Laurie H. Glimcher - Publications

Harvard University, Cambridge, MA, United States 
Immunology, Molecular Biology, Microbiology Biology

310 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Cubillos-Ruiz JR, Glimcher LH. Targeting abnormal ER stress responses in tumors: A new approach to cancer immunotherapy. Oncoimmunology. 5: e1098802. PMID 27141359 DOI: 10.1080/2162402X.2015.1098802  1
2016 Bettigole SE, Glimcher LH. Novel roles for XBP1 in hematopoietic development. Cell Cycle (Georgetown, Tex.). 0. PMID 27058464 DOI: 10.1080/15384101.2016.1172470  1
2016 Cubillos-Ruiz JR, Bettigole SE, Glimcher LH. Molecular Pathways: Immunosuppressive Roles of IRE1α-XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26979393 DOI: 10.1158/1078-0432.Ccr-15-1570  1
2016 Greenblatt MB, Shin DY, Oh H, Lee KY, Zhai B, Gygi SP, Lotinun S, Baron R, Liu D, Su B, Glimcher LH, Shim JH. MEKK2 mediates an alternative β-catenin pathway that promotes bone formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884171 DOI: 10.1073/Pnas.1600813113  1
2016 Martínez G, Vidal RL, Mardones P, Serrano FG, Ardiles AO, Wirth C, Valdés P, Thielen P, Schneider BL, Kerr B, Valdés JL, Palacios AG, Inestrosa NC, Glimcher LH, Hetz C. Regulation of Memory Formation by the Transcription Factor XBP1. Cell Reports. PMID 26854229 DOI: 10.1016/J.Celrep.2016.01.028  1
2015 Cameron TL, Bell KM, Gresshoff IL, Sampurno L, Mullan L, Ermann J, Glimcher LH, Boot-Handford RP, Bateman JF. XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease. Plos Genetics. 11: e1005505. PMID 26372225 DOI: 10.1371/Journal.Pgen.1005505  1
2015 Adoro S, Cubillos-Ruiz JR, Chen X, Deruaz M, Vrbanac VD, Song M, Park S, Murooka TT, Dudek TE, Luster AD, Tager AM, Streeck H, Bowman B, Walker BD, Kwon DS, ... ... Glimcher LH, et al. IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection. Nature Communications. 6: 7562. PMID 26108174 DOI: 10.1038/Ncomms8562  1
2015 Cubillos-Ruiz JR, Silberman PC, Rutkowski MR, Chopra S, Perales-Puchalt A, Song M, Zhang S, Bettigole SE, Gupta D, Holcomb K, Ellenson LH, Caputo T, Lee AH, Conejo-Garcia JR, Glimcher LH. ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis. Cell. 161: 1527-38. PMID 26073941 DOI: 10.1016/J.Cell.2015.05.025  1
2015 Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. Pillars article: A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 2000. 100: 655-669. Journal of Immunology (Baltimore, Md. : 1950). 194: 2961-75. PMID 25795787  1
2015 Cameron TL, Gresshoff IL, Bell KM, Piróg KA, Sampurno L, Hartley CL, Sanford EM, Wilson R, Ermann J, Boot-Handford RP, Glimcher LH, Briggs MD, Bateman JF. Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 23: 661-70. PMID 25600960 DOI: 10.1016/J.Joca.2015.01.001  1
2015 Bettigole SE, Glimcher LH. Endoplasmic reticulum stress in immunity. Annual Review of Immunology. 33: 107-38. PMID 25493331 DOI: 10.1146/Annurev-Immunol-032414-112116  1
2015 Greenblatt MB, Kim JM, Oh H, Park KH, Choo MK, Sano Y, Tye CE, Skobe Z, Davis RJ, Park JM, Bei M, Glimcher LH, Shim JH. p38α MAPK is required for tooth morphogenesis and enamel secretion. The Journal of Biological Chemistry. 290: 284-95. PMID 25406311 DOI: 10.1074/Jbc.M114.599274  1
2014 Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt MB, Hatziapostolou M, Lim E, Tam WL, Ni M, Chen Y, Mai J, Shen H, Hu DZ, Adoro S, Hu B, ... ... Glimcher LH, et al. XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway. Nature. 508: 103-7. PMID 24670641 DOI: 10.1038/Nature13119  1
2013 Greenblatt MB, Ritter SY, Wright J, Tsang K, Hu D, Glimcher LH, Aliprantis AO. NFATc1 and NFATc2 repress spontaneous osteoarthritis. Proceedings of the National Academy of Sciences of the United States of America. 110: 19914-9. PMID 24248346 DOI: 10.1073/Pnas.1320036110  1
2013 Lazarevic V, Glimcher LH, Lord GM. T-bet: A bridge between innate and adaptive immunity Nature Reviews Immunology. 13: 777-789. PMID 24113868 DOI: 10.1038/Nri3536  1
2013 Shim JH, Greenblatt MB, Zou W, Huang Z, Wein MN, Brady N, Hu D, Charron J, Brodkin HR, Petsko GA, Zaller D, Zhai B, Gygi S, Glimcher LH, Jones DC. Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts. The Journal of Clinical Investigation. 123: 4010-22. PMID 23945236 DOI: 10.1172/Jci69443  1
2013 Zou W, Greenblatt MB, Brady N, Lotinun S, Zhai B, de Rivera H, Singh A, Sun J, Gygi SP, Baron R, Glimcher LH, Jones DC. The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2. The Journal of Experimental Medicine. 210: 1793-806. PMID 23918955 DOI: 10.1084/Jem.20111790  1
2013 Greenblatt MB, Shim JH, Glimcher LH. Mitogen-activated protein kinase pathways in osteoblasts. Annual Review of Cell and Developmental Biology. 29: 63-79. PMID 23725048 DOI: 10.1146/Annurev-Cellbio-101512-122347  1
2013 Cho JA, Lee AH, Platzer B, Cross BC, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. Cell Host & Microbe. 13: 558-69. PMID 23684307 DOI: 10.1016/J.Chom.2013.03.011  1
2013 Park TY, Kim SH, Shin YC, Lee NH, Lee RK, Shim JH, Glimcher LH, Mook-Jung I, Cheong E, Kim WK, Honda F, Morio T, Lim JS, Lee SK. Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin. Journal of Controlled Release : Official Journal of the Controlled Release Society. 166: 307-15. PMID 23298615 DOI: 10.1016/J.Jconrel.2012.12.022  1
2013 Greenblatt MB, Shim JH, Zou W, Glimcher LH. A Tak1/p38 signaling axis regulates Runx2 activity and osteoblast functions Osteoimmunology: Interactions of the Immune and Skeletal Systems. 49-56. DOI: 10.1007/978-1-4614-5366-6_6  1
2012 So JS, Hur KY, Tarrio M, Ruda V, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Lichtman AH, Iwawaki T, Glimcher LH, Lee AH. Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. Cell Metabolism. 16: 487-99. PMID 23040070 DOI: 10.1016/J.Cmet.2012.09.004  1
2012 Ermann J, Glimcher LH. After GWAS: mice to the rescue? Current Opinion in Immunology. 24: 564-70. PMID 23031443 DOI: 10.1016/J.Coi.2012.09.005  1
2012 Fu W, Ergun A, Lu T, Hill JA, Haxhinasto S, Fassett MS, Gazit R, Adoro S, Glimcher L, Chan S, Kastner P, Rossi D, Collins JJ, Mathis D, Benoist C. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nature Immunology. 13: 972-80. PMID 22961053 DOI: 10.1038/Ni.2420  1
2012 Wein MN, Jones DC, Shim JH, Aliprantis AO, Sulyanto R, Lazarevic V, Poliachik SL, Gross TS, Glimcher LH. Control of bone resorption in mice by Schnurri-3. Proceedings of the National Academy of Sciences of the United States of America. 109: 8173-8. PMID 22573816 DOI: 10.1073/Pnas.1205848109  1
2012 Glimcher LH, Lindvall O, Aguirre V, Topalian SL, Musunuru K, Fauci AS. Translating research into therapies. Cell. 148: 1077-8. PMID 22532970 DOI: 10.1016/j.cell.2012.02.036  1
2012 Vidal RL, Figueroa A, Court FA, Thielen P, Molina C, Wirth C, Caballero B, Kiffin R, Segura-Aguilar J, Cuervo AM, Glimcher LH, Hetz C. Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy. Human Molecular Genetics. 21: 2245-62. PMID 22337954 DOI: 10.1093/Hmg/Dds040  1
2012 Hu Y, Park KK, Yang L, Wei X, Yang Q, Cho KS, Thielen P, Lee AH, Cartoni R, Glimcher LH, Chen DF, He Z. Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells. Neuron. 73: 445-52. PMID 22325198 DOI: 10.1016/J.Neuron.2011.11.026  1
2012 Greenblatt MB, Sargent JL, Farina G, Tsang K, Lafyatis R, Glimcher LH, Whitfield ML, Aliprantis AO. Interspecies comparison of human and murine scleroderma reveals IL-13 and CCL2 as disease subset-specific targets. The American Journal of Pathology. 180: 1080-94. PMID 22245215 DOI: 10.1016/J.Ajpath.2011.11.024  1
2012 Shim JH, Greenblatt MB, Singh A, Brady N, Hu D, Drapp R, Ogawa W, Kasuga M, Noda T, Yang SH, Lee SK, Rebel VI, Glimcher LH. Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice. The Journal of Clinical Investigation. 122: 91-106. PMID 22133875 DOI: 10.1172/Jci59466  1
2012 Jurczak MJ, Lee AH, Jornayvaz FR, Lee HY, Birkenfeld AL, Guigni BA, Kahn M, Samuel VT, Glimcher LH, Shulman GI. Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice. The Journal of Biological Chemistry. 287: 2558-67. PMID 22128176 DOI: 10.1074/Jbc.M111.316760  1
2012 Shim JH, Greenblatt MB, Singh A, Brady N, Hu D, Drapp R, Ogawa W, Kasuga M, Noda T, Yang SH, Lee SK, Rebel VI, Glimcher LH. Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice (Journal of Clinical Investigation (2012) 122, 1 (91-106) DOI: 10.1172/JCI59466) Journal of Clinical Investigation. 122: 1948. DOI: 10.1172/Jci63413  1
2011 Wan L, Zou W, Gao D, Inuzuka H, Fukushima H, Berg AH, Drapp R, Shaik S, Hu D, Lester C, Eguren M, Malumbres M, Glimcher LH, Wei W. Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. Molecular Cell. 44: 721-33. PMID 22152476 DOI: 10.1016/J.Molcel.2011.09.024  1
2011 Hetz C, Martinon F, Rodriguez D, Glimcher LH. The unfolded protein response: integrating stress signals through the stress sensor IRE1α. Physiological Reviews. 91: 1219-43. PMID 22013210 DOI: 10.1152/Physrev.00001.2011  1
2011 Zou W, Greenblatt MB, Shim JH, Kant S, Zhai B, Lotinun S, Brady N, Hu DZ, Gygi SP, Baron R, Davis RJ, Jones D, Glimcher LH. MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice. The Journal of Clinical Investigation. 121: 4383-92. PMID 21965325 DOI: 10.1172/Jci59041  1
2011 Jones D, Glimcher LH, Aliprantis AO. Osteoimmunology at the nexus of arthritis, osteoporosis, cancer, and infection. The Journal of Clinical Investigation. 121: 2534-42. PMID 21737885 DOI: 10.1172/Jci46262  1
2011 Hess DA, Humphrey SE, Ishibashi J, Damsz B, Lee AH, Glimcher LH, Konieczny SF. Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice. Gastroenterology. 141: 1463-72. PMID 21704586 DOI: 10.1053/J.Gastro.2011.06.045  1
2011 Lazarevic V, Glimcher LH. T-bet in disease. Nature Immunology. 12: 597-606. PMID 21685955 DOI: 10.1038/Ni.2059  1
2011 Lee AH, Heidtman K, Hotamisligil GS, Glimcher LH. Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion. Proceedings of the National Academy of Sciences of the United States of America. 108: 8885-90. PMID 21555585 DOI: 10.1073/Pnas.1105564108  1
2011 Ermann J, Garrett WS, Kuchroo J, Rourida K, Glickman JN, Bleich A, Glimcher LH. Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus. Proceedings of the National Academy of Sciences of the United States of America. 108: 7137-41. PMID 21482794 DOI: 10.1073/Pnas.1104234108  1
2011 Staton TL, Lazarevic V, Jones DC, Lanser AJ, Takagi T, Ishii S, Glimcher LH. Dampening of death pathways by schnurri-2 is essential for T-cell development. Nature. 472: 105-9. PMID 21475200 DOI: 10.1038/Nature09848  1
2011 Hetz C, Glimcher LH. Protein homeostasis networks in physiology and disease. Current Opinion in Cell Biology. 23: 123-5. PMID 21306885 DOI: 10.1016/J.Ceb.2011.01.004  1
2011 Matus S, Glimcher LH, Hetz C. Protein folding stress in neurodegenerative diseases: a glimpse into the ER. Current Opinion in Cell Biology. 23: 239-52. PMID 21288706 DOI: 10.1016/J.Ceb.2011.01.003  1
2011 Glimcher LH, Martinon F, Modlin RL. Editorial overview. Current Opinion in Immunology. 23: 1-2. PMID 21185707 DOI: 10.1016/j.coi.2010.12.001  1
2011 Lazarevic V, Chen X, Shim JH, Hwang ES, Jang E, Bolm AN, Oukka M, Kuchroo VK, Glimcher LH. T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt. Nature Immunology. 12: 96-104. PMID 21151104 DOI: 10.1038/Ni.1969  1
2011 Martinon F, Glimcher LH. Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum. Current Opinion in Immunology. 23: 35-40. PMID 21094031 DOI: 10.1016/J.Coi.2010.10.016  1
2011 Glimcher LH. A delicate balance: Science, medicine, and motherhood Medicine Science and Dreams: the Making of Physician-Scientists. 45-57. DOI: 10.1007/978-90-481-9538-1_4  1
2010 Veiga P, Gallini CA, Beal C, Michaud M, Delaney ML, DuBois A, Khlebnikov A, van Hylckama Vlieg JE, Punit S, Glickman JN, Onderdonk A, Glimcher LH, Garrett WS. Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes. Proceedings of the National Academy of Sciences of the United States of America. 107: 18132-7. PMID 20921388 DOI: 10.1073/Pnas.1011737107  1
2010 Schramek D, Leibbrandt A, Sigl V, Kenner L, Pospisilik JA, Lee HJ, Hanada R, Joshi PA, Aliprantis A, Glimcher L, Pasparakis M, Khokha R, Ormandy CJ, Widschwendter M, Schett G, et al. Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. Nature. 468: 98-102. PMID 20881962 DOI: 10.1038/Nature09387  1
2010 Garrett WS, Gallini CA, Yatsunenko T, Michaud M, DuBois A, Delaney ML, Punit S, Karlsson M, Bry L, Glickman JN, Gordon JI, Onderdonk AB, Glimcher LH. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host & Microbe. 8: 292-300. PMID 20833380 DOI: 10.1016/J.Chom.2010.08.004  1
2010 Huh WJ, Esen E, Geahlen JH, Bredemeyer AJ, Lee AH, Shi G, Konieczny SF, Glimcher LH, Mills JC. XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum. Gastroenterology. 139: 2038-49. PMID 20816838 DOI: 10.1053/J.Gastro.2010.08.050  1
2010 Collins PL, Chang S, Henderson M, Soutto M, Davis GM, McLoed AG, Townsend MJ, Glimcher LH, Mortlock DP, Aune TM. Distal regions of the human IFNG locus direct cell type-specific expression. Journal of Immunology (Baltimore, Md. : 1950). 185: 1492-501. PMID 20574006 DOI: 10.4049/Jimmunol.1000124  1
2010 Greenblatt MB, Shim JH, Zou W, Sitara D, Schweitzer M, Hu D, Lotinun S, Sano Y, Baron R, Park JM, Arthur S, Xie M, Schneider MD, Zhai B, Gygi S, ... ... Glimcher LH, et al. The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. The Journal of Clinical Investigation. 120: 2457-73. PMID 20551513 DOI: 10.1172/Jci42285  1
2010 Greenblatt MB, Aliprantis A, Hu B, Glimcher LH. Calcineurin regulates innate antifungal immunity in neutrophils. The Journal of Experimental Medicine. 207: 923-31. PMID 20421389 DOI: 10.1084/Jem.20092531  1
2010 Jones DC, Schweitzer MN, Wein M, Sigrist K, Takagi T, Ishii S, Glimcher LH. Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3. Proceedings of the National Academy of Sciences of the United States of America. 107: 8254-8. PMID 20404140 DOI: 10.1073/Pnas.1003727107  1
2010 Greenblatt MB, Shim JH, Glimcher LH. TAK1 mediates BMP signaling in cartilage. Annals of the New York Academy of Sciences. 1192: 385-90. PMID 20392264 DOI: 10.1111/J.1749-6632.2009.05222.X  1
2010 Martinon F, Chen X, Lee AH, Glimcher LH. TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nature Immunology. 11: 411-8. PMID 20351694 DOI: 10.1038/Ni.1857  1
2010 Garrett WS, Gordon JI, Glimcher LH. Homeostasis and inflammation in the intestine. Cell. 140: 859-70. PMID 20303876 DOI: 10.1016/J.Cell.2010.01.023  1
2010 Riol-Blanco L, Lazarevic V, Awasthi A, Mitsdoerffer M, Wilson BS, Croxford A, Waisman A, Kuchroo VK, Glimcher LH, Oukka M. IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections. Journal of Immunology (Baltimore, Md. : 1950). 184: 1710-20. PMID 20083652 DOI: 10.4049/Jimmunol.0902796  1
2010 Anderson AC, Lord GM, Dardalhon V, Lee DH, Sabatos-Peyton CA, Glimcher LH, Kuchroo VK. T-bet, a Th1 transcription factor regulates the expression of Tim-3. European Journal of Immunology. 40: 859-66. PMID 20049876 DOI: 10.1002/Eji.200939842  1
2010 Glimcher LH. XBP1: The last two decades Annals of the Rheumatic Diseases. 69. PMID 19995749 DOI: 10.1136/Ard.2009.119388  1
2010 Jones DC, Glimcher LH. Regulation of bone formation and immune cell development by Schnurri proteins. Advances in Experimental Medicine and Biology. 658: 117-22. PMID 19950022 DOI: 10.1007/978-1-4419-1050-9_13  1
2010 Aliprantis AO, Glimcher LH. NFATc1 in inflammatory and musculoskeletal conditions. Advances in Experimental Medicine and Biology. 658: 69-75. PMID 19950017 DOI: 10.1007/978-1-4419-1050-9_8  1
2009 Glimcher LH. Reflections on health care. The Journal of Clinical Investigation. 119: 2858-9. PMID 20069716 DOI: 10.1172/Jci40996  1
2009 Matus S, Nassif M, Glimcher LH, Hetz C. XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy. Autophagy. 5: 1226-8. PMID 19855189 DOI: 10.4161/Auto.5.8.10247  1
2009 Jenner RG, Townsend MJ, Jackson I, Sun K, Bouwman RD, Young RA, Glimcher LH, Lord GM. The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. Proceedings of the National Academy of Sciences of the United States of America. 106: 17876-81. PMID 19805038 DOI: 10.1073/Pnas.0909357106  1
2009 Hetz C, Thielen P, Matus S, Nassif M, Court F, Kiffin R, Martinez G, Cuervo AM, Brown RH, Glimcher LH. XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes & Development. 23: 2294-306. PMID 19762508 DOI: 10.1101/Gad.1830709  1
2009 Glimcher LH, Lee AH. From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis. Annals of the New York Academy of Sciences. 1173: E2-9. PMID 19751410 DOI: 10.1111/J.1749-6632.2009.04956.X  1
2009 Hetz C, Glimcher LH. Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome. Molecular Cell. 35: 551-61. PMID 19748352 DOI: 10.1016/J.Molcel.2009.08.021  1
2009 Garrett WS, Punit S, Gallini CA, Michaud M, Zhang D, Sigrist KS, Lord GM, Glickman JN, Glimcher LH. Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells. Cancer Cell. 16: 208-19. PMID 19732721 DOI: 10.1016/J.Ccr.2009.07.015  1
2009 Garrett WS, Glimcher LH. T-bet-/- RAG2-/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships. Cytokine. 48: 144-7. PMID 19666230 DOI: 10.1016/J.Cyto.2009.07.007  1
2009 Shim JH, Greenblatt MB, Xie M, Schneider MD, Zou W, Zhai B, Gygi S, Glimcher LH. TAK1 is an essential regulator of BMP signalling in cartilage. The Embo Journal. 28: 2028-41. PMID 19536134 DOI: 10.1038/Emboj.2009.162  1
2009 Esensten JH, Lee MR, Glimcher LH, Bluestone JA. T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function. Journal of Immunology (Baltimore, Md. : 1950). 183: 75-82. PMID 19535634 DOI: 10.4049/Jimmunol.0804154  1
2009 Yuan X, Ansari MJ, D'Addio F, Paez-Cortez J, Schmitt I, Donnarumma M, Boenisch O, Zhao X, Popoola J, Clarkson MR, Yagita H, Akiba H, Freeman GJ, Iacomini J, Turka LA, ... Glimcher LH, et al. Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 10734-9. PMID 19528638 DOI: 10.1073/Pnas.0812538106  1
2009 Lee AH, Glimcher LH. Intersection of the unfolded protein response and hepatic lipid metabolism. Cellular and Molecular Life Sciences : Cmls. 66: 2835-50. PMID 19468685 DOI: 10.1007/S00018-009-0049-8  1
2009 Glimcher LH, Lieberman J. Harvard's women four years later. Nature Immunology. 10: 559-61. PMID 19448653 DOI: 10.1038/Ni0609-559  1
2009 Maldonado RA, Soriano MA, Perdomo LC, Sigrist K, Irvine DJ, Decker T, Glimcher LH. Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse. The Journal of Experimental Medicine. 206: 877-92. PMID 19349465 DOI: 10.1084/Jem.20082900  1
2009 Lisbona F, Rojas-Rivera D, Thielen P, Zamorano S, Todd D, Martinon F, Glavic A, Kress C, Lin JH, Walter P, Reed JC, Glimcher LH, Hetz C. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Molecular Cell. 33: 679-91. PMID 19328063 DOI: 10.1016/J.Molcel.2009.02.017  1
2009 Lazarevic V, Zullo AJ, Schweitzer MN, Staton TL, Gallo EM, Crabtree GR, Glimcher LH. The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells. Nature Immunology. 10: 306-13. PMID 19169262 DOI: 10.1038/Ni.1696  1
2009 Park JW, Min HJ, Sohn JH, Kim JY, Hong JH, Sigrist KS, Glimcher LH, Hwang ES. Restoration of T-box-containing protein expressed in T cells protects against allergen-induced asthma. The Journal of Allergy and Clinical Immunology. 123: 479-85. PMID 19081613 DOI: 10.1016/J.Jaci.2008.10.035  1
2009 Glimcher LH. Foreword Protein Misfolding Disorders: a Trip Into the Er. DOI: 10.2174/97816080501301090101000i  1
2008 Wu J, Glimcher LH, Aliprantis AO. HCO3-/Cl- anion exchanger SLC4A2 is required for proper osteoclast differentiation and function. Proceedings of the National Academy of Sciences of the United States of America. 105: 16934-9. PMID 18971331 DOI: 10.1073/Pnas.0808763105  1
2008 Aliprantis AO, Ueki Y, Sulyanto R, Park A, Sigrist KS, Sharma SM, Ostrowski MC, Olsen BR, Glimcher LH. NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. The Journal of Clinical Investigation. 118: 3775-89. PMID 18846253 DOI: 10.1172/Jci35711  1
2008 Kaser A, Lee AH, Franke A, Glickman JN, Zeissig S, Tilg H, Nieuwenhuis EE, Higgins DE, Schreiber S, Glimcher LH, Blumberg RS. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell. 134: 743-56. PMID 18775308 DOI: 10.1016/J.Cell.2008.07.021  1
2008 Todd DJ, Lee AH, Glimcher LH. The endoplasmic reticulum stress response in immunity and autoimmunity. Nature Reviews. Immunology. 8: 663-74. PMID 18670423 DOI: 10.1038/Nri2359  1
2008 Lee AH, Scapa EF, Cohen DE, Glimcher LH. Regulation of hepatic lipogenesis by the transcription factor XBP1. Science (New York, N.Y.). 320: 1492-6. PMID 18556558 DOI: 10.1126/Science.1158042  1
2008 Werneck MB, Lugo-Villarino G, Hwang ES, Cantor H, Glimcher LH. T-bet plays a key role in NK-mediated control of melanoma metastatic disease. Journal of Immunology (Baltimore, Md. : 1950). 180: 8004-10. PMID 18523263 DOI: 10.4049/Jimmunol.180.12.8004  1
2008 Wein MN, Jones DC, Glimcher LH. Lentivirus delivery of shRNA constructs into osteoblasts. Methods in Molecular Biology (Clifton, N.J.). 455: 149-55. PMID 18463817 DOI: 10.1007/978-1-59745-104-8_11  1
2008 Horsley V, Aliprantis AO, Polak L, Glimcher LH, Fuchs E. NFATc1 balances quiescence and proliferation of skin stem cells. Cell. 132: 299-310. PMID 18243104 DOI: 10.1016/J.Cell.2007.11.047  1
2008 Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, ... ... Glimcher LH, et al. Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. The Journal of Clinical Investigation. 118: 491-504. PMID 18219387 DOI: 10.1172/Jci33102  1
2008 Hetz C, Lee AH, Gonzalez-Romero D, Thielen P, Castilla J, Soto C, Glimcher LH. Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 757-62. PMID 18178615 DOI: 10.1073/Pnas.0711094105  1
2008 Rengarajan J, Murphy E, Park A, Krone CL, Hett EC, Bloom BR, Glimcher LH, Rubin EJ. Mycobacterium tuberculosis Rv2224c modulates innate immune responses. Proceedings of the National Academy of Sciences of the United States of America. 105: 264-9. PMID 18172199 DOI: 10.1073/Pnas.0710601105  1
2008 Hetz C, Glimcher LH. XBP-1 and the UPRosome: Mastering secretory cell function Current Immunology Reviews. 4: 1-10. DOI: 10.2174/157339508783597280  1
2007 Glimcher LH, Jones DC, Wein MN. Control of postnatal bone mass by the zinc finger adapter protein Schnurri-3. Annals of the New York Academy of Sciences. 1116: 174-81. PMID 18083927 DOI: 10.1196/Annals.1402.044  1
2007 Jones DC, Wein MN, Glimcher LH. Schnurri-3: a key regulator of postnatal skeletal remodeling. Advances in Experimental Medicine and Biology. 602: 1-13. PMID 17966382 DOI: 10.1007/978-0-387-72009-8_1  1
2007 Jones DC, Wein MN, Glimcher LH. Schnurri-3 is an essential regulator of osteoblast function and adult bone mass. Annals of the Rheumatic Diseases. 66: iii49-51. PMID 17934096 DOI: 10.1136/Ard.2007.078352  1
2007 Garrett WS, Lord GM, Punit S, Lugo-Villarino G, Mazmanian SK, Ito S, Glickman JN, Glimcher LH. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell. 131: 33-45. PMID 17923086 DOI: 10.1016/J.Cell.2007.08.017  1
2007 Iwakoshi NN, Pypaert M, Glimcher LH. The transcription factor XBP-1 is essential for the development and survival of dendritic cells. The Journal of Experimental Medicine. 204: 2267-75. PMID 17875675 DOI: 10.1084/Jem.20070525  1
2007 Hetz C, Thielen P, Fisher J, Pasinelli P, Brown RH, Korsmeyer S, Glimcher L. The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis Cell Death and Differentiation. 14: 1386-1389. PMID 17510659 DOI: 10.1038/Sj.Cdd.4402166  1
2007 Erlebacher A, Vencato D, Price KA, Zhang D, Glimcher LH. Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus. The Journal of Clinical Investigation. 117: 1399-411. PMID 17446933 DOI: 10.1172/Jci28214  1
2007 Glimcher LH. Trawling for treasure: tales of T-bet. Nature Immunology. 8: 448-50. PMID 17440449 DOI: 10.1038/Ni0507-448  1
2007 Aliprantis AO, Wang J, Fathman JW, Lemaire R, Dorfman DM, Lafyatis R, Glimcher LH. Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13. Proceedings of the National Academy of Sciences of the United States of America. 104: 2827-30. PMID 17307869 DOI: 10.1073/Pnas.0700021104  1
2007 Alcaide P, Jones TG, Lord GM, Glimcher LH, Hallgren J, Arinobu Y, Akashi K, Paterson AM, Gurish MA, Luscinskas FW. Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue. The Journal of Experimental Medicine. 204: 431-9. PMID 17296784 DOI: 10.1084/Jem.20060626  1
2006 Taqueti VR, Grabie N, Colvin R, Pang H, Jarolim P, Luster AD, Glimcher LH, Lichtman AH. T-bet controls pathogenicity of CTLs in the heart by separable effects on migration and effector activity. Journal of Immunology (Baltimore, Md. : 1950). 177: 5890-901. PMID 17056513 DOI: 10.4049/Jimmunol.177.9.5890  1
2006 Martinon F, Glimcher LH. Gout: new insights into an old disease. The Journal of Clinical Investigation. 116: 2073-5. PMID 16886051 DOI: 10.1172/Jci29404  1
2006 Rosas LE, Snider HM, Barbi J, Satoskar AA, Lugo-Villarino G, Keiser T, Papenfuss T, Durbin JE, Radzioch D, Glimcher LH, Satoskar AR. Cutting edge: STAT1 and T-bet play distinct roles in determining outcome of visceral leishmaniasis caused by Leishmania donovani. Journal of Immunology (Baltimore, Md. : 1950). 177: 22-5. PMID 16785492 DOI: 10.4049/Jimmunol.177.1.22  1
2006 Jones DC, Wein MN, Oukka M, Hofstaetter JG, Glimcher MJ, Glimcher LH. Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. Science (New York, N.Y.). 312: 1223-7. PMID 16728642 DOI: 10.1126/Science.1126313  1
2006 Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schrinzel A, Glimcher LH, Korsmeyer SJ. Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1α Science. 312: 572-576. PMID 16645094 DOI: 10.1126/Science.1123480  1
2006 Wang J, Fathman JW, Lugo-Villarino G, Scimone L, von Andrian U, Dorfman DM, Glimcher LH. Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells. The Journal of Clinical Investigation. 116: 414-21. PMID 16410834 DOI: 10.1172/Jci26631  1
2006 Tirosh B, Iwakoshi NN, Glimcher LH, Ploegh HL. Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response Journal of Biological Chemistry. 281: 5852-5860. PMID 16332684 DOI: 10.1074/Jbc.M509061200  1
2006 Raby BA, Hwang ES, Van Steen K, Tantisira K, Peng S, Litonjua A, Lazarus R, Giallourakis C, Rioux JD, Sparrow D, Silverman EK, Glimcher LH, Weiss ST. T-bet polymorphisms are associated with asthma and airway hyperresponsiveness. American Journal of Respiratory and Critical Care Medicine. 173: 64-70. PMID 16179640 DOI: 10.1164/Rccm.200503-505Oc  1
2005 Lee AH, Chu GC, Iwakoshi NN, Glimcher LH. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. The Embo Journal. 24: 4368-80. PMID 16362047 DOI: 10.1038/Sj.Emboj.7600903  1
2005 Wein MN, Jones DC, Glimcher LH. Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity. Immunological Reviews. 208: 66-79. PMID 16313341 DOI: 10.1111/J.0105-2896.2005.00322.X  1
2005 Eun SH, Hong JH, Glimcher LH. IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508 Journal of Experimental Medicine. 202: 1289-1300. PMID 16275766 DOI: 10.1084/Jem.20051044  1
2005 Ravindran R, Foley J, Stoklasek T, Glimcher LH, McSorley SJ. Expression of T-bet by CD4 T cells is essential for resistance to Salmonella infection. Journal of Immunology (Baltimore, Md. : 1950). 175: 4603-10. PMID 16177105 DOI: 10.4049/Jimmunol.175.7.4603  1
2005 Sullivan BM, Jobe O, Lazarevic V, Vasquez K, Bronson R, Glimcher LH, Kramnik I. Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production. Journal of Immunology (Baltimore, Md. : 1950). 175: 4593-602. PMID 16177104 DOI: 10.4049/Jimmunol.175.7.4593  1
2005 Lugo-Villarino G, Ito S, Klinman DM, Glimcher LH. The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 13248-53. PMID 16135562 DOI: 10.1073/Pnas.0506638102  1
2005 Tirosh B, Iwakoshi NN, Glimcher LH, Ploegh HL. XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells Journal of Experimental Medicine. 202: 505-516. PMID 16103408 DOI: 10.1084/Jem.20050575  1
2005 Lord GM, Rao RM, Choe H, Sullivan BM, Lichtman AH, Luscinskas FW, Glimcher LH. T-bet is required for optimal proinflammatory CD4+ T-cell trafficking. Blood. 106: 3432-9. PMID 16014561 DOI: 10.1182/Blood-2005-04-1393  1
2005 Dorfman DM, Hwang ES, Shahsafaei A, Glimcher LH. T-bet, a T cell-associated transcription factor, is expressed in Hodgkin's lymphoma Human Pathology. 36: 10-15. PMID 15712176 DOI: 10.1016/J.Humpath.2004.10.006  1
2005 Tirosh B, Iwakoshi NN, Lilley BN, Lee AH, Glimcher LH, Ploegh HL. Human cytomegalovirus protein US11 provokes an unfolded protein response that may facilitate the degradation of class I major histocompatibility complex products. Journal of Virology. 79: 2768-79. PMID 15708995 DOI: 10.1128/Jvi.79.5.2768-2779.2005  1
2005 Buono C, Binder CJ, Stavrakis G, Witztum JL, Glimcher LH, Lichtman AH. T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses. Proceedings of the National Academy of Sciences of the United States of America. 102: 1596-601. PMID 15665085 DOI: 10.1073/Pnas.0409015102  1
2005 Hwang ES, Szabo SJ, Schwartzberg PL, Glimcher LH. T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science (New York, N.Y.). 307: 430-3. PMID 15662016 DOI: 10.1126/Science.1103336  1
2004 Mowen KA, Glimcher LH. Signaling pathways in Th2 development. Immunological Reviews. 202: 203-22. PMID 15546395 DOI: 10.1111/J.0105-2896.2004.00209.X  1
2004 Glimcher LH, Townsend MJ, Sullivan BM, Lord GM. Recent developments in the transcriptional regulation of cytolytic effector cells Nature Reviews Immunology. 4: 900-911. PMID 15516969 DOI: 10.1038/Nri1490  1
2004 Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Görgün C, Glimcher LH, Hotamisligil GS. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science (New York, N.Y.). 306: 457-61. PMID 15486293 DOI: 10.1126/Science.1103160  1
2004 Erlebacher A, Price KA, Glimcher LH. Maintenance of mouse trophoblast stem cell proliferation by TGF-β/activin Developmental Biology. 275: 158-169. PMID 15464579 DOI: 10.1016/J.Ydbio.2004.07.032  1
2004 Maldonade RA, Irvine DJ, Schreiber R, Glimcher LH. A role for the immunological synapse in lineage commitment of CD4 lymphocytes Nature. 431: 527-532. PMID 15386021 DOI: 10.1038/Nature02916  1
2004 Shaffer AL, Shapiro-Shelef M, Iwakoshi NN, Lee AH, Qian SB, Zhao H, Yu X, Yang L, Tan BK, Rosenwald A, Hurt EM, Petroulakis E, Sonenberg N, Yewdell JW, Calame K, ... Glimcher LH, et al. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity. 21: 81-93. PMID 15345222 DOI: 10.1016/J.Immuni.2004.06.010  1
2004 Mowen KA, Schurter BT, Fathman JW, David M, Glimcher LH. Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes. Molecular Cell. 15: 559-71. PMID 15327772 DOI: 10.1016/J.Molcel.2004.06.042  1
2004 Dorfman DM, Hwang ES, Shahsafaei A, Glimcher LH. T-bet, a T-cell-associated transcription factor, is expressed in a subset of B-cell lymphoproliferative disorders American Journal of Clinical Pathology. 122: 292-297. PMID 15323146 DOI: 10.1309/Aqq2Dvm75Dvy0Pwp  1
2004 Glimcher LH. How we can help the next generation of scientists: Introducing the "hands-on" primary caregiver's support program Journal of Immunology. 173: 2891-2892. PMID 15322140 DOI: 10.4049/Jimmunol.173.5.2891  1
2004 Bettelli E, Sullivan B, Szabo SJ, Sobel RA, Glimcher LH, Kuchroo VK. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 200: 79-87. PMID 15238607 DOI: 10.1084/Jem.20031819  1
2004 Erlebacher A, Zhang D, Parlow AF, Glimcher LH. Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system Journal of Clinical Investigation. 114: 39-48. PMID 15232610 DOI: 10.1172/Jci20645  1
2004 Juedes AE, Rodrigo E, Togher L, Glimcher LH, von Herrath MG. T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes. The Journal of Experimental Medicine. 199: 1153-62. PMID 15096540 DOI: 10.1084/Jem.20031873  1
2004 Townsend MJ, Weinmann AS, Matsuda JL, Salomon R, Farnham PJ, Biron CA, Gapin L, Glimcher LH. T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity. 20: 477-94. PMID 15084276 DOI: 10.1016/S1074-7613(04)00076-7  1
2004 Gerth AJ, Lin L, Neurath MF, Glimcher LH, Peng SL. An Innate Cell-Mediated, Murine Ulcerative Colitis-like Syndrome in the Absence of Nuclear Factor of Activated T Cells Gastroenterology. 126: 1115-1121. PMID 15057750 DOI: 10.1053/J.Gastro.2004.01.013  1
2004 Oukka M, Wein MN, Glimcher LH. Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells. The Journal of Experimental Medicine. 199: 15-24. PMID 14707112 DOI: 10.1084/Jem.20030421  1
2003 Pai SY, Truitt ML, Ting CN, Leiden JM, Glimcher LH, Ho IC. Critical roles for transcription factor GATA-3 in thymocyte development. Immunity. 19: 863-75. PMID 14670303 DOI: 10.1016/S1074-7613(03)00328-5  1
2003 Iwakoshi NN, Lee AH, Glimcher LH. It's a good year for Blimp-1 (and plasma cells) Immunity. 19: 466-468. PMID 14563311 DOI: 10.1016/S1074-7613(03)00274-7  1
2003 Lee AH, Iwakoshi NN, Glimcher LH. XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response Molecular and Cellular Biology. 23: 7448-7459. PMID 14559994 DOI: 10.1128/Mcb.23.21.7448-7459.2003  1
2003 MacLean HE, Kim JI, Glimcher MJ, Wang J, Kronenberg HM, Glimcher LH. Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development Developmental Biology. 262: 51-63. PMID 14512017 DOI: 10.1016/S0012-1606(03)00324-5  1
2003 Lee AH, Iwakoshi NN, Anderson KC, Glimcher LH. Proteasome inhibitors disrupt the unfolded protein response in myeloma cells Proceedings of the National Academy of Sciences of the United States of America. 100: 9946-9951. PMID 12902539 DOI: 10.1073/Pnas.1334037100  1
2003 Iwakoshi NN, Lee AH, Glimcher LH. The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response Immunological Reviews. 194: 29-38. PMID 12846805 DOI: 10.1034/J.1600-065X.2003.00057.X  1
2003 Lugo-Villarino G, Maldonado-Lopez R, Possemato R, Penaranda C, Glimcher LH. T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 7749-54. PMID 12802010 DOI: 10.1073/Pnas.1332767100  1
2003 Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, Glimcher LH. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-I Nature Immunology. 4: 321-329. PMID 12612580 DOI: 10.1038/Ni907  1
2003 Szabo SJ, Sullivan BM, Peng SL, Glimcher LH. Molecular mechanisms regulating Th1 immune responses Annual Review of Immunology. 21: 713-758. PMID 12500979 DOI: 10.1146/Annurev.Immunol.21.120601.140942  1
2002 Erlebacher A, Lukens AK, Glimcher LH. Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo. Proceedings of the National Academy of Sciences of the United States of America. 99: 16940-5. PMID 12486249 DOI: 10.1073/Pnas.222652199  1
2002 Avni O, Lee D, Macian F, Szabo SJ, Glimcher LH, Rao A. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nature Immunology. 3: 643-51. PMID 12055628 DOI: 10.1038/Ni808  1
2002 Neurath MF, Finotto S, Glimcher LH. The role of TH1/TH2 polarization in mucosal immunity Nature Medicine. 8: 567-573. PMID 12042806 DOI: 10.1038/Nm0602-567  1
2002 Neurath MF, Weigmann B, Finotto S, Glickman J, Nieuwenhuis E, Iijima H, Mizoguchi A, Mizoguchi E, Mudter J, Galle PR, Bhan A, Autschbach F, Sullivan BM, Szabo SJ, Glimcher LH, et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease Journal of Experimental Medicine. 195: 1129-1143. PMID 11994418 DOI: 10.1084/Jem.20011956  1
2002 Ho IC, Glimcher LH. Transcription: Tantalizing times for T cells Cell. 109. PMID 11983157 DOI: 10.1016/S0092-8674(02)00705-5  1
2002 Peng SL, Szabo SJ, Glimcher LH. T-bet regulates IgG class switching and pathogenic autoantibody production Proceedings of the National Academy of Sciences of the United States of America. 99: 5545-5550. PMID 11960012 DOI: 10.1073/Pnas.082114899  1
2002 Rengarajan J, Mowen KA, McBride KD, Smith ED, Singh H, Glimcher LH. Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. The Journal of Experimental Medicine. 195: 1003-12. PMID 11956291 DOI: 10.1084/Jem.20011128  1
2002 Oukka M, Kim ST, Lugo G, Sun J, Wu LC, Glimcher LH. A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2. Molecular Cell. 9: 121-31. PMID 11804591 DOI: 10.1016/S1097-2765(01)00434-8  1
2002 Szabo SJ, Sullivan BM, Stemmann C, Satoskar AR, Sleckman BP, Glimcher LH. Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science (New York, N.Y.). 295: 338-42. PMID 11786644 DOI: 10.1126/Science.1065543  0.44
2002 Finotto S, Neurath MF, Glickman JN, Qin S, Lehr HA, Green FH, Ackerman K, Haley K, Galle PR, Szabo SJ, Drazen JM, De Sanctis GT, Glimcher LH. Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science (New York, N.Y.). 295: 336-8. PMID 11786643 DOI: 10.1126/Science.1065544  0.44
2002 Rengarajan J, Tang B, Glimcher LH. NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells. Nature Immunology. 3: 48-54. PMID 11740499 DOI: 10.1038/Ni744  1
2001 Glimcher LH. Lineage commitment in lymphocytes: Controlling the immune response Journal of Clinical Investigation. 108. PMID 11669073  1
2001 Lieberson R, Mowen KA, McBride KD, Leautaud V, Zhang X, Suh WK, Wu L, Glimcher LH. Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45) Journal of Experimental Medicine. 194: 89-98. PMID 11435475 DOI: 10.1084/Jem.194.1.89  1
2001 Peng SL, Gerth AJ, Ranger AM, Glimcher LH. NFATc1 and NFATc2 together control both T and B cell activation and differentiation Immunity. 14: 13-20. PMID 11163226 DOI: 10.1016/S1074-7613(01)00085-1  1
2001 Reimold AM, Kim J, Finberg R, Glimcher LH. Decreased immediate inflammatory gene induction in activating transcription factor-2 mutant mice International Immunology. 13: 241-248. PMID 11157857 DOI: 10.1093/Intimm/13.2.241  1
2001 Pauza ME, Nguyen A, Wolfe T, Ho IC, Glimcher LH, Von Herrath M, Lo D. Variable effects of transgenic c-Maf on autoimmune diabetes Diabetes. 50: 39-46. PMID 11147792 DOI: 10.2337/Diabetes.50.1.39  1
2000 Rengarajan J, Szabo SJ, Glimcher LH. Transcriptional regulation of Th1/Th2 polarization. Immunology Today. 21: 479-83. PMID 11071525 DOI: 10.1016/S0167-5699(00)01712-6  1
2000 Tsai EY, Falvo JV, Tsytsykova AV, Barczak AK, Reimold AM, Glimcher LH, Fenton MJ, Gordon DC, Dunn IF, Goldfeld AE. A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo. Molecular and Cellular Biology. 20: 6084-94. PMID 10913190 DOI: 10.1128/Mcb.20.16.6084-6094.2000  1
2000 Glimcher LH, Murphy KM. Lineage commitment in the immune system: the T helper lymphocyte grows up. Genes & Development. 14: 1693-711. PMID 10898785 DOI: 10.1101/Gad.14.14.1693  1
2000 Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 100: 655-69. PMID 10761931 DOI: 10.1016/S0092-8674(00)80702-3  1
2000 Rengarajan J, Mittelstadt PR, Mages HW, Gerth AJ, Kroczek RA, Ashwell JD, Glimcher LH. Sequential involvement of NFAT and Egr transcription factors in FasL regulation. Immunity. 12: 293-300. PMID 10755616 DOI: 10.1016/S1074-7613(00)80182-X  1
2000 Reimold AM, Etkin A, Clauss I, Perkins A, Friend DS, Zhang J, Horton HF, Scott A, Orkin SH, Byrne MC, Grusby MJ, Glimcher LH. An essential role in liver development for transcription factor XBP-1. Genes & Development. 14: 152-7. PMID 10652269 DOI: 10.1101/Gad.14.2.152  1
2000 Ranger AM, Gerstenfeld LC, Wang J, Kon T, Bae H, Gravallese EM, Glimcher MJ, Glimcher LH. The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis Journal of Experimental Medicine. 191: 9-21. PMID 10620601 DOI: 10.1084/Jem.191.1.9  1
1999 Ho IC, Kim JI, Szabo SJ, Glimcher LH. Tissue-specific regulation of cytokine gene expression Cold Spring Harbor Symposia On Quantitative Biology. 64: 573-584. PMID 11232334 DOI: 10.1101/Sqb.1999.64.573  1
1999 de Bont ES, Reilly CR, Lo D, Glimcher LH, Laufer TM. A minimal level of MHC class II expression is sufficient to abrogate autoreactivity. International Immunology. 11: 1295-306. PMID 10421787 DOI: 10.1093/Intimm/11.8.1295  1
1999 Kim JI, Ho IC, Grusby MJ, Glimcher LH. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines Immunity. 10: 745-751. PMID 10403649 DOI: 10.1016/S1074-7613(00)80073-4  1
1999 Wen XY, Stewart AK, Sooknanan RR, Henderson G, Hawley T, Reimold AM, Glimcher LH, Baumann H, Malek LT, Hawley RG. Identification of c-myc promoter-binding protein and X-box binding protein 1 as interleukin-6 target genesin human multiple myeloma cells International Journal of Oncology. 15: 173-178. PMID 10375612 DOI: 10.3892/Ijo.15.1.173  1
1999 Laufer TM, Fan L, Glimcher LH. Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo Journal of Immunology. 162: 5078-5084. PMID 10227976  1
1999 Kim JI, Li T, Ho IC, Grusby MJ, Glimcher LH. Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development Proceedings of the National Academy of Sciences of the United States of America. 96: 3781-3785. PMID 10097114 DOI: 10.1073/Pnas.96.7.3781  1
1999 Ho IC, Kaplan MH, Jackson-Grusby L, Glimcher LH, Grusby MJ. Marking IL-4-producing cells by knock-in of the IL-4 gene. International Immunology. 11: 243-7. PMID 10069422 DOI: 10.1093/Intimm/11.2.243  1
1999 Glimcher LH, Singh H. Transcription factors in lymphocyte development - T and B cells get together Cell. 96: 13-23. PMID 9989493 DOI: 10.1016/S0092-8674(00)80955-1  1
1999 Laufer TM, Glimcher LH, Lo D. Using thymus anatomy to dissect T cell repertoire selection Seminars in Immunology. 11: 65-70. PMID 9950753 DOI: 10.1006/Smim.1998.9997  1
1998 Ranger AM, Oukka M, Rengarajan J, Glimcher LH. Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. Immunity. 9: 627-35. PMID 9846484 DOI: 10.1016/S1074-7613(00)80660-3  1
1998 Ho IC, Lo D, Glimcher LH. c-maf Promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms Journal of Experimental Medicine. 188: 1859-1866. PMID 9815263 DOI: 10.1084/Jem.188.10.1859  1
1998 Oukka M, Ho IC, de la Brousse FC, Hoey T, Grusby MJ, Glimcher LH. The transcription factor NFAT4 is involved in the generation and survival of T cells. Immunity. 9: 295-304. PMID 9768749 DOI: 10.1016/S1074-7613(00)80612-3  1
1998 Ranger AM, Grusby MJ, Hodge MR, Gravallese EM, de la Brousse FC, Hoey T, Mickanin C, Baldwin HS, Glimcher LH. The transcription factor NF-ATc is essential for cardiac valve formation. Nature. 392: 186-90. PMID 9515964 DOI: 10.1038/32426  1
1998 Ranger AM, Hodge MR, Gravallese EM, Oukka M, Davidson L, Alt FW, de la Brousse FC, Hoey T, Grusby M, Glimcher LH. Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc. Immunity. 8: 125-34. PMID 9462518 DOI: 10.1016/S1074-7613(00)80465-3  1
1998 Sabatine MS, Laufer T, Glimcher LH, Widmer M, Winn H, Auchincloss H. Delayed rejection of soluble tumor necrosis factor receptor-secreting tumor allografts Transplantation. 65: 113-120. PMID 9448155 DOI: 10.1097/00007890-199801150-00022  1
1997 Szabo SJ, Glimcher LH, Ho IC. Genes that regulate interleukin-4 expression in T cells Current Opinion in Immunology. 9: 776-781. PMID 9492977 DOI: 10.1016/S0952-7915(97)80177-X  1
1997 Douhan J, Lieberson R, Knoll JHM, Zhou H, Glimcher LH. An isotype-specific activator of major histocompatibility complex (MHC) class II genes that is independent of class II transactivator Journal of Experimental Medicine. 185: 1885-1895. PMID 9166418 DOI: 10.1084/Jem.185.11.1885  1
1997 Zhou H, Su HS, Zhang X, Douhan J, Glimcher LH. CIITA-Dependent and -Independent Class II MHC Expression Revealed by a Dominant Negative Mutant Journal of Immunology. 158: 4741-4749. PMID 9144488  1
1997 Lo D, Reilly CR, Burkly LC, DeKoning J, Laufer TM, Glimcher LH. Thymic stromal cell specialization and the T-cell receptor repertoire. Immunologic Research. 16: 3-14. PMID 9048205 DOI: 10.1007/Bf02786320  1
1996 Hodge MR, Chun HJ, Rengarajan J, Alt A, Lieberson R, Glimcher LH. NF-AT-Driven interleukin-4 transcription potentiated by NIP45. Science (New York, N.Y.). 274: 1903-5. PMID 8943202 DOI: 10.1126/Science.274.5294.1903  1
1996 Brown JA, Titus RG, Nabavi N, Glimcher LH. Blockade of CD86 ameliorates Leishmania major infection by down- regulating the Th2 response Journal of Infectious Diseases. 174: 1303-1308. PMID 8940222 DOI: 10.1093/Infdis/174.6.1303  1
1996 Ranger AM, Das MP, Kuchroo VK, Glimcher LH. B7-2 (CD86) is essential for the development of IL-4-producing T cells International Immunology. 8: 1549-1560. PMID 8921434 DOI: 10.1093/Intimm/8.10.1549  1
1996 Laufer TM, DeKoning J, Markowitz JS, Lo D, Glimcher LH. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex Nature. 383: 81-85. PMID 8779719 DOI: 10.1038/383081A0  1
1996 Ho IC, Hodge MR, Rooney JW, Glimcher LH. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4 Cell. 85: 973-983. PMID 8674125 DOI: 10.1016/S0092-8674(00)81299-4  1
1996 Douhan J, Brown JA, Gleit ZL, David CS, Glimcher LH. Regulation of the Eβ gene in vivo: Lessons from Eβd transgenic mice International Immunology. 8: 255-265. PMID 8671611 DOI: 10.1093/Intimm/8.2.255  1
1996 Tarleton RL, Grusby MJ, Postan M, Glimcher LH. Trypanosoma cruzi infection in MHC-deficient mice: Further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease International Immunology. 8: 13-22. PMID 8671585 DOI: 10.1093/Intimm/8.1.13  1
1996 Clauss IM, Chu M, Zhao JL, Glimcher LH. The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core Nucleic Acids Research. 24: 1855-1864. PMID 8657566 DOI: 10.1093/Nar/24.10.1855  1
1996 Zhao JL, Freeman GJ, Gray GS, Nadler LM, Glimcher LH. A cell type-specific enhancer in the human B7.1 gene regulated by NF-κB Journal of Experimental Medicine. 183: 777-789. PMID 8642282 DOI: 10.1084/Jem.183.3.777  1
1996 Douhan J, Hauber I, Eibl MM, Glimcher LH. Genetic evidence for a new type of major histocompatibility complex class II combined immunodeficiency characterized by a dyscoordinate regulation of HLA-D alpha and beta chains. The Journal of Experimental Medicine. 183: 1063-9. PMID 8642248 DOI: 10.1084/Jem.183.3.1063  1
1996 Steele DJ, Laufer TM, Smiley ST, Ando Y, Grusby MJ, Glimcher LH, Auchincloss H. Two levels of help for B cell alloantibody production. The Journal of Experimental Medicine. 183: 699-703. PMID 8627185 DOI: 10.1084/Jem.183.2.699  1
1996 Reimold AM, Ponath PD, Li YS, Hardy RR, David CS, Strominger JL, Glimcher LH. Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1 Journal of Experimental Medicine. 183: 393-401. PMID 8627152 DOI: 10.1084/Jem.183.2.393  1
1996 Hodge MR, Ranger AM, Charles de la Brousse F, Hoey T, Grusby MJ, Glimcher LH. Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice. Immunity. 4: 397-405. PMID 8612134 DOI: 10.1016/S1074-7613(00)80253-8  1
1996 Smiley ST, Rudensky AY, Glimcher LH, Grusby MJ. Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes. Proceedings of the National Academy of Sciences of the United States of America. 93: 241-4. PMID 8552613 DOI: 10.1073/Pnas.93.1.241  1
1996 Reimold AM, Grusby MJ, Kosaras B, Fries JW, Mori R, Maniwa S, Clauss IM, Collins T, Sidman RL, Glimcher MJ, Glimcher LH. Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice. Nature. 379: 262-5. PMID 8538792 DOI: 10.1038/379262A0  1
1995 Baskar S, Glimcher L, Nabavi N, Jones RT, Ostrand-Rosenberg S. Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice. The Journal of Experimental Medicine. 181: 619-29. PMID 7836917 DOI: 10.1084/Jem.181.2.619  1
1995 Hodge MR, Rooney JW, Glimcher LH. The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites that bind at least two distinct factors Journal of Immunology. 154: 6397-6405. PMID 7759876  1
1995 Chakkalath HR, Theodos CM, Markowitz JS, Grusby MJ, Glimcher LH, Titus RG. Class II major histocompatibility complex-deficient mice initially control an infection with leishmania major but succumb to the disease Journal of Infectious Diseases. 171: 1302-1308. PMID 7751707 DOI: 10.1093/Infdis/171.5.1302  1
1995 Zhou H, Glimcher LH. Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency Immunity. 2: 545-553. PMID 7749985 DOI: 10.1016/1074-7613(95)90034-9  1
1995 Rooney JW, Hoey T, Glimcher LH. Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene. Immunity. 2: 473-83. PMID 7749982 DOI: 10.1016/1074-7613(95)90028-4  1
1995 Grusby MJ, Glimcher LH. Immune responses in MHC class II-deficient mice Annual Review of Immunology. 13: 417-435. PMID 7612230 DOI: 10.1146/Annurev.Iy.13.040195.002221  1
1995 Rooney JW, Sun YL, Glimcher LH, Hoey T. Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation. Molecular and Cellular Biology. 15: 6299-310. PMID 7565783 DOI: 10.1128/Mcb.15.11.6299  1
1995 Smiley ST, Laufer TM, Lo D, Glimcher LH, Grusby MJ. Transgenic mice expressing MHC class II molecules with truncated A beta cytoplasmic domains reveal signaling-independent defects in antigen presentation. International Immunology. 7: 665-77. PMID 7547694 DOI: 10.1093/Intimm/7.4.665  1
1995 Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell. 80: 707-18. PMID 7534215 DOI: 10.1016/0092-8674(95)90349-6  1
1994 Rooney JW, Hodge MR, McCaffrey PG, Rao A, Glimcher LH. A common factor regulates both Th1- and Th2-specific cytokine gene expression Embo Journal. 13: 625-633. PMID 8313907 DOI: 10.1002/J.1460-2075.1994.Tb06300.X  1
1994 Lederer JA, Liou JS, Todd MD, Glimcher LH, Lichtman AH. Regulation of cytokine gene expression in T helper cell subsets. Journal of Immunology (Baltimore, Md. : 1950). 152: 77-86. PMID 8254209  1
1994 Ivashkiv LB, Ayres A, Glimcher LH. Inhibition of IFN-γ induction of class II MHC genes by cAMP and prostaglandins Immunopharmacology. 27: 67-77. PMID 8206755 DOI: 10.1016/0162-3109(94)90008-6  1
1994 Lee RS, Grusby MJ, Glimcher LH, Winn HJ, Auchincloss H. Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo Journal of Experimental Medicine. 179: 865-872. PMID 8113680 DOI: 10.1084/Jem.179.3.865  1
1994 Matsushima GK, Taniike M, Glimcher LH, Grusby MJ, Frelinger JA, Suzuki K, Ting JP. Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy. Cell. 78: 645-56. PMID 8069913 DOI: 10.1016/0092-8674(94)90529-0  1
1994 Darling JM, Glimcher LH, Shortkroff S, Albano B, Gravallese EM. Expression of metalloproteinases in pigmented villonodular synovitis. Human Pathology. 25: 825-30. PMID 8056425 DOI: 10.1016/0046-8177(94)90254-2  1
1994 Avery AC, Markowitz JS, Grusby MJ, Glimcher LH, Cantor H. Activation of T cells by superantigen in class II-negative mice Journal of Immunology. 153: 4853-4861. PMID 7963549  1
1994 Jevnikar AM, Grusby MJ, Glimcher LH. Prevention of nephritis in major histocompatibility complex class II-deficient MRL-1pr mice Journal of Experimental Medicine. 179: 1137-1143. PMID 7908320 DOI: 10.1084/Jem.179.4.1137  1
1994 Degermann S, Surh CD, Glimcher LH, Sprent J, Lo D. B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of Vβ5+ thymocytes Journal of Immunology. 152: 3254-3263. PMID 7511640  1
1993 Kara CJ, Glimcher LH. Developmental and Cytokine-Mediated Regulation of MHC Class II Gene Promoter Occupancy in Vivo Journal of Immunology. 150: 4934-4942. PMID 8496595  1
1993 Markowitz JS, Auchincloss H, Grusby MJ, Glimcher LH. Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice Proceedings of the National Academy of Sciences of the United States of America. 90: 2779-2783. PMID 8464889 DOI: 10.1073/Pnas.90.7.2779  1
1993 Lee R, Glimcher LH, Auchincloss H. Evidence that a 'four-cell cluster' may prime cytotoxic T-cells during graft rejection Transplantation Proceedings. 25: 847-849. PMID 8442245  1
1993 Jevnikar AM, Singer GG, Coffman T, Glimcher LH, Kelley VER. Renal tubular cell expression of MHC class II (I-Eb) is insufficient to initiate immune injury in a transgenic kidney transplant model Transplantation Proceedings. 25: 142-143. PMID 8438254  1
1993 Markowitz JS, Rogers PR, Grusby MJ, Parker DC, Glimcher LH. B lymphocyte development and activation independent of MHC class II expression Journal of Immunology. 150: 1223-1233. PMID 8432977  1
1993 Kara CJ, Glimcher LH. Promoter accessibility within the environment of the MHC is affected in class II-deficient combined immunodeficiency Embo Journal. 12: 187-193. PMID 8428578 DOI: 10.1002/J.1460-2075.1993.Tb05644.X  1
1993 Kara CJ, Glimcher LH. Three in vivo promoter phenotypes in MHC class II deficient combined immunodeficiency Immunogenetics. 37: 227-230. PMID 8420831 DOI: 10.1007/Bf00191890  1
1993 Reimold AM, Kara CJ, Rooney JW, Glimcher LH. Transforming growth factor β1 repression of the HLA-DRα gene is mediated by conserved proximal promoter elements Journal of Immunology. 151: 4173-4182. PMID 8409394  1
1993 Ponath PD, Fass D, Liou HC, Glimcher LH, Strominger JL. The regulatory gene, hXBP-1, and its target, HLA-DRA, utilize both common and distinct regulatory elements and protein complexes Journal of Biological Chemistry. 268: 17074-17082. PMID 8349596  1
1993 Baskar S, Nabavi N, Glimcher LH, Ostrand-Rosenberg S. Tumor cells expressing major histocompatibility complex class II and B7 activation molecules stimulate potent tumor-specific immunity Journal of Immunotherapy. 14: 209-215. PMID 8297902 DOI: 10.1097/00002371-199310000-00007  1
1993 Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules. The Journal of Experimental Medicine. 178: 1701-12. PMID 8228817 DOI: 10.1084/Jem.178.5.1701  1
1993 Mombaerts P, Mizoguchi E, Grusby MJ, Glimcher LH, Bhan AK, Tonegawa S. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell. 75: 274-82. PMID 8104709 DOI: 10.1016/0092-8674(93)80069-Q  1
1993 Crump AL, Grusby MJ, Glimcher LH, Cantor H. Thymocyte development in major histocompatibility complex-deficient mice: Evidence for stochastic commitment to the CD4 and CD8 lineages Proceedings of the National Academy of Sciences of the United States of America. 90: 10739-10743. PMID 7902569 DOI: 10.1073/Pnas.90.22.10739  1
1993 Clauss IM, Gravallese EM, Darling JM, Shapiro F, Glimcher MJ, Glimcher LH. In situ hybridization studies suggest a role for the basic region-leucine zipper protein hXBP-1 in exocrine gland and skeletal development during mouse embryogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 197: 146-56. PMID 7693055 DOI: 10.1002/Aja.1001970207  1
1993 Baskar S, Ostrand-Rosenberg S, Nabavi N, Nadler LM, Freeman GJ, Glimcher LH. Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules Proceedings of the National Academy of Sciences of the United States of America. 90: 5687-5690. PMID 7685909 DOI: 10.1073/Pnas.90.12.5687  1
1992 Ivashkiv LB, Fleming MD, Glimcher LH. Dominant negative mutants of transcription factor mXBP (CRE-BP1, ATF-2) The New Biologist. 4: 360-368. PMID 1622931  1
1992 Glimcher LH, Kara CJ. Sequences and factors: A guide to MHC class-II transcription Annual Review of Immunology. 10: 13-49. PMID 1590984 DOI: 10.1146/Annurev.Iy.10.040192.000305  1
1992 Hong SC, Chelouche A, Lin RH, Shaywitz D, Braunstein NS, Glimcher L, Janeway CA. An MHC interaction site maps to the amino-terminal half of the T cell receptor alpha chain variable domain. Cell. 69: 999-1009. PMID 1318787 DOI: 10.1016/0092-8674(92)90618-M  1
1992 Nabavi N, Freeman GJ, Gault A, Godfrey D, Nadler LM, Glimcher LH. Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression Nature. 360: 266-268. PMID 1279442 DOI: 10.1038/360266A0  1
1991 Catherine CJ, Glimcher LH. Regulation of MHC class 11 gene transcription Current Opinion in Immunology. 3: 16-21. PMID 2054109 DOI: 10.1016/0952-7915(91)90070-H  1
1991 Gravallese EM, Darling JM, Glimcher LH, Boothby M. Role of lipopolysaccharide and IL-4 in control of transcription of the class II A alpha gene. Journal of Immunology (Baltimore, Md. : 1950). 147: 2377-83. PMID 1918969  1
1991 Grusby MJ, Johnson RS, Papaioannou VE, Glimcher LH. Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice Science. 253: 1417-1420. PMID 1910207 DOI: 10.1126/Science.1910207  1
1991 Ono SJ, Liou HC, Davidon R, Strominger JL, Glimcher LH. Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos Proceedings of the National Academy of Sciences of the United States of America. 88: 4309-4312. PMID 1903538 DOI: 10.1073/Pnas.88.10.4309  1
1991 Finn PW, Kara CJ, Grusby MJ, Folsom V, Glimcher LH. Upstream elements of the MHC class II Eβ gene active in B cells Journal of Immunology. 146: 4011-4015. PMID 1903416  1
1991 Kara CJ, Glimcher LH. In vivo foot printing of MHC class II genes: Bare promoters in the bare lymphocyte syndrome Science. 252: 709-712. PMID 1902592 DOI: 10.1126/Science.1902592  1
1991 Ivashkiv LB, Glimcher LH. Repression of class II major histocompatibility complex genes by cyclic AMP is mediated by conserved promoter elements Journal of Experimental Medicine. 174: 1583-1592. PMID 1660527 DOI: 10.1084/Jem.174.6.1583  1
1991 Gravallese EM, Darling JM, Ladd AL, Katz JN, Glimcher LH. In situ hybridization studies of stromelysin and collagenase messenger RNA expression in rheumatoid synovium. Arthritis and Rheumatism. 34: 1076-84. PMID 1657007 DOI: 10.1002/Art.1780340903  1
1990 Grusby MJ, Mitchell SC, Nabavi N, Glimcher LH. Casein expression in cytotoxic T lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 87: 6897-6901. PMID 2395885 DOI: 10.1073/Pnas.87.17.6897  1
1990 Brown MA, Griffith IJ, Glimcher LH. Functional and molecular characterization of I-Aβk mutants is consistent with the predicted three dimensional structure of class II MHC molecules Molecular Immunology. 27: 645-650. PMID 2395436 DOI: 10.1016/0161-5890(90)90007-M  1
1990 Grusby MJ, Mitchell SC, Glimcher LH. Molecular cloning of mouse cathepsin D Nucleic Acids Research. 18: 4008. PMID 2374732 DOI: 10.1093/Nar/18.13.4008  1
1990 Finn PW, Van TT, Accolla RS, Glimcher LH. Loss of a DNA-protein complex correlates with extinguished major histocompatibility complex class II expression in a human B cell. The Journal of Experimental Medicine. 171: 2159-64. PMID 2351936 DOI: 10.1084/Jem.171.6.2159  1
1990 Liou HC, Boothby MR, Finn PW, Davidon R, Nabavi N, Zeleznik-Le NJ, Ting JP, Glimcher LH. A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter. Science (New York, N.Y.). 247: 1581-4. PMID 2321018 DOI: 10.1126/Science.2321018  1
1990 Kara CJ, Liou HC, Ivashkiv LB, Glimcher LH. A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain Molecular and Cellular Biology. 10: 1347-1357. PMID 2320002 DOI: 10.1128/Mcb.10.4.1347  1
1990 Grusby MJ, Nabavi N, Wong H, Dick RF, Bluestone JA, Schotz MC, Glimcher LH. Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase Cell. 60: 451-459. PMID 2302735 DOI: 10.1016/0092-8674(90)90596-7  1
1990 Scholl PR, Sekaly RP, Diez A, Glimcher LH, Geha RS. Binding of toxic shock syndrome toxin-1 to murine major histocompatibility complex class II molecules European Journal of Immunology. 20: 1911-1916. PMID 2209697 DOI: 10.1002/Eji.1830200907  1
1990 Boothby M, Liou HC, Finn PW, Gravallese E, Glimcher LH. Control of transcription at the murine Aα locus Immunologic Research. 9: 77-92. PMID 2189937 DOI: 10.1007/Bf02918199  1
1990 Nabavi N, Grusby MJ, Finn PW, Wolgemuth DJ, Glimcher LH. Identification of an Il-4-Inducible Gene Expressed in Differentiating Lymphocytes and Male Germ Cells Developmental Immunology. 1: 19-30. PMID 2136202 DOI: 10.1155/1990/94056  1
1990 Finn PW, Kara CJ, Douhan J, Van TT, Folsom V, Glimcher LH. Interferon γ regulates binding of two nuclear protein complexes in a macrophage cell line Proceedings of the National Academy of Sciences of the United States of America. 87: 914-918. PMID 2105504 DOI: 10.1073/Pnas.87.3.914  1
1990 Fontaine B, Hanson MP, Liou HC, Glimcher LH, Rouleau GA, Gusella JF. BanI polymorphism at the XBP1 locus. Nucleic Acids Research. 18: 5578. PMID 1977120 DOI: 10.1093/Nar/18.18.5578-A  1
1990 Wuthrich RP, Jevnikar AM, Takei F, Glimcher LH, Kelley VE. Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis American Journal of Pathology. 136: 441-450. PMID 1968316  1
1989 Ghogawala Z, Choi E, Daly KR, Blanco LR, Griffith IJ, Glimcher LH. An intronic 10-base-pair deletion in a class II Aβ gene affects RNA processing Molecular and Cellular Biology. 9: 4402-4408. PMID 2555693 DOI: 10.1128/Mcb.9.10.4402  1
1989 Boothby M, Liou HC, Glimcher LH. Differences in DNA sequence specificity among MHC class II X box binding proteins Journal of Immunology. 142: 1005-1014. PMID 2492326  1
1989 Gravallese EM, Boothby MR, Smas CM, Glimcher LH. A lipopolysaccharide-induced DNA-binding protein for a class II gene in B cells is distinct from NF-κB Molecular and Cellular Biology. 9: 3184-3192. PMID 2477682 DOI: 10.1128/Mcb.9.8.3184  1
1989 St-Pierre Y, Nabavi N, Ghogawala Z, Glimcher LH, Watts TH. A functional role for signal transduction via the cytoplasmic domains of MHC class II proteins Journal of Immunology. 143: 808-812. PMID 2473111  1
1989 Johnson NA, Carland F, Allen PM, Glimcher LH. T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-A(k)-restricted T helper hybridomas Journal of Immunology. 142: 3298-3304. PMID 2468715  1
1988 McMillan VM, Dennis GJ, Glimcher LH, Finkelman FD, Mond JJ. Corticosteroid induction of Ig+Ia- B cells in vitro is mediated via interaction with the glucocorticoid cytoplasmic receptor Journal of Immunology. 140: 2549-2555. PMID 3258614  1
1988 Boothby M, Gravallese E, Liou HC, Glimcher LH. A DNA binding protein regulated by IL-4 and by differentiation in B cells Science. 242: 1559-1562. PMID 3144043 DOI: 10.1126/Science.3144043  1
1988 Liou HC, Boothby MR, Glimcher LH. Distinct cloned class II MHC DNA binding proteins recognize the X box transcription element Science. 242: 69-71. PMID 3140376 DOI: 10.1126/Science.3140376  1
1988 Griffith IJ, Nabavi N, Ghogawala Z, Chase CG, Rodriguez M, McKean DJ, Glimcher LH. Structural mutation affecting intracellular transport and cell surface expression of murine class II molecules. The Journal of Experimental Medicine. 167: 541-55. PMID 3126253 DOI: 10.1084/Jem.167.2.541  1
1988 Griffith IJ, Ghogawala Z, Nabavi N, Golan DE, Myer A, McKean DJ, Glimcher LH. Cytoplasmic domain affects membrane expression and function of an Ia molecule. Proceedings of the National Academy of Sciences of the United States of America. 85: 4847-51. PMID 2838848 DOI: 10.1073/Pnas.85.13.4847  1
1987 Takahama Y, Ono S, Glimcher LH, Hamaoka T. Polyclonal B-cell activation by a B-cell differentiation factor B151-TRF2. IV. B151-TRF2-responsive F1 B cells consist of two separate populations capable of recognizing only one of the parental I-A products expressed on B cells Journal of Molecular and Cellular Immunology. 3: 177-194. PMID 3509923  1
1987 Griffith IJ, Choi EM, Glimcher LH. A single base mutation in an I-A α-chain gene alters T-cell recognition Proceedings of the National Academy of Sciences of the United States of America. 84: 1090-1093. PMID 3493486 DOI: 10.1073/Pnas.84.4.1090  1
1987 Glimcher LH, Polla BS, Poljak A, Morton CC, McKean DJ. Murine class II (Ia) molecules associate with human invariant chain Journal of Immunology. 138: 1519-1523. PMID 3468175  1
1987 Griffith IJ, Carland FM, Glimcher LH. Alteration of a non-polymorphic residue in a class II E(β) gene eliminates an antibody-defined epitope without affecting T cell recognition Journal of Immunology. 138: 4480-4483. PMID 2438346  1
1987 Glimcher LH, Griffith IJ. Mutations of class II MHC molecules Trends in Immunology. 8: 279-282. DOI: 10.1016/0167-5699(87)90188-5  1
1986 Polla BS, Poljak A, Geier SG, Nathenson SG, Ohara J, Paul WE, Glimcher LH. Three distinct signals can induce class II gene expression in a murine pre-B-cell line. Proceedings of the National Academy of Sciences of the United States of America. 83: 4878-82. PMID 3487783 DOI: 10.1073/Pnas.83.13.4878  0.96
1986 Polla BS, Poljak A, Ohara J, Paul WE, Glimcher LH. Regulation of class II gene expression: Analysis in B cell stimulatory factor 1-inducible murine pre-B cell lines Journal of Immunology. 137: 3332-3337. PMID 3095428  1
1986 Quill H, Schwartz RH, Glimcher LH. E(β)(k) mutant antigen-presenting cell lines expressing altered A(α)(k) molecules Journal of Immunology. 136: 3351-3359. PMID 3082986  1
1986 Chatterjee-Das S, Schlauder GG, Sachs DH, Glimcher LH, Paul WE, McKean DJ. A biochemical analysis of Ak molecules from mutant antigen presenting cell lines. Immunogenetics. 23: 121-5. PMID 3082750 DOI: 10.1007/Bf00377972  0.96
1985 Malek TR, Chan C, Glimcher LH, Germain RN, Shevach EM. Influence of accessory cell and T cell surface antigens on mitogen-induced IL 2 receptor expression Journal of Immunology. 135: 1826-1833. PMID 3926885  1
1985 Ben-Nun A, Strauss W, Leeman SA, Cohn LE, Murre C, Duby A, Seidman JG, Glimcher LH. An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells. Immunogenetics. 22: 123-30. PMID 3875550 DOI: 10.1007/Bf00563509  1
1985 Schlauder GG, Bell MP, paul WE, Glimcher LH, McKean DJ. Biochemical characterization of I-Ak proteins from mutant antigen-presenting B-cell-B-lymphoma hybridomas Molecular Immunology. 22: 597-607. PMID 3875018 DOI: 10.1016/0161-5890(85)90184-1  1
1985 Mizuochi T, Golding H, Rosenberg AS, Glimcher LH, Malek TR, Singer A. Both L3T4+ and Lyt-2+ helper T cells initiate cytotoxic T lymphocyte responses against allogeneic major histocompatibility antigens but not against trinitrophenyl-modified self Journal of Experimental Medicine. 162: 427-443. PMID 3160804 DOI: 10.1084/Jem.162.2.427  1
1985 Glimcher LH, Schwartz RH. Analysis of responder cell-cell interactions in the syngeneic mixed leukocyte response Cellular Immunology. 93: 157-167. PMID 3158406 DOI: 10.1016/0008-8749(85)90396-X  1
1985 Glimcher LH, McKean DJ, Choi E, Seidman JG. Complex regulation of class II gene expression: Analysis with class II mutant cell lines Journal of Immunology. 135: 3542-3550. PMID 2995495  1
1985 Makoul GT, Robinson DR, Bhalla AK, Glimcher LH. Prostaglandin E2 inhibits the activation of cloned T cell hybridomas Journal of Immunology. 134: 2645-2659. PMID 2857750  1
1985 Glimcher LH, Serog B, McKean DJ, Beck BN. Evidence that autoreactive T hybridomas recognize multiple epitopes on the I-A(k) molecule Journal of Immunology. 134: 1780-1786. PMID 2578521  1
1985 Allen PM, McKean DJ, Beck BN, Sheffield J, Glimcher LH. Direct evidence that a class II molecule and a simple globular protein generate multiple determinants Journal of Experimental Medicine. 162: 1264-1274. PMID 2413156 DOI: 10.1084/Jem.162.4.1264  1
1985 Heilig JS, Glimcher LH, Kranz DM, Clayton LK, Greenstein JL, Saito H, Maxam AM, Burakoff SJ, Eisen HN, Tonegawa S. Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants. Nature. 317: 68-70. PMID 2412133 DOI: 10.1038/317068A0  1
1985 Glimcher LH, McKean DJ, Allen P. Autoreactive and hen egg lysozyme (HEL)-specific T cell hybridomas recognize multiple determinants on the I-A(K) molecule Federation Proceedings. 44.  1
1984 Cronin PS, Sing AP, Glimcher LH, Kelley VE, Reinisch CL. The isolation and functional characterization of autoimmune clones expressing inappropriate Ia Journal of Immunology. 133: 822-829. PMID 6610712  1
1984 Ben-Nun A, Glimcher LH, Weis J, Seidman JG. Functional expression of a cloned I-Aβk gene in B-lymphoma cells Science. 223: 825-828. PMID 6420890 DOI: 10.1126/Science.6420890  1
1984 Beck BN, Glimcher LH, Nilson AE, Pierres M, McKean DJ. The structure-function relationship of I-A molecules: Correlation of serologic and functional phenotypes of four I-A(k) mutant cell lines Journal of Immunology. 133: 3176-3182. PMID 6333456  1
1984 Bhalla AK, Amento EP, Serog B, Glimcher LH. 1,25-dihydroxyvitamin D3 inhibits antigen-induced T cell activation Journal of Immunology. 133: 1748-1754. PMID 6206136  1
1983 Matis LA, Glimcher LH, Paul WE, Schwartz RH. Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules Proceedings of the National Academy of Sciences of the United States of America. 80: 6019-6023. PMID 6310611 DOI: 10.1073/Pnas.80.19.6019  1
1983 Glimcher LH, Kruisbeek AM, Paul WE, Green I. Functional activity of a transformed thymic epithelial cell line Scandinavian Journal of Immunology. 17: 1-11. PMID 6302828 DOI: 10.1111/J.1365-3083.1983.Tb00759.X  1
1983 Dos Reis GA, Glimcher LH, Shevach EM. T cell clones and hybridomas as probes for the analysis of the syngeneic mixed leukocyte reaction Behring Institute Mitteilungen. 59-66. PMID 6242340  1
1983 Glimcher LH, Schroer JA, Chan C, Shevach EM. Fine specificity of cloned insulin-specific T cell hybridomas: Evidence supporting a role for tertiary conformation Journal of Immunology. 131: 2868-2874. PMID 6196405  1
1983 Glimcher LH, Sharrow SO, Paul WE. Serologic and functional characterization of a panel of antigen-presenting cell lines expressing mutant I-A class II molecules Journal of Experimental Medicine. 158: 1573-1588. PMID 6195287 DOI: 10.1084/Jem.158.5.1573  1
1983 Glimcher LH, Paul WE. Class II MHC antigens and immune response gene function: A mutational analysis Transplantation Proceedings. 15: 1753-1755.  1
1982 Glimcher LH, Cantor H. T-cell sets that control B-cell secretion of antigen-specific immunoglobulin also control secretion of nonspecific immunoglobulin Cellular Immunology. 70: 271-276. PMID 6982104 DOI: 10.1016/0008-8749(82)90328-8  1
1982 Glimcher LH, Kim KJ, Green I, Paul WE. Ia antigen-bearing B cell tumor lines can present protein antigen and alloantigen in a major histocompatibility complex-restricted fashion to antigen-reactive T cells Journal of Experimental Medicine. 155: 445-459. PMID 6460073 DOI: 10.1084/Jem.155.2.445  1
1982 Glimcher LH, Schwartz RH, Longo DL, Singer A. The specificity of the syngeneic mixed leukocyte response, a primary anti-I region T cell proliferative response, is determined intrathymically Journal of Immunology. 129: 987-991. PMID 6213713  1
1982 Glimcher LH, Shevach EM. Production of autoreactive I region-restricted T cell hybridomas Journal of Experimental Medicine. 156: 640-645. PMID 6212627 DOI: 10.1084/Jem.156.2.640  1
1982 Glimcher LH, Hamano T, Asofsky R, Herber-Katz E, Hedrick S, Schwartz RH, Paul WE. I region-restricted antigen presentation by B cell-B lymphoma hybridomas. Nature. 298: 283-4. PMID 6211627 DOI: 10.1038/298283A0  1
1982 Schwartz RH, Glimcher LH, Hedrick SM. Restriction of thymic major histocompatibility complex (MHC)- and immune response (Ir)-phenotype of T cells from allogeneic chimeras Behring Institute Mitteilungen. 155-162.  1
1981 Glimcher LH, Longo DL, Green I, Schwartz RH. Murine syngeneic mixed lymphocyte response. I. Target antigens are self Ia molecules Journal of Experimental Medicine. 154: 1652-1670. PMID 6170721 DOI: 10.1084/Jem.154.5.1652  1
1980 Glimcher LH, Steinberg AD, House SB, Green I. The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease Journal of Immunology. 125: 1832-1838. PMID 6447732  1
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