 12477431 DOI: 10.1016/S0264-410X(02)00390-0  0.613
2002 Baig J, Levy DB, McKay PF, Schmitz JE, Santra S, Subbramanian RA, Kuroda MJ, Lifton MA, Gorgone DA, Wyatt LS, Moss B, Huang Y, Chakrabarti BK, Xu L, Kong WP, ... ... Letvin NL, et al. Elicitation of simian immunodeficiency virus-specific cytotoxic T lymphocytes in mucosal compartments of rhesus monkeys by systemic vaccination. Journal of Virology. 76: 11484-90. PMID 12388710 DOI: 10.1128/Jvi.76.22.11484-11490.2002  0.454
2002 Newberg MH, Kuroda MJ, Charini WA, Miura A, Lord CI, Schmitz JE, Gorgone DA, Lifton MA, Kuus-Reichel K, Letvin NL. A simian immunodeficiency virus nef peptide is a dominant cytotoxic T lymphocyte epitope in Indian-origin rhesus monkeys expressing the common MHC class I allele mamu-A*02. Virology. 301: 365-73. PMID 12359438 DOI: 10.1006/viro.2002.1598  0.477
2002 Santra S, Barouch DH, Kuroda MJ, Schmitz JE, Krivulka GR, Beaudry K, Lord CI, Lifton MA, Wyatt LS, Moss B, Hirsch VM, Letvin NL. Prior vaccination increases the epitopic breadth of the cytotoxic T-lymphocyte response that evolves in rhesus monkeys following a simian-human immunodeficiency virus infection. Journal of Virology. 76: 6376-81. PMID 12021371 DOI: 10.1128/Jvi.76.12.6376-6381.2002  0.632
2002 Etemad-Moghadam B, Rhone D, Steenbeke T, Sun Y, Manola J, Gelman R, Fanton JW, Racz P, Tenner-Racz K, Axthelm MK, Letvin NL, Sodroski J. Understanding the basis of CD4(+) T-cell depletion in macaques infected by a simian-human immunodeficiency virus. Vaccine. 20: 1934-7. PMID 11983249 DOI: 10.1016/S0264-410X(02)00072-5  0.441
2002 Rasmussen RA, Hofmann-Lehmann R, Li PL, Vlasak J, Schmitz JE, Reimann KA, Kuroda MJ, Letvin NL, Montefiori DC, McClure HM, Ruprecht RM. Neutralizing antibodies as a potential secondary protective mechanism during chronic SHIV infection in CD8+ T-cell-depleted macaques. Aids (London, England). 16: 829-38. PMID 11919484 DOI: 10.1097/00002030-200204120-00002  0.436
2002 Shen Y, Zhou D, Qiu L, Lai X, Simon M, Shen L, Kou Z, Wang Q, Jiang L, Estep J, Hunt R, Clagett M, Sehgal PK, Li Y, Zeng X, ... ... Letvin NL, et al. Adaptive immune response of Vgamma2Vdelta2+ T cells during mycobacterial infections. Science (New York, N.Y.). 295: 2255-8. PMID 11910108 DOI: 10.1126/Science.1068819  0.383
2002 Letvin NL, Barouch DH, Montefiori DC. Prospects for vaccine protection against HIV-1 infection and AIDS Annual Review of Immunology. 20: 73-99. PMID 11861598 DOI: 10.1146/annurev.immunol.20.081501.094854  0.549
2002 Santra S, Schmitz JE, Kuroda MJ, Lifton MA, Nickerson CE, Lord CI, Pal R, Franchini G, Letvin NL. Recombinant canarypox vaccine-elicited CTL specific for dominant and subdominant simian immunodeficiency virus epitopes in rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 168: 1847-53. PMID 11823518 DOI: 10.4049/jimmunol.168.4.1847  0.427
2002 Barouch DH, Kunstman J, Kuroda MJ, Schmitz JE, Santra S, Peyerl FW, Krivulka GR, Beaudry K, Lifton MA, Gorgone DA, Montefiori DC, Lewis MG, Wolinsky SM, Letvin NL. Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes. Nature. 415: 335-9. PMID 11797012 DOI: 10.1038/415335a  0.797
2002 Shiver JW, Fu TM, Chen L, Casimiro DR, Davies ME, Evans RK, Zhang ZQ, Simon AJ, Trigona WL, Dubey SA, Huang L, Harris VA, Long RS, Liang X, Handt L, ... ... Letvin NL, et al. Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity. Nature. 415: 331-5. PMID 11797011 DOI: 10.1038/415331a  0.414
2002 Barouch DH, Santra S, Tenner-Racz K, Racz P, Kuroda MJ, Schmitz JE, Jackson SS, Lifton MA, Freed DC, Perry HC, Davies ME, Shiver JW, Letvin NL. Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CSF. Journal of Immunology (Baltimore, Md. : 1950). 168: 562-8. PMID 11777947 DOI: 10.4049/jimmunol.168.2.562  0.634
2002 McKay PF, Schmitz JE, Barouch DH, Kuroda MJ, Lifton MA, Nickerson CE, Gorgone DA, Letvin NL. Vaccine protection against functional CTL abnormalities in simian human immunodeficiency virus-infected rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 168: 332-7. PMID 11751978 DOI: 10.4049/jimmunol.168.1.332  0.572
2002 Pal R, Venzon D, Letvin NL, Santra S, Montefiori DC, Miller NR, Tryniszewska E, Lewis MG, VanCott TC, Hirsch V, Woodward R, Gibson A, Grace M, Dobratz E, Markham PD, et al. ALVAC-SIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiency Journal of Virology. 76: 292-302. PMID 11739694 DOI: 10.1128/Jvi.76.1.292-302.2002  0.509
2001 LaBonte ML, Hershberger KL, Korber B, Letvin NL. The KIR and CD94/NKG2 families of molecules in the rhesus monkey. Immunological Reviews. 183: 25-40. PMID 11782245 DOI: 10.1034/J.1600-065X.2001.1830103.X  0.786
2001 Schmitz JE, Veazey RS, Kuroda MJ, Levy DB, Seth A, Mansfield KG, Nickerson CE, Lifton MA, Alvarez X, Lackner AA, Letvin NL. Simian immunodeficiency virus (SIV)-specific cytotoxic T lymphocytes in gastrointestinal tissues of chronically SIV-infected rhesus monkeys. Blood. 98: 3757-61. PMID 11739183 DOI: 10.1182/blood.V98.13.3757  0.339
2001 Hel Z, Nacsa J, Kelsall B, Tsai WP, Letvin N, Parks RW, Tryniszewska E, Picker L, Lewis MG, Edghill-Smith Y, Moniuszko M, Pal R, Stevceva L, Altman JD, Allen TM, et al. Impairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques. Journal of Virology. 75: 11483-95. PMID 11689630 DOI: 10.1128/Jvi.75.23.11483-11495.2001  0.536
2001 Charini WA, Kuroda MJ, Schmitz JE, Beaudry KR, Lin W, Lifton MA, Krivulka GR, Necker A, Letvin NL. Clonally diverse CTL response to a dominant viral epitope recognizes potential epitope variants Journal of Immunology. 167: 4996-5003. PMID 11673507 DOI: 10.4049/jimmunol.167.9.4996  0.397
2001 Barouch DH, Fu TM, Montefiori DC, Lewis MG, Shiver JW, Letvin NL. Vaccine-elicited immune responses prevent clinical AIDS in SHIV(89.6P)-infected rhesus monkeys. Immunology Letters. 79: 57-61. PMID 11595290 DOI: 10.1016/S0165-2478(01)00266-8  0.434
2001 Robinson S, Charini WA, Newberg MH, Kuroda MJ, Lord CI, Letvin NL. A commonly recognized simian immunodeficiency virus Nef epitope presented to cytotoxic T lymphocytes of Indian-origin rhesus monkeys by the prevalent major histocompatibility complex class I allele Mamu-A*02. Journal of Virology. 75: 10179-86. PMID 11581386 DOI: 10.1128/Jvi.75.21.10179-10186.2001  0.485
2001 Shen Y, Shen L, Sehgal P, Zhou D, Simon M, Miller M, Enimi EA, Henckler B, Chalifoux L, Sehgal N, Gastron M, Letvin NL, Chen ZW. Antiretroviral agents restore Mycobacterium-specific T-cell immune responses and facilitate controlling a fatal tuberculosis-like disease in Macaques coinfected with simian immunodeficiency virus and Mycobacterium bovis BCG. Journal of Virology. 75: 8690-6. PMID 11507214 DOI: 10.1128/JVI.75.18.8690-8696.2001  0.349
2001 Barouch DH, Letvin NL. CD8+ cytotoxic T lymphocyte responses to lentiviruses and herpesviruses Current Opinion in Immunology. 13: 479-482. PMID 11498305 DOI: 10.1016/S0952-7915(00)00244-2  0.387
2001 Craiu A, Frost JD, Reimann KA, Strom TB, Letvin NL, Barouch DH, Xin Xiao Zheng, Kuroda MJ, Schmitz JE, Lifton MA, Steenbeke TD, Nickerson CE, Beaudry K. An IL-2/Ig fusion protein influences CD4+ T lymphocytes in naive and simian immunodeficiency virus-infected rhesus monkeys Aids Research and Human Retroviruses. 17: 873-886. PMID 11461674 DOI: 10.1089/088922201750290005  0.308
2001 Etemad-Moghadam B, Rhone D, Steenbeke T, Sun Y, Manola J, Gelman R, Fanton JW, Racz P, Tenner-Racz K, Axthelm MK, Letvin NL, Sodroski J. Membrane-fusing capacity of the human immunodeficiency virus envelope proteins determines the efficiency of CD+ T-cell depletion in macaques infected by a simian-human immunodeficiency virus. Journal of Virology. 75: 5646-55. PMID 11356972 DOI: 10.1128/Jvi.75.12.5646-5655.2001  0.42
2001 Barouch DH, Santra S, Kuroda MJ, Schmitz JE, Plishka R, Buckler-White A, Gaitan AE, Zin R, Nam JH, Wyatt LS, Lifton MA, Nickerson CE, Moss B, Montefiori DC, Hirsch VM, ... Letvin NL, et al. Reduction of simian-human immunodeficiency virus 89.6P viremia in rhesus monkeys by recombinant modified vaccinia virus Ankara vaccination. Journal of Virology. 75: 5151-8. PMID 11333896 DOI: 10.1128/Jvi.75.11.5151-5158.2001  0.475
2001 Chen ZW, Shen Y, Zhou D, Simon M, Kou Z, Lee-Parritz D, Shen L, Sehgal P, Letvin NL. In vivo T-lymphocyte activation and transient reduction of viral replication in macaques infected with simian immunodeficiency virus. Journal of Virology. 75: 4713-20. PMID 11312343 DOI: 10.1128/JVI.75.10.4713-4720.2001  0.387
2001 Letvin NL, Robinson S, Rohne D, Axthelm MK, Fanton JW, Bilska M, Palker TJ, Liao HX, Haynes BF, Montefiori DC. Vaccine-elicited V3 loop-specific antibodies in rhesus monkeys and control of a simian-human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate envelope. Journal of Virology. 75: 4165-75. PMID 11287566 DOI: 10.1128/JVI.75.9.4165-4175.2001  0.389
2001 Chen ZW, Li Y, Zeng X, Kuroda MJ, Schmitz JE, Shen Y, Lai X, Shen L, Letvin NL. The TCR repertoire of an immunodominant CD8+ T lymphocyte population Journal of Immunology. 166: 4525-4533. PMID 11254709 DOI: 10.4049/jimmunol.166.7.4525  0.402
2001 Hershberger KL, Shyam R, Miura A, Letvin NL. Diversity of the killer cell Ig-like receptors of rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 166: 4380-90. PMID 11254692 DOI: 10.4049/Jimmunol.166.7.4380  0.761
2001 Huete JMB, Chatis PA, Schmitz JE, Kuroda MJ, Letvin NL, Reimann KA. Detection of viral RNA in CD4-CD8- and CD4-CD8+ lymphocytes in vivo in rhesus monkeys infected with simian immunodeficiency virus of macaques Aids Research and Human Retroviruses. 17: 349-360. PMID 11242521 DOI: 10.1089/08892220150503717  0.313
2001 Koralnik IJ, Du Pasquier RA, Letvin NL. JC virus-specific cytotoxic T lymphocytes in individuals with progressive multifocal leukoencephalopathy Journal of Virology. 75: 3483-3487. PMID 11238876 DOI: 10.1128/JVI.75.7.3483-3487.2001  0.428
2001 Seth A, Markee J, Hoering A, Sevin A, Sabath DE, Schmitz JE, Kuroda MJ, Lifton MA, Hirsch MS, Collier AC, Letvin NL, McElrath MJ. Alterations in T cell phenotype and human immunodeficiency virus type 1-specific cytotoxicity after potent antiretroviral therapy. The Journal of Infectious Diseases. 183: 722-9. PMID 11181148 DOI: 10.1086/318816  0.446
2001 Letvin NL, Bloom BR, Hoffman SL. Prospects for vaccines to protect against AIDS, tuberculosis, and malaria. Jama. 285: 606-11. PMID 11176867 DOI: 10.1001/jama.285.5.606  0.308
2001 Barouch DH, Craiu A, Santra S, Egan MA, Schmitz JE, Kuroda MJ, Fu TM, Nam JH, Wyatt LS, Lifton MA, Krivulka GR, Nickerson CE, Lord CI, Moss B, Lewis MG, ... ... Letvin NL, et al. Elicitation of high-frequency cytotoxic T-lymphocyte responses against both dominant and subdominant simian-human immunodeficiency virus epitopes by DNA vaccination of rhesus monkeys. Journal of Virology. 75: 2462-7. PMID 11160750 DOI: 10.1128/Jvi.75.5.2462-2467.2001  0.455
2000 Barouch DH, Letvin NL. Cytokine-induced augmentation of DNA vaccine-elicited SIV-specific immunity in rhesus monkeys Developments in Biologicals. 104: 85-92. PMID 11713828  0.339
2000 Barouch DH, Letvin NL. DNA vaccination for HIV-1 and SIV Intervirology. 43: 282-287. PMID 11251383 DOI: 10.1159/000053995  0.361
2000 Chen ZW, Shen Y, Davis IC, Shen L, Letvin NL, Fultz PN. Down-regulation of macaque γδ + T cells in lymphoid compartments after rectal infection with SIVsmmPBj14 Journal of Medical Primatology. 29: 143-147. PMID 11085576 DOI: 10.1034/J.1600-0684.2000.290307.X  0.355
2000 Barouch DH, Santra S, Schmitz JE, Kuroda MJ, Fu TM, Wagner W, Bilska M, Craiu A, Zheng XX, Krivulka GR, Beaudry K, Lifton MA, Nickerson CE, Trigona WL, Punt K, ... ... Letvin NL, et al. Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination. Science (New York, N.Y.). 290: 486-92. PMID 11039923 DOI: 10.1126/Science.290.5491.486  0.502
2000 Santra S, Barouch DH, Sharpe AH, Letvin NL. B7 co-stimulatory requirements differ for induction of immune responses by DNA, protein and recombinant pox virus vaccination European Journal of Immunology. 30: 2650-2659. PMID 11009099 DOI: 10.1002/1521-4141(200009)30:9<2650::Aid-Immu2650>3.0.Co;2-K  0.369
2000 Kuroda MJ, Schmitz JE, Lekutis C, Nickerson CE, Lifton MA, Franchini G, Harouse JM, Cheng-Mayer C, Letvin NL. Human immunodeficiency virus type 1 envelope epitope-specific CD4+ T lymphocytes in simian/human immunodeficiency virus-infected and vaccinated rhesus monkeys detected using a peptide-major histocompatibility complex class II tetramer Journal of Virology. 74: 8751-8756. PMID 10954578 DOI: 10.1128/JVI.74.18.8751-8756.2000  0.458
2000 Egan MA, Charini WA, Kuroda MJ, Schmitz JE, Racz P, Tenner-Racz K, Manson K, Wyand M, Lifton MA, Nickerson CE, Fu T, Shiver JW, Letvin NL. Simian immunodeficiency virus (SIV) gag DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses and control viral replication after pathogenic SIV infection. Journal of Virology. 74: 7485-95. PMID 10906202 DOI: 10.1128/JVI.74.16.7485-7495.2000  0.453
2000 Chen ZW, Shen Y, Kou Z, Ibegbu C, Zhou D, Shen L, Morrison P, Bogle C, McClure HM, Nahmias AJ, Sehgal PK, Letvin NL. Prolonged dominance of clonally restricted CD4(+) T cells in macaques infected with simian immunodeficiency viruses. Journal of Virology. 74: 7442-50. PMID 10906197 DOI: 10.1128/JVI.74.16.7442-7450.2000  0.401
2000 Chen ZW, Craiu A, Shen L, Kuroda MJ, Iroku UC, Watkins DI, Voss G, Letvin NL. Simian immunodeficiency virus evades a dominant epitope-specific cytotoxic T lymphocyte response through a mutation resulting in the accelerated dissociation of viral peptide and MHC class I. Journal of Immunology (Baltimore, Md. : 1950). 164: 6474-9. PMID 10843704 DOI: 10.4049/Jimmunol.164.12.6474  0.314
2000 Barouch DH, Craiu A, Kuroda MJ, Schmitz JE, Zheng XX, Santra S, Frost JD, Krivulka GR, Lifton MA, Crabbs CL, Heidecker G, Perry HC, Davies ME, Xie H, Nickerson CE, ... ... Letvin NL, et al. Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys. Proceedings of the National Academy of Sciences of the United States of America. 97: 4192-7. PMID 10759543 DOI: 10.1073/Pnas.050417697  0.366
2000 Seth A, Ourmanov I, Schmitz JE, Kuroda MJ, Lifton MA, Nickerson CE, Wyatt L, Carroll M, Moss B, Venzon D, Letvin NL, Hirsch VM. Immunization with a modified vaccinia virus expressing simian immunodeficiency virus (SIV) Gag-Pol primes for an anamnestic Gag-specific cytotoxic T-lymphocyte response and is associated with reduction of viremia after SIV challenge Journal of Virology. 74: 2502-2509. PMID 10684264 DOI: 10.1128/Jvi.74.6.2502-2509.2000  0.471
2000 Kuroda MJ, Schmitz JE, Seth A, Veazey RS, Nickerson CE, Lifton MA, Dailey PJ, Forman MA, Racz P, Tenner-Racz K, Letvin NL. Simian immunodeficiency virus-specific cytotoxic T lymphocytes and cell-associated viral RNA levels in distinct lymphoid compartments of SIVmac-infected rhesus monkeys Blood. 96: 1474-1479. DOI: 10.1182/blood.v96.4.1474.h8001474_1474_1479  0.374
2000 Kuroda MJ, Schmitz JE, Seth A, Veazey RS, Nickerson CE, Lifton MA, Dailey PJ, Forman MA, Racz P, Tenner-Racz K, Letvin NL. Simian immunodeficiency virus-specific cytotoxic T lymphocytes and cell-associated viral RNA levels in distinct lymphoid compartments of SIVmac-infected rhesus monkeys Blood. 96: 1474-1479. DOI: 10.1182/blood.V96.4.1474  0.374
1999 Letvin NL, Schmitz JE, Jordan HL, Seth A, Hirsch VM, Reimann KA, Kuroda MJ. Cytotoxic T lymphocytes specific for the simian immunodeficiency virus. Immunological Reviews. 170: 127-34. PMID 10566147 DOI: 10.1111/j.1600-065X.1999.tb01334.x  0.492
1999 Zhang Z, Schuler T, Zupancic M, Wietgrefe S, Staskus KA, Reimann KA, Reinhart TA, Rogan M, Cavert W, Miller CJ, Veazey RS, Notermans D, Little S, Danner SA, Richman DD, ... ... Letvin NL, et al. Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells. Science (New York, N.Y.). 286: 1353-7. PMID 10558989 DOI: 10.1126/Science.286.5443.1353  0.364
1999 Koralnik IJ, Schmitz JE, Lifton MA, Forman MA, Letvin NL. Detection of JC virus DNA in peripheral blood cell subpopulations of HIV-1-infected individuals Journal of Neurovirology. 5: 430-435. PMID 10463865  0.306
1999 Santra S, Fultz PN, Letvin NL. Virus-specific cytotoxic T lymphocytes in human immunodeficiency virus type 1-infected chimpanzees Journal of Virology. 73: 7065-7069. PMID 10400811 DOI: 10.1128/Jvi.73.8.7065-7069.1999  0.352
1999 Schmitz JE, Lifton MA, Reimann KA, Montefiori DC, Shen L, Racz P, Tenner-Racz K, Ollert MW, Forman MA, Gelman RS, Vogel CW, Letvin NL. Effect of complement consumption by cobra venom factor on the course of primary infection with simian immunodeficiency virus in rhesus monkeys. Aids Research and Human Retroviruses. 15: 195-202. PMID 10029251 DOI: 10.1089/088922299311619  0.355
1999 Schmitz JE, Kuroda MJ, Santra S, Sasseville VG, Simon MA, Lifton MA, Racz P, Tenner-Racz K, Dalesandro M, Scallon BJ, Ghrayeb J, Forman MA, Montefiori DC, Rieber EP, Letvin NL, et al. Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes. Science (New York, N.Y.). 283: 857-60. PMID 9933172 DOI: 10.1126/Science.283.5403.857  0.428
1999 Egan MA, Kuroda MJ, Voss G, Schmitz JE, Charini WA, Lord CI, Forman MA, Letvin NL. Use of Major Histocompatibility Complex Class I/Peptide/β2M Tetramers To Quantitate CD8+ Cytotoxic T Lymphocytes Specific for Dominant and Nondominant Viral Epitopes in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys Journal of Virology. 73: 5466-5472. DOI: 10.1128/jvi.73.7.5466-5472.1999  0.42
1999 Jordan HL, Kuroda MJ, Schmitz JE, Steenbeke T, Forman MA, Letvin NL. Detection of Simian Immunodeficiency Virus Gag-Specific CD8+ T Lymphocytes in Semen of Chronically Infected Rhesus Monkeys by Cell Staining with a Tetrameric Major Histocompatibility Complex Class I-Peptide Complex Journal of Virology. 73: 4508-4512. DOI: 10.1128/jvi.73.5.4508-4512.1999  0.405
1999 Cayabyab M, Karlsson GB, Etemad-Moghadam BA, Hofmann W, Steenbeke T, Halloran M, Fanton JW, Axthelm MK, Letvin NL, Sodroski JG. Changes in Human Immunodeficiency Virus Type 1 Envelope Glycoproteins Responsible for the Pathogenicity of a Multiply Passaged Simian-Human Immunodeficiency Virus (SHIV-HXBc2) Journal of Virology. 73: 976-984. DOI: 10.1128/jvi.73.2.976-984.1999  0.379
1999 Kuroda MJ, Schmitz JE, Charini WA, Nickerson CE, Lord CI, Forman MA, Letvin NL. Comparative Analysis of Cytotoxic T Lymphocytes in Lymph Nodes and Peripheral Blood of Simian Immunodeficiency Virus-Infected Rhesus Monkeys Journal of Virology. 73: 1573-1579. DOI: 10.1128/jvi.73.2.1573-1579.1999  0.339
1999 Crawford JM, Earl PL, Moss B, Reimann KA, Wyand MS, Manson KH, Bilska M, Zhou JT, Pauza CD, Parren PWHI, Burton DR, Sodroski JG, Letvin NL, Montefiori DC. Characterization of Primary Isolate-Like Variants of Simian-Human Immunodeficiency Virus Journal of Virology. 73: 10199-10207. DOI: 10.1128/jvi.73.12.10199-10207.1999  0.364
1998 Letvin NL, Yasutomi Y, Shen L, Reimann KA, Chen ZW, Schmitz JE, Kuroda MJ. The CD8+ T lymphocyte response during primary SIVmac infection Advances in Experimental Medicine and Biology. 452: 177-179. PMID 9889971 DOI: 10.1007/978-1-4615-5355-7_19  0.387
1998 Karlsson GB, Halloran M, Schenten D, Lee J, Racz P, Tenner-Racz K, Manola J, Gelman R, Etemad-Moghadam B, Desjardins E, Wyatt R, Gerard NP, Marcon L, Margolin D, Fanton J, ... ... Letvin NL, et al. The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques. The Journal of Experimental Medicine. 188: 1159-71. PMID 9743534 DOI: 10.1084/Jem.188.6.1159  0.416
1998 Seth A, Ourmanov I, Kuroda MJ, Schmitz JE, Carroll MW, Wyatt LS, Moss B, Forman MA, Hirsch VM, Letvin NL. Recombinant modified vaccinia virus Ankara-simian immunodeficiency virus gag pol elicits cytotoxic T lymphocytes in rhesus monkeys detected by a major histocompatibility complex class I/peptide tetramer Proceedings of the National Academy of Sciences of the United States of America. 95: 10112-10116. PMID 9707609 DOI: 10.1073/Pnas.95.17.10112  0.494
1998 Letvin NL. Progress in the development of an HIV-1 vaccine Science. 280: 1875-1880. PMID 9632379 DOI: 10.1126/science.280.5371.1875  0.386
1998 Lekutis C, Letvin NL. Substitutions in a major histocompatibility complex class II-restricted human immunodeficiency virus type 1 gp120 epitope can affect CD4+ T-helper- cell function Journal of Virology. 72: 5840-5844. PMID 9621044  0.405
1998 Kuroda MJ, Schmitz JE, Barouch DH, Craiu A, Allen TM, Sette A, Watkins DI, Forman MA, Letvin NL. Analysis of gag-specific cytotoxic T lymphocytes in simian immunodeficiency virus-infected rhesus monkeys by cell staining with a tetrameric major histocompatibility complex class I-peptide complex Journal of Experimental Medicine. 187: 1373-1381. PMID 9565630 DOI: 10.1084/Jem.187.9.1373  0.313
1998 Watanabe N, Sypek JP, Mittler S, Reimann KA, Flores-Villanueva P, Voss G, Lord CI, Letvin NL. Administration of recombinant human interleukin 12 to chronically SIVmac-infected rhesus monkeys. Aids Research and Human Retroviruses. 14: 393-9. PMID 9546798 DOI: 10.1089/aid.1998.14.393  0.326
1998 Cheynier R, Gratton S, Halloran M, Stahmer I, Letvin NL, Wain-Hobson S. Antigenic stimulation by BCG vaccine as an in vivo driving force for SIV replication and dissemination Nature Medicine. 4: 421-427. PMID 9546787 DOI: 10.1038/nm0498-421  0.367
1998 Schmitz JE, Forman MA, Lifton MA, Concepción O, Reimann KA, Crumpacker CS, Daley JF, Gelman RS, Letvin NL. Expression of the CD8αβ-Heterodimer on CD8+ T Lymphocytes in Peripheral Blood Lymphocytes of Human Immunodeficiency Virus− and Human Immunodeficiency Virus+Individuals Blood. 92: 198-206. DOI: 10.1182/blood.V92.1.198.413k13_198_206  0.369
1997 Lekutis C, Letvin NL. HIV-1 Envelope-Specific CD4+ T Helper Cells from Simian/Human Immunodeficiency Virus-Infected Rhesus Monkeys Recognize Epitopes Restricted by MHC Class II DRB1*0406 and DRB*W201 Molecules Journal of Immunology. 159: 2049-2057. PMID 9257873  0.391
1997 Letvin NL, Montefiori DC, Yasutomi Y, Perry HC, Davies ME, Lekutis C, Alroy M, Freed DC, Lord CI, Handt LK, Liu MA, Shiver JW. Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination. Proceedings of the National Academy of Sciences of the United States of America. 94: 9378-83. PMID 9256490 DOI: 10.1073/pnas.94.17.9378  0.314
1997 Shiver JW, Davies ME, Yasutomi Y, Perry HC, Freed DC, Letvin NL, Liu MA. Anti-HIV env immunities elicited by nucleic acid vaccines. Vaccine. 15: 884-7. PMID 9234539 DOI: 10.1016/S0264-410X(96)00251-4  0.419
1997 Reimann KA, Lin W, Bixler S, Browning B, Ehrenfels BN, Lucci J, Miatkowski K, Olson D, Parish TH, Rosa MD, Oleson FB, Hsu YM, Padlan EA, Letvin NL, Burkly LC. A humanized form of a CD4-specific monoclonal antibody exhibits decreased antigenicity and prolonged plasma half-life in rhesus monkeys while retaining its unique biological and antiviral properties. Aids Research and Human Retroviruses. 13: 933-43. PMID 9223409 DOI: 10.1089/aid.1997.13.933  0.334
1997 Lekutis C, Shiver JW, Liu MA, Letvin NL. HIV-1 env DNA vaccine administered to rhesus monkeys elicits MHC class II-restricted CD4+ T helper cells that secrete IFN-gamma and TNF-alpha. Journal of Immunology (Baltimore, Md. : 1950). 158: 4471-7. PMID 9127013  0.459
1997 Karlsson GB, Halloran M, Li J, Park IW, Gomila R, Reimann KA, Axthelm MK, Iliff SA, Letvin NL, Sodroski J. Characterization of molecularly cloned simian-human immunodeficiency viruses causing rapid CD4+ lymphocyte depletion in rhesus monkeys. Journal of Virology. 71: 4218-4225. DOI: 10.1128/Jvi.71.6.4218-4225.1997  0.352
1996 Haigwood NL, Watson A, Sutton WF, McClure J, Lewis A, Ranchalis J, Travis B, Voss G, Letvin NL, Hu SL, Hirsch VM, Johnson PR. Passive immune globulin therapy in the SIV/macaque model: early intervention can alter disease profile. Immunology Letters. 51: 107-14. PMID 8811353 DOI: 10.1016/0165-2478(96)02563-1  0.301
1996 Voss G, Letvin NL. Definition of human immunodeficiency virus type 1 gp120 and gp41 cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I alleles in simian-human immunodeficiency virus-infected rhesus monkeys Journal of Virology. 70: 7335-7340. PMID 8794394  0.377
1996 Reimann KA, John TLI, Voss G, Lekutis C, Tenner-Racz K, Racz P, Lin W, Montefiori DC, Lee-Parritz DE, Yichen LU, Collman RG, Sodroski J, Letvin NL. An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys Journal of Virology. 70: 3198-3206. PMID 8627800 DOI: 10.1128/Jvi.70.5.3198-3206.1996  0.376
1996 Chen ZW, Shen L, Regan JD, Kou Z, Ghim SH, Letvin NL. The T cell receptor gene usage by simian immunodeficiency virus Gag-specific cytotoxic T lymphocytes in rhesus monkeys Journal of Immunology. 156: 1469-1475. PMID 8568249  0.354
1996 Reimann KA, Li JT, Veazey R, Halloran M, Park IW, Karlsson GB, Sodroski J, Letvin NL. A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys. Journal of Virology. 70: 6922-6928. DOI: 10.1128/Jvi.70.10.6922-6928.1996  0.303
1996 Yasutomi Y, Robinson HL, Lu S, Mustafa F, Lekutis C, Arthos J, Mullins JI, Voss G, Manson K, Wyand M, Letvin NL. Simian immunodeficiency virus-specific cytotoxic T-lymphocyte induction through DNA vaccination of rhesus monkeys. Journal of Virology. 70: 678-681. DOI: 10.1128/Jvi.70.1.678-681.1996  0.473
1995 Reimann KA, Waite BC, Lee-Parritz DE, Lin W, Uchanska-Ziegler B, O'Connell MJ, Letvin NL. Use of human leukocyte-specific monoclonal antibodies for clinically immunophenotyping lymphocytes of rhesus monkeys. Cytometry. 17: 102-8. PMID 8001455 DOI: 10.1002/cyto.990170113  0.312
1995 Letvin NL, Li J, Halloran M, Cranage MP, Rud EW, Sodroski J. Prior infection with a nonpathogenic chimeric simian-human immunodeficiency virus does not efficiently protect macaques against challenge with simian immunodeficiency virus Journal of Virology. 69: 4569-4571. PMID 7769725 DOI: 10.1128/Jvi.69.7.4569-4571.1995  0.347
1995 Voss G, Li J, Manson K, Wyand M, Sodroski J, Letvin NL. Human immunodeficiency virus type 1 envelope glycoprotein-specific cytotoxic T lymphocytes in simian-human immunodeficiency virus-infected rhesus monkeys Virology. 208: 770-775. PMID 7747449 DOI: 10.1006/Viro.1995.1209  0.4
1995 Bachelder RE, Bilancieri J, Lin W, Letvin NL. A human recombinant fab identifies a human immunodeficiency virus type 1-induced conformational change in cell surface-expressed CD4 Journal of Virology. 69: 5734-5742. PMID 7637018  0.369
1995 Reimann KA, Cate RL, Wu Y, Palmer L, Olson D, Waite BC, Letvin NL, Burkly LC. In vivo administration of CD4-specific monoclonal antibody: effect on provirus load in rhesus monkeys chronically infected with the simian immunodeficiency virus of macaques. Aids Research and Human Retroviruses. 11: 517-25. PMID 7632466 DOI: 10.1089/aid.1995.11.517  0.342
1995 Yasutomi Y, McAdam SN, Boyson JE, Piekarczyk MS, Watkins DI, Letvin NL. A MHC class I B locus allele-restricted simian immunodeficiency virus envelope CTL epitope in rhesus monkeys Journal of Immunology. 154: 2516-2522. PMID 7532670  0.378
1995 Montefiori DC, Reimann KA, Letvin NL, Zhou J, Hu SL. Studies of complement-activating antibodies in the SIV/macaque model of acute primary infection and vaccine protection Aids Research and Human Retroviruses. 11: 963-970. PMID 7492443  0.31
1994 Shen L, Chen ZW, Letvin NL. The repertoire of cytotoxic T lymphocytes in the recognition of mutant simian immunodeficiency virus variants Journal of Immunology. 153: 5849-5854. PMID 7989780  0.305
1994 Morimoto C, Lord CI, Zhang C, Duke-Cohan JS, Letvin NL, Schlossman SF. Role of CD26/dipeptidyl peptidase IV in human immunodeficiency virus type 1 infection and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 91: 9960-4. PMID 7937926 DOI: 10.1073/pnas.91.21.9960  0.301
1994 Chen ZW, Kou ZC, Shen L, Regan JD, Lord CI, Halloran M, Lee-Parritz D, Fultz PN, Letvin NL. An acutely lethal simian immunodeficiency virus stimulates expansion of Vβ7- And Vβ14-expressing T lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 91: 7501-7505. PMID 7914369 DOI: 10.1073/pnas.91.16.7501  0.392
1994 Watanabe N, McAdam SN, Boyson JE, Piekarczyk MS, Yasutomi Y, Watkins DI, Letvin NL. A simian immunodeficiency virus envelope V3 cytotoxic T-lymphocyte epitope in rhesus monkeys and its restricting major histocompatibility complex class I molecule mamu-A*02 Journal of Virology. 68: 6690-6696. PMID 7521921 DOI: 10.1128/Jvi.68.10.6690-6696.1994  0.374
1993 Reimann KA, Burkly LC, Burrus B, Waite BC, Lord CI, Letvin NL. In vivo administration to rhesus monkeys of a CD4-specific monoclonal antibody capable of blocking AIDS virus replication. Aids Research and Human Retroviruses. 9: 199-207. PMID 8471310 DOI: 10.1089/aid.1993.9.199  0.331
1993 Yasutomi Y, Reimann KA, Lord CI, Miller MD, Letvin NL. Simian immunodeficiency virus-specific CD8+ lymphocyte response in acutely infected rhesus monkeys Journal of Virology. 67: 1707-1711. PMID 8437240  0.361
1993 Letvin NL, Miller MD, Shen L, Chen ZW, Yasutomi Y. Simian immunodeficiency virus-specific cytotoxic T lymphocytes in rhesus monkeys: Characterization and vaccine induction Seminars in Immunology. 5: 215-223. PMID 8394161  0.463
1993 Chen ZW, Kou ZC, Shen L, Reimann KA, Letvin NL. Conserved T-cell receptor repertoire in simian immunodeficiency virus-infected rhesus monkeys Journal of Immunology. 151: 2177-2187. PMID 8393899  0.351
1993 Shen L, Mazzara GP, DiSciullo SO, Panicali DL, Letvin NL. Immunization with lentivirus-like particles elicits a potent SIV-specific recall cytotoxic T-lymphocyte response in rhesus monkeys Aids Research and Human Retroviruses. 9: 129-132. PMID 8384466 DOI: 10.1089/aid.1993.9.129  0.425
1993 Yasutomi Y, Palker TJ, Gardner MB, Haynes BF, Letvin NL. Synthetic peptide in mineral oil adjuvant elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes in rhesus monkeys Journal of Immunology. 151: 5096-5105. PMID 7691965  0.406
1993 Lairmore MD, Hofheinz DE, Letvin NL, Stoner CS, Pearlman S, Toedter GP. Detection of simian immunodeficiency virus and human immunodeficiency virus type 2 capsid antigens by a monoclonal antibody-based antigen capture assay. Aids Research and Human Retroviruses. 9: 565-71. PMID 7688521 DOI: 10.1089/Aid.1993.9.565  0.33
1992 Yamamoto H, Ringler DJ, Miller MD, Yasutomi Y, Hasunuma T, Letvin NL. Simian immunodeficiency virus-specific cytotoxic T lymphocytes are present in the aids-associated skin rash in rhesus monkeys Journal of Immunology. 149: 728-734. PMID 1624810  0.34
1992 Watanabe M, Boyson JE, Lord CI, Letvin NL. Chimpanzees immunized with recombinant soluble CD4 develop anti-self CD4 antibody responses with anti-human immunodeficiency virus activity Proceedings of the National Academy of Sciences of the United States of America. 89: 5103-5107. PMID 1594618  0.337
1992 Panicali DL, Mazzara G, Sullivan JL, Hesselton R, Shen L, Letvin N, Daniel M, Desrosiers R, Stott EJ. Use of lentivirus-like particles alone and in combination with live vaccinia-virus-based vaccines Aids Research and Human Retroviruses. 8: 1449. PMID 1466979 DOI: 10.1089/Aid.1992.8.1449  0.391
1992 Miller MD, Gould-Fogerite S, Shen L, Woods RM, Koenig S, Mannino RJ, Letvin NL. Vaccination of rhesus monkeys with synthetic peptide in a fusogenic proteoliposome elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes. The Journal of Experimental Medicine. 176: 1739-44. PMID 1460429 DOI: 10.1084/jem.176.6.1739  0.467
1992 Massacesi L, Joshi N, Lee-Parritz D, Rombos A, Letvin NL, Hauser SL. Experimental allergic encephalomyelitis in cynomolgus monkeys. Quantitation of T cell responses in peripheral blood. The Journal of Clinical Investigation. 90: 399-404. PMID 1379611 DOI: 10.1172/Jci115874  0.305
1992 Letvin NL. Animal models for the study of human immunodeficiency virus infections Current Opinion in Immunology. 4: 481-485. PMID 1356349 DOI: 10.1016/S0952-7915(06)80043-9  0.339
1992 Chen ZW, Yamamoto H, Watkins DI, Levinson G, Letvin NL. Predominant use of a T-cell receptor Vβ gene family in simian immunodeficiency virus gag-specific cytotoxic T lymphocytes in a rhesus monkey Journal of Virology. 66: 3913-3917. PMID 1316491 DOI: 10.1128/Jvi.66.6.3913-3917.1992  0.357
1991 Watanabe M, Levine CG, Shen L, Fisher RA, Letvin NL. Immunization of simian immunodeficiency virus-infected rhesus monkeys with soluble human CD4 elicits an antiviral response Proceedings of the National Academy of Sciences of the United States of America. 88: 4616-4620. PMID 2052546  0.371
1991 Watanabe M, Chen ZW, Tsubota H, Lord CI, Levine CG, Letvin NL. Soluble human CD4 elicits an antibody response in rhesus monkeys that inhibits simian immunodeficiency virus replication Proceedings of the National Academy of Sciences of the United States of America. 88: 120-124. PMID 1986356  0.318
1991 Reimann KA, Snyder GB, Chalifoux LV, Waite BC, Miller MD, Yamamoto H, Spertini O, Letvin NL. An activated CD8+ lymphocyte appears in lymph nodes of rhesus monkeys early after infection with simian immunodeficiency virus. The Journal of Clinical Investigation. 88: 1113-20. PMID 1717508 DOI: 10.1172/JCI115410  0.354
1991 Miller MD, Yamamoto H, Hughes AL, Watkins DI, Letvin NL. Definition of an epitope and MHC class I molecule recognized by Gag-specific cytotoxic T lymphocytes in SIVmac-infected rhesus monkeys Journal of Immunology. 147: 320-329. PMID 1711081  0.387
1991 Shen L, Chen ZW, Miller MD, Stallard V, Mazzara GP, Panicali DL, Letvin NL. Recombinant virus vaccine-induced SIV-specific CD8+ cytotoxic T lymphocytes Science. 252: 440-443. PMID 1708168 DOI: 10.1126/science.1708168  0.51
1991 Watanabe M, Ringler DJ, Fultz PN, Mackey JJ, Boyson JE, Levine CG, Letvin NL. A Chimpanzee-Passaged Human Immunodeficiency Virus Isolate Is Cytopathic for Chimpanzee Cells but Does Not Induce Disease Journal of Virology. 65: 3344-3348. PMID 1674550  0.306
1990 Tsubota H, Winkler G, Meade HM, Jakubowski A, Thomas DW, Letvin NL. CD4-Pseudomonas exotoxin conjugates delay but do not fully inhibit human immunodeficiency virus replication in lymphocytes in vitro Journal of Clinical Investigation. 86: 1684-1689. PMID 2243139  0.335
1990 Miller MD, Lord CI, Stallard V, Mazzara GP, Letvin NL. The gag-specific cytotoxic T lymphocytes in rhesus monkeys infected wit the simian immunodeficiency virus of macaques Journal of Immunology. 144: 122-128. PMID 2153161  0.453
1989 Tsubota H, Lord CI, Watkins DI, Morimoto C, Letvin NL. A cytotoxic T lymphocyte inhibits acquired immunodeficiency syndrome virus replication in peripheral blood lymphocytes Journal of Experimental Medicine. 169: 1421-1434. PMID 2784486 DOI: 10.1084/Jem.169.4.1421  0.422
1989 Desrosiers RC, Wyand MS, Kodama T, Ringler DJ, Arthur LO, Sehgal PK, Letvin NL, King NW, Daniel MD. Vaccine protection against simian immunodeficiency virus infection. Proceedings of the National Academy of Sciences of the United States of America. 86: 6353-7. PMID 2548210 DOI: 10.1073/Pnas.86.16.6353  0.375
1989 Watanabe M, Reimann KA, DeLong PA, Liu T, Fisher RA, Letvin NL. Effect of recombinant soluble CD4 in rhesus monkeys infected with simian immunodeficiency virus of macaques Nature. 337: 267-270. PMID 2536140  0.35
1988 Watkins DI, Kannagi M, Stone ME, Letvin NL. Major histocompatibility complex class I molecules of nonhuman primates European Journal of Immunology. 18: 1425-1432. PMID 3169121 DOI: 10.1002/Eji.1830180919  0.301
1988 Kannagi M, Chalifoux LV, Lord CI, Letvin NL. Suppression of simian immunodeficiency virus replication in vitro by CD8+ lymphocytes Journal of Immunology. 140: 2237-2242. PMID 2965185  0.392
1987 Daniel MD, Desrosiers RC, Letvin NL, King NW, Schmidt DK, Sehgal P, Hunt RD. Simian models for AIDS Cancer Detection and Prevention. Supplement : Official Publication of the International Society For Preventive Oncology, Inc. 1: 501-507. PMID 3480063  0.357
1987 Chalifoux LV, Ringler DJ, King NW, Sehgal PK, Desrosiers RC, Daniel MD, Letvin NL. Lymphadenopathy in macaques experimentally infected with the simian immunodeficiency virus (SIV) American Journal of Pathology. 128: 104-110. PMID 3037910  0.388
1987 Kannagi M, Kiyotaki M, King NW, Lord CI, Letvin NL. Simian immunodeficiency virus induces expression of class II major histocompatibility complex structures on infected target cells in vitro Journal of Virology. 61: 1421-1426. PMID 3033270  0.311
1987 Ringler DJ, Hancock WW, King NW, Letvin NL, Daniel MD, Desrosiers RC, Murphy GF. Immunophenotypic characterization of the cutaneous exanthem of SIV-infected rhesus monkeys. Apposition of degenerative Langerhans cells and cytotoxic lymphocytes during the development of acquired immunodeficiency syndrome American Journal of Pathology. 126: 199-207. PMID 3030113  0.324
1987 Morimoto C, Rudd CE, Letvin NL, Schlossman SF. A novel epitope of the LFA-1 antigen which can distinguish killer effector and suppressor cells in human CD8 cells Nature. 330: 479-482. PMID 2446140  0.334
1987 Dillner J, Rabin H, Letvin N, Henle W, Henle G, Klein G. Nuclear DNA-binding proteins determined by the Epstein-Barr virus-related simian lymphotropic herpesviruses H. gorilla, H. pan, H. pongo and H. papio. The Journal of General Virology. 68: 1587-96. PMID 2438377 DOI: 10.1099/0022-1317-68-6-1587  0.321
1986 Kannagi M, Kiyotaki M, Desrosiers RC, Reimann KA, King NW, Waldron LM, Letvin NL. Humoral immune responses to T cell tropic retrovirus simian T lymphotropic virus type III in monkeys with experimentally induced acquired immune deficiency-like syndrome Journal of Clinical Investigation. 78: 1229-1236. PMID 3771794 DOI: 10.1172/Jci112706  0.39
1986 Kiyotaki M, Desrosiers RC, Letvin NL. Herpesvirus saimiri strain 11 immortalizes a restricted marmoset T8 lymphocyte subpopulation in vitro Journal of Experimental Medicine. 164: 926-931. PMID 3018122 DOI: 10.1084/Jem.164.3.926  0.307
1985 Kanki PJ, McLane MF, King NW, Letvin NL, Hunt RD, Sehgal P, Daniel MD, Desrosiers RC, Essex M. Serologic identification and characterization of a macaque T-lymphotropic retrovirus closely related to HTLV-III. Science (New York, N.Y.). 228: 1199-201. PMID 3873705 DOI: 10.1126/Science.3873705  0.406
1985 Daniel MD, Letvin NL, King NW, Kannagi M, Sehgal PK, Hunt RD, Kanki PJ, Essex M, Desrosiers RC. Isolation of T-cell tropic HTLV-III-like retrovirus from macaques. Science (New York, N.Y.). 228: 1201-4. PMID 3159089 DOI: 10.1126/Science.3159089  0.505
1985 Morimoto C, Letvin NL, Distaso JA, Aldrich WR, Schlossman SF. The isolation and characterization of the human suppressor inducer T cell subset Journal of Immunology. 134: 1508-1515. PMID 3155770  0.306
1985 Kannagi M, Yetz JM, Letvin NL. in vitro growth characteristics of simian T-lymphotropic virus type III Proceedings of the National Academy of Sciences of the United States of America. 82: 7053-7057. PMID 2996002  0.38
1985 Letvin NL, Daniel MD, Sehgal PK, Desrosiers RC, Hunt RD, Waldron LM, MacKey JJ, Schmidt DK, Chalifoux LV, King NW. Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III. Science (New York, N.Y.). 230: 71-3. PMID 2412295 DOI: 10.1126/Science.2412295  0.326
1985 Letvin N, Ritz J, Guida L, Yetz J, Lambert J, Reinherz E, Schlossman S. In vivo administration of lymphocyte-specific monoclonal antibodies in nonhuman primates: I. Effects of anti-T11 antibodies on the circulating T cell pool Blood. 66: 961-966. DOI: 10.1182/Blood.V66.4.961.Bloodjournal664961  0.387
1984 Daniel MD, King NW, Letvin NL, Hunt RD, Sehgal PK, Desrosiers RC. A new type D retrovirus isolated from macaques with an immunodeficiency syndrome. Science (New York, N.Y.). 223: 602-5. PMID 6695172 DOI: 10.1126/Science.6695172  0.339
1984 Homma T, Kanki PJ, King NW, Hunt RD, O'Connell MJ, Letvin NL, Daniel MD, Desrosiers RC, Yang CS, Essex M. Lymphoma in macaques: association with virus of human T lymphotrophic family. Science (New York, N.Y.). 225: 716-8. PMID 6087453 DOI: 10.1126/Science.6087453  0.355
1983 Letvin NL, Todd RF, Palley LS, Schlossman SF, Griffin JD. Conservation of myeloid surface antigens on primate granulocytes Blood. 61: 408-410. PMID 6821706 DOI: 10.1182/Blood.V61.2.408.Bloodjournal612408  0.31
1982 Letvin NL, Huber BT, Benacerraf B. B-lymphocyte responses to trinitrophenyl-ficoll. II. Decreased splenic adherent cell function in mice expressing the xid gene. Cellular Immunology. 70: 241-7. PMID 6982103 DOI: 10.1016/0008-8749(82)90325-2  0.396
1982 Letvin NL, Rock KL, Nepom JT, Gramm CF, Benacerraf B. Antibody responses to trinitrophenyl (TNP)-L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) in microcultures: anti-hapten and anti-carrier responses appear to be under separable control. Cellular Immunology. 71: 89-98. PMID 6814767 DOI: 10.1016/0008-8749(82)90498-1  0.372
1981 Letvin NL, Benacerraf B, Germain RN. B-lymphocyte responses to trinitrophenyl-conjugated Ficoll: requirement for T lymphocytes and Ia-bearing adherent cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 5113-7. PMID 6975477 DOI: 10.1073/Pnas.78.8.5113  0.624
1981 Letvin NL, Benacerraf B, Germain RN. Plaque-forming cell responses to trinitrophenyl (TNP)-L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) in microcultures are not under conventional Ir gene control. Journal of Immunology (Baltimore, Md. : 1950). 127: 1534-8. PMID 6792278  0.414
1981 Letvin NL, Kauffman RS, Finberg R. T lymphocyte immunity to reovirus: Cellular requirements for generation and role in clearance of primary infections Journal of Immunology. 127: 2334-2339. PMID 6271871  0.36
1981 Picus J, Germain RN, Fox IJ, Greene MI, Benacerraf B, Letvin NL. Immunologic effects of whole-body ultraviolet (uv) irradiation. III Defective splenic adherent cell function in alloantigen-stimulated T-cell proliferation. Cellular Immunology. 63: 300-7. PMID 6168395 DOI: 10.1016/0008-8749(81)90009-5  0.563
1980 Letvin NL, Fox IJ, Greene MI, Benacerraf B, Germain RN. Immunologic effects of whole body ultraviolet (UV) irradiation. II. Defect in splenic adherent cell antigen presentation for stimulation of T cell proliferation. Journal of Immunology (Baltimore, Md. : 1950). 125: 1402-4. PMID 6967900  0.431
1980 Letvin NL, Greene MI, Benacerraf B, Germain RN. Immunologic effects of whole-body ultraviolet irradiation: selective defect in splenic adherent cell function in vitro. Proceedings of the National Academy of Sciences of the United States of America. 77: 2881-5. PMID 6967214 DOI: 10.1073/Pnas.77.5.2881  0.569
1980 Letvin NL, Nepom JT, Greene MI, Benacerraf B, Germain RN. Loss of Ia-bearing splenic adherent cells after whole body ultraviolet irradiation. Journal of Immunology (Baltimore, Md. : 1950). 125: 2550-4. PMID 6933201  0.321
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