Allan J. Zajac - Publications

Affiliations: 
University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Immunology, Microbiology Biology

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Almanan M, Raynor J, Ogunsulire I, Malyshkina A, Mukherjee S, Hummel SA, Ingram JT, Saini A, Xie MM, Alenghat T, Way SS, Deepe GS, Divanovic S, Singh H, Miraldi E, ... Zajac AJ, et al. IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression. Science Advances. 6: eabb0806. PMID 32832688 DOI: 10.1126/sciadv.abb0806  0.48
2019 Poholek CH, Dulson SJ, Zajac AJ, Harrington LE. IL-21 Controls ILC3 Cytokine Production and Promotes a Protective Phenotype in a Mouse Model of Colitis. Immunohorizons. 3: 194-202. PMID 31356165 DOI: 10.4049/immunohorizons.1900005  0.4
2019 Kahan SM, Zajac AJ. Immune Exhaustion: Past Lessons and New Insights from Lymphocytic Choriomeningitis Virus. Viruses. 11. PMID 30781904 DOI: 10.3390/v11020156  0.6
2018 Dulson SJ, Harrington LE, Zajac AJ. Inscribing the core memories of killers. Cellular & Molecular Immunology. PMID 30405147 DOI: 10.1038/s41423-018-0178-9  0.4
2017 Kahan SM, Zajac AJ. Late arising T follicular helper cells cultivate the B cell crop during chronic infections. Science Immunology. 2. PMID 29196451 DOI: 10.1126/sciimmunol.aap9339  0.6
2016 Tian Y, Mollo SB, Harrington LE, Zajac AJ. IL-10 Regulates Memory T Cell Development and the Balance between Th1 and Follicular Th Cell Responses during an Acute Viral Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 27402701 DOI: 10.4049/jimmunol.1502481  0.4
2016 Tian Y, Zajac AJ. IL-21 and T Cell Differentiation: Consider the Context. Trends in Immunology. PMID 27389961 DOI: 10.1016/j.it.2016.06.001  0.88
2016 Selin LK, Zajac AJ. Editorial overview: Viral immunology. Current Opinion in Virology. PMID 26979471 DOI: 10.1016/j.coviro.2016.01.012  0.88
2016 Tian Y, Cox MA, Kahan SM, Ingram JT, Bakshi RK, Zajac AJ. A Context-Dependent Role for IL-21 in Modulating the Differentiation, Distribution, and Abundance of Effector and Memory CD8 T Cell Subsets. Journal of Immunology (Baltimore, Md. : 1950). PMID 26826252 DOI: 10.4049/jimmunol.1401236  0.88
2015 Kahan SM, Wherry EJ, Zajac AJ. T cell exhaustion during persistent viral infections. Virology. 479: 180-93. PMID 25620767 DOI: 10.1016/j.virol.2014.12.033  0.88
2014 Overton ET, Sterrett S, Westfall AO, Kahan SM, Burkholder G, Zajac AJ, Goepfert PA, Bansal A. Effects of atorvastatin and pravastatin on immune activation and T-cell function in antiretroviral therapy-suppressed HIV-1-infected patients. Aids (London, England). 28: 2627-31. PMID 25574964 DOI: 10.1097/QAD.0000000000000475  0.88
2014 Kahan SM, Zajac AJ. A stay of execution: type I interferons pardon T cells from death by natural killers. Immunity. 40: 861-2. PMID 24950208 DOI: 10.1016/j.immuni.2014.05.009  0.88
2014 Ding Y, Li J, Yang P, Luo B, Wu Q, Zajac AJ, Wildner O, Hsu HC, Mountz JD. Interleukin-21 promotes germinal center reaction by skewing the follicular regulatory T cell to follicular helper T cell balance in autoimmune BXD2 mice. Arthritis & Rheumatology (Hoboken, N.J.). 66: 2601-12. PMID 24909430 DOI: 10.1002/art.38735  0.88
2014 Zajac AJ, Harrington LE. Tissue-resident T cells lose their S1P1 exit visas. Cellular & Molecular Immunology. 11: 221-3. PMID 24561454 DOI: 10.1038/cmi.2014.7  0.88
2014 Zajac AJ, Harrington LE. Immune Response to Viruses: Cell-Mediated Immunity Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.02604-0  0.4
2013 Mollo SB, Ingram JT, Kress RL, Zajac AJ, Harrington LE. Virus-specific CD4 and CD8 T cell responses in the absence of Th1-associated transcription factors. Journal of Leukocyte Biology. PMID 24231259 DOI: 10.1189/jlb.0813429  0.88
2013 Mollo SB, Zajac AJ, Harrington LE. Temporal requirements for B cells in the establishment of CD4 T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 191: 6052-9. PMID 24218454 DOI: 10.4049/jimmunol.1302033  0.88
2013 Phares TW, DiSano KD, Hinton DR, Hwang M, Zajac AJ, Stohlman SA, Bergmann CC. IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis. Journal of Neuroimmunology. 263: 43-54. PMID 23992866 DOI: 10.1016/j.jneuroim.2013.07.019  0.88
2013 Ding Y, Li J, Wu Q, Yang P, Luo B, Xie S, Druey KM, Zajac AJ, Hsu HC, Mountz JD. IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 1614-24. PMID 23858031 DOI: 10.4049/jimmunol.1300479  0.88
2013 Cox MA, Barnum SR, Bullard DC, Zajac AJ. ICAM-1-dependent tuning of memory CD8 T-cell responses following acute infection. Proceedings of the National Academy of Sciences of the United States of America. 110: 1416-21. PMID 23297203 DOI: 10.1073/pnas.1213480110  0.88
2013 Cox MA, Kahan SM, Zajac AJ. Anti-viral CD8 T cells and the cytokines that they love. Virology. 435: 157-69. PMID 23217625 DOI: 10.1016/j.virol.2012.09.012  0.88
2011 Petrelli A, Carvello M, Vergani A, Lee KM, Tezza S, Du M, Kleffel S, Chengwen L, Mfarrej BG, Hwu P, Secchi A, Leonard WJ, Young D, Sayegh MH, Markmann JF, ... Zajac AJ, et al. IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response. Diabetes. 60: 3223-34. PMID 22013017 DOI: 10.2337/db11-0880  0.88
2011 Ingram JT, Yi JS, Zajac AJ. Exhausted CD8 T cells downregulate the IL-18 receptor and become unresponsive to inflammatory cytokines and bacterial co-infections. Plos Pathogens. 7: e1002273. PMID 21980291 DOI: 10.1371/journal.ppat.1002273  0.88
2011 Cox MA, Harrington LE, Zajac AJ. Cytokines and the inception of CD8 T cell responses. Trends in Immunology. 32: 180-6. PMID 21371940 DOI: 10.1016/j.it.2011.01.004  0.88
2011 Williams LD, Bansal A, Sabbaj S, Heath SL, Song W, Tang J, Zajac AJ, Goepfert PA. Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers. Journal of Virology. 85: 2316-24. PMID 21159862 DOI: 10.1128/JVI.01476-10  0.88
2010 Yi JS, Ingram JT, Zajac AJ. IL-21 deficiency influences CD8 T cell quality and recall responses following an acute viral infection. Journal of Immunology (Baltimore, Md. : 1950). 185: 4835-45. PMID 20844201 DOI: 10.4049/jimmunol.1001032  0.88
2010 Yi JS, Cox MA, Zajac AJ. Interleukin-21: a multifunctional regulator of immunity to infections. Microbes and Infection / Institut Pasteur. 12: 1111-9. PMID 20817119 DOI: 10.1016/j.micinf.2010.08.008  0.88
2010 Mackerness KJ, Cox MA, Lilly LM, Weaver CT, Harrington LE, Zajac AJ. Pronounced virus-dependent activation drives exhaustion but sustains IFN-γ transcript levels. Journal of Immunology (Baltimore, Md. : 1950). 185: 3643-51. PMID 20720198 DOI: 10.4049/jimmunol.1000841  0.88
2010 Cox MA, Zajac AJ. Shaping successful and unsuccessful CD8 T cell responses following infection. Journal of Biomedicine & Biotechnology. 2010: 159152. PMID 20379363 DOI: 10.1155/2010/159152  0.88
2010 Yi JS, Cox MA, Zajac AJ. T-cell exhaustion: characteristics, causes and conversion. Immunology. 129: 474-81. PMID 20201977 DOI: 10.1111/j.1365-2567.2010.03255.x  0.88
2009 Yi JS, Du M, Zajac AJ. A vital role for interleukin-21 in the control of a chronic viral infection. Science (New York, N.Y.). 324: 1572-6. PMID 19443735 DOI: 10.1126/science.1175194  0.88
2008 Harrington LE, Janowski KM, Oliver JR, Zajac AJ, Weaver CT. Memory CD4 T cells emerge from effector T-cell progenitors. Nature. 452: 356-60. PMID 18322463 DOI: 10.1038/nature06672  0.88
2007 Parker SD, Rottinghaus ST, Zajac AJ, Yue L, Hunter E, Whitley RJ, Parker JN. HIV-1(89.6) Gag expressed from a replication competent HSV-1 vector elicits persistent cellular immune responses in mice. Vaccine. 25: 6764-73. PMID 17706843 DOI: 10.1016/j.vaccine.2007.06.064  0.88
2007 Sabbaj S, Heath SL, Bansal A, Vohra S, Kilby JM, Zajac AJ, Goepfert PA. Functionally competent antigen-specific CD127(hi) memory CD8+ T cells are preserved only in HIV-infected individuals receiving early treatment. The Journal of Infectious Diseases. 195: 108-17. PMID 17152014 DOI: 10.1086/509510  0.88
2006 Chen J, Hsu HC, Zajac AJ, Wu Q, Yang P, Xu X, McPherson SA, Li J, Curiel DT, Mountz JD. In vivo analysis of adenovirus-specific cytotoxic T lymphocyte response in mice deficient in CD28, fas ligand, and perforin. Human Gene Therapy. 17: 669-82. PMID 16776575 DOI: 10.1089/hum.2006.17.669  0.88
2006 Wojciechowski S, Jordan MB, Zhu Y, White J, Zajac AJ, Hildeman DA. Bim mediates apoptosis of CD127(lo) effector T cells and limits T cell memory. European Journal of Immunology. 36: 1694-706. PMID 16761315 DOI: 10.1002/eji.200635897  0.88
2006 Gaddis DE, Fuller MJ, Zajac AJ. CD8 T-cell Immunodominance, Repertoire, and Memory Immunodominance: the Choice of the Immune System. 109-145. DOI: 10.1002/3527608028.ch6  0.88
2006 Zajac AJ. CD127 and virus infection Modern Aspects of Immunobiology. 19: 2.  0.88
2005 Tebo AE, Fuller MJ, Gaddis DE, Kojima K, Rehani K, Zajac AJ. Rapid recruitment of virus-specific CD8 T cells restructures immunodominance during protective secondary responses. Journal of Virology. 79: 12703-13. PMID 16188973 DOI: 10.1128/JVI.79.20.12703-12713.2005  0.88
2005 Fuller MJ, Hildeman DA, Sabbaj S, Gaddis DE, Tebo AE, Shang L, Goepfert PA, Zajac AJ. Cutting edge: emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help. Journal of Immunology (Baltimore, Md. : 1950). 174: 5926-30. PMID 15879083  0.88
2005 Chen J, Zajac AJ, McPherson SA, Hsu HC, Yang P, Wu Q, Xu X, Wang X, Fujihashi K, Curiel DT, Mountz JD. Primary adenovirus-specific cytotoxic T lymphocyte response occurs after viral clearance and liver enzyme elevation. Gene Therapy. 12: 1079-88. PMID 15815704 DOI: 10.1038/sj.gt.3302494  0.88
2004 Fuller MJ, Khanolkar A, Tebo AE, Zajac AJ. Maintenance, loss, and resurgence of T cell responses during acute, protracted, and chronic viral infections. Journal of Immunology (Baltimore, Md. : 1950). 172: 4204-14. PMID 15034033  0.88
2004 Khanolkar A, Fuller MJ, Zajac AJ. CD4 T cell-dependent CD8 T cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 172: 2834-44. PMID 14978084  0.88
2003 Gao F, Li Y, Decker JM, Peyerl FW, Bibollet-Ruche F, Rodenburg CM, Chen Y, Shaw DR, Allen S, Musonda R, Shaw GM, Zajac AJ, Letvin N, Hahn BH. Codon usage optimization of HIV type 1 subtype C gag, pol, env, and nef genes: in vitro expression and immune responses in DNA-vaccinated mice. Aids Research and Human Retroviruses. 19: 817-23. PMID 14585212 DOI: 10.1089/088922203769232610  0.88
2003 Zajac AJ, Dye JM, Quinn DG. Control of lymphocytic choriomeningitis virus infection in granzyme B deficient mice. Virology. 305: 1-9. PMID 12504535 DOI: 10.1006/viro.2002.1754  0.88
2003 Fuller MJ, Zajac AJ. Ablation of CD8 and CD4 T cell responses by high viral loads. Journal of Immunology (Baltimore, Md. : 1950). 170: 477-86. PMID 12496434  0.88
2002 Khanolkar A, Fuller MJ, Zajac AJ. T cell responses to viral infections: lessons from lymphocytic choriomeningitis virus. Immunologic Research. 26: 309-21. PMID 12403369 DOI: 10.1385/IR:26:1-3:309  0.88
2002 Davis IC, Zajac AJ, Nolte KB, Botten J, Hjelle B, Matalon S. Elevated generation of reactive oxygen/nitrogen species in hantavirus cardiopulmonary syndrome. Journal of Virology. 76: 8347-59. PMID 12134039 DOI: 10.1128/JVI.76.16.8347-8359.2002  0.88
2002 McMahon CW, Zajac AJ, Jamieson AM, Corral L, Hammer GE, Ahmed R, Raulet DH. Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells. Journal of Immunology (Baltimore, Md. : 1950). 169: 1444-52. PMID 12133970  0.88
2001 Puglielli MT, Zajac AJ, van der Most RG, Dzuris JL, Sette A, Altman JD, Ahmed R. In vivo selection of a lymphocytic choriomeningitis virus variant that affects recognition of the GP33-43 epitope by H-2Db but not H-2Kb. Journal of Virology. 75: 5099-107. PMID 11333891 DOI: 10.1128/JVI.75.11.5099-5107.2001  0.88
2000 Grayson JM, Zajac AJ, Altman JD, Ahmed R. Cutting edge: increased expression of Bcl-2 in antigen-specific memory CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 164: 3950-4. PMID 10754284 DOI: 10.4049/jimmunol.164.8.3950  0.88
1999 Zajac AJ, Vance RE, Held W, Sourdive DJ, Altman JD, Raulet DH, Ahmed R. Impaired anti-viral T cell responses due to expression of the Ly49A inhibitory receptor. Journal of Immunology (Baltimore, Md. : 1950). 163: 5526-34. PMID 10553080  0.88
1998 Zajac AJ, Blattman JN, Murali-Krishna K, Sourdive DJ, Suresh M, Altman JD, Ahmed R. Viral immune evasion due to persistence of activated T cells without effector function. The Journal of Experimental Medicine. 188: 2205-13. PMID 9858507 DOI: 10.1084/jem.188.12.2205  0.88
1998 Zajac AJ, Murali-Krishna K, Blattman JN, Ahmed R. Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells. Current Opinion in Immunology. 10: 444-9. PMID 9722921 DOI: 10.1016/S0952-7915(98)80119-2  0.88
1998 Sourdive DJD, Murali-Krishna K, Altman JD, Zajac AJ, Whitmire JK, Pannetier C, Kourilsky P, Evavold B, Sette A, Ahmed R. Conserved T cell receptor repertoire in primary and memory CD8 T cell responses to an acute viral infection Journal of Experimental Medicine. 188: 71-82. PMID 9653085 DOI: 10.1084/jem.188.1.71  0.88
1998 Murali-Krishna K, Altman JD, Suresh M, Sourdive DJ, Zajac AJ, Miller JD, Slansky J, Ahmed R. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity. 8: 177-87. PMID 9491999 DOI: 10.1016/S1074-7613(00)80470-7  0.88
1997 Quinn DG, Zajac AJ, Hioe CE, Frelinger JA. Virus-specific, CD8+ major histocompatibility complex class I- restricted cytotoxic T lymphocytes in lymphocytic choriomeningitis virus- infected β2-microglobulin-deficient mice Journal of Virology. 71: 8392-8396. PMID 9343195 DOI: 10.1128/jvi.71.11.8392-8396.1997  0.88
1996 Zajac AJ, Quinn DG, Cohen PL, Frelinger JA. Fas-dependent CD4+ cytotoxic T-cell-mediated pathogenesis during virus infection Proceedings of the National Academy of Sciences of the United States of America. 93: 14730-14735. PMID 8962123  0.88
1995 Quinn DG, Zajac AJ, Frelinger JA. The cell-mediated immune response against lymphocytic choriomeningitis virus in β2-microglobulin deficient mice Immunological Reviews. 151-169. PMID 8825286  0.88
1995 Zajac AJ, Muller D, Pederson K, Frelinger JA, Quinn DG. Natural killer cell activity in lymphocytic choriomeningitis virus-infected β2-microglobulin-deficient mice International Immunology. 7: 1545-1556. PMID 8562499 DOI: 10.1093/intimm/7.10.1545  0.88
1995 Davis NL, Brown KW, Greenwald GF, Zajac AJ, Zacny VL, Smith JF, Johnston RE. Attenuated mutants of Venezuelan equine encephalitis virus containing lethal mutations in the PE2 cleavage signal combined with a second-site suppressor mutation in E1. Virology. 212: 102-10. PMID 7676619 DOI: 10.1006/viro.1995.1458  0.88
1994 Brown EA, Zajac AJ, Lemon SM. In vitro characterization of an internal ribosomal entry site (IRES) present within the 5′ nontranslated region of hepatitis A virus RNA: Comparison with the IRES of encephalomyocarditis virus Journal of Virology. 68: 1066-1074. PMID 8289336 DOI: 10.1128/jvi.68.2.1066-1074.1994  0.88
1993 Quinn DG, Zajac AJ, Frelinger JA, Muller D. Transfer of lymphocytic choriomeningitis disease in β2-microglobulin-deficient mice by CD4+ T cells International Immunology. 5: 1193-1198. PMID 7903551 DOI: 10.1093/intimm/5.10.1193  0.88
1992 Caravokyri C, Zajac AJ, Pringle CR. Assignment of mutant tsN19 (complementation group E) of respiratory syncytial virus to the P protein gene Journal of General Virology. 73: 865-873. PMID 1378878  0.88
1991 Zajac AJ, Amphlett EM, Rowlands DJ, Sangar DV. Parameters influencing the attachment of hepatitis A virus to a variety of continuous cell lines Journal of General Virology. 72: 1667-1675. PMID 1649900  0.88
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