Douglas J. Perkins - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Microbiology Biology

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Anyona SB, Hengartner NW, Raballah E, Ong'echa JM, Lauve N, Cheng Q, Fenimore PW, Ouma C, Lambert CG, McMahon BH, Perkins DJ. Cyclooxygenase-2 haplotypes influence the longitudinal risk of malaria and severe malarial anemia in Kenyan children from a holoendemic transmission region. Journal of Human Genetics. PMID 31664161 DOI: 10.1038/s10038-019-0692-3  0.52
2019 Kisia LE, Kempaiah P, Anyona SB, Munde EO, Achieng AO, Ong'echa JM, Lambert CG, Chelimo K, Ouma C, Perkins DJ, Raballah E. Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum. Bmc Medical Genetics. 20: 140. PMID 31420016 DOI: 10.1186/s12881-019-0866-z  0.52
2019 Achieng AO, Hengartner NW, Raballah E, Cheng Q, Anyona SB, Lauve N, Guyah B, Foo-Hurwitz I, Ong'echa JM, McMahon BH, Ouma C, Lambert CG, Perkins DJ. Integrated OMICS platforms identify LAIR1 genetic variants as novel predictors of cross-sectional and longitudinal susceptibility to severe malaria and all-cause mortality in Kenyan children. Ebiomedicine. PMID 31278068 DOI: 10.1016/j.ebiom.2019.06.043  0.52
2019 Achieng AO, Guyah B, Cheng Q, Ong'echa JM, Ouma C, Lambert CG, Perkins DJ. Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling. Ebiomedicine. PMID 31257148 DOI: 10.1016/j.ebiom.2019.06.040  0.52
2019 Kubicek-Sutherland JZ, Vu DM, Noormohamed A, Mendez HM, Stromberg LR, Pedersen CA, Hengartner AC, Klosterman KE, Bridgewater HA, Otieno V, Cheng Q, Anyona SB, Ouma C, Raballah E, Perkins DJ, et al. Direct detection of bacteremia by exploiting host-pathogen interactions of lipoteichoic acid and lipopolysaccharide. Scientific Reports. 9: 6203. PMID 30996333 DOI: 10.1038/s41598-019-42502-5  0.36
2017 Kumar P, Achieng AO, Rajendran V, Ghosh PC, Singh BK, Rawat M, Perkins DJ, Kempaiah P, Rathi B. Synergistic blending of high-valued heterocycles inhibits growth of Plasmodium falciparum in culture and P. berghei infection in mouse model. Scientific Reports. 7: 6724. PMID 28751747 DOI: 10.1038/s41598-017-06097-z  0.52
2017 Munde EO, Okeyo WA, Raballah E, Anyona SB, Were T, Ong'echa JM, Perkins DJ, Ouma C. Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya. Bmc Infectious Diseases. 17: 289. PMID 28427365 DOI: 10.1186/s12879-017-2390-0  0.52
2017 Munde EO, Raballah E, Okeyo WA, Ong'echa JM, Perkins DJ, Ouma C. Haplotype of non-synonymous mutations within IL-23R is associated with susceptibility to severe malaria anemia in a P. falciparum holoendemic transmission area of Kenya. Bmc Infectious Diseases. 17: 291. PMID 28427357 DOI: 10.1186/s12879-017-2404-y  0.52
2017 Raballah E, Kempaiah P, Karim Z, Orinda GO, Otieno MF, Perkins DJ, Ong'echa JM. CD4 T-cell expression of IFN-γ and IL-17 in pediatric malarial anemia. Plos One. 12: e0175864. PMID 28426727 DOI: 10.1371/journal.pone.0175864  0.52
2017 Achieng AO, Rawat M, Ogutu B, Guyah B, Ong Echa JM, Perkins DJ, Kempaiah P. Antimalarials: Molecular Drug Targets And Mechanism of Action. Current Topics in Medicinal Chemistry. PMID 28137233  0.52
2016 Kempaiah P, Dokladny K, Karim Z, Raballah E, Ong'echa JM, Moseley PL, Perkins DJ. Reduced Hsp70 and Glutamine in Pediatric Severe Malaria Anemia: Role of Hemozoin in Suppressing Hsp70 and NF-κB activation. Molecular Medicine (Cambridge, Mass.). PMID 27579474 DOI: 10.2119/molmed.2016.00130  0.52
2016 Davenport GC, Hittner JB, Otieno V, Karim Z, Mukundan H, Fenimore PW, Hengartner NW, McMahon BH, Kempaiah P, Ong'echa JM, Perkins DJ. Reduced Parasite Burden in Children with Falciparum Malaria and Bacteremia Coinfections: Role of Mediators of Inflammation. Mediators of Inflammation. 2016: 4286576. PMID 27418744 DOI: 10.1155/2016/4286576  0.52
2015 Lalremruata A, Magris M, Vivas-Martínez S, Koehler M, Esen M, Kempaiah P, Jeyaraj S, Perkins DJ, Mordmüller B, Metzger WG. Natural infection of Plasmodium brasilianum in humans: Man and monkey share quartan malaria parasites in the Venezuelan Amazon. Ebiomedicine. 2: 1186-92. PMID 26501116 DOI: 10.1016/j.ebiom.2015.07.033  0.52
2014 Ogutu BR, Onyango KO, Koskei N, Omondi EK, Ongecha JM, Otieno GA, Obonyo C, Otieno L, Eyase F, Johnson JD, Omollo R, Perkins DJ, Akhwale W, Juma E. Efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children aged less than five years: results of an open-label, randomized, single-centre study. Malaria Journal. 13: 33. PMID 24472156 DOI: 10.1186/1475-2875-13-33  0.52
2013 Anyona SB, Kempaiah P, Davenport GC, Vulule JM, Hittner JB, Ong'echa JM, Perkins DJ. Suppressed circulating bicyclo-PGE2 levels and leukocyte COX-2 transcripts in children co-infected with P. falciparum malaria and HIV-1 or bacteremia. Biochemical and Biophysical Research Communications. 436: 585-90. PMID 23743193 DOI: 10.1016/j.bbrc.2013.05.089  0.52
2013 Okeyo WA, Munde EO, Okumu W, Raballah E, Anyona SB, Vulule JM, Ong'echa JM, Perkins DJ, Ouma C. Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels. Bmc Immunology. 14: 15. PMID 23521898 DOI: 10.1186/1471-2172-14-15  0.52
2013 Rivas AL, Jankowski MD, Piccinini R, Leitner G, Schwarz D, Anderson KL, Fair JM, Hoogesteijn AL, Wolter W, Chaffer M, Blum S, Were T, Konah SN, Kempaiah P, Ong'echa JM, ... ... Perkins DJ, et al. Feedback-based, system-level properties of vertebrate-microbial interactions. Plos One. 8: e53984. PMID 23437039 DOI: 10.1371/journal.pone.0053984  0.52
2013 Kempaiah P, Davidson LB, Perkins DJ, Byrd TF. Cystic fibrosis CFBE41o- cells contain TLR1 SNP I602S and fail to respond to Mycobacterium abscessus. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 12: 773-9. PMID 23403223 DOI: 10.1016/j.jcf.2013.01.001  0.52
2013 Perkins DJ, Were T, Anyona S, Hittner JB, Kempaiah P, Davenport GC, Ong'echa JM. The global burden of severe falciparum Malaria: An immunological and genetic perspective on pathogenesis Dynamic Models of Infectious Diseases. 1: 231-283. DOI: 10.1007/978-1-4614-3961-5_8  0.52
2013 Yasnot MF, Perkins DJ, Corredor M, Yanow S, Carmona-Fonseca J, Elena Maestre A. The effects of Plasmodium vivax gestational malaria on the clinical and immune status of pregnant women in Northwestern Colombia Colombia Medica. 44: 172-177.  0.52
2012 Rivas AL, Fasina FO, Hoogesteyn AL, Konah SN, Febles JL, Perkins DJ, Hyman JM, Fair JM, Hittner JB, Smith SD. Connecting network properties of rapidly disseminating epizoonotics. Plos One. 7: e39778. PMID 22761900 DOI: 10.1371/journal.pone.0039778  0.52
2012 Anyona SB, Kempaiah P, Raballah E, Davenport GC, Were T, Konah SN, Vulule JM, Hittner JB, Gichuki CW, Ong'echa JM, Perkins DJ. Reduced systemic bicyclo-prostaglandin-E2 and cyclooxygenase-2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia. American Journal of Hematology. 87: 782-9. PMID 22730036 DOI: 10.1002/ajh.23253  0.52
2012 Davenport GC, Hittner JB, Were T, Ong'echa JM, Perkins DJ. Relationship between inflammatory mediator patterns and anemia in HIV-1 positive and exposed children with Plasmodium falciparum malaria. American Journal of Hematology. 87: 652-8. PMID 22570198 DOI: 10.1002/ajh.23200  0.52
2012 Kempaiah P, Anyona SB, Raballah E, Davenport GC, Were T, Hittner JB, Ong'echa JM, Perkins DJ. Reduced interferon (IFN)-α conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality. Human Genetics. 131: 1375-91. PMID 22570109 DOI: 10.1007/s00439-012-1175-1  0.52
2012 Badu K, Afrane YA, Larbi J, Stewart VA, Waitumbi J, Angov E, Ong'echa JM, Perkins DJ, Zhou G, Githeko A, Yan G. Marked variation in MSP-119 antibody responses to malaria in western Kenyan highlands. Bmc Infectious Diseases. 12: 50. PMID 22380785 DOI: 10.1186/1471-2334-12-50  0.52
2012 Rivas AL, Fasina FO, Hammond JM, Smith SD, Hoogesteijn AL, Febles JL, Hittner JB, Perkins DJ. Epidemic protection zones: centred on cases or based on connectivity? Transboundary and Emerging Diseases. 59: 464-9. PMID 22360843 DOI: 10.1111/j.1865-1682.2011.01301.x  0.52
2012 Ouma C, Davenport GC, Garcia S, Kempaiah P, Chaudhary A, Were T, Anyona SB, Raballah E, Konah SN, Hittner JB, Vulule JM, Ong'echa JM, Perkins DJ. Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children. Human Genetics. 131: 289-99. PMID 21818580 DOI: 10.1007/s00439-011-1076-8  0.52
2011 Davidson LB, Nessar R, Kempaiah P, Perkins DJ, Byrd TF. Mycobacterium abscessus glycopeptidolipid prevents respiratory epithelial TLR2 signaling as measured by HβD2 gene expression and IL-8 release. Plos One. 6: e29148. PMID 22216191 DOI: 10.1371/journal.pone.0029148  0.52
2011 Perkins DJ, Were T, Davenport GC, Kempaiah P, Hittner JB, Ong'echa JM. Severe malarial anemia: innate immunity and pathogenesis. International Journal of Biological Sciences. 7: 1427-42. PMID 22110393  0.52
2011 Anyona SB, Kempaiah P, Raballah E, Ouma C, Were T, Davenport GC, Konah SN, Vulule JM, Hittner JB, Gichuki CW, Ong'echa JM, Perkins DJ. Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality. Infection and Immunity. 79: 4923-32. PMID 21969001 DOI: 10.1128/IAI.05601-11  0.52
2011 Ong'echa JM, Davenport GC, Vulule JM, Hittner JB, Perkins DJ. Identification of inflammatory biomarkers for pediatric malarial anemia severity using novel statistical methods. Infection and Immunity. 79: 4674-80. PMID 21859849 DOI: 10.1128/IAI.05161-11  0.52
2011 Ong'echa JM, Raballah EO, Kempaiah PM, Anyona SB, Were T, Davenport GC, Konah S, Vulule JM, Ouma C, Hittner JB, Perkins DJ. Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria. Bmc Genetics. 12: 69. PMID 21819616 DOI: 10.1186/1471-2156-12-69  0.52
2011 Awandare GA, Kempaiah P, Ochiel DO, Piazza P, Keller CC, Perkins DJ. Mechanisms of erythropoiesis inhibition by malarial pigment and malaria-induced proinflammatory mediators in an in vitro model. American Journal of Hematology. 86: 155-62. PMID 21264897 DOI: 10.1002/ajh.21933  0.52
2011 Were T, Davenport GC, Hittner JB, Ouma C, Vulule JM, Ong'echa JM, Perkins DJ. Bacteremia in Kenyan children presenting with malaria. Journal of Clinical Microbiology. 49: 671-6. PMID 21106789 DOI: 10.1128/JCM.01864-10  0.52
2010 Novelli EM, Hittner JB, Davenport GC, Ouma C, Were T, Obaro S, Kaplan S, Ong'echa JM, Perkins DJ. Clinical predictors of severe malarial anaemia in a holoendemic Plasmodium falciparum transmission area. British Journal of Haematology. 149: 711-21. PMID 20408849 DOI: 10.1111/j.1365-2141.2010.08147.x  0.52
2010 Davenport GC, Ouma C, Hittner JB, Were T, Ouma Y, Ong'echa JM, Perkins DJ. Hematological predictors of increased severe anemia in Kenyan children coinfected with Plasmodium falciparum and HIV-1. American Journal of Hematology. 85: 227-33. PMID 20196168 DOI: 10.1002/ajh.21653  0.52
2010 Ouma C, Keller CC, Davenport GC, Were T, Konah S, Otieno MF, Hittner JB, Vulule JM, Martinson J, Ong'echa JM, Ferrell RE, Perkins DJ. A novel functional variant in the stem cell growth factor promoter protects against severe malarial anemia. Infection and Immunity. 78: 453-60. PMID 19884328 DOI: 10.1128/IAI.00895-09  0.52
2010 Phawong C, Ouma C, Tangteerawatana P, Thongshoob J, Were T, Mahakunkijcharoen Y, Wattanasirichaigoon D, Perkins DJ, Khusmith S. Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults Immunogenetics. 62: 345-356. DOI: 10.1007/s00251-010-0439-y  0.52
2009 Awandare GA, Martinson JJ, Were T, Ouma C, Davenport GC, Ong'echa JM, Wang W, Leng L, Ferrell RE, Bucala R, Perkins DJ. MIF (macrophage migration inhibitory factor) promoter polymorphisms and susceptibility to severe malarial anemia. The Journal of Infectious Diseases. 200: 629-37. PMID 19591577 DOI: 10.1086/600894  0.52
2009 Keller CC, Ouma C, Ouma Y, Awandare GA, Davenport GC, Were T, Hittner JB, Vulule JM, Ong'echa JM, Perkins DJ. Suppression of a novel hematopoietic mediator in children with severe malarial anemia. Infection and Immunity. 77: 3864-71. PMID 19528216 DOI: 10.1128/IAI.00342-09  0.52
2009 Were T, Davenport GC, Yamo EO, Hittner JB, Awandare GA, Otieno MF, Ouma C, Orago AS, Vulule JM, Ong'echa JM, Perkins DJ. Naturally acquired hemozoin by monocytes promotes suppression of RANTES in children with malarial anemia through an IL-10-dependent mechanism. Microbes and Infection / Institut Pasteur. 11: 811-9. PMID 19427395 DOI: 10.1016/j.micinf.2009.04.021  0.52
2008 Ouma C, Davenport GC, Were T, Otieno MF, Hittner JB, Vulule JM, Martinson J, Ong'echa JM, Ferrell RE, Perkins DJ. Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production. Human Genetics. 124: 515-24. PMID 18972133 DOI: 10.1007/s00439-008-0578-5  0.52
2008 Ouma C, Davenport GC, Awandare GA, Keller CC, Were T, Otieno MF, Vulule JM, Martinson J, Ong'echa JM, Ferrell RE, Perkins DJ. Polymorphic variability in the interleukin (IL)-1beta promoter conditions susceptibility to severe malarial anemia and functional changes in IL-1beta production. The Journal of Infectious Diseases. 198: 1219-26. PMID 18781863 DOI: 10.1086/592055  0.52
2008 Ong'echa JM, Remo AM, Kristoff J, Hittner JB, Were T, Ouma C, Otieno RO, Vulule JM, Keller CC, Awandare GA, Perkins DJ. Increased circulating interleukin (IL)-23 in children with malarial anemia: in vivo and in vitro relationship with co-regulatory cytokines IL-12 and IL-10. Clinical Immunology (Orlando, Fla.). 126: 211-21. PMID 17945537 DOI: 10.1016/j.clim.2007.08.007  0.52
2007 Awandare GA, Kremsner PG, Hittner JB, Keller CC, Clark IA, Weinberg JB, Perkins DJ. Higher production of peripheral blood macrophage migration inhibitory factor in healthy children with a history of mild malaria relative to children with a history of severe malaria. The American Journal of Tropical Medicine and Hygiene. 76: 1033-6. PMID 17556607  0.52
2007 Awandare GA, Ouma Y, Ouma C, Were T, Otieno R, Keller CC, Davenport GC, Hittner JB, Vulule J, Ferrell R, Ong'echa JM, Perkins DJ. Role of monocyte-acquired hemozoin in suppression of macrophage migration inhibitory factor in children with severe malarial anemia. Infection and Immunity. 75: 201-10. PMID 17060471 DOI: 10.1128/IAI.01327-06  0.52
2006 Were T, Hittner JB, Ouma C, Otieno RO, Orago AS, Ong'echa JM, Vulule JM, Keller CC, Perkins DJ. Suppression of RANTES in children with Plasmodium falciparum malaria. Haematologica. 91: 1396-9. PMID 17018392  0.52
2006 Awandare GA, Ouma C, Keller CC, Were T, Otieno R, Ouma Y, Davenport GC, Hittner JB, Ong'echa JM, Ferrell R, Perkins DJ. A macrophage migration inhibitory factor promoter polymorphism is associated with high-density parasitemia in children with malaria. Genes and Immunity. 7: 568-75. PMID 16929348 DOI: 10.1038/sj.gene.6364332  0.52
2006 Keller CC, Yamo O, Ouma C, Ong'echa JM, Ounah D, Hittner JB, Vulule JM, Perkins DJ. Acquisition of hemozoin by monocytes down-regulates interleukin-12 p40 (IL-12p40) transcripts and circulating IL-12p70 through an IL-10-dependent mechanism: in vivo and in vitro findings in severe malarial anemia. Infection and Immunity. 74: 5249-60. PMID 16926419 DOI: 10.1128/IAI.00843-06  0.52
2006 Keller CC, Davenport GC, Dickman KR, Hittner JB, Kaplan SS, Weinberg JB, Kremsner PG, Perkins DJ. Suppression of prostaglandin E2 by malaria parasite products and antipyretics promotes overproduction of tumor necrosis factor-alpha: association with the pathogenesis of childhood malarial anemia. The Journal of Infectious Diseases. 193: 1384-93. PMID 16619186 DOI: 10.1086/503047  0.52
2006 Ouma C, Keller CC, Opondo DA, Were T, Otieno RO, Otieno MF, Orago AS, Ong'Echa JM, Vulule JM, Ferrell RE, Perkins DJ. Association of FCgamma receptor IIA (CD32) polymorphism with malarial anemia and high-density parasitemia in infants and young children. The American Journal of Tropical Medicine and Hygiene. 74: 573-7. PMID 16606986  0.52
2006 Ong'echa JM, Keller CC, Were T, Ouma C, Otieno RO, Landis-Lewis Z, Ochiel D, Slingluff JL, Mogere S, Ogonji GA, Orago AS, Vulule JM, Kaplan SS, Day RD, Perkins DJ. Parasitemia, anemia, and malarial anemia in infants and young children in a rural holoendemic Plasmodium falciparum transmission area. The American Journal of Tropical Medicine and Hygiene. 74: 376-85. PMID 16525094  0.52
2006 Otieno RO, Ouma C, Ong'echa JM, Keller CC, Were T, Waindi EN, Michaels MG, Day RD, Vulule JM, Perkins DJ. Increased severe anemia in HIV-1-exposed and HIV-1-positive infants and children during acute malaria. Aids (London, England). 20: 275-80. PMID 16511422 DOI: 10.1097/01.aids.0000200533.56490.b7  0.52
2006 Awandare GA, Hittner JB, Kremsner PG, Ochiel DO, Keller CC, Weinberg JB, Clark IA, Perkins DJ. Decreased circulating macrophage migration inhibitory factor (MIF) protein and blood mononuclear cell MIF transcripts in children with Plasmodium falciparum malaria. Clinical Immunology (Orlando, Fla.). 119: 219-25. PMID 16461006 DOI: 10.1016/j.clim.2005.12.003  0.52
2006 Riley EM, Wahl S, Perkins DJ, Schofield L. Regulating immunity to malaria Parasite Immunology. 28: 35-49. PMID 16438675 DOI: 10.1111/j.1365-3024.2006.00775.x  0.52
2006 Ouma C, Keller CC, Opondo DA, Were T, Otieno RO, Otieno MF, Orago ASS, Ong'echa JM, Vulule JM, Ferrell RE, Perkins DJ. Association of FCγ receptor IIA (CD32) polymorphism with malarial anemia and high-density parasitemia in infants and young children American Journal of Tropical Medicine and Hygiene. 74: 573-577.  0.52
2005 Nti BK, Slingluff JL, Keller CC, Hittner JB, Ong'echa JM, Murphey-Corb M, Perkins DJ. Stage-specific effects of Plasmodium falciparum-derived hemozoin on blood mononuclear cell TNF-alpha regulation and viral replication. Aids (London, England). 19: 1771-80. PMID 16227784  0.52
2005 Ochiel DO, Awandare GA, Keller CC, Hittner JB, Kremsner PG, Weinberg JB, Perkins DJ. Differential regulation of beta-chemokines in children with Plasmodium falciparum malaria. Infection and Immunity. 73: 4190-7. PMID 15972509 DOI: 10.1128/IAI.73.7.4190-4197.2005  0.52
2005 Perkins DJ, Hittner JB, Mwaikambo ED, Granger DL, Weinberg JB, Anstey NM. Impaired systemic production of prostaglandin E2 in children with cerebral malaria. The Journal of Infectious Diseases. 191: 1548-57. PMID 15809915 DOI: 10.1086/429332  0.52
2004 Moore JM, Chaisavaneeyakorn S, Perkins DJ, Othoro C, Otieno J, Nahlen BL, Shi YP, Udhayakumar V. Hemozoin differentially regulates proinflammatory cytokine production in human immunodeficiency virus-seropositive and -seronegative women with placental malaria. Infection and Immunity. 72: 7022-9. PMID 15557625 DOI: 10.1128/IAI.72.12.7022-7029.2004  0.52
2004 Keller CC, Hittner JB, Nti BK, Weinberg JB, Kremsner PG, Perkins DJ. Reduced peripheral PGE2 biosynthesis in Plasmodium falciparum malaria occurs through hemozoin-induced suppression of blood mononuclear cell cyclooxygenase-2 gene expression via an interleukin-10-independent mechanism. Molecular Medicine (Cambridge, Mass.). 10: 45-54. PMID 15502882  0.52
2004 Keller CC, Kremsner PG, Hittner JB, Misukonis MA, Weinberg JB, Perkins DJ. Elevated nitric oxide production in children with malarial anemia: hemozoin-induced nitric oxide synthase type 2 transcripts and nitric oxide in blood mononuclear cells. Infection and Immunity. 72: 4868-73. PMID 15271950 DOI: 10.1128/IAI.72.8.4868-4873.2004  0.52
2003 Perkins DJ, Moore JM, Otieno J, Shi YP, Nahlen BL, Udhayakumar V, Lal AA. In vivo acquisition of hemozoin by placental blood mononuclear cells suppresses PGE2, TNF-alpha, and IL-10. Biochemical and Biophysical Research Communications. 311: 839-46. PMID 14623257 DOI: 10.1016/j.bbrc.2003.10.073  0.52
2002 Chaisavaneeyakorn S, Moore JM, Otieno J, Chaiyaroj SC, Perkins DJ, Shi YP, Nahlen BL, Lal AA, Udhayakumar V. Immunity to placental malaria. III. Impairment of interleukin(IL)-12, not IL-18, and interferon-inducible protein-10 responses in the placental intervillous blood of human immunodeficiency virus/malaria-coinfected women. The Journal of Infectious Diseases. 185: 127-31. PMID 11756993 DOI: 10.1086/338013  0.52
2001 Kun JF, Mordmüller B, Perkins DJ, May J, Mercereau-Puijalon O, Alpers M, Weinberg JB, Kremsner PG. Nitric oxide synthase 2Lambaréné (G-954C), increased nitric oxide production, and protection against malaria Journal of Infectious Diseases. 184: 330-336. PMID 11443559 DOI: 10.1086/322037  0.52
2001 Perkins DJ, Kremsner PG, Brice Weinberg J. Inverse relationship of plasma prostaglandin E2 and blood mononuclear cell cyclooxygenase-2 with disease severity in children with Plasmodium falciparum malaria Journal of Infectious Diseases. 183: 113-118. PMID 11076710 DOI: 10.1086/317660  0.52
2000 Naik RS, Branch OH, Woods AS, Vijaykumar M, Perkins DJ, Nahlen BL, Lal AA, Cotter RJ, Costello CE, Ockenhouse CF, Davidson EA, Gowda DC. Glycosylphosphatidylinositol anchors of Plasmodium falciparum: molecular characterization and naturally elicited antibody response that may provide immunity to malaria pathogenesis. The Journal of Experimental Medicine. 192: 1563-76. PMID 11104799 DOI: 10.1084/jem.192.11.1563  0.52
2000 Perkins DJ, Weinberg JB, Kremsner PG. Reduced interleukin-12 and transforming growth factor-β1 in severe childhood malaria: Relationship of cytokine balance with disease severity Journal of Infectious Diseases. 182: 988-992. PMID 10950804 DOI: 10.1086/315762  0.52
2000 Luty AJ, Perkins DJ, Lell B, Schmidt-Ott R, Lehman LG, Luckner D, Greve B, Matousek P, Herbich K, Schmid D, Weinberg JB, Kremsner PG. Low interleukin-12 activity in severe Plasmodium falciparum malaria. Infection and Immunity. 68: 3909-15. PMID 10858202 DOI: 10.1128/IAI.68.7.3909-3915.2000  0.52
2000 Perkins DJ, Weinberg JB, Kremsner PG. Inverse relationship of plasma prostaglandin-E2 and blood mononuclear cell cyclooxygenase-2 with disease severity in children with plasmodium falciparum malaria Blood. 96.  0.52
2000 Brice Weinberg J, Perkins DJ, Granger DL, Kremsner PG, Anstey NM. Nitric oxide asa nonprotein regulator of hematopoietic cell proliferation and differentiation-relationship to malarial anemia Blood. 96.  0.52
1999 Levesque MC, Hobbs MR, Anstey NM, Vaughn TN, Chancellor JA, Pole A, Perkins DJ, Misukonis MA, Chanock SJ, Granger DL, Weinberg JB. Nitric oxide synthase type 2 promoter polymorphisms, nitric oxide production, and disease severity in Tanzanian children with malaria. The Journal of Infectious Diseases. 180: 1994-2002. PMID 10558957 DOI: 10.1086/315140  0.52
1999 Perkins DJ, Kremsner PG, Schmid D, Misukonis MA, Kelly MA, Weinberg JB. Blood mononuclear cell nitric oxide production and plasma cytokine levels in healthy gabonese children with prior mild or severe malaria Infection and Immunity. 67: 4977-4981. PMID 10456963  0.52
1999 Perkins DJ, Kniss DA. Blockade of nitric oxide formation down-regulates cyclooxygenase-2 and decreases PGE2 biosynthesis in macrophages Journal of Leukocyte Biology. 65: 792-799. PMID 10380901  0.52
1998 Perkins DJ, St Clair EW, Misukonis MA, Weinberg JB. Reduction of NOS2 overexpression in rheumatoid arthritis patients treated with anti-tumor necrosis factor a monoclonal antibody (cA2) Arthritis and Rheumatism. 41: 2205-2210. PMID 9870877 DOI: 10.1002/1529-0131(199812)41:12<2205::AID-ART16>3.0.CO;2-Q  0.52
1997 Perkins DJ, Kniss DA. Tumor necrosis factor-α promotes sustained cyclooxygenase-2 expression: Attenuation by dexamethasone and NSAIDs Prostaglandins. 54: 727-743. PMID 9440135 DOI: 10.1016/S0090-6980(97)00144-5  0.52
1997 Swaisgood CM, Zu HX, Perkins DJ, Wu S, Garver CL, Zimmerman PD, Iams JD, Kniss DA. Coordinate expression of inducible nitric oxide synthase and cyclooxygenase-2 genes in uterine tissues of endotoxin-treated pregnant mice American Journal of Obstetrics and Gynecology. 177: 1253-1262. PMID 9396926  0.52
1997 Sharara AI, Perkins DJ, Misukonis MA, Chan SU, Dominitz JA, Weinberg JB. Interferon (IFN)-α activation of human blood mononuclear cells in vitro and in vivo for nitric oxide synthase (NOS) type 2 mRNA and protein expression: Possible relationship of induced NOS2 to the anti-hepatitis C effects of IFN-α in vivo Journal of Experimental Medicine. 186: 1495-1502. PMID 9348307 DOI: 10.1084/jem.186.9.1495  0.52
1997 Perkins DJ, Kniss DA. Rapid and transient induction of cyclo-oxygenase 2 by epidermal growth factor in human amnion-derived WISH cells Biochemical Journal. 321: 677-681. PMID 9032453  0.52
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