Dean H. Kedes - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Microbiology Biology

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Grant MJ, Loftus MS, Stoja AP, Kedes DH, Smith MM. Superresolution microscopy reveals structural mechanisms driving the nanoarchitecture of a viral chromatin tether. Proceedings of the National Academy of Sciences of the United States of America. PMID 29610353 DOI: 10.1073/Pnas.1721638115  0.442
2017 Loftus MS, Verville N, Kedes DH. A conserved leucine zipper motif in gammaherpesvirus ORF52 is critical for distinct microtubule rearrangements. Journal of Virology. PMID 28615210 DOI: 10.1128/Jvi.00304-17  0.493
2014 Ellison TJ, Kedes DH. Variable episomal silencing of a recombinant herpesvirus renders its encoded GFP an unreliable marker of infection in primary cells. Plos One. 9: e111502. PMID 25402328 DOI: 10.1371/Journal.Pone.0111502  0.516
2014 Zhou ZH, Hui WH, Shah S, Jih J, O'Connor CM, Sherman MB, Kedes DH, Schein S. Four levels of hierarchical organization, including noncovalent chainmail, brace the mature tumor herpesvirus capsid against pressurization. Structure (London, England : 1993). 22: 1385-98. PMID 25220471 DOI: 10.1016/J.Str.2014.05.019  0.55
2014 Anderson MS, Loftus MS, Kedes DH. Maturation and vesicle-mediated egress of primate gammaherpesvirus rhesus monkey rhadinovirus require inner tegument protein ORF52. Journal of Virology. 88: 9111-28. PMID 24899183 DOI: 10.1128/Jvi.01502-14  0.407
2014 Woodson EN, Anderson MS, Loftus MS, Kedes DH. Progressive accumulation of activated ERK2 within highly stable ORF45-containing nuclear complexes promotes lytic gammaherpesvirus infection. Plos Pathogens. 10: e1004066. PMID 24722398 DOI: 10.1371/Journal.Ppat.1004066  0.423
2012 Borah S, Nichols LA, Hassman LM, Kedes DH, Steitz JA. Tracking expression and subcellular localization of RNA and protein species using high-throughput single cell imaging flow cytometry. Rna (New York, N.Y.). 18: 1573-9. PMID 22745225 DOI: 10.1261/Rna.033126.112  0.715
2012 Woodson EN, Kedes DH. Distinct roles for extracellular signal-regulated kinase 1 (ERK1) and ERK2 in the structure and production of a primate gammaherpesvirus. Journal of Virology. 86: 9721-36. PMID 22740395 DOI: 10.1128/Jvi.00695-12  0.427
2011 Nichols LA, Adang LA, Kedes DH. Rapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug. Plos One. 6: e14535. PMID 21264294 DOI: 10.1371/Journal.Pone.0014535  0.7
2011 Hassman LM, Ellison TJ, Kedes DH. KSHV infects a subset of human tonsillar B cells, driving proliferation and plasmablast differentiation. The Journal of Clinical Investigation. 121: 752-68. PMID 21245574 DOI: 10.1172/Jci44185  0.746
2008 Deng B, O'Connor CM, Kedes DH, Zhou ZH. Cryo-electron tomography of Kaposi's sarcoma-associated herpesvirus capsids reveals dynamic scaffolding structures essential to capsid assembly and maturation. Journal of Structural Biology. 161: 419-27. PMID 18164626 DOI: 10.1016/J.Jsb.2007.10.016  0.561
2007 Adang LA, Tomescu C, Law WK, Kedes DH. Intracellular Kaposi's sarcoma-associated herpesvirus load determines early loss of immune synapse components. Journal of Virology. 81: 5079-90. PMID 17329329 DOI: 10.1128/Jvi.02738-06  0.731
2007 Deng B, O'Connor CM, Kedes DH, Zhou ZH. Direct visualization of the putative portal in the Kaposi's sarcoma-associated herpesvirus capsid by cryoelectron tomography. Journal of Virology. 81: 3640-4. PMID 17215290 DOI: 10.1128/Jvi.02254-06  0.536
2007 O'Connor CM, Kedes DH. Rhesus monkey rhadinovirus: a model for the study of KSHV. Current Topics in Microbiology and Immunology. 312: 43-69. PMID 17089793 DOI: 10.1007/978-3-540-34344-8_2  0.65
2006 Adang LA, Parsons CH, Kedes DH. Asynchronous progression through the lytic cascade and variations in intracellular viral loads revealed by high-throughput single-cell analysis of Kaposi's sarcoma-associated herpesvirus infection. Journal of Virology. 80: 10073-82. PMID 17005685 DOI: 10.1128/Jvi.01156-06  0.722
2006 Parsons CH, Adang LA, Overdevest J, O'Connor CM, Taylor JR, Camerini D, Kedes DH. KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice. The Journal of Clinical Investigation. 116: 1963-73. PMID 16794734 DOI: 10.1172/Jci27249  0.739
2006 O'Connor CM, Kedes DH. Mass spectrometric analyses of purified rhesus monkey rhadinovirus reveal 33 virion-associated proteins. Journal of Virology. 80: 1574-83. PMID 16415032 DOI: 10.1128/Jvi.80.3.1574-1583.2006  0.613
2005 Woodberry T, Suscovich TJ, Henry LM, Martin JN, Dollard S, O'Connor PG, Davis JK, Osmond D, Lee TH, Kedes DH, Khatri A, Lee J, Walker BD, Scadden DT, Brander C. Impact of Kaposi sarcoma-associated herpesvirus (KSHV) burden and HIV coinfection on the detection of T cell responses to KSHV ORF73 and ORF65 proteins. The Journal of Infectious Diseases. 192: 622-9. PMID 16028131 DOI: 10.1086/432103  0.423
2004 Parsons CH, Szomju B, Kedes DH. Susceptibility of human fetal mesenchymal stem cells to Kaposi sarcoma-associated herpesvirus. Blood. 104: 2736-8. PMID 15238422 DOI: 10.1182/Blood-2004-02-0693  0.417
2004 Renne R, Dittmer D, Kedes D, Schmidt K, Desrosiers RC, Luciw PA, Ganem D. Experimental transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) to SIV-positive and SIV-negative rhesus macaques. Journal of Medical Primatology. 33: 1-9. PMID 15061726 DOI: 10.1046/J.1600-0684.2003.00043.X  0.459
2003 O'Connor CM, Damania B, Kedes DH. De novo infection with rhesus monkey rhadinovirus leads to the accumulation of multiple intranuclear capsid species during lytic replication but favors the release of genome-containing virions. Journal of Virology. 77: 13439-47. PMID 14645602 DOI: 10.1128/Jvi.77.24.13439-13447.2003  0.643
2003 Yu XK, O'Connor CM, Atanasov I, Damania B, Kedes DH, Zhou ZH. Three-dimensional structures of the A, B, and C capsids of rhesus monkey rhadinovirus: insights into gammaherpesvirus capsid assembly, maturation, and DNA packaging. Journal of Virology. 77: 13182-93. PMID 14645575 DOI: 10.1128/Jvi.77.24.13182-13193.2003  0.541
2003 Tomescu C, Law WK, Kedes DH. Surface downregulation of major histocompatibility complex class I, PE-CAM, and ICAM-1 following de novo infection of endothelial cells with Kaposi's sarcoma-associated herpesvirus. Journal of Virology. 77: 9669-84. PMID 12915579 DOI: 10.1128/Jvi.77.17.9669-9684.2003  0.742
2003 Whitby D, Stossel A, Gamache C, Papin J, Bosch M, Smith A, Kedes DH, White G, Kennedy R, Dittmer DP. Novel Kaposi's sarcoma-associated herpesvirus homolog in baboons. Journal of Virology. 77: 8159-65. PMID 12829855 DOI: 10.1128/Jvi.77.14.8159-8165.2003  0.43
2003 Biggar RJ, Engels EA, Whitby D, Kedes DH, Goedert JJ. Antibody reactivity to latent and lytic antigens to human herpesvirus-8 in longitudinally followed homosexual men. The Journal of Infectious Diseases. 187: 12-8. PMID 12508141 DOI: 10.1086/345866  0.383
2002 Brander C, Raje N, O'Connor PG, Davies F, Davis J, Chauhan D, Hideshima T, Martin J, Osmond D, Kedes DH, Walker BD, Scadden DT, Anderson KC. Absence of biologically important Kaposi sarcoma-associated herpesvirus gene products and virus-specific cellular immune responses in multiple myeloma. Blood. 100: 698-700. PMID 12091368 DOI: 10.1182/Blood.V100.2.698  0.425
2001 Brander C, O'Connor P, Suscovich T, Jones NG, Lee Y, Kedes D, Ganem D, Martin J, Osmond D, Southwood S, Sette A, Walker BD, Scadden DT. Definition of an optimal cytotoxic T lymphocyte epitope in the latently expressed Kaposi's sarcoma-associated herpesvirus kaposin protein. The Journal of Infectious Diseases. 184: 119-26. PMID 11424007 DOI: 10.1086/322003  0.456
2001 Trus BL, Heymann JB, Nealon K, Cheng N, Newcomb WW, Brown JC, Kedes DH, Steven AC. Capsid structure of Kaposi's sarcoma-associated herpesvirus, a gammaherpesvirus, compared to those of an alphaherpesvirus, herpes simplex virus type 1, and a betaherpesvirus, cytomegalovirus. Journal of Virology. 75: 2879-90. PMID 11222713 DOI: 10.1128/Jvi.75.6.2879-2890.2001  0.395
2001 Nealon K, Newcomb WW, Pray TR, Craik CS, Brown JC, Kedes DH. Lytic replication of Kaposi's sarcoma-associated herpesvirus results in the formation of multiple capsid species: isolation and molecular characterization of A, B, and C capsids from a gammaherpesvirus. Journal of Virology. 75: 2866-78. PMID 11222712 DOI: 10.1128/Jvi.75.6.2866-2878.2001  0.41
2000 Martin JN, Amad Z, Cossen C, Lam PK, Kedes DH, Page-Shafer KA, Osmond DH, Forghani B. Use of epidemiologically well-defined subjects and existing immunofluorescence assays to calibrate a new enzyme immunoassay for human herpesvirus 8 antibodies Journal of Clinical Microbiology. 38: 696-701. PMID 10655369 DOI: 10.1128/Jcm.38.2.696-701.2000  0.341
1999 O'Brien TR, Kedes D, Ganem D, Macrae DR, Rosenberg PS, Molden J, Goedert JJ. Evidence for concurrent epidemics of human herpesvirus 8 and human immunodeficiency virus type 1 in US homosexual men: rates, risk factors, and relationship to Kaposi's sarcoma. The Journal of Infectious Diseases. 180: 1010-7. PMID 10479125 DOI: 10.1086/315039  0.307
1998 Dittmer D, Kedes DH. Do viral chemokines modulate Kaposi's sarcoma? Bioessays. 20: 367-370. PMID 9670810 DOI: 10.1002/(Sici)1521-1878(199805)20:5<367::Aid-Bies3>3.0.Co;2-L  0.44
1998 Martin JN, Ganem DE, Osmond DH, Page-Shafer KA, Macrae D, Kedes DH. Sexual transmission and the natural history of human herpesvirus 8 infection. The New England Journal of Medicine. 338: 948-54. PMID 9521982 DOI: 10.1056/Nejm199804023381403  0.333
1998 O'Brien TR, Kedes D, Ganem D, Goedert JJ. HHV-8 Infection in Homosexual Men From New York City (NYC) and Washington (DC): Frequency, Risk Factors, and Relationship to Kaposi's Sarcoma (KS) Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 17: A25. DOI: 10.1097/00042560-199804010-00072  0.328
1997 Kedes DH, Lagunoff M, Renne R, Ganem D. Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus Journal of Clinical Investigation. 100: 2606-2610. PMID 9366576 DOI: 10.1172/Jci119804  0.467
1997 Diamond C, Huang ML, Kedes DH, Speck C, Rankin GW, Ganem D, Coombs RW, Rose TM, Krieger JN, Corey L. Absence of detectable human herpesvirus 8 in the semen of human immunodeficiency virus-infected men without Kaposi's sarcoma. The Journal of Infectious Diseases. 176: 775-7. PMID 9291331 DOI: 10.1086/517299  0.427
1997 Kedes DH, Ganem D. Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs: Implications for potential therapy Journal of Clinical Investigation. 99: 2082-2086. PMID 9151779 DOI: 10.1172/Jci119380  0.408
1997 Goedert JJ, Kedes DH, Ganem D. Antibodies to human herpesvirus 8 in women and infants born in Haiti and the USA Lancet. 349: 1368. PMID 9149705 DOI: 10.1016/S0140-6736(05)63204-7  0.309
1997 Kedes DH, Ganem D, Ameli N, Bacchetti P, Greenblatt R. The prevalence of serum antibody to human herpesvirus 8 (Kaposi sarcoma- associated herpesvirus) among HIV-seropositive and high-risk HIV-seronegative women Journal of the American Medical Association. 277: 478-481. PMID 9020272 DOI: 10.1001/Jama.1997.03540300046032  0.331
1996 Kedes DH, Operskalski E, Busch M, Kohn R, Flood J, Ganem D. The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): Distribution of infection in KS risk groups and evidence for sexual transmission Nature Medicine. 2: 918-924. PMID 8705863 DOI: 10.1038/Nm0896-918  0.37
1996 Renne R, Zhong W, Herndier B, McGrath M, Abbey N, Kedes D, Ganem D. Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture Nature Medicine. 2: 342-346. PMID 8612236 DOI: 10.1038/Nm0396-342  0.455
1987 Kedes DH, Steitz JA. Accurate 5' splice-site selection in mouse kappa immunoglobulin light chain premessenger RNAs is not cell-type-specific Proceedings of the National Academy of Sciences of the United States of America. 84: 7928-7932. PMID 3120179 DOI: 10.1073/Pnas.84.22.7928  0.302
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