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Laurie H. Glimcher - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Immunology, Molecular Biology, Microbiology Biology
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Year Citation  Score
2020 Yang R, Mele F, Worley L, Langlais D, Rosain J, Benhsaien I, Elarabi H, Croft CA, Doisne JM, Zhang P, Weisshaar M, Jarrossay D, Latorre D, Shen Y, Han J, ... ... Glimcher LH, et al. Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria. Cell. PMID 33296702 DOI: 10.1016/j.cell.2020.10.046  0.305
2020 Glimcher LH, Lee AH, Iwakoshi NN. XBP-1 and the unfolded protein response (UPR). Nature Immunology. PMID 32616861 DOI: 10.1038/S41590-020-0708-3  0.33
2019 Dong H, Adams NM, Xu Y, Cao J, Allan DSJ, Carlyle JR, Chen X, Sun JC, Glimcher LH. The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc. Nature Immunology. PMID 31086333 DOI: 10.1038/S41590-019-0388-Z  0.371
2018 Song M, Sandoval TA, Chae CS, Chopra S, Tan C, Rutkowski MR, Raundhal M, Chaurio RA, Payne KK, Konrad C, Bettigole SE, Shin HR, Crowley MJP, Cerliani JP, Kossenkov AV, ... ... Glimcher LH, et al. IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity. Nature. PMID 30305738 DOI: 10.1038/S41586-018-0597-X  0.415
2018 Xu R, Yallowitz A, Qin A, Wu Z, Shin DY, Kim JM, Debnath S, Ji G, Bostrom MP, Yang X, Zhang C, Dong H, Kermani P, Lalani S, Li N, ... ... Glimcher LH, et al. Targeting skeletal endothelium to ameliorate bone loss. Nature Medicine. PMID 29785024 DOI: 10.1038/S41591-018-0020-Z  0.307
2017 Lazarevic V, Szabo S, Glimcher LH. T-bet Runs INTERFERence. Immunity. 46: 968-970. PMID 28636963 DOI: 10.1016/J.Immuni.2017.05.010  0.379
2017 Adoro S, Park KH, Bettigole SE, Lis R, Shin HR, Seo H, Kim JH, Knobeloch KP, Shim JH, Glimcher LH. Post-translational control of T cell development by the ESCRT protein CHMP5. Nature Immunology. PMID 28553951 DOI: 10.1038/Ni.3764  0.446
2017 Xu Z, Greenblatt MB, Yan G, Feng H, Sun J, Lotinun S, Brady N, Baron R, Glimcher LH, Zou W. SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts. Nature Communications. 8: 14570. PMID 28216630 DOI: 10.1038/Ncomms14570  0.356
2016 Liu CF, Brandt GS, Hoang QQ, Naumova N, Lazarevic V, Hwang ES, Dekker J, Glimcher LH, Ringe D, Petsko GA. Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites. Proceedings of the National Academy of Sciences of the United States of America. 113: E6572-E6581. PMID 27791029 DOI: 10.1073/Pnas.1613914113  0.416
2016 Cubillos-Ruiz JR, Glimcher LH. Targeting abnormal ER stress responses in tumors: A new approach to cancer immunotherapy. Oncoimmunology. 5: e1098802. PMID 27141359 DOI: 10.1080/2162402X.2015.1098802  0.312
2016 Cubillos-Ruiz JR, Bettigole SE, Glimcher LH. Molecular Pathways: Immunosuppressive Roles of IRE1α-XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26979393 DOI: 10.1158/1078-0432.Ccr-15-1570  0.334
2015 Cameron TL, Bell KM, Gresshoff IL, Sampurno L, Mullan L, Ermann J, Glimcher LH, Boot-Handford RP, Bateman JF. XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease. Plos Genetics. 11: e1005505. PMID 26372225 DOI: 10.1371/Journal.Pgen.1005505  0.337
2015 Bettigole SE, Lis R, Adoro S, Lee AH, Spencer LA, Weller PF, Glimcher LH. The transcription factor XBP1 is selectively required for eosinophil differentiation. Nature Immunology. PMID 26147683 DOI: 10.1038/Ni.3225  0.325
2015 Adoro S, Cubillos-Ruiz JR, Chen X, Deruaz M, Vrbanac VD, Song M, Park S, Murooka TT, Dudek TE, Luster AD, Tager AM, Streeck H, Bowman B, Walker BD, Kwon DS, ... ... Glimcher LH, et al. IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection. Nature Communications. 6: 7562. PMID 26108174 DOI: 10.1038/Ncomms8562  0.301
2015 Cubillos-Ruiz JR, Silberman PC, Rutkowski MR, Chopra S, Perales-Puchalt A, Song M, Zhang S, Bettigole SE, Gupta D, Holcomb K, Ellenson LH, Caputo T, Lee AH, Conejo-Garcia JR, Glimcher LH. ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis. Cell. 161: 1527-38. PMID 26073941 DOI: 10.1016/J.Cell.2015.05.025  0.332
2015 Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. Pillars article: A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 2000. 100: 655-669. Journal of Immunology (Baltimore, Md. : 1950). 194: 2961-75. PMID 25795787  0.306
2015 Cameron TL, Gresshoff IL, Bell KM, Piróg KA, Sampurno L, Hartley CL, Sanford EM, Wilson R, Ermann J, Boot-Handford RP, Glimcher LH, Briggs MD, Bateman JF. Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 23: 661-70. PMID 25600960 DOI: 10.1016/J.Joca.2015.01.001  0.303
2015 Singh A, Lester C, Drapp R, Hu DZ, Glimcher LH, Jones D. Tetraspanin CD9 and ectonucleotidase CD73 identify an osteochondroprogenitor population with elevated osteogenic properties. Development (Cambridge, England). 142: 438-43. PMID 25564652 DOI: 10.1242/Dev.113571  0.336
2015 Bettigole SE, Glimcher LH. Endoplasmic reticulum stress in immunity. Annual Review of Immunology. 33: 107-38. PMID 25493331 DOI: 10.1146/Annurev-Immunol-032414-112116  0.307
2015 Greenblatt MB, Kim JM, Oh H, Park KH, Choo MK, Sano Y, Tye CE, Skobe Z, Davis RJ, Park JM, Bei M, Glimcher LH, Shim JH. p38α MAPK is required for tooth morphogenesis and enamel secretion. The Journal of Biological Chemistry. 290: 284-95. PMID 25406311 DOI: 10.1074/Jbc.M114.599274  0.348
2014 Ermann J, Staton T, Glickman JN, de Waal Malefyt R, Glimcher LH. Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice. Proceedings of the National Academy of Sciences of the United States of America. 111: E2559-66. PMID 24927559 DOI: 10.1073/Pnas.1408540111  0.346
2014 Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt MB, Hatziapostolou M, Lim E, Tam WL, Ni M, Chen Y, Mai J, Shen H, Hu DZ, Adoro S, Hu B, ... ... Glimcher LH, et al. XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway. Nature. 508: 103-7. PMID 24670641 DOI: 10.1038/Nature13119  0.307
2013 Greenblatt MB, Ritter SY, Wright J, Tsang K, Hu D, Glimcher LH, Aliprantis AO. NFATc1 and NFATc2 repress spontaneous osteoarthritis. Proceedings of the National Academy of Sciences of the United States of America. 110: 19914-9. PMID 24248346 DOI: 10.1073/Pnas.1320036110  0.364
2013 Lazarevic V, Glimcher LH, Lord GM. T-bet: A bridge between innate and adaptive immunity Nature Reviews Immunology. 13: 777-789. PMID 24113868 DOI: 10.1038/Nri3536  0.44
2013 Shim JH, Greenblatt MB, Zou W, Huang Z, Wein MN, Brady N, Hu D, Charron J, Brodkin HR, Petsko GA, Zaller D, Zhai B, Gygi S, Glimcher LH, Jones DC. Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts. The Journal of Clinical Investigation. 123: 4010-22. PMID 23945236 DOI: 10.1172/Jci69443  0.724
2013 Zou W, Greenblatt MB, Brady N, Lotinun S, Zhai B, de Rivera H, Singh A, Sun J, Gygi SP, Baron R, Glimcher LH, Jones DC. The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2. The Journal of Experimental Medicine. 210: 1793-806. PMID 23918955 DOI: 10.1084/Jem.20111790  0.369
2013 Greenblatt MB, Shim JH, Glimcher LH. Mitogen-activated protein kinase pathways in osteoblasts. Annual Review of Cell and Developmental Biology. 29: 63-79. PMID 23725048 DOI: 10.1146/Annurev-Cellbio-101512-122347  0.325
2013 Cho JA, Lee AH, Platzer B, Cross BC, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. Cell Host & Microbe. 13: 558-69. PMID 23684307 DOI: 10.1016/J.Chom.2013.03.011  0.343
2013 Masouleh BK, Geng H, Hurtz C, Huang C, Chan LN, Swaminathan S, Sun H, Koeffler HP, Melnick A, Paietta E, Glimcher LH, Muschen M. The Plasma Cell Transcription Factor XBP1 is Required To Mitigate The Unfolded Protein Response In Ph+ ALL Blood. 122: 836-836. DOI: 10.1182/Blood.V122.21.836.836  0.386
2012 So JS, Hur KY, Tarrio M, Ruda V, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Lichtman AH, Iwawaki T, Glimcher LH, Lee AH. Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. Cell Metabolism. 16: 487-99. PMID 23040070 DOI: 10.1016/J.Cmet.2012.09.004  0.308
2012 Fu W, Ergun A, Lu T, Hill JA, Haxhinasto S, Fassett MS, Gazit R, Adoro S, Glimcher L, Chan S, Kastner P, Rossi D, Collins JJ, Mathis D, Benoist C. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nature Immunology. 13: 972-80. PMID 22961053 DOI: 10.1038/Ni.2420  0.452
2012 Wein MN, Jones DC, Shim JH, Aliprantis AO, Sulyanto R, Lazarevic V, Poliachik SL, Gross TS, Glimcher LH. Control of bone resorption in mice by Schnurri-3. Proceedings of the National Academy of Sciences of the United States of America. 109: 8173-8. PMID 22573816 DOI: 10.1073/Pnas.1205848109  0.675
2012 Vidal RL, Figueroa A, Court FA, Thielen P, Molina C, Wirth C, Caballero B, Kiffin R, Segura-Aguilar J, Cuervo AM, Glimcher LH, Hetz C. Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy. Human Molecular Genetics. 21: 2245-62. PMID 22337954 DOI: 10.1093/Hmg/Dds040  0.346
2012 Hur KY, So JS, Ruda V, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Iwawaki T, Glimcher LH, Lee AH. IRE1α activation protects mice against acetaminophen-induced hepatotoxicity. The Journal of Experimental Medicine. 209: 307-18. PMID 22291093 DOI: 10.1084/Jem.20111298  0.316
2012 Greenblatt MB, Sargent JL, Farina G, Tsang K, Lafyatis R, Glimcher LH, Whitfield ML, Aliprantis AO. Interspecies comparison of human and murine scleroderma reveals IL-13 and CCL2 as disease subset-specific targets. The American Journal of Pathology. 180: 1080-94. PMID 22245215 DOI: 10.1016/J.Ajpath.2011.11.024  0.318
2012 Shim JH, Greenblatt MB, Singh A, Brady N, Hu D, Drapp R, Ogawa W, Kasuga M, Noda T, Yang SH, Lee SK, Rebel VI, Glimcher LH. Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice. The Journal of Clinical Investigation. 122: 91-106. PMID 22133875 DOI: 10.1172/Jci59466  0.382
2012 Masouleh BK, Hurtz C, Geng H, Ramezani-Rad P, Glimcher LH, Muschen M. Targeting the UPR-Transcription Factor XBP1 to Overcome Drug-Resistance in Ph+ ALL Blood. 120: 872-872. DOI: 10.1182/Blood.V120.21.872.872  0.379
2011 Wan L, Zou W, Gao D, Inuzuka H, Fukushima H, Berg AH, Drapp R, Shaik S, Hu D, Lester C, Eguren M, Malumbres M, Glimcher LH, Wei W. Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. Molecular Cell. 44: 721-33. PMID 22152476 DOI: 10.1016/J.Molcel.2011.09.024  0.348
2011 Zou W, Greenblatt MB, Shim JH, Kant S, Zhai B, Lotinun S, Brady N, Hu DZ, Gygi SP, Baron R, Davis RJ, Jones D, Glimcher LH. MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice. The Journal of Clinical Investigation. 121: 4383-92. PMID 21965325 DOI: 10.1172/Jci59041  0.35
2011 Hess DA, Humphrey SE, Ishibashi J, Damsz B, Lee AH, Glimcher LH, Konieczny SF. Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice. Gastroenterology. 141: 1463-72. PMID 21704586 DOI: 10.1053/J.Gastro.2011.06.045  0.36
2011 Lazarevic V, Glimcher LH. T-bet in disease. Nature Immunology. 12: 597-606. PMID 21685955 DOI: 10.1038/Ni.2059  0.427
2011 Lee AH, Heidtman K, Hotamisligil GS, Glimcher LH. Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion. Proceedings of the National Academy of Sciences of the United States of America. 108: 8885-90. PMID 21555585 DOI: 10.1073/Pnas.1105564108  0.352
2011 Ermann J, Garrett WS, Kuchroo J, Rourida K, Glickman JN, Bleich A, Glimcher LH. Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus. Proceedings of the National Academy of Sciences of the United States of America. 108: 7137-41. PMID 21482794 DOI: 10.1073/Pnas.1104234108  0.408
2011 Staton TL, Lazarevic V, Jones DC, Lanser AJ, Takagi T, Ishii S, Glimcher LH. Dampening of death pathways by schnurri-2 is essential for T-cell development. Nature. 472: 105-9. PMID 21475200 DOI: 10.1038/Nature09848  0.391
2011 Hetz C, Glimcher LH. Protein homeostasis networks in physiology and disease. Current Opinion in Cell Biology. 23: 123-5. PMID 21306885 DOI: 10.1016/J.Ceb.2011.01.004  0.302
2011 Zou W, Chen X, Shim JH, Huang Z, Brady N, Hu D, Drapp R, Sigrist K, Glimcher LH, Jones D. The E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of Goosecoid. Nature Cell Biology. 13: 59-65. PMID 21170031 DOI: 10.1038/Ncb2134  0.511
2011 Lazarevic V, Chen X, Shim JH, Hwang ES, Jang E, Bolm AN, Oukka M, Kuchroo VK, Glimcher LH. T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt. Nature Immunology. 12: 96-104. PMID 21151104 DOI: 10.1038/Ni.1969  0.451
2011 Martinon F, Glimcher LH. Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum. Current Opinion in Immunology. 23: 35-40. PMID 21094031 DOI: 10.1016/J.Coi.2010.10.016  0.325
2011 Lazarevic V, Ermann J, Garrett WS, Glimcher LH. HL1. T-bet in Inflammatory Diseases Cytokine. 56: 2. DOI: 10.1016/J.Cyto.2011.07.290  0.316
2010 Veiga P, Gallini CA, Beal C, Michaud M, Delaney ML, DuBois A, Khlebnikov A, van Hylckama Vlieg JE, Punit S, Glickman JN, Onderdonk A, Glimcher LH, Garrett WS. Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes. Proceedings of the National Academy of Sciences of the United States of America. 107: 18132-7. PMID 20921388 DOI: 10.1073/Pnas.1011737107  0.315
2010 Huh WJ, Esen E, Geahlen JH, Bredemeyer AJ, Lee AH, Shi G, Konieczny SF, Glimcher LH, Mills JC. XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum. Gastroenterology. 139: 2038-49. PMID 20816838 DOI: 10.1053/J.Gastro.2010.08.050  0.386
2010 Collins PL, Chang S, Henderson M, Soutto M, Davis GM, McLoed AG, Townsend MJ, Glimcher LH, Mortlock DP, Aune TM. Distal regions of the human IFNG locus direct cell type-specific expression. Journal of Immunology (Baltimore, Md. : 1950). 185: 1492-501. PMID 20574006 DOI: 10.4049/Jimmunol.1000124  0.405
2010 Greenblatt MB, Shim JH, Zou W, Sitara D, Schweitzer M, Hu D, Lotinun S, Sano Y, Baron R, Park JM, Arthur S, Xie M, Schneider MD, Zhai B, Gygi S, ... ... Glimcher LH, et al. The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. The Journal of Clinical Investigation. 120: 2457-73. PMID 20551513 DOI: 10.1172/Jci42285  0.356
2010 Greenblatt MB, Aliprantis A, Hu B, Glimcher LH. Calcineurin regulates innate antifungal immunity in neutrophils. The Journal of Experimental Medicine. 207: 923-31. PMID 20421389 DOI: 10.1084/Jem.20092531  0.38
2010 Jones DC, Schweitzer MN, Wein M, Sigrist K, Takagi T, Ishii S, Glimcher LH. Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3. Proceedings of the National Academy of Sciences of the United States of America. 107: 8254-8. PMID 20404140 DOI: 10.1073/Pnas.1003727107  0.675
2010 Greenblatt MB, Shim JH, Glimcher LH. TAK1 mediates BMP signaling in cartilage. Annals of the New York Academy of Sciences. 1192: 385-90. PMID 20392264 DOI: 10.1111/J.1749-6632.2009.05222.X  0.325
2010 Martinon F, Chen X, Lee AH, Glimcher LH. TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nature Immunology. 11: 411-8. PMID 20351694 DOI: 10.1038/Ni.1857  0.331
2010 Fathman JW, Gurish MF, Hemmers S, Bonham K, Friend DS, Grusby MJ, Glimcher LH, Mowen KA. NIP45 controls the magnitude of the type 2 T helper cell response. Proceedings of the National Academy of Sciences of the United States of America. 107: 3663-8. PMID 20133688 DOI: 10.1073/Pnas.0914700107  0.494
2010 Riol-Blanco L, Lazarevic V, Awasthi A, Mitsdoerffer M, Wilson BS, Croxford A, Waisman A, Kuchroo VK, Glimcher LH, Oukka M. IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections. Journal of Immunology (Baltimore, Md. : 1950). 184: 1710-20. PMID 20083652 DOI: 10.4049/Jimmunol.0902796  0.382
2010 Anderson AC, Lord GM, Dardalhon V, Lee DH, Sabatos-Peyton CA, Glimcher LH, Kuchroo VK. T-bet, a Th1 transcription factor regulates the expression of Tim-3. European Journal of Immunology. 40: 859-66. PMID 20049876 DOI: 10.1002/Eji.200939842  0.447
2010 Glimcher LH. XBP1: The last two decades Annals of the Rheumatic Diseases. 69. PMID 19995749 DOI: 10.1136/Ard.2009.119388  0.346
2010 Jones DC, Glimcher LH. Regulation of bone formation and immune cell development by Schnurri proteins. Advances in Experimental Medicine and Biology. 658: 117-22. PMID 19950022 DOI: 10.1007/978-1-4419-1050-9_13  0.367
2010 Aliprantis AO, Glimcher LH. NFATc1 in inflammatory and musculoskeletal conditions. Advances in Experimental Medicine and Biology. 658: 69-75. PMID 19950017 DOI: 10.1007/978-1-4419-1050-9_8  0.412
2010 Glimcher LH, Lazarevic V, Ermann J, Garrett W. A Commitment to Lineage Blood. 116: SCI-22-SCI-22. DOI: 10.1182/Blood.V116.21.Sci-22.Sci-22  0.451
2009 Matus S, Nassif M, Glimcher LH, Hetz C. XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy. Autophagy. 5: 1226-8. PMID 19855189 DOI: 10.4161/Auto.5.8.10247  0.329
2009 Jenner RG, Townsend MJ, Jackson I, Sun K, Bouwman RD, Young RA, Glimcher LH, Lord GM. The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. Proceedings of the National Academy of Sciences of the United States of America. 106: 17876-81. PMID 19805038 DOI: 10.1073/Pnas.0909357106  0.464
2009 Hetz C, Thielen P, Matus S, Nassif M, Court F, Kiffin R, Martinez G, Cuervo AM, Brown RH, Glimcher LH. XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes & Development. 23: 2294-306. PMID 19762508 DOI: 10.1101/Gad.1830709  0.334
2009 Todd DJ, McHeyzer-Williams LJ, Kowal C, Lee AH, Volpe BT, Diamond B, McHeyzer-Williams MG, Glimcher LH. XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development. The Journal of Experimental Medicine. 206: 2151-9. PMID 19752183 DOI: 10.1084/Jem.20090738  0.379
2009 Hetz C, Glimcher LH. Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome. Molecular Cell. 35: 551-61. PMID 19748352 DOI: 10.1016/J.Molcel.2009.08.021  0.3
2009 Garrett WS, Punit S, Gallini CA, Michaud M, Zhang D, Sigrist KS, Lord GM, Glickman JN, Glimcher LH. Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells. Cancer Cell. 16: 208-19. PMID 19732721 DOI: 10.1016/J.Ccr.2009.07.015  0.372
2009 Garrett WS, Glimcher LH. T-bet-/- RAG2-/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships. Cytokine. 48: 144-7. PMID 19666230 DOI: 10.1016/J.Cyto.2009.07.007  0.378
2009 Shim JH, Greenblatt MB, Xie M, Schneider MD, Zou W, Zhai B, Gygi S, Glimcher LH. TAK1 is an essential regulator of BMP signalling in cartilage. The Embo Journal. 28: 2028-41. PMID 19536134 DOI: 10.1038/Emboj.2009.162  0.355
2009 Esensten JH, Lee MR, Glimcher LH, Bluestone JA. T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function. Journal of Immunology (Baltimore, Md. : 1950). 183: 75-82. PMID 19535634 DOI: 10.4049/Jimmunol.0804154  0.427
2009 Yuan X, Ansari MJ, D'Addio F, Paez-Cortez J, Schmitt I, Donnarumma M, Boenisch O, Zhao X, Popoola J, Clarkson MR, Yagita H, Akiba H, Freeman GJ, Iacomini J, Turka LA, ... Glimcher LH, et al. Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 10734-9. PMID 19528638 DOI: 10.1073/Pnas.0812538106  0.383
2009 Maldonado RA, Soriano MA, Perdomo LC, Sigrist K, Irvine DJ, Decker T, Glimcher LH. Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse. The Journal of Experimental Medicine. 206: 877-92. PMID 19349465 DOI: 10.1084/Jem.20082900  0.408
2009 Lisbona F, Rojas-Rivera D, Thielen P, Zamorano S, Todd D, Martinon F, Glavic A, Kress C, Lin JH, Walter P, Reed JC, Glimcher LH, Hetz C. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Molecular Cell. 33: 679-91. PMID 19328063 DOI: 10.1016/J.Molcel.2009.02.017  0.33
2009 Lazarevic V, Zullo AJ, Schweitzer MN, Staton TL, Gallo EM, Crabtree GR, Glimcher LH. The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells. Nature Immunology. 10: 306-13. PMID 19169262 DOI: 10.1038/Ni.1696  0.459
2009 Park JW, Min HJ, Sohn JH, Kim JY, Hong JH, Sigrist KS, Glimcher LH, Hwang ES. Restoration of T-box-containing protein expressed in T cells protects against allergen-induced asthma. The Journal of Allergy and Clinical Immunology. 123: 479-85. PMID 19081613 DOI: 10.1016/J.Jaci.2008.10.035  0.406
2008 Yuan X, Paez-Cortez J, Schmitt-Knosalla I, D'Addio F, Mfarrej B, Donnarumma M, Habicht A, Clarkson MR, Iacomini J, Glimcher LH, Sayegh MH, Ansari MJ. A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy. The Journal of Experimental Medicine. 205: 3133-44. PMID 19047438 DOI: 10.1084/Jem.20081937  0.4
2008 Wu J, Glimcher LH, Aliprantis AO. HCO3-/Cl- anion exchanger SLC4A2 is required for proper osteoclast differentiation and function. Proceedings of the National Academy of Sciences of the United States of America. 105: 16934-9. PMID 18971331 DOI: 10.1073/Pnas.0808763105  0.397
2008 Aliprantis AO, Ueki Y, Sulyanto R, Park A, Sigrist KS, Sharma SM, Ostrowski MC, Olsen BR, Glimcher LH. NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. The Journal of Clinical Investigation. 118: 3775-89. PMID 18846253 DOI: 10.1172/Jci35711  0.4
2008 Kaser A, Lee AH, Franke A, Glickman JN, Zeissig S, Tilg H, Nieuwenhuis EE, Higgins DE, Schreiber S, Glimcher LH, Blumberg RS. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell. 134: 743-56. PMID 18775308 DOI: 10.1016/J.Cell.2008.07.021  0.321
2008 Todd DJ, Lee AH, Glimcher LH. The endoplasmic reticulum stress response in immunity and autoimmunity. Nature Reviews. Immunology. 8: 663-74. PMID 18670423 DOI: 10.1038/Nri2359  0.307
2008 Lee AH, Scapa EF, Cohen DE, Glimcher LH. Regulation of hepatic lipogenesis by the transcription factor XBP1. Science (New York, N.Y.). 320: 1492-6. PMID 18556558 DOI: 10.1126/Science.1158042  0.323
2008 Werneck MB, Lugo-Villarino G, Hwang ES, Cantor H, Glimcher LH. T-bet plays a key role in NK-mediated control of melanoma metastatic disease. Journal of Immunology (Baltimore, Md. : 1950). 180: 8004-10. PMID 18523263 DOI: 10.4049/Jimmunol.180.12.8004  0.727
2008 Wein MN, Jones DC, Glimcher LH. Lentivirus delivery of shRNA constructs into osteoblasts. Methods in Molecular Biology (Clifton, N.J.). 455: 149-55. PMID 18463817 DOI: 10.1007/978-1-59745-104-8_11  0.679
2008 Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW. Functional Th1 cells are required for surgical adhesion formation in a murine model. Journal of Immunology (Baltimore, Md. : 1950). 180: 6970-6. PMID 18453619 DOI: 10.4049/Jimmunol.180.10.6970  0.434
2008 Karwot R, Maxeiner JH, Schmitt S, Scholtes P, Hausding M, Lehr HA, Glimcher LH, Finotto S. Protective role of nuclear factor of activated T cells 2 in CD8+ long-lived memory T cells in an allergy model. The Journal of Allergy and Clinical Immunology. 121: 992-9.e6. PMID 18329088 DOI: 10.1016/J.Jaci.2007.12.1172  0.448
2008 Horsley V, Aliprantis AO, Polak L, Glimcher LH, Fuchs E. NFATc1 balances quiescence and proliferation of skin stem cells. Cell. 132: 299-310. PMID 18243104 DOI: 10.1016/J.Cell.2007.11.047  0.308
2008 Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, ... ... Glimcher LH, et al. Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. The Journal of Clinical Investigation. 118: 491-504. PMID 18219387 DOI: 10.1172/Jci33102  0.672
2008 Hetz C, Lee AH, Gonzalez-Romero D, Thielen P, Castilla J, Soto C, Glimcher LH. Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 757-62. PMID 18178615 DOI: 10.1073/Pnas.0711094105  0.317
2008 Rengarajan J, Murphy E, Park A, Krone CL, Hett EC, Bloom BR, Glimcher LH, Rubin EJ. Mycobacterium tuberculosis Rv2224c modulates innate immune responses. Proceedings of the National Academy of Sciences of the United States of America. 105: 264-9. PMID 18172199 DOI: 10.1073/Pnas.0710601105  0.671
2007 Glimcher LH, Jones DC, Wein MN. Control of postnatal bone mass by the zinc finger adapter protein Schnurri-3. Annals of the New York Academy of Sciences. 1116: 174-81. PMID 18083927 DOI: 10.1196/Annals.1402.044  0.661
2007 Jones DC, Wein MN, Glimcher LH. Schnurri-3: a key regulator of postnatal skeletal remodeling. Advances in Experimental Medicine and Biology. 602: 1-13. PMID 17966382 DOI: 10.1007/978-0-387-72009-8_1  0.685
2007 Jones DC, Wein MN, Glimcher LH. Schnurri-3 is an essential regulator of osteoblast function and adult bone mass. Annals of the Rheumatic Diseases. 66: iii49-51. PMID 17934096 DOI: 10.1136/Ard.2007.078352  0.669
2007 Garrett WS, Lord GM, Punit S, Lugo-Villarino G, Mazmanian SK, Ito S, Glickman JN, Glimcher LH. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell. 131: 33-45. PMID 17923086 DOI: 10.1016/J.Cell.2007.08.017  0.693
2007 Iwakoshi NN, Pypaert M, Glimcher LH. The transcription factor XBP-1 is essential for the development and survival of dendritic cells. The Journal of Experimental Medicine. 204: 2267-75. PMID 17875675 DOI: 10.1084/Jem.20070525  0.352
2007 Erlebacher A, Vencato D, Price KA, Zhang D, Glimcher LH. Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus. The Journal of Clinical Investigation. 117: 1399-411. PMID 17446933 DOI: 10.1172/Jci28214  0.407
2007 Glimcher LH. Trawling for treasure: tales of T-bet. Nature Immunology. 8: 448-50. PMID 17440449 DOI: 10.1038/Ni0507-448  0.407
2007 Aliprantis AO, Wang J, Fathman JW, Lemaire R, Dorfman DM, Lafyatis R, Glimcher LH. Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13. Proceedings of the National Academy of Sciences of the United States of America. 104: 2827-30. PMID 17307869 DOI: 10.1073/Pnas.0700021104  0.465
2007 Alcaide P, Jones TG, Lord GM, Glimcher LH, Hallgren J, Arinobu Y, Akashi K, Paterson AM, Gurish MA, Luscinskas FW. Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue. The Journal of Experimental Medicine. 204: 431-9. PMID 17296784 DOI: 10.1084/Jem.20060626  0.458
2006 Taqueti VR, Grabie N, Colvin R, Pang H, Jarolim P, Luster AD, Glimcher LH, Lichtman AH. T-bet controls pathogenicity of CTLs in the heart by separable effects on migration and effector activity. Journal of Immunology (Baltimore, Md. : 1950). 177: 5890-901. PMID 17056513 DOI: 10.4049/Jimmunol.177.9.5890  0.437
2006 Martinon F, Glimcher LH. Gout: new insights into an old disease. The Journal of Clinical Investigation. 116: 2073-5. PMID 16886051 DOI: 10.1172/Jci29404  0.309
2006 Rosas LE, Snider HM, Barbi J, Satoskar AA, Lugo-Villarino G, Keiser T, Papenfuss T, Durbin JE, Radzioch D, Glimcher LH, Satoskar AR. Cutting edge: STAT1 and T-bet play distinct roles in determining outcome of visceral leishmaniasis caused by Leishmania donovani. Journal of Immunology (Baltimore, Md. : 1950). 177: 22-5. PMID 16785492 DOI: 10.4049/Jimmunol.177.1.22  0.727
2006 Jones DC, Wein MN, Oukka M, Hofstaetter JG, Glimcher MJ, Glimcher LH. Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. Science (New York, N.Y.). 312: 1223-7. PMID 16728642 DOI: 10.1126/Science.1126313  0.671
2006 Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schrinzel A, Glimcher LH, Korsmeyer SJ. Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1α Science. 312: 572-576. PMID 16645094 DOI: 10.1126/Science.1123480  0.327
2006 Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, Glimcher LH, Cantor H. Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nature Immunology. 7: 498-506. PMID 16604075 DOI: 10.1038/Ni1327  0.354
2006 Wang J, Fathman JW, Lugo-Villarino G, Scimone L, von Andrian U, Dorfman DM, Glimcher LH. Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells. The Journal of Clinical Investigation. 116: 414-21. PMID 16410834 DOI: 10.1172/Jci26631  0.728
2006 Tirosh B, Iwakoshi NN, Glimcher LH, Ploegh HL. Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response Journal of Biological Chemistry. 281: 5852-5860. PMID 16332684 DOI: 10.1074/Jbc.M509061200  0.328
2006 Raby BA, Hwang ES, Van Steen K, Tantisira K, Peng S, Litonjua A, Lazarus R, Giallourakis C, Rioux JD, Sparrow D, Silverman EK, Glimcher LH, Weiss ST. T-bet polymorphisms are associated with asthma and airway hyperresponsiveness. American Journal of Respiratory and Critical Care Medicine. 173: 64-70. PMID 16179640 DOI: 10.1164/Rccm.200503-505Oc  0.377
2005 Lee AH, Chu GC, Iwakoshi NN, Glimcher LH. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. The Embo Journal. 24: 4368-80. PMID 16362047 DOI: 10.1038/Sj.Emboj.7600903  0.346
2005 Wein MN, Jones DC, Glimcher LH. Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity. Immunological Reviews. 208: 66-79. PMID 16313341 DOI: 10.1111/J.0105-2896.2005.00322.X  0.722
2005 Shinohara ML, Jansson M, Hwang ES, Werneck MB, Glimcher LH, Cantor H. T-bet-dependent expression of osteopontin contributes to T cell polarization. Proceedings of the National Academy of Sciences of the United States of America. 102: 17101-6. PMID 16286640 DOI: 10.1073/Pnas.0508666102  0.483
2005 Eun SH, Hong JH, Glimcher LH. IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508 Journal of Experimental Medicine. 202: 1289-1300. PMID 16275766 DOI: 10.1084/Jem.20051044  0.416
2005 Ravindran R, Foley J, Stoklasek T, Glimcher LH, McSorley SJ. Expression of T-bet by CD4 T cells is essential for resistance to Salmonella infection. Journal of Immunology (Baltimore, Md. : 1950). 175: 4603-10. PMID 16177105 DOI: 10.4049/Jimmunol.175.7.4603  0.459
2005 Sullivan BM, Jobe O, Lazarevic V, Vasquez K, Bronson R, Glimcher LH, Kramnik I. Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production. Journal of Immunology (Baltimore, Md. : 1950). 175: 4593-602. PMID 16177104 DOI: 10.4049/Jimmunol.175.7.4593  0.419
2005 Lugo-Villarino G, Ito S, Klinman DM, Glimcher LH. The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 13248-53. PMID 16135562 DOI: 10.1073/Pnas.0506638102  0.719
2005 Tirosh B, Iwakoshi NN, Glimcher LH, Ploegh HL. XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells Journal of Experimental Medicine. 202: 505-516. PMID 16103408 DOI: 10.1084/Jem.20050575  0.361
2005 Lord GM, Rao RM, Choe H, Sullivan BM, Lichtman AH, Luscinskas FW, Glimcher LH. T-bet is required for optimal proinflammatory CD4+ T-cell trafficking. Blood. 106: 3432-9. PMID 16014561 DOI: 10.1182/Blood-2005-04-1393  0.427
2005 Finotto S, Hausding M, Doganci A, Maxeiner JH, Lehr HA, Luft C, Galle PR, Glimcher LH. Asthmatic changes in mice lacking T-bet are mediated by IL-13. International Immunology. 17: 993-1007. PMID 16000330 DOI: 10.1093/Intimm/Dxh281  0.392
2005 Dorfman DM, Hwang ES, Shahsafaei A, Glimcher LH. T-bet, a T cell-associated transcription factor, is expressed in Hodgkin's lymphoma Human Pathology. 36: 10-15. PMID 15712176 DOI: 10.1016/J.Humpath.2004.10.006  0.405
2005 Tirosh B, Iwakoshi NN, Lilley BN, Lee AH, Glimcher LH, Ploegh HL. Human cytomegalovirus protein US11 provokes an unfolded protein response that may facilitate the degradation of class I major histocompatibility complex products. Journal of Virology. 79: 2768-79. PMID 15708995 DOI: 10.1128/Jvi.79.5.2768-2779.2005  0.356
2005 Buono C, Binder CJ, Stavrakis G, Witztum JL, Glimcher LH, Lichtman AH. T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses. Proceedings of the National Academy of Sciences of the United States of America. 102: 1596-601. PMID 15665085 DOI: 10.1073/Pnas.0409015102  0.456
2005 Hwang ES, Szabo SJ, Schwartzberg PL, Glimcher LH. T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science (New York, N.Y.). 307: 430-3. PMID 15662016 DOI: 10.1126/Science.1103336  0.454
2005 Rao R, Lord G, Choe H, Lichtman A, Luscinskas F, Glimcher LH. The transcription T-bet is required for optimal proinflammatory trafficking of CD4+ T cells Arthritis Research & Therapy. 7: 5. DOI: 10.1186/Ar1526  0.447
2004 Tantisira KG, Hwang ES, Raby BA, Silverman ES, Lake SL, Richter BG, Peng SL, Drazen JM, Glimcher LH, Weiss ST. TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids. Proceedings of the National Academy of Sciences of the United States of America. 101: 18099-104. PMID 15604153 DOI: 10.1073/Pnas.0408532102  0.327
2004 Mowen KA, Glimcher LH. Signaling pathways in Th2 development. Immunological Reviews. 202: 203-22. PMID 15546395 DOI: 10.1111/J.0105-2896.2004.00209.X  0.366
2004 Glimcher LH, Townsend MJ, Sullivan BM, Lord GM. Recent developments in the transcriptional regulation of cytolytic effector cells Nature Reviews Immunology. 4: 900-911. PMID 15516969 DOI: 10.1038/Nri1490  0.461
2004 Maldonade RA, Irvine DJ, Schreiber R, Glimcher LH. A role for the immunological synapse in lineage commitment of CD4 lymphocytes Nature. 431: 527-532. PMID 15386021 DOI: 10.1038/Nature02916  0.401
2004 Shaffer AL, Shapiro-Shelef M, Iwakoshi NN, Lee AH, Qian SB, Zhao H, Yu X, Yang L, Tan BK, Rosenwald A, Hurt EM, Petroulakis E, Sonenberg N, Yewdell JW, Calame K, ... Glimcher LH, et al. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity. 21: 81-93. PMID 15345222 DOI: 10.1016/J.Immuni.2004.06.010  0.392
2004 Romero-Ramirez L, Cao H, Nelson D, Hammond E, Lee AH, Yoshida H, Mori K, Glimcher LH, Denko NC, Giaccia AJ, Le QT, Koong AC. XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Cancer Research. 64: 5943-7. PMID 15342372 DOI: 10.1158/0008-5472.Can-04-1606  0.326
2004 Mowen KA, Schurter BT, Fathman JW, David M, Glimcher LH. Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes. Molecular Cell. 15: 559-71. PMID 15327772 DOI: 10.1016/J.Molcel.2004.06.042  0.457
2004 Dorfman DM, Hwang ES, Shahsafaei A, Glimcher LH. T-bet, a T-cell-associated transcription factor, is expressed in a subset of B-cell lymphoproliferative disorders American Journal of Clinical Pathology. 122: 292-297. PMID 15323146 DOI: 10.1309/Aqq2Dvm75Dvy0Pwp  0.42
2004 Bettelli E, Sullivan B, Szabo SJ, Sobel RA, Glimcher LH, Kuchroo VK. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 200: 79-87. PMID 15238607 DOI: 10.1084/Jem.20031819  0.479
2004 Lametschwandtner G, Biedermann T, Schwärzler C, Günther C, Kund J, Fassl S, Hinteregger S, Carballido-Perrig N, Szabo SJ, Glimcher LH, Carballido JM. Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities. The Journal of Allergy and Clinical Immunology. 113: 987-94. PMID 15131585 DOI: 10.1016/J.Jaci.2004.02.004  0.41
2004 Juedes AE, Rodrigo E, Togher L, Glimcher LH, von Herrath MG. T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes. The Journal of Experimental Medicine. 199: 1153-62. PMID 15096540 DOI: 10.1084/Jem.20031873  0.381
2004 Townsend MJ, Weinmann AS, Matsuda JL, Salomon R, Farnham PJ, Biron CA, Gapin L, Glimcher LH. T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity. 20: 477-94. PMID 15084276 DOI: 10.1016/S1074-7613(04)00076-7  0.465
2004 Gerth AJ, Lin L, Neurath MF, Glimcher LH, Peng SL. An Innate Cell-Mediated, Murine Ulcerative Colitis-like Syndrome in the Absence of Nuclear Factor of Activated T Cells Gastroenterology. 126: 1115-1121. PMID 15057750 DOI: 10.1053/J.Gastro.2004.01.013  0.472
2004 Peng SL, Townsend MJ, Hecht JL, White IA, Glimcher LH. T-bet regulates metastasis rate in a murine model of primary prostate cancer. Cancer Research. 64: 452-5. PMID 14744755 DOI: 10.1158/0008-5472.Can-03-3401  0.4
2004 Oukka M, Wein MN, Glimcher LH. Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells. The Journal of Experimental Medicine. 199: 15-24. PMID 14707112 DOI: 10.1084/Jem.20030421  0.734
2004 Weigmann B, Nemetz A, Becker C, Lehr H, Glimcher L, Galle P, Neurath M. Eine regulatorische Rolle des Transkriptionsfaktors c-Maf in der T-Zell abhängigen experimentellen Colitis Zeitschrift Fur Gastroenterologie. 42. DOI: 10.1055/S-2004-831530  0.306
2004 Kawana K, Kawana Y, Ashby R, Patel R, Glimcher L, Schust D. T-bet, a key transcriptional factor for Th1 development, is expressed and regulated via Stat family in the epithelial cells of the reproductive tract Fertility and Sterility. 82: S59. DOI: 10.1016/j.fertnstert.2004.07.151  0.309
2003 Finotto S, Glimcher L. T cell directives for transcriptional regulation in asthma. Springer Seminars in Immunopathology. 25: 281-94. PMID 15007632 DOI: 10.1007/S00281-003-0143-1  0.486
2003 Melanitou E, Liu E, Miao D, Yu L, Glimcher LH, Eisenbarth G. Absence of the T-bet gene coding for the Th1-related transcription factor does not affect diabetes-associated phenotypes in Balb/c mice. Annals of the New York Academy of Sciences. 1005: 187-91. PMID 14679057 DOI: 10.1196/Annals.1288.024  0.439
2003 Sullivan BM, Juedes A, Szabo SJ, von Herrath M, Glimcher LH. Antigen-driven effector CD8 T cell function regulated by T-bet. Proceedings of the National Academy of Sciences of the United States of America. 100: 15818-23. PMID 14673093 DOI: 10.1073/Pnas.2636938100  0.454
2003 Pai SY, Truitt ML, Ting CN, Leiden JM, Glimcher LH, Ho IC. Critical roles for transcription factor GATA-3 in thymocyte development. Immunity. 19: 863-75. PMID 14670303 DOI: 10.1016/S1074-7613(03)00328-5  0.383
2003 Iwakoshi NN, Lee AH, Glimcher LH. It's a good year for Blimp-1 (and plasma cells) Immunity. 19: 466-468. PMID 14563311 DOI: 10.1016/S1074-7613(03)00274-7  0.335
2003 Lee AH, Iwakoshi NN, Glimcher LH. XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response Molecular and Cellular Biology. 23: 7448-7459. PMID 14559994 DOI: 10.1128/Mcb.23.21.7448-7459.2003  0.362
2003 MacLean HE, Kim JI, Glimcher MJ, Wang J, Kronenberg HM, Glimcher LH. Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development Developmental Biology. 262: 51-63. PMID 14512017 DOI: 10.1016/S0012-1606(03)00324-5  0.301
2003 Lee AH, Iwakoshi NN, Anderson KC, Glimcher LH. Proteasome inhibitors disrupt the unfolded protein response in myeloma cells Proceedings of the National Academy of Sciences of the United States of America. 100: 9946-9951. PMID 12902539 DOI: 10.1073/Pnas.1334037100  0.362
2003 Iwakoshi NN, Lee AH, Glimcher LH. The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response Immunological Reviews. 194: 29-38. PMID 12846805 DOI: 10.1034/J.1600-065X.2003.00057.X  0.356
2003 Lugo-Villarino G, Maldonado-Lopez R, Possemato R, Penaranda C, Glimcher LH. T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 7749-54. PMID 12802010 DOI: 10.1073/Pnas.1332767100  0.729
2003 Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, Glimcher LH. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-I Nature Immunology. 4: 321-329. PMID 12612580 DOI: 10.1038/Ni907  0.366
2003 Szabo SJ, Sullivan BM, Peng SL, Glimcher LH. Molecular mechanisms regulating Th1 immune responses Annual Review of Immunology. 21: 713-758. PMID 12500979 DOI: 10.1146/Annurev.Immunol.21.120601.140942  0.405
2003 Paul WE, Fathman CG, Glimcher LH. Annual review of immunology, vol. 20, 2002 Revista Do Instituto De Medicina Tropical De SãO Paulo. 45: 57-58. DOI: 10.1590/S0036-46652003000100018  0.399
2003 Dorfman DM, van den Elzen P, Weng AP, Shahsafaei A, Glimcher LH. Differential Expression of T-bet, a T-box Transcription Factor Required for Th1 T-Cell Development, in Peripheral T-Cell Lymphomas American Journal of Clinical Pathology. 120: 866-873. DOI: 10.1309/J3Ctlttjevuy4Yl0  0.404
2002 Erlebacher A, Lukens AK, Glimcher LH. Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo. Proceedings of the National Academy of Sciences of the United States of America. 99: 16940-5. PMID 12486249 DOI: 10.1073/Pnas.222652199  0.354
2002 Avni O, Lee D, Macian F, Szabo SJ, Glimcher LH, Rao A. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nature Immunology. 3: 643-51. PMID 12055628 DOI: 10.1038/Ni808  0.438
2002 Neurath MF, Finotto S, Glimcher LH. The role of TH1/TH2 polarization in mucosal immunity Nature Medicine. 8: 567-573. PMID 12042806 DOI: 10.1038/Nm0602-567  0.359
2002 Neurath MF, Weigmann B, Finotto S, Glickman J, Nieuwenhuis E, Iijima H, Mizoguchi A, Mizoguchi E, Mudter J, Galle PR, Bhan A, Autschbach F, Sullivan BM, Szabo SJ, Glimcher LH, et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease Journal of Experimental Medicine. 195: 1129-1143. PMID 11994418 DOI: 10.1084/Jem.20011956  0.447
2002 Ho IC, Glimcher LH. Transcription: Tantalizing times for T cells Cell. 109. PMID 11983157 DOI: 10.1016/S0092-8674(02)00705-5  0.423
2002 Peng SL, Szabo SJ, Glimcher LH. T-bet regulates IgG class switching and pathogenic autoantibody production Proceedings of the National Academy of Sciences of the United States of America. 99: 5545-5550. PMID 11960012 DOI: 10.1073/Pnas.082114899  0.478
2002 Rengarajan J, Mowen KA, McBride KD, Smith ED, Singh H, Glimcher LH. Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. The Journal of Experimental Medicine. 195: 1003-12. PMID 11956291 DOI: 10.1084/Jem.20011128  0.724
2002 Yin Z, Chen C, Szabo SJ, Glimcher LH, Ray A, Craft J. T-Bet expression and failure of GATA-3 cross-regulation lead to default production of IFN-gamma by gammadelta T cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 1566-71. PMID 11823483 DOI: 10.4049/Jimmunol.168.4.1566  0.445
2002 Oukka M, Kim ST, Lugo G, Sun J, Wu LC, Glimcher LH. A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2. Molecular Cell. 9: 121-31. PMID 11804591 DOI: 10.1016/S1097-2765(01)00434-8  0.352
2002 Szabo SJ, Sullivan BM, Stemmann C, Satoskar AR, Sleckman BP, Glimcher LH. Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science (New York, N.Y.). 295: 338-42. PMID 11786644 DOI: 10.1126/Science.1065543  0.425
2002 Finotto S, Neurath MF, Glickman JN, Qin S, Lehr HA, Green FH, Ackerman K, Haley K, Galle PR, Szabo SJ, Drazen JM, De Sanctis GT, Glimcher LH. Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science (New York, N.Y.). 295: 336-8. PMID 11786643 DOI: 10.1126/Science.1065544  0.379
2002 Rengarajan J, Tang B, Glimcher LH. NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells. Nature Immunology. 3: 48-54. PMID 11740499 DOI: 10.1038/Ni744  0.741
2001 Reimold AM, Iwakoshi NN, Manis J, Vallabhajosyula P, Szomolanyi-Tsuda E, Gravallese EM, Friend D, Grusby MJ, Alt F, Glimcher LH. Plasma cell differentiation requires the transcription factor XBP-1. Nature. 412: 300-7. PMID 11460154 DOI: 10.1038/35085509  0.362
2001 Lieberson R, Mowen KA, McBride KD, Leautaud V, Zhang X, Suh WK, Wu L, Glimcher LH. Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45) Journal of Experimental Medicine. 194: 89-98. PMID 11435475 DOI: 10.1084/Jem.194.1.89  0.426
2001 Ho IC, Arm JP, Bingham CO, Choi A, Austen KF, Glimcher LH. A novel group of phospholipase A2s preferentially expressed in type 2 helper T cells. The Journal of Biological Chemistry. 276: 18321-6. PMID 11278438 DOI: 10.1074/Jbc.M008837200  0.412
2001 Peng SL, Gerth AJ, Ranger AM, Glimcher LH. NFATc1 and NFATc2 together control both T and B cell activation and differentiation Immunity. 14: 13-20. PMID 11163226 DOI: 10.1016/S1074-7613(01)00085-1  0.487
2001 Reimold AM, Kim J, Finberg R, Glimcher LH. Decreased immediate inflammatory gene induction in activating transcription factor-2 mutant mice International Immunology. 13: 241-248. PMID 11157857 DOI: 10.1093/Intimm/13.2.241  0.397
2001 Pauza ME, Nguyen A, Wolfe T, Ho IC, Glimcher LH, Von Herrath M, Lo D. Variable effects of transgenic c-Maf on autoimmune diabetes Diabetes. 50: 39-46. PMID 11147792 DOI: 10.2337/Diabetes.50.1.39  0.416
2000 Rengarajan J, Szabo SJ, Glimcher LH. Transcriptional regulation of Th1/Th2 polarization. Immunology Today. 21: 479-83. PMID 11071525 DOI: 10.1016/S0167-5699(00)01712-6  0.689
2000 Glimcher LH, Murphy KM. Lineage commitment in the immune system: the T helper lymphocyte grows up. Genes & Development. 14: 1693-711. PMID 10898785 DOI: 10.1101/Gad.14.14.1693  0.478
2000 Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 100: 655-69. PMID 10761931 DOI: 10.1016/S0092-8674(00)80702-3  0.439
2000 Rengarajan J, Mittelstadt PR, Mages HW, Gerth AJ, Kroczek RA, Ashwell JD, Glimcher LH. Sequential involvement of NFAT and Egr transcription factors in FasL regulation. Immunity. 12: 293-300. PMID 10755616 DOI: 10.1016/S1074-7613(00)80182-X  0.725
2000 Reimold AM, Etkin A, Clauss I, Perkins A, Friend DS, Zhang J, Horton HF, Scott A, Orkin SH, Byrne MC, Grusby MJ, Glimcher LH. An essential role in liver development for transcription factor XBP-1. Genes & Development. 14: 152-7. PMID 10652269 DOI: 10.1101/Gad.14.2.152  0.319
2000 Ranger AM, Gerstenfeld LC, Wang J, Kon T, Bae H, Gravallese EM, Glimcher MJ, Glimcher LH. The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis Journal of Experimental Medicine. 191: 9-21. PMID 10620601 DOI: 10.1084/Jem.191.1.9  0.434
1999 Ho IC, Kim JI, Szabo SJ, Glimcher LH. Tissue-specific regulation of cytokine gene expression Cold Spring Harbor Symposia On Quantitative Biology. 64: 573-584. PMID 11232334 DOI: 10.1101/Sqb.1999.64.573  0.315
1999 de Bont ES, Reilly CR, Lo D, Glimcher LH, Laufer TM. A minimal level of MHC class II expression is sufficient to abrogate autoreactivity. International Immunology. 11: 1295-306. PMID 10421787 DOI: 10.1093/Intimm/11.8.1295  0.396
1999 Kim JI, Ho IC, Grusby MJ, Glimcher LH. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines Immunity. 10: 745-751. PMID 10403649 DOI: 10.1016/S1074-7613(00)80073-4  0.409
1999 Wen XY, Stewart AK, Sooknanan RR, Henderson G, Hawley T, Reimold AM, Glimcher LH, Baumann H, Malek LT, Hawley RG. Identification of c-myc promoter-binding protein and X-box binding protein 1 as interleukin-6 target genesin human multiple myeloma cells International Journal of Oncology. 15: 173-178. PMID 10375612 DOI: 10.3892/Ijo.15.1.173  0.397
1999 Maekawa T, Bernier F, Sato M, Nomura S, Singh M, Inoue Y, Tokunaga T, Imai H, Yokoyama M, Reimold A, Glimcher LH, Ishii S. Mouse ATF-2 null mutants display features of a severe type of meconium aspiration syndrome. The Journal of Biological Chemistry. 274: 17813-9. PMID 10364225 DOI: 10.1074/Jbc.274.25.17813  0.32
1999 Laufer TM, Fan L, Glimcher LH. Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo Journal of Immunology. 162: 5078-5084. PMID 10227976  0.301
1999 Kim JI, Li T, Ho IC, Grusby MJ, Glimcher LH. Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development Proceedings of the National Academy of Sciences of the United States of America. 96: 3781-3785. PMID 10097114 DOI: 10.1073/Pnas.96.7.3781  0.358
1999 Ho IC, Kaplan MH, Jackson-Grusby L, Glimcher LH, Grusby MJ. Marking IL-4-producing cells by knock-in of the IL-4 gene. International Immunology. 11: 243-7. PMID 10069422 DOI: 10.1093/Intimm/11.2.243  0.387
1999 Glimcher LH, Singh H. Transcription factors in lymphocyte development - T and B cells get together Cell. 96: 13-23. PMID 9989493 DOI: 10.1016/S0092-8674(00)80955-1  0.375
1999 Laufer TM, Glimcher LH, Lo D. Using thymus anatomy to dissect T cell repertoire selection Seminars in Immunology. 11: 65-70. PMID 9950753 DOI: 10.1006/Smim.1998.9997  0.394
1999 Ho IC, Kim JH, Rooney JW, Spiegelman BM, Glimcher LH. A potential role for the nuclear factor of activated T cells family of transcriptional regulatory proteins in adipogenesis. Proceedings of the National Academy of Sciences of the United States of America. 95: 15537-41. PMID 9861004 DOI: 10.1073/Pnas.95.26.15537  0.46
1998 Ranger AM, Oukka M, Rengarajan J, Glimcher LH. Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. Immunity. 9: 627-35. PMID 9846484 DOI: 10.1016/S1074-7613(00)80660-3  0.727
1998 Ho IC, Lo D, Glimcher LH. c-maf Promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms Journal of Experimental Medicine. 188: 1859-1866. PMID 9815263 DOI: 10.1084/Jem.188.10.1859  0.375
1998 Oukka M, Ho IC, de la Brousse FC, Hoey T, Grusby MJ, Glimcher LH. The transcription factor NFAT4 is involved in the generation and survival of T cells. Immunity. 9: 295-304. PMID 9768749 DOI: 10.1016/S1074-7613(00)80612-3  0.485
1998 Ranger AM, Grusby MJ, Hodge MR, Gravallese EM, de la Brousse FC, Hoey T, Mickanin C, Baldwin HS, Glimcher LH. The transcription factor NF-ATc is essential for cardiac valve formation. Nature. 392: 186-90. PMID 9515964 DOI: 10.1038/32426  0.347
1998 Ranger AM, Hodge MR, Gravallese EM, Oukka M, Davidson L, Alt FW, de la Brousse FC, Hoey T, Grusby M, Glimcher LH. Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc. Immunity. 8: 125-34. PMID 9462518 DOI: 10.1016/S1074-7613(00)80465-3  0.407
1997 Szabo SJ, Glimcher LH, Ho IC. Genes that regulate interleukin-4 expression in T cells Current Opinion in Immunology. 9: 776-781. PMID 9492977 DOI: 10.1016/S0952-7915(97)80177-X  0.457
1997 Douhan J, Lieberson R, Knoll JHM, Zhou H, Glimcher LH. An isotype-specific activator of major histocompatibility complex (MHC) class II genes that is independent of class II transactivator Journal of Experimental Medicine. 185: 1885-1895. PMID 9166418 DOI: 10.1084/Jem.185.11.1885  0.336
1997 Lee RS, Grusby MJ, Laufer TM, Colvin R, Glimcher LH, Auchincloss H. CD8+ effector cells responding to residual class I antigens, with help from CD4+ cells stimulated indirectly, cause rejection of "major histocompatibility complex-deficient" skin grafts. Transplantation. 63: 1123-33. PMID 9133474 DOI: 10.1097/00007890-199704270-00012  0.335
1997 Lo D, Reilly CR, Burkly LC, DeKoning J, Laufer TM, Glimcher LH. Thymic stromal cell specialization and the T-cell receptor repertoire. Immunologic Research. 16: 3-14. PMID 9048205 DOI: 10.1007/Bf02786320  0.426
1996 Hodge MR, Chun HJ, Rengarajan J, Alt A, Lieberson R, Glimcher LH. NF-AT-Driven interleukin-4 transcription potentiated by NIP45. Science (New York, N.Y.). 274: 1903-5. PMID 8943202 DOI: 10.1126/Science.274.5294.1903  0.703
1996 Brown JA, Titus RG, Nabavi N, Glimcher LH. Blockade of CD86 ameliorates Leishmania major infection by down- regulating the Th2 response Journal of Infectious Diseases. 174: 1303-1308. PMID 8940222 DOI: 10.1093/Infdis/174.6.1303  0.306
1996 Ranger AM, Das MP, Kuchroo VK, Glimcher LH. B7-2 (CD86) is essential for the development of IL-4-producing T cells International Immunology. 8: 1549-1560. PMID 8921434 DOI: 10.1093/Intimm/8.10.1549  0.397
1996 Laufer TM, DeKoning J, Markowitz JS, Lo D, Glimcher LH. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex Nature. 383: 81-85. PMID 8779719 DOI: 10.1038/383081A0  0.42
1996 Ho IC, Hodge MR, Rooney JW, Glimcher LH. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4 Cell. 85: 973-983. PMID 8674125 DOI: 10.1016/S0092-8674(00)81299-4  0.406
1996 Douhan J, Brown JA, Gleit ZL, David CS, Glimcher LH. Regulation of the Eβ gene in vivo: Lessons from Eβd transgenic mice International Immunology. 8: 255-265. PMID 8671611 DOI: 10.1093/Intimm/8.2.255  0.395
1996 Tarleton RL, Grusby MJ, Postan M, Glimcher LH. Trypanosoma cruzi infection in MHC-deficient mice: Further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease International Immunology. 8: 13-22. PMID 8671585 DOI: 10.1093/Intimm/8.1.13  0.39
1996 Clauss IM, Chu M, Zhao JL, Glimcher LH. The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core Nucleic Acids Research. 24: 1855-1864. PMID 8657566 DOI: 10.1093/Nar/24.10.1855  0.35
1996 Zhao JL, Freeman GJ, Gray GS, Nadler LM, Glimcher LH. A cell type-specific enhancer in the human B7.1 gene regulated by NF-κB Journal of Experimental Medicine. 183: 777-789. PMID 8642282 DOI: 10.1084/Jem.183.3.777  0.394
1996 Douhan J, Hauber I, Eibl MM, Glimcher LH. Genetic evidence for a new type of major histocompatibility complex class II combined immunodeficiency characterized by a dyscoordinate regulation of HLA-D alpha and beta chains. The Journal of Experimental Medicine. 183: 1063-9. PMID 8642248 DOI: 10.1084/Jem.183.3.1063  0.33
1996 Steele DJ, Laufer TM, Smiley ST, Ando Y, Grusby MJ, Glimcher LH, Auchincloss H. Two levels of help for B cell alloantibody production. The Journal of Experimental Medicine. 183: 699-703. PMID 8627185 DOI: 10.1084/Jem.183.2.699  0.369
1996 Reimold AM, Ponath PD, Li YS, Hardy RR, David CS, Strominger JL, Glimcher LH. Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1 Journal of Experimental Medicine. 183: 393-401. PMID 8627152 DOI: 10.1084/Jem.183.2.393  0.382
1996 Hodge MR, Ranger AM, Charles de la Brousse F, Hoey T, Grusby MJ, Glimcher LH. Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice. Immunity. 4: 397-405. PMID 8612134 DOI: 10.1016/S1074-7613(00)80253-8  0.411
1996 Smiley ST, Rudensky AY, Glimcher LH, Grusby MJ. Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes. Proceedings of the National Academy of Sciences of the United States of America. 93: 241-4. PMID 8552613 DOI: 10.1073/Pnas.93.1.241  0.332
1996 Reimold AM, Grusby MJ, Kosaras B, Fries JW, Mori R, Maniwa S, Clauss IM, Collins T, Sidman RL, Glimcher MJ, Glimcher LH. Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice. Nature. 379: 262-5. PMID 8538792 DOI: 10.1038/379262A0  0.351
1995 Linette GP, Grusby MJ, Hedrick SM, Hansen TH, Glimcher LH, Korsmeyer SJ. Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points. Immunity. 1: 197-205. PMID 7889408 DOI: 10.1016/1074-7613(94)90098-1  0.593
1995 Ruderman EM, Kerr JS, Telford SR, Spielman A, Glimcher LH, Gravallese EM. Early murine Lyme carditis has a macrophage predominance and is independent of major histocompatibility complex class II-CD4+ T cell interactions. The Journal of Infectious Diseases. 171: 362-70. PMID 7844373 DOI: 10.1093/Infdis/171.2.362  0.372
1995 Baskar S, Glimcher L, Nabavi N, Jones RT, Ostrand-Rosenberg S. Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice. The Journal of Experimental Medicine. 181: 619-29. PMID 7836917 DOI: 10.1084/Jem.181.2.619  0.36
1995 Chakkalath HR, Theodos CM, Markowitz JS, Grusby MJ, Glimcher LH, Titus RG. Class II major histocompatibility complex-deficient mice initially control an infection with leishmania major but succumb to the disease Journal of Infectious Diseases. 171: 1302-1308. PMID 7751707 DOI: 10.1093/Infdis/171.5.1302  0.353
1995 Zhou H, Glimcher LH. Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency Immunity. 2: 545-553. PMID 7749985 DOI: 10.1016/1074-7613(95)90034-9  0.351
1995 Rooney JW, Hoey T, Glimcher LH. Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene. Immunity. 2: 473-83. PMID 7749982 DOI: 10.1016/1074-7613(95)90028-4  0.345
1995 Grusby MJ, Glimcher LH. Immune responses in MHC class II-deficient mice Annual Review of Immunology. 13: 417-435. PMID 7612230 DOI: 10.1146/Annurev.Iy.13.040195.002221  0.394
1995 Rooney JW, Sun YL, Glimcher LH, Hoey T. Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation. Molecular and Cellular Biology. 15: 6299-310. PMID 7565783 DOI: 10.1128/Mcb.15.11.6299  0.379
1995 Smiley ST, Laufer TM, Lo D, Glimcher LH, Grusby MJ. Transgenic mice expressing MHC class II molecules with truncated A beta cytoplasmic domains reveal signaling-independent defects in antigen presentation. International Immunology. 7: 665-77. PMID 7547694 DOI: 10.1093/Intimm/7.4.665  0.433
1995 Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell. 80: 707-18. PMID 7534215 DOI: 10.1016/0092-8674(95)90349-6  0.349
1994 Rooney JW, Hodge MR, McCaffrey PG, Rao A, Glimcher LH. A common factor regulates both Th1- and Th2-specific cytokine gene expression Embo Journal. 13: 625-633. PMID 8313907 DOI: 10.1002/J.1460-2075.1994.Tb06300.X  0.393
1994 Ivashkiv LB, Ayres A, Glimcher LH. Inhibition of IFN-γ induction of class II MHC genes by cAMP and prostaglandins Immunopharmacology. 27: 67-77. PMID 8206755 DOI: 10.1016/0162-3109(94)90008-6  0.333
1994 Lee RS, Grusby MJ, Glimcher LH, Winn HJ, Auchincloss H. Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo Journal of Experimental Medicine. 179: 865-872. PMID 8113680 DOI: 10.1084/Jem.179.3.865  0.382
1994 Matsushima GK, Taniike M, Glimcher LH, Grusby MJ, Frelinger JA, Suzuki K, Ting JP. Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy. Cell. 78: 645-56. PMID 8069913 DOI: 10.1016/0092-8674(94)90529-0  0.408
1994 Darling JM, Glimcher LH, Shortkroff S, Albano B, Gravallese EM. Expression of metalloproteinases in pigmented villonodular synovitis. Human Pathology. 25: 825-30. PMID 8056425 DOI: 10.1016/0046-8177(94)90254-2  0.335
1994 Avery AC, Markowitz JS, Grusby MJ, Glimcher LH, Cantor H. Activation of T cells by superantigen in class II-negative mice Journal of Immunology. 153: 4853-4861. PMID 7963549  0.341
1994 Jevnikar AM, Grusby MJ, Glimcher LH. Prevention of nephritis in major histocompatibility complex class II-deficient MRL-1pr mice Journal of Experimental Medicine. 179: 1137-1143. PMID 7908320 DOI: 10.1084/Jem.179.4.1137  0.393
1994 Degermann S, Surh CD, Glimcher LH, Sprent J, Lo D. B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of Vβ5+ thymocytes Journal of Immunology. 152: 3254-3263. PMID 7511640  0.329
1993 Todd MD, Grusby MJ, Lederer JA, Lacy E, Lichtman AH, Glimcher LH. Transcription of the interleukin 4 gene is regulated by multiple promoter elements. The Journal of Experimental Medicine. 177: 1663-74. PMID 8496684 DOI: 10.1084/Jem.177.6.1663  0.362
1993 Cantor H, Crump AL, Raman VK, Liu H, Markowitz JS, Grusby MJ, Glimcher LH. Immunoregulatory effects of superantigens: interactions of staphylococcal enterotoxins with host MHC and non-MHC products. Immunological Reviews. 131: 27-42. PMID 8486393 DOI: 10.1111/J.1600-065X.1993.Tb01528.X  0.397
1993 Grusby MJ, Auchincloss H, Lee R, Johnson RS, Spencer JP, Zijlstra M, Jaenisch R, Papaioannou VE, Glimcher LH. Mice lacking major histocompatibility complex class I and class II molecules. Proceedings of the National Academy of Sciences of the United States of America. 90: 3913-7. PMID 8483910 DOI: 10.1073/Pnas.90.9.3913  0.391
1993 Auchincloss H, Lee R, Shea S, Markowitz JS, Grusby MJ, Glimcher LH. The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 3373-7. PMID 8475083 DOI: 10.1073/Pnas.90.8.3373  0.328
1993 Markowitz JS, Auchincloss H, Grusby MJ, Glimcher LH. Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice Proceedings of the National Academy of Sciences of the United States of America. 90: 2779-2783. PMID 8464889 DOI: 10.1073/Pnas.90.7.2779  0.423
1993 Kara CJ, Glimcher LH. Promoter accessibility within the environment of the MHC is affected in class II-deficient combined immunodeficiency Embo Journal. 12: 187-193. PMID 8428578 DOI: 10.1002/J.1460-2075.1993.Tb05644.X  0.344
1993 Kara CJ, Glimcher LH. Three in vivo promoter phenotypes in MHC class II deficient combined immunodeficiency Immunogenetics. 37: 227-230. PMID 8420831 DOI: 10.1007/Bf00191890  0.35
1993 Baskar S, Nabavi N, Glimcher LH, Ostrand-Rosenberg S. Tumor cells expressing major histocompatibility complex class II and B7 activation molecules stimulate potent tumor-specific immunity Journal of Immunotherapy. 14: 209-215. PMID 8297902 DOI: 10.1097/00002371-199310000-00007  0.401
1993 Mombaerts P, Mizoguchi E, Grusby MJ, Glimcher LH, Bhan AK, Tonegawa S. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell. 75: 274-82. PMID 8104709 DOI: 10.1016/0092-8674(93)80069-Q  0.403
1993 Laufer TM, von Herrath MG, Grusby MJ, Oldstone MB, Glimcher LH. Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient mice. The Journal of Experimental Medicine. 178: 589-96. PMID 8101862 DOI: 10.1084/Jem.178.2.589  0.373
1993 Crump AL, Grusby MJ, Glimcher LH, Cantor H. Thymocyte development in major histocompatibility complex-deficient mice: Evidence for stochastic commitment to the CD4 and CD8 lineages Proceedings of the National Academy of Sciences of the United States of America. 90: 10739-10743. PMID 7902569 DOI: 10.1073/Pnas.90.22.10739  0.361
1993 Clauss IM, Gravallese EM, Darling JM, Shapiro F, Glimcher MJ, Glimcher LH. In situ hybridization studies suggest a role for the basic region-leucine zipper protein hXBP-1 in exocrine gland and skeletal development during mouse embryogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 197: 146-56. PMID 7693055 DOI: 10.1002/Aja.1001970207  0.358
1993 Baskar S, Ostrand-Rosenberg S, Nabavi N, Nadler LM, Freeman GJ, Glimcher LH. Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules Proceedings of the National Academy of Sciences of the United States of America. 90: 5687-5690. PMID 7685909 DOI: 10.1073/Pnas.90.12.5687  0.412
1992 Glimcher LH, Kara CJ. Sequences and factors: A guide to MHC class-II transcription Annual Review of Immunology. 10: 13-49. PMID 1590984 DOI: 10.1146/Annurev.Iy.10.040192.000305  0.368
1992 Hong SC, Chelouche A, Lin RH, Shaywitz D, Braunstein NS, Glimcher L, Janeway CA. An MHC interaction site maps to the amino-terminal half of the T cell receptor alpha chain variable domain. Cell. 69: 999-1009. PMID 1318787 DOI: 10.1016/0092-8674(92)90618-M  0.528
1992 Nabavi N, Freeman GJ, Gault A, Godfrey D, Nadler LM, Glimcher LH. Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression Nature. 360: 266-268. PMID 1279442 DOI: 10.1038/360266A0  0.355
1991 Catherine CJ, Glimcher LH. Regulation of MHC class 11 gene transcription Current Opinion in Immunology. 3: 16-21. PMID 2054109 DOI: 10.1016/0952-7915(91)90070-H  0.327
1991 Li SC, Rothman P, Boothby M, Ferrier P, Glimcher L, Alt FW. Control of immunoglobulin heavy chain constant region gene expression. Advances in Experimental Medicine and Biology. 292: 245-51. PMID 1950776 DOI: 10.1007/978-1-4684-5943-2_27  0.328
1991 Jevnikar AM, Brennan DC, Singer GG, Heng JE, Maslinski W, Wuthrich RP, Glimcher LH, Kelley VE. Stimulated kidney tubular epithelial cells express membrane associated and secreted TNF alpha. Kidney International. 40: 203-11. PMID 1942768 DOI: 10.1038/Ki.1991.201  0.35
1991 Whitley MZ, Sisk R, Ivashkiv LB, Finn PW, Glimcher LH, Boothby MR. Non-consensus DNA sequences function in a cell-type-specific enhancer of the mouse class II MHC gene A alpha. International Immunology. 3: 877-88. PMID 1931814 DOI: 10.1093/Intimm/3.9.877  0.355
1991 Rothman P, Li SC, Gorham B, Glimcher L, Alt F, Boothby M. Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line epsilon transcripts. Molecular and Cellular Biology. 11: 5551-61. PMID 1922063 DOI: 10.1128/Mcb.11.11.5551  0.383
1991 Grusby MJ, Johnson RS, Papaioannou VE, Glimcher LH. Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice Science. 253: 1417-1420. PMID 1910207 DOI: 10.1126/Science.1910207  0.431
1991 Ono SJ, Liou HC, Davidon R, Strominger JL, Glimcher LH. Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos Proceedings of the National Academy of Sciences of the United States of America. 88: 4309-4312. PMID 1903538 DOI: 10.1073/Pnas.88.10.4309  0.345
1991 Kara CJ, Glimcher LH. In vivo foot printing of MHC class II genes: Bare promoters in the bare lymphocyte syndrome Science. 252: 709-712. PMID 1902592 DOI: 10.1126/Science.1902592  0.378
1991 Liou HC, Eddy R, Shows T, Lisowska-Grospierre B, Griscelli C, Doyle C, Mannhalter J, Eibl M, Glimcher LH. An HLA-DR alpha promoter DNA-binding protein is expressed ubiquitously and maps to human chromosomes 22 and 5. Immunogenetics. 34: 286-92. PMID 1718857 DOI: 10.1007/Bf00211992  0.341
1991 Ivashkiv LB, Glimcher LH. Repression of class II major histocompatibility complex genes by cyclic AMP is mediated by conserved promoter elements Journal of Experimental Medicine. 174: 1583-1592. PMID 1660527 DOI: 10.1084/Jem.174.6.1583  0.364
1990 Wuthrich RP, Glimcher LH, Yui MA, Jevnikar AM, Dumas SE, Kelley VE. MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells. Kidney International. 37: 783-92. PMID 2407890 DOI: 10.1038/Ki.1990.46  0.392
1990 Grusby MJ, Mitchell SC, Nabavi N, Glimcher LH. Casein expression in cytotoxic T lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 87: 6897-6901. PMID 2395885 DOI: 10.1073/Pnas.87.17.6897  0.351
1990 Brown MA, Griffith IJ, Glimcher LH. Functional and molecular characterization of I-Aβk mutants is consistent with the predicted three dimensional structure of class II MHC molecules Molecular Immunology. 27: 645-650. PMID 2395436 DOI: 10.1016/0161-5890(90)90007-M  0.337
1990 Finn PW, Van TT, Accolla RS, Glimcher LH. Loss of a DNA-protein complex correlates with extinguished major histocompatibility complex class II expression in a human B cell. The Journal of Experimental Medicine. 171: 2159-64. PMID 2351936 DOI: 10.1084/Jem.171.6.2159  0.351
1990 Liou HC, Boothby MR, Finn PW, Davidon R, Nabavi N, Zeleznik-Le NJ, Ting JP, Glimcher LH. A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter. Science (New York, N.Y.). 247: 1581-4. PMID 2321018 DOI: 10.1126/Science.2321018  0.342
1990 Grusby MJ, Nabavi N, Wong H, Dick RF, Bluestone JA, Schotz MC, Glimcher LH. Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase Cell. 60: 451-459. PMID 2302735 DOI: 10.1016/0092-8674(90)90596-7  0.387
1990 Scholl PR, Sekaly RP, Diez A, Glimcher LH, Geha RS. Binding of toxic shock syndrome toxin-1 to murine major histocompatibility complex class II molecules European Journal of Immunology. 20: 1911-1916. PMID 2209697 DOI: 10.1002/Eji.1830200907  0.346
1990 Boothby M, Liou HC, Finn PW, Gravallese E, Glimcher LH. Control of transcription at the murine Aα locus Immunologic Research. 9: 77-92. PMID 2189937 DOI: 10.1007/Bf02918199  0.347
1990 Ivashkiv LB, Liou HC, Kara CJ, Lamph WW, Verma IM, Glimcher LH. mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element. Molecular and Cellular Biology. 10: 1609-21. PMID 2138707 DOI: 10.1128/Mcb.10.4.1609  0.305
1990 Nabavi N, Grusby MJ, Finn PW, Wolgemuth DJ, Glimcher LH. Identification of an Il-4-Inducible Gene Expressed in Differentiating Lymphocytes and Male Germ Cells Developmental Immunology. 1: 19-30. PMID 2136202 DOI: 10.1155/1990/94056  0.409
1990 Finn PW, Kara CJ, Douhan J, Van TT, Folsom V, Glimcher LH. Interferon γ regulates binding of two nuclear protein complexes in a macrophage cell line Proceedings of the National Academy of Sciences of the United States of America. 87: 914-918. PMID 2105504 DOI: 10.1073/Pnas.87.3.914  0.348
1990 Jevnikar AM, Wuthrich RP, Takei F, Xu HW, Brennan DC, Glimcher LH, Rubin-Kelley VE. Differing regulation and function of ICAM-1 and class II antigens on renal tubular cells. Kidney International. 38: 417-25. PMID 1977950 DOI: 10.1038/Ki.1990.221  0.439
1990 Finn P, Kara C, Van T, Douhan J, Boothby M, Glimcher L. The presence of a DNA binding complex correlates with E beta class II MHC gene expression. The Embo Journal. 9: 1543-1549. DOI: 10.1002/J.1460-2075.1990.Tb08273.X  0.375
1989 Ghogawala Z, Choi E, Daly KR, Blanco LR, Griffith IJ, Glimcher LH. An intronic 10-base-pair deletion in a class II Aβ gene affects RNA processing Molecular and Cellular Biology. 9: 4402-4408. PMID 2555693 DOI: 10.1128/Mcb.9.10.4402  0.343
1989 Gravallese EM, Boothby MR, Smas CM, Glimcher LH. A lipopolysaccharide-induced DNA-binding protein for a class II gene in B cells is distinct from NF-κB Molecular and Cellular Biology. 9: 3184-3192. PMID 2477682 DOI: 10.1128/Mcb.9.8.3184  0.356
1989 St-Pierre Y, Nabavi N, Ghogawala Z, Glimcher LH, Watts TH. A functional role for signal transduction via the cytoplasmic domains of MHC class II proteins Journal of Immunology. 143: 808-812. PMID 2473111  0.321
1988 Liou HC, Polla BS, Aragnol D, Leserman LD, Griffith IJ, Glimcher LH. A tissue-specific DNase I-hypersensitive site in a class II A alpha gene is under trans-regulatory control. Proceedings of the National Academy of Sciences of the United States of America. 85: 2738-42. PMID 3258662 DOI: 10.1073/Pnas.85.8.2738  0.316
1988 Boothby M, Gravallese E, Liou HC, Glimcher LH. A DNA binding protein regulated by IL-4 and by differentiation in B cells Science. 242: 1559-1562. PMID 3144043 DOI: 10.1126/Science.3144043  0.44
1988 Liou HC, Boothby MR, Glimcher LH. Distinct cloned class II MHC DNA binding proteins recognize the X box transcription element Science. 242: 69-71. PMID 3140376 DOI: 10.1126/Science.3140376  0.33
1988 Griffith IJ, Nabavi N, Ghogawala Z, Chase CG, Rodriguez M, McKean DJ, Glimcher LH. Structural mutation affecting intracellular transport and cell surface expression of murine class II molecules. The Journal of Experimental Medicine. 167: 541-55. PMID 3126253 DOI: 10.1084/Jem.167.2.541  0.307
1988 Griffith IJ, Ghogawala Z, Nabavi N, Golan DE, Myer A, McKean DJ, Glimcher LH. Cytoplasmic domain affects membrane expression and function of an Ia molecule. Proceedings of the National Academy of Sciences of the United States of America. 85: 4847-51. PMID 2838848 DOI: 10.1073/Pnas.85.13.4847  0.333
1987 Griffith IJ, Choi EM, Glimcher LH. A single base mutation in an I-A α-chain gene alters T-cell recognition Proceedings of the National Academy of Sciences of the United States of America. 84: 1090-1093. PMID 3493486 DOI: 10.1073/Pnas.84.4.1090  0.374
1987 Glimcher LH, Griffith IJ. Mutations of class II MHC molecules Trends in Immunology. 8: 279-282. DOI: 10.1016/0167-5699(87)90188-5  0.361
1986 Polla BS, Poljak A, Geier SG, Nathenson SG, Ohara J, Paul WE, Glimcher LH. Three distinct signals can induce class II gene expression in a murine pre-B-cell line. Proceedings of the National Academy of Sciences of the United States of America. 83: 4878-82. PMID 3487783 DOI: 10.1073/Pnas.83.13.4878  0.542
1986 Polla BS, Poljak A, Ohara J, Paul WE, Glimcher LH. Regulation of class II gene expression: Analysis in B cell stimulatory factor 1-inducible murine pre-B cell lines Journal of Immunology. 137: 3332-3337. PMID 3095428  0.475
1986 Chatterjee-Das S, Schlauder GG, Sachs DH, Glimcher LH, Paul WE, McKean DJ. A biochemical analysis of Ak molecules from mutant antigen presenting cell lines. Immunogenetics. 23: 121-5. PMID 3082750 DOI: 10.1007/Bf00377972  0.492
1986 Hattori M, Buse JB, Jackson RA, Glimcher L, Dorf ME, Minami M, Makino S, Moriwaki K, Kuzuya H, Imura H, Strauss WM, Seidman JG, Eisenbarth GS. The NOD Mouse: Recessive Diabetogenic Gene in the Major Histocompatibility Complex Science. 231: 733-735. PMID 3003909 DOI: 10.1126/Science.3003909  0.383
1986 Cohn LE, Glimcher LH, Waldmann RA, Smith JA, Ben-Nun A, Seidman JG, Choi E. Identification of functional regions on the I-Ab molecule by site-directed mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 83: 747-51. PMID 2418441 DOI: 10.1073/Pnas.83.3.747  0.394
1985 Malek TR, Chan C, Glimcher LH, Germain RN, Shevach EM. Influence of accessory cell and T cell surface antigens on mitogen-induced IL 2 receptor expression Journal of Immunology. 135: 1826-1833. PMID 3926885  0.309
1985 Ben-Nun A, Strauss W, Leeman SA, Cohn LE, Murre C, Duby A, Seidman JG, Glimcher LH. An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells. Immunogenetics. 22: 123-30. PMID 3875550 DOI: 10.1007/Bf00563509  0.446
1985 Schlauder GG, Bell MP, paul WE, Glimcher LH, McKean DJ. Biochemical characterization of I-Ak proteins from mutant antigen-presenting B-cell-B-lymphoma hybridomas Molecular Immunology. 22: 597-607. PMID 3875018 DOI: 10.1016/0161-5890(85)90184-1  0.492
1985 Mizuochi T, Golding H, Rosenberg AS, Glimcher LH, Malek TR, Singer A. Both L3T4+ and Lyt-2+ helper T cells initiate cytotoxic T lymphocyte responses against allogeneic major histocompatibility antigens but not against trinitrophenyl-modified self Journal of Experimental Medicine. 162: 427-443. PMID 3160804 DOI: 10.1084/Jem.162.2.427  0.429
1985 Glimcher LH, Schwartz RH. Analysis of responder cell-cell interactions in the syngeneic mixed leukocyte response Cellular Immunology. 93: 157-167. PMID 3158406 DOI: 10.1016/0008-8749(85)90396-X  0.417
1985 Allen PM, McKean DJ, Beck BN, Sheffield J, Glimcher LH. Direct evidence that a class II molecule and a simple globular protein generate multiple determinants Journal of Experimental Medicine. 162: 1264-1274. PMID 2413156 DOI: 10.1084/Jem.162.4.1264  0.405
1985 Heilig JS, Glimcher LH, Kranz DM, Clayton LK, Greenstein JL, Saito H, Maxam AM, Burakoff SJ, Eisen HN, Tonegawa S. Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants. Nature. 317: 68-70. PMID 2412133 DOI: 10.1038/317068A0  0.415
1984 Ben-Nun A, Glimcher LH, Weis J, Seidman JG. Functional expression of a cloned I-Aβk gene in B-lymphoma cells Science. 223: 825-828. PMID 6420890 DOI: 10.1126/Science.6420890  0.402
1983 Matis LA, Glimcher LH, Paul WE, Schwartz RH. Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules Proceedings of the National Academy of Sciences of the United States of America. 80: 6019-6023. PMID 6310611 DOI: 10.1073/Pnas.80.19.6019  0.534
1983 Glimcher LH, Kruisbeek AM, Paul WE, Green I. Functional activity of a transformed thymic epithelial cell line Scandinavian Journal of Immunology. 17: 1-11. PMID 6302828 DOI: 10.1111/J.1365-3083.1983.Tb00759.X  0.547
1983 Glimcher LH, Sharrow SO, Paul WE. Serologic and functional characterization of a panel of antigen-presenting cell lines expressing mutant I-A class II molecules Journal of Experimental Medicine. 158: 1573-1588. PMID 6195287 DOI: 10.1084/Jem.158.5.1573  0.522
1982 Glimcher LH, Cantor H. T-cell sets that control B-cell secretion of antigen-specific immunoglobulin also control secretion of nonspecific immunoglobulin Cellular Immunology. 70: 271-276. PMID 6982104 DOI: 10.1016/0008-8749(82)90328-8  0.421
1982 Glimcher LH, Kim KJ, Green I, Paul WE. Ia antigen-bearing B cell tumor lines can present protein antigen and alloantigen in a major histocompatibility complex-restricted fashion to antigen-reactive T cells Journal of Experimental Medicine. 155: 445-459. PMID 6460073 DOI: 10.1084/Jem.155.2.445  0.546
1982 Glimcher LH, Schwartz RH, Longo DL, Singer A. The specificity of the syngeneic mixed leukocyte response, a primary anti-I region T cell proliferative response, is determined intrathymically Journal of Immunology. 129: 987-991. PMID 6213713  0.341
1982 Glimcher LH, Shevach EM. Production of autoreactive I region-restricted T cell hybridomas Journal of Experimental Medicine. 156: 640-645. PMID 6212627 DOI: 10.1084/Jem.156.2.640  0.379
1982 Glimcher LH, Hamano T, Asofsky R, Herber-Katz E, Hedrick S, Schwartz RH, Paul WE. I region-restricted antigen presentation by B cell-B lymphoma hybridomas. Nature. 298: 283-4. PMID 6211627 DOI: 10.1038/298283A0  0.702
1982 Schwartz RH, Glimcher LH, Hedrick SM. Restriction of thymic major histocompatibility complex (MHC)- and immune response (Ir)-phenotype of T cells from allogeneic chimeras Behring Institute Mitteilungen. 155-162.  0.364
1981 Taurog JD, Raveche ES, Smathers PA, Glimcher LH, Huston DP, Hansen CT, Steinberg AD. T cell abnormalities in NZB mice occur independently of autoantibody production. The Journal of Experimental Medicine. 153: 221-34. PMID 6453918 DOI: 10.1084/Jem.153.2.221  0.416
1981 Glimcher LH, Longo DL, Green I, Schwartz RH. Murine syngeneic mixed lymphocyte response. I. Target antigens are self Ia molecules Journal of Experimental Medicine. 154: 1652-1670. PMID 6170721 DOI: 10.1084/Jem.154.5.1652  0.652
1978 Burakoff SJ, Finberg R, Glimcher L, Lemonnier F, Benacerraf B, Cantor H. The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens. The Journal of Experimental Medicine. 148: 1414-22. PMID 214510 DOI: 10.1084/Jem.148.5.1414  0.424
1977 Glimcher L, Shen FW, Cantor H. Identification of a cell-surface antigen selectively expressed on the natural killer cell. Journal of Experimental Medicine. 145: 1-9. PMID 187714 DOI: 10.1084/Jem.145.1.1  0.335
Low-probability matches (unlikely to be authored by this person)
2011 Hetz C, Martinon F, Rodriguez D, Glimcher LH. The unfolded protein response: integrating stress signals through the stress sensor IRE1α. Physiological Reviews. 91: 1219-43. PMID 22013210 DOI: 10.1152/Physrev.00001.2011  0.3
2003 Siebler J, Wirtz S, Weigmann B, Lehr HA, Glimcher LH, Galle PR, Neurath MF. A key pathogenic role for the statl-T-bet signaling pathway in con a-induced liver injury Gastroenterology. 124: A719. DOI: 10.1016/S0016-5085(03)83630-2  0.3
1995 Glimcher LH, Ivashkiv LB. Repression of Constitutive and Interferon-gamma-Induced Class II Major Histocompatibility Complex Genes by Cyclic AMP and Prostaglandins. American Journal of Therapeutics. 2: 676. PMID 11854845 DOI: 10.1097/00045391-199509000-00016  0.299
1990 Kara CJ, Liou HC, Ivashkiv LB, Glimcher LH. A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain Molecular and Cellular Biology. 10: 1347-1357. PMID 2320002 DOI: 10.1128/Mcb.10.4.1347  0.298
2000 Tsai EY, Falvo JV, Tsytsykova AV, Barczak AK, Reimold AM, Glimcher LH, Fenton MJ, Gordon DC, Dunn IF, Goldfeld AE. A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo. Molecular and Cellular Biology. 20: 6084-94. PMID 10913190 DOI: 10.1128/Mcb.20.16.6084-6094.2000  0.298
2019 Chopra S, Giovanelli P, Alvarado-Vazquez PA, Alonso S, Song M, Sandoval TA, Chae CS, Tan C, Fonseca MM, Gutierrez S, Jimenez L, Subbaramaiah K, Iwawaki T, Kingsley PJ, Marnett LJ, ... ... Glimcher LH, et al. IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain. Science (New York, N.Y.). 365. PMID 31320508 DOI: 10.1126/Science.Aau6499  0.298
1994 Gonzalez-Gay MA, Nabozny GH, Bull MJ, Zanelli E, Douhan J, Griffiths MM, Glimcher LH, Luthra HS, David CS. Protective role of major histocompatibility complex class II Ebd transgene on collagen-induced arthritis. The Journal of Experimental Medicine. 180: 1559-64. PMID 7931088 DOI: 10.1084/Jem.180.4.1559  0.297
2016 Martínez G, Vidal RL, Mardones P, Serrano FG, Ardiles AO, Wirth C, Valdés P, Thielen P, Schneider BL, Kerr B, Valdés JL, Palacios AG, Inestrosa NC, Glimcher LH, Hetz C. Regulation of Memory Formation by the Transcription Factor XBP1. Cell Reports. PMID 26854229 DOI: 10.1016/J.Celrep.2016.01.028  0.296
2011 Lee JH, Giannikopoulos P, Duncan SA, Wang J, Johansen CT, Brown JD, Plutzky J, Hegele RA, Glimcher LH, Lee AH. The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism. Nature Medicine. 17: 812-5. PMID 21666694 DOI: 10.1038/Nm.2347  0.295
2004 Erlebacher A, Price KA, Glimcher LH. Maintenance of mouse trophoblast stem cell proliferation by TGF-β/activin Developmental Biology. 275: 158-169. PMID 15464579 DOI: 10.1016/J.Ydbio.2004.07.032  0.294
2008 Hetz C, Glimcher L. The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology. Trends in Cell Biology. 18: 38-44. PMID 18077169 DOI: 10.1016/J.Tcb.2007.10.003  0.292
2004 Erlebacher A, Zhang D, Parlow AF, Glimcher LH. Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system Journal of Clinical Investigation. 114: 39-48. PMID 15232610 DOI: 10.1172/Jci20645  0.29
1985 Makoul GT, Robinson DR, Bhalla AK, Glimcher LH. Prostaglandin E2 inhibits the activation of cloned T cell hybridomas Journal of Immunology. 134: 2645-2659. PMID 2857750  0.29
1983 Dos Reis GA, Glimcher LH, Shevach EM. T cell clones and hybridomas as probes for the analysis of the syngeneic mixed leukocyte reaction Behring Institute Mitteilungen. 59-66. PMID 6242340  0.288
2012 Ermann J, Glimcher LH. After GWAS: mice to the rescue? Current Opinion in Immunology. 24: 564-70. PMID 23031443 DOI: 10.1016/J.Coi.2012.09.005  0.288
2021 Yang R, Weisshaar M, Mele F, Benhsaien I, Dorgham K, Han J, Croft CA, Notarbartolo S, Rosain J, Bastard P, Puel A, Fleckenstein B, Glimcher LH, Di Santo JP, Ma CS, et al. High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency. The Journal of Experimental Medicine. 218. PMID 34160550 DOI: 10.1084/jem.20202726  0.287
1993 Kara CJ, Glimcher LH. Developmental and Cytokine-Mediated Regulation of MHC Class II Gene Promoter Occupancy in Vivo Journal of Immunology. 150: 4934-4942. PMID 8496595  0.287
2004 Dorfman DM, van den Elzen P, Weng AP, Shahsafaei A, Glimcher LH. Differential expression of T-bet, a T-box transcription factor required for Th1 T-cell development, in peripheral T-cell lymphomas. American Journal of Clinical Pathology. 120: 866-73. PMID 14671975 DOI: 10.1309/MLUF-X0HR-5B96-GVAX  0.286
2009 Huh WJ, Esen E, Bredemeyer A, Shi G, Lee A, Konieczny SF, Glimcher LH, Mills JC. 863 XBP1 Is Required for the Maturation and the Maintenance of Digestive-Enzyme Secreting Zymogenic (Chief) Cells Gastroenterology. 136: A-132. DOI: 10.1016/S0016-5085(09)60592-8  0.284
2010 Garrett WS, Gallini CA, Yatsunenko T, Michaud M, DuBois A, Delaney ML, Punit S, Karlsson M, Bry L, Glickman JN, Gordon JI, Onderdonk AB, Glimcher LH. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host & Microbe. 8: 292-300. PMID 20833380 DOI: 10.1016/J.Chom.2010.08.004  0.284
2003 Lyon MF, Jamieson RV, Perveen R, Glenister PH, Griffiths R, Boyd Y, Glimcher LH, Favor J, Munier FL, Black GCM. A dominant mutation within the DNA-binding domain of the bZIP transcription factor Maf causes murine cataract and results in selective alteration in DNA binding Human Molecular Genetics. 12: 585-594. DOI: 10.1093/Hmg/Ddg063  0.284
1984 Bhalla AK, Amento EP, Serog B, Glimcher LH. 1,25-dihydroxyvitamin D3 inhibits antigen-induced T cell activation Journal of Immunology. 133: 1748-1754. PMID 6206136  0.284
2011 Jones D, Glimcher LH, Aliprantis AO. Osteoimmunology at the nexus of arthritis, osteoporosis, cancer, and infection. The Journal of Clinical Investigation. 121: 2534-42. PMID 21737885 DOI: 10.1172/Jci46262  0.282
2011 Matus S, Glimcher LH, Hetz C. Protein folding stress in neurodegenerative diseases: a glimpse into the ER. Current Opinion in Cell Biology. 23: 239-52. PMID 21288706 DOI: 10.1016/J.Ceb.2011.01.003  0.281
2009 Lee AH, Glimcher LH. Intersection of the unfolded protein response and hepatic lipid metabolism. Cellular and Molecular Life Sciences : Cmls. 66: 2835-50. PMID 19468685 DOI: 10.1007/S00018-009-0049-8  0.28
1994 Mombaerts P, Mizoguchi E, Ljunggren HG, Iacomini J, Ishikawa H, Wang L, Grusby MJ, Glimcher LH, Winn HJ, Bhan AK. Peripheral lymphoid development and function in TCR mutant mice. International Immunology. 6: 1061-70. PMID 7947457 DOI: 10.1093/Intimm/6.7.1061  0.28
1985 Glimcher LH, Serog B, McKean DJ, Beck BN. Evidence that autoreactive T hybridomas recognize multiple epitopes on the I-A(k) molecule Journal of Immunology. 134: 1780-1786. PMID 2578521  0.28
2017 Cubillos-Ruiz JR, Bettigole SE, Glimcher LH. Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer. Cell. 168: 692-706. PMID 28187289 DOI: 10.1016/J.Cell.2016.12.004  0.275
1995 Hodge MR, Rooney JW, Glimcher LH. The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites that bind at least two distinct factors Journal of Immunology. 154: 6397-6405. PMID 7759876  0.275
2013 Park TY, Kim SH, Shin YC, Lee NH, Lee RK, Shim JH, Glimcher LH, Mook-Jung I, Cheong E, Kim WK, Honda F, Morio T, Lim JS, Lee SK. Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin. Journal of Controlled Release : Official Journal of the Controlled Release Society. 166: 307-15. PMID 23298615 DOI: 10.1016/J.Jconrel.2012.12.022  0.274
2009 Hetz C, Lee AN, Gonzalez-Romero D, Thielen P, Castilla J, Soto C, Glimcher LH. Erratum: Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis (Proceedings of the National Academy of Sciences of the United States of America (2008) 105:2 (757-762) DOI: 10.1073/pnas.0711094105) Proceedings of the National Academy of Sciences of the United States of America. 106. DOI: 10.1073/Pnas.0902353106  0.273
2010 Schramek D, Leibbrandt A, Sigl V, Kenner L, Pospisilik JA, Lee HJ, Hanada R, Joshi PA, Aliprantis A, Glimcher L, Pasparakis M, Khokha R, Ormandy CJ, Widschwendter M, Schett G, et al. Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. Nature. 468: 98-102. PMID 20881962 DOI: 10.1038/Nature09387  0.271
1979 Cantor H, Kasai M, Shen FW, Leclerc JC, Glimcher L. Immunogenetic analysis of "natural killer" activity in the mouse. Immunological Reviews. 44: 3-12. PMID 83960 DOI: 10.1111/J.1600-065X.1979.Tb00265.X  0.27
1993 Markowitz JS, Rogers PR, Grusby MJ, Parker DC, Glimcher LH. B lymphocyte development and activation independent of MHC class II expression Journal of Immunology. 150: 1223-1233. PMID 8432977  0.268
2003 Nagaishi T, Iijima H, Pao L, Glickman JN, Glimcher LH, Neel BG, Blumberg RS. SHP-1 dependent and independent suppression of colitis by a CEACAM1 isoform expressing a long cytoplasmic tail Gastroenterology. 124: A35. DOI: 10.1016/S0016-5085(03)80173-7  0.267
2012 Shim JH, Greenblatt MB, Singh A, Brady N, Hu D, Drapp R, Ogawa W, Kasuga M, Noda T, Yang SH, Lee SK, Rebel VI, Glimcher LH. Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice (Journal of Clinical Investigation (2012) 122, 1 (91-106) DOI: 10.1172/JCI59466) Journal of Clinical Investigation. 122: 1948. DOI: 10.1172/Jci63413  0.264
2009 Glimcher LH, Lee AH. From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis. Annals of the New York Academy of Sciences. 1173: E2-9. PMID 19751410 DOI: 10.1111/J.1749-6632.2009.04956.X  0.264
1993 Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules. The Journal of Experimental Medicine. 178: 1701-12. PMID 8228817 DOI: 10.1084/Jem.178.5.1701  0.263
2016 Greenblatt MB, Shin DY, Oh H, Lee KY, Zhai B, Gygi SP, Lotinun S, Baron R, Liu D, Su B, Glimcher LH, Shim JH. MEKK2 mediates an alternative β-catenin pathway that promotes bone formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884171 DOI: 10.1073/Pnas.1600813113  0.263
2022 Dong H, Ham JD, Hu G, Xie G, Vergara J, Liang Y, Ali A, Tarannum M, Donner H, Baginska J, Abdulhamid Y, Dinh K, Soiffer RJ, Ritz J, Glimcher LH, et al. Memory-like NK cells armed with a neoepitope-specific CAR exhibit potent activity against NPM1 mutated acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 119: e2122379119. PMID 35696582 DOI: 10.1073/pnas.2122379119  0.262
1998 Sabatine MS, Laufer T, Glimcher LH, Widmer M, Winn H, Auchincloss H. Delayed rejection of soluble tumor necrosis factor receptor-secreting tumor allografts Transplantation. 65: 113-120. PMID 9448155 DOI: 10.1097/00007890-199801150-00022  0.26
2016 Bettigole SE, Glimcher LH. Novel roles for XBP1 in hematopoietic development. Cell Cycle (Georgetown, Tex.). 0. PMID 27058464 DOI: 10.1080/15384101.2016.1172470  0.258
2004 Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Görgün C, Glimcher LH, Hotamisligil GS. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science (New York, N.Y.). 306: 457-61. PMID 15486293 DOI: 10.1126/Science.1103160  0.258
1987 Griffith IJ, Carland FM, Glimcher LH. Alteration of a non-polymorphic residue in a class II E(β) gene eliminates an antibody-defined epitope without affecting T cell recognition Journal of Immunology. 138: 4480-4483. PMID 2438346  0.257
1990 Wuthrich RP, Jevnikar AM, Takei F, Glimcher LH, Kelley VE. Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis American Journal of Pathology. 136: 441-450. PMID 1968316  0.256
2010 Garrett WS, Gordon JI, Glimcher LH. Homeostasis and inflammation in the intestine. Cell. 140: 859-70. PMID 20303876 DOI: 10.1016/J.Cell.2010.01.023  0.256
1984 Beck BN, Glimcher LH, Nilson AE, Pierres M, McKean DJ. The structure-function relationship of I-A molecules: Correlation of serologic and functional phenotypes of four I-A(k) mutant cell lines Journal of Immunology. 133: 3176-3182. PMID 6333456  0.253
2012 Hu Y, Park KK, Yang L, Wei X, Yang Q, Cho KS, Thielen P, Lee AH, Cartoni R, Glimcher LH, Chen DF, He Z. Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells. Neuron. 73: 445-52. PMID 22325198 DOI: 10.1016/J.Neuron.2011.11.026  0.251
2003 SIEBLER J, WIRTZ S, PROTSCHKA M, GLIMCHER L, BLESSING M, GALLE P, NEURATH M. 193 Interferon γ signaling pathway plays a key role in CON a induced liver injury Hepatology. 38: 249-249. DOI: 10.1016/S0270-9139(03)80236-7  0.249
2012 Cho JA, Lee A, Plazer B, Harding HP, Ron D, Fiebiger E, Glimcher L, Kagan JC, Lencer WI. 1111 Innate Immune Sensing of a Bacterial Protein in the Endoplasmic Reticulum by Inositol-Requiring Enzyme 1 (Ire1α) Gastroenterology. 142: S-201. DOI: 10.1016/S0016-5085(12)60754-9  0.249
2012 Johansen CT, Wang J, McIntyre AD, Martins RA, Ban MR, Lanktree MB, Huff MW, Péterfy M, Mehrabian M, Lusis AJ, Kathiresan S, Anand SS, Yusuf S, Lee AH, Glimcher LH, et al. Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia. Circulation. Cardiovascular Genetics. 5: 66-72. PMID 22135386 DOI: 10.1161/Circgenetics.111.960864  0.248
2012 Jurczak MJ, Lee AH, Jornayvaz FR, Lee HY, Birkenfeld AL, Guigni BA, Kahn M, Samuel VT, Glimcher LH, Shulman GI. Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice. The Journal of Biological Chemistry. 287: 2558-67. PMID 22128176 DOI: 10.1074/Jbc.M111.316760  0.247
1991 Gravallese EM, Darling JM, Glimcher LH, Boothby M. Role of lipopolysaccharide and IL-4 in control of transcription of the class II A alpha gene. Journal of Immunology (Baltimore, Md. : 1950). 147: 2377-83. PMID 1918969  0.246
1994 Lederer JA, Liou JS, Todd MD, Glimcher LH, Lichtman AH. Regulation of cytokine gene expression in T helper cell subsets. Journal of Immunology (Baltimore, Md. : 1950). 152: 77-86. PMID 8254209  0.246
1989 Johnson NA, Carland F, Allen PM, Glimcher LH. T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-A(k)-restricted T helper hybridomas Journal of Immunology. 142: 3298-3304. PMID 2468715  0.234
1980 Glimcher LH, Steinberg AD, House SB, Green I. The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease Journal of Immunology. 125: 1832-1838. PMID 6447732  0.233
1991 Gravallese EM, Darling JM, Ladd AL, Katz JN, Glimcher LH. In situ hybridization studies of stromelysin and collagenase messenger RNA expression in rheumatoid synovium. Arthritis and Rheumatism. 34: 1076-84. PMID 1657007 DOI: 10.1002/Art.1780340903  0.231
1985 Glimcher LH, McKean DJ, Choi E, Seidman JG. Complex regulation of class II gene expression: Analysis with class II mutant cell lines Journal of Immunology. 135: 3542-3550. PMID 2995495  0.231
1991 Finn PW, Kara CJ, Grusby MJ, Folsom V, Glimcher LH. Upstream elements of the MHC class II Eβ gene active in B cells Journal of Immunology. 146: 4011-4015. PMID 1903416  0.23
1984 Cronin PS, Sing AP, Glimcher LH, Kelley VE, Reinisch CL. The isolation and functional characterization of autoimmune clones expressing inappropriate Ia Journal of Immunology. 133: 822-829. PMID 6610712  0.227
1988 McMillan VM, Dennis GJ, Glimcher LH, Finkelman FD, Mond JJ. Corticosteroid induction of Ig+Ia- B cells in vitro is mediated via interaction with the glucocorticoid cytoplasmic receptor Journal of Immunology. 140: 2549-2555. PMID 3258614  0.227
2008 Hetz C, Glimcher LH. XBP-1 and the UPRosome: Mastering secretory cell function Current Immunology Reviews. 4: 1-10. DOI: 10.2174/157339508783597280  0.226
1985 Glimcher LH, McKean DJ, Allen P. Autoreactive and hen egg lysozyme (HEL)-specific T cell hybridomas recognize multiple determinants on the I-A(K) molecule Federation Proceedings. 44.  0.226
2015 Zhang S, Ermann J, Succi MD, Zhou A, Hamilton MJ, Cao B, Korzenik JR, Glickman JN, Vemula PK, Glimcher LH, Traverso G, Langer R, Karp JM. An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease. Science Translational Medicine. 7: 300ra128. PMID 26268315 DOI: 10.1126/Scitranslmed.Aaa5657  0.225
1997 Zhou H, Su HS, Zhang X, Douhan J, Glimcher LH. CIITA-Dependent and -Independent Class II MHC Expression Revealed by a Dominant Negative Mutant Journal of Immunology. 158: 4741-4749. PMID 9144488  0.219
2021 Raundhal M, Ghosh S, Myers SA, Cuoco MS, Singer M, Carr SA, Waikar SS, Bonventre JV, Ritz J, Stone RM, Steensma DP, Regev A, Glimcher LH. Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias. Nature Immunology. PMID 33753942 DOI: 10.1038/s41590-021-00895-4  0.216
1983 Glimcher LH, Paul WE. Class II MHC antigens and immune response gene function: A mutational analysis Transplantation Proceedings. 15: 1753-1755.  0.215
2007 Hetz C, Thielen P, Fisher J, Pasinelli P, Brown RH, Korsmeyer S, Glimcher L. The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis Cell Death and Differentiation. 14: 1386-1389. PMID 17510659 DOI: 10.1038/Sj.Cdd.4402166  0.214
2022 Ghosh S, Raundhal M, Myers SA, Carr SA, Chen X, Petsko GA, Glimcher LH. Identification of RIOK2 as a master regulator of human blood cell development. Nature Immunology. 23: 109-121. PMID 34937919 DOI: 10.1038/s41590-021-01079-w  0.214
1990 Grusby MJ, Mitchell SC, Glimcher LH. Molecular cloning of mouse cathepsin D Nucleic Acids Research. 18: 4008. PMID 2374732 DOI: 10.1093/Nar/18.13.4008  0.213
1993 Lee R, Glimcher LH, Auchincloss H. Evidence that a 'four-cell cluster' may prime cytotoxic T-cells during graft rejection Transplantation Proceedings. 25: 847-849. PMID 8442245  0.21
2010 Glimcher L. Laurie Glimcher: merging cell biology and immune function. Interview by Sedwick Caitlin. The Journal of Cell Biology. 189: 192-3. PMID 20404104 DOI: 10.1083/jcb.1892pi  0.201
1987 Takahama Y, Ono S, Glimcher LH, Hamaoka T. Polyclonal B-cell activation by a B-cell differentiation factor B151-TRF2. IV. B151-TRF2-responsive F1 B cells consist of two separate populations capable of recognizing only one of the parental I-A products expressed on B cells Journal of Molecular and Cellular Immunology. 3: 177-194. PMID 3509923  0.199
1987 Glimcher LH, Polla BS, Poljak A, Morton CC, McKean DJ. Murine class II (Ia) molecules associate with human invariant chain Journal of Immunology. 138: 1519-1523. PMID 3468175  0.197
1989 Boothby M, Liou HC, Glimcher LH. Differences in DNA sequence specificity among MHC class II X box binding proteins Journal of Immunology. 142: 1005-1014. PMID 2492326  0.197
2009 Glimcher LH. Reflections on health care. The Journal of Clinical Investigation. 119: 2858-9. PMID 20069716 DOI: 10.1172/Jci40996  0.196
1993 Ponath PD, Fass D, Liou HC, Glimcher LH, Strominger JL. The regulatory gene, hXBP-1, and its target, HLA-DRA, utilize both common and distinct regulatory elements and protein complexes Journal of Biological Chemistry. 268: 17074-17082. PMID 8349596  0.193
2007 Kaser A, Lee A, Glickman J, Tilg H, Nieuwenhuis E, Higgins D, Glimcher L, Blumberg R. O01 TRANSCRIPTION FACTOR XBP1 REGULATES PANETH CELL FUNCTION AND INFLAMMATION IN THE INTESTINE Journal of Crohn's and Colitis Supplements. 1: 1-2. DOI: 10.1016/S1873-9954(07)70003-4  0.192
2016 Downs JA, Mathad JS, Reif LK, McNairy ML, Celum C, Boutin-Foster C, Deschamps MM, Gupta A, Hokororo A, Katz IT, Konopasek L, Nelson R, Riviere C, Glimcher LH, Fitzgerald DW. The ripple effect: why promoting female leadership in global health matters. Public Health Action. 6: 210-211. PMID 28123954 DOI: 10.5588/Pha.16.0072  0.188
2015 Davis MM, Glimcher LH. William Erwin Paul (1936-2015). Cell. 163: 529-30. PMID 26807452 DOI: 10.1016/J.Cell.2015.10.024  0.188
2004 Glimcher LH. How we can help the next generation of scientists: Introducing the "hands-on" primary caregiver's support program Journal of Immunology. 173: 2891-2892. PMID 15322140 DOI: 10.4049/Jimmunol.173.5.2891  0.187
2015 Weigmann B, Nemetz A, Becker C, Glimcher L, Neurath M. Transkriptionsfaktor c-maf reguliert Dünndarmentzündung Zeitschrift Fur Gastroenterologie. 41: 88. DOI: 10.1055/S-0035-1555290  0.187
2012 Glimcher L. Breaking down barriers to clinical translation: an interview with Laurie Glimcher. Interview by Sarah Allan. Disease Models & Mechanisms. 5: 6-8. PMID 22228788 DOI: 10.1242/Dmm.009191  0.182
1992 Ivashkiv LB, Fleming MD, Glimcher LH. Dominant negative mutants of transcription factor mXBP (CRE-BP1, ATF-2) The New Biologist. 4: 360-368. PMID 1622931  0.18
1990 Fontaine B, Hanson MP, Liou HC, Glimcher LH, Rouleau GA, Gusella JF. BanI polymorphism at the XBP1 locus. Nucleic Acids Research. 18: 5578. PMID 1977120 DOI: 10.1093/Nar/18.18.5578-A  0.176
2009 Glimcher LH, Lieberman J. Harvard's women four years later. Nature Immunology. 10: 559-61. PMID 19448653 DOI: 10.1038/Ni0609-559  0.174
2001 Glimcher LH. Lineage commitment in lymphocytes: Controlling the immune response Journal of Clinical Investigation. 108. PMID 11669073  0.164
2018 Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. Retraction Notice to: The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling. Cell Host & Microbe. 23: 571. PMID 29649448 DOI: 10.1016/j.chom.2018.03.005  0.153
1986 Quill H, Schwartz RH, Glimcher LH. E(β)(k) mutant antigen-presenting cell lines expressing altered A(α)(k) molecules Journal of Immunology. 136: 3351-3359. PMID 3082986  0.152
1993 Jevnikar AM, Singer GG, Coffman T, Glimcher LH, Kelley VER. Renal tubular cell expression of MHC class II (I-Eb) is insufficient to initiate immune injury in a transgenic kidney transplant model Transplantation Proceedings. 25: 142-143. PMID 8438254  0.145
1983 Glimcher LH, Schroer JA, Chan C, Shevach EM. Fine specificity of cloned insulin-specific T cell hybridomas: Evidence supporting a role for tertiary conformation Journal of Immunology. 131: 2868-2874. PMID 6196405  0.143
2003 Lyon MF, Jamieson RV, Perveen R, Glenister PH, Griffiths R, Boyd Y, Glimcher LH, Favor J, Munier FL, Black GC. A dominant mutation within the DNA-binding domain of the bZIP transcription factor Maf causes murine cataract and results in selective alteration in DNA binding. Human Molecular Genetics. 12: 585-94. PMID 12620964  0.142
1989 St-Pierre Y, Navabi N, Ghogawala Z, Glimcher L, Watts T. 3.2-06 The role of signalling through the cytoplasmic domains of MHC class II molecules in antigen presentation Human Immunology. 26: 19. DOI: 10.1016/0198-8859(89)90627-7  0.137
2013 Greenblatt MB, Shim JH, Zou W, Glimcher LH. A Tak1/p38 signaling axis regulates Runx2 activity and osteoblast functions Osteoimmunology: Interactions of the Immune and Skeletal Systems. 49-56. DOI: 10.1007/978-1-4614-5366-6_6  0.136
1993 Reimold AM, Kara CJ, Rooney JW, Glimcher LH. Transforming growth factor β1 repression of the HLA-DRα gene is mediated by conserved proximal promoter elements Journal of Immunology. 151: 4173-4182. PMID 8409394  0.13
2009 Glimcher LH. Foreword Protein Misfolding Disorders: a Trip Into the Er. DOI: 10.2174/97816080501301090101000i  0.12
2010 Kaser A, Lee A, Franke A, Glickman J, Zeissig S, Schreiber S, Glimcher L, Blumberg R. E09 ER stress, paneth cells and intestinal inflammation Journal of Crohn's and Colitis Supplements. 4: 8-9. DOI: 10.1016/S1873-9954(10)70013-6  0.113
2021 Raundhal M, Ghosh S, Myers SA, Cuoco MS, Singer M, Carr SA, Waikar SS, Bonventre JV, Ritz J, Stone RM, Steensma DP, Regev A, Glimcher LH. Author Correction: Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias. Nature Immunology. PMID 34522041 DOI: 10.1038/s41590-021-01031-y  0.112
1998 Matsushima G, Hiremath M, Smiley S, Glimcher L, Ting J, Suzuki K. The function of MHC class II molecules on microglia during demyelination Journal of Neuroimmunology. 90: 50. DOI: 10.1016/S0165-5728(98)91476-X  0.111
2020 Glimcher LH, Lee AH, Iwakoshi NN. Author Correction: XBP-1 and the unfolded protein response (UPR). Nature Immunology. PMID 33184511 DOI: 10.1038/s41590-020-00837-6  0.083
2011 Glimcher LH. A delicate balance: Science, medicine, and motherhood Medicine Science and Dreams: the Making of Physician-Scientists. 45-57. DOI: 10.1007/978-90-481-9538-1_4  0.037
2022 Glimcher LH, Petsko GA. Before you call the midwife. Cell. PMID 36174580 DOI: 10.1016/j.cell.2022.09.011  0.022
2021 Glimcher LH, Petsko GA. A lily worth gilding. Cell. PMID 34562359 DOI: 10.1016/j.cell.2021.08.008  0.019
2021 McNiff KK, Caligiuri MA, Davidson NE, Farrar W, Fisher RI, Glimcher LH, Hanners RB, Hwu P, Johnson CS, Pisters PWT, Thompson CB, Reddy AS, Jagels B, Kolosky JA, Ross T, et al. Improving Goal Concordant Care among Ten Leading Academic US Cancer Hospitals: A Collaboration of the Alliance of Dedicated Cancer Centers. The Oncologist. PMID 34076924 DOI: 10.1002/onco.13850  0.015
2012 Glimcher LH, Lindvall O, Aguirre V, Topalian SL, Musunuru K, Fauci AS. Translating research into therapies. Cell. 148: 1077-8. PMID 22532970 DOI: 10.1016/j.cell.2012.02.036  0.012
2011 Glimcher LH, Martinon F, Modlin RL. Editorial overview. Current Opinion in Immunology. 23: 1-2. PMID 21185707 DOI: 10.1016/j.coi.2010.12.001  0.01
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